Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mechanosensitive monoatomic ion channel activity	TMC7 TMC4 TMC3	1.94e-05	18	59	3	GO:0008381
GeneOntologyMolecularFunction	MutSalpha complex binding	ATR MCM9	1.79e-04	7	59	2	GO:0032407
GeneOntologyMolecularFunction	mismatch repair complex binding	ATR MCM9	4.64e-04	11	59	2	GO:0032404
GeneOntologyMolecularFunction	histone modifying activity	ATR ASH1L KDM8 KDM1B USP3	5.74e-04	229	59	5	GO:0140993
GeneOntologyCellularComponent	cell projection membrane	PLB1 TIRAP SPTBN1 PSD3 ROBO1 CUBN ENPEP	2.27e-04	431	60	7	GO:0031253
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTB SPTBN1	2.88e-04	9	60	2	GO:0014731
GeneOntologyCellularComponent	spectrin	SPTB SPTBN1	2.88e-04	9	60	2	GO:0008091
GeneOntologyCellularComponent	glutamatergic synapse	UBE3A SV2B NTRK3 SPTB SPTBN1 ROR2 STK38 PSD3 CPNE4	5.03e-04	817	60	9	GO:0098978
Domain	TMC	TMC7 TMC4 TMC3	1.66e-06	8	59	3	PF07810
Domain	TMC	TMC7 TMC4 TMC3	1.66e-06	8	59	3	IPR012496
Domain	Spectrin_bsu	SPTB SPTBN1	5.86e-05	4	59	2	IPR016343
Domain	TyrKc	JAK1 FRK NTRK3 ROR2	1.72e-04	88	59	4	SM00219
Domain	Tyr_kinase_cat_dom	JAK1 FRK NTRK3 ROR2	1.72e-04	88	59	4	IPR020635
Domain	PROTEIN_KINASE_TYR	JAK1 FRK NTRK3 ROR2	2.50e-04	97	59	4	PS00109
Domain	Tyr_kinase_AS	JAK1 FRK NTRK3 ROR2	2.50e-04	97	59	4	IPR008266
Domain	Copine	CPNE6 CPNE4	3.48e-04	9	59	2	PF07002
Domain	PH_dom-spectrin-type	SPTBN1 PSD3	3.48e-04	9	59	2	IPR001605
Domain	Copine	CPNE6 CPNE4	3.48e-04	9	59	2	IPR010734
Domain	Pkinase_Tyr	JAK1 FRK NTRK3 ROR2	7.37e-04	129	59	4	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	JAK1 FRK NTRK3 ROR2	9.48e-04	138	59	4	IPR001245
Domain	-	PSD3 ARFGEF1	1.00e-03	15	59	2	1.10.1000.11
Domain	Sec7	PSD3 ARFGEF1	1.00e-03	15	59	2	PF01369
Domain	Sec7_alpha_orthog	PSD3 ARFGEF1	1.00e-03	15	59	2	IPR023394
Domain	Sec7	PSD3 ARFGEF1	1.14e-03	16	59	2	SM00222
Domain	SEC7	PSD3 ARFGEF1	1.14e-03	16	59	2	PS50190
Domain	Sec7_dom	PSD3 ARFGEF1	1.14e-03	16	59	2	IPR000904
Domain	Actinin_actin-bd_CS	SPTB SPTBN1	2.38e-03	23	59	2	IPR001589
Domain	Spectrin	SPTB SPTBN1	2.38e-03	23	59	2	PF00435
Domain	ACTININ_2	SPTB SPTBN1	2.38e-03	23	59	2	PS00020
Domain	ACTININ_1	SPTB SPTBN1	2.38e-03	23	59	2	PS00019
Domain	Spectrin_repeat	SPTB SPTBN1	3.77e-03	29	59	2	IPR002017
Domain	Spectrin/alpha-actinin	SPTB SPTBN1	4.58e-03	32	59	2	IPR018159
Domain	SPEC	SPTB SPTBN1	4.58e-03	32	59	2	SM00150
Domain	PTPc	PTPN2 PTPN3	5.77e-03	36	59	2	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPN2 PTPN3	6.74e-03	39	59	2	PS50055
Pubmed	Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.	TMC7 TMC4 TMC3	2.86e-07	8	61	3	12906855
Pubmed	TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.	TMC7 TMC4 TMC3	2.86e-07	8	61	3	12812529
Pubmed	Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins.	PTPN3 UBE3A	3.03e-06	2	61	2	17166906
Pubmed	PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.	JAK1 PTPN2	3.03e-06	2	61	2	21551237
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	PSD3 ARFGEF1 ROBO1	4.88e-06	19	61	3	30674481
Pubmed	A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.	SPTB SPTBN1	9.07e-06	3	61	2	11294830
Pubmed	The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.	JAK1 PTPN2	9.07e-06	3	61	2	11909529
Pubmed	Multiple regions of E6AP (UBE3A) contribute to interaction with papillomavirus E6 proteins and the activation of ubiquitin ligase activity.	PTPN3 UBE3A	9.07e-06	3	61	2	31971989
Pubmed	The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.	SPTB SPTBN1	9.07e-06	3	61	2	8479293
Pubmed	β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.	SPTB SPTBN1	9.07e-06	3	61	2	32425157
Pubmed	Developmental expression of brain beta-spectrin isoform messenger RNAs.	SPTB SPTBN1	9.07e-06	3	61	2	1467942
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	JAK1 SPTB SPTBN1	1.15e-05	25	61	3	8493579
Pubmed	The protein tyrosine kinase family of the human genome.	JAK1 FRK NTRK3 ROR2	1.42e-05	83	61	4	11114734
