Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	ATP7A SLC38A5 PANX1 SLC39A8 RYR2 RYR3 ABCB1 GJA1 SLC9B1 NALCN ABCD3 ATP6V1C2 GJB7 ANO2 SLC25A41 RHBG ATP13A1 CLIC4 SLC1A7 SLC2A1 SLC8A1 SLC9A5 SLC12A4 SLC16A3 AP4M1 CDH17 GABRA4 SLC16A10	6.07e-05	1180	213	28	GO:0022857
GeneOntologyMolecularFunction	transporter activity	ATP7A SLC38A5 PANX1 SLC39A8 RYR2 RYR3 ABCB1 GJA1 SLC9B1 NALCN ABCD3 ATP6V1C2 GJB7 ANO2 SLC25A41 RHBG ATP13A1 CLIC4 APOB SLC1A7 SLC2A1 SLC8A1 SLC9A5 SLC12A4 SLC16A3 AP4M1 CDH17 GABRA4 SLC16A10	1.13e-04	1289	213	29	GO:0005215
GeneOntologyMolecularFunction	active transmembrane transporter activity	ATP7A SLC38A5 SLC39A8 ABCB1 SLC9B1 ABCD3 ATP6V1C2 ATP13A1 SLC1A7 SLC8A1 SLC9A5 SLC12A4 SLC16A3 CDH17 SLC16A10	1.96e-04	477	213	15	GO:0022804
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC38A5 PANX1 SLC39A8 ABCB1 GJA1 ABCD3 SLC25A41 SLC1A7 SLC2A1 SLC16A3 SLC16A10	3.24e-04	293	213	11	GO:0008514
GeneOntologyMolecularFunction	alanine-glyoxylate transaminase activity	MGAT4A AGXT2	3.37e-04	3	213	2	GO:0008453
GeneOntologyMolecularFunction	adenosine-phosphate deaminase activity	AMPD1 AMPD3	3.37e-04	3	213	2	GO:0047623
GeneOntologyMolecularFunction	AMP deaminase activity	AMPD1 AMPD3	3.37e-04	3	213	2	GO:0003876
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	ATP7A SLC38A5 SLC39A8 SLC9B1 ATP6V1C2 ATP13A1 SLC1A7 SLC8A1 SLC9A5 SLC12A4 SLC16A3	4.07e-04	301	213	11	GO:0022853
GeneOntologyMolecularFunction	scaffold protein binding	KIF1B PANX1 RYR2 GJA1 NOS1 CASP5	4.84e-04	93	213	6	GO:0097110
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ATP7A SLC38A5 PANX1 SLC39A8 RYR2 RYR3 SLC9B1 NALCN ATP6V1C2 ANO2 RHBG ATP13A1 CLIC4 SLC1A7 SLC8A1 SLC9A5 SLC12A4 SLC16A3 GABRA4	5.12e-04	758	213	19	GO:0015318
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC38A5 SLC9B1 SLC9A5	6.05e-04	16	213	3	GO:0015385
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	6.70e-04	4	213	2	GO:0005219
GeneOntologyBiologicalProcess	positive regulation of the force of heart contraction	RYR2 NOS1 SLC8A1	1.05e-05	5	212	3	GO:0098735
GeneOntologyCellularComponent	basolateral plasma membrane	ATP7A PTK2 SLC39A8 IQGAP1 DSTYK EZR RASGRF1 RHBG CASR SLC2A1 MSN SLC8A1 SLC16A3 CDH17 SLC16A10	1.23e-06	320	215	15	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	ATP7A PTK2 SLC39A8 IQGAP1 DSTYK EZR RASGRF1 RHBG CASR SLC2A1 MSN SLC8A1 SLC16A3 CDH17 SLC16A10	4.24e-06	354	215	15	GO:0009925
GeneOntologyCellularComponent	basal part of cell	ATP7A PTK2 SLC39A8 IQGAP1 DSTYK EZR RASGRF1 RHBG CASR SLC2A1 MSN SLC8A1 SLC16A3 CDH17 SLC16A10	9.32e-06	378	215	15	GO:0045178
GeneOntologyCellularComponent	apical part of cell	ATP7A MYO6 MPDZ PTK2 SLC39A8 IQGAP1 ABCB1 GJA1 DSTYK PLD1 EZR CLIC4 CASR SLC2A1 MSN SLC16A3 CYP4F3	1.42e-04	592	215	17	GO:0045177
GeneOntologyCellularComponent	apical plasma membrane	ATP7A MPDZ PTK2 SLC39A8 IQGAP1 ABCB1 GJA1 DSTYK PLD1 EZR CASR SLC2A1 MSN SLC16A3 CYP4F3	1.66e-04	487	215	15	GO:0016324
GeneOntologyCellularComponent	lysosome	SERPINA3 MYO6 NCF4 SLC39A8 BPI RRAGD AP2A2 SYT11 VPS13A ATP6V1C2 PLD1 NOS1 SFTPD APOB USP5 SNX14 SPPL2A SLC12A4 LNPEP CCT8	2.83e-04	811	215	20	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	SERPINA3 MYO6 NCF4 SLC39A8 BPI RRAGD AP2A2 SYT11 VPS13A ATP6V1C2 PLD1 NOS1 SFTPD APOB USP5 SNX14 SPPL2A SLC12A4 LNPEP CCT8	2.83e-04	811	215	20	GO:0000323
GeneOntologyCellularComponent	postsynapse	CELF4 ATP7A ATR KIF1A MYO6 KIF1B NAPA MPDZ RPS26 BCR PTK2 CYFIP1 AP2A2 SYT11 NOS1 SLC1A7 SNX14 SLC8A1 SLC9A5 SLC16A3 ARHGEF2 SMCR8 GABRA4	3.46e-04	1018	215	23	GO:0098794
GeneOntologyCellularComponent	platelet alpha granule	SERPINA3 CD109 F13A1 ALB VWF PROS1	4.00e-04	93	215	6	GO:0031091
GeneOntologyCellularComponent	vacuole	SERPINA3 MYO6 NCF4 TTC3 SLC39A8 BPI RRAGD AP2A2 SYT11 VPS13A ATP6V1C2 PLD1 NOS1 SFTPD APOB USP5 SNX14 SPPL2A SLC12A4 LNPEP CCT8	5.01e-04	913	215	21	GO:0005773
GeneOntologyCellularComponent	platelet alpha granule lumen	SERPINA3 F13A1 ALB VWF PROS1	6.32e-04	67	215	5	GO:0031093
GeneOntologyCellularComponent	vesicle lumen	SERPINA3 F13A1 CYFIP1 BPI VPS13A ALB AMPD3 VWF APOB CCT8 PROS1	6.82e-04	332	215	11	GO:0031983
GeneOntologyCellularComponent	blood microparticle	SERPINA3 F13A1 ALB SLC2A1 MSN ENG PROS1	7.38e-04	144	215	7	GO:0072562
GeneOntologyCellularComponent	sarcolemma	PTK2 RYR2 RYR3 NOS1 EZR SLC2A1 MSN SLC8A1	8.07e-04	190	215	8	GO:0042383
GeneOntologyCellularComponent	sarcoplasmic reticulum membrane	RYR2 RYR3 SRL NOS1	1.17e-03	45	215	4	GO:0033017
GeneOntologyCellularComponent	replication fork	NBN HMCES TIMELESS PRIM2 RPA1	1.19e-03	77	215	5	GO:0005657
GeneOntologyCellularComponent	cell-cell junction	MPDZ PANX1 PTK2 IQGAP1 ABCB1 GJA1 GJB7 EZR CLIC4 PTPRU SLC2A1 MSN SLC8A1 ARHGEF2 CDH17	1.24e-03	591	215	15	GO:0005911
Domain	Lipase_euk	LIPJ LIPF LIPK	2.66e-05	6	208	3	IPR025483
Domain	Abhydro_lipase	LIPJ LIPF LIPK	2.66e-05	6	208	3	PF04083
Domain	AB_hydrolase_lipase	LIPJ LIPF LIPK	2.66e-05	6	208	3	IPR006693
Domain	ARM-type_fold	ATR FMNL2 ARMCX1 RYR3 URB1 NF1 AP2A2 XPO4 APOB FRYL WDFY4 FMNL3 SF3B1 LTA4H	2.82e-05	339	208	14	IPR016024
Domain	Cell_morpho_N	FRYL FRY	1.23e-04	2	208	2	IPR025614
Domain	Cell_Morphogen_C	FRYL FRY	1.23e-04	2	208	2	IPR025481
Domain	MOR2-PAG1_mid	FRYL FRY	1.23e-04	2	208	2	IPR029473
Domain	MOR2-PAG1_mid	FRYL FRY	1.23e-04	2	208	2	PF14228
Domain	MOR2-PAG1_C	FRYL FRY	1.23e-04	2	208	2	PF14225
Domain	MOR2-PAG1_N	FRYL FRY	1.23e-04	2	208	2	PF14222
Domain	Ubiquitinyl_hydrolase	USP13 USP5	1.23e-04	2	208	2	IPR016652
Domain	RB_A	RBL1 RBL2	3.68e-04	3	208	2	IPR002720
Domain	DUF3452	RBL1 RBL2	3.68e-04	3	208	2	PF11934
Domain	RB_B	RBL1 RBL2	3.68e-04	3	208	2	IPR002719
Domain	AMPD	AMPD1 AMPD3	3.68e-04	3	208	2	IPR006329
Domain	RB_C	RBL1 RBL2	3.68e-04	3	208	2	IPR015030
Domain	Ryanodine_rcpt	RYR2 RYR3	3.68e-04	3	208	2	IPR003032
Domain	RB_fam	RBL1 RBL2	3.68e-04	3	208	2	IPR028309
Domain	RB_N	RBL1 RBL2	3.68e-04	3	208	2	IPR024599
Domain	Ryanrecept_TM4-6	RYR2 RYR3	3.68e-04	3	208	2	IPR009460
Domain	RB_A	RBL1 RBL2	3.68e-04	3	208	2	PF01858
Domain	RB_B	RBL1 RBL2	3.68e-04	3	208	2	PF01857
Domain	RyR	RYR2 RYR3	3.68e-04	3	208	2	PF02026
Domain	RR_TM4-6	RYR2 RYR3	3.68e-04	3	208	2	PF06459
Domain	DUF3452	RBL1 RBL2	3.68e-04	3	208	2	SM01367
Domain	Rb_C	RBL1 RBL2	3.68e-04	3	208	2	SM01369
Domain	RB_A	RBL1 RBL2	3.68e-04	3	208	2	SM01368
Domain	Ryan_recept	RYR2 RYR3	3.68e-04	3	208	2	IPR013333
Domain	ERM_C_dom	EZR MSN	7.30e-04	4	208	2	IPR011259
Domain	Kinesin-like_KIF1-typ	KIF1A KIF1B	7.30e-04	4	208	2	IPR022140
Domain	Pecanex_C	PCNX4 PCNX1	7.30e-04	4	208	2	PF05041
Domain	KIF1B	KIF1A KIF1B	7.30e-04	4	208	2	PF12423
Domain	ERM	EZR MSN	7.30e-04	4	208	2	PF00769
Domain	Pecanex	PCNX4 PCNX1	7.30e-04	4	208	2	IPR007735
Domain	A/AMP_deam_AS	AMPD1 AMPD3	7.30e-04	4	208	2	IPR006650
Domain	ERM	EZR MSN	7.30e-04	4	208	2	IPR011174
Domain	GDS_CDC24_CS	BCR RASGRF1 PREX2 ARHGEF2	9.06e-04	39	208	4	IPR001331
Domain	PH_dom-like	KIF1A KIF1B TBC1D2B BCR PTK2 PTPN13 PLD1 EZR RASGRF1 WDFY4 PREX2 MSN ARHGEF2	1.02e-03	426	208	13	IPR011993
Domain	FERM_M	PTK2 PTPN13 EZR MSN	1.69e-03	46	208	4	PF00373
Domain	RIH_assoc-dom	RYR2 RYR3	1.80e-03	6	208	2	IPR013662
Domain	Kinesin_assoc	KIF1A KIF1B	1.80e-03	6	208	2	PF16183
Domain	A_DEAMINASE	AMPD1 AMPD3	1.80e-03	6	208	2	PS00485
Domain	Ins145_P3_rec	RYR2 RYR3	1.80e-03	6	208	2	PF08709
Domain	Kinesin-like	KIF1A KIF1B	1.80e-03	6	208	2	IPR022164
Domain	RIH_assoc	RYR2 RYR3	1.80e-03	6	208	2	PF08454
Domain	A_deaminase	AMPD1 AMPD3	1.80e-03	6	208	2	PF00962
Domain	RIH_dom	RYR2 RYR3	1.80e-03	6	208	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	1.80e-03	6	208	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	1.80e-03	6	208	2	IPR015925
Domain	Kinesin_assoc	KIF1A KIF1B	1.80e-03	6	208	2	IPR032405
Domain	-	RYR2 RYR3	1.80e-03	6	208	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 RYR3	1.80e-03	6	208	2	PF01365
Domain	DUF3694	KIF1A KIF1B	1.80e-03	6	208	2	PF12473
Domain	A/AMP_deaminase_dom	AMPD1 AMPD3	1.80e-03	6	208	2	IPR001365
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP7A SLC38A5 SLC39A8 RYR2 RYR3 ABCB1 MICU1 SLC9B1 AP2A2 NALCN ABCD3 ALB ATP6V1C2 ANO2 RHBG ATP13A1 APOB SLC1A7 SLC2A1 SLC8A1 SLC9A5 SLC12A4 SLC16A3 SLC16A10	1.59e-06	681	167	24	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ATP7A SLC38A5 SLC39A8 RYR2 RYR3 ABCB1 MICU1 SLC9B1 AP2A2 NALCN ABCD3 ALB ATP6V1C2 ANO2 RHBG ATP13A1 APOB SLC1A7 SLC2A1 SLC8A1 SLC9A5 SLC12A4 SLC16A3 SLC16A10	6.07e-06	736	167	24	M27287
Pathway	PID_RAC1_REG_PATHWAY	BCR RASGRF1 PREX2 ARHGAP1 ARHGEF2	8.04e-05	38	167	5	M241
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GALNT1 GINM1 ATR LGR4 NAPA L2HGDH COG3 GJA1 NF1 VPS13A ANKIB1 TIMELESS GNPAT EZR TMEM248 TMEM41A ATP13A1 ST7 PRXL2A APOB PPA1 PIGU MSN ORC4 SLC12A4 ARHGEF2 CDH17 PROS1	1.33e-10	1061	216	28	33845483
