Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopolyphosphatase activity

NUDT11 NUDT3 NUDT10

4.71e-0651573GO:0000298
GeneOntologyMolecularFunctionbis(5'-adenosyl)-hexaphosphatase activity

NUDT11 NUDT3 NUDT10

4.71e-0651573GO:0034431
GeneOntologyMolecularFunctiondiphosphoinositol-polyphosphate diphosphatase activity

NUDT11 NUDT3 NUDT10

4.71e-0651573GO:0008486
GeneOntologyMolecularFunctionbis(5'-adenosyl)-pentaphosphatase activity

NUDT11 NUDT3 NUDT10

9.37e-0661573GO:0034432
GeneOntologyMolecularFunctionGTPase binding

DOCK1 PPP1R9A PLEKHG3 RABGAP1L CDC42EP2 AKAP13 FGD5 RAB11FIP4 GOLGA4 PKN3 SORL1

1.35e-0436015711GO:0051020
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 ARHGEF12 ARHGAP4 PLEKHG3 RABGAP1L EIF2B5 CDC42EP2 KIAA1755 AKAP13 SH3BP5L FGD5 PLXNB1 TBCD

1.91e-0450715713GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 ARHGEF12 ARHGAP4 PLEKHG3 RABGAP1L EIF2B5 CDC42EP2 KIAA1755 AKAP13 SH3BP5L FGD5 PLXNB1 TBCD

1.91e-0450715713GO:0030695
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK1 PLEKHG3 RABGAP1L CDC42EP2 AKAP13 FGD5 RAB11FIP4 GOLGA4 PKN3 SORL1

2.34e-0432115710GO:0031267
GeneOntologyMolecularFunctiontranscription factor binding

SETD1A WIPI1 AKAP8 FLYWCH1 E4F1 ARID1A IKZF4 HNRNPU PASD1 ZNHIT6 PER2 ARNT2 DOT1L BSN LEF1 HDAC1

2.99e-0475315716GO:0008134
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 ARHGEF12 PLEKHG3 EIF2B5 KIAA1755 AKAP13 SH3BP5L FGD5

4.96e-042311578GO:0005085
GeneOntologyMolecularFunctionRNA cap binding

LARP1 NCBP3 EIF4A1

5.72e-04211573GO:0000339
GeneOntologyMolecularFunctiondATP binding

ST13 ST13P5

6.05e-0451572GO:0032564
GeneOntologyMolecularFunctionadenyl deoxyribonucleotide binding

ST13 ST13P5

9.03e-0461572GO:0032558
GeneOntologyMolecularFunctionhistone deacetylase binding

MIER2 MAGEA9 AKAP8 PER2 LEF1 HDAC1

1.09e-031471576GO:0042826
GeneOntologyMolecularFunctiontranscription corepressor binding

PER2 BSN LEF1 HDAC1

1.20e-03591574GO:0001222
GeneOntologyMolecularFunctionpurine deoxyribonucleotide binding

ST13 ST13P5

1.26e-0371572GO:0032554
GeneOntologyMolecularFunctionprotein domain specific binding

DOCK1 CACNB1 PPP1R9A BAK1 SKP1 ST13 IKZF4 AXIN1 AFAP1L1 EHD2 ZNF592 SAMD11 ROBO1 ST13P5 LEF1 HDAC1

1.48e-0387515716GO:0019904
GeneOntologyBiologicalProcessregulation of synapse assembly

DOCK1 PODXL PPP1R9A CRTAC1 CC2D1A PTPRD PTPRS PRKCA ROBO1 ADGRE5

3.49e-0620215710GO:0051963
GeneOntologyBiologicalProcessadenosine 5'-(hexahydrogen pentaphosphate) metabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901910
GeneOntologyBiologicalProcessadenosine 5'-(hexahydrogen pentaphosphate) catabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901911
GeneOntologyBiologicalProcessdiadenosine pentaphosphate catabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901907
GeneOntologyBiologicalProcessdiadenosine pentaphosphate metabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901906
GeneOntologyBiologicalProcessdiadenosine hexaphosphate catabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901909
GeneOntologyBiologicalProcessdiadenosine hexaphosphate metabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:1901908
GeneOntologyBiologicalProcessdiphosphoinositol polyphosphate metabolic process

NUDT11 NUDT3 NUDT10

4.28e-0651573GO:0071543
GeneOntologyBiologicalProcesssynapse assembly

DOCK1 PODXL PPP1R9A CRTAC1 CC2D1A PTPRD PTPRS PRKCA ROBO1 ADGRE5 BSN PLXNB1

4.39e-0630815712GO:0007416
GeneOntologyBiologicalProcessdiadenosine polyphosphate catabolic process

NUDT11 NUDT3 NUDT10

8.51e-0661573GO:0015961
GeneOntologyBiologicalProcessdiadenosine polyphosphate metabolic process

NUDT11 NUDT3 NUDT10

3.51e-0591573GO:0015959
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

DOCK1 ABCA3 WIPI1 PODXL PPP1R9A BAK1 CRTAC1 CC2D1A CEP192 HNRNPU PTPRD RNF5 TRAPPC12 PTPRS CDC42EP2 CHMP3 PRKCA ROBO1 ADGRE5 CX3CL1 TBCD SORL1

1.00e-04118915722GO:0044087
GeneOntologyBiologicalProcessregulation of cell junction assembly

DOCK1 PODXL PPP1R9A CRTAC1 CC2D1A PTPRD PTPRS PRKCA ROBO1 ADGRE5

1.33e-0430915710GO:1901888
GeneOntologyBiologicalProcessactivation of cysteine-type endopeptidase activity

BAD BAK1 NLRP6

1.84e-04151573GO:0097202
HumanPhenoAtrophic muscularis propria

POLG RRM2B TYMP

1.93e-064413HP:0025149
HumanPhenoAbnormal intestinal smooth muscle morphology

POLG RRM2B TYMP

1.93e-064413HP:0030935
HumanPhenoScoliosis

AMER1 PLOD3 USB1 PODXL POLG RRM2B FLVCR1 INTS1 WDR81 CHD3 ARID1A RYR1 RFWD3 HNRNPU FANCE ARVCF TRAPPC12 CC2D2A HSPB8 UNC80 TBCD KIF22

8.95e-0611224122HP:0002650
HumanPhenoSmall intestinal dysmotility

POLG RRM2B TYMP

9.52e-066413HP:0012850
HumanPhenoDecreased number of large peripheral myelinated nerve fibers

POLG RRM2B TYMP HSPB8

1.59e-0520414HP:0003387
HumanPhenoAbnormal curvature of the vertebral column

AMER1 PLOD3 USB1 PODXL POLG RRM2B FLVCR1 INTS1 WDR81 CHD3 ARID1A RYR1 RFWD3 HNRNPU FANCE ARVCF TRAPPC12 CC2D2A HSPB8 UNC80 TBCD KIF22

3.64e-0512194122HP:0010674
HumanPhenoReduced tissue thymidine phosphorylase activity