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CD82 TIA1 DIPK1A DDHD1 SPTBN1 ASH1L KDM1B CUBN DDX21 USP3	1.77e-05	1084	61	10	11544199
Pubmed	The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.	SPTB SPTBN1	1.81e-05	4	61	2	21566095
Pubmed	Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.	SPTB SPTBN1	1.81e-05	4	61	2	3862089
Pubmed	Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.	SPTB SPTBN1	1.81e-05	4	61	2	21412925
Pubmed	Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signalling by the protein tyrosine phosphatase TCPTP.	JAK1 PTPN2	1.81e-05	4	61	2	18948751
Pubmed	In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target.	JAK1 PTPN2	1.81e-05	4	61	2	28723893
Pubmed	Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.	SPTB SPTBN1	1.81e-05	4	61	2	12820899
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	PTPN2 TMC7 TIRAP ROR2 MCM9 SLC19A2 ARFGEF1 KLHL14 GK5	2.96e-05	915	61	9	32393512
Pubmed	Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3.	SV2B NTRK3	4.52e-05	6	61	2	18367154
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	JAK1 FRK NTRK3 ROR2 STK38 KLHL14	4.86e-05	372	61	6	22939624
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	NTRK3 SPTBN1 PITPNA PSD3 ROBO1 CPNE4	7.77e-05	405	61	6	38187761
Pubmed	Substrate-trapping techniques in the identification of cellular PTP targets.	JAK1 PTPN2 PTPN3	8.93e-05	49	61	3	15588985
Pubmed	The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.	CPNE6 CPNE4	1.08e-04	9	61	2	9430674
Pubmed	Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.	PTPN2 PTPN3	1.08e-04	9	61	2	12907755
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SPTBN1 ROR2 STK38 PSD3 DDX21	1.17e-04	272	61	5	31010829
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	SPTB SPTBN1	1.35e-04	10	61	2	22159418
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	ASH1L LARS1 KLHL14 UNC79	1.55e-04	153	61	4	10718198
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTB SPTBN1	1.65e-04	11	61	2	17607528
Pubmed	DAMP molecule S100A9 acts as a molecular pattern to enhance inflammation during influenza A virus infection: role of DDX21-TRIF-TLR4-MyD88 pathway.	TIRAP DDX21	1.65e-04	11	61	2	24391503
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	ASH1L ACTL6B KDM8 KDM1B	1.71e-04	157	61	4	30186101
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTB SPTBN1	2.33e-04	13	61	2	18796539
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	ASH1L KDM1B	2.33e-04	13	61	2	24619213
Pubmed	Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.	JAK1 SPTBN1 STK38 DDX21	2.42e-04	172	61	4	23184937
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	JAK1 COL27A1 STK38 DDX21 UNC79	2.53e-04	321	61	5	32098917
Pubmed	Subcellular localization of intracellular protein tyrosine phosphatases in T cells.	PTPN2 PTPN3	2.72e-04	14	61	2	10940933
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PTPN2 DIPK1A DDHD1 SPTBN1 LARS1 KDM8 OGDH USP3 TMC3	2.99e-04	1242	61	9	30973865
Pubmed	Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.	PTPN2 PTPN3	3.57e-04	16	61	2	8875997
Pubmed	Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells.	NTRK3 ROBO1	3.57e-04	16	61	2	30661738
Pubmed	Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.	SV2B ROBO1	3.57e-04	16	61	2	17715346
Pubmed	LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.	LARS1 DDX21	4.05e-04	17	61	2	37072811
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	JAK1 UBE3A SPTBN1 LARS1 STK38 DDX21	4.08e-04	551	61	6	34728620
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTB SPTBN1	4.55e-04	18	61	2	12119179
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	PTPN2 SPTBN1 ROR2 STK38 ROBO1 CCDC25	4.79e-04	568	61	6	37774976
Pubmed	CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.	JAK1 ATR TIRAP	4.90e-04	87	61	3	29991678
