| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | ABC-type transporter activity | 5.20e-08 | 49 | 83 | 6 | GO:0140359 | |
| GeneOntologyMolecularFunction | ATP hydrolysis activity | DMC1 ABCB9 ABCA12 MYO19 IGHMBP2 ATAD2B HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 2.72e-07 | 441 | 83 | 12 | GO:0016887 |
| GeneOntologyMolecularFunction | ribonucleoside triphosphate phosphatase activity | DMC1 ABCB9 RASA1 ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 3.45e-06 | 775 | 83 | 14 | GO:0017111 |
| GeneOntologyMolecularFunction | ATPase-coupled transmembrane transporter activity | 6.18e-06 | 109 | 83 | 6 | GO:0042626 | |
| GeneOntologyMolecularFunction | ATP-dependent activity | DMC1 ABCB9 ABCA12 MYO19 IGHMBP2 ATAD2B HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 8.47e-06 | 614 | 83 | 12 | GO:0140657 |
| GeneOntologyMolecularFunction | pyrophosphatase activity | DMC1 ABCB9 RASA1 ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 8.55e-06 | 839 | 83 | 14 | GO:0016462 |
| GeneOntologyMolecularFunction | hydrolase activity, acting on acid anhydrides | DMC1 ABCB9 RASA1 ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 8.67e-06 | 840 | 83 | 14 | GO:0016817 |
| GeneOntologyMolecularFunction | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | DMC1 ABCB9 RASA1 ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 8.67e-06 | 840 | 83 | 14 | GO:0016818 |
| GeneOntologyMolecularFunction | primary active transmembrane transporter activity | 9.86e-05 | 178 | 83 | 6 | GO:0015399 | |
| GeneOntologyMolecularFunction | structural constituent of nuclear pore | 1.49e-04 | 25 | 83 | 3 | GO:0017056 | |
| GeneOntologyMolecularFunction | heme transmembrane transporter activity | 6.03e-04 | 9 | 83 | 2 | GO:0015232 | |
| GeneOntologyMolecularFunction | ATPase-coupled inorganic anion transmembrane transporter activity | 7.52e-04 | 10 | 83 | 2 | GO:0043225 | |
| GeneOntologyMolecularFunction | acyltransferase activity | 1.38e-03 | 775 | 83 | 10 | GO:0016746 | |
| GeneOntologyMolecularFunction | ABC-type xenobiotic transporter activity | 1.73e-03 | 15 | 83 | 2 | GO:0008559 | |
| GeneOntologyMolecularFunction | efflux transmembrane transporter activity | 1.97e-03 | 16 | 83 | 2 | GO:0015562 | |
| GeneOntologyMolecularFunction | oligopeptide transmembrane transporter activity | 1.97e-03 | 16 | 83 | 2 | GO:0035673 | |
| GeneOntologyCellularComponent | nuclear pore inner ring | 4.77e-05 | 3 | 84 | 2 | GO:0044611 | |
| Domain | AAA+_ATPase | DMC1 ABCB9 ABCA12 IGHMBP2 ATAD2B HELZ2 ABCC5 ABCB6 ABCA7 ABCC6 | 7.22e-10 | 144 | 82 | 10 | IPR003593 |
| Domain | AAA | DMC1 ABCB9 ABCA12 IGHMBP2 ATAD2B HELZ2 ABCC5 ABCB6 ABCA7 ABCC6 | 7.22e-10 | 144 | 82 | 10 | SM00382 |
| Domain | ABC_transporter_CS | 2.75e-08 | 42 | 82 | 6 | IPR017871 | |
| Domain | ABC_tran | 6.30e-08 | 48 | 82 | 6 | PF00005 | |
| Domain | ABC_TRANSPORTER_2 | 6.30e-08 | 48 | 82 | 6 | PS50893 | |
| Domain | ABC_TRANSPORTER_1 | 7.15e-08 | 49 | 82 | 6 | PS00211 | |
| Domain | ABC_transporter-like | 8.10e-08 | 50 | 82 | 6 | IPR003439 | |
| Domain | ABC_membrane | 3.43e-06 | 24 | 82 | 4 | PF00664 | |