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A MYO6 MCM6 MIDEAS ARMCX1 NT5DC1 PTK2 IQGAP1 URB1 CYFIP1 NF1 AP2A2 A2ML1 ABCD3 ANKIB1 HACD3 CLIC4 PPA1 SLC2A1 MSN MSH6 USP5 SF3B1 PRIM2 NUP133 CCT8 PDCD11 ARHGEF2 RPA1 ALDH7A1	1.70e-09	1353	216	30	29467282
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	PDXDC1 SETD1A MYO6 BCR FMNL2 ABCB1 PTPN13 NF1 ABCD3 ANKIB1 SLC2A1 FMNL3 USP5 ARHGEF2	1.21e-08	313	216	14	38270169
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PDXDC1 ATP7A MYO6 PANX1 IQGAP1 PTPN13 CYFIP1 NF1 SYT11 EZR MSN FMNL3 PACS1 SLC12A4 SLC16A3	1.71e-08	377	216	15	38117590
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	MYO6 L2HGDH NBN MCM6 RPS26 HMCES HACD3 PPA1 YARS1 ORC4 MSH6 USP5 SF3B1 PRIM2 NUP133 LTA4H RPA1	4.90e-08	534	216	17	35032548
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HIVEP1 ATR KIF1A MYO6 MCM6 RPS26 TTC3 IQGAP1 URB1 CYFIP1 NF1 AP2A2 ABCD3 TMEM117 EZR HACD3 ATP13A1 HAT1 APOB PPA1 SLC2A1 YARS1 MSH6 SF3B1 NUP133 CCT8 PDCD11 RPA1	7.98e-08	1425	216	28	30948266
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDXDC1 MYO6 NAPA L2HGDH NBN MCM6 TUBGCP4 IQGAP1 CYFIP1 AP2A2 ABCD3 TIMELESS GNPAT HAT1 PAF1 MSH6 NUP133	9.65e-08	560	216	17	35241646
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 ATP7A ACACB MYO6 KIF1B LGR4 NDRG3 FMNL2 RYR2 PTPN13 VPS13A ABCD3 ALB PLD1 APOB ARHGAP1 SF3B1 CCT8 AP4M1 SMCR8	1.02e-07	777	216	20	35844135
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PDXDC1 ATP7A KIF1A ZFYVE16 COG3 CDKAL1 PTPN13 VPS13A ABCD3 PLD1 ST7 PIGU SNX14 SLC12A4 LNPEP SMCR8	1.28e-07	504	216	16	34432599
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KIF1A MYO6 KIF1B BACH1 NAPA TTC3 FMNL2 PTK2 RYR3 IQGAP1 MICU1 NAA25 PTPN13 STAMBPL1 EZR USP13 VWF ATP13A1 RBL2 CLIC4 YARS1 ARHGAP1 FRY SF3B1 YLPM1 ANKRD36	1.38e-07	1285	216	26	35914814
Pubmed	NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse.	ATR NBN RPA1	2.36e-07	3	216	3	18003706
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	GALNT1 URB1 PTPN13 TMEM181 HACD3 ATP13A1 AGPAT2 APOB PIGU SF3B1 PDCD11 ARHGEF2	3.90e-07	296	216	12	34186245
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	KIF1B NAPA MCM6 RPS26 ENOPH1 IQGAP1 NAA25 CYFIP1 A2ML1 EZR AMPD1 HAT1 CLIC4 FRYL PPA1 SLC2A1 MSN ARHGAP1 MSH6 USP5 SF3B1 YLPM1 CCT8 PDCD11 LTA4H ALDH7A1	4.48e-07	1367	216	26	32687490
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	CDKAL1 GJA1 AP2A2 TMEM181 HACD3 ATP13A1 RBL1 RBL2 APOB PIGU SLC2A1 SNX14 SLC12A4 SLC16A3 ENG	6.33e-07	499	216	15	22810586
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ATP7A MYO6 BACH1 MPDZ NBN TTC3 CDKAL1 MICU1 DNAJB13 GJA1 URB1 PTPN13 VPS13A ABCD3 SCO1 HACD3 ATP13A1 ST7 PAF1 PIGU SLC2A1 ARHGAP1 SF3B1 LNPEP NUP133 PDCD11 SMCR8	6.50e-07	1487	216	27	33957083
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ATR MPDZ L2HGDH TUBGCP4 BCR PTK2 DSTYK ABCD3 ANKIB1 TIMELESS GNPAT USP13 RBL1 MSN PACS1 ARHGEF2 CMTR2	7.71e-07	650	216	17	38777146
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PDXDC1 KIF1A ZFYVE16 CD109 MPDZ MCM6 BCR CDKAL1 CYFIP1 ABCD3 SCO1 HACD3 DUSP6 XPO4 PTPRU ARHGAP1 MSH6 USP5 LNPEP NUP133 CCT8	8.74e-07	974	216	21	28675297
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MYO6 TTC21A KIF1B RPS26 BCR FMNL2 IQGAP1 GJA1 CYFIP1 NF1 AP2A2 ABCD3 ALB DNAH6 NOS1 VWF HACD3 SLC2A1 YARS1 PACS1 USP5 AGO1 SF3B1 CCT8 ARHGEF2 ALDH7A1	1.05e-06	1431	216	26	37142655
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ATR NBN MCM6 NT5DC1 IQGAP1 JMJD6 USP13 HAT1 PPA1 PAF1 YARS1 MSN MSH6 USP5 SF3B1 PRIM2 YLPM1 NUP133 CCT8 LTA4H RPA1	1.65e-06	1014	216	21	32416067
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	KIF1A MPDZ TUBGCP4 PTK2 IQGAP1 NF1 SYT11 A2ML1 ALB EZR PREX2 MSN FRY AGO1	1.90e-06	475	216	14	31040226
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GALNT1 GINM1 ATR CD109 LGR4 SLC38A5 NT5DC1 CDKAL1 GJA1 NF1 TIMELESS TMEM248 HACD3 AGPAT2 PRXL2A PIGU USP5 SNX14 SLC16A3 LNPEP CCT8 ENG PROS1	1.93e-06	1201	216	23	35696571
Pubmed	Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton.	MYO6 KIF1B SLC2A1	2.34e-06	5	216	3	10198040
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATP7A ZFYVE16 MYO6 KIF1B MPDZ CDKAL1 IQGAP1 PTPN13 CYFIP1 ABCD3 EZR HACD3 MSN ARHGAP1 CCT8 RPA1 SMCR8	2.45e-06	708	216	17	39231216
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TTC21A KIF1B BACH1 MCM6 TUBGCP4 BCR FMNL2 IQGAP1 MICU1 PTPN13 CYFIP1 NF1 AP2A2 ABCD3 SCO1 EZR RBL1 AGPAT2 XPO4 PPA1 PIGU PACS1 NUP133 RPA1	2.83e-06	1321	216	24	27173435
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MPDZ TTC3 BCR PTK2 IQGAP1 CYFIP1 NF1 AP2A2 NOS1 EZR PAF1 MSN FRY AGO1 SF3B1 ZNF516 YLPM1 CCT8 ARHGEF2 RPA1	2.83e-06	963	216	20	28671696
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CD109 NAPA L2HGDH RPS26 TUBGCP4 COG3 CDKAL1 IQGAP1 GJA1 URB1 AP2A2 ABCD3 HACD3 ST7 AGPAT2 XPO4 HAT1 MSH6 USP5 SF3B1 NUP133 CCT8 PDCD11 ARHGEF2 RPA1	3.84e-06	1440	216	25	30833792
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	PDXDC1 RPS26 TUBGCP4 NF1 VPS13A ABCD3 HACD3 XPO4 PIGU SLC2A1 YARS1 MSH6 SF3B1 NUP133 PCNX1 SLC16A10	4.08e-06	657	216	16	36180527
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	GALNT1 LGR4 TTC3 NT5DC1 F13A1 URB1 PTPN13 RRAGD TIMELESS PLD1 TMEM181 EZR TMEM248 APOB FRYL COX18 WDFY4 SLC2A1 ORC4 PACS1 RPA1	4.65e-06	1084	216	21	11544199
Pubmed	GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP.	MYO6 KIF1B SLC2A1	4.66e-06	6	216	3	15975910
Pubmed	MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.	FMNL2 CDKAL1 ABCD3 FRYL FMNL3 PRIM2 ARHGEF2 SMCR8	4.80e-06	150	216	8	22678362
Pubmed	Functional proteomics mapping of a human signaling pathway.	HIVEP1 ZFYVE16 MYO6 TTC3 FMNL2 RYR2 AP2A2 USP13 VWF FMNL3 USP5 SF3B1 SLC12A4 LNPEP YLPM1	5.03e-06	591	216	15	15231748
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	SERPINA3 MYO6 NAPA ADGRV1 BCR NDRG3 IQGAP1 ABCB1 PTPN13 BPI ALB ATP6V1C2 VWF RBL2 CLIC4 MSN ARHGAP1 CCT8 LTA4H AP4M1	6.27e-06	1016	216	20	19056867
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HIVEP1 ATR KIF1B BACH1 NBN IQGAP1 NF1 TIMELESS HACD3 PACS1 MSH6 SF3B1 ZNF516 YLPM1 ELK3 ARHGEF2 CDH17	7.90e-06	774	216	17	15302935
Pubmed	Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.	ATR TIMELESS RPA1	8.12e-06	7	216	3	20233725
Pubmed	The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.	COL10A1 RBL1 RBL2	8.12e-06	7	216	3	15124025
Pubmed	BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.	ATR NBN RPA1	8.12e-06	7	216	3	16872911
Pubmed	The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.	ATR NBN RPA1	8.12e-06	7	216	3	17526493
Pubmed	SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathway.	NBN TIMELESS RPA1	8.12e-06	7	216	3	24990965
Pubmed	Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells.	RBL1 RBL2 PPA1	8.12e-06	7	216	3	33537097
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	PDXDC1 NAPA PANX1 CDKAL1 VPS13A ATP13A1 ST7 PRXL2A PIGU ARHGAP1 SLC12A4 LNPEP SMCR8	8.40e-06	468	216	13	31056421
Pubmed	Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.	MCM6 RPS26 IQGAP1 CYFIP1 ABCD3 PAF1 NUP133 ARHGEF2 RPA1	8.81e-06	215	216	9	30462309
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	PDXDC1 ATP7A MYO6 COG3 CDKAL1 GJA1 PTPN13 HACD3 ATP13A1 PRXL2A CLIC4 SLC2A1 MSN ARHGAP1 SLC12A4 LNPEP NUP133 SMCR8 SLC16A10	8.90e-06	952	216	19	38569033
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	SERPINA3 ALB VWF APOB TG ARHGAP1 USP5 PROS1	9.68e-06	165	216	8	14718574
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ZFYVE16 NBN PTPN13 VPS13A ABCD3 ST7 DUSP6 XPO4 PTPRU PAF1 ARHGAP1 PACS1 MSH6 SLC12A4 LNPEP PRIM2 YLPM1 NUP133 ARHGEF2 RPA1	9.98e-06	1049	216	20	27880917
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	PDXDC1 ACACB ZFYVE16 TBC1D2B PTK2 CDKAL1 CLIC4 ARHGAP1 SLC16A3 LNPEP SMCR8	1.01e-05	339	216	11	37232246
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ZFYVE16 MYO6 MPDZ NBN MCM6 RPS26 BCR HSP90AA5P IQGAP1 AP2A2 ABCD3 HACD3 HAT1 PAF1 ORC4 MSH6 SF3B1 PRIM2 CCT8 PCNX1 ARHGEF2 RPA1 ALDH7A1	1.09e-05	1335	216	23	29229926
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	MYO6 MPDZ MCM6 RPS26 IQGAP1 CYFIP1 AP2A2 EZR HAT1 CLIC4 PPA1 PAF1 YARS1 MSN MSH6 USP5 SF3B1 CCT8 LTA4H RPA1 ALDH7A1	1.12e-05	1149	216	21	35446349
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	HIVEP1 ACACB MYO6 NBN RYR2 CYFIP1 NF1 VPS13A PPP2R3C AMPD1 PIGU ZNF516 ARHGEF2 SMCR8 CDH17	1.24e-05	638	216	15	31182584
Pubmed	Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.	ALB RBL1 RBL2	1.29e-05	8	216	3	25017070
Pubmed	Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli.	IQGAP1 EZR CLIC4	1.29e-05	8	216	3	10793131
Pubmed	p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development.	COL10A1 RBL1 RBL2	1.29e-05	8	216	3	12086466
Pubmed	Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.	GALNT1 GALNT13 ALB GALNT17	1.39e-05	24	216	4	31740596