POLG TYMP

6.32e-052412HP:6000570
HumanPhenoElevated circulating deoxyuridine concentration

POLG TYMP

6.32e-052412HP:0034277
HumanPhenoElevated circulating thymidine concentration

POLG TYMP

6.32e-052412HP:0034276
HumanPhenoDecreased sensory nerve conduction velocity

POLG RRM2B FLVCR1 TYMP

6.43e-0528414HP:0003448
HumanPhenoAbnormal sensory nerve conduction velocity

POLG RRM2B FLVCR1 TYMP

7.42e-0529414HP:0040132
HumanPhenoMultiple mitochondrial DNA deletions

POLG RRM2B TYMP

7.64e-0511413HP:0003689
HumanPhenoGastroparesis

PODXL POLG RRM2B TYMP

1.41e-0434414HP:0002578
HumanPhenoHyperactive bowel sounds

POLG TYMP

1.89e-043412HP:0030143
HumanPhenoAbnormality of the bladder

POLG RRM2B FLVCR1 RYR1 RFWD3 HNRNPU FANCE ARVCF TRAPPC12 ARNT2 CC2D2A ROBO1 STRA6 TBCD

2.08e-046214114HP:0000014
HumanPhenoHypomimic face

PODXL POLG RRM2B CC2D1A

2.42e-0439414HP:0000338
HumanPhenoMacrovesicular hepatic steatosis

POLG RRM2B TYMP

3.04e-0417413HP:0001403
HumanPhenoAbnormal cerebrospinal fluid morphology

AMER1 POLG RRM2B WDR81 GCDH TYMP RFWD3 HNRNPU FANCE ARVCF TRAPPC12 EIF2B5 CC2D2A ROBO1

3.16e-046464114HP:0002921
HumanPhenoAbnormal neurological laboratory findings

AMER1 POLG RRM2B FLVCR1 WDR81 GCDH TYMP RYR1 RFWD3 HNRNPU FANCE ARVCF TRAPPC12 EIF2B5 CC2D2A ROBO1 HSPB8 UNC80

3.28e-0410004118HP:0003129
HumanPhenoAbnormal tracheal morphology

AMER1 USB1 POLG RFWD3 FANCE ARNT2 KIF22

3.51e-04170417HP:0002778
HumanPhenoAbnormal cell morphology

POLG RRM2B TYMP RYR1

3.55e-0443414HP:0025461
HumanPhenoAbnormal circulating pyrimidine concentration

POLG TYMP FANCE

3.63e-0418413HP:0004353
HumanPhenoDepletion of mitochondrial DNA in muscle tissue

POLG RRM2B TYMP

4.29e-0419413HP:0009141
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

NUDT11 NUDT3 NUDT10

6.25e-05101163MM14709
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

NUDT11 NUDT3 NUDT10

6.25e-05101163M27051
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TFEB SETD1A PLOD3 POLG INTS1 PFAS CC2D1A CEP192 ARID1A BIRC6 RYR1 FAM83H PPP1R26 PER2 ARVCF ZNF592 TRAPPC12 PTPRS NLRC5 TP53I13 AKAP13 SH3BP5L DOT1L SYVN1 PKN3 TBCD

8.56e-1211051602635748872
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SECISBP2L NOL6 ZNF629 LARP1 PFAS CHD3 RFWD3 HNRNPU KLHL11 ZNHIT6 ARVCF EIF4A1 EIF2B5 AKAP13 PLXNB1 SORL1

6.24e-086501601638777146
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TFEB NES AMER1 USP22 AKAP8 BAD ZNF629 LARP1 CC2D1A CEP192 FAM83H SAMD11 PLEKHG3 RABGAP1L AKAP13 BOD1L1 SH3BP5L GOLGA4

1.04e-078611601836931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES CACNB1 NYAP2 AKAP8 PPP1R9A WDR81 ARHGEF12 PPFIA3 SKP1 FBXO2 HNRNPU UBE2O PTPRD ARVCF PTPRS EIF4A1 PRKCA BSN GOLGA4

1.10e-079631601928671696
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

DOCK1 AMER1 AKAP8 PFAS USP37 SKP1 HNRNPU FAM83H PER2 AKAP13

1.36e-072321601025515538
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP22 AKAP8 MAP1A ZNF212 RALYL ZNF629 APBA2 GCDH CHD3 PPFIA3 ARID1A SKP1 FAM83H ARHGAP4 ZNHIT6 ZNF592 UNC80 INO80B HDAC1 SORL1

2.32e-0711161602031753913
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

NES AKAP8 WDR33 LARP1 BIRC6 AFAP1L1 UBE2O CUEDC2 TRAPPC12 ARNT2 ROBO1 AKAP13 BOD1L1 SH3BP5L GOLGA4 PKN3

3.14e-077331601634672954
Pubmed

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.

NUDT11 NUDT3 NUDT10

3.81e-074160312370170
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TFEB MAP1A WDR33 ZNF629 BAK1 PFAS CEP192 ARID1A SKP1 ST13 SH3BP5L DOT1L BSN SORL1

6.43e-075881601438580884
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

PODXL INTS1 PFAS GCDH AFAP1L1 PPP1R26 ARHGAP4 UBE2O ZNHIT6 TRAPPC12 EIF2B5 AKAP13 FGD5 TBCD KIF22

7.74e-076891601536543142
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRS BSN

9.49e-075160322357843
Pubmed

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

AMER1 SKP1 AXIN1 LEF1

9.80e-0717160417510365
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

AMER1 PLOD3 WDR33 BAD LARP1 FBXO11 PFAS ARID1A SKP1 AXIN1 HNRNPU FAM83H NUDT11 ARVCF EIF4A1 ZNF511 DOT1L LEF1 HDAC1 KIF22

1.30e-0612471602027684187
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

EXOSC10 AKAP8 NOL6 ZNF629 LARP1 FBXO11 CHD3 BIRC6 HNRNPU NCBP3 EIF4A1 EIF2B5 DGCR8 HDAC1 KIF22

2.54e-067591601535915203
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TFEB EXOSC10 AKAP8 FLYWCH1 WDR33 INTS1 FNBP4 ZNF629 FBXO11 CHD3 NCAPH2 E4F1 ARID1A SKP1 RFWD3 HNRNPU PWWP2A HDAC1 KIF22

8.64e-0612941601930804502
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SETD1A ZNF629 ARHGEF12 PFAS PER2 ARNT2

9.03e-0610416069205841
Pubmed

DNA damage-induced activation of ATM promotes β-TRCP-mediated ARID1A ubiquitination and destruction in gastric cancer cells.

ARID1A SKP1 FBXO2

1.12e-0510160331210753
Pubmed

FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.

FBXO11 SKP1 NLRC5

1.53e-0511160337279268
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

NES APBA2 ARHGEF12 ITIH2 NUDT11 ARVCF NUDT10 CHMP3

1.98e-05246160815345747
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

SETD1A AKAP8 FBXO11 CHD3 SKP1 FBXO2 PWWP2A UBE2O BOD1L1 INO80B HDAC1

2.01e-054951601127705803
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PPFIA3 PTPRD PTPRS

2.04e-051216039624153
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PPP1R9A ARHGEF12 CEP192 TRIL PER2 RABGAP1L BOD1L1 SH3BP5L RAB11FIP4 SYVN1

2.07e-054071601012693553
Pubmed

BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A.

SETD1A BOD1L1

2.10e-052160238989615
Pubmed

Interplay between DOT1L and HDAC1 regulates Leishmania donovani infection in human THP-1 cells.

DOT1L HDAC1

2.10e-052160239103111
Pubmed

DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs.

EXOSC10 DGCR8

2.10e-052160226687677
Pubmed

Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.

NUDT11 NUDT10

2.10e-052160212689335
Pubmed

Energetics of OCP1-OCP2 complex formation.

SKP1 FBXO2

2.10e-052160218284940
Pubmed

An α-helical C-terminal tail segment of the skeletal L-type Ca2+ channel β1a subunit activates ryanodine receptor type 1 via a hydrophobic surface.

CACNB1 RYR1

2.10e-052160222962299
Pubmed

A novel F box protein, NFB42, is highly enriched in neurons and induces growth arrest.

SKP1 FBXO2

2.10e-05216029857061
Pubmed

Modulation of p120E4F transcriptional activity by the Gam1 adenoviral early protein.

E4F1 HDAC1

2.10e-052160212730668
Pubmed

St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis.

ST13 ST13P5

2.10e-052160235562743
Pubmed

An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

NUDT11 NUDT10

2.10e-052160212105228
Pubmed

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

DOT1L HDAC1

2.10e-052160231304633
Pubmed

Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β1a Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal Myotubes.

CACNB1 RYR1

2.10e-052160226114725
Pubmed

Mitochondrial Neurogastrointestinal Encephalopathy Disease

POLG TYMP

2.10e-052160220301358
Pubmed

Positive association of CC2D1A and CC2D2A gene haplotypes with mental retardation in a Han Chinese population.

CC2D1A CC2D2A

2.10e-052160222023432
Pubmed

Identifying and treating ROBO1-ve /DOCK1+ve prostate cancer: An aggressive cancer subtype prevalent in African American patients.