| Domain | ABC_TM1F | 6.52e-06 | 28 | 82 | 4 | PS50929 | |
| Domain | ABC1_TM_dom | 6.52e-06 | 28 | 82 | 4 | IPR011527 | |
| Domain | ARM-type_fold | 1.76e-05 | 339 | 82 | 9 | IPR016024 | |
| Domain | P-loop_NTPase | DMC1 ABCB9 CIITA ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 KIF14 ABCC5 ABCB6 ABCA7 ABCC6 | 1.76e-05 | 848 | 82 | 14 | IPR027417 |
| Domain | - | DMC1 ABCB9 ABCA12 MYO19 IGHMBP2 ATAD2B LRRK2 HELZ2 ABCC5 ABCB6 ABCA7 ABCC6 | 9.60e-05 | 746 | 82 | 12 | 3.40.50.300 |
| Domain | ARM-like | 1.21e-03 | 270 | 82 | 6 | IPR011989 | |
| Domain | ABC_A | 1.22e-03 | 12 | 82 | 2 | IPR026082 | |
| Domain | - | 2.88e-03 | 321 | 82 | 6 | 3.80.10.10 | |
| Domain | - | 2.95e-03 | 222 | 82 | 5 | 1.25.10.10 | |
| Domain | L_dom-like | 3.21e-03 | 328 | 82 | 6 | IPR032675 | |
| Domain | C2_dom | 5.89e-03 | 164 | 82 | 4 | IPR000008 | |
| Pathway | KEGG_ABC_TRANSPORTERS | 2.86e-08 | 44 | 60 | 6 | M11911 | |
| Pathway | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | 1.94e-07 | 99 | 60 | 7 | MM14986 | |
| Pathway | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | 2.54e-07 | 103 | 60 | 7 | M758 | |
| Pathway | REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS | 9.63e-06 | 177 | 60 | 7 | M27476 | |
| Pathway | REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION | 1.39e-04 | 24 | 60 | 3 | MM15658 | |
| Pathway | REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION | 1.99e-04 | 27 | 60 | 3 | M29807 | |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | 2.20e-04 | 70 | 60 | 4 | MM14984 | |
| Pathway | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | 2.33e-04 | 131 | 60 | 5 | M5283 | |
| Pathway | KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA | 2.74e-04 | 30 | 60 | 3 | M47752 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS | 3.18e-04 | 77 | 60 | 4 | M27226 | |
| Pathway | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | CUL5 PREB QSOX1 DPH1 MAN1A2 BRCA1 NFE2L2 NUP133 NCOA1 PSMD3 PPP6R1 NUP188 ST8SIA4 FBXL3 TBC1D20 NUP205 | 3.26e-04 | 1475 | 60 | 16 | M19806 |
| Pathway | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | 3.33e-04 | 32 | 60 | 3 | M29579 | |
| Pathway | REACTOME_ABC_TRANSPORTER_DISORDERS | 3.34e-04 | 78 | 60 | 4 | M27473 | |
| Pathway | REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS | 3.65e-04 | 33 | 60 | 3 | M27016 | |
| Pathway | REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN | 3.99e-04 | 34 | 60 | 3 | M27041 | |
| Pathway | REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS | 4.35e-04 | 35 | 60 | 3 | M27320 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS | 4.44e-04 | 84 | 60 | 4 | MM14929 | |
| Pathway | REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA | 4.74e-04 | 36 | 60 | 3 | M26974 | |
| Pathway | REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY | 4.74e-04 | 36 | 60 | 3 | M27245 | |
| Pathway | BIOCARTA_BARD1_PATHWAY | 4.91e-04 | 8 | 60 | 2 | M22050 | |
| Pathway | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | 5.14e-04 | 37 | 60 | 3 | M1029 | |