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	NBN BCR ABCB1 BPI EZR SFTPD CASR APOB SLC2A1 GSTT1 MSH6 ENG	1.45e-05	421	216	12	19692168
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	ATP7A PANX1 CYFIP1 NF1 MSN SLC12A4 LNPEP	1.54e-05	127	216	7	30442766
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF1A MCM6 RPS26 IQGAP1 URB1 NF1 FRYL MSN MSH6 USP5 SF3B1 YLPM1 NUP133 PDCD11 LTA4H	1.63e-05	653	216	15	22586326
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	ATR MCM6 USP13 MSH6 USP5 YLPM1	1.78e-05	87	216	6	17148452
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	HIVEP1 MYO6 MPDZ MCM6 TMEM104 BCR IQGAP1 MICU1 ABCD3 ALB STAMBPL1 EZR NEPRO USP13 HAT1 USP5 PRIM2 YLPM1 ARHGEF2	1.88e-05	1005	216	19	19615732
Pubmed	Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA.	BCR IQGAP1 ARHGAP1	1.93e-05	9	216	3	9535855
Pubmed	MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.	MCM6 IQGAP1 ALB YARS1 MSN CCT8 LTA4H RPA1	1.97e-05	182	216	8	30711629
Pubmed	PEX14 is required for microtubule-based peroxisome motility in human cells.	IQGAP1 ABCD3 GNPAT CCT8 ARHGEF2	2.18e-05	54	216	5	21525035
Pubmed	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.	ATR COG3 NF1 XPO4	2.27e-05	27	216	4	23027611
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MYO6 MCM6 RPS26 HSP90AA5P CYFIP1 SCO1 DNAH6 EZR HACD3 HAT1 PAF1 SLC2A1 MSN MSH6 USP5 SF3B1 CCT8	2.50e-05	847	216	17	35235311
Pubmed	Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism.	SERPINA3 MCM6 ALB PAF1 USP5 CCT8	2.60e-05	93	216	6	22079093
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDXDC1 GALNT1 KIF1A MYO6 MCM6 CDKAL1 IQGAP1 GJA1 URB1 NAA25 ABCD3 TIMELESS HACD3 ATP13A1 HAT1 USP5 NUP133 ARHGEF2	2.74e-05	942	216	18	31073040
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SETD1A ACACB MCM6 RPS26 CDKAL1 AP2A2 JMJD6 ABCD3 ALB HACD3 HAT1 PPA1 PAF1 SLC2A1 YARS1 ORC4 MSH6 SF3B1 CCT8 PDCD11 ARHGEF2 RPA1	2.75e-05	1318	216	22	30463901
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	RYR2 RYR3 VWF CASR SLC1A7 SLC2A1 SLC8A1	3.31e-05	143	216	7	20424473
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	ATR KIF1A TUBGCP4 TTC3 RYR2 AP2A2 PLD1 PACS1 FRY AGO1 YLPM1 GABRA4	3.61e-05	462	216	12	31138677
Pubmed	Early expression of p107 is associated with 3T3-L1 adipocyte differentiation.	RBL1 RBL2	3.84e-05	2	216	2	12242027
Pubmed	Revisiting the human polypeptide GalNAc-T1 and T13 paralogs.	GALNT1 GALNT13	3.84e-05	2	216	2	27913570
Pubmed	Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe.	ATR TIMELESS	3.84e-05	2	216	2	37144518
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	3.84e-05	2	216	2	8898078
Pubmed	A common 253-kb deletion involving VWF and TMEM16B in German and Italian patients with severe von Willebrand disease type 3.	ANO2 VWF	3.84e-05	2	216	2	17371490
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	3.84e-05	2	216	2	14550562
Pubmed	Loss of the mammalian DREAM complex deregulates chondrocyte proliferation.	RBL1 RBL2	3.84e-05	2	216	2	24710275
Pubmed	HIV gp120 Protein Increases the Function of Connexin 43 Hemichannels and Pannexin-1 Channels in Astrocytes: Repercussions on Astroglial Function.	PANX1 GJA1	3.84e-05	2	216	2	32260308
Pubmed	Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.	BACH1 RYR2	3.84e-05	2	216	2	36453019
Pubmed	Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells.	RBL1 RBL2	3.84e-05	2	216	2	16537896
Pubmed	Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.	OR4F4 OR4F17	3.84e-05	2	216	2	11689484
Pubmed	Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.	OR4F4 OR4F17	3.84e-05	2	216	2	11689483
Pubmed	Moesin: a member of the protein 4.1-talin-ezrin family of proteins.	EZR MSN	3.84e-05	2	216	2	1924289
Pubmed	Role of overexpression of MACC1 and/or FAK in predicting prognosis of hepatocellular carcinoma after liver transplantation.	PTK2 MACC1	3.84e-05	2	216	2	24516351
Pubmed	[AMPD genes and urate metabolism].	AMPD1 AMPD3	3.84e-05	2	216	2	18409530
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	3.84e-05	2	216	2	21531043
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	3.84e-05	2	216	2	16678258
Pubmed	Expression of p107 and p130 during human adipose-derived stem cell adipogenesis.	RBL1 RBL2	3.84e-05	2	216	2	18086563
Pubmed	Cx43 Hemichannel and Panx1 Channel Modulation by Gap19 and 10Panx1 Peptides.	PANX1 GJA1	3.84e-05	2	216	2	37511370
Pubmed	Alternative splicing in the Atp7a gene in the Cu deficient mosaic mutation in mice.	ATP7A COL10A1	3.84e-05	2	216	2	19058563
Pubmed	Preservation of transendothelial glucose transporter 1 and P-glycoprotein transporters in a cortical slice culture model of the blood-brain barrier.	ABCB1 SLC2A1	3.84e-05	2	216	2	20603190
Pubmed	Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiation.	RBL1 RBL2	3.84e-05	2	216	2	9747874
Pubmed	Bcr encodes a GTPase-activating protein for p21rac.	BCR ARHGAP1	3.84e-05	2	216	2	1903516
Pubmed	Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.	RYR2 SLC8A1	3.84e-05	2	216	2	22456474
Pubmed	FMNL formins boost lamellipodial force generation.	FMNL2 FMNL3	3.84e-05	2	216	2	28327544
Pubmed	N-terminal sequence and distal histidine residues are responsible for pH-regulated cytoplasmic membrane binding of human AMP deaminase isoform E.	AMPD1 AMPD3	3.84e-05	2	216	2	12213808
Pubmed	Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion.	PTK2 EZR	3.84e-05	2	216	2	11468295
Pubmed	Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of alpha IIb beta 3 engagement.	PTK2 VWF	3.84e-05	2	216	2	12543870
Pubmed	Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin.	NF1 RASGRF1	3.84e-05	2	216	2	30337665
Pubmed	RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes.	RYR2 GJA1	3.84e-05	2	216	2	31841141
Pubmed	Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model.	PANX1 GJA1	3.84e-05	2	216	2	23827947
Pubmed	Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.	PLD1 VWF	3.84e-05	2	216	2	18945966
Pubmed	Nbs1 is required for ATR-dependent phosphorylation events.	ATR NBN	3.84e-05	2	216	2	15616588
Interaction	RHOA interactions	PDXDC1 ATP7A MYO6 LGR4 NAPA SLC38A5 PANX1 BCR FMNL2 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 NF1 AP2A2 VPS13A ABCD3 SCO1 PLD1 EZR RASGRF1 HACD3 ATP13A1 ST7 FRYL PPA1 PIGU SLC2A1 PREX2 YARS1 MSN FMNL3 ARHGAP1 SLC12A4 SLC16A3 LNPEP PDCD11 ARHGEF2 RPA1 SMCR8	1.45e-11	1199	211	41	int:RHOA
Interaction	RAC1 interactions	ATP7A ZFYVE16 MYO6 TBC1D2B LGR4 SLC38A5 PANX1 BCR FMNL2 PTK2 IQGAP1 GJA1 PTPN13 CYFIP1 NF1 AP2A2 VPS13A PLD1 EZR VWF RASGRF1 HACD3 ATP13A1 PPA1 SLC2A1 PREX2 YARS1 ARHGAP1 PACS1 SLC12A4 SLC16A3 LNPEP ARHGEF2 RPA1 IMMP2L	1.54e-09	1063	211	35	int:RAC1
Interaction	RAC3 interactions	PDXDC1 ATP7A ZFYVE16 TBC1D2B LGR4 SLC38A5 PANX1 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 NF1 VPS13A ABCD3 HACD3 FRYL PPA1 SLC2A1 ARHGAP1 SLC12A4 SLC16A3 LNPEP	1.56e-07	619	211	23	int:RAC3
Interaction	RAB35 interactions	PDXDC1 ATP7A TBC1D2B PANX1 NDRG3 FMNL2 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 VPS13A ABCD3 PLD1 GNPAT SLC2A1 ARHGAP1 SLC12A4 LNPEP RPA1 SMCR8	6.97e-07	573	211	21	int:RAB35
Interaction	GJD3 interactions	PDXDC1 ATP7A ZFYVE16 MYO6 COG3 FMNL2 CDKAL1 GJA1 PTPN13 PLD1 HACD3 ATP13A1 ST7 PIGU SLC2A1 ARHGAP1 LNPEP SMCR8	1.50e-06	454	211	18	int:GJD3
Interaction	MCAM interactions	PDXDC1 ATP7A MYO6 PANX1 FMNL2 HSP90AA5P IQGAP1 GJA1 PTPN13 CYFIP1 NF1 SYT11 EZR MSN FMNL3 PACS1 SLC12A4 SLC16A3	2.31e-06	468	211	18	int:MCAM
Interaction	RAC2 interactions	PDXDC1 ZFYVE16 MYO6 NAPA PANX1 CDKAL1 IQGAP1 GJA1 CYFIP1 VPS13A ABCD3 PLD1 HACD3 PPA1 PIGU SLC2A1 FMNL3 ARHGAP1 USP5 SLC12A4 SLC16A3 LNPEP	2.53e-06	674	211	22	int:RAC2
Interaction	RND2 interactions	PDXDC1 MYO6 TBC1D2B MCM6 CDKAL1 GJA1 PTPN13 CYFIP1 VPS13A ABCD3 PPA1 SLC2A1 YARS1 ARHGAP1 SLC12A4 LNPEP SMCR8	4.19e-06	440	211	17	int:RND2
Interaction	RHOQ interactions	ZFYVE16 PANX1 IQGAP1 ABCB1 GJA1 PTPN13 NF1 RRAGD AP2A2 VPS13A PLD1 PPA1 SLC2A1 ARHGAP1 SLC12A4 LNPEP SMCR8	4.45e-06	442	211	17	int:RHOQ
Interaction	IFITM1 interactions	PDXDC1 KIF1A ZFYVE16 MYO6 NAPA AP2A2 SYT11 APOB PPA1 YARS1 ARHGAP1 LNPEP AP4M1 RPA1 SMCR8	5.40e-06	355	211	15	int:IFITM1
Interaction	RHOB interactions	ATP7A ZFYVE16 MYO6 TBC1D2B SLC38A5 PANX1 BCR FMNL2 IQGAP1 GJA1 PTPN13 CYFIP1 NF1 VPS13A PLD1 HACD3 PPA1 SLC2A1 MSN ARHGAP1 SLC12A4 SLC16A3 LNPEP ARHGEF2	8.44e-06	840	211	24	int:RHOB
Interaction	RHOF interactions	PDXDC1 ATP7A ATR MYO6 SLC38A5 MPDZ PANX1 IQGAP1 NAA25 PTPN13 CYFIP1 VPS13A HACD3 SLC2A1 YARS1 ARHGAP1 GSTT1 PACS1 SLC12A4 SLC16A3 LNPEP	8.64e-06	673	211	21	int:RHOF
Interaction	RHOG interactions	PDXDC1 ZFYVE16 TBC1D2B SLC38A5 PANX1 CDKAL1 IQGAP1 GJA1 CYFIP1 RRAGD VPS13A ABCD3 SCO1 PLD1 ST7 PIGU SLC2A1 PREX2 ARHGAP1 PACS1 SLC12A4 SLC16A3 LNPEP RPA1 SMCR8	1.06e-05	910	211	25	int:RHOG