DOCK1 ROBO1

2.10e-052160232687658
Pubmed

Amino acid residues 489-503 of dihydropyridine receptor (DHPR) β1a subunit are critical for structural communication between the skeletal muscle DHPR complex and type 1 ryanodine receptor.

CACNB1 RYR1

2.10e-052160225384984
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

2.10e-05216029566880
Pubmed

Erythropoietin modulation of podocalyxin and a proposed erythroblast niche.

EPOR PODXL

2.10e-052160217403918
Pubmed

Active Bax and Bak are functional holins.

BAD BAK1

2.10e-052160222006182
Pubmed

Structural basis for the selection of glycosylated substrates by SCF(Fbs1) ubiquitin ligase.

SKP1 FBXO2

2.10e-052160217389369
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

EXOSC10 AKAP8 NOL6 FNBP4 LARP1 CHD3 ARID1A HNRNPU NCBP3 ZNF592 EIF4A1 HDAC1

2.57e-056051601228977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MIER2 FLYWCH1 INTS1 CHD3 NCBP3 PWWP2A UBE2O ZNF592 BOD1L1 DOT1L HDAC1 KIF22

2.70e-056081601236089195
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

DOCK1 AMER1 USP37 SKP1 AXIN1 HNRNPU

2.95e-05128160625332235
Pubmed

Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model.

NES DGCR8 LEF1

3.35e-0514160324101523
Pubmed

FBH1 promotes DNA double-strand breakage and apoptosis in response to DNA replication stress.

FBXO11 SKP1 FBXO2

3.35e-0514160323319600
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1A NYAP2 FLYWCH1 ZNF212 FNBP4 LARP1 ARHGAP4 UBE2O ZNF592 BSN PLXNB1

3.68e-055291601114621295
Pubmed

Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.

NES ARVCF PRKCA DGCR8

3.83e-0541160425452572
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

TFEB AKAP8 ARID1A HNRNPU HDAC1 KIF22

3.97e-05135160631077711
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SETD1A EXOSC10 PLOD3 AKAP8 RRM2B NOL6 FNBP4 LARP1 ARID1A ZNF592

4.00e-054401601034244565
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

PLOD3 AKAP8 PPP1R9A ZNF629 LARP1 HNRNPU NCBP3 EIF4A1

4.26e-05274160834244482
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

BAD ARHGEF12 ARHGAP4 AKAP13

4.63e-0543160412376548
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

DOCK1 WDR81 NUDT11 NUDT10 NLRC5 UNC80 HDAC1

4.86e-05205160712040188
Pubmed

Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina.

NES PTPRS PRKCA

5.12e-0516160318308476
Pubmed

Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).

CHD3 ARID1A HDAC1

5.12e-0516160311784859
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A EXOSC10 WDR33 FNBP4 LARP1 CC2D1A ARID1A UBE2O BOD1L1 DOT1L HDAC1

5.14e-055491601138280479
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETD1A NES EXOSC10 NOL6 PFAS ARID1A SKP1 BIRC6 HNRNPU FAM83H ARVCF PLEKHG3 EIF4A1 EIF2B5 PRKCA AKAP13 HSPB8 GOLGA4

5.49e-0513531601829467282
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MAP1A ARHGEF12 PFAS CEP192 AXIN1 UBE2O ROBO1

5.49e-05209160736779422
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 AMER1 POLG FLVCR1 PPP1R9A BAD FNBP4 LARP1 CHD3 CEP192 ARID1A HNRNPU PTPRS PLEKHG3 NLRC5 AKAP13 BOD1L1 GOLGA4 TBCD

5.87e-0514891601928611215
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

DOCK1 AKAP8 RALYL INTS1 LARP1 FBXO11 GCDH HNRNPU NCBP3 DGCR8

6.00e-054621601031138677
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

NES PTPRD PTPRS

6.20e-0517160319727691
Pubmed

Clinical, pathological and genetic spectrum in 89 cases of mitochondrial progressive external ophthalmoplegia.

POLG RRM2B

6.29e-053160232161153
Pubmed

Comparison of E-cadherin with STAT3 and apoptosis regulators: Bak and Bcl-xL in endometrioid adenocarcinomas of different ER-alpha immunoprofile.

BAD BAK1

6.29e-053160228937296
Pubmed

Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator.

LEF1 HDAC1

6.29e-053160210958684
Pubmed

Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors.

ARHGEF12 PLXNB1

6.29e-053160212220504
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRS

6.29e-053160231985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRS

6.29e-053160220139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRS

6.29e-053160233656439
Pubmed

Interaction between the dihydropyridine receptor Ca2+ channel beta-subunit and ryanodine receptor type 1 strengthens excitation-contraction coupling.

CACNB1 RYR1

6.29e-053160216357209
Pubmed

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.

ARHGEF12 PLXNB1

6.29e-053160212196628
Pubmed

Mito-protective autophagy is impaired in erythroid cells of aged mtDNA-mutator mice.

EPOR POLG

6.29e-053160225411424
Pubmed

Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.

LEF1 HDAC1

6.29e-053160220363964
Pubmed

DNA damage regulates ARID1A stability via SCF ubiquitin ligase in gastric cancer cells.

ARID1A SKP1

6.29e-053160226400522
Pubmed

The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.

ARHGAP4 ROBO1

6.29e-053160226365803
Pubmed

X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer.

AXIN1 HDAC1

6.29e-053160223110995
Pubmed

Rapamycin-enhanced mitomycin C-induced apoptotic death is mediated through the S6K1-Bad-Bak pathway in peritoneal carcinomatosis.

BAD BAK1

6.29e-053160224901052
Pubmed

Kaiso is a bimodal modulator for Wnt/beta-catenin signaling.

AXIN1 HDAC1

6.29e-053160219166851
Pubmed

Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction coupling.

CACNB1 RYR1

6.29e-05316028943043
Pubmed

Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.

SKP1 FBXO2

6.29e-053160232931479
Pubmed

The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.

SKP1 FBXO2

6.29e-053160226460611
Pubmed

LEF-1 activates the transcription of E2F1.

LEF1 HDAC1

6.29e-053160217980157
Pubmed

Mouse models of age-related mitochondrial neurosensory hearing loss.

POLG BAK1

6.29e-053160222820179
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRS

6.29e-05316029784606
Pubmed

A Novel Naphthalimide Compound Restores p53 Function in Non-small Cell Lung Cancer by Reorganizing the Bak·Bcl-xl Complex and Triggering Transcriptional Regulation.

BAD BAK1

6.29e-053160226668309
Pubmed

M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression.

BAD BAK1

6.29e-053160216978419
Pubmed

Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families.

APOA5 SORL1

6.29e-053160218603531
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

6.29e-053160225394468
Pubmed

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.

NUDT11 NUDT10

6.29e-053160212121577
Pubmed

ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.

ARID1A HDAC1

6.29e-053160231913353
Pubmed

The cochlear F-box protein OCP1 associates with OCP2 and connexin 26.

SKP1 FBXO2

6.29e-053160215109709
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EXOSC10 AMER1 AKAP8 PODXL FLVCR1 NOL6 CC2D1A CEP192 BIRC6 CDC42EP2 ROBO1 DGCR8 GOLGA4

6.77e-057771601335844135
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK1 NES WDR33 ARHGEF12 SKP1 ST13 ARHGAP4 PLEKHG3 ROBO1 AKAP13 FGD5 GOLGA4 PKN3 SORL1

9.25e-059161601432203420
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

POLG APBA2 FBXO11 CRTAC1 NCAPH2 CLIC6 ARID1A ST13 CREBZF UBE2O PTPRD ZNF592 EIF4A1 CHMP3 ROBO1 DGCR8 RAB11FIP4

9.55e-0512851601735914814
Pubmed

The protein interaction landscape of the human CMGC kinase group.

TFEB CACNB1 AKAP8 WDR33 WDR81 LARP1 SKP1 AXIN1 NCBP3 DGCR8 JHY SORL1

9.66e-056951601223602568
Pubmed

Functional proteomics mapping of a human signaling pathway.

