Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dihydropyrimidinase activity	DPYSL2 DPYSL3 DPYSL4	6.54e-07	6	65	3	GO:0004157
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	DPYSL2 DPYSL3 DPYSL4	1.79e-05	16	65	3	GO:0016812
GeneOntologyMolecularFunction	cholesterol-protein transferase activity	DHH SHH	3.12e-05	3	65	2	GO:0140853
GeneOntologyMolecularFunction	patched binding	DHH SHH	2.88e-04	8	65	2	GO:0005113
GeneOntologyMolecularFunction	zinc ion binding	TRIM66 APOBEC3D POLR3B DHH PRICKLE3 TRIM62 RECQL4 SHH AIRE EP300	5.73e-04	891	65	10	GO:0008270
GeneOntologyBiologicalProcess	pyrimidine nucleobase catabolic process	DPYSL2 DPYSL3 DPYSL4	1.50e-06	8	63	3	GO:0006208
GeneOntologyBiologicalProcess	nucleobase catabolic process	DPYSL2 DPYSL3 DPYSL4	7.60e-06	13	63	3	GO:0046113
GeneOntologyBiologicalProcess	pyrimidine-containing compound catabolic process	DPYSL2 DPYSL3 APOBEC3D DPYSL4	1.17e-05	46	63	4	GO:0072529
GeneOntologyBiologicalProcess	intein-mediated protein splicing	DHH SHH	2.75e-05	3	63	2	GO:0016539
GeneOntologyBiologicalProcess	protein splicing	DHH SHH	2.75e-05	3	63	2	GO:0030908
GeneOntologyBiologicalProcess	pyrimidine nucleobase metabolic process	DPYSL2 DPYSL3 DPYSL4	4.01e-05	22	63	3	GO:0006206
GeneOntologyBiologicalProcess	response to cobalamin	EGFR CD40	5.49e-05	4	63	2	GO:0033590
GeneOntologyBiologicalProcess	regulation of response to biotic stimulus	APOBEC3D POLR3B NLRX1 TRIM62 TSPAN6 TLR7 ZDHHC4 NLRP4 EP300	1.38e-04	643	63	9	GO:0002831
GeneOntologyBiologicalProcess	regulation of innate immune response	POLR3B NLRX1 TRIM62 TSPAN6 TLR7 ZDHHC4 NLRP4 EP300	1.75e-04	519	63	8	GO:0045088
GeneOntologyBiologicalProcess	pyrimidine-containing compound metabolic process	DPYSL2 DPYSL3 APOBEC3D DPYSL4	1.81e-04	92	63	4	GO:0072527
HumanPheno	Hypotelorism	KMT2D WDR4 RAB3GAP2 RECQL4 RLIM SHH	1.90e-05	146	21	6	HP:0000601
Domain	Hydantoinase/dihydroPyrase	DPYSL2 DPYSL3 DPYSL4	7.99e-07	6	65	3	IPR011778
Domain	-	DPYSL2 DPYSL3 DPYSL4	2.23e-06	8	65	3	2.30.40.10
Domain	Amidohydro_1	DPYSL2 DPYSL3 DPYSL4	4.74e-06	10	65	3	PF01979
Domain	Metal-dep_hydrolase_composite	DPYSL2 DPYSL3 DPYSL4	4.74e-06	10	65	3	IPR011059
Domain	Amidohydro-rel	DPYSL2 DPYSL3 DPYSL4	6.51e-06	11	65	3	IPR006680
Domain	Hedgehog_sig/DD-Pept_Zn-bd_dom	DHH SHH	3.57e-05	3	65	2	IPR009045
Domain	Hedgehog_signalling_dom	DHH SHH	3.57e-05	3	65	2	IPR000320
Domain	HintN	DHH SHH	3.57e-05	3	65	2	SM00306
Domain	HintC	DHH SHH	3.57e-05	3	65	2	SM00305
Domain	Hedgehog	DHH SHH	3.57e-05	3	65	2	IPR001657
Domain	Hint_dom	DHH SHH	3.57e-05	3	65	2	IPR001767
Domain	-	DHH SHH	3.57e-05	3	65	2	3.30.1380.10
Domain	Hint_dom_N	DHH SHH	3.57e-05	3	65	2	IPR003587
Domain	Hint_dom_C	DHH SHH	3.57e-05	3	65	2	IPR003586
Domain	HH_signal	DHH SHH	3.57e-05	3	65	2	PF01085
Domain	Hint	DHH SHH	3.57e-05	3	65	2	PF01079
Domain	-	DHH SHH	7.12e-05	4	65	2	2.170.16.10
Domain	Hedgehog/Intein_dom	DHH SHH	7.12e-05	4	65	2	IPR028992
Domain	Metal_Hydrolase	DPYSL2 DPYSL3 DPYSL4	7.73e-05	24	65	3	IPR032466
Domain	Hirudin/antistatin	CRIM1 MUC5AC	2.48e-04	7	65	2	IPR011061
Domain	Ldl_recept_a	MALRD1 LDLRAD1 LRP1B	5.14e-04	45	65	3	PF00057
Domain	-	MALRD1 LDLRAD1 LRP1B	5.49e-04	46	65	3	4.10.400.10
Domain	LDLRA_1	MALRD1 LDLRAD1 LRP1B	6.22e-04	48	65	3	PS01209
Domain	LDLRA_2	MALRD1 LDLRAD1 LRP1B	6.61e-04	49	65	3	PS50068
Domain	LDrepeatLR_classA_rpt	MALRD1 LDLRAD1 LRP1B	6.61e-04	49	65	3	IPR002172
Domain	LDLa	MALRD1 LDLRAD1 LRP1B	6.61e-04	49	65	3	SM00192
Domain	-	RMND5B TRIM66 KMT2D TRIM62 RLIM MTMR3 AIRE	9.27e-04	449	65	7	3.30.40.10
Domain	EGF	HGFAC MALRD1 SLIT3 LRP1B	9.73e-04	126	65	4	PF00008
Domain	Znf_RING/FYVE/PHD	RMND5B TRIM66 KMT2D TRIM62 RLIM MTMR3 AIRE	1.05e-03	459	65	7	IPR013083
Domain	Znf_FYVE_PHD	TRIM66 KMT2D MTMR3 AIRE	1.72e-03	147	65	4	IPR011011
Domain	CTCK_1	SLIT3 MUC5AC	1.76e-03	18	65	2	PS01185
Domain	VWC_out	CRIM1 MUC5AC	1.96e-03	19	65	2	SM00215
Domain	Growth_fac_rcpt_	CRIM1 EGFR SLIT3 LRP1B	2.13e-03	156	65	4	IPR009030
Domain	PHD	TRIM66 KMT2D AIRE	2.27e-03	75	65	3	PF00628
Domain	GST_N	GSTT2 GSTT2B	2.63e-03	22	65	2	PF02798
Domain	GST_NTER	GSTT2 GSTT2B	2.63e-03	22	65	2	PS50404
Domain	CT	SLIT3 MUC5AC	2.63e-03	22	65	2	SM00041
Domain	Znf_PHD-finger	TRIM66 KMT2D AIRE	2.63e-03	79	65	3	IPR019787
Domain	NACHT	NLRX1 NLRP4	2.88e-03	23	65	2	PS50837
Domain	NACHT_NTPase	NLRX1 NLRP4	2.88e-03	23	65	2	IPR007111
Domain	SEC14	MCF2L SEC14L5	3.40e-03	25	65	2	SM00516
Domain	Cys_knot_C	SLIT3 MUC5AC	3.40e-03	25	65	2	IPR006207
Domain	CTCK_2	SLIT3 MUC5AC	3.40e-03	25	65	2	PS01225
Domain	GST_C	GSTT2 GSTT2B	3.67e-03	26	65	2	IPR004046
Domain	GST_C	GSTT2 GSTT2B	3.67e-03	26	65	2	PF00043
Domain	PHD	TRIM66 KMT2D AIRE	3.69e-03	89	65	3	SM00249
Domain	Znf_PHD	TRIM66 KMT2D AIRE	3.93e-03	91	65	3	IPR001965
Domain	CRAL_TRIO	MCF2L SEC14L5	3.96e-03	27	65	2	PS50191
Domain	Glutathione_S-Trfase_N	GSTT2 GSTT2B	3.96e-03	27	65	2	IPR004045
Domain	CRAL-TRIO_dom	MCF2L SEC14L5	4.25e-03	28	65	2	IPR001251
Domain	VWC	CRIM1 MUC5AC	4.25e-03	28	65	2	PF00093
Domain	ZF_PHD_2	TRIM66 KMT2D AIRE	4.43e-03	95	65	3	PS50016
Domain	ZF_PHD_1	TRIM66 KMT2D AIRE	4.57e-03	96	65	3	PS01359
Domain	LRRCT	SLIT3 TLR7	5.53e-03	32	65	2	PF01463
Domain	L_dom-like	EGFR NLRX1 SLIT3 TLR7 NLRP4	5.66e-03	328	65	5	IPR032675
Domain	GST_CTER	GSTT2 GSTT2B	6.23e-03	34	65	2	PS50405