| Pathway | REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS | 5.14e-04 | 37 | 60 | 3 | M27038 | |
| Pathway | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | PREB QSOX1 DPH1 MAN1A2 BRCA1 NFE2L2 NUP133 NCOA1 PSMD3 PPP6R1 NUP188 ST8SIA4 FBXL3 TBC1D20 NUP205 | 5.52e-04 | 1389 | 60 | 15 | MM15307 |
| Pathway | REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS | 6.01e-04 | 39 | 60 | 3 | M27238 | |
| Pathway | REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY | 6.47e-04 | 40 | 60 | 3 | MM14945 | |
| Pathway | REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS | 6.96e-04 | 41 | 60 | 3 | M29574 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS | 6.96e-04 | 41 | 60 | 3 | MM15200 | |
| Pathway | REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS | 7.48e-04 | 42 | 60 | 3 | MM15039 | |
| Pathway | REACTOME_SUMOYLATION | 7.48e-04 | 169 | 60 | 5 | MM14919 | |
| Pathway | REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA | 8.01e-04 | 43 | 60 | 3 | MM14609 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS | 8.01e-04 | 43 | 60 | 3 | M26975 | |
| Pathway | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | 8.57e-04 | 44 | 60 | 3 | M109 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS | 9.77e-04 | 46 | 60 | 3 | M27397 | |
| Pathway | REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS | 1.04e-03 | 47 | 60 | 3 | M27395 | |
| Pathway | REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS | 1.04e-03 | 47 | 60 | 3 | MM14939 | |
| Pathway | REACTOME_HEME_SIGNALING | 1.18e-03 | 49 | 60 | 3 | M41832 | |
| Pathway | REACTOME_GENE_SILENCING_BY_RNA | 1.18e-03 | 49 | 60 | 3 | MM14837 | |
| Pathway | REACTOME_SUMOYLATION | 1.24e-03 | 189 | 60 | 5 | M27214 | |
| Pathway | REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS | 1.25e-03 | 50 | 60 | 3 | MM14610 | |
| Pathway | REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS | 1.32e-03 | 51 | 60 | 3 | MM15151 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN | 1.48e-03 | 53 | 60 | 3 | M27212 | |
| Pathway | REACTOME_SNRNP_ASSEMBLY | 1.56e-03 | 54 | 60 | 3 | M29594 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN | 1.64e-03 | 55 | 60 | 3 | MM14917 | |
| Pathway | BIOCARTA_AMAN_PATHWAY | 1.81e-03 | 15 | 60 | 2 | M22009 | |
| Pathway | REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS | 1.92e-03 | 58 | 60 | 3 | MM15149 | |
| Pathway | REACTOME_SNRNP_ASSEMBLY | 1.92e-03 | 58 | 60 | 3 | MM14736 | |
| Pathway | REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 1.96e-03 | 210 | 60 | 5 | M41836 | |
| Pathway | REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS | 2.01e-03 | 59 | 60 | 3 | M27606 | |
| Pathway | KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR | 2.06e-03 | 16 | 60 | 2 | M47855 | |
| Pathway | REACTOME_CYTOPROTECTION_BY_HMOX1 | 2.11e-03 | 60 | 60 | 3 | M41830 | |
| Pathway | REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | 2.33e-03 | 17 | 60 | 2 | MM14552 | |
| Pathway | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA | 2.61e-03 | 18 | 60 | 2 | MM15034 | |
| Pathway | REACTOME_RORA_ACTIVATES_GENE_EXPRESSION | 2.61e-03 | 18 | 60 | 2 | M26942 | |
