Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessvesicle cargo loading

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 CTAGE4

3.86e-1236537GO:0035459
GeneOntologyBiologicalProcessendoplasmic reticulum to Golgi vesicle-mediated transport

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 TRAPPC8 CTAGE4

6.90e-09159538GO:0006888
GeneOntologyBiologicalProcessGolgi vesicle transport

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 TRAPPC8 CTAGE4

2.28e-06339538GO:0048193
GeneOntologyBiologicalProcessintracellular transport

CTAGE9 SETD2 ABCA2 PTPN14 MIA2 GLI3 SEC24A IGHM CTAGE8 CTAGE15 CTAGE6 TRAPPC8 CTAGE4

7.91e-0514965313GO:0046907
GeneOntologyBiologicalProcessneural tube development

SETD2 GLI3 CECR2 DVL3 PROX1

1.68e-04202535GO:0021915
GeneOntologyBiologicalProcesslipid homeostasis

CTAGE9 ABCA2 MIA2 SEC24A CTAGE8

2.06e-04211535GO:0055088
GeneOntologyBiologicalProcessprotein secretion

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 CTAGE4

2.16e-04480537GO:0009306
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 CTAGE4

2.25e-04483537GO:0035592
GeneOntologyBiologicalProcessprotein localization to extracellular region

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 CTAGE4

2.45e-04490537GO:0071692
GeneOntologyBiologicalProcesstriglyceride homeostasis

CTAGE9 MIA2 CTAGE8

2.88e-0450533GO:0070328
GeneOntologyBiologicalProcesscholesterol homeostasis

CTAGE9 MIA2 SEC24A CTAGE8

2.90e-04124534GO:0042632
GeneOntologyBiologicalProcesssterol homeostasis

CTAGE9 MIA2 SEC24A CTAGE8

2.99e-04125534GO:0055092
GeneOntologyBiologicalProcessacylglycerol homeostasis

CTAGE9 MIA2 CTAGE8

3.06e-0451533GO:0055090
GeneOntologyCellularComponentendoplasmic reticulum exit site

CTAGE9 MIA2 SEC24A CTAGE8 CTAGE15 CTAGE6 CTAGE4

1.12e-1142537GO:0070971
MousePhenodecreased circulating VLDL triglyceride level

CTAGE9 MIA2 CTAGE8

1.89e-0519393MP:0003976
DomainBAT2_N

PRRC2C PRRC2A

1.86e-053472PF07001
DomainBAT2_N

PRRC2C PRRC2A

1.86e-053472IPR009738
DomainPRRC2

PRRC2C PRRC2A

1.86e-053472IPR033184
DomainNeurogenic_DUF

NEUROD2 NEUROD6

3.71e-054472IPR022575
DomainNeuro_bHLH

NEUROD2 NEUROD6

3.71e-054472PF12533
DomainTF_bHLH_NeuroD

NEUROD2 NEUROD6

3.71e-054472IPR016637
Domainzf-CCHC

ZCCHC8 ZCCHC2

1.52e-0323472PF00098
Domain-

ZCCHC8 ZCCHC2

1.94e-03264724.10.60.10
DomainZINC_FINGER_C2H2_2

ZNF48 ZNF608 DPF3 GLI3 TRPS1 MECOM ZNF503

3.05e-03775477PS50157
DomainZINC_FINGER_C2H2_1

ZNF48 ZNF608 DPF3 GLI3 TRPS1 MECOM ZNF503

3.09e-03777477PS00028
DomainZF_CCHC

ZCCHC8 ZCCHC2

3.50e-0335472PS50158
DomainZnf_C2H2-like

ZNF48 ZNF608 DPF3 GLI3 TRPS1 MECOM ZNF503

3.53e-03796477IPR015880
DomainZnf_C2H2

ZNF48 ZNF608 DPF3 GLI3 TRPS1 MECOM ZNF503

3.76e-03805477IPR007087
DomainZnF_C2H2

ZNF48 ZNF608 DPF3 GLI3 TRPS1 MECOM ZNF503

3.84e-03808477SM00355
DomainZnF_C2HC

ZCCHC8 ZCCHC2

8.46e-0355472SM00343
DomainZnf_CCHC

ZCCHC8 ZCCHC2

8.46e-0355472IPR001878
DomainUBA-like

UBAP2L CUEDC1

1.13e-0264472IPR009060
DomainHMG_box_dom

MIA2 PROX1

1.17e-0265472IPR009071
PathwayREACTOME_CARGO_CONCENTRATION_IN_THE_ER

CTAGE9 MIA2 SEC24A CTAGE8

1.57e-0636344MM15300
Pubmed

Human transcription factor protein interaction networks.