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	DPYSL2 DPYSL3 DPYSL4	1.64e-05	15	48	3	MM15031
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	DPYSL2 DPYSL3 DPYSL4	2.01e-05	16	48	3	M8245
Pathway	KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_HH_LIGAND_SECRETION	DHH SHH	1.69e-04	6	48	2	M47892
Pathway	REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL	DHH SHH	2.36e-04	7	48	2	MM15187
Pathway	REACTOME_LIGAND_RECEPTOR_INTERACTIONS	DHH SHH	2.36e-04	7	48	2	MM15224
Pathway	REACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL	DHH SHH	3.14e-04	8	48	2	M27444
Pathway	REACTOME_LIGAND_RECEPTOR_INTERACTIONS	DHH SHH	3.14e-04	8	48	2	M27496
Pathway	KEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR	DHH SHH	4.03e-04	9	48	2	M47893
Pubmed	Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.	DPYSL2 DPYSL3 DPYSL4	6.23e-09	3	65	3	11771764
Pubmed	Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.	DPYSL2 DPYSL3 DPYSL4	2.49e-08	4	65	3	10664068
Pubmed	The Ulip family phosphoproteins--common and specific properties.	DPYSL2 DPYSL3 DPYSL4	2.49e-08	4	65	3	9652388
Pubmed	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.	DPYSL2 DPYSL3 DPYSL4	6.21e-08	5	65	3	8973361
Pubmed	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.	DPYSL2 DPYSL3 DPYSL4	1.24e-07	6	65	3	10956643
Pubmed	CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.	DPYSL2 DPYSL3 DPYSL4	3.47e-07	8	65	3	12134159
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TRIM66 MTMR3 KDM6B MCF2L PLXNB2	1.55e-06	104	65	5	9205841
Pubmed	GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.	DHH SHH MUC5AC	3.43e-06	16	65	3	26932670
Pubmed	Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.	EGFR MUC5AC	3.44e-06	2	65	2	20525715
Pubmed	Increased expression of mucin 5AC mRNA and decreased expression of epidermal growth-factor receptor mRNA in gallstone patients.	EGFR MUC5AC	3.44e-06	2	65	2	18285671
Pubmed	FHL2 interacts with EGFR to promote glioblastoma growth.	EGFR FHL2	3.44e-06	2	65	2	29321665
Pubmed	Mouse pups lacking collapsin response mediator protein 4 manifest impaired olfactory function and hyperactivity in the olfactory bulb.	DPYSL3 DPYSL4	3.44e-06	2	65	2	26118640
Pubmed	TLR7 Negatively Regulates B10 Cells Predominantly in an IFNγ Signaling Dependent Manner.	IFNGR1 TLR7	3.44e-06	2	65	2	32849556
Pubmed	p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization.	RECQL4 EP300	3.44e-06	2	65	2	19299466
Pubmed	Mammalian class theta GST and differential susceptibility to carcinogens: a review.	GSTT2 GSTT2B	3.44e-06	2	65	2	11018744
Pubmed	Characterization of a cDNA and gene encoding the mouse theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1.	GSTT2 GSTT2B	3.44e-06	2	65	2	8617493
Pubmed	Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice.	DHH SHH	3.44e-06	2	65	2	24135022
Pubmed	Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.	DPYSL2 DPYSL3	3.44e-06	2	65	2	22826151
Pubmed	Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22.	GSTT2 GSTT2B	3.44e-06	2	65	2	7789971
Pubmed	Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.	GSTT2 GSTT2B	3.44e-06	2	65	2	9854036
Pubmed	Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.	GSTT2 GSTT2B	3.44e-06	2	65	2	12038961
Pubmed	[Roles of epidermal growth factor receptor signaling pathway on cultured human nasal epithelial cells RPMI-2650].	EGFR MUC5AC	3.44e-06	2	65	2	19558858
Pubmed	Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.	GSTT2 GSTT2B	3.44e-06	2	65	2	19424424
Pubmed	EGF-Receptor-Dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis.	EGFR TLR7	3.44e-06	2	65	2	37268107
Pubmed	MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder.	EGFR MUC5AC	3.44e-06	2	65	2	17148666
Pubmed	Characterization of a human class-Theta glutathione S-transferase with activity towards 1-menaphthyl sulphate.	GSTT2 GSTT2B	3.44e-06	2	65	2	1417752
Pubmed	[Hedgehog signaling pathway and its impact on development of cancer therapy].	DHH SHH	1.03e-05	3	65	2	18788453
Pubmed	Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.	DHH SHH	1.03e-05	3	65	2	19561611
Pubmed	The hedgehog signaling pathway in the mouse ovary.	DHH SHH	1.03e-05	3	65	2	17392501
Pubmed	MUC5AC expression through bidirectional communication of Notch and epidermal growth factor receptor pathways.	EGFR MUC5AC	1.03e-05	3	65	2	21622856
Pubmed	The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.	KMT2D EP300	1.03e-05	3	65	2	37410700
Pubmed	Frontline Science: CD40 signaling restricts RNA virus replication in Mϕs, leading to rapid innate immune control of acute virus infection.	IFNGR1 CD40	1.03e-05	3	65	2	32441445
Pubmed	Experimental validation of 5 in-silico predicted glioma biomarkers.	SLIT3 PLXNB2	1.03e-05	3	65	2	24158112
Pubmed	A role for IFNgamma in differential superantigen stimulation of conventional versus plasmacytoid DCs.	IFNGR1 CD40	1.03e-05	3	65	2	17045255
Pubmed	Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target.	DHH SHH	1.03e-05	3	65	2	19074837
Pubmed	Evolution of the hedgehog gene family.	DHH SHH	1.03e-05	3	65	2	8849902
Pubmed	EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.	EGFR EP300	1.03e-05	3	65	2	25996283