Pubmed	HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine.	CUBN ENPEP	5.08e-04	19	61	2	31345929
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	JAK1 PTPN3 SPTBN1 PSD3 ROBO1	5.27e-04	377	61	5	38117590
Pubmed	Dengue hemorrhagic fever is associated with polymorphisms in JAK1.	JAK1 TIRAP SPTBN1	5.59e-04	91	61	3	20588308
Pubmed	Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.	SPTB SPTBN1	5.63e-04	20	61	2	18723693
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM8 KDM1B	6.22e-04	21	61	2	27626377
Pubmed	Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.	PSD3 CPNE4	6.83e-04	22	61	2	21507922
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	JAK1 ATR SPTBN1 STK38 DDX21	6.96e-04	401	61	5	25852190
Pubmed	Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.	JAK1 SPTBN1 STK38	7.57e-04	101	61	3	19167051
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	SPTBN1 LARS1 DDX21	8.24e-04	104	61	3	36055981
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CPNE6 SV2B SPTB SPTBN1 LARS1 PSD3 ACTL6B CPNE4 OGDH	8.31e-04	1431	61	9	37142655
Pubmed	Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.	SPTBN1 CPNE4	8.84e-04	25	61	2	12522145
Pubmed	TFAM is required for maturation of the fetal and adult intestinal epithelium.	CUBN ENPEP	9.57e-04	26	61	2	29684311
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	JAK1 SPTBN1 STK38 DDX21	1.08e-03	256	61	4	32698014
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PTPN2 SPTBN1 ROR2 PSD3 PTRH2 ROBO1 TTC17 DDX21 OGDH	1.09e-03	1487	61	9	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MALT1 SPTB ROR2 ERI3 ASH1L TTC17 TEP1 OGDH USP3	1.10e-03	1489	61	9	28611215
Pubmed	A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE).	CCDC198 CUBN	1.11e-03	28	61	2	17683524
Pubmed	Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.	UBE3A USP3	1.36e-03	31	61	2	36114200
Pubmed	Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.	PLB1 CUBN	1.36e-03	31	61	2	15583024
Pubmed	Murine txk: a protein tyrosine kinase gene regulated by T cell activation.	JAK1 FRK	1.45e-03	32	61	2	7542761
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SPTBN1 ROR2 LARS1 STK38 PSD3 ROBO1	1.50e-03	708	61	6	39231216
Pubmed	Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.	ROR2 ROBO1	1.54e-03	33	61	2	18480165
Pubmed	ROR2 Downregulation Activates the MSX2/NSUN2/p21 Regulatory Axis and Promotes Dental Pulp Stem Cell Senescence.	SPTBN1 ROR2 DDX21	1.60e-03	131	61	3	35356984
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	JAK1 PTPN3 CD82 ERI3 ROBO1 TTC17	1.62e-03	719	61	6	35337019
Interaction	TEP1 interactions	TIRAP ACTL6B KLHL14 TEP1	1.25e-05	48	60	4	int:TEP1
Cytoband	3q23	ATR GK5	1.58e-03	44	61	2	3q23
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	TMC7 SCNN1B KDM8	1.59e-03	172	61	3	chr16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr3q23	ATR GK5	3.22e-03	63	61	2	chr3q23
GeneFamily	Transmembrane channel likes	TMC7 TMC4 TMC3	6.48e-07	8	42	3	1135
GeneFamily	EF-hand domain containing\|Spectrins	SPTB SPTBN1	1.10e-04	7	42	2	1113
GeneFamily	Copines	CPNE6 CPNE4	1.88e-04	9	42	2	829
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN2 PTPN3	7.87e-04	18	42	2	812
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM8 KDM1B	1.41e-03	24	42	2	485
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	NTRK3 ROR2	3.89e-03	40	42	2	321
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	JAK1 PTPN3	6.01e-03	50	42	2	1293
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NTRK3 ROR2 ROBO1	6.17e-03	161	42	3	593
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTB SPTBN1 PSD3	1.21e-02	206	42	3	682
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_500	FRK CCDC198 TIA1 TMC7 SCNN1B LAMB3 FJX1 CUBN	1.27e-05	394	59	8	gudmap_developingLowerUrinaryTract_e15.5_urothelium_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_1000	FRK CCDC198 TIA1 TMC7 SLC19A2 SCNN1B LAMB3 FJX1 TMC4 CUBN	5.42e-05	784	59	10	gudmap_developingLowerUrinaryTract_e15.5_urothelium_1000