ZNF608 UBAP2L DPF3 PRRC2C GLI3 SEC24A TRPS1 ETV3 MECOM TNIP1 PABPC1L PAN3 LSM14B PRRC2A ZNF503

2.14e-091429531535140242
Pubmed

Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.

CTAGE9 MIA2 CTAGE8

1.34e-08453333718348
Pubmed

Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.

CTAGE9 MIA2 CTAGE8

1.34e-08453312586826
Pubmed

Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.

CTAGE9 MIA2 CTAGE8

1.34e-08453327311593
Pubmed

MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.

CTAGE9 MIA2 CTAGE8

1.34e-08453331244610
Pubmed

Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.

CTAGE9 MIA2 CTAGE8

1.34e-08453321807889
Pubmed

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

CTAGE9 MIA2 CTAGE8

3.33e-08553318630941
Pubmed

cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.

CTAGE9 MIA2 CTAGE4

3.33e-08553312839582
Pubmed

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

CTAGE9 MIA2 CTAGE8

3.33e-08553319131326
Pubmed

Characterization and expression pattern of the novel MIA homolog TANGO.

CTAGE9 MIA2 CTAGE8

3.33e-08553315183315
Pubmed

Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.

CTAGE9 MIA2 CTAGE8

3.33e-08553338439956
Pubmed

A tissue-specific atlas of mouse protein phosphorylation and expression.

CTAGE9 MIA2 CTAGE8

3.33e-08553321183079
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

SETD2 UBAP2L ZCCHC8 SEC24A NAF1 DVL3 ETV3 RNF216 TNIP1 PABPC1L PAN3 LSM14B

4.05e-081038531226673895
Pubmed

cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.

CTAGE9 MIA2 CTAGE8

1.16e-07753329133483
Pubmed

Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.

CTAGE9 MIA2 CTAGE8

2.79e-07953318342301
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

SETD2 PTPN14 ZNF608 ZCCHC8 DPF3 GLI3 CECR2 NAF1 TRPS1 MECOM PROX1

7.83e-071116531131753913
Pubmed

Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.

CTAGE9 MIA2 CTAGE8

9.45e-071353311839810
Pubmed

cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development.

CTAGE9 MIA2 CTAGE8

1.50e-061553330224460
Pubmed

Dynamic association and localization of human H/ACA RNP proteins.

NAF1 TNIP1

2.28e-06253217135485
Pubmed

Neuronal basic helix-loop-helix proteins (NEX, neuroD, NDRF): spatiotemporal expression and targeted disruption of the NEX gene in transgenic mice.

NEUROD2 NEUROD6

2.28e-0625329454850
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF608 ZCCHC8 TRPS1 DVL3 MECOM TNIP1 PROX1

3.30e-0641853734709266
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

UBAP2L ZCCHC8 PRRC2C NAF1 PAN3 TENM2 PRRC2A

6.34e-0646253731138677
Pubmed

SETD2 is essential for terminal differentiation of erythroblasts during fetal erythropoiesis.

SETD2 PROX1

6.83e-06353233743353
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

PTPN14 UBAP2L ZCCHC8 PRRC2C NAF1 PAN3 TRAPPC14 PRRC2A

8.19e-0667853830209976
Pubmed

Genetic mapping of four mouse bHLH genes related to Drosophila proneural gene atonal.

NEUROD2 NEUROD6

1.36e-0545328938455
Pubmed

Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb.

GLI3 ZNF503

1.36e-05453218351672
Pubmed

NeuroD factors regulate cell fate and neurite stratification in the developing retina.

NEUROD2 NEUROD6

1.36e-05453221593321
Pubmed

Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy.

GLI3 TRPS1

1.36e-05453231550480
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABCA2 NEUROD2 MIA2 ZCCHC8 TRPS1 DVL3 RNF216 NEUROD6 PRRC2A CUEDC1

2.10e-051285531035914814
Pubmed

Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy.

NEUROD6 PROX1

2.27e-05553210639171
Pubmed

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.

CTAGE9 MIA2 CTAGE8

2.30e-053653333230114
Pubmed

Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.

NEUROD2 EPHA3 PROX1

2.71e-053853338086370
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

SETD2 PTPN14 ZCCHC8 PRRC2C MECOM TNIP1 ZCCHC2

2.99e-0558853738580884
Pubmed

The phagosomal proteome in interferon-gamma-activated macrophages.

CTAGE9 MIA2 CTAGE8

3.17e-054053319144319
Pubmed

hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase.