| Pathway | REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | 2.61e-03 | 18 | 60 | 2 | M524 | |
| Pathway | REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS | 2.65e-03 | 65 | 60 | 3 | MM15147 | |
| Pathway | BIOCARTA_ATRBRCA_PATHWAY | 2.91e-03 | 19 | 60 | 2 | MM1478 | |
| Pathway | REACTOME_HIV_INFECTION | 2.97e-03 | 231 | 60 | 5 | M12469 | |
| Pathway | REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY | 3.02e-03 | 68 | 60 | 3 | MM14921 | |
| Pathway | REACTOME_COPII_MEDIATED_VESICLE_TRANSPORT | 3.15e-03 | 69 | 60 | 3 | M27113 | |
| Pathway | REACTOME_CIRCADIAN_CLOCK | 3.28e-03 | 70 | 60 | 3 | M938 | |
| Pathway | REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS | 3.41e-03 | 71 | 60 | 3 | M27394 | |
| Pubmed | 1.97e-09 | 22 | 85 | 5 | 8894702 | ||
| Pubmed | Nrf2 is associated with the regulation of basal transcription activity of the BRCA1 gene. | 5.90e-06 | 2 | 85 | 2 | 23353771 | |
| Pubmed | Loss of expression of FANCD2 protein in sporadic and hereditary breast cancer. | 5.90e-06 | 2 | 85 | 2 | 17333336 | |
| Pubmed | Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways. | 5.90e-06 | 2 | 85 | 2 | 12933903 | |
| Pubmed | 5.90e-06 | 2 | 85 | 2 | 35512617 | ||
| Pubmed | Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. | 5.90e-06 | 2 | 85 | 2 | 11239454 | |
| Pubmed | 5.90e-06 | 2 | 85 | 2 | 21919919 | ||
| Pubmed | 8.21e-06 | 193 | 85 | 6 | 19343046 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 37674036 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 27373334 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 34103686 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 19671671 | ||
| Pubmed | Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis. | 1.77e-05 | 3 | 85 | 2 | 28028237 | |
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 12887909 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 34238051 | ||
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 33770521 | ||
| Pubmed | S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. | 1.77e-05 | 3 | 85 | 2 | 12239151 | |
| Pubmed | 1.77e-05 | 3 | 85 | 2 | 27264184 | ||
| Pubmed | Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. | 2.41e-05 | 23 | 85 | 3 | 10708515 | |
| Pubmed | 3.53e-05 | 4 | 85 | 2 | 26385482 | ||
| Pubmed | Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway. | 3.53e-05 | 4 | 85 | 2 | 24567396 | |
| Pubmed | 3.53e-05 | 4 | 85 | 2 | 21203397 | ||
| Pubmed | BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival. | 3.53e-05 | 4 | 85 | 2 | 23857982 | |
| Pubmed | 3.53e-05 | 4 | 85 | 2 | 24708616 | ||
| Pubmed | 3.53e-05 | 250 | 85 | 6 | 33536335 | ||
| Pubmed | Probing nuclear pore complex architecture with proximity-dependent biotinylation. | 3.92e-05 | 77 | 85 | 4 | 24927568 | |
| Pubmed | Integrated structural analysis of the human nuclear pore complex scaffold. | 5.45e-05 | 30 | 85 | 3 | 24315095 | |
| Pubmed | 5.45e-05 | 30 | 85 | 3 | 27016207 | ||
| Pubmed | 5.87e-05 | 5 | 85 | 2 | 17563742 | ||
| Pubmed | 5.87e-05 | 5 | 85 | 2 | 25652403 | ||