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500	PTPN3 SV2B ROBO1 FJX1 KLHL14	5.68e-05	148	59	5	gudmap_kidney_P3_CapMes_Crym_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000	PTPN2 FRK PTPN3 MOXD1 TMC7 ROR2 MCM9 LAMB3 ROBO1 TMC4	6.42e-05	800	59	10	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_500	MOXD1 TIA1 UBE3A SPTBN1 ASH1L	6.45e-05	152	59	5	gudmap_developingGonad_e18.5_epididymis_500_k4
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000	FRK PTPN3 CCDC198 TIA1 UBE3A MCM9 SCNN1B FJX1 TMC4 KLHL14	6.49e-05	801	59	10	gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_200	FRK CCDC198 TIA1 SCNN1B TMC4	8.23e-05	160	59	5	gudmap_developingKidney_e15.5_Medullary collecting duct_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_500	FRK MOXD1 TMC7 ROR2 LAMB3 ROBO1 TMC4	1.19e-04	401	59	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_200	PTPN3 CCDC198 ROBO1 FJX1 ENPEP	1.25e-04	175	59	5	gudmap_kidney_P4_CapMesRenVes_Crym_200
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_1000	FRK PTPN3 FJX1 TMC4 KLHL14	1.63e-04	185	59	5	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k4
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	FRK PTPN3 CCDC198 KCNT2 DIPK1A NTRK3 SCNN1B FJX1 CUBN ENPEP	1.77e-04	905	59	10	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#3_top-relative-expression-ranked_1000	CCDC198 TIA1 SLC19A2 FJX1 CUBN	2.18e-04	197	59	5	gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k3
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500	FRK CCDC198 KCNT2 NTRK3 FJX1 CUBN ENPEP	2.62e-04	456	59	7	gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	JAK1 MOXD1 CCDC198 TIA1 UBE3A SPTBN1 ASH1L KLHL14 ENPEP	3.30e-04	797	59	9	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	JAK1 MOXD1 TIA1 UBE3A NTRK3 COL27A1 SPTBN1 ASH1L ENPEP	3.36e-04	799	59	9	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	kidney_e13.5_Podocyte_MafB_k-means-cluster#2_top-relative-expression-ranked_500	KCNT2 PSD3 ENPEP	3.64e-04	50	59	3	gudmap_kidney_e13.5_Podocyte_MafB_k2_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	TIA1 UBE3A SPTBN1 ASH1L STK38	4.02e-04	225	59	5	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000	MOXD1 NTRK3 COL27A1 SPTBN1 ENPEP	4.80e-04	234	59	5	gudmap_developingGonad_e18.5_epididymis_1000_k5
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_500	PTPN3 SV2B ROBO1 FJX1 KLHL14 ENPEP	5.56e-04	370	59	6	gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500	MOXD1 UBE3A SPTBN1 ASH1L	5.58e-04	136	59	4	gudmap_developingGonad_P2_epididymis_500_k2
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#1_top-relative-expression-ranked_200	FRK TIA1 SCNN1B	5.64e-04	58	59	3	gudmap_developingKidney_e15.5_cortic collect duct_200_k1
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000	MOXD1 TIA1 UBE3A SPTBN1 ASH1L	6.36e-04	249	59	5	gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_200	PTPN3 ROBO1 FJX1	6.86e-04	62	59	3	gudmap_kidney_P4_CapMesRenVes_Crym_k3_200
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_1000	PTPN3 CCDC198 DIPK1A SCNN1B CUBN	7.21e-04	256	59	5	gudmap_kidney_P0_JuxtaGlom_Ren1_k4_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_200	UBE3A SPTBN1 ASH1L	7.53e-04	64	59	3	gudmap_developingGonad_e18.5_epididymis_200_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_500	FRK CCDC198 TIA1 SCNN1B LAMB3 TMC4	7.72e-04	394	59	6	gudmap_developingKidney_e15.5_Medullary collecting duct_500
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500	PTPN3 CCDC198 SV2B ROBO1 FJX1 ENPEP	8.14e-04	398	59	6	gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_top-relative-expression-ranked_200	FRK PTPN3 CCDC198 FJX1	8.25e-04	151	59	4	gudmap_kidney_e10.5_UretericTrunk_HoxB7_200