Pubmed	The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.	DHH SHH	1.03e-05	3	65	2	18063705
Pubmed	Monocyte-derived CD40 expression is regulated by interferon-γ/interferon-γ receptor-1 pathway when acting as a bridge during their interaction with T cells and allogeneic endothelial cells.	IFNGR1 CD40	1.03e-05	3	65	2	22564607
Pubmed	The world according to hedgehog.	DHH SHH	1.03e-05	3	65	2	9009843
Pubmed	Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.	EGFR MUC5AC	1.03e-05	3	65	2	26100173
Pubmed	The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human.	GSTT2 GSTT2B	1.03e-05	3	65	2	8761485
Pubmed	Hedgehog signal transduction: from flies to vertebrates.	DHH SHH	1.03e-05	3	65	2	10579908
Pubmed	Proteomic analysis of neonatal mouse brain: evidence for hypoxia- and ischemia-induced dephosphorylation of collapsin response mediator proteins.	DPYSL2 DPYSL3	1.03e-05	3	65	2	18471005
Pubmed	MicroRNA-145 down-regulates mucin 5AC to alleviate airway remodeling and targets EGFR to inhibit cytokine expression.	EGFR MUC5AC	1.03e-05	3	65	2	28564633
Pubmed	[Expression of sonic hedgehog, EGFR and PCNA proteins in pancreatic cancer and their correlations to cell proliferation].	EGFR SHH	1.03e-05	3	65	2	17927850
Pubmed	Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.	GSTT2 GSTT2B	1.03e-05	3	65	2	30783009
Pubmed	Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.	EGFR MUC5AC	1.03e-05	3	65	2	18978302
Pubmed	A new role for Hedgehogs in juxtacrine signaling.	DHH SHH	1.03e-05	3	65	2	24342078
Pubmed	A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.	KMT2D EP300	1.03e-05	3	65	2	28732206
Pubmed	Comparative biological responses to human Sonic, Indian, and Desert hedgehog.	DHH SHH	1.03e-05	3	65	2	11472839
Pubmed	Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability.	DHH SHH	2.06e-05	4	65	2	33063110
Pubmed	Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina.	DHH SHH	2.06e-05	4	65	2	9053312
Pubmed	LPS increases MUC5AC by TACE/TGF-α/EGFR pathway in human intrahepatic biliary epithelial cell.	EGFR MUC5AC	2.06e-05	4	65	2	24027752
Pubmed	Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.	HCAR3 EGFR	2.06e-05	4	65	2	25375133
Pubmed	Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.	DHH SHH	2.06e-05	4	65	2	7916661
Pubmed	CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation.	DPYSL2 DPYSL3	2.06e-05	4	65	2	24227739
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2D EP300	2.06e-05	4	65	2	28398509
Pubmed	Identification, characterization, and crystal structure of the Omega class glutathione transferases.	GSTT2 GSTT2B	2.06e-05	4	65	2	10783391
Pubmed	Human Neutrophil Elastase Mediates MUC5AC Hypersecretion via the Tumour Necrosis Factor-α Converting Enzyme-Epidermal Growth Factor Receptor Signalling Pathway in vivo.	EGFR MUC5AC	2.06e-05	4	65	2	34130299
Pubmed	Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.	EGFR EP300	2.06e-05	4	65	2	28759294
Pubmed	Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.	DPYSL3 DPYSL4	2.06e-05	4	65	2	25358863
Pubmed	Enterovirus 71 modulates a COX-2/PGE2/cAMP-dependent viral replication in human neuroblastoma cells: role of the c-Src/EGFR/p42/p44 MAPK/CREB signaling pathway.	EGFR EP300	2.06e-05	4	65	2	21268077
Pubmed	PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.	WDR4 EGFR	2.06e-05	4	65	2	37821451
Pubmed	P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain.	AIRE EP300	2.06e-05	4	65	2	12929931
Pubmed	Progranulin aggravates lethal Candida albicans sepsis by regulating inflammatory response and antifungal immunity.	IFNGR1 TLR7	3.43e-05	5	65	2	36121866
Pubmed	Developmental pathways in breast cancer and breast tumor-initiating cells: therapeutic implications.	DHH SHH	3.43e-05	5	65	2	22123293
Pubmed	Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex.	GSTT2 GSTT2B	3.43e-05	5	65	2	9729470
Pubmed	Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells.	DHH SHH	3.43e-05	5	65	2	19559697
Pubmed	Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.	DPYSL2 DPYSL3	3.43e-05	5	65	2	16611631
Pubmed	CRIM1, a novel gene encoding a cysteine-rich repeat protein, is developmentally regulated and implicated in vertebrate CNS development and organogenesis.	CRIM1 SHH	3.43e-05	5	65	2	10642437
Pubmed	Rapid elimination of Toxoplasma gondii by gamma interferon-primed mouse macrophages is independent of CD40 signaling.	IFNGR1 CD40	3.43e-05	5	65	2	17682046
Pubmed	Akt1 interacts with epidermal growth factor receptors and hedgehog signaling to increase stem/transit amplifying cells in the embryonic mouse cortex.	EGFR SHH	3.43e-05	5	65	2	21312341
Pubmed	Hedgehog and patched gene expression in adult ocular tissues.	DHH SHH	3.43e-05	5	65	2	9237688
Pubmed	The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-α-EGFR pathway.	EGFR MUC5AC	3.43e-05	5	65	2	24901072
Pubmed	Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.	IFNGR1 TLR7	3.43e-05	5	65	2	15654326
Pubmed	Coordination between TLR9 signaling in macrophages and CD3 signaling in T cells induces robust expression of IL-30.	IFNGR1 CD40	3.43e-05	5	65	2	22407920
Pubmed	Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.	CD40 AIRE	3.43e-05	5	65	2	18350550