Interaction	RHOC interactions	ATP7A LGR4 PANX1 BCR FMNL2 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 VPS13A ABCD3 HACD3 PPA1 PIGU SLC2A1 ARHGAP1 SLC12A4 LNPEP	1.33e-05	584	211	19	int:RHOC
Interaction	RAB5C interactions	ATP7A GINM1 ZFYVE16 SLC38A5 TTC3 CDKAL1 GJA1 DSTYK VPS13A ABCD3 PLD1 ATP13A1 DUSP6 SLC2A1 ARHGAP1 SLC12A4 LNPEP RPA1 SMCR8	1.93e-05	600	211	19	int:RAB5C
Interaction	RAB11A interactions	PDXDC1 SERPINA3 ACACB ATR ZFYVE16 TBC1D2B NAPA PANX1 CDKAL1 ABCB1 VPS13A ABCD3 PLD1 CLIC4 SLC2A1 ARHGAP1 SLC12A4 SLC16A3 LNPEP NUP133 PDCD11 RPA1 SMCR8	2.14e-05	830	211	23	int:RAB11A
Interaction	RHOH interactions	MYO6 MCM6 PANX1 CDKAL1 GJA1 PTPN13 CYFIP1 VPS13A ABCD3 HACD3 PPA1 SLC2A1 YARS1 ARHGAP1 SLC12A4 LNPEP SMCR8	2.97e-05	512	211	17	int:RHOH
Interaction	RHOD interactions	PDXDC1 MYO6 SLC38A5 MCM6 FMNL2 CDKAL1 IQGAP1 PTPN13 CYFIP1 VPS13A ABCD3 HACD3 PPA1 SLC2A1 ARHGAP1 SLC12A4 SLC16A3 LNPEP	3.49e-05	572	211	18	int:RHOD
Interaction	GPR17 interactions	PDXDC1 ATR TUBGCP4 COG3 GJA1 URB1 NAA25 DSTYK TIMELESS PRXL2A XPO4 PIGU	4.62e-05	283	211	12	int:GPR17
Interaction	CDC42 interactions	PDXDC1 ATR MYO6 MCM6 PANX1 BCR FMNL2 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 NF1 AP2A2 VPS13A ABCD3 SCO1 PLD1 HACD3 FRYL PPA1 SLC2A1 PREX2 YARS1 FMNL3 ARHGAP1 SLC12A4 SLC16A3 LNPEP RPA1	5.25e-05	1323	211	30	int:CDC42
Interaction	LAMP3 interactions	PDXDC1 ATP7A KIF1A ZFYVE16 FMNL2 CDKAL1 ABCB1 GJA1 DSTYK PLD1 ATP13A1 SLC2A1 ARHGAP1 SLC12A4 LNPEP SMCR8	5.66e-05	486	211	16	int:LAMP3
Interaction	RAB9A interactions	PDXDC1 KIF1A ZFYVE16 MYO6 KIF1B NAPA CDKAL1 RRAGD VPS13A ABCD3 PLD1 HACD3 SLC2A1 ARHGAP1 SNX14 LNPEP PDCD11 SMCR8	5.81e-05	595	211	18	int:RAB9A
Interaction	BRF2 interactions	ABCD3 HACD3 RBL2 XPO4 SF3B1	7.45e-05	42	211	5	int:BRF2
Interaction	AP2A1 interactions	MYO6 BCR IQGAP1 CYFIP1 AP2A2 GJB7 EZR SLC25A41 WDFY4 PACS1 SF3B1 RPA1	7.83e-05	299	211	12	int:AP2A1
Interaction	PHF11 interactions	SERPINA3 NAPA A2ML1 ENDOU ALB AGPAT2 APOB ARHGAP1	9.95e-05	137	211	8	int:PHF11
Interaction	RAB2A interactions	PDXDC1 ATP7A BCR FMNL2 IQGAP1 GJA1 GARIN4 VPS13A ABCD3 STAMBPL1 PLD1 SLC25A41 SLC2A1 ARHGAP1 SLC12A4 LNPEP RPA1	1.04e-04	567	211	17	int:RAB2A
Interaction	EED interactions	PDXDC1 ACACB MYO6 BACH1 NAPA MCM6 RPS26 IQGAP1 GJA1 URB1 NAA25 CYFIP1 AP2A2 ABCD3 ALB EZR SFTPD RBL1 XPO4 SLC2A1 FMNL3 ARHGAP1 MSH6 USP5 SF3B1 ZNF516 YLPM1 NUP133 CCT8 PDCD11 RPA1	1.08e-04	1445	211	31	int:EED
Interaction	ARF6 interactions	MYO6 COG3 FMNL2 CDKAL1 IQGAP1 GJA1 CYFIP1 ABCD3 PLD1 EZR ATP13A1 SLC2A1 YARS1 ARHGAP1 SLC12A4 LNPEP RPA1	1.48e-04	584	211	17	int:ARF6
Interaction	LAMP1 interactions	PDXDC1 ATP7A ZFYVE16 CDKAL1 IQGAP1 GJA1 PTPN13 CYFIP1 AP2A2 PLD1 HACD3 ATP13A1 SLC2A1 ARHGAP1 ORC4 LNPEP RPA1 SLC16A10	1.57e-04	644	211	18	int:LAMP1
Cytoband	10q23.31	LIPJ STAMBPL1 LIPF LIPK	1.98e-05	34	216	4	10q23.31
Cytoband	6q21-q22	COL10A1 SLC16A10	6.59e-05	3	216	2	6q21-q22
GeneFamily	Solute carriers	SLC38A5 SLC39A8 SLC9B1 SLC25A41 RHBG SLC1A7 SLC2A1 SLC8A1 SLC9A5 SLC12A4 SLC16A3 SLC16A10	1.08e-04	395	149	12	752
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	2.01e-04	3	149	2	287
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT1 GALNT13 GALNT17	5.64e-04	20	149	3	433
GeneFamily	Lipases\|Arylacetamide deacetylase family	LIPJ LIPF LIPK	7.53e-04	22	149	3	464
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTK2 PTPN13 EZR MSN	7.60e-04	50	149	4	1293
GeneFamily	Adenosine deaminase family	AMPD1 AMPD3	9.90e-04	6	149	2	1302
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	BCR RASGRF1 PREX2 ARHGEF2	2.15e-03	66	149	4	722
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 A2ML1	2.34e-03	9	149	2	1234
Coexpression	GSE17721_CTRL_VS_CPG_24H_BMDC_UP	CELF4 KIF1A L2HGDH CDKAL1 DNAJB13 DSTYK CYP4F3 AP4M1 IMMP2L CDH17	5.97e-06	200	213	10	M3771
Coexpression	GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP	KIF1A MPDZ L2HGDH DSTYK HAT1 HTRA3 MLXIP CYP4F3 AP4M1 IMMP2L	5.97e-06	200	213	10	M3679
Coexpression	GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_DN	NBN TUBGCP4 COG3 URB1 LIPT2 TMEM248 AGPAT2 COX18 ORC4 NUP133	5.97e-06	200	213	10	M7356
Coexpression	CUI_TCF21_TARGETS_2_DN	HIVEP1 ATP7A GINM1 ZFYVE16 MYO6 KIF1B FMNL2 ARMCX1 ABCB1 MICU1 DSTYK VPS13A PLD1 DUSP6 FRYL PREX2 FRY LNPEP ST6GALNAC3 PROS1 GABRA4	7.13e-06	854	213	21	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	HIVEP1 ATP7A GINM1 ZFYVE16 MYO6 KIF1B FMNL2 ARMCX1 ABCB1 MICU1 DSTYK VPS13A PLD1 DUSP6 FRYL PREX2 FRY LNPEP ST6GALNAC3 PROS1 GABRA4	1.28e-05	888	213	21	MM1018
Coexpression	DESCARTES_ORGANOGENESIS_ENDOTHELIAL_CELLS	MYO6 CD109 PTK2 ABCB1 HTRA3 PREX2 MSN FMNL3 LPAR6 ELK3 ENG	1.53e-05	272	213	11	MM3634
Coexpression	FAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_1	MYO6 SLC38A5 BCR SLC39A8 ABCB1 GJA1 VWF PRXL2A CLIC4 PPA1 SLC2A1 PREX2 FRY ENG	1.63e-05	440	213	14	M39039
Coexpression	GSE15659_TREG_VS_TCONV_UP	GALNT1 LIPJ LGR4 FMNL2 CDKAL1 ENDOU AMPD1 CLIC4 RPA1	3.04e-05	193	213	9	M3534
Coexpression	PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1	STAMBPL1 DUSP6 RASGEF1A LPAR6 ELK3	3.53e-05	46	213	5	M2407
Coexpression	GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN	ACACB MCM6 MIDEAS TIMELESS COX18 PPA1 PREX2 TG ENG	3.87e-05	199	213	9	M5070
Coexpression	GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN	NBN ENOPH1 AP2A2 JMJD6 ABCD3 CLIC4 SLC2A1 TG PRIM2	4.02e-05	200	213	9	M3610
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP	F13A1 IQGAP1 MICU1 DSTYK HAT1 FRY ZNF516 PCNX1 RPA1	4.02e-05	200	213	9	M6090
Coexpression	GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN	ARMCX1 F13A1 ENDOU HACD3 PPA1 MSH6 ENG ALDH7A1 SLC16A10	4.02e-05	200	213	9	M9211
Coexpression	GSE20715_0H_VS_24H_OZONE_LUNG_UP	SLC38A5 NCF4 ARMCX1 FMNL3 ARHGAP1 PACS1 ELK3 ARHGEF2 ALDH7A1	4.02e-05	200	213	9	M4366
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	KIF1B BACH1 FMNL2 RYR3 PTPN13 FRY PCNX4 ST6GALNAC3 ANKRD36	6.32e-05	212	213	9	M39221
Coexpression	DURAND_STROMA_NS_UP	PTPN13 EZR AMPD3 DUSP6 PREX2 SLC16A3 LPAR6 ALDH7A1	7.60e-05	169	213	8	M2582
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	ATR KIF1B NBN MCM6 CDKAL1 MICU1 ABCD3 PPP2R3C RBL1 HAT1 CLIC4 FRYL SLC2A1 MSH6 LNPEP CCT8	8.10e-05	644	213	16	M10501
Coexpression	TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL	BACH1 NBN RPS26 SLC39A8 IQGAP1 CYFIP1 DPYD AMPD3 DUSP6 CLIC4 MSN SPPL2A SLC16A3 PCNX1 ELK3 ENG SLC16A10	9.62e-05	724	213	17	M41700
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	FMNL2 PTK2 CDKAL1 ACSM3 VPS13A ANKIB1 MACC1 CLIC4	1.01e-04	176	213	8	M39223
Coexpression	GSE12505_WT_VS_E2_2_HET_PDC_UP	PANX1 FMNL2 AMPD1 PTPRU PAF1 PCNX1 CDH17	1.01e-04	131	213	7	M437
Coexpression	FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN	PDXDC1 BACH1 NBN ARMCX1 F13A1 SLC39A8 ALMS1 AP2A2 CMKLR2 PPA1 SLC8A1 LPAR6 LTA4H	1.04e-04	458	213	13	M4785
Coexpression	GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP	ATR PTPN13 TMEM41A LIPF FRYL MSN CDH17 SLC16A10	1.09e-04	178	213	8	M8996
Coexpression	ASTIER_INTEGRIN_SIGNALING	ACACB RRAGD USP13 SFTPD MLXIP	1.09e-04	58	213	5	M3590
Coexpression	KASLER_HDAC7_TARGETS_1_UP	ENDOU TMEM41A HACD3 FRYL TG ELK3 ARHGEF2 CDH17	1.84e-04	192	213	8	M2317
Coexpression	DURAND_STROMA_NS_UP	PTPN13 EZR AMPD3 DUSP6 PREX2 SLC16A3 LPAR6 ALDH7A1	1.97e-04	194	213	8	MM962
Coexpression	KASLER_HDAC7_TARGETS_1_UP	ENDOU TMEM41A HACD3 FRYL TG ELK3 ARHGEF2 CDH17	1.97e-04	194	213	8	MM910
Coexpression	FAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL	MYO6 SLC38A5 SLC39A8 IQGAP1 ABCB1 VWF DUSP6 PRXL2A CLIC4 SLC2A1 ENG	2.13e-04	365	213	11	M39018
Coexpression	SENESE_HDAC3_TARGETS_UP	MYO6 BACH1 FMNL2 CDKAL1 IQGAP1 NF1 PLD1 EZR PCDHB15 SF3B1 SLC12A4 PCNX4 ELK3	2.23e-04	495	213	13	M8451
Coexpression	GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	TTC3 ARMCX1 ABCD3 PPA1 FMNL3 AGO1 ALDH7A1 SLC16A10	2.26e-04	198	213	8	M9163
Coexpression	GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP	PTK2 EZR SFTPD HAT1 SLC9A5 CYP4F3 ELK3 SMCR8	2.34e-04	199	213	8	M6260
Coexpression	GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP	NCF4 SLC39A8 AMPD3 CASP5 MSN FMNL3 ANKRD36 ARHGEF2	2.34e-04	199	213	8	M7951
Coexpression	GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN	PANX1 COG3 CDKAL1 NAA25 CLIC4 APOB PPA1 CCT8	2.34e-04	199	213	8	M6507
Coexpression	ZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_DN	MGAT4A TTC3 NDRG3 NT5DC1 ABCB1 VPS13A TMEM181 NEPRO USP13 HACD3 RBL1 RBL2 TLR10 FMNL3 ZFAND1 PACS1 PCNX1 LTA4H RPA1 SLC16A10	2.39e-04	1012	213	20	M40864
Coexpression	GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN	NCF4 NT5DC1 NAA25 CYFIP1 LIPT2 NEPRO COX18 PDCD11	2.42e-04	200	213	8	M9475
Coexpression	GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP	TMEM50A PANX1 RRAGD VPS13A RBL2 DUSP6 SLC9A5 PROS1	2.42e-04	200	213	8	M9478