NAF1 TNIP1

4.76e-05753216601202
Pubmed

A single-cell transcriptomic landscape of cadmium-hindered brain development in mice.

NEUROD2 NEUROD6

6.34e-05853239147853
Pubmed

A census of human transcription factors: function, expression and evolution.

NEUROD2 NFE2 GLI3 TRPS1 ETV3 NEUROD6 THAP7 PROX1

6.56e-0590853819274049
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

SETD2 ZCCHC8 GLI3 ETV3 MECOM

7.06e-0528253523667531
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

UBAP2L PRRC2C PRRC2A

7.84e-055453325631074
Pubmed

Survival of a Novel Subset of Midbrain Dopaminergic Neurons Projecting to the Lateral Septum Is Dependent on NeuroD Proteins.

NEUROD2 NEUROD6

8.15e-05953228130357
Pubmed

Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions.

NEUROD6 PROX1

1.02e-041053228945921
Pubmed

Neuropilin-2 regulates the development of selective cranial and sensory nerves and hippocampal mossy fiber projections.

NEUROD6 PROX1

1.02e-041053210707971
Pubmed

Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities.

NEUROD6 PROX1

1.02e-041053214715945
Pubmed

A novel cell migratory zone in the developing hippocampal formation.

NEUROD6 PROX1

1.02e-041053224771490
Pubmed

nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development.

NEUROD6 PROX1

1.24e-041153212834871
Pubmed

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.

GLI3 TRPS1

1.24e-041153219389374
Pubmed

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.

NEUROD6 PROX1

1.24e-041153233087478
Pubmed

The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.

GLI3 NEUROD6 PROX1

1.24e-046353322923088
Pubmed

SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.

SETD2 GLI3

1.49e-041253231911863
Pubmed

Pulmonary Fibrosis Predisposition Overview

ZCCHC8 NAF1

1.76e-041353220301408
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD2 PTPN14 UBAP2L PRRC2C TNIP1 PRRC2A

1.84e-0454953638280479
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF608 DPF3 TRPS1 MECOM ZNF503

1.96e-0435153538297188
Pubmed

Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice.

NEUROD2 PROX1

2.05e-041453233203851
Pubmed

bHLH gene expression in the Emx2-deficient dentate gyrus reveals defective granule cells and absence of migrating precursors.

NEUROD2 PROX1

2.05e-041453215084498
Pubmed

COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.

NEUROD2 NEUROD6

2.05e-041453221965613
Pubmed

Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.

NEUROD2 NEUROD6

2.05e-041453218160702
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

SETD2 UBAP2L CNTRL DVL3 TNIP1 ZCCHC2

2.05e-0456053621653829
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

C9orf152 PTPN14 DPF3 TRAPPC14 EPHA3 CUEDC1 ZNF503

2.59e-0483253736724073
Pubmed

An Early Cortical Progenitor-Specific Mechanism Regulates Thalamocortical Innervation.

NEUROD6 PROX1

2.70e-041653234193558
Pubmed

A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.

NFE2 MECOM

2.70e-041653220647008
Pubmed

Dyskeratosis Congenita and Related Telomere Biology Disorders

ZCCHC8 NAF1

2.70e-041653220301779
Pubmed

Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.

NFE2 MECOM

2.70e-041653215914564
Pubmed

Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets.

NFE2 PROX1

2.70e-041653226457609
Pubmed

A genomic atlas of mouse hypothalamic development.

GLI3 TENM2 EPHA3 PROX1

2.74e-0420553420436479
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

CTAGE9 MIA2 CNTRL CTAGE8

2.74e-0420553412040188
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MIA2 ZNF608 PRRC2C CNTRL CTAGE8 CTAGE15 PABPC1L CTAGE6 CTAGE4

3.01e-04144253935575683
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

NEUROD6 PROX1

3.05e-041753211683995
Pubmed

LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.

PRRC2C PRRC2A

3.05e-041753237072811
Pubmed

A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex.

NEUROD2 NEUROD6

3.05e-041753217694053
Pubmed

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

GLI3 EPHA3

3.05e-041753219168674
Pubmed

GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.

DVL3 NEUROD6

3.43e-041853225073924
Pubmed

Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity.

NEUROD6 PROX1

3.43e-041853235930666
Pubmed

Serological detection of cutaneous T-cell lymphoma-associated antigens.

MIA2 CTAGE4

3.43e-041853211149944
Pubmed

Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development.

NEUROD6 PROX1

3.43e-041853221991391
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

ZNF608 CECR2 TRPS1 MECOM ZNF503

3.50e-0439853535016035
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

SETD2 UBAP2L PRRC2C PRRC2A ZNF503

3.54e-0439953535987950
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

CNTRL MECOM TENM2

3.69e-049153322610502
Pubmed

A mega-analysis of genome-wide association studies for major depressive disorder.