Pubmed	Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin.	FHL2 EP300	3.43e-05	5	65	2	15572674
Pubmed	Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.	DHH SHH	3.43e-05	5	65	2	10050855
Pubmed	All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.	DHH SHH	3.43e-05	5	65	2	20519495
Pubmed	Plasmacytoid dendritic cells orchestrate TLR7-mediated innate and adaptive immunity for the initiation of autoimmune inflammation.	CD40 TLR7	3.43e-05	5	65	2	27075414
Pubmed	Aire-expressing ILC3-like cells in the lymph node display potent APC features.	CD40 AIRE	3.43e-05	5	65	2	30918005
Pubmed	Products, genetic linkage and limb patterning activity of a murine hedgehog gene.	DHH SHH	3.43e-05	5	65	2	7720571
Pubmed	Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance.	CD40 AIRE	3.43e-05	5	65	2	27705788
Pubmed	EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex.	EGFR NLRX1	3.43e-05	5	65	2	26876213
Pubmed	Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion.	IFNGR1 TLR7	3.43e-05	5	65	2	20956347
Pubmed	Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.	CD40 TLR7	5.13e-05	6	65	2	17114424
Pubmed	Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.	FHL2 EP300	5.13e-05	6	65	2	22219185
Pubmed	Type I Interferons Triggered through the Toll-Like Receptor 3-TRIF Pathway Control Coxsackievirus A16 Infection in Young Mice.	IFNGR1 TLR7	5.13e-05	6	65	2	26292317
Pubmed	CCL20/CCR6 feedback exaggerates epidermal growth factor receptor-dependent MUC5AC mucin production in human airway epithelial (NCI-H292) cells.	EGFR MUC5AC	5.13e-05	6	65	2	21300824
Pubmed	Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses.	CD40 TLR7	5.13e-05	6	65	2	19710454
Pubmed	Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.	EGFR SHH	5.13e-05	6	65	2	14681189
Pubmed	Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination.	DPYSL2 KDM6B	5.13e-05	6	65	2	19926752
Pubmed	TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses.	CD40 TLR7	5.13e-05	6	65	2	17277123
Pubmed	Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor.	DHH SHH	5.13e-05	6	65	2	20978073
Pubmed	Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.	DHH SHH	5.13e-05	6	65	2	7589793
Pubmed	STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.	IFNGR1 TLR7	5.13e-05	6	65	2	27792766
Pubmed	LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.	KMT2D EP300	7.18e-05	7	65	2	37166352
Pubmed	Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells.	DHH SHH	7.18e-05	7	65	2	32679029
Interaction	ASH2L interactions	KMT2D EGFR RAB3GAP2 RECQL4 KDM6B FHL2 ZRANB1 EP300	1.88e-06	265	64	8	int:ASH2L
Interaction	NMD3 interactions	LDLRAD1 EGFR RECQL4 ZRANB1 GSTT2B EP300	2.22e-06	120	64	6	int:NMD3
Interaction	RPIA interactions	IVNS1ABP DHH EGFR KDM6B ZRANB1	2.84e-06	70	64	5	int:RPIA
Interaction	DPYS interactions	DPYSL2 DPYSL3 DPYSL4	6.58e-06	12	64	3	int:DPYS
Interaction	POLR2A interactions	IVNS1ABP DPYSL3 KMT2D POLR3B EGFR ASB6 RECQL4 AIRE ZRANB1 EP300	6.79e-06	536	64	10	int:POLR2A
Interaction	DBR1 interactions	EGFR RECQL4 ZRANB1 EP300	7.76e-06	40	64	4	int:DBR1
Interaction	ELP3 interactions	KMT2D POLR3B EGFR RECQL4 ZRANB1 EP300	7.78e-06	149	64	6	int:ELP3
Interaction	MCMBP interactions	EGFR RHOBTB2 RECQL4 KDM6B ZRANB1 EP300	1.05e-05	157	64	6	int:MCMBP
Interaction	ROBO4 interactions	EGFR SLIT3 EP300	1.08e-05	14	64	3	int:ROBO4
Interaction	TRMT61A interactions	DPYSL2 EGFR RLIM FHL2 ZRANB1	1.10e-05	92	64	5	int:TRMT61A
Interaction	DNPEP interactions	TMLHE RECQL4 KDM6B ZRANB1 EP300	1.10e-05	92	64	5	int:DNPEP
Interaction	RPAP2 interactions	POLR3B EGFR ASB6 RECQL4 ZRANB1 EP300	1.13e-05	159	64	6	int:RPAP2
Interaction	DHRS2 interactions	EGFR TMLHE PHTF2 TRMT13 ZRANB1	1.15e-05	93	64	5	int:DHRS2
Interaction	KRT17 interactions	DPYSL2 DPYSL3 EGFR RLIM KDM6B ZRANB1 ARAP2	1.49e-05	252	64	7	int:KRT17
Interaction	DNAJC10 interactions	TRIM66 EGFR RECQL4 RLIM MTMR3 LRP1B ZRANB1	1.82e-05	260	64	7	int:DNAJC10
Interaction	MCM6 interactions	IVNS1ABP EGFR RHOBTB2 RECQL4 AIRE ZRANB1 EP300	3.43e-05	287	64	7	int:MCM6
Interaction	COPS4 interactions	EGFR ASB6 RHOBTB2 RECQL4 ZRANB1 EP300	5.12e-05	208	64	6	int:COPS4
Interaction	PNO1 interactions	EGFR RECQL4 MTMR3 ZRANB1 EP300	5.60e-05	129	64	5	int:PNO1
Interaction	AHR interactions	IVNS1ABP TRIM66 FHL2 ZRANB1 EP300	6.25e-05	132	64	5	int:AHR
Interaction	DNAAF10 interactions	POLR3B WDR4 EGFR RECQL4 ZRANB1	6.48e-05	133	64	5	int:DNAAF10
Interaction	GPS1 interactions	EGFR ASB6 RHOBTB2 RECQL4 ZRANB1 EP300	6.65e-05	218	64	6	int:GPS1
Interaction	FBXO3 interactions	RECQL4 AIRE ZRANB1 EP300	8.09e-05	72	64	4	int:FBXO3
Interaction	DUT interactions	POLR3B EGFR RHOBTB2 RECQL4 ZRANB1	8.26e-05	140	64	5	int:DUT
Interaction	XPO5 interactions	WDR4 EGFR CD40 KDM6B ZRANB1 EP300	8.31e-05	227	64	6	int:XPO5
Interaction	APBB3 interactions	HGFAC EGFR RHOBTB2	8.46e-05	27	64	3	int:APBB3
Interaction	SUDS3 interactions	EGFR RHOBTB2 FHL2 ZRANB1 EP300	8.54e-05	141	64	5	int:SUDS3
Interaction	AAMP interactions	EGFR RECQL4 ZRANB1 EP300	9.49e-05	75	64	4	int:AAMP
Interaction	RPRD1B interactions	POLR3B EGFR ASB6 RECQL4 ZRANB1 EP300	9.59e-05	233	64	6	int:RPRD1B
Interaction	SP5 interactions	EGFR ZRANB1	9.87e-05	5	64	2	int:SP5
Interaction	RAE1 interactions	HGFAC POLR3B EGFR GYG2 KDM6B ZRANB1	1.03e-04	236	64	6	int:RAE1