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	MYO6 F13A1 PTK2 CYFIP1 SRL VWF HACD3 CDH17	2.42e-04	200	213	8	M9496
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN	CELF4 BACH1 PANX1 PTK2 ABCB1 TMEM41A SLC2A1 IMMP2L	2.42e-04	200	213	8	M5975
Coexpression	GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP	HIVEP1 ZFYVE16 TBC1D2B PTK2 ABCB1 ALMS1 MLXIP SLC16A10	2.42e-04	200	213	8	M8030
Coexpression	GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_DN	PANX1 NCF4 NDRG3 F13A1 RRAGD AP2A2 PLD1 MMP12	2.42e-04	200	213	8	M9535
Coexpression	GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	NBN MCM6 ARMCX1 NF1 ABCD3 YARS1 MSH6 ALDH7A1	2.42e-04	200	213	8	M3446
Coexpression	GSE17721_LPS_VS_POLYIC_1H_BMDC_UP	CELF4 ACACB ENDOU ST7 YARS1 PRIM2 AP4M1 ALDH7A1	2.42e-04	200	213	8	M3798
Coexpression	GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_UP	HMCES TIMELESS PPP2R3C GNPAT DUSP6 ARHGAP1 LTA4H PROS1	2.42e-04	200	213	8	M3629
Coexpression	GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN	HMCES TIMELESS PPP2R3C ATP13A1 DUSP6 COX18 PPA1 PIGU	2.42e-04	200	213	8	M3638
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN	BACH1 PANX1 PTK2 ABCB1 MSN LTA4H ELK3 CDH17	2.42e-04	200	213	8	M7150
Coexpression	GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN	ABCB1 TIMELESS MACC1 RBL1 CLIC4 PPA1 ZNF516 ALDH7A1	2.42e-04	200	213	8	M9839
Coexpression	GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN	MGAT4A CD109 BCR ABCB1 CYFIP1 DPYD LRRK1 GSTT1	2.42e-04	200	213	8	M5045
Coexpression	GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN	MIDEAS HMCES AP2A2 EZR LRRK1 MLXIP FMNL3 SNX14	2.42e-04	200	213	8	M7833
Coexpression	GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	TMEM50A ZFYVE16 NCF4 RRAGD GNPAT FRY ZNF516 YLPM1	2.42e-04	200	213	8	M5556
Coexpression	GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP	ARMCX1 F13A1 EZR RBL1 CLIC4 FMNL3 MSH6 FRY	2.42e-04	200	213	8	M9205
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	COG3 TTC3 PDILT ABCD3 APOB PTPRU FMNL3 CDH17	2.42e-04	200	213	8	M9186
Coexpression	GSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_DN	HIVEP1 PTK2 RYR2 ALB CLIC4 FMNL3 GSTT1 SLC8A1	2.42e-04	200	213	8	M6954
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_SST_POS_NEURON_CELL	CELF4 ATP7A PLPPR3 RYR2 ABCB1 NALCN STAMBPL1 TG FRY SLC8A1 SLC16A3	2.68e-04	375	213	11	M45799
Coexpression	GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TREG_CD4_TCELL_DN	SETD1A RPS26 ENOPH1 PTPN13 SYT11 PCDH20 PACS1	2.86e-04	155	213	7	M8944
Coexpression	LU_AGING_BRAIN_UP	IQGAP1 GJA1 PTPN13 ABCD3 VWF RBL2 CLIC4 FRYL MSN	3.19e-04	263	213	9	M5547
Coexpression	KIM_HYPOXIA	BACH1 AMPD3 SLC2A1	3.31e-04	17	213	3	M1496
Coexpression	BURTON_ADIPOGENESIS_PEAK_AT_16HR	SERPINA3 MCM6 HAT1 MSH6	3.39e-04	41	213	4	M1681
CoexpressionAtlas	kidney_adult_RenMedVasc_Tie2_k-means-cluster#3_top-relative-expression-ranked_1000	GINM1 MYO6 FMNL2 SPPL2A LNPEP ST6GALNAC3 PROS1	1.27e-05	80	206	7	gudmap_kidney_adult_RenMedVasc_Tie2_k3_1000
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	MYO6 SLC38A5 MPDZ BCR IQGAP1 ABCB1 ANO2 VWF CLIC4 SLC2A1 PREX2 FRY	3.05e-10	200	216	12	7136936d05ab344a560cf159684c881063b5430d
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	GJA1 ANO2 USP13 VWF DUSP6 PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	4.43e-08	196	216	10	b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCell	mild-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BCR SLC9B1 NAA25 PTPN13 AP2A2 SYT11 USP13 CASP5 YLPM1 NUP133	5.36e-08	200	216	10	ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCell	Ionocyte\|World / Class top	ATP7A GALNT13 IQGAP1 ACSM3 RRAGD PDILT ATP6V1C2 TMEM117 HACD3	1.55e-07	170	216	9	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	FMNL2 PTK2 NALCN WDFY4 PREX2 TLR10 SLC8A1 ZNF516 CDH17	3.03e-07	184	216	9	8e393eea7240584a3cef718bee094e2705ec1891
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 SLC39A8 GALNT13 PTPN13 ABCD3 MACC1 SFTPD LTA4H IMMP2L	3.63e-07	188	216	9	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	F13A1 SLC39A8 AP2A2 DPYD WDFY4 TG ST6GALNAC3 PCNX1 SLC16A10	4.53e-07	193	216	9	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1A MYO6 KIF1B TTC3 IQGAP1 VPS13A FRYL SLC8A1 ZNF516	4.94e-07	195	216	9	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	CD109 GJA1 ANO2 USP13 VWF PREX2 FMNL3 ST6GALNAC3 ENG	4.94e-07	195	216	9	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	MGAT4A ABCB1 ANO2 VWF FRYL PREX2 ST6GALNAC3 ELK3 ENG	4.94e-07	195	216	9	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1A MYO6 KIF1B TTC3 IQGAP1 VPS13A FRYL SLC8A1 ZNF516	4.94e-07	195	216	9	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.16e-07	196	216	9	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.16e-07	196	216	9	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 CYP39A1 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	5.38e-07	197	216	9	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.38e-07	197	216	9	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.38e-07	197	216	9	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 CYP39A1 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	5.85e-07	199	216	9	c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	MGAT4A FMNL2 F13A1 CYFIP1 AP2A2 SLC16A3 LPAR6 ENG SLC16A10	6.10e-07	200	216	9	195862a319794e57f0506757ae45ab70200bc5b4
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 MIDEAS PTPN13 NALCN ALB STAMBPL1 HTRA3 MSH6	1.56e-06	166	216	8	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LGR4 SLC38A5 ADGRV1 ERP27 DPYD ARHGAP1 GABRA4 SLC16A10	1.86e-06	170	216	8	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM6 SLC39A8 ABCD3 ATP6V1C2 ANO2 MACC1 HACD3 SFTPD	1.86e-06	170	216	8	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERP27 SRL ATP6V1C2 TMEM117 AMPD3 RHBG GALNT17 PCNX4	2.52e-06	177	216	8	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MGAT4A CD109 ABCB1 ANO2 VWF PREX2 ST6GALNAC3 ELK3	3.23e-06	183	216	8	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELF4 L2HGDH MCM6 SRL TRPT1 RBL1 LIPF CLIC4	3.50e-06	185	216	8	b4af9ae4c358b48357cb135b740266e1652d886a
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	BCR PTK2 ABCB1 ANO2 VWF CLIC4 PREX2 ST6GALNAC3	3.50e-06	185	216	8	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADGRV1 SLC39A8 GALNT13 PTPN13 ABCD3 MACC1 SFTPD LTA4H	3.64e-06	186	216	8	e83718fabb057100835d3357df407f283d23fe16
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	3.78e-06	187	216	8	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIF1B F13A1 CDKAL1 XPO4 MLXIP MSH6 SLC12A4 ANKRD36	4.26e-06	190	216	8	651a1d3ae286e40f9d9f60e438211c6148d24143
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	MGAT4A CD109 ABCB1 ANO2 VWF PREX2 ST6GALNAC3 ELK3	4.26e-06	190	216	8	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 SYT11 ANO2 VWF PREX2 ST6GALNAC3 ENG	4.42e-06	191	216	8	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	CD109 GJA1 USP13 VWF CLIC4 PREX2 FMNL3 ST6GALNAC3	4.42e-06	191	216	8	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ABCB1 ANO2 VWF CLIC4 MSN ST6GALNAC3 ENG	4.60e-06	192	216	8	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	4.60e-06	192	216	8	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	4.60e-06	192	216	8	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ACACB RYR2 SRL USP13 ST7 FRY SLC8A1 GALNT17	4.60e-06	192	216	8	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 CYP39A1 ABCB1 VWF SLC2A1 PREX2 FRY ENG	4.78e-06	193	216	8	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FMNL2 CDKAL1 DPYD TG SLC8A1 PCNX1 IMMP2L SLC16A10	4.78e-06	193	216	8	779276e775cb2492e8dd36436295a536084a6415
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	ABCB1 ANO2 VWF FRYL PREX2 ST6GALNAC3 ELK3 ENG	4.78e-06	193	216	8	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERP27 ATP6V1C2 TMEM117 RHBG SLC8A1 GALNT17 PCNX4	4.84e-06	137	216	7	81cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR2 ABCB1 ANO2 VWF PREX2 ST6GALNAC3 ELK3	4.96e-06	194	216	8	a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	ABCB1 ANO2 VWF FRYL PREX2 ST6GALNAC3 ELK3 ENG	4.96e-06	194	216	8	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	CD109 ABCB1 NOS1 ANO2 VWF PREX2 ST6GALNAC3 ENG	4.96e-06	194	216	8	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	MGAT4A ABCB1 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	5.15e-06	195	216	8	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	MGAT4A FMNL2 F13A1 AP2A2 DPYD WDFY4 SLC8A1 SLC16A10	5.15e-06	195	216	8	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	MGAT4A ANO2 VWF FRYL PREX2 ST6GALNAC3 ELK3 ENG	5.15e-06	195	216	8	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 RYR3 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	5.15e-06	195	216	8	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GJA1 ANO2 VWF CLIC4 PREX2 MSN ST6GALNAC3 ENG	5.15e-06	195	216	8	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	KIF1B NCF4 BPI RRAGD AMPD3 HTRA3 LTA4H CYP4F3	5.15e-06	195	216	8	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD109 NOS1 ANO2 VWF CLIC4 PREX2 ELK3 ENG	5.15e-06	195	216	8	81a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCell	LV-09._Endothelium_I\|LV / Chamber and Cluster_Paper	ABCB1 ANO2 VWF FRYL PREX2 ST6GALNAC3 ELK3 ENG	5.55e-06	197	216	8	f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD109 ABCB1 ANO2 VWF PREX2 MSN ST6GALNAC3 ENG	5.55e-06	197	216	8	31bec97c3952c48031bd66a5dad16a70a61519c3