TRPS1 DVL3

3.83e-041953222472876
Pubmed

Neurogenin 2 has an essential role in development of the dentate gyrus.

NEUROD6 PROX1

3.83e-041953218448566
Pubmed

Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala.

NEUROD2 NEUROD6

3.83e-041953233492553
Pubmed

Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.

GLI3 ZNF503

4.25e-042053216169709
Pubmed

The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.

UBAP2L PRRC2C PRRC2A

4.45e-049753337151849
Pubmed

Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.

NEUROD2 NEUROD6

4.70e-042153223303943
Pubmed

A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.

NEUROD2 NEUROD6

4.70e-042153218721803
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

UBAP2L PRRC2C PRRC2A

5.01e-0410153326949739
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SETD2 CECR2 ZCCHC2

5.16e-0410253311214970
Pubmed

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.

NEUROD2 PROX1

5.16e-042253219020049
Pubmed

PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA.

PRRC2C PRRC2A

5.16e-042253238507412
Pubmed

Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size.

NEUROD2 NEUROD6

5.16e-042253238697111
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZCCHC8 TRAPPC8 PROX1

5.31e-0410353332744500
Pubmed

The DNA sequence of human chromosome 7.

CTAGE9 GLI3 CTAGE8 RNF216 CTAGE4

5.57e-0444153512853948
Pubmed

FGF signalling generates ventral telencephalic cells independently of SHH.

GLI3 PROX1

5.65e-042353216818446
Pubmed

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb.

GLI3 ZNF503

5.65e-042353219783740
Pubmed

Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.

CTAGE9 MIA2 CTAGE8 TENM2

5.70e-042495349371744
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

PTPN14 UBAP2L PRRC2C NAF1 LSM14B PRRC2A ZNF503

6.52e-0497153733306668
Pubmed

T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.

GLI3 EPHA3

6.68e-042553227046536
Pubmed

HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3.

EPHA3 PROX1

6.68e-042553227518902
Pubmed

Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly.

GLI3 PROX1

6.68e-042553217468181
Pubmed

Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

NEUROD6 PROX1

6.68e-042553229311744
Pubmed

A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development.