| Pubmed | BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. | 5.87e-05 | 5 | 85 | 2 | 22445484 | |
| Pubmed | 5.87e-05 | 5 | 85 | 2 | 30733286 | ||
| Pubmed | 5.87e-05 | 5 | 85 | 2 | 9838122 | ||
| Pubmed | 5.87e-05 | 5 | 85 | 2 | 10527800 | ||
| Pubmed | 7.29e-05 | 33 | 85 | 3 | 19714462 | ||
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | C2CD3 ZNF516 HECTD4 HELZ2 C19orf44 FRMD8 ZER1 PPP6R1 NUP188 FHIP1B ABCA7 | 7.89e-05 | 1105 | 85 | 11 | 35748872 |
| Pubmed | HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways. | 7.98e-05 | 571 | 85 | 8 | 37167062 | |
| Pubmed | 8.80e-05 | 6 | 85 | 2 | 24966277 | ||
| Pubmed | 8.80e-05 | 6 | 85 | 2 | 35679425 | ||
| Pubmed | ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway. | 8.80e-05 | 6 | 85 | 2 | 22258451 | |
| Pubmed | 8.80e-05 | 6 | 85 | 2 | 37725982 | ||
| Pubmed | 8.80e-05 | 6 | 85 | 2 | 22988097 | ||
| Pubmed | 1.18e-04 | 102 | 85 | 4 | 11214970 | ||
| Pubmed | Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. | 1.23e-04 | 7 | 85 | 2 | 26878725 | |
| Pubmed | Anthracyclines induce DNA damage response-mediated protection against severe sepsis. | 1.23e-04 | 7 | 85 | 2 | 24184056 | |
| Pubmed | BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells. | 1.23e-04 | 7 | 85 | 2 | 16860316 | |
| Pubmed | 1.23e-04 | 7 | 85 | 2 | 18663141 | ||
| Pubmed | 1.23e-04 | 7 | 85 | 2 | 22549958 | ||
| Pubmed | PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. | 1.23e-04 | 7 | 85 | 2 | 22331464 | |
| Pubmed | 1.23e-04 | 7 | 85 | 2 | 12913077 | ||
| Pubmed | 1.30e-04 | 40 | 85 | 3 | 37516964 | ||
| Pubmed | SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice. | 1.64e-04 | 8 | 85 | 2 | 30393076 | |
| Pubmed | 1.64e-04 | 8 | 85 | 2 | 24293640 | ||
| Pubmed | 1.64e-04 | 8 | 85 | 2 | 15802388 | ||
| Pubmed | γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons. | 1.64e-04 | 8 | 85 | 2 | 37028432 | |
| Pubmed | ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis. | 1.64e-04 | 8 | 85 | 2 | 32051414 | |
| Pubmed | Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin. | 2.10e-04 | 9 | 85 | 2 | 32092106 | |
| Pubmed | Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes. | 2.10e-04 | 9 | 85 | 2 | 8530078 | |
| Pubmed | Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice. | 2.62e-04 | 10 | 85 | 2 | 35648791 | |
| Pubmed | Cdk12 is essential for embryonic development and the maintenance of genomic stability. | 2.62e-04 | 10 | 85 | 2 | 26658019 | |
| Pubmed | 3.20e-04 | 11 | 85 | 2 | 12607005 | ||
| Pubmed | 3.83e-04 | 12 | 85 | 2 | 25011556 | ||
| Pubmed | Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation. | 3.83e-04 | 12 | 85 | 2 | 35512830 | |
| Pubmed | 3.83e-04 | 12 | 85 | 2 | 31453335 | ||
| Pubmed | Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. | 3.83e-04 | 12 | 85 | 2 | 20551173 | |
| Pubmed | 3.83e-04 | 12 | 85 | 2 | 25256039 | ||
| Pubmed | 3.83e-04 | 12 | 85 | 2 | 12189208 | ||
| Pubmed | CUL5 FANCD2 DPH1 ARHGEF28 NCOA1 VPS54 NUP188 HSD11B1L KAT14 TBC1D20 NUP205 | 3.84e-04 | 1327 | 85 | 11 | 32694731 | |