USB1 FNBP4 CHD3 E4F1 ST13 CREBZF PPP1R26 ZNHIT6 ZNF592 CHMP3 TBCD

9.87e-055911601115231748
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L MIER2 ZNF629 PFAS USP37 BIRC6 PPP1R26 PWWP2A PLEKHG3 UNC80

1.02e-044931601015368895
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PLOD3 FLVCR1 PPP1R9A PFAS CEP192 PPFIA3 ARID1A SKP1 BIRC6 PTPRD ARVCF PTPRS ROBO1 GOLGA4 KIF22

1.08e-0410491601527880917
Pubmed

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.

AKAP8 LARP1 HNRNPU NCBP3

1.23e-0455160431640799
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

SECISBP2L AMER1 PLOD3 AKAP8 PFAS GCDH NCAPH2 SKP1 FAM83H PKN3 TBCD

1.23e-046061601136538041
InteractionPLD1 interactions

MIER2 MAGEA9 APBA2 UBE2O PER2 EIF2B5 PRKCA DOT1L PKN3

9.21e-071301599int:PLD1
InteractionTOP3B interactions

TFEB SETD1A PLOD3 POLG RRM2B PPP1R9A INTS1 PFAS CC2D1A CEP192 ARID1A BIRC6 RYR1 HNRNPU FAM83H PPP1R26 PER2 ARVCF ZNF592 TRAPPC12 PTPRS EIF4A1 NLRC5 TP53I13 AKAP13 SH3BP5L DOT1L SYVN1 PKN3 TBCD

1.29e-06147015930int:TOP3B
InteractionNXF1 interactions

NES EXOSC10 USP22 AKAP8 MAP1A WDR33 PODXL NOL6 RALYL FNBP4 WDR81 PFAS CHD3 CEP192 XPNPEP1 SSR2 ARID1A CREBZF RFWD3 NCBP3 PPP1R26 TBCCD1 UBE2O NUDT3 RABGAP1L PRKCA HDAC1 KIF22

2.11e-06134515928int:NXF1
Cytoband1p36.22

EXOSC10 C1orf167 FBXO2

2.96e-043716031p36.22
CytobandXp11.23

GAGE2A GAGE2B NUDT10 CHST7

3.53e-04951604Xp11.23
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R9A WDR81 CEP192 RYR1 AXIN1 PPP1R26 MYO16

9.50e-051811067694
GeneFamilyNudix hydrolase family

NUDT11 NUDT3 NUDT10

3.62e-04241063667
GeneFamilyZinc fingers HIT-type

ZNHIT6 INO80B

5.03e-046106283
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 PLEKHG3 AKAP13 FGD5

6.08e-04661064722
GeneFamilyC2 domain containing protein kinases

PRKCA PKN3

1.49e-03101062835
GeneFamilyPHD finger proteins|NuRD complex

CHD3 HDAC1

2.16e-031210621305
GeneFamilyFibronectin type III domain containing

EPOR PTPRD PTPRS ROBO1 SORL1

2.52e-031601065555
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

TYMP AKAP13 PKN3

3.33e-03511063870
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

FLYWCH1 BSN

3.40e-0315106226
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15

EPOR E4F1 PTPRD ROBO1 KIF22

2.50e-06361595MM1284
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 TRIL CDC42EP2 FGD5 PKN3

4.61e-0719315885d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 TRIL CDC42EP2 FGD5 PKN3

4.61e-07193158895e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 TRIL CDC42EP2 FGD5 PKN3

4.61e-07193158897c0730aad9135ac681250b3871cc094a28f80a7
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FNBP4 APBA2 CHD3 HNRNPU ZNHIT6 PRKCA LEF1 SORL1

4.98e-071951588d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

AMER1 TBCCD1 NUDT11 PTPRS EIF2B5 CHST7 LEF1

4.32e-061841587ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.16e-06189158737ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.16e-061891587b55324cb365a827d071952709bbf0e8ef8c313de
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.16e-06189158762e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PODXL ARHGEF12 AFAP1L1 NLRC5 FGD5 CX3CL1 PKN3

5.72e-061921587c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C PODXL RALYL CRTAC1 ROBO1 FGD5 HSPB8

5.72e-06192158752acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C PODXL RALYL CRTAC1 SAMD11 FGD5 PKN3

5.72e-061921587717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PODXL ARHGEF12 AFAP1L1 NLRC5 FGD5 CX3CL1 HSPB8

5.92e-061931587a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NES PODXL AFAP1L1 EHD2 CDC42EP2 CX3CL1 HSPB8

5.92e-061931587aaf681f16f310168e4719464814a1fc0a2f8431a
ToppCellcritical-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PODXL CHD3 SSR2 ZNHIT6 PER2 CHMP3 SORL1

6.55e-061961587dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

FLYWCH1 APBA2 PFAS CLIC6 PLEKHG3 RABGAP1L LEF1

7.23e-06199158733ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CACNB1 ABCA3 AMER1 E4F1 C1orf167 NLRP6

2.01e-051561586fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

INTS1 APBA2 CC2D1A NLRC5 HEMK1 LEF1

2.40e-0516115862fe77af3b41e6eacb707a64feea18f9991618173
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ABCA3 PTPRD PTPRS RABGAP1L ARNT2 CC2D2A

3.04e-051681586c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP22 PFAS TYMP BIRC6 NUDT3 SORL1

3.36e-051711586c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

APBA2 CRTAC1 EHD2 FANCE KLHL11 PTPRS

3.59e-051731586ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ABCA3 APBA2 FBXO2 EHD2 FANCE PTPRS

3.71e-051741586110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES NYAP2 PODXL CDC42EP2 FGD5 PKN3

4.48e-051801586f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

MIER2 NES PODXL AFAP1L1 CX3CL1 PKN3

4.48e-051801586162cec1734e560c068cd61717e40e18dcf92308c
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES NYAP2 PODXL CDC42EP2 FGD5 PKN3

4.48e-05180158653db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES NYAP2 PODXL CDC42EP2 FGD5 PKN3

4.48e-05180158628bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

MIER2 NES PODXL AFAP1L1 CX3CL1 PKN3

4.48e-05180158633c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

NES PODXL ARHGEF12 AFAP1L1 FGD5 CX3CL1

4.62e-051811586c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITIH2 NUDT11 PTPRD ARNT2 NUDT10 MAP3K15

4.76e-051821586f5f42e23832d0210560009ce6fd8eee89751e252
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

NES PODXL AFAP1L1 FGD5 CX3CL1 PKN3

5.37e-051861586c6075fe84226b370c5139066793844ad33ae2db1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PODXL HERC2P3 AFAP1L1 NLRC5 LEF1 PKN3

5.37e-051861586422d24e3e1a9397bb7d5c7ef75de2fd7ae8e136d
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NES MAP1A NOL6 APBA2 PTPRS UNC80

5.37e-05186158610565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PODXL HERC2P3 AFAP1L1 NLRC5 LEF1 PKN3

5.37e-05186158665da0666a10a59f8cc379589860a2e98fe487754
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PODXL HERC2P3 AFAP1L1 NLRC5 LEF1 PKN3

5.37e-051861586dc84fef1ca2f5d5d818b76a3321559e87d1c4a4d
ToppCellfacs-Aorta-Heart-3m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL SYCE1L AFAP1L1 EHD2 FGD5

5.53e-051871586df0279b7e94e26f5541b0e2a0ce56befa96ec8ca
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB7C MAP1A PODXL EHD2 FGD5 PKN3

5.53e-051871586e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ZBTB7C PODXL EHD2 FGD5 PKN3

5.70e-051881586ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL EHD2 FGD5 LEF1 PKN3

5.70e-05188158667c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L MAP1A CRTAC1 PTPRD RNF5 CDC42EP2

5.70e-05188158687fd5e2dd01583baf7e018bff8750d20a557a20f
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

WIPI1 TRIL PTPRD PTPRS ROBO1 LEF1

5.70e-0518815863f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 CDC42EP2 FGD5 PKN3

5.70e-05188158605de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

NES PODXL AFAP1L1 CDC42EP2 FGD5 CX3CL1

5.70e-051881586fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

NES PODXL AFAP1L1 CDC42EP2 FGD5 CX3CL1

5.70e-051881586cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL EHD2 FGD5 LEF1 PKN3