GLI3 PROX1

6.68e-042553232840212
InteractionCTAGE1 interactions

MIA2 CTAGE8 CTAGE15 CTAGE6 CTAGE4

1.91e-1110505int:CTAGE1
InteractionFAM120C interactions

PTPN14 UBAP2L PRRC2C DVL3 PAN3 LSM14B PRRC2A

4.35e-07191507int:FAM120C
InteractionMIA2 interactions

MIA2 CTAGE8 CTAGE15 CTAGE6 CTAGE4

8.78e-06113505int:MIA2
InteractionYTHDF2 interactions

UBAP2L PRRC2C GLI3 PAN3 ZCCHC2 LSM14B PRRC2A

1.12e-05312507int:YTHDF2
InteractionSYNE3 interactions

PTPN14 MIA2 GLI3 SEC24A TNIP1 PAN3 COLGALT1 ZCCHC2

1.24e-05444508int:SYNE3
InteractionR3HDM2 interactions

UBAP2L PRRC2C PAN3 ZCCHC2 PRRC2A

1.67e-05129505int:R3HDM2
InteractionMEX3B interactions

UBAP2L PRRC2C DVL3 PAN3 LSM14B PRRC2A

1.77e-05222506int:MEX3B
InteractionCTAGE4 interactions

MIA2 CTAGE4

1.81e-053502int:CTAGE4
InteractionTNRC6C interactions

UBAP2L SEC24A TNIP1 PAN3 PRRC2A

2.32e-05138505int:TNRC6C
InteractionZCCHC2 interactions

UBAP2L ZCCHC2 PRRC2A

2.46e-0523503int:ZCCHC2
InteractionOTUD4 interactions

UBAP2L PRRC2C GLI3 NAF1 ZCCHC2 PRRC2A

2.50e-05236506int:OTUD4
InteractionDAZL interactions

UBAP2L PRRC2C ZCCHC2 LSM14B PRRC2A

2.94e-05145505int:DAZL
InteractionCPEB1 interactions

UBAP2L PRRC2C PAN3 LSM14B PRRC2A

3.04e-05146505int:CPEB1
InteractionYTHDF3 interactions

UBAP2L PRRC2C PAN3 ZCCHC2 LSM14B PRRC2A

3.15e-05246506int:YTHDF3
InteractionTLE3 interactions

SETD2 ZNF608 SEC24A CECR2 TRPS1 RNF216 ZNF503

3.73e-05376507int:TLE3
InteractionSOX6 interactions

PRRC2C TRPS1 MECOM PRRC2A ZNF503

4.30e-05157505int:SOX6
InteractionMKRN2 interactions

UBAP2L PRRC2C GLI3 PAN3 PRRC2A EPHA3 PROX1

4.33e-05385507int:MKRN2
InteractionSOX5 interactions

ZNF608 PRRC2C TRPS1 PRRC2A ZNF503

4.99e-05162505int:SOX5
InteractionCTAGE15 interactions

MIA2 CTAGE15

6.00e-055502int:CTAGE15
InteractionUNK interactions

UBAP2L PRRC2C SEC24A DVL3 TNIP1 TRAPPC8 PRRC2A

6.24e-05408507int:UNK
InteractionGSC interactions

ZNF608 TRPS1 MECOM ZNF503

6.41e-0587504int:GSC
InteractionTNRC6B interactions

UBAP2L GLI3 SEC24A CNTRL PAN3 PRRC2A

6.75e-05282506int:TNRC6B
InteractionZFP36 interactions

UBAP2L PRRC2C PAN3 LSM14B PRRC2A

8.44e-05181505int:ZFP36
InteractionFXR2 interactions

UBAP2L PRRC2C CECR2 MECOM TNIP1 LSM14B PRRC2A

8.67e-05430507int:FXR2
InteractionCTAGE7P interactions

MIA2 CTAGE6

8.99e-056502int:CTAGE7P
InteractionCTAGE6 interactions

MIA2 CTAGE6

8.99e-056502int:CTAGE6
InteractionCTAGE8 interactions

MIA2 CTAGE8

8.99e-056502int:CTAGE8
InteractionUBAP2L interactions

UBAP2L PRRC2C PAN3 ZCCHC2 LSM14B PRRC2A

9.14e-05298506int:UBAP2L
InteractionTLE5 interactions

ZNF48 MIA2 NAF1 DVL3 MECOM ZNF503 THAP7

1.04e-04443507int:TLE5
InteractionPHIP interactions

ZNF608 GLI3 CECR2 TRPS1 MECOM

1.26e-04197505int:PHIP
InteractionPHF21A interactions

ZCCHC8 NAF1 TRPS1 DVL3 MECOM TNIP1

1.97e-04343506int:PHF21A
InteractionRC3H2 interactions

PTPN14 UBAP2L ZCCHC8 PRRC2C NAF1 PAN3 TRAPPC14 PRRC2A

2.17e-04667508int:RC3H2
InteractionCNOT9 interactions

UBAP2L PRRC2C DVL3 PAN3 PRRC2A

2.64e-04231505int:CNOT9
InteractionLUC7L interactions

SETD2 ZCCHC8 TNIP1 LSM14B PRRC2A

3.27e-04242505int:LUC7L
InteractionMAGEB18 interactions

MIA2 TNIP1

3.27e-0411502int:MAGEB18
InteractionEWSR1 interactions

UBAP2L ZCCHC8 SEC24A CECR2 IGHM TRPS1 ETV3 TNIP1 PRRC2A

3.43e-04906509int:EWSR1
InteractionMEX3A interactions

PTPN14 UBAP2L PRRC2C TRPS1 DVL3 PRRC2A

3.60e-04384506int:MEX3A
InteractionPUM3 interactions

ZNF48 ETV3 MECOM PRRC2A THAP7

4.08e-04254505int:PUM3
InteractionHELZ interactions

UBAP2L PRRC2C PAN3 ZCCHC2 PRRC2A

4.30e-04257505int:HELZ
InteractionCTCFL interactions

SETD2 ZNF48 GLI3

4.90e-0462503int:CTCFL
InteractionCLIC3 interactions

MIA2 MECOM PAN3

5.14e-0463503int:CLIC3
InteractionUPF1 interactions

UBAP2L SEC24A CNTRL MECOM TNIP1 COLGALT1 PRRC2A

5.44e-04581507int:UPF1
InteractionPAN3 interactions

UBAP2L PAN3 PRRC2A

5.63e-0465503int:PAN3
InteractionWWTR1 interactions

SETD2 PTPN14 PRRC2C DVL3 TNIP1 PRRC2A

5.93e-04422506int:WWTR1
InteractionCPEB4 interactions

UBAP2L PRRC2C PAN3 PRRC2A

6.03e-04156504int:CPEB4
InteractionKLF16 interactions

PRRC2C TRPS1 MECOM TNIP1 PRRC2A ZNF503

6.16e-04425506int:KLF16
InteractionTNRC6A interactions

UBAP2L GLI3 CNTRL PAN3 PRRC2A

6.35e-04280505int:TNRC6A
Cytoband7q35

CTAGE8 CTAGE15 CTAGE6 CTAGE4

5.57e-07555447q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

CTAGE8 CTAGE15 CTAGE6 CTAGE4

1.17e-0666544chr7q35