| Pubmed | FANCD2 BRCA1 MAP1A ABCA12 TIGD5 PPP6R1 NUP188 PLEKHN1 ABCA7 KAT14 | 3.94e-04 | 1116 | 85 | 10 | 31753913 | |
| Pubmed | Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. | 4.29e-04 | 732 | 85 | 8 | 34732716 | |
| Pubmed | 4.52e-04 | 13 | 85 | 2 | 24252804 | ||
| Pubmed | The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA. | 4.69e-04 | 262 | 85 | 5 | 36880596 | |
| Pubmed | 5.27e-04 | 14 | 85 | 2 | 19755105 | ||
| Pubmed | A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing. | 5.27e-04 | 14 | 85 | 2 | 8114702 | |
| Pubmed | 5.27e-04 | 14 | 85 | 2 | 30995416 | ||
| Pubmed | Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198. | 5.27e-04 | 14 | 85 | 2 | 1348494 | |
| Pubmed | PREB DNAJC13 MAN1A2 IGHMBP2 HELZ2 NUP133 KIF14 PSMD3 NUP188 NUP205 | 5.61e-04 | 1168 | 85 | 10 | 19946888 | |
| Pubmed | 6.07e-04 | 15 | 85 | 2 | 19536649 | ||
| Pubmed | DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon. | 6.07e-04 | 15 | 85 | 2 | 37541195 | |
| Pubmed | 6.07e-04 | 15 | 85 | 2 | 38684656 | ||
| Pubmed | Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex. | 6.07e-04 | 15 | 85 | 2 | 27073218 | |
| Pubmed | A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling. | 6.27e-04 | 974 | 85 | 9 | 28675297 | |
| Pubmed | 6.93e-04 | 16 | 85 | 2 | 27760317 | ||
| Pubmed | Physical and linkage mapping of human chromosome 17 loci to dog chromosomes 9 and 5. | 6.93e-04 | 16 | 85 | 2 | 9177778 | |
| Pubmed | C2CD3 BRCA1 ABCB9 SYNE1 ABCC5 PSMD3 OR10G9 OR10G8 OR10G7 NUP205 OR10G4 | 7.66e-04 | 1442 | 85 | 11 | 35575683 | |
| Pubmed | 7.84e-04 | 17 | 85 | 2 | 10668806 | ||
| Pubmed | 8.38e-04 | 75 | 85 | 3 | 20644561 | ||
| Pubmed | 8.80e-04 | 18 | 85 | 2 | 18187417 | ||
| Pubmed | C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway. | 9.83e-04 | 19 | 85 | 2 | 38915692 | |
| Pubmed | Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. | 9.83e-04 | 19 | 85 | 2 | 21478856 | |
| Pubmed | Genomewide discovery and classification of candidate ovarian fertility genes in the mouse. | 9.83e-04 | 19 | 85 | 2 | 17660561 | |
| Pubmed | 1.08e-03 | 650 | 85 | 7 | 38777146 | ||
| Pubmed | 1.09e-03 | 20 | 85 | 2 | 36334588 | ||
| Pubmed | 1.09e-03 | 20 | 85 | 2 | 23791195 | ||
| Pubmed | Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. | 1.17e-03 | 321 | 85 | 5 | 32098917 | |
| Pubmed | ETAA1 acts at stalled replication forks to maintain genome integrity. | 1.20e-03 | 21 | 85 | 2 | 27723720 | |
| Pubmed | The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations. | 1.20e-03 | 21 | 85 | 2 | 19578876 | |
| Pubmed | 1.32e-03 | 22 | 85 | 2 | 12812986 | ||
| Pubmed | Negative modulation of androgen receptor transcriptional activity by Daxx. | 1.32e-03 | 22 | 85 | 2 | 15572661 | |
| Pubmed | 1.35e-03 | 332 | 85 | 5 | 25693804 | ||
| Interaction | AHR interactions | 1.21e-06 | 132 | 83 | 7 | int:AHR | |
| Interaction | TMOD3 interactions | 7.21e-06 | 243 | 83 | 8 | int:TMOD3 | |
| GeneFamily | Olfactory receptors, family 10 | 7.70e-05 | 66 | 62 | 4 | 157 | |
| GeneFamily | Nucleoporins | 1.77e-04 | 32 | 62 | 3 | 1051 | |
| GeneFamily | UPF1 like RNA helicases | 6.24e-04 | 11 | 62 | 2 | 1169 | |