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#2_top-relative-expression-ranked_1000	FRK TIA1 SLC19A2 SCNN1B	8.46e-04	152	59	4	gudmap_developingKidney_e15.5_cortic collect duct_1000_k2
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_200	FRK CCDC198 TIA1 SCNN1B	9.32e-04	156	59	4	gudmap_developingKidney_e15.5_cortic collect duct_200
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#5_top-relative-expression-ranked_200	FRK TIA1 SCNN1B	9.37e-04	69	59	3	gudmap_developingKidney_e15.5_Medullary collecting duct_200_k5
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	TIA1 UBE3A SPTBN1 ASH1L STK38	1.03e-03	277	59	5	gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500	TIA1 UBE3A SPTBN1 ASH1L	1.07e-03	162	59	4	gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlas	DevelopingKidney_e11.5_ureteric bud_emap-3844_top-relative-expression-ranked_200	FRK PTPN3 CCDC198 KLHL14	1.07e-03	162	59	4	gudmap_developingKidney_e11.5_ureteric bud_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#5_top-relative-expression-ranked_1000	FRK TMC7 SCNN1B LAMB3 TMC4	1.08e-03	280	59	5	gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k5
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500	PTPN3 SV2B ROBO1 FJX1	1.15e-03	165	59	4	gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_500	MOXD1 ROR2 ROBO1	1.15e-03	74	59	3	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_500_k2
CoexpressionAtlas	mendel_RNAseq_e18.5_Urothelium_Krt5CreRFP_2500_K2	PTPN3 MOXD1 TMC7 SCNN1B LAMB3 TMC4	1.16e-03	426	59	6	mendel_RNAseq_e18.5_Urothelium_Krt5CreRFP_2500_K2
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN3 SCNN1B LAMB3 FJX1 TMC4	3.24e-06	166	61	5	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN3 SCNN1B LAMB3 FJX1 TMC4	3.24e-06	166	61	5	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNT2 SPTB PTPRQ CPNE4 ENPEP	4.68e-06	179	61	5	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRK PTPN3 LAMB3 TMC4 GK5	4.68e-06	179	61	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPN3 CCDC198 COL27A1 CUBN ENPEP	4.81e-06	180	61	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNT2 SPTB PTPRQ ROBO1 ENPEP	5.21e-06	183	61	5	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRK PTPN3 LAMB3 TMC4 GK5	5.35e-06	184	61	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	P15-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLB1 SCNN1B LAMB3 FJX1 TMC4	5.64e-06	186	61	5	521e6e007bbae73e7328153aa170cf04ca3c1093
ToppCell	P28-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLB1 SCNN1B LAMB3 FJX1 TMC4	5.79e-06	187	61	5	a4b41904ba05eb76212c949fc3ac197f906c8351
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	MALT1 KCNT2 COL27A1 CUBN ENPEP	6.10e-06	189	61	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 KCNT2 NTRK3 ROR2 ROBO1	6.58e-06	192	61	5	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRK PTPN3 CCDC198 CUBN ENPEP	6.92e-06	194	61	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MOXD1 KCNT2 COL27A1 ROR2 ROBO1	7.10e-06	195	61	5	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MOXD1 KCNT2 NTRK3 ROR2 ROBO1	7.46e-06	197	61	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 NTRK3 COL27A1 ROR2 ROBO1	7.46e-06	197	61	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	MOXD1 CD82 ROR2 PSD3 ROBO1	7.46e-06	197	61	5	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	MOXD1 KCNT2 COL27A1 ROR2 PSD3	7.83e-06	199	61	5	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	MOXD1 KCNT2 ROR2 ROBO1 ENPEP	7.83e-06	199	61	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Sepsis-Int-URO-Lymphocyte-B-B_intermediate\|Int-URO / Disease, condition lineage and cell class	MOXD1 CD82 DIPK1A ROR2 KLHL14	8.02e-06	200	61	5	221dd8d8851c47f2202ba848de3a041b17b1db3f
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	ACTL6B CPNE4 KLHL14 UNC79	4.08e-05	140	61	4	82b150e9e9962460a5cd6bef7ee04f28f5c05d1a