Interaction	PANK4 interactions	TRIM66 EGFR ZRANB1 EP300	1.05e-04	77	64	4	int:PANK4
Interaction	NUBP1 interactions	DPYSL2 POLR3B EGFR ZRANB1	1.16e-04	79	64	4	int:NUBP1
Interaction	CADPS2 interactions	WDR4 ASB6 ZRANB1	1.17e-04	30	64	3	int:CADPS2
Interaction	NCBP1 interactions	IVNS1ABP APOBEC3D EGFR RHOBTB2 RECQL4 ZRANB1 EP300	1.26e-04	353	64	7	int:NCBP1
Interaction	POLD2 interactions	EGFR RECQL4 ZRANB1 EP300	1.28e-04	81	64	4	int:POLD2
Interaction	TBC1D3K interactions	EGFR ZRANB1	1.48e-04	6	64	2	int:TBC1D3K
Interaction	MRPL17 interactions	APOBEC3D POLR3B EGFR RECQL4 ZRANB1	1.55e-04	160	64	5	int:MRPL17
Interaction	PELO interactions	TRIM66 EGFR RECQL4 ZRANB1 EP300	1.59e-04	161	64	5	int:PELO
Interaction	GANAB interactions	IVNS1ABP EGFR RHOBTB2 RECQL4 KDM6B ZRANB1 EP300	1.62e-04	368	64	7	int:GANAB
Interaction	COPS2 interactions	EGFR ASB6 RHOBTB2 RECQL4 ZRANB1 EP300	1.67e-04	258	64	6	int:COPS2
Interaction	EXOSC5 interactions	EGFR TRIM62 RECQL4 MTMR3 ZRANB1	1.74e-04	164	64	5	int:EXOSC5
Interaction	ARPC4 interactions	EGFR RHOBTB2 RECQL4 RLIM ZRANB1	1.79e-04	165	64	5	int:ARPC4
Interaction	ZNF626 interactions	EGFR FHL2	2.06e-04	7	64	2	int:ZNF626
Interaction	TBC1D3C interactions	EGFR ZRANB1	2.06e-04	7	64	2	int:TBC1D3C
Interaction	BRF1 interactions	POLR3B LDLRAD1 EGFR RLIM	2.10e-04	92	64	4	int:BRF1
Interaction	PCID2 interactions	TRIM66 EGFR KDM6B ZRANB1	2.10e-04	92	64	4	int:PCID2
Interaction	TWF1 interactions	EGFR PRICKLE3 RHOBTB2 RLIM MUC5AC	2.17e-04	172	64	5	int:TWF1
Interaction	POLR2L interactions	POLR3B EGFR ASB6 ZRANB1 EP300	2.17e-04	172	64	5	int:POLR2L
Interaction	GMPS interactions	EGFR RECQL4 KDM6B ZRANB1 EP300	2.17e-04	172	64	5	int:GMPS
Interaction	MSH6 interactions	IVNS1ABP RAB3GAP2 RECQL4 AIRE ZRANB1 EP300	2.18e-04	271	64	6	int:MSH6
Interaction	LANCL2 interactions	EGFR RECQL4 AIRE ZRANB1	2.18e-04	93	64	4	int:LANCL2
Interaction	WRAP53 interactions	EGFR RECQL4 ZRANB1 EP300	2.28e-04	94	64	4	int:WRAP53
Interaction	NOSIP interactions	EGFR RECQL4 ZRANB1 EP300	2.37e-04	95	64	4	int:NOSIP
Interaction	RNMT interactions	DPYSL2 EGFR RECQL4 ZRANB1	2.37e-04	95	64	4	int:RNMT
Interaction	FBLL1 interactions	TRIM66 ZRANB1 EP300	2.38e-04	38	64	3	int:FBLL1
Interaction	TRMT112 interactions	EGFR RECQL4 RLIM ZRANB1	2.47e-04	96	64	4	int:TRMT112
Interaction	RHOBTB3 interactions	TRIM66 LDLRAD1 RHOBTB2 ZRANB1	2.47e-04	96	64	4	int:RHOBTB3
Interaction	RFC3 interactions	LDLRAD1 EGFR RECQL4 ZRANB1 EP300	2.48e-04	177	64	5	int:RFC3
Interaction	KCTD5 interactions	EGFR RECQL4 ZRANB1 EP300	2.57e-04	97	64	4	int:KCTD5
Interaction	WDR26 interactions	RMND5B EGFR PRICKLE3 RECQL4 ZRANB1	2.61e-04	179	64	5	int:WDR26
Interaction	GRN interactions	DPYSL3 LDLRAD1 EGFR RLIM ZRANB1 EP300	2.65e-04	281	64	6	int:GRN
Interaction	CCN2 interactions	EGFR ZRANB1 EP300	2.78e-04	40	64	3	int:CCN2
Interaction	NAE1 interactions	DPYSL2 EGFR RECQL4 ZRANB1	2.78e-04	99	64	4	int:NAE1
Interaction	NSMCE3 interactions	EGFR RECQL4 ZRANB1	2.99e-04	41	64	3	int:NSMCE3
Interaction	PROX1 interactions	TRIM66 ZRANB1 EP300	2.99e-04	41	64	3	int:PROX1
Interaction	VPS51 interactions	TRIM66 DHH EGFR ZRANB1 EP300	3.04e-04	185	64	5	int:VPS51
Interaction	SRSF2 interactions	EGFR RHOBTB2 AIRE SFI1 ZRANB1 EP300	3.14e-04	290	64	6	int:SRSF2
Interaction	GNE interactions	SSC4D RAB3GAP2 ZRANB1 EP300	3.35e-04	104	64	4	int:GNE
Interaction	RCC1L interactions	DHH EGFR RECQL4 ZRANB1	3.35e-04	104	64	4	int:RCC1L
Interaction	DYRK1A interactions	TRIM66 DPYSL2 DPYSL3 KMT2D CRIM1 FHL2 LRP1B EP300	3.46e-04	552	64	8	int:DYRK1A
Interaction	AKAP8 interactions	TRIM66 RECQL4 KDM6B ZRANB1 EP300	3.69e-04	193	64	5	int:AKAP8
Interaction	AP2A1 interactions	DPYSL2 EGFR RECQL4 RLIM ZRANB1 EP300	3.69e-04	299	64	6	int:AP2A1
Interaction	USP9X interactions	EGFR RHOBTB2 RECQL4 SFI1 KDM6B ZRANB1 EP300	3.73e-04	422	64	7	int:USP9X
Interaction	GPN3 interactions	POLR3B ASB6 RECQL4 ZRANB1	3.74e-04	107	64	4	int:GPN3
Interaction	CIAO2B interactions	TRIM66 EGFR RECQL4 ZRANB1	3.74e-04	107	64	4	int:CIAO2B
Interaction	ZFR interactions	APOBEC3D EGFR RECQL4 FHL2 ZRANB1 EP300	3.83e-04	301	64	6	int:ZFR
Interaction	GTF3C4 interactions	IVNS1ABP EGFR RECQL4 MTMR3 ZRANB1	3.87e-04	195	64	5	int:GTF3C4
Interaction	PDCD2 interactions	RECQL4 ZRANB1 EP300	3.94e-04	45	64	3	int:PDCD2
Interaction	DDX17 interactions	IVNS1ABP WDR4 EGFR RECQL4 AIRE ZRANB1 EP300	3.95e-04	426	64	7	int:DDX17
Interaction	DHX36 interactions	IVNS1ABP APOBEC3D EGFR RECQL4 ZRANB1 EP300	3.96e-04	303	64	6	int:DHX36
Interaction	MLST8 interactions	EGFR CD40 MTMR3 EP300	4.01e-04	109	64	4	int:MLST8
Interaction	CUL5 interactions	DPYSL2 WDR4 EGFR ASB6 RHOBTB2 RECQL4 ZRANB1 EP300	4.14e-04	567	64	8	int:CUL5
Interaction	POLR3C interactions	POLR3B EGFR ZRANB1 EP300	4.15e-04	110	64	4	int:POLR3C
Interaction	TNPO1 interactions	EGFR RECQL4 CD40 KDM6B ZRANB1 EP300	4.18e-04	306	64	6	int:TNPO1
Interaction	ZNF706 interactions	DPYSL2 ZRANB1	4.39e-04	10	64	2	int:ZNF706
Interaction	IGKV2D-24 interactions	RECQL4 ZRANB1	4.39e-04	10	64	2	int:IGKV2D-24
Interaction	HHIP interactions	DHH SHH	4.39e-04	10	64	2	int:HHIP
Interaction	LTN1 interactions	IVNS1ABP TRIM66 EGFR CD40 ZRANB1	4.44e-04	201	64	5	int:LTN1
Interaction	RCC1 interactions	DPYSL2 EGFR RECQL4 ZRANB1 EP300	4.44e-04	201	64	5	int:RCC1