| GeneFamily | ATP binding cassette subfamily B | 6.24e-04 | 11 | 62 | 2 | 806 | |
| GeneFamily | ATP binding cassette subfamily C | 8.81e-04 | 13 | 62 | 2 | 807 | |
| GeneFamily | ATP binding cassette subfamily A | 1.03e-03 | 14 | 62 | 2 | 805 | |
| GeneFamily | Ring finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex | 2.11e-03 | 20 | 62 | 2 | 548 | |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | 6.76e-03 | 36 | 62 | 2 | 823 | |
| CoexpressionAtlas | dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000 | 4.57e-05 | 258 | 78 | 7 | gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000 | |
| CoexpressionAtlas | dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000 | 5.54e-05 | 266 | 78 | 7 | gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000 | |
| Drug | PF-01378883-00 [351320-41-7]; Down 200; 10uM; MCF7; HT_HG-U133A | 8.03e-06 | 198 | 83 | 7 | 6363_DN | |
| Drug | Esculetin [305-01-1]; Down 200; 22.4uM; MCF7; HT_HG-U133A | 8.30e-06 | 199 | 83 | 7 | 6499_DN | |
| Drug | docetaxel | 9.26e-06 | 133 | 83 | 6 | ctd:C067311 | |
| Drug | harmol sulfate | 1.30e-05 | 13 | 83 | 3 | CID005488302 | |
| Disease | Keratosis Blennorrhagica | 7.59e-05 | 5 | 82 | 2 | C0022594 | |
| Disease | Keratosis | 7.59e-05 | 5 | 82 | 2 | C0022593 | |
| Disease | Keratoma | 7.59e-05 | 5 | 82 | 2 | C0086501 | |
| Disease | obsolete_red blood cell distribution width | DNAJC13 MYO19 ATAD2B ZNF516 HECTD4 HELZ2 ABCC5 PKD2L1 ABCB6 TIGD5 STKLD1 HSD11B1L ABCA7 | 8.36e-05 | 1347 | 82 | 13 | EFO_0005192 |
| Disease | monocyte percentage of leukocytes | 1.96e-04 | 731 | 82 | 9 | EFO_0007989 | |
| Disease | Alzheimer disease | 2.11e-04 | 8 | 82 | 2 | cv:C0002395 | |
| Disease | Fanconi anemia (is_implicated_in) | 3.38e-04 | 10 | 82 | 2 | DOID:13636 (is_implicated_in) | |
| Disease | neutrophil count, basophil count | 4.09e-04 | 224 | 82 | 5 | EFO_0004833, EFO_0005090 | |
| Disease | Pancreatic Ductal Adenocarcinoma | 4.13e-04 | 11 | 82 | 2 | C1335302 | |
| Disease | Chromosome Breaks | 6.79e-04 | 14 | 82 | 2 | C0333704 | |
| Disease | Chromosome Breakage | 6.79e-04 | 14 | 82 | 2 | C0376628 | |
| Disease | Colorectal Neoplasms | 1.06e-03 | 277 | 82 | 5 | C0009404 | |
| Disease | myeloid white cell count | 1.17e-03 | 937 | 82 | 9 | EFO_0007988 | |
| Disease | neutrophil count | MPO DNAJC13 BRCA1 TTC39C ZNF516 HECTD4 NCOA1 ABCC5 PSMD3 ABCA7 TENT5B | 1.51e-03 | 1382 | 82 | 11 | EFO_0004833 |
| Disease | neutrophil-to-lymphocyte ratio | 1.79e-03 | 185 | 82 | 4 | EFO_0008447 | |
| Disease | Fanconi Anemia | 2.20e-03 | 25 | 82 | 2 | C0015625 | |
| Disease | basophil count | 2.29e-03 | 483 | 82 | 6 | EFO_0005090 | |
| Disease | Acute monocytic leukemia | 2.37e-03 | 26 | 82 | 2 | C0023465 | |
| Disease | myeloperoxidase measurement | 2.37e-03 | 26 | 82 | 2 | EFO_0005243 | |
| Disease | chronic obstructive pulmonary disease (biomarker_via_orthology) | 2.75e-03 | 28 | 82 | 2 | DOID:3083 (biomarker_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LERLLHSTHIRVLAF | 331 | Q0P6H9 | |
| LHLLHALSLVTDVSR | 11 | P58513 | |
| IDRDSTLRRLHHIQI | 186 | Q76B58 | |