5.70e-05188158603a7f6538cfddc230c0eab10c3613929addd7e33
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.87e-051891586a3f6ebd1622d36d114e42f6e0618d7b2fe8b9a2f
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.87e-051891586d86455cf20769d70d62e2c1dd92cbc93c67aada5
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 CDC42EP2 FGD5 PKN3

5.87e-0518915868ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L MAP1A CRTAC1 PTPRD RNF5 CDC42EP2

5.87e-051891586bab0fe55643d3ee750355a32b1ff6634fa5cf88d
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES PODXL AFAP1L1 CDC42EP2 FGD5 PKN3

5.87e-051891586403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCelldroplet-Limb_Muscle-nan-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 CDC42EP2 FGD5 PKN3

5.87e-05189158684036d1257f6b18f47cfc7ac5e6ed6ea3553c235
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 TRIL FGD5 PKN3

6.04e-051901586b7fc451e160e31dc898b122de844b501f587db67
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 TRIL FGD5 PKN3

6.04e-05190158683cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CEP192 RFWD3 DGCR8 PKN3 TBCD KIF22

6.04e-051901586d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODXL AFAP1L1 EHD2 TRIL FGD5 PKN3

6.04e-0519015865f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

NES PODXL AFAP1L1 FGD5 CX3CL1 PKN3

6.40e-0519215861e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZBTB7C PODXL RALYL CRTAC1 FGD5 CHST7

6.40e-05192158681baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SECISBP2L MAP1A FBXO2 PTPRD RNF5 CDC42EP2

6.59e-0519315864274c95cedad2ae8c6693ad00deda2b1ba5b5682
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

NES PODXL AFAP1L1 FGD5 CX3CL1 PKN3

6.59e-05193158639c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CEP192 RFWD3 PRKCA PKN3 TBCD KIF22

6.59e-0519315864b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell(6)_Endothelial-B_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NES PODXL PPFIA3 AFAP1L1 CX3CL1 PKN3

6.78e-0519415860cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

FLYWCH1 PPFIA3 UBE2O BSN CX3CL1 UNC80

6.78e-0519415868aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PODXL ARHGEF12 HERC2P3 AFAP1L1 FGD5 LEF1

6.78e-051941586ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PODXL ARHGEF12 HERC2P3 AFAP1L1 FGD5 LEF1

6.78e-051941586cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L ABCA3 PPP1R9A CRTAC1 AKAP13 GOLGA4

7.18e-0519615867e5addaa844e66f8160e05858c341866a80aed23
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

DOCK1 NES PODXL AFAP1L1 FGD5 CX3CL1

7.18e-05196158614dd6956ef420b660be0baf52a66960e57d75d16
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NES PODXL CRTAC1 ARHGAP4 NUDT10 FGD5

7.59e-051981586f88198e11e835ad53d339c312f8f7b7b0b5c02d3
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

APBA2 SKP1 NLRP6 PRKCA LEF1 SORL1

7.59e-051981586db107a5511571384f26e26c6301aef9a9f2423c4
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MIER2 NES PODXL AFAP1L1 CDC42EP2 CX3CL1

7.80e-0519915869364199c5b4540ce2e14341fd9d504b695f8249d
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NES PODXL AFAP1L1 EHD2 CX3CL1 HSPB8

7.80e-0519915867ed541309808f15d65a9c4b26be2050e077539e6
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1A PTPRD PTPRS ARNT2 ROBO1 PLXNB1

7.80e-0519915865d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MIER2 NES PODXL AFAP1L1 CX3CL1 HSPB8

7.80e-0519915865f67ea58512856cbdcef759088a5869720a947a8
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1A PTPRD PTPRS ARNT2 ROBO1 PLXNB1

7.80e-0519915869dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

FLYWCH1 APBA2 CLIC6 PLEKHG3 RABGAP1L LEF1

7.80e-051991586cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

FLYWCH1 APBA2 CLIC6 PLEKHG3 RABGAP1L LEF1

7.80e-051991586aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MIER2 NES PODXL AFAP1L1 CX3CL1 HSPB8

7.80e-05199158682758d0cee9387d002e3f68a6faa324134fb7564
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1A PTPRD PTPRS ARNT2 ROBO1 PLXNB1

7.80e-0519915866fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell10x_5'_v1-Non-neoplastic-Glial-Neuronal|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAP1A PTPRD PTPRS ARNT2 ROBO1 PLXNB1

7.80e-0519915861bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-052001586032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 NES PODXL AFAP1L1 CX3CL1 HSPB8

8.02e-052001586a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB7C PODXL CLIC6 ZNHIT6 PER2 CX3CL1

8.02e-052001586b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-05200158668fce28690246895fd33354b30960ebcc31aa4cc
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 NES PODXL AFAP1L1 CX3CL1 HSPB8

8.02e-0520015863ef7b7728615710c691aed8977e2582f19692cf9
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-052001586376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 NES PODXL EHD2 CX3CL1 HSPB8

8.02e-0520015867a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCelldistal-Endothelial-Capillary_Intermediate_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NES PODXL AFAP1L1 CDC42EP2 CX3CL1 HSPB8

8.02e-05200158643bc48413b100a06f8edd9acd812296788fcbf5b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm|6m / Sample Type, Dataset, Time_group, and Cell type.

NES CACNB1 C1orf167 RYR1 AFAP1L1 HSPB8

8.02e-0520015860f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-0520015867fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellmild-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

APBA2 CHD3 ST13 PRKCA ROBO1 LEF1

8.02e-052001586c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCelldistal-1-Endothelial-Capillary_Aerocyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 NES PODXL AFAP1L1 EHD2 CX3CL1

8.02e-05200158659bacd738433cec6d05624a25fdfc087fb3ca3b5
ToppCelldistal-Endothelial-Capillary_Intermediate_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NES PODXL AFAP1L1 CDC42EP2 CX3CL1 HSPB8

8.02e-0520015864d6714d48738cdee7d535923f6dd2431e5304741
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-052001586878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 PODXL EHD2 ARNT2 KIAA1755 LEF1

8.02e-0520015867136936d05ab344a560cf159684c881063b5430d
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 NES PODXL AFAP1L1 CX3CL1 HSPB8

8.02e-052001586707148e01e961097819a05437a842b7d3bf72b0a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPOR E4F1 CEP192 ZNF710 SORL1

2.09e-0415215850652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|World / disease group, cell group and cell class (v2)

APBA2 PPFIA3 TBCCD1 ROBO1 LEF1

2.09e-041521585f944743f40ff6ed3a7a096dd53e12d3526c67c4d
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

ZBTB7C PODXL CC2D1A AFAP1L1 CHST7

2.22e-041541585212c340a096a3a9669d1aebd61c045cf1402a868
ToppCellmild_COVID-19_(asymptomatic)-CD8+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

APBA2 PPFIA3 TBCCD1 ROBO1 LEF1

2.29e-041551585e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

NES ZBTB7C PTPRD KIAA1755 FGD5

2.29e-041551585e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PODXL AFAP1L1 FGD5 PKN3 TBCD

2.29e-04155158559035d792c26d870a8b097939e97fa47859ba68c
ToppCell368C-Myeloid-Monocyte-CD16+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

CRTAC1 CEP192 RAB11FIP4 ZNF697 SORL1

2.36e-04156158525b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES PODXL PPFIA3 FGD5 CX3CL1

2.36e-041561585ff39712c7a2dc1b85c598d5105789aa291dea726
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A

USB1 APBA2 NCAPH2 ARID1A RFWD3 ZNF710 PLEKHG3 RABGAP1L ADGRE5 TBCD JHY

1.14e-07196156115020_DN
DrugCalycanthine [595-05-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A