Interaction	TRMT1L interactions	POLR3B EGFR RECQL4 ZRANB1 EP300	4.44e-04	201	64	5	int:TRMT1L
Interaction	LANCL1 interactions	EGFR RECQL4 LRP1B ZRANB1	4.44e-04	112	64	4	int:LANCL1
Interaction	MMS19 interactions	TRIM66 EGFR RHOBTB2 RECQL4 ZRANB1 EP300	4.55e-04	311	64	6	int:MMS19
Interaction	TBR1 interactions	RMND5B KMT2D RECQL4 EP300	4.59e-04	113	64	4	int:TBR1
Interaction	MCAT interactions	EGFR RECQL4 ZRANB1 EP300	4.75e-04	114	64	4	int:MCAT
Interaction	MLXIPL interactions	EGFR ZRANB1 EP300	4.77e-04	48	64	3	int:MLXIPL
Interaction	CSE1L interactions	EGFR RHOBTB2 RECQL4 CD40 ZRANB1 EP300	4.79e-04	314	64	6	int:CSE1L
Interaction	PATE1 interactions	EGFR PLXNB2 LRP1B	5.07e-04	49	64	3	int:PATE1
Interaction	NOB1 interactions	POLR3B RECQL4 ZRANB1 EP300	5.07e-04	116	64	4	int:NOB1
Interaction	MCM3AP interactions	TRIM66 EGFR ZRANB1 EP300	5.24e-04	117	64	4	int:MCM3AP
Interaction	TBC1D3G interactions	EGFR ZRANB1	5.36e-04	11	64	2	int:TBC1D3G
Cytoband	Xp22.3	GYG2 TLR7	4.90e-04	23	65	2	Xp22.3
Cytoband	22q11.23	GSTT2 GSTT2B	2.60e-03	53	65	2	22q11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	KMT2D DHH FIGNL2 DGKA	3.09e-03	423	65	4	chr12q13
Cytoband	22q12.2	MTMR3 SFI1	3.10e-03	58	65	2	22q12.2
GeneFamily	PHD finger proteins	TRIM66 KMT2D AIRE	1.75e-03	90	48	3	88
GeneFamily	NLR family	NLRX1 NLRP4	1.99e-03	25	48	2	666
GeneFamily	Glutathione S-transferases	GSTT2 GSTT2B	1.99e-03	25	48	2	567
Coexpression	GSE17721_LPS_VS_POLYIC_0.5H_BMDC_DN	WDR4 PI16 RHOBTB2 SLIT3 SHH ZNF639	1.01e-05	199	65	6	M3797
ToppCell	facs-Brain_Myeloid-Cortex\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IVNS1ABP HGFAC EGFR TSPAN6 PLXNB2	7.33e-06	184	65	5	17f63dd671f9ff3dd2860d8de41b05c35c095950
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3 FHL2	9.72e-06	195	65	5	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW12-Neuronal-GABAergic_neurons\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TRIM66 HGFAC APOBEC3D POLR3B FBXW12	9.72e-06	195	65	5	efdea22118d5be46c5abfe8e3fbe39503390665d
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Malignant_Peripheral_Nerve_Sheath_Tumors\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	DHH ANKUB1 SHH LRP1B	5.70e-05	143	65	4	d1c8e15a8ae2094de2919e99188f9211b78c5abf
ToppCell	Influenza_Severe-Treg\|Influenza_Severe / Disease group and Cell class	PI16 PRSS38 TRMT13 MCF2L	7.60e-05	154	65	4	77845bcb243aa1b1f1ca00f9ef2ae1b4d1bd3696
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPYSL3 P2RX1 SLIT3 PLXNB2	8.39e-05	158	65	4	1635a85fc73c544028418087f36d28957dd4f458
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DPYSL3 P2RX1 SLIT3 PLXNB2	8.39e-05	158	65	4	80841dadfa53bcde36a3e486408a095f78e772eb
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	KMT2D POLR3B PHTF2 EP300	8.60e-05	159	65	4	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	Bronchial_Biopsy-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	HCAR3 APOBEC3D PI16 TMLHE	9.24e-05	162	65	4	985adca17b0c99563feef7910f3da5df31e636b6
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	MALRD1 TSPAN6 FHL2 ARAP2	1.11e-04	170	65	4	776d4224a682b6c648041827efd69794f88906f0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HGFAC DPYSL3 ASB6 DPYSL4	1.27e-04	176	65	4	8eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells-mDC\|Control_saline / Treatment groups by lineage, cell group, cell type	RLIM CD40 PHTF2 AIRE	1.42e-04	181	65	4	818ac31a718e9b29feb4c4eecbc339e6af45254a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 P2RX1 MCF2L FHL2	1.48e-04	183	65	4	5a936fb07074cec753bf19e3e3e52499605ea22c
ToppCell	IPF-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	DPYSL3 EGFR SLIT3 TMEM151A	1.48e-04	183	65	4	7df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 P2RX1 MCF2L FHL2	1.48e-04	183	65	4	07c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 FHL2 SEC14L5 ARAP2	1.57e-04	186	65	4	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IVNS1ABP IFNGR1 EGFR MCF2L	1.57e-04	186	65	4	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	IVNS1ABP IFNGR1 EGFR MCF2L	1.57e-04	186	65	4	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC DPYSL2 MCF2L FHL2	1.57e-04	186	65	4	32d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI16 PHTF2 TMEM151A FHL2	1.60e-04	187	65	4	fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCell	facs-Skin-Anagen-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 DPYSL2 DPYSL3 PI16	1.60e-04	187	65	4	908df5520142d65fe32a003d26be14965082a1ea
ToppCell	facs-Skin-Anagen-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 DPYSL2 DPYSL3 PI16	1.60e-04	187	65	4	c1dfab0b0d7f519b9f13f4e0365ab41c4b2ae1ec
ToppCell	facs-Skin-Anagen-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 DPYSL2 DPYSL3 PI16	1.60e-04	187	65	4	b486cc5ac678051fea9d4c7db53b26a5a8427e60
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 DPYSL3 PI16 SLIT3	1.60e-04	187	65	4	2c145e9d11424939dd99012a8cedf5d998b966e9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.64e-04	188	65	4	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	droplet-Fat-Scat-21m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 CRIM1 TSPAN6 MCF2L	1.64e-04	188	65	4	8671fdbc4138e6f9559920779c98628ed80f0da3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.64e-04	188	65	4	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	COPD-Epithelial-Mesothelial\|COPD / Disease state, Lineage and Cell class	EGFR SLIT3 TMEM151A FHL2	1.67e-04	189	65	4	79bb2593ad5d17f94b17972884241f03a0f43770