| AHLTRRLILDISADS | 456 | Q93034 | |
| HLLLLSHLLRLEHSA | 406 | O94812 | |
| TLLRDRPLLLSHSHS | 596 | P33076 | |
| NIVTLHDLIHTDRSL | 201 | Q07002 | |
| TARTIILSTHHLDEA | 1526 | Q86UK0 | |
| TSRRVELLIFSHLHE | 341 | Q9NP58 | |
| RLGSHLVLTAHTEAL | 51 | Q7Z5J1 | |
| HILAHASTTRISLRK | 291 | Q14565 | |
| DIRIDTTHLLDSLRL | 156 | Q9BZG8 | |
| REGRTLILSTHHLDE | 986 | Q8IZY2 | |
| IRIIETLDLHSSLHQ | 491 | Q6ZS30 | |
| HSRTDLSRDLAALHE | 986 | P20936 | |
| LRERLIDALESHHDT | 146 | O00391 | |
| HETRIHILNLLITSL | 981 | Q92621 | |
| SLEVSSHRESLLHLA | 156 | Q8N1W1 | |
| LRFLLLHRHDTHTIL | 371 | Q8N612 | |
| HHSRLSDLVNTAILI | 656 | Q8WUM0 | |
| HDHRITSRINLIDLA | 591 | Q15058 | |
| LLILLVIRVDSHLHT | 41 | Q8NGN6 | |
| LLILLVIRVDSHLHT | 41 | Q8NGN3 | |
| VRHLDRIDSVLLTHI | 76 | P78559 | |
| SLVHRLFTILHLEES | 166 | Q9NWR8 | |
| ASTSHEHDLRLLRLR | 101 | Q9UKR0 | |
| ILLERHRLIHVTSSA | 951 | Q96H55 | |
| SLSAHELHRAVREVL | 51 | Q9BZ67 | |
| ALLHTLERFSVHRLD | 786 | Q9ULI0 | |
| HTLLLREHNRLATEL | 416 | P05164 | |
| HSSRLEAHLTRDELR | 446 | Q16236 | |
| HLSSLISRHDDEATR | 6 | Q9H8E8 | |
| GERHSLLLLTNHRVL | 31 | Q8IVU3 | |
| LTRTLQHRIALHVAD | 1966 | Q5S007 | |
| LLILLVIRVDSHLHT | 41 | Q8NGN5 | |
| SDHIRLSDLIAARIL | 451 | Q6NUT2 | |
| LVFHLLAELLRTVHT | 2751 | Q9Y4D8 | |
| SVLDHSLESLIHRLR | 26 | Q9BUE0 | |
| DRILVAHDIHTKTRL | 291 | Q96BW5 | |
| ILLAILRIHSASGRH | 236 | Q8NGQ1 | |
| HLRLQRTLHSIDLEI | 571 | O15440 | |
| ELQVLHDISSLLSRH | 186 | O75787 | |
| LRRKSSTRHIHALEL | 611 | P38398 | |
| ALRVHVVLSSLSSHL | 1551 | Q4AC94 | |
| LLTLRHLHSVLEELR | 56 | A1L168 | |
| LLALSSEKHVRLEHL | 241 | Q9UKT7 | |
| QASRHLHASLLRSLD | 606 | Q9H6X5 | |
| LRSLLQHSLSLLRAH | 501 | Q6NUI2 | |
| LELSALVSKRHHEIL | 226 | P78329 | |
| DLLTLAHLHVSRATV | 941 | O75165 | |
| HHRATLRLSEKFILL | 26 | O60476 | |
| LHHLSRLRDLVDDTN | 351 | Q8IYD9 | |
| VARARAAEHTLLHRL | 706 | Q9BYK8 | |
| GIHLTRLRHDEIITL | 101 | Q9C0E4 | |
| SLLETFQLDTRLLHH | 1326 | Q9BXW9 | |
| IRTDTFKHLRHLEIL | 101 | Q9NT99 | |
| LLILLVIRVDSHLHT | 41 | Q8NGN4 | |
| DHTFHLELEAARLLR | 316 | Q6ZW31 | |
| LSKLHETLRTHTRLV | 151 | Q9UQF0 | |
| HLDLTQLHRLSLESS | 426 | Q494U1 | |
| HTRALHRLIAKSREL | 2786 | Q8NF91 | |
| AHVGLHTLRSRISII | 1331 | O95255 | |
| SSLTERHKILHRLLQ | 681 | Q15788 | |
| VLDRRRTLNISHDLH | 111 | Q92187 | |
| EALEHLRHRVIATRS | 256 | Q96A09 | |
| VFSHLDRSLLEDIRH | 26 | Q9NP78 | |
| HVRLHALDTRVVELT | 126 | Q9Y240 | |
| SRKHFRHLDLSELIL | 131 | Q16620 | |
| LDRVRTADHHQLRSL | 661 | Q9Y446 | |
| RLSASLLHSHDTETR | 56 | Q9HCU5 | |
| SNRLSILDRLLHTHP | 81 | Q8WYP3 | |
| REESLLSHIERDHIT | 211 | Q92618 | |
| HKLRHLDISRDRLSS | 246 | Q7Z7L7 | |
| LHARLRTATLRHDAD | 231 | O43242 | |
| LEHILEHLNSSLESR | 461 | Q8NE28 | |
| LTAHSSVARHLLRDL | 461 | P38935 | |
| SRTIFHDITRLHLDD | 1091 | Q9H5I5 | |
| HFTEATLHLLLTLAR | 1331 | Q5SRE5 | |
| ILELHIHRLRYLSSI | 371 | Q9P0L9 | |
| DLHTSSHLDTLLERE | 6 | Q9UPN7 | |
| VIHHDRARLLAALLS | 336 | Q9H892 | |
| LATSLVEKLSTHHLR | 161 | Q96BZ9 | |
| LHVRIHAALASLREL | 566 | Q8N584 | |
| HSRVLSDLTHLAALA | 506 | Q53EQ6 | |
| ESSYHLLISRLDLHI | 321 | Q6BDS2 | |
| RTLLHTHDKSRTDLE | 146 | Q9P1Q0 | |
| RVLSKLLRDSHVLHS | 31 | P40225 |