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PTPN3 SV2B PSD3 CPNE4	4.94e-05	147	61	4	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN3 CPNE6 SV2B SPIC	6.07e-05	155	61	4	72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KCNT2 ROR2 PTPRQ LAMB3	7.03e-05	161	61	4	0d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FRK DIPK1A COL27A1 SPIC	7.55e-05	164	61	4	eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PLB1 TMC7 DIPK1A SPIC	7.92e-05	166	61	4	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROR2 ROBO1 FJX1 SPIC	8.10e-05	167	61	4	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PTPN3 CPNE6 SV2B PSD3	8.29e-05	168	61	4	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 KCNT2 COL27A1 ROBO1	8.29e-05	168	61	4	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 COL27A1 ROR2 ROBO1	9.29e-05	173	61	4	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	KCNT2 SPTBN1 PTPRQ SCNN1B	9.50e-05	174	61	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.C1ql3_(VTA_(dorsal_VTA))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRQ LAMB3 CUBN	9.76e-05	65	61	3	4382d56d5f71c7acfe35f84db7257aba2a7dd36a
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.C1ql3_(VTA_(dorsal_VTA))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRQ LAMB3 CUBN	9.76e-05	65	61	3	05b712f83d88e864747cd0229a39aca17321e0f8
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRQ SCNN1B LAMB3 TMC4	1.01e-04	177	61	4	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC198 COL27A1 CUBN ENPEP	1.08e-04	180	61	4	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	KCNT2 SPTBN1 SCNN1B LAMB3	1.08e-04	180	61	4	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1A TIRAP DDHD1 GK5	1.08e-04	180	61	4	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIPK1A TIRAP DDHD1 GK5	1.08e-04	180	61	4	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 COL27A1 ROR2 ROBO1	1.08e-04	180	61	4	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 CUBN UNC79 ENPEP	1.11e-04	181	61	4	9542c19edc9bd2cba68c01c2a8407705398e3011
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRQ SCNN1B LAMB3 TMC4	1.11e-04	181	61	4	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD82 NTRK3 SPTB ENPEP	1.11e-04	181	61	4	59527ad218e49386b04cabb97d53d2ed55a35961
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRQ SCNN1B CPNE4 CUBN	1.11e-04	181	61	4	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTB PTPRQ CPNE4 ENPEP	1.11e-04	181	61	4	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 CUBN UNC79 ENPEP	1.11e-04	181	61	4	8f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTB PTPRQ CPNE4 ENPEP	1.11e-04	181	61	4	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	NTRK3 COL27A1 TMC4 ENPEP	1.13e-04	182	61	4	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 SCNN1B LAMB3 FJX1	1.13e-04	182	61	4	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLB1 SCNN1B LAMB3 FJX1	1.13e-04	182	61	4	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KCNT2 COL27A1 ROR2 ROBO1	1.13e-04	182	61	4	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC198 COL27A1 CUBN ENPEP	1.15e-04	183	61	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOXD1 PLB1 NTRK3 CUBN	1.15e-04	183	61	4	b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MOXD1 KCNT2 SV2B CPNE4	1.15e-04	183	61	4	01ad18f198195ce341bae01a1c8c253cc4607766
ToppCell	droplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOXD1 PLB1 NTRK3 CUBN	1.15e-04	183	61	4	19e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	CCDC198 COL27A1 CUBN ENPEP	1.18e-04	184	61	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|normal_Lung / Location, Cell class and cell subclass	MOXD1 COL27A1 ROR2 ROBO1	1.18e-04	184	61	4	0b336489c10e8c3c957795dd845454f03404382b