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNGR1 P2RX1 DGKA KDM6B	1.67e-04	189	65	4	a1773ef8fe4518d8f3b17c6fb2c3ff3bbc4d79ad
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 FHL2 SEC14L5 ARAP2	1.67e-04	189	65	4	a75226616340045b581d08429d2e123e041dee55
ToppCell	droplet-Fat-Scat-21m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 CRIM1 TSPAN6 MCF2L	1.71e-04	190	65	4	d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCell	droplet-Fat-Scat-21m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTT2 CRIM1 TSPAN6 MCF2L	1.71e-04	190	65	4	dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL3 EGFR PI16 SLIT3	1.71e-04	190	65	4	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLIT3 FHL2 SEC14L5 ARAP2	1.71e-04	190	65	4	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 PI16 SLIT3 FHL2	1.74e-04	191	65	4	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPYSL3 EGFR PI16 SLIT3	1.78e-04	192	65	4	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 PI16 AIRE FHL2	1.78e-04	192	65	4	f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	IVNS1ABP DGKA SFI1 ARAP2	1.78e-04	192	65	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 PI16 AIRE FHL2	1.78e-04	192	65	4	41a8326cd5bc19ad5041068501bab4c72399222e
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPYSL3 EGFR PI16 SLIT3	1.78e-04	192	65	4	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	DPYSL2 P2RX1 TLR7 PLXNB2	1.85e-04	194	65	4	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	DPYSL3 EGFR PI16 KDM6B	1.85e-04	194	65	4	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.85e-04	194	65	4	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	facs-Mammary_Gland\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 DPYSL3 KDM6B FHL2	1.88e-04	195	65	4	21cfcb751e548591fc8724a8329c294da6012e0f
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 PI16 AIRE FHL2	1.88e-04	195	65	4	47762d9e442fb1f6f0033e3e10f4c6e498d2c081
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 P2RX1 SLIT3 FHL2	1.92e-04	196	65	4	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPYSL3 EGFR PI16 SLIT3	1.92e-04	196	65	4	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	IPF-Stromal-Fibroblast\|IPF / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3	1.92e-04	196	65	4	f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.92e-04	196	65	4	023477a499a2c190f363cfdbc9d9c646733a6541
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3	1.92e-04	196	65	4	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.92e-04	196	65	4	3cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 P2RX1 SLIT3 FHL2	1.92e-04	196	65	4	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	1.92e-04	196	65	4	545d2e4469924d333e3f655f559c899fa1260196
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IVNS1ABP CRIM1 TSPAN6 FHL2	1.96e-04	197	65	4	8786125b669d5d0b15e12df0ade6b319f09f7333
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3	1.96e-04	197	65	4	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	facs-Diaphragm-Limb_Muscle-3m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNGR1 DPYSL2 EGFR RLIM	1.96e-04	197	65	4	b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCell	COPD-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3	2.00e-04	198	65	4	2f13c0b3372af53d1bd85f9546f315c878580a71
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-Treg\|Influenza_Severe / Disease, condition lineage and cell class	TRIM66 PI16 TRMT13 MCF2L	2.00e-04	198	65	4	e377fa0215f338f86ee2903ce3fa57cea805a630
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IVNS1ABP CRIM1 TSPAN6 FHL2	2.00e-04	198	65	4	3575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCell	COPD-Stromal-Fibroblast\|COPD / Disease state, Lineage and Cell class	DPYSL3 EGFR PI16 SLIT3	2.00e-04	198	65	4	7904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	2.04e-04	199	65	4	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IVNS1ABP IFNGR1 EGFR DGKA	2.04e-04	199	65	4	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYSL3 CRIM1 SLIT3 FHL2	2.04e-04	199	65	4	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	control-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IVNS1ABP IFNGR1 EGFR DGKA	2.04e-04	199	65	4	3d01f90ffd271ca00129192787e4921bdca7e01e
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	IVNS1ABP IFNGR1 EGFR DGKA	2.04e-04	199	65	4	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPYSL3 DHH RECQL4 SLIT3	2.04e-04	199	65	4	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Biopsy_Other_PF-Mesenchymal-Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	DPYSL3 PI16 SLIT3 FHL2	2.08e-04	200	65	4	9996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCell	Skin-Fibroblasts\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	DPYSL2 DPYSL3 PI16 SLIT3	2.08e-04	200	65	4	f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLIT3 FHL2 SEC14L5 ARAP2	2.08e-04	200	65	4	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	DPYSL3 DHH MCF2L LRP1B	2.08e-04	200	65	4	e5f876910bc8cb390d9b46a48d9b6d4d57235551