MAP1A USB1 ARHGEF12 FBXO11 PPFIA3 RYR1 EHD2 ARVCF PLEKHG3 DGCR8

9.11e-07193156102764_UP
Drugtrichostatin A; Down 200; 0.1uM; ssMCF7; HG-U133A

AKAP8 PFAS ARID1A AXIN1 ZNF710 PER2 EIF4A1 C11orf68 CDC42EP2 DGCR8

9.11e-0719315610413_DN
DrugDelcorine; Up 200; 8.4uM; HL60; HT_HG-U133A

CACNB1 MAP1A APBA2 NCAPH2 ITIH2 CREBZF AXIN1 CDC42EP2 PRKCA LEF1

1.15e-06198156102178_UP
DrugDiflunisal [22494-42-4]; Up 200; 16uM; PC3; HG-U133A

FNBP4 NCAPH2 PPFIA3 AXIN1 ZNF710 NUDT11 ARVCF PLEKHG3 CDC42EP2 DGCR8

1.26e-06200156101908_UP
Drugpioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A

MIER2 EPOR CACNB1 MAP1A PPFIA3 RYR1 FBXO2 ARVCF JHY

7.98e-0619415697523_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; PC3; HG-U133A

EPOR CACNB1 NOL6 ARVCF PLEKHG3 CDC42EP2 PRKCA CHST7 INO80B

8.32e-061951569433_UP
DrugHesperetin [520-33-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

EPOR SETD1A AKAP8 FBXO11 GCDH PPFIA3 RABGAP1L CDC42EP2 DGCR8

8.67e-0619615691531_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

SETD1A CACNB1 NOL6 NCAPH2 ITIH2 ZNF710 PRKCA HEMK1 JHY

9.03e-0619715696143_DN
DrugPentylenetetrazole [54-95-5]; Up 200; 29uM; HL60; HG-U133A

EPOR POLG ARHGEF12 FBXO11 CRTAC1 NCAPH2 ZNF710 ARVCF PLEKHG3

9.03e-0619715691408_UP
DrugBumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A

EPOR SETD1A POLG PPFIA3 AXIN1 ZNF710 FANCE AKAP13 PLXNB1

9.03e-0619715697440_DN
DrugTiratricol, 3,3',5-triiodothyroacetic acid [51-24-1]; Up 200; 6.4uM; HL60; HG-U133A

EPOR WIPI1 POLG CRTAC1 ITIH2 AXIN1 PLEKHG3 PRKCA HEMK1

9.41e-0619815691412_UP
DrugMetixene hydrochloride [1553-34-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

DOCK1 SETD1A NCAPH2 HNRNPU EHD2 ADGRE5 DGCR8 INO80B JHY

9.41e-0619815693313_DN
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A

SETD1A MAP1A USB1 AXIN1 ZNF710 AKAP13 PLXNB1 INO80B TBCD

9.79e-0619915694297_DN
Drug2-propylpentanoic acid; Down 200; 50uM; MCF7; HG-U133A

TFEB SETD1A CACNB1 POLG ARID1A AXIN1 ZNF710 KLHL11 UBE2O

9.79e-061991569348_DN
DrugPP-IP(5

ARHGAP4 NUDT11 NUDT3 NUDT10

1.41e-05221564CID000127296
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

EXOSC10 AKAP8 POLG PFAS ARID1A ZNF710 ARVCF DGCR8

3.37e-051791568332_DN
Drugadenosine 5'-tetraphosphate

NUDT11 NUDT10

4.66e-0521562ctd:C017991
Drugdiadenosine 5',5''''-P1,P6-hexaphosphate

NUDT11 NUDT10

4.66e-0521562ctd:C070070
Drugadenosine 5'-pentaphosphate

NUDT11 NUDT10

4.66e-0521562ctd:C048567
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

NES CC2D1A NCAPH2 ZNF592 PLEKHG3 CDC42EP2 HSPB8 INO80B

4.95e-0518915686997_DN
DrugBromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A

EPOR WDR33 HNRNPU ZNF710 PLEKHG3 AKAP13 ADGRE5 HEMK1

5.95e-0519415685665_DN
DrugIodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A

ARID1A CREBZF ARVCF AKAP13 ADGRE5 STRA6 INO80B JHY

5.95e-0519415684848_DN
Drug0173570-0000 [211245-44-2]; Down 200; 1uM; MCF7; HT_HG-U133A

USB1 HNRNPU ARHGAP4 PER2 ARVCF RABGAP1L CDC42EP2 JHY

5.95e-0519415684715_DN
DrugSC 19220; Up 200; 10uM; PC3; HT_HG-U133A

SETD1A ARHGEF12 NCAPH2 PPFIA3 HNRNPU ZNF592 HEMK1 DGCR8

5.95e-0519415687065_UP
DrugIdoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

NCAPH2 PPFIA3 CREBZF ZNF710 ARHGAP4 ARVCF PLEKHG3 PLXNB1

5.95e-0519415681480_DN
Drugradicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A

USB1 PFAS NCAPH2 HNRNPU ZNF710 FANCE RABGAP1L INO80B

5.95e-0519415685216_DN
DrugS(+)-Terguride [37686-84-3]; Up 200; 11.8uM; PC3; HT_HG-U133A

SECISBP2L WDR33 POLG NCAPH2 PPFIA3 ARVCF HEMK1 LEF1

6.17e-0519515686299_UP
DrugDicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

USB1 APBA2 NCAPH2 ARVCF PRKCA ADGRE5 PLXNB1 TBCD

6.17e-0519515683941_DN
DrugBudesonide [51333-22-3]; Up 200; 9.2uM; PC3; HT_HG-U133A

CACNB1 ABCA3 USB1 WDR33 ARID1A PLEKHG3 RABGAP1L INO80B

6.17e-0519515686330_UP
DrugClorsulon [60200-06-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A

DOCK1 SETD1A CACNB1 FBXO11 ARHGAP4 PTPRS AKAP13 ADGRE5

6.39e-0519615687025_UP
Drug0179445-0000 [211246-22-9]; Down 200; 1uM; PC3; HT_HG-U133A

NOL6 LARP1 CHD3 ITIH2 AXIN1 HEMK1 DGCR8 INO80B

6.39e-0519615684292_DN
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A

SETD1A NES CHD3 PPFIA3 ARID1A CREBZF CDC42EP2 HEMK1

6.39e-0519615681511_DN
DrugCromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; PC3; HT_HG-U133A

DOCK1 EPOR POLG PPFIA3 AXIN1 FBXO2 ZNF710 AKAP13

6.39e-0519615685754_DN
DrugNaringenine [480-41-1]; Up 200; 14.6uM; PC3; HT_HG-U133A

SETD1A CACNB1 RABGAP1L ARNT2 PRKCA DGCR8 LEF1 JHY

6.39e-0519615684597_UP
DrugTocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A

MAP1A FBXO2 HNRNPU ZNF710 ARVCF PTPRS RABGAP1L JHY

6.63e-0519715687351_UP
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

POLG APBA2 NCAPH2 RABGAP1L CDC42EP2 AKAP13 INO80B JHY

6.63e-0519715686012_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

SETD1A ARHGEF12 CHD3 NCAPH2 RYR1 FBXO2 RABGAP1L AKAP13

6.63e-0519715685276_UP
DrugAmodiaquin dihydrochloride dihydrate [6398-98-7]; Up 200; 8.6uM; PC3; HT_HG-U133A

POLG ITIH2 CREBZF ARVCF ARNT2 PRKCA STRA6 JHY

6.63e-0519715685747_UP
DrugU0125; Down 200; 1uM; PC3; HG-U133A

EPOR ABCA3 NOL6 PPFIA3 AXIN1 NUDT11 ARVCF DGCR8

6.63e-051971568663_DN
DrugTicarcillin sodium [4697-14-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SECISBP2L INTS1 CHD3 NCAPH2 UBE2O PRKCA AKAP13 TBCD

6.63e-0519715687185_DN
DrugBenzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; PC3; HT_HG-U133A

TFEB EPOR ABCA3 POLG NCAPH2 FBXO2 PLEKHG3 INO80B

6.63e-0519715684022_DN
DrugDropropizine (R,S) [17692-31-8]; Down 200; 17uM; MCF7; HT_HG-U133A

SECISBP2L EPOR NES NOL6 GCDH NCAPH2 XPNPEP1 CDC42EP2

6.87e-0519815685531_DN
DrugCarbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A