GeneFamilyCTAGE family

CTAGE9 MIA2 CTAGE8 CTAGE15 CTAGE6 CTAGE4

2.81e-1315386907
GeneFamilyZinc fingers CCHC-type|RNA binding motif containing

ZCCHC8 ZCCHC2

1.25e-032538274
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD2 MECOM

2.31e-0334382487
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF48 ZNF608 GLI3 TRPS1 MECOM ZNF503

3.58e-0371838628
CoexpressionVALK_AML_CLUSTER_1

IGHM TRPS1 MECOM

2.75e-0529533M19844
CoexpressionTERAO_AOX4_TARGETS_HG_UP

CTAGE9 MIA2 CTAGE8

3.71e-0532533MM922
CoexpressionKRAS.DF.V1_DN

CTAGE9 PTPN14 NEUROD2 DVL3 LSM14B

4.43e-05193535M2861
CoexpressionBRACHAT_RESPONSE_TO_METHOTREXATE_DN

CTAGE9 MIA2 CTAGE8

6.26e-0538533MM1161
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA2 ZNF608 PRRC2C CECR2 CNTRL TRPS1

8.87e-08182546f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIA2 ZNF608 PRRC2C CECR2 CNTRL TRPS1

9.77e-081855467adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD2 MIA2 ZNF608 PRRC2C CNTRL

2.91e-061845451154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-35|World / Primary Cells by Cluster

NEUROD2 ZNF608 PRRC2C EPHA3 PROX1

4.17e-06198545de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NFE2 CECR2 ARMC9 EPHA3

5.91e-0697544eab10b1af9cd0ce373cd4d0316e0d7b218630584
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

NFE2 CECR2 ARMC9 EPHA3

5.91e-069754404f571708f2487b0dbd70ee507de6bf75be5f5d9
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTPN14 GLI3 MECOM EPHA3

4.89e-05166544f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PTPN14 GLI3 MECOM EPHA3

5.01e-051675445c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

CAPN9 ZNF608 CECR2 MECOM

5.37e-05170544269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 ABCA2 MECOM ZNF503

6.28e-05177544c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPN14 DPF3 NEUROD6 EPHA3

6.70e-051805442ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CAPN9 ZNF608 CECR2 MECOM

7.45e-05185544673f0c688ae6984bc8027df2da335787924f4137
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

RNF216 PAN3 LSM14B PROX1

7.93e-0518854414bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellBAL-Control-Lymphocyte-B-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF48 ZNF608 IGHM PABPC1L

8.26e-05190544da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF48 ZNF608 IGHM PABPC1L

8.26e-05190544682418a7a2096743112eae3790d40e7e600612c0
ToppCellBAL-Control-Lymphocyte-B-B_cell-B_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF48 ZNF608 IGHM PABPC1L

8.26e-0519054442312f7d79fe889397d32910b625793e2535cc26
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-22|World / Primary Cells by Cluster

NEUROD2 ZNF608 NEUROD6 EPHA3

8.78e-051935443b927d4b8ecb21a408424ef91a23746c21741f49
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CD248 GLI3 TRPS1 EPHA3

9.32e-05196544dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NEUROD2 ZNF608 NEUROD6 EPHA3

9.69e-0519854432d58379a89be19b6b1a494bf033416546771c19
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Immature_CPNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

NEUROD2 ZNF608 NEUROD6 EPHA3

9.69e-051985444e598aab92141e7d32ec963291ddeed14a21beba
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NEUROD2 NEUROD6 EPHA3

9.97e-0574543a50df7f4f7847b8aeff3fc6d521a69b50e05c719
ToppCellNeuronal-Excitatory-eC(RORB)-ESR1--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN14 DPF3 NEUROD6 EPHA3

1.01e-0420054432231471987dd5647c9f7c430ff62dc366b5aea8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

NEUROD2 NEUROD6 TENM2 EPHA3

1.01e-042005445b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCellNeuronal-Excitatory-eC(RORB)-ESR1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN14 DPF3 NEUROD6 EPHA3

1.01e-0420054482caaee79e697ed4ddea7dd49e99b7abe849604f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZNF608 LSM14B TENM2 PROX1

1.01e-04200544c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellNeuronal-Excitatory-eC(RORB)-ESR1---L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN14 DPF3 NEUROD6 EPHA3

1.01e-04200544622ca21b7949ec3d40e17ea08ce4212bbfb963db
ToppCellNeuronal-Excitatory-eC(RORB)-ESR1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTPN14 DPF3 NEUROD6 EPHA3

1.01e-042005440d559f7d8bfd24bcdc770fe2f3baebfddda9b640
ComputationalGenes in the cancer module 547.