Computational	Developmental processes.	DPYSL2 DPYSL3 DHH RECQL4 SLIT3 CD40 DPYSL4	2.73e-04	333	42	7	MODULE_220
Drug	2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA	EGFR PRICKLE3 CD40 DGKA DPYSL4 GYG2	1.66e-05	189	65	6	989_UP
Drug	Beclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; PC3; HT_HG-U133A	EGFR MTMR3 DPYSL4 SFI1 KDM6B ZNF639	1.76e-05	191	65	6	4580_UP
Drug	2-propylpentanoic acid; Up 200; 500uM; MCF7; HT_HG-U133A	PRICKLE3 RHOBTB2 DPYSL4 GYG2 SFI1 MCF2L	1.98e-05	195	65	6	6999_UP
Drug	Econazole nitrate [24169-02-6]; Up 200; 9uM; HL60; HT_HG-U133A	CRIM1 PRICKLE3 RAB3GAP2 MTMR3 PHTF2 SFI1	1.98e-05	195	65	6	2396_UP
Drug	DO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A	PRICKLE3 NLRX1 TRIM62 PHTF2 DPYSL4 GYG2	2.16e-05	198	65	6	2877_DN
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; MCF7; HT_HG-U133A	NLRX1 CD40 DPYSL4 GYG2 KDM6B ZNF639	2.22e-05	199	65	6	7172_UP
Disease	Charcot-Marie-Tooth disease (biomarker_via_orthology)	GSTT2 GSTT2B	4.34e-06	2	62	2	DOID:10595 (biomarker_via_orthology)
Disease	breast carcinoma (is_marker_for)	KMT2D EGFR KDM6B EP300	1.15e-05	66	62	4	DOID:3459 (is_marker_for)
Disease	pulse pressure measurement	TRIM66 HGFAC MALRD1 CRIM1 ANKUB1 SLIT3 PHTF2 KDM6B MCF2L FHL2 PLXNB2	1.37e-04	1392	62	11	EFO_0005763
Disease	glioblastoma multiforme	POLR3B EGFR	1.55e-04	9	62	2	EFO_0000519
Disease	primary bacterial infectious disease (implicated_via_orthology)	DHH SHH	1.55e-04	9	62	2	DOID:0050338 (implicated_via_orthology)
Disease	asthma (biomarker_via_orthology)	EGFR CD40 MUC5AC	2.64e-04	59	62	3	DOID:2841 (biomarker_via_orthology)
Disease	3-formylindole measurement	GSTT2 GSTT2B	3.34e-04	13	62	2	EFO_0801025
Disease	serum alanine aminotransferase measurement	HGFAC LDLRAD1 CRIM1 RHOBTB2 RECQL4 SHH PLXNB2 GSTT2B	4.54e-04	869	62	8	EFO_0004735
Disease	T-Cell Lymphoma	KMT2D EP300	5.11e-04	16	62	2	C0079772
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	CD40 TLR7	5.79e-04	17	62	2	DOID:8677 (biomarker_via_orthology)
Disease	bipolar disorder, sex interaction measurement	SLIT3 FHL2	6.50e-04	18	62	2	EFO_0008343, MONDO_0004985
Disease	Squamous cell carcinoma of esophagus	KMT2D EGFR EP300	1.07e-03	95	62	3	C0279626
Disease	susceptibility to pneumonia measurement	MALRD1 PLXNB2 MUC5AC	1.13e-03	97	62	3	EFO_0008410
Disease	chronic obstructive pulmonary disease (is_marker_for)	EGFR CD40 MUC5AC	1.13e-03	97	62	3	DOID:3083 (is_marker_for)
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	SLIT3 EP300	1.16e-03	24	62	2	DOID:3827 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	KMT2D EGFR PRICKLE3 CD40 MTMR3 FHL2 ZDHHC4 EP300	1.78e-03	1074	62	8	C0006142
Disease	central nervous system cancer	POLR3B EGFR	1.94e-03	31	62	2	EFO_0000326
Disease	sleep quality	POLR3B PRSS38 LRP1B	1.99e-03	118	62	3	EFO_0005272

Protein segments in the cluster

Peptide	Gene	Start	Entry
WHHEREHYNLSAATC	PI16	106	Q6UXB8
SESWENHTTCQHCYR	ZNF280D	351	Q6N043
HVETRWHCTVCEDYD	EP300	1676	Q09472
WHLGLSCASRNDHCY	ARSH	116	Q5FYA8
DPETHCHAERCFLSW	APOBEC3D	256	Q96AK3
SCCDYALHVDITHWN	DPYSL3	131	Q14195
LTAYSEKHHWHLCCD	ARAP2	1506	Q8WZ64
CWSGFHIIFERLCSH	ASB6	296	Q9NWX5
TDVLRCTHCAAAFHW	AIRE	441	O43918
SLELDVLHAHCCWEY	RAB3GAP2	1006	Q9H2M9
EFLCHDHVTCVSQSW	LRP1B	36	Q9NZR2
CLRTVECYNPHTDHW	IVNS1ABP	381	Q9Y6Y0
SCCDYSLHVDISEWH	DPYSL2	131	Q16555
YWTCRDHALHGCRSR	FLYWCH1	301	Q4VC44
HYWETISAFCDRHGV	KDM6B	1416	O15054
RHPYLRSCCHLENTW	FBXW12	411	Q6X9E4
TCQWDLRYHECREAS	PLXNB2	636	O15031
IYHSLTGLHCVWCHL	DGKA	291	P23743
CRDHVQHCSDWSDEY	LDLRAD1	186	Q5T700
DYSLICWHHICSVLT	NLRP4	621	Q96MN2
YAALCASHDICIDWR	MUC5AC	5191	P98088
PSYCWLVCATLHFLH	NLRX1	371	Q86UT6
NEYWVLSAAHCFHRD	PRSS38	91	A1L453
ARARVHEYLGWHADC	GSTT2B	91	P0CG30
LVHTCWVVSAAHCFS	HGFAC	436	Q04756
AYEGQHWHASDRCFC	PRICKLE3	326	O43900
HCWTLTHYSKCVFLD	GYG2	121	O15488
ESCEGLDHFWCRHTR	MALRD1	821	Q5VYJ5
ACCDYSLHVDITRWH	DPYSL4	131	O14531
LVWKYADAGHVCHLC	EGFR	606	P00533
ASCYAVLESHQWAHR	DHH	341	O43323
ARARVHEYLGWHADC	GSTT2	91	P0CG29
YADEERWDLDSCTHC	CRIM1	826	Q9NZV1
YKDRHWHEACFHCSQ	FHL2	56	Q14192
DYCHSRWLCQRTAIE	MCF2L	221	O15068
RCHYAWAHDDISALT	FIGNL2	41	A6NMB9
HCSYTVHPENEDWTC	SEC14L5	111	O43304
SEWIDACINISHHYC	IFNGR1	71	P15260
WLPDHLAAHCYACDS	MTMR3	1116	Q13615
TIDWHCDLDWHVRHC	P2RX1	256	P51575
CDLDWHVRHCRPIYE	P2RX1	261	P51575
QHEWKLCVRADCHYR	SFI1	136	A8K8P3
LWEDLLHCAECHSSC	PHTF2	406	Q8N3S3
VIALCCHHRCDWRHY	TRMT13	331	Q9NUP7
ASCYAVIEEHSWAHR	SHH	361	Q15465
FACIDEAHCLSQWSH	RECQL4	601	O94761
VCISFSICHTFRWHE	HCAR3	176	P49019
FHCAYQLADWCLHHI	RHOBTB2	621	Q9BYZ6
LLYLAECWHCHVRSC	TMEM151A	111	Q8N4L1
PYRAWCHEALHADVS	ANKUB1	226	A6NFN9
RLHSNHLYCDCHLAW	SLIT3	211	O75094
DTHFSDHLYWCEQCD	ZNF639	281	Q9UID6
PYCHLLDSSHWAEIC	RMND5B	251	Q96G75
LCSHIRWDAHNCDHS	SSC4D	551	Q8WTU2
LPCSHEYHVHCIDRW	RLIM	586	Q9NVW2
SVCNWCVHRFDHHCV	ZDHHC4	166	Q9NPG8
LHCCGVTDYRDWTDT	TSPAN6	151	O43657
WCHYCKSSCHVSSLR	POLR3B	1091	Q9NW08
HHNRFLCTCDAVWFV	TLR7	781	Q9NYK1
WEYRSGRQLHCCHLA	WDR4	216	P57081
CNRWLCSSCTEEHRH	TRIM66	21	O15016
CEHYFCRRCITEHWV	TRIM62	26	Q9BVG3
FDYVWLRDHCRSASC	TMLHE	71	Q9NVH6
LHDSLHDCSHWFYTR	ZRANB1	466	Q9UGI0
WNRETHCHQHKYCDP	CD40	71	P25942
NSEWFENYSLCHRCH	KMT2D	336	O14686