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CD109 FMNL2 F13A1 AP2A2 AMPD3 SLC8A1 LPAR6 SLC16A10	5.55e-06	197	216	8	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CD109 FMNL2 F13A1 AP2A2 AMPD3 SLC8A1 LPAR6 SLC16A10	5.55e-06	197	216	8	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD109 ABCB1 GJA1 ANO2 VWF PREX2 ST6GALNAC3 ENG	5.76e-06	198	216	8	5c82dad416938d5c460069796d808170e7dbc8d9
ToppCell	Tracheal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCB1 GJA1 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	5.76e-06	198	216	8	77e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.76e-06	198	216	8	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 GJA1 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.76e-06	198	216	8	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	metastatic_Brain-Endothelial_cells-Tumor_ECs\|metastatic_Brain / Location, Cell class and cell subclass	SLC38A5 ABCB1 GJA1 ANO2 VWF FRY ST6GALNAC3 ENG	5.76e-06	198	216	8	5e274f29cc796dae7d64d6035e904816c25f9914
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	5.76e-06	198	216	8	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.76e-06	198	216	8	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	5.76e-06	198	216	8	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	metastatic_Brain-Endothelial_cells\|metastatic_Brain / Location, Cell class and cell subclass	SLC38A5 ABCB1 GJA1 ANO2 VWF FRY ST6GALNAC3 ENG	5.76e-06	198	216	8	97ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRV1 PTK2 CDKAL1 PTPN13 NF1 DPYD ST7 IMMP2L	5.76e-06	198	216	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	FMNL2 PTK2 CDKAL1 NF1 TMEM117 DPYD PACS1 IMMP2L	5.98e-06	199	216	8	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	CD109 FMNL2 F13A1 AP2A2 DPYD AMPD3 SLC8A1 SLC16A10	5.98e-06	199	216	8	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	6.21e-06	200	216	8	86ec951234015ced7126b016199e5869a0f22478
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	6.21e-06	200	216	8	c239e6f5d23caa9a59b83e9b352b2d6a691dcb28
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	KIF1B NCF4 BPI RRAGD AMPD3 DUSP6 LTA4H CYP4F3	6.21e-06	200	216	8	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC38A5 ABCB1 VWF PRXL2A SLC2A1 PREX2 FRY ENG	6.21e-06	200	216	8	061ba851f941c616ddb462512e826c412881c3ce
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	CD109 GJA1 A2ML1 TMEM117 SLC2A1 CYP4F3 ELK3	1.13e-05	156	216	7	ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	L2HGDH MCM6 RRAGD TIMELESS PPA1 YARS1 RPA1	1.28e-05	159	216	7	e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	CD109 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	1.34e-05	160	216	7	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LGR4 RYR3 IQGAP1 DNAH6 NOS1 EZR CASR	1.45e-05	162	216	7	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA1 ANO2 VWF PREX2 ST6GALNAC3 ELK3 ENG	1.51e-05	163	216	7	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ENDOU NOS1 ANO2 VWF PREX2 ST6GALNAC3 ENG	1.57e-05	164	216	7	3cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MCM6 GJA1 VWF HTRA3 PREX2 ELK3 ENG	1.83e-05	168	216	7	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CD109 NOS1 ANO2 VWF PCDHB15 PREX2 ENG	1.90e-05	169	216	7	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	Ionocyte-iono-1\|World / Class top	GALNT13 IQGAP1 RRAGD PDILT TMEM117 HACD3 RASGEF1A	1.90e-05	169	216	7	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LGR4 AP2A2 TMEM117 DMGDH ST6GALNAC3 ENG SLC16A10	2.05e-05	171	216	7	7c8304573b892ef9ea4e048cba9ea9fbab848dcd
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCB1 SRL NOS1 ANO2 VWF PREX2 ST6GALNAC3	2.05e-05	171	216	7	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM6 URB1 SCO1 TIMELESS GPR33 RBL1 XPO4	2.21e-05	173	216	7	15af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCell	Ionocyte-iono-2\|World / Class top	ATP7A NDRG3 GALNT13 IQGAP1 ACSM3 RRAGD TMEM117	2.21e-05	173	216	7	e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA1 ERP27 CMKLR2 ANO2 VWF SLC16A3 ELK3	2.30e-05	174	216	7	4a18b51501eaaeb7907e99316ba8ae15b2c7d529
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENDOU PCDH20 MSN FMNL3 ST6GALNAC3 ENG PROS1	2.47e-05	176	216	7	eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD109 FMNL2 PTPN13 PLD1 AMPD3 SFTPD LNPEP	2.47e-05	176	216	7	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho\|lymph-node_spleen / Manually curated celltypes from each tissue	TTC21A ADGRV1 RYR3 PLD1 PIGU SPPL2A CDH17	2.56e-05	177	216	7	53040dbeb18574a48e352e4bce252c7c3018762c
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACACB ANO2 VWF FRYL PREX2 ST6GALNAC3 ENG	2.75e-05	179	216	7	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENDOU PCDH20 PREX2 FMNL3 ST6GALNAC3 ENG PROS1	3.06e-05	182	216	7	ab5761bf9af439231cd0f487b6467e372672a517
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC39A8 GALNT13 PTPN13 ABCD3 MACC1 SFTPD LTA4H	3.06e-05	182	216	7	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENDOU PCDH20 PREX2 FMNL3 ST6GALNAC3 ENG PROS1	3.06e-05	182	216	7	3b4dbf61ca0fe50efe05449815630e301cb76630
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC38A5 ABCB1 ANO2 VWF CLIC4 SLC2A1 ENG	3.17e-05	183	216	7	c7fc96ac1d5d31ccefe0c1fc6ec76c7d8607a172
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic\|GI_small-bowel / Manually curated celltypes from each tissue	PTK2 WDFY4 PREX2 TLR10 SLC8A1 ZNF516 CDH17	3.17e-05	183	216	7	6109199cf25b28831193a5ed7925b5bf38c6eb43
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC38A5 ABCB1 ANO2 VWF CLIC4 SLC2A1 ENG	3.17e-05	183	216	7	6cdadb3ece45a94a2915063aa461048e1d371ccd
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	ANO2 VWF PREX2 FMNL3 ST6GALNAC3 ELK3 ENG	3.17e-05	183	216	7	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC38A5 ABCB1 ANO2 VWF CLIC4 SLC2A1 ENG	3.17e-05	183	216	7	8714d3e7663c93cdf9b25b647353572e136f30c3
Drug	hydroxyl radicals	ATP7A SLC38A5 L2HGDH NCF4 CYP39A1 ENOPH1 PTK2 ABCB1 PTPN13 AP2A2 TIMELESS ALB ATP6V1C2 PLD1 MMP12 NOS1 DMGDH DPYD AMPD1 USP13 AMPD3 VWF DUSP6 LIPF PPA1 PTPRU PIGU GSTT1 USP5 LTA4H AP4M1 ALDH7A1 PROS1	4.22e-07	1341	215	33	CID000000961
Drug	NOC-9	PTK2 GJA1 APOB SLC12A4 ALDH7A1	1.29e-06	21	215	5	CID000004524
Drug	Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; MCF7; HT_HG-U133A	TMEM104 CDKAL1 NF1 NOS1 AMPD3 RBL1 RBL2 CASR SLC1A7 PACS1 ALDH7A1	3.05e-06	198	215	11	7322_UP
Drug	Thimerosal	ACACB KIF1A MYO6 PLPPR3 ADGRV1 COG3 CYP39A1 FMNL2 PTK2 RYR3 IQGAP1 NF1 SRL ALB HAT1 RASGEF1A SLC2A1 PREX2 MSN GSTT1 SLC8A1 AGO1 SF3B1 LNPEP FER1L4 PRIM2 PCNX1 LTA4H	9.33e-06	1199	215	28	ctd:D013849
Drug	Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; HL60; HG-U133A	HIVEP1 ATR ALMS1 AMPD3 ST7 MSH6 USP5 LPAR6 YLPM1 ELK3	1.45e-05	191	215	10	1418_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A	SETD1A TBC1D2B NBN PTK2 CDKAL1 RYR2 NF1 TIMELESS PACS1 SLC16A3	1.66e-05	194	215	10	4727_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	ACACB MGAT4A NBN IQGAP1 ALMS1 DPYD RBL2 SF3B1 SLC16A3 PCNX4	1.74e-05	195	215	10	6918_UP
Drug	Papaverine hydrochloride [61-25-6]; Up 200; 10.6uM; PC3; HT_HG-U133A	KIF1A TBC1D2B ARMCX1 URB1 ACSM3 TIMELESS PLD1 MLXIP TG SLC12A4	1.82e-05	196	215	10	5769_UP
Drug	Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; MCF7; HT_HG-U133A	NCF4 URB1 NF1 SFTPD DUSP6 LRRK1 FRY SLC12A4 SLC16A3 PCNX1	1.90e-05	197	215	10	4408_UP
Drug	Ungerine nitrate; Down 200; 10.2uM; HL60; HT_HG-U133A	KIF1B MGAT4A TBC1D2B BCR AP2A2 PLD1 ST7 AGPAT2 LRRK1 AP4M1	1.90e-05	197	215	10	2514_DN
Drug	fluo-3	RYR2 RYR3 ABCB1 GJA1 HACD3 CASR LPAR6 ENG	2.13e-05	122	215	8	CID000104978
Drug	folate polyglutamate	NCF4 ENOPH1 TIMELESS ALB NOS1 DMGDH VWF CASR APOB PROS1	2.67e-05	205	215	10	CID000003405
Drug	Sy 2	NBN BCR SCO1	2.83e-05	7	215	3	CID000022260
Disease	Malignant neoplasm of breast	CD109 NBN COG3 TTC3 ABCB1 GJA1 NAA25 NF1 JMJD6 TIMELESS DPYD VWF PCDHB15 PPA1 PCDH20 SLC2A1 MSH6 SLC16A3 NUP133 ELK3 GABRA4	2.26e-05	1074	206	21	C0006142
Disease	acute lymphoblastic leukemia (is_implicated_in)	NBN BCR ABCB1 DPYD GSTT1	4.14e-05	55	206	5	DOID:9952 (is_implicated_in)