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLB1 SPTB SCNN1B LAMB3	1.18e-04	184	61	4	204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNT2 SPTBN1 PTPRQ SCNN1B	1.18e-04	184	61	4	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-club_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLB1 SPTB SCNN1B LAMB3	1.18e-04	184	61	4	9365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KCNT2 SPTBN1 PTPRQ SCNN1B	1.18e-04	184	61	4	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 SPTB SCNN1B LAMB3	1.18e-04	184	61	4	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 SPTB SCNN1B LAMB3	1.18e-04	184	61	4	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 SPTBN1 PTPRQ SCNN1B	1.20e-04	185	61	4	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	KCNT2 SPTBN1 PTPRQ SCNN1B	1.20e-04	185	61	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRK PTPN3 LAMB3 GK5	1.20e-04	185	61	4	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC198 COL27A1 CUBN ENPEP	1.20e-04	185	61	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNT2 SV2B LAMB3 CPNE4	1.20e-04	185	61	4	a1b2525da018abe458908cab7268bd403ee98d92
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DDHD1 MCM9 ASH1L TTC17	1.23e-04	186	61	4	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FRK CD82 KCNT2 ROBO1	1.25e-04	187	61	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	Control-Epithelial-ATI\|Control / Disease state, Lineage and Cell class	KCNT2 SPTBN1 SCNN1B LAMB3	1.25e-04	187	61	4	fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	MALT1 COL27A1 CUBN ENPEP	1.25e-04	187	61	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	MOXD1 COL27A1 ROR2 ROBO1	1.25e-04	187	61	4	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MALT1 CCDC198 COL27A1 ENPEP	1.25e-04	187	61	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 SPTBN1 PTPRQ SCNN1B	1.25e-04	187	61	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PTPN3 CCDC198 CUBN ENPEP	1.25e-04	187	61	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	KCNT2 SPTBN1 PTPRQ SCNN1B	1.25e-04	187	61	4	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE6 SV2B ACTL6B CPNE4	1.25e-04	187	61	4	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE6 SV2B ACTL6B CPNE4	1.25e-04	187	61	4	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE6 SV2B ACTL6B CPNE4	1.25e-04	187	61	4	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRK PTPN3 LAMB3 GK5	1.28e-04	188	61	4	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	facs-Lung-EPCAM-18m-Epithelial-Basal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1B LAMB3 FJX1 TMC4	1.31e-04	189	61	4	783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 KCNT2 ROR2 ROBO1	1.31e-04	189	61	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	KCNT2 COL27A1 ROR2 ROBO1	1.31e-04	189	61	4	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 KCNT2 ROR2 ROBO1	1.31e-04	189	61	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC198 COL27A1 CUBN ENPEP	1.31e-04	189	61	4	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC198 COL27A1 CUBN ENPEP	1.31e-04	189	61	4	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC198 COL27A1 CUBN ENPEP	1.31e-04	189	61	4	28b502611829e4a24caff2562545c7db97686099
ToppCell	facs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1B LAMB3 FJX1 TMC4	1.31e-04	189	61	4	88b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 CD82 SCNN1B TMC4	1.31e-04	189	61	4	27e5d706f10a6221f314faf642eede15deab3165
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL27A1 ROR2 PSD3 ROBO1	1.33e-04	190	61	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MOXD1 NTRK3 FJX1 ENPEP	1.33e-04	190	61	4	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRK SPTBN1 PITPNA ASH1L	1.36e-04	191	61	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	LAM-Epithelial-AT1\|LAM / Condition, Lineage and Cell class	KCNT2 SPTBN1 SCNN1B LAMB3	1.36e-04	191	61	4	66875b2ec2c510489407f3e433a90cdf74a15094