EPOR WIPI1 USB1 FBXO11 ARID1A FBXO2 ZNF710 PRKCA

6.87e-0519815685399_UP
DrugAmyleine hydrochloride [532-59-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A

EPOR CHD3 NCAPH2 PPFIA3 ZNF710 ARVCF PLEKHG3 INO80B

6.87e-0519815681491_DN
DrugCefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A

SETD1A AKAP8 POLG NOL6 NCAPH2 CREBZF HNRNPU AKAP13

6.87e-0519815683259_DN
DrugRemoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; MCF7; HT_HG-U133A

KRT12 PPP1R9A APBA2 ITIH2 ZNF710 EHD2 INO80B JHY

6.87e-0519815686503_UP
DrugMeclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

EPOR SETD1A USB1 APBA2 ARID1A PRKCA DGCR8 TBCD

6.87e-0519815683405_UP
Drug(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A

USB1 APBA2 CREBZF FANCE ARVCF PTPRS PLEKHG3 STRA6

6.87e-0519815686053_DN
DrugDacarbazine [4342-03-4]; Up 200; 22uM; HL60; HG-U133A

CACNB1 POLG NOL6 CC2D1A GCDH ZNF710 PRKCA DGCR8

6.87e-0519815681762_UP
Drugalpha-estradiol; Down 200; 0.01uM; PC3; HG-U133A

EPOR POLG INTS1 ZNF629 APBA2 NCAPH2 NUDT11 TRAPPC12

6.87e-051981568702_DN
DrugFlunarizine dihydrochloride [30484-77-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A

NES WIPI1 PPFIA3 FANCE RABGAP1L ARNT2 CDC42EP2 HEMK1

6.87e-0519815687013_DN
DrugMinaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; PC3; HG-U133A

CACNB1 PPFIA3 AXIN1 FANCE NUDT11 CDC42EP2 AKAP13 ADGRE5

7.11e-0519915681888_UP
DrugLevocabastine hydrochloride [79547-78-7]; Down 200; 8.8uM; MCF7; HT_HG-U133A

EPOR NES ARHGEF12 PPFIA3 CREBZF PPP1R26 AKAP13 INO80B

7.11e-0519915687009_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; HL60; HG-U133A

USB1 APBA2 LARP1 GCDH CHD3 NCAPH2 ARHGAP4 HEMK1

7.11e-0519915681586_DN
DrugAcetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A

CACNB1 MAP1A POLG NCAPH2 ARVCF DGCR8 CHST7 PLXNB1

7.11e-0519915687461_UP
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A

NOL6 NCAPH2 CREBZF ZNF710 CDC42EP2 AKAP13 ADGRE5 PLXNB1

7.11e-0519915681509_DN
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; HL60; HT_HG-U133A

SETD1A CACNB1 MAP1A USB1 NCAPH2 CREBZF ZNF710 LEF1

7.11e-0519915682386_DN
DrugHomosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A

TFEB POLG ARHGEF12 CREBZF ARVCF HEMK1 DGCR8 PLXNB1

7.11e-0519915683879_DN
DrugTolbutamide [64-77-7]; Up 200; 14.8uM; MCF7; HT_HG-U133A

TFEB EPOR WDR33 RALYL CC2D1A ITIH2 DGCR8 LEF1

7.11e-0519915682320_UP
DrugPancuronium bromide [15500-66-0]; Up 200; 5.4uM; MCF7; HT_HG-U133A

MAP1A CC2D1A NCAPH2 FBXO2 ZNF710 PLEKHG3 RABGAP1L JHY

7.37e-0520015687329_UP
DrugButacaine [149-16-6]; Up 200; 13uM; MCF7; HT_HG-U133A

PPFIA3 ARID1A CREBZF EHD2 RABGAP1L ADGRE5 DGCR8 CHST7

7.37e-0520015686225_UP
Drug6-thioguanine; Up 200; 10uM; MCF7; HG-U133A

CACNB1 PODXL POLG NOL6 NCAPH2 PTPRD ARVCF SORL1

7.37e-052001568642_UP
DrugStrophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

USB1 FBXO11 CC2D1A CHD3 NCAPH2 TRAPPC12 PLEKHG3 HEMK1

7.37e-0520015687182_DN
Drug6-aminothymine

RRM2B TYMP

1.39e-0431562CID000065245
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

EXOSC10 LARP1 ARID1A AXIN1 ZNF710 PER2 C11orf68

2.32e-0417815671672_DN
Drugtetraphenylboron

TFEB KRT12 TYMP

2.39e-04181563CID000008934
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

AKAP8 CHD3 ARID1A NCBP3 TRAPPC12 EIF4A1 HSPB8

2.40e-0417915672105_DN
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A

EPOR SETD1A WIPI1 CHD3 ROBO1 HEMK1 STRA6

2.75e-0418315673480_UP
DrugP(1),P(5)-di(adenosine-5'-)pentaphosphate

NUDT11 NUDT10

2.77e-0441562ctd:C012275
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

FBXO11 AXIN1 ZNF710 TRAPPC12 PLEKHG3 ADGRE5 CHST7

3.34e-0418915671651_DN
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A

USB1 PPP1R9A CC2D1A CHD3 NCAPH2 CREBZF FANCE

3.56e-0419115674969_DN
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; HL60; HT_HG-U133A

SETD1A CACNB1 NCAPH2 ZNF710 RABGAP1L DGCR8 TBCD

3.56e-0419115672499_DN
DrugProguanil hydrochloride [637-32-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

EPOR NES PPFIA3 HNRNPU PLXNB1 INO80B TBCD

3.68e-0419215673505_DN
DrugSolasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

EPOR USB1 FBXO11 NCAPH2 PPFIA3 RABGAP1L STRA6

3.68e-0419215676025_DN
DrugFluspirilen [1841-19-6]; Up 200; 8.4uM; HL60; HT_HG-U133A

ARID1A ITIH2 AXIN1 ARNT2 DGCR8 STRA6 INO80B

3.79e-0419315673086_UP
Druggeldanamycin; Down 200; 1uM; MCF7; HG-U133A

FBXO11 NCAPH2 EHD2 TRAPPC12 CDC42EP2 PRKCA PLXNB1

3.79e-041931567593_DN
Drugindomethacin, USP; Up 200; 20uM; MCF7; HG-U133A

EPOR MAP1A ARID1A TYMP UBE2O DGCR8 JHY

3.79e-041931567262_UP
DrugThioguanosine [85-31-4]; Up 200; 12.6uM; HL60; HT_HG-U133A

AKAP8 WDR33 PPFIA3 ZNF710 NCBP3 DGCR8 CHST7

3.91e-0419415671264_UP
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A

NOL6 PFAS CREBZF AXIN1 HEMK1 INO80B TBCD

3.91e-0419415672485_DN
DrugNaftifine hydrochloride [65473-14-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

FBXO11 CHD3 NCAPH2 HNRNPU ZNF710 ADGRE5 JHY

3.91e-0419415677032_UP
DrugButirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A

DOCK1 EPOR FBXO11 CHD3 CREBZF PLEKHG3 HEMK1

3.91e-0419415676779_DN
DrugIsoetharine mesylate salt [7279-75-6]; Down 200; 12uM; HL60; HT_HG-U133A

CACNB1 USB1 CREBZF PRKCA CHST7 INO80B TBCD

3.91e-0419415672711_DN
DrugZardaverine [101975-10-4]; Up 200; 15uM; MCF7; HT_HG-U133A

EPOR FBXO11 NCAPH2 RYR1 FBXO2 ARVCF ADGRE5

3.91e-0419415677347_UP
DrugGlimepiride [93479-97-1]; Up 200; 8.2uM; PC3; HT_HG-U133A

TFEB CACNB1 EHD2 ARVCF RABGAP1L PRKCA STRA6

3.91e-0419415676628_UP
DrugHarmaline hydrochloride dihydrate [6027-98-1]; Up 200; 14uM; MCF7; HT_HG-U133A

CACNB1 ABCA3 NOL6 INTS1 NCAPH2 ARHGAP4 INO80B

4.03e-0419515672805_UP
DrugGlafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A