Disease	Adenosine monophosphate deaminase deficiency	AMPD1 AMPD3	4.85e-05	2	206	2	C2931781
Disease	Muscle AMP deaminase deficiency	AMPD1 AMPD3	4.85e-05	2	206	2	C0268123
Disease	level of collagen alpha-1(X) chain in blood serum	NT5DC1 COL10A1	4.85e-05	2	206	2	OBA_2041080
Disease	Developmental Disabilities	SETD1A KIF1A WDFY4 SLC2A1	5.48e-05	30	206	4	C0008073
Disease	cutaneous melanoma, hair color	ADGRV1 BCR DSTYK AMPD3 PIGU	7.40e-05	62	206	5	EFO_0000389, EFO_0003924
Disease	Myoclonic Seizures	ATP7A MPDZ NOS1 PIGU SLC2A1 SLC8A1	9.25e-05	104	206	6	C4317123
Disease	Colorectal Carcinoma	CD109 ABCB1 NF1 PDILT VPS13A ABCD3 DPYD AMPD1 HAT1 APOB PTPRU SLC1A7 PREX2 MSH6 PROS1	1.34e-04	702	206	15	C0009402
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	1.45e-04	3	206	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	1.45e-04	3	206	2	DOID:8545 (implicated_via_orthology)
Disease	Ataxia, Motor	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0278161
Disease	Tremor, Rubral	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0750940
Disease	Ataxia, Appendicular	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0750937
Disease	Ataxia, Sensory	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0240991
Disease	Abnormal coordination	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0520966
Disease	Ataxia, Truncal	ATP7A SLC2A1 GABRA4	1.76e-04	16	206	3	C0427190
Disease	X-12125 measurement	ALMS1 AGXT2	2.88e-04	4	206	2	EFO_0800707
Disease	synucleinopathy (biomarker_via_orthology)	KIF1A KIF1B	2.88e-04	4	206	2	DOID:0050890 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	KIF1B RYR3 ABCB1 PTPN13 ALB GSTT1 SF3B1	2.94e-04	181	206	7	DOID:684 (is_implicated_in)
Disease	Liver Cirrhosis, Experimental	ZFYVE16 BCR ARMCX1 SLC39A8 IQGAP1 ABCB1 GJA1 ALB EZR VWF RBL2 DUSP6 MSN FRY LTA4H	3.80e-04	774	206	15	C0023893
Disease	Profound Mental Retardation	L2HGDH NF1 SLC2A1 SNX14 FRY AP4M1	4.48e-04	139	206	6	C0020796
Disease	Mental deficiency	L2HGDH NF1 SLC2A1 SNX14 FRY AP4M1	4.48e-04	139	206	6	C0917816
Disease	Mental Retardation, Psychosocial	L2HGDH NF1 SLC2A1 SNX14 FRY AP4M1	4.48e-04	139	206	6	C0025363
Disease	urethral obstruction (biomarker_via_orthology)	GJA1 NOS1	4.78e-04	5	206	2	DOID:12577 (biomarker_via_orthology)
Disease	secondary hyperparathyroidism (is_marker_for)	CASR ENG	4.78e-04	5	206	2	DOID:12466 (is_marker_for)
Disease	pontocerebellar hypoplasia (implicated_via_orthology)	AMPD1 AMPD3	4.78e-04	5	206	2	DOID:0060264 (implicated_via_orthology)
Disease	obsolete_red blood cell distribution width	ATR BACH1 MCM6 MIDEAS PTK2 SLC39A8 IQGAP1 ABCB1 MICU1 CYFIP1 DSTYK VPS13A PLD1 RBL1 APOB SERPINA2 SLC2A1 ZNF516 YLPM1 SMCR8 SLC16A10	5.15e-04	1347	206	21	EFO_0005192
Disease	nervous system disorder	ABCB1 NOS1 DPYD SLC2A1	5.17e-04	53	206	4	C0027765
Disease	Autistic Disorder	KIF1A GJA1 NF1 DPYD WDFY4 AGO1 IMMP2L GABRA4	5.24e-04	261	206	8	C0004352
Disease	urate measurement	LGR4 MCM6 ADGRV1 SLC39A8 CDKAL1 NAA25 ACSM3 RRAGD SYT11 PDILT PRXL2A MLXIP PIGU ORC4 SPPL2A SLC16A10	5.86e-04	895	206	16	EFO_0004531
Disease	Liver Failure, Acute	PANX1 SCO1 ALB	6.09e-04	24	206	3	C0162557
Disease	Ataxia	ATP7A SLC2A1 GABRA4	6.89e-04	25	206	3	C0004134
Disease	coronary artery disease (is_implicated_in)	MMP12 AMPD1 APOB AGXT2 GSTT1	6.95e-04	100	206	5	DOID:3393 (is_implicated_in)
Disease	Idiopathic generalized epilepsy	CASR SLC2A1	7.14e-04	6	206	2	C0270850
Disease	familial combined hyperlipidemia (is_marker_for)	VWF APOB	7.14e-04	6	206	2	DOID:13809 (is_marker_for)
Disease	AIDS dementia	NALCN SLC8A1	7.14e-04	6	206	2	EFO_0002608
Disease	Generalized seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0234533
Disease	Clonic Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0234535
Disease	Non-epileptic convulsion	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0751056
Disease	Atonic Absence Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0751123
Disease	Single Seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0751110
Disease	Visual seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0270824
Disease	Epileptic drop attack	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0270846
Disease	Vertiginous seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0422855
Disease	Gustatory seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0422854
Disease	Seizures, Somatosensory	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0422850
Disease	Olfactory seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0422853
Disease	Seizures, Auditory	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0422852
Disease	Convulsive Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0751494
Disease	Seizures, Sensory	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0751496
Disease	Complex partial seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0149958
Disease	Nonepileptic Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C3495874
Disease	Generalized Absence Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C4505436
Disease	Jacksonian Seizure	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C0022333
Disease	gastroesophageal reflux disease	CELF4 SLC39A8 DPYD APOB YLPM1	7.27e-04	101	206	5	EFO_0003948
Disease	Epileptic Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.27e-04	101	206	5	C4317109
Disease	Absence Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.60e-04	102	206	5	C4316903
Disease	Convulsions	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.60e-04	102	206	5	C4048158
Disease	Tonic Seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	7.60e-04	102	206	5	C0270844
Disease	brain ischemia (biomarker_via_orthology)	ABCB1 GJA1 NOS1 DUSP6 SLC8A1	7.60e-04	102	206	5	DOID:2316 (biomarker_via_orthology)
Disease	schizophrenia, intelligence, self reported educational attainment	PDXDC1 CELF4 RPS26 SLC39A8 DPYD HAT1 SF3B1 PCNX1 IMMP2L	7.74e-04	346	206	9	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	Tonic - clonic seizures	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	8.30e-04	104	206	5	C0494475
Disease	Seizures, Focal	ATP7A MPDZ NOS1 SLC2A1 SLC8A1	8.30e-04	104	206	5	C0751495
Disease	cystic fibrosis (is_implicated_in)	SERPINA3 NOS1 GSTT1	8.67e-04	27	206	3	DOID:1485 (is_implicated_in)
Disease	myeloid white cell count	KIF1B MCM6 FMNL2 CDKAL1 GJA1 BPI DSTYK AMPD3 ATP13A1 LRRK1 SLC2A1 PREX2 GALNT17 SPPL2A LNPEP ZNF516	9.51e-04	937	206	16	EFO_0007988
Disease	hereditary spastic paraplegia (is_implicated_in)	KIF1A L2HGDH	9.95e-04	7	206	2	DOID:2476 (is_implicated_in)
Disease	triglycerides to total lipids in IDL percentage	PDXDC1 SLC39A8 DMGDH APOB	9.96e-04	63	206	4	EFO_0022329
Disease	Depressive disorder	ABCB1 TIMELESS ALB NOS1 DUSP6 TG GSTT1 LTA4H	1.02e-03	289	206	8	C0011581
Disease	Child Development Disorders, Specific	KIF1A WDFY4 SLC2A1	1.07e-03	29	206	3	C0085997
Disease	Child Development Deviations	KIF1A WDFY4 SLC2A1	1.07e-03	29	206	3	C0085996
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	HIVEP1 SLC39A8 PDILT DPYD AMPD3 DUSP6 PACS1 YLPM1 RPA1	1.10e-03	364	206	9	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	hypertension (biomarker_via_orthology)	PTK2 GJA1 NOS1 VWF SLC2A1 SLC8A1 ENG	1.13e-03	227	206	7	DOID:10763 (biomarker_via_orthology)
Disease	Myopathy	MICU1 ALB AMPD1	1.18e-03	30	206	3	C0026848
Disease	Crohn's disease (is_implicated_in)	ABCB1 BPI GSTT1	1.18e-03	30	206	3	DOID:8778 (is_implicated_in)
Disease	serum alanine aminotransferase measurement	BACH1 L2HGDH PANX1 RPS26 SLC39A8 GALNT13 ABCB1 NAA25 DSTYK EZR APOB MLXIP SERPINA2 PIGU ST6GALNAC3	1.23e-03	869	206	15	EFO_0004735
Disease	Intellectual Disability	SETD1A L2HGDH NF1 PIGU SLC2A1 PACS1 SNX14 FRY AGO1 AP4M1	1.26e-03	447	206	10	C3714756
Disease	arteriosclerosis (is_implicated_in)	F13A1 MMP12 APOB	1.31e-03	31	206	3	DOID:2349 (is_implicated_in)
Disease	temporal lobe epilepsy (biomarker_via_orthology)	ABCB1 CYFIP1 NOS1	1.31e-03	31	206	3	DOID:3328 (biomarker_via_orthology)
Disease	familial hyperlipidemia (is_implicated_in)	ABCB1 APOB	1.32e-03	8	206	2	DOID:1168 (is_implicated_in)
Disease	LEUKEMIA, ACUTE LYMPHOBLASTIC	NBN BCR	1.32e-03	8	206	2	613065
Disease	Uveal melanoma	JMJD6 SF3B1	1.32e-03	8	206	2	C0220633
Disease	Acute lymphoid leukemia	NBN BCR	1.32e-03	8	206	2	cv:C0023449
Disease	N2,N2-dimethylguanosine measurement	ALMS1 AGXT2	1.32e-03	8	206	2	EFO_0021125
Disease	Thrombophilia due to thrombin defect	F13A1 PROS1	1.32e-03	8	206	2	cv:C3160733
Disease	blood urea nitrogen measurement	PLPPR3 MCM6 ADGRV1 NAA25 PDILT PRXL2A MLXIP PIGU SLC1A7 SLC16A3	1.37e-03	452	206	10	EFO_0004741
Disease	cholesteryl esters to total lipids in very small VLDL percentage	PDXDC1 SLC39A8 DMGDH APOB	1.56e-03	71	206	4	EFO_0022259
Disease	alpha-1-antitrypsin measurement	SERPINA3 SERPINA2	1.69e-03	9	206	2	EFO_0008327