IGHM NEUROD6

6.61e-0416262MODULE_547
ComputationalGenes in the cancer module 313.

IGHM NEUROD6

9.38e-0419262MODULE_313
ComputationalGenes in the cancer module 240.

IGHM NEUROD6

1.04e-0320262MODULE_240
ComputationalGenes in the cancer module 156.

IGHM NEUROD6

1.26e-0322262MODULE_156
DrugCefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

SETD2 CNTRL RNF216 LSM14B PRRC2A EPHA3

4.91e-062005063477_DN
Diseasemonocyte count

SETD2 ZNF608 NFE2 CECR2 TRPS1 ETV3 MECOM RNF216 ARMC9 PAN3

2.90e-0513204610EFO_0005091
Diseasegranulocyte percentage of myeloid white cells

SETD2 NFE2 MSANTD5 TRPS1 PAN3

6.02e-05268465EFO_0007997
Diseasemonocyte percentage of leukocytes

SETD2 NFE2 CECR2 TRPS1 MECOM ARMC9 PAN3

1.29e-04731467EFO_0007989
DiseaseMalignant neoplasm of breast

SETD2 PTPN14 MIA2 DVL3 MECOM TNIP1 TRAPPC8 PRRC2A

2.29e-041074468C0006142
Diseasetyrosine measurement

DPF3 TRPS1 NEUROD6

5.78e-04104463EFO_0005058
Diseasepathological myopia

CAPN9 VGLL2 TNIP1

6.99e-04111463EFO_0004207
DiseaseIniencephaly

GLI3 CECR2

8.76e-0428462C0152234
DiseaseTethered Cord Syndrome

GLI3 CECR2

8.76e-0428462C0080218
DiseaseSpinal Cord Myelodysplasia

GLI3 CECR2

8.76e-0428462C0344479
DiseaseExencephaly

GLI3 CECR2

8.76e-0428462C0266453
DiseaseNeurenteric Cyst

GLI3 CECR2

8.76e-0428462C0027806
DiseaseAcrania

GLI3 CECR2

8.76e-0428462C0702169
DiseaseDiastematomyelia

GLI3 CECR2

8.76e-0428462C0011999
DiseaseCraniorachischisis

GLI3 CECR2

9.40e-0429462C0152426
DiseaseNeural Tube Defects

GLI3 CECR2

1.01e-0330462C0027794
Diseaseplatelet component distribution width

SETD2 MIA2 NFE2 PRRC2C MECOM PRRC2A

1.08e-03755466EFO_0007984
Diseaseresponse to vaccine, cytokine measurement

CNTRL MECOM TENM2

1.13e-03131463EFO_0004645, EFO_0004873
Diseaselysine measurement

DPF3 MECOM

1.53e-0337462EFO_0005002
Diseasedentate gyrus volume measurement

GLI3 NEUROD6

1.70e-0339462EFO_0010083
Diseasehippocampal CA4 volume

GLI3 NEUROD6

1.88e-0341462EFO_0009396
Diseaseunipolar depression

ZNF608 TRPS1 DVL3 NEUROD6 TENM2 PRRC2A AK8

2.48e-031206467EFO_0003761
DiseaseC-reactive protein measurement

ZNF608 CD248 DPF3 TRPS1 TNIP1 ZCCHC2 EPHA3

2.48e-031206467EFO_0004458
Diseaseuric acid measurement

VGLL2 DPF3 MECOM NEUROD6 TENM2

2.53e-03610465EFO_0004761
Diseaseaminoadipic acid measurement

NAF1 TNIP1

2.78e-0350462EFO_0010459
Diseasealcohol consumption measurement

NEUROD2 ZNF608 GLI3 TRPS1 TENM2 AK8 EPHA3

2.93e-031242467EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
PFKRRGYWYFMPPPP