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRK SPTBN1 PITPNA ASH1L	1.36e-04	191	61	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRK SPTBN1 PITPNA ASH1L	1.36e-04	191	61	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOXD1 KCNT2 ROR2 ROBO1	1.39e-04	192	61	4	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	KCNT2 SPTBN1 SCNN1B LAMB3	1.39e-04	192	61	4	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	KCNT2 NTRK3 ROR2 ENPEP	1.39e-04	192	61	4	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MOXD1 NTRK3 FJX1 ENPEP	1.41e-04	193	61	4	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	facs-Lung-24m-Epithelial-alveolar_epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCNN1B LAMB3 TMC4 ENPEP	1.41e-04	193	61	4	4a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MOXD1 NTRK3 FJX1 ENPEP	1.41e-04	193	61	4	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTB SPTBN1	2.43e-05	4	60	2	DOID:0050882 (implicated_via_orthology)
Disease	adenoid cystic carcinoma (is_implicated_in)	ATR NTRK3	4.05e-05	5	60	2	DOID:0080202 (is_implicated_in)
Disease	tissue factor pathway inhibitor measurement	COL27A1 SLC19A2	8.48e-05	7	60	2	EFO_0007968
Disease	stomach cancer (is_implicated_in)	JAK1 NTRK3 TEP1	4.31e-04	72	60	3	DOID:10534 (is_implicated_in)
Disease	Glioma	ATR NTRK3 PSD3	7.50e-04	87	60	3	C0017638
Disease	eye colour measurement	PTPN3 TMC7 SV2B ROR2	1.02e-03	218	60	4	EFO_0009764
Disease	Prostatic Neoplasms	JAK1 ATR TIRAP ASH1L PTRH2 ROBO1	1.56e-03	616	60	6	C0033578
Disease	Malignant neoplasm of prostate	JAK1 ATR TIRAP ASH1L PTRH2 ROBO1	1.56e-03	616	60	6	C0376358
Disease	calcium measurement	FRK KCNT2 TIRAP SPTBN1 PSD3 PTRH2	1.71e-03	628	60	6	EFO_0004838
Disease	intestinal cancer (implicated_via_orthology)	PTPN2 FRK	1.94e-03	32	60	2	DOID:10155 (implicated_via_orthology)
Disease	Large cell carcinoma of lung	ATR NTRK3	1.94e-03	32	60	2	C0345958

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDWDLKVMLPGQCQY	ERI3	246	O43414
DPNCEMQKWSVNGVY	ASH1L	2226	Q9NR48
MWISKQEYEEGGKQC	ACTL6B	406	O94805
KCMVEWSKDQYVNPN	ARFGEF1	621	Q9Y6D6
GKVVPMNCWGVYQAV	CCDC154	611	A6NI56
VYQEGCMEKVQAWLQ	CD82	211	P27701
MITNTNNGWKYFCPI	CPXCR1	266	Q8N123
PGQEMQWDCINPKYR	CPNE6	256	O95741
NWKQELVNQKDCPYM	PITPNA	176	Q00169
PDEVYQLMRKCWEFQ	JAK1	1121	P23458
VKCAQYWPTDDQEML	PTPN2	121	P17706
VNNQYCKKVIGGMVW	PTPN3	336	P26045
VQYQWFKMNKEIPNG	MALT1	156	Q9UDY8
PKEVYDVMLGCWQRE	NTRK3	796	Q16288
PCMQKWSLEYIQEIA	KDM8	216	Q8N371
MNPIVYCVKTRQIWE	OR51A7	286	Q8NH64
DWIKPENFQKGCQMY	ENPEP	491	Q07075
QQSPEQWQKMYGRCS	KCNT2	471	Q6UVM3
QGCKMNNVNVVYTPW	CCDC25	81	Q86WR0
KEVCPWMQTVYTQVR	PTPRQ	136	Q9UMZ3
GMWDKYNEPLLQSVC	FJX1	351	Q86VR8
CQWIRQKFETPGIMQ	OGDH	231	Q02218
NGMYDKNLNCVWIII	CUBN	3176	O60494
QFYNIMLECWNAEPK	FRK	461	P42685
NKRPDYNEMVGECWL	ATR	1911	Q13535
VMLVECYDPKGDQWN	KLHL14	536	Q9P2G3
MADQQLPYWVQCTKP	KDM1B	131	Q8NB78
MEGKQVQWECINPKY	CPNE4	256	Q96A23
CEQKMVDGTYWVDPN	COL27A1	1696	Q8IZC6
PQKKCQEYEMSLENW	GK5	501	Q6ZS86
KPETYCTQYGEWQMK	LAMB3	51	Q13751
VYWNQADKIPVMRGQ	DDHD1	276	Q8NEL9
LQCSIEMPNISYAWK	DDX21	641	Q9NR30
AVNNYCPWKIGKMET	CCDC198	231	Q9NVL8
CLSTKPNNQMYLGIW	DIPK1A	91	Q5T7M9
QVVNYTQGLWEKVMP	SLC19A2	311	O60779
NCYIFNWGMTEKALP	SCNN1B	271	P51168
YGIVMQRWKPFQQDV	MCM9	241	Q9NXL9
PEVFMQTGYNKLCDW	STK38	291	Q15208
QDQCWETYVGQEMLK	TMC3	496	Q7Z5M5
FKQVWDNALYCVMGP	SV2B	371	Q7L1I2
GQTNCWVRPDMKYIG	LARS1	301	Q9P2J5
QMEGPWCFTQNKNVR	ROR2	371	Q01974
EKQDWTERPQQVCMG	PLB1	91	Q6P1J6
LYNPEMASCIQWVDK	SPIC	121	Q8N5J4
LWCQMKTAGYPNVNI	SPTBN1	181	Q01082
CQPEELGKMQIWICQ	LINC01553	71	A4QN01
NPEMLKQWEYCGQPK	PTRH2	101	Q9Y3E5
MEKLHQCYWKSGEPQ	UBE3A	1	Q05086
QDVWNMIQKLYLQPG	TEP1	1101	Q99973
TTYWCQMFKIPVFQE	MOXD1	201	Q6UVY6
KQLPCWETVLGQEMY	TMC4	471	Q7Z404
QNGMVQEYKVWCLGN	ROBO1	806	Q9Y6N7
LWCQMKTAGYPHVNV	SPTB	181	P11277
WRIKNEPYQVVECAM	TTC17	236	Q96AE7
WCKYQMLQALTEAPG	TIRAP	156	P58753
VWKIMPNFRGYQQQD	USP3	246	Q9Y6I4
QSPEEMQGWINKINC	PSD3	881	Q9NYI0
CYWGKETLDMINPVQ	TIA1	281	P31483
QKLYPCWETQVGQEM	TMC7	481	Q7Z402
IPYNVINQSVWECIM	UNC79	611	Q9P2D8