Disease	symmetrical dimethylarginine measurement	AGXT2 ST6GALNAC3	1.69e-03	9	206	2	EFO_0006523
Disease	thoracic aortic calcification measurement	CDKAL1 VPS13A	1.69e-03	9	206	2	EFO_0010273
Disease	free cholesterol to total lipids in large LDL percentage	PDXDC1 SLC39A8 DMGDH APOB	1.81e-03	74	206	4	EFO_0022280
Disease	Borderline personality disorder	DPYD PRXL2A METTL21C	1.86e-03	35	206	3	HP_0012076
Disease	lung squamous cell carcinoma (is_marker_for)	PTK2 PTPN13 PREX2	2.02e-03	36	206	3	DOID:3907 (is_marker_for)
Disease	Cardiovascular Diseases	ALB VWF APOB	2.02e-03	36	206	3	C0007222
Disease	metabolite measurement	PDXDC1 SETD1A MCM6 CDKAL1 MICU1 ALMS1 DMGDH LIPF WDFY4 AGXT2 YLPM1	2.05e-03	560	206	11	EFO_0004725
Disease	Malignant Neoplasms	ATR ABCB1 DPYD GSTT1 SF3B1	2.09e-03	128	206	5	C0006826
Disease	diabetes mellitus biomarker	CDKAL1 RASGRF1	2.10e-03	10	206	2	EFO_0006842
Disease	2-ketocaprylate measurement	ALMS1 PCNX4	2.10e-03	10	206	2	EFO_0800110
Disease	Glioblastoma	PTK2 NF1 DUSP6 GSTT1	2.30e-03	79	206	4	C0017636
Disease	pulmonary hypertension (biomarker_via_orthology)	RYR2 RYR3 GJA1 CASR	2.41e-03	80	206	4	DOID:6432 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LTFSVDYNFPKKALV	SYT11	161	Q9BT88
VQYPKGFLKEAFELV	AGXT2	296	Q9BYV1
VKGFEPLIQFAYTAK	BACH1	81	O14867
FFLLEKILTKYGVDP	AADACL2	166	Q6P093
IFAKFSAYIKNSRPE	CLIC4	121	Q9Y696
TPYKDIFAAFNTKFI	COX18	316	Q8N8Q8
PELLFFAKRYKAAFT	ALB	176	P02768
FAFSLYKQLVLKAPD	SERPINA3	56	P01011
TETFAPILYVFKFKN	ALDH7A1	426	P49419
IFFKVPELYEIHKEF	BCR	546	P11274
CIFFNKIYIILFKPS	CASR	851	P41180
VFLQEKDQKYIFPTL	ARHGEF2	501	Q92974
YDALEKKQFLPVAFP	ATP13A1	181	Q9HD20
PTLYLFVGENFKKVF	GPR33	296	Q49SQ1
FGTFSVEEYVLPKFK	A2ML1	206	A8K2U0
TVGKPIKLLANYFEV	AGO1	31	Q9UL18
YGIFIFSEKNRPVKV	ADGRV1	1976	Q8WXG9
SSFGEKPIVIYKQAF	ALMS1	1476	Q8TCU4
IFELFAKNFSYGKPL	CMTR2	26	Q8IYT2
YGFFLEPKSTKKEIF	ANKIB1	666	Q9P2G1
QGFYTSKDFLPLVAK	DPYD	301	Q12882
YLLDRFAQPVTKDKF	ANKRD36	401	A6QL64
FLEYAKNPFLDFLQK	AMPD1	626	P23109
KAFLLKFVNAYSPIF	ANO2	626	Q9NQ90
EYSFKIFPEKNIRGF	ENG	276	P17813
LSTYIKFVNLFPEVK	AP2A2	541	O94973
IYDIFRSKKLLPNFG	AMPD3	476	Q01432
FILSSKGDPLIYKDF	AP4M1	6	O00189
KLSGYFVPFIVFVSI	ATP7A	936	Q04656
VYLAKLGNFFSPKVV	IQGAP1	76	P46940
YIKAFCKGFFVAVPV	IMMP2L	11	Q96T52
FVKKIDAAVFNPRFY	MMP12	376	P39900
LPFVLKPTFKNFYAL	PCDHB18P	336	Q96TA0
PEIFLGFLKAYVEKF	LTA4H	401	P09960
AAYEIFKIIDNKPSI	ABCB1	361	P08183
FFFFLDPLRTGKIKI	PPP2R3C	226	Q969Q6
FTVSAVIFKKYEPIF	RBL2	156	Q08999
VIFKKYEPIFQDIFK	RBL2	161	Q08999
ITFLIAQEKEFPKFF	ACACB	1461	O00763
FGFPQYVKIFKEQLS	ORC4	221	O43929
YVKIFKEQLSLPAEF	ORC4	226	O43929
DKYFKQLQVVPLFGD	CYFIP1	296	Q7L576
ITPIAGDYILFKFDK	MGAT4A	421	Q9UM21
GDYILFKFDKPVNVE	MGAT4A	426	Q9UM21
VVQPGKLTEAFKYFL	NDRG3	296	Q9UGV2
LGSLKSNPYFEFVLK	NUP133	1131	Q8WUM0
IAFFTIRDPEGKYKV	PCDH20	451	Q8N6Y1
RKEIPLAKDFYVAFQ	MCM6	101	Q14566
KVPKFFTDDLFQYAG	JMJD6	151	Q6NYC1
PLIYNSFAQFLVKEK	NT5DC1	31	Q5TFE4
YPVKIKVRFSFFLQI	HACD3	316	Q9P035
LVLFFIFTYFKVPET	SLC2A1	441	P11166
CFLGATVKYLQKFIP	L2HGDH	376	Q9H9P8
YAFPKAVSVFFKELI	SLC16A3	36	O15427
YFQFLAKFEIALPVA	LRRK1	971	Q38SD2
KYAPIFESDFIQITK	GARIN4	41	Q8IYT1
ITILKVFFPVSEYKG	GINM1	281	Q9NU53
VDYIKTKPIVFEVFG	KIF1B	1181	O60333
IKIFFALAPVFSTKY	LIPJ	161	Q5W064
KFKGSFLIYPESEAV	FER1L4	1216	A9Z1Z3
KIFRYFATLKVISEP	MICU1	126	Q9BPX6
FVPQSLFKFIFGDKI	LIPF	216	P07098
SQFIGYPITLFVEKK	HSP90AA5P	41	Q58FG0
KFKLYGITFTNPLVF	PCNX1	1096	Q96RV3
YKQDFFLKRFPQTVL	PCNX4	11	Q63HM2
PIKSLDKFLAVFYSV	OR4F5	256	Q8NH21
FVVDGFNVLYNKKPV	PDXDC1	161	Q6P996
EKLFSKPTYAAFINL	ENDOU	191	P21128
KPGEYVIKSLFAEFA	FRYL	11	O94915
TGIFPLSFVKILKDF	NCF4	216	Q15080
ANITFYTGVPKAEFK	F13A1	556	P00488
FDEPAFKATFIIKII	LNPEP	306	Q9UIQ6
LNPVLYVFFNPKFKE	LGR4	796	Q9BXB1
LLFKFRAKFYPEDVS	MSN	76	P26038
SKIDKYARILFPVTF	GABRA4	516	P48169
LFTPAVLEKYNVVFK	TUBGCP4	466	Q9UGJ1
SVDRFLAIVYPFKSK	LPAR6	111	P43657
PKLKTVLFVVFFAIY	OR5K3	21	A6NET4
PIKSLDKFLAVFYSV	OR4F17	256	Q8NGA8
FVPFRQKTDVLKVYE	PANX1	296	Q96RD7
FKLKPSVENFYRLVT	PCDHB15	391	Q9Y5E8
ETITFLYKFIKGACP	MSH6	1281	P52701
NVFFYTIPLAIKLKE	PIGU	296	Q9H490
VFFFKVPKLGSEIID	DSTYK	276	Q6XUX3
SYQKFIPFIGVVKVG	PACS1	741	Q6VY07
KGQLFPLAKEFIDQY	NOS1	356	P29475
VDVFFAAKTLRNYKP	PTPRU	1406	Q92729
FKDFFYIISPGVVKV	GALNT13	376	Q8IUC8
KFKQVFDTTLLAEYP	METTL21C	236	Q5VZV1
LQYPSIVTKAFVFKA	OR56B4	136	Q8NH76
LKLGFESIYKIPFAD	PRIM2	176	P49643
IFSIIIKPLFESFKG	MLXIP	836	Q9HAP2
QFVAYFLPVEETLKK	PAF1	256	Q8N7H5
QVDKFFPLIEVNKVY	RPA1	241	P27694
EFKNFFYIISPGVTK	GALNT1	376	Q10472
FVKDILFPYIEENVK	ENOPH1	26	Q9UHY7
KEYITNFPLFIGKVV	SERPINA2	401	P20848
VEKPQEFTIVAFVKY	APOB	2046	P04114
GYSFSIPVKVLADKF	APOB	3716	P04114
SKLIKTLFPFEAEAY	ATR	296	Q13535
VKFRIVTLFSDFKPY	CD109	146	Q6YHK3
FVFDLPLQVKIKTFY	CEFIP	1286	Q711Q0
YFLNKPIIFGDFIKF	DNAH6	2366	Q9C0G6
PRYKFNFIADVVEKI	HTRA3	136	P83110
FLSLLEKEVDFKPFG	HAT1	126	O14929
KKPDVLLYDTIFQIF	CASP5	281	P51878
YFFITKKNPIVFIRG	SLC1A7	316	O00341
GLFKPFVESYQIICK	GNPAT	571	O15228
ETVKLVEEYKFPSLF	CDKAL1	376	Q5VV42
YLSNKDTEFILFKPV	COG3	771	Q96JB2
FIALTVKEKYPDLAN	FMNL3	811	Q8IVF7
TKFFGTFLPEVAKKF	BPI	326	P17213
IELFYVFFKGVKDRV	GJA1	226	P17302
KYSKDLPQISIIFIF	GALNT17	146	Q6IS24
FPVFVRFVKAYKQAE	FMNL2	971	Q96PY5
IGQKFVYKFVSFPEI	ELK3	76	P41970
ILVKYPTFQDKTLNF	MACC1	536	Q6ZN28
GLEYFVKLNKPADFI	DMGDH	741	Q9UI17
FNKGIAIYKKDFFLV	MIDEAS	841	Q6PJG2
APFSLEYRVFLKNEK	PPA1	11	Q15181
KKGDLFIFFDIQFPT	DNAJB13	286	P59910
FFKLKESQLPALAIY	ERP27	211	Q96DN0
KTGFEIGFLVLFYKL	GJB7	131	Q6PEY0
EFIEKARIKYGPIFT	CYP39A1	51	Q9NYL5
LFAPAAIVPKDKVFY	CYP4F3	111	Q08477
LQFKFRAKFYPEDVA	EZR	76	P15311
KPGEYVLKSLFVNFT	FRY	61	Q5TBA9
GYVIIKKPLDFETAA	CDH17	511	Q12864
LFENAGEFKYKQIPI	DUSP6	246	Q16828
GIEKAFLFDVVSKIY	RRAGD	256	Q9NQL2
EAIANYVKEFSPKLV	SCO1	211	O75880
YEQEIKFFAKVVLPL	RYR2	2956	Q92736
KFFAKVVLPLIDQYF	RYR2	2961	Q92736
FIYFPQIKTEKSGSI	HMCES	141	Q96FZ2
KSFIEYIKSQPIVFE	KIF1A	1061	Q12756
PFLVAFKEIYKCTLI	LIPT2	211	A6NK58
LLPFKKGAFYLAVQA	AGPAT2	181	O15120
SFIKIPVGKEEFVYI	PTPN13	2266	Q12923
PIKSLDKFLAVFYSV	OR4F4	256	Q96R69
QEFGITKAPELKLFF	PDILT	111	Q8N807
AVYIFAKKNDIPFEL	GSTT1	16	P30711
FVKIANFSYPLFLKL	TAS2R39	136	P59534
LSYNTKFAIPDFKVG	ATP6V1C2	31	Q8NEY4
AIAFLTLGYFFKIKE	TMEM248	31	Q9NWD8
IDQRKIFTFAEKYLP	YARS1	186	P54577
FGKQLVVSYFPDKVA	TMEM41A	126	Q96HV5
AKEKDIVYPGIAVFF	TMEM50A	121	O95807
IEKSYKSIFVLSPNF	TLR10	686	Q9BXR5
IVKPEYFTEFLKAVE	NBN	171	O60934
ELKKIRGFLVQFPFY	PLD1	1036	Q13393
VSTVIFKKYEPIFLD	RBL1	131	P28749
FKKYEPIFLDIFQNP	RBL1	136	P28749
LFFLVSVIYKKFQLG	SLC38A5	206	Q8WUX1
LKFFEILSPVYRFDK	PTK2	241	Q05397
ITEFLGQPYFEAFKK	NEPRO	226	Q6NW34
PLISFKFGQKIFYVN	ARHGAP1	176	Q07960
TSVPLLLKNPDYFFK	ST6GALNAC3	131	Q8NDV1
KKAEYQLEPGTFFLF	SLC9A5	96	Q14940
VLKIAPEYAIKFSVF	SLC25A41	156	Q8N5S1
AKLAVQKYEELFPAF	NAPA	221	P54920
FHEVSVYPKKELPFF	ST7	501	Q9NRC1
VYPKKELPFFILFTA	ST7	506	Q9NRC1
LETKVYFAGFPRKVE	PROS1	421	P07225
YFAGFPRKVESELIK	PROS1	426	P07225
HLVFKKIPYEEFFGQ	RASGRF1	1051	Q13972
FKLDEFYIGQIPLKE	SETD1A	81	O15047
VCPDLLNKYFKEVTF	URB1	366	O60287
LNKYFKEVTFSFIPR	URB1	371	O60287
VKDFQPYFKGEIFLD	PRXL2A	121	Q9BRX8
DGFLLPKYFKEALQL	TRPT1	206	Q86TN4
VFVGVKYVNKFASLF	SLC12A4	266	Q9UP95
AYPKLNFVEDSKVVL	SMCR8	111	Q8TEV9
NLSKPFLDIVLYIFK	ABCD3	206	P28288
KLGIPEYFNFAKDVL	ACSM3	51	Q53FZ2
KPLFEEFGKIYELTV	CELF4	71	Q9BZC1
KFNFPYKIDDILSAP	ARMCX1	191	Q9P291
PILYVLISKKFQARF	CMKLR2	301	P46091
QFFIPYTIKSKGIAV	COL10A1	41	Q03692
VKSIKDYGVFIQFPS	PDCD11	736	Q14690
LVTFAKYILGKFFAL	TIMELESS	766	Q9UNS1
DILNIFKTYIPKDFA	ZNF516	1056	Q92618
YKLITFICEIFPEKI	XPO4	981	Q9C0E2
FKIRFEVPKVLIEFY	VPS13A	881	Q96RL7
LIIIFKFSTKVPTFY	TAS1R1	656	Q7RTX1
KIVIPVFNLFVKDIY	RASGEF1A	376	Q8N9B8
LKYTLFQIFSKIDRP	VWF	1361	P04275
DLPIYVKTVFAKGAA	MPDZ	2011	O75970
LQAAFSQYKKVELFP	SFTPD	241	P35247
PDSLLPNIFFTIKYK	SNX14	71	Q9Y5W7
GYKFFTPILESKFKV	RHBG	321	Q9H310
LYFLELTDLFKPAKV	PLPPR3	36	Q6T4P5
GERKCLTFYLPKFFI	TMEM181	406	Q9P2C4
IKFFAKVLLPLVDQY	RYR3	2856	Q15413
FLKPDDIQYFDKLLV	SF3B1	466	O75533
IVEDPDKFYIFKTIL	SRL	371	Q86TD4
VLYNKFITLFVEKLP	STAMBPL1	76	Q96FJ0
PDVKILIAFISYKDF	SPPL2A	131	Q8TCT8
PFTFFDVQKTKYLQI	TMEM104	221	Q8NE00
KVFDSITYPQLEGFK	WDFY4	356	Q6ZS81
KIQIYITDPDFKGFI	TTC3	661	P53804
FSLPKFYLLFGISKV	NF1	2156	P21359
ALFDLEKVSFYFKPS	PREX2	1341	Q70Z35
GFFVRYFPSEDQKKL	SLC9B1	301	Q4ZJI4
SNDPVLKFFKAYGVL	TTC21A	36	Q8NDW8
TFKKTLDDGFFPFII	YLPM1	1916	P49750
ASVFDAYVLPKLYVK	RPS26	56	P62854
SYFPKILTFFVGLAI	SLC39A8	156	Q9C0K1
FKIPFFQKIFKEEYR	TMEM117	281	Q9H0C3
TERIYFQVFLPKGSK	ZFAND1	161	Q8TCF1
FEFFIEDFKTYKPLL	TSNAXIP1	81	Q2TAA8
PGLEQYAIKKFAEAF	CCT8	431	P50990
ILEDKVKNFYTRLPF	TG	1956	P01266
GPKVIFRFALALFKY	TBC1D2B	856	Q9UPU7
YIFKDSFQFDLKPVG	HIVEP1	786	P15822
RFASFPDYLVIQIKK	USP5	561	P45974
PDYLVIQIKKFTFGL	USP5	566	P45974
SFPEYLVVQIKKFTF	USP13	576	Q92995
FYKELGKLLDTFFQI	UGT2A2	116	P0DTE5
PKDIFRLFITIYKDA	ZFYVE16	1111	Q7Z3T8
FFLKVTALTQKPDVY	SIGLEC16	136	A6NMB1
QYISKPLLIDGFKFD	TTLL13	231	A6NNM8
VKKVYLQVLSFFFIG	SLC16A10	356	Q8TF71
AKYDLPATINFIIEK	LIPK	146	Q5VXJ0
YEKNKTFFLEIGEPR	SLC8A1	616	P32418
IKISPALEDFVYKIF	NALCN	486	Q8IZF0
ENDYKFGLTKVFFRP	MYO6	746	Q9UM54
KYGAFEKIPEFIAFR	NAA25	586	Q14CX7