CNTRL

1136

Q7Z7A1
PHAPFAMRNIYPPRG

CTAGE4

746

Q8IX94
AMRNIYPPRGLPPYL

CTAGE4

751

Q8IX94
PHAPFAMRNIYPPRG

CTAGE6

746

Q86UF2
AMRNIYPPRGLPPYF

CTAGE6

751

Q86UF2
PHAPFAMRNIYPPRG

CTAGE8

746

P0CG41
AMRNIYPPRGLPPYL

CTAGE8

751

P0CG41
PHAPFAMRNIYPPRG

CTAGE9

746

A4FU28
AMRNIYPPRGLPPYL

CTAGE9

751

A4FU28
PHAPFAMRNIYPPRG

CTAGE15

746

A4D2H0
AMRNIYPPRGLPPYF

CTAGE15

751

A4D2H0
YPELFPAHQSPMFPD

CD248

521

Q9HCU0
LPLFARPGMYPDPHS

ETV3

231

P41162
HPGAAPWPMAFPYQY

DVL3

526

Q92997
FPPLYMPGLEYPNSA

CECR2

1136

Q9BXF3
YRPPQGMRYSYHPPP

CECR2

1196

Q9BXF3
NPHRSGKPAYYPFPQ

C9orf152

206

Q5JTZ5
MNGHVPYMYPALPPA

MSANTD5

186

A0A3B3IT52
YGPLLFMYVHPASPQ

OR5H8

251

P0DN80
VGALPYPSMFPLPFF

MECOM

686

Q03112
MDPRNGYMEPHYHPP

GLI3

111

P10071
SPPHPYINPYMDYIR

GLI3

191

P10071
YHMYCLNPPVAEPPE

DPF3

341

Q92784
HVPYSPFRGMAPYGP

LSM14B

111

Q9BX40
LPFYALPFVPNPMVH

ARMC9

146

Q7Z3E5
PVTGERYHLMYKPPP

AK8

396

Q96MA6
PLPFLLAYMPYCLPQ

OR51S1

166

Q8NGJ8
YHMHVFDRPYPLAPP

CUEDC1

136

Q9NWM3
YFLPAMPQPPAQAAY

PABPC1L

406

Q4VXU2
APLTGMVFPNYHIYP

PAN3

411

Q58A45
MVFPNYHIYPPTAPH

PAN3

416

Q58A45
APMPEPQAPGRYFAH

IGHM

381

P01871
VHPGMYGLPRPWYFP

ABCA2

916

Q9BZC7
YRLPPPMDCPAALYQ

EPHA3

841

P29320
QMLPGYRDPYHGRPL

COLGALT1

391

Q8NBJ5
MPYLYRAPGPQAHPV

CAPN9

1

O14815
HVPDPPYSYGNMAIP

NFE2

91

Q16621
FAMRNVYPPRGFPPY

MIA2

1356

Q96PC5
YMLRPPQPPVYLFVF

SEC24A

496

O95486
RHPFPLPLMAYPFQS

PROX1

481

Q92786
AHMLKNYLFRPPPPY

PTPN14

556

Q15678
PPYMFQQYPRMTYPP

PRRC2C

246

Q9Y520
QQYPRMTYPPLHGPM

PRRC2C

251

Q9Y520
YRGMMPPFMYPPYLP

PRRC2A

246

P48634
GFPRAKMYFVPPPYE

TENM2

2496

Q9NT68
FNNFPLNMGPIPAPY

RNF216

816

Q9NWF9
PSAYMLRLPPPAGAY

THAP7

211

Q9BT49
MAGFGRFYPVYPAPN

ZCCHC2

1101

Q9C0B9
PEHLCGAYPYAYPPM

TNIP1

541

Q15025
YMRPAKHPNYSPPGS

TRPS1

1071

Q9UHF7
LPPFIYRMRQLGYPP

ZCCHC8

306

Q6NZY4
HMEPQDFSFPGYPLP

ZNF48

381

Q96MX3
NPYIMAPGLLHAYPP

UBAP2L

801

Q14157
YAPHFDPRYGPLLMP

VGLL2

231

Q8N8G2
DYSMYFPAVPLPPRA

TRAPPC14

6

Q8WVR3
HHPFAGYPPGYPMQA

SETD2

2161

Q9BYW2
AGHPLYPYGFMLPND

ZNF503

496

Q96F45
YPYGFMLPNDPLPHI

ZNF503

501

Q96F45
LHAYPYPQMYDPSHP

ZNF608

1346

Q9ULD9
FLQPGAPRPYPAHYM

TRAPPC8

471

Q9Y2L5
HYLPYLMPSPGALLP

PRR29

111

P0C7W0
QYPFPLPVFDMHNFP

NAF1

421

Q96HR8
GGPFAMHPYPYPCSR

NEUROD2

231

Q15784
NYGMHYCAVPPRGPL

NEUROD6

286

Q96NK8