SECISBP2L POLG BAD PPFIA3 ARID1A FANCE INO80B

4.03e-0419515677018_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

LARP1 GCDH CHD3 AXIN1 TRAPPC12 CDC42EP2 INO80B

4.03e-0419515671700_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

CACNB1 NCAPH2 CREBZF PTPRS C11orf68 DGCR8 CHST7

4.03e-0419515672208_DN
DrugBetonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A

TFEB EPOR WDR33 CREBZF ARVCF HEMK1 PLXNB1

4.03e-0419515673642_UP
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A

SETD1A WIPI1 NCAPH2 ARID1A ZNF710 PRKCA DGCR8

4.03e-0419515676235_UP
Drugnovobiocin sodium, USP; Down 200; 100uM; SKMEL5; HG-U133A

POLG GCDH AXIN1 HNRNPU UBE2O ARVCF TRNAU1AP

4.03e-041951567632_DN
DrugPiretanide [55837-27-9]; Down 200; 11uM; MCF7; HT_HG-U133A

SECISBP2L USB1 PPFIA3 PLEKHG3 RABGAP1L CDC42EP2 DGCR8

4.03e-0419515676828_DN
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

TFEB EPOR AKAP8 NOL6 GCDH NCAPH2 ARHGAP4

4.03e-0419515671144_DN
DrugZimelidine dihydrochloride monohydrate [61129-30-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

EPOR AKAP8 FBXO11 CREBZF AXIN1 HNRNPU STRA6

4.16e-0419615671512_DN
DrugNiacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A

DOCK1 NCAPH2 PPFIA3 CREBZF HNRNPU STRA6 INO80B

4.16e-0419615675301_UP
DrugEburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A

MAP1A PPP1R9A INTS1 ARHGEF12 ARVCF EIF4A1 STRA6

4.16e-0419615672781_UP
Drugquercetin dihydrate; Up 200; 1uM; MCF7; HT_HG-U133A_EA

KRT12 MAP1A NCAPH2 PPFIA3 FBXO2 EHD2 RABGAP1L

4.16e-041961567917_UP
DrugUrsolic acid [77-52-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

EPOR CHD3 NCAPH2 ZNF710 PLEKHG3 CDC42EP2 SORL1

4.16e-0419615677181_DN
Drug3-nitropropionic acid; Up 200; 10uM; PC3; HT_HG-U133A

TFEB NCAPH2 CREBZF FBXO2 HNRNPU ARVCF HSPB8

4.16e-0419615676372_UP
DiseaseMITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY SYNDROME

POLG RRM2B TYMP

1.26e-0731493C0872218
Diseasetestosterone measurement

TFEB AMER1 NYAP2 MAP1A FNBP4 ZNF629 WDR81 FBXO11 CRTAC1 SSR2 ARID1A BIRC6 TRAPPC12 PRKCA LEF1 MYO16 PKN3 JHY MORN3

2.44e-05127514919EFO_0004908
Diseasemitochondrial encephalomyopathy (is_implicated_in)

POLG TYMP

2.53e-0521492DOID:890 (is_implicated_in)
DiseaseMitochondrial DNA Depletion Syndrome 1

POLG TYMP

2.53e-0521492C4551995
DiseaseMitochondrial DNA depletion syndrome 1

POLG TYMP

2.53e-0521492cv:C4551995
DiseaseVisceral myopathy familial external ophthalmoplegia

RRM2B TYMP

2.53e-0521492C1848586
DiseaseMITOCHONDRIAL DNA DEPLETION SYNDROME 1 (MNGIE TYPE)

POLG TYMP

2.53e-0521492603041
Disease5-methyluridine (ribothymidine) measurement

NCAPH2 TYMP PTPRS

4.41e-05141493EFO_0020013
Diseaseresponse to anti-tuberculosis drug, drug-induced liver injury

PTPRD ROBO1

7.57e-0531492EFO_0004228, EFO_0007918
Diseasemean corpuscular hemoglobin concentration

WIPI1 NYAP2 AKAP8 APOA5 PAGE2 LARP1 PFAS GCDH XPNPEP1 TYMP AXIN1 NLRP6 CC2D2A AKAP13 DOT1L MYO16

1.55e-04110514916EFO_0004528
DiseaseProgressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1

POLG RRM2B

2.51e-0451492C1834846
Diseaseferritin measurement

ZBTB7C FNBP4 AXIN1 PTPRD MYO16

3.53e-041191495EFO_0004459
DiseaseMalignant neoplasm of breast

EPOR ABCA3 AKAP8 RALYL ARID1A PTPRD PER2 TRAPPC12 NLRC5 ROBO1 BOD1L1 FGD5 LEF1 PLXNB1 SORL1

3.67e-04107414915C0006142
Diseaseintermittent claudication (biomarker_via_orthology)

BAD BAK1

3.75e-0461492DOID:3669 (biomarker_via_orthology)
Diseaseglaucoma (biomarker_via_orthology)

EPOR BAD HDAC1

3.77e-04281493DOID:1686 (biomarker_via_orthology)
DiseaseBilateral Wilms Tumor

AMER1 ARID1A DGCR8

4.19e-04291493C2930471
DiseaseNAD-dependent protein deacetylase sirtuin-2 measurement

ITIH2 PRKCA

5.23e-0471492EFO_0008241
Diseasehypothyroidism (biomarker_via_orthology)

PLOD3 MAP1A APOA5 BAD

7.33e-04801494DOID:1459 (biomarker_via_orthology)
DiseaseNephroblastoma

AMER1 ARID1A DGCR8

7.97e-04361493C0027708
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

NYAP2 MAP1A APOA5 CRTAC1 ARID1A NLRC5

9.97e-042241496EFO_0004574, EFO_0008317
Diseasepolymyositis (is_marker_for)

ROBO1 CX3CL1

1.35e-03111492DOID:0080745 (is_marker_for)
Diseaselipid measurement, high density lipoprotein cholesterol measurement

WIPI1 NYAP2 MAP1A APOA5 ARID1A NUDT3 NLRC5

1.49e-033301497EFO_0004529, EFO_0004612
Diseaseplatelet component distribution width

NYAP2 APOA5 ZNF629 CRTAC1 ZNF710 PWWP2A UBE2O ARVCF PLEKHG3 AKAP13 ADGRE5

1.62e-0375514911EFO_0007984
Diseasecreatinine measurement

TFEB WIPI1 NYAP2 ARID1A BIRC6 RYR1 RFWD3 NUDT3 ZNF592 KIAA1755 BSN UNC80 SORL1

1.66e-0399514913EFO_0004518
Diseasebrain ischemia (biomarker_via_orthology)

EPOR NES BAD PRKCA

1.81e-031021494DOID:2316 (biomarker_via_orthology)
Diseasebody weight

SECISBP2L DOCK1 ZBTB7C RALYL BAD ARHGEF12 CRTAC1 E4F1 CEP192 PPFIA3 AXIN1 NUDT3 RABGAP1L HEMK1 DOT1L

1.85e-03126114915EFO_0004338
Diseaselipoprotein measurement

DOCK1 NYAP2 ARID1A NLRC5

2.01e-031051494EFO_0004732
DiseaseImpaired cognition

EIF2B5 SORL1

2.21e-03141492C0338656
Diseasereticulocyte measurement

WIPI1 NYAP2 FLVCR1 LARP1 PFAS GCDH USP37 BIRC6 KLHL11 UBE2O NUDT3 AKAP13 BSN

2.71e-03105314913EFO_0010700
Diseasealcohol dependence measurement

PODXL FGD5 MYO16

2.73e-03551493EFO_0007835
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

WIPI1 NYAP2 APOA5 CRTAC1 BIRC6 NLRC5

2.86e-032761496EFO_0004612, EFO_0020943
DiseaseDiGeorge Syndrome

ARVCF DGCR8

2.90e-03161492C0012236
DiseaseCONOTRUNCAL ANOMALY FACE SYNDROME

ARVCF DGCR8

2.90e-03161492C0795907
DiseaseShprintzen syndrome

ARVCF DGCR8

2.90e-03161492C0220704
Diseasemyeloid white cell count

ARHGEF12 SSR2 UBE2O ARVCF RABGAP1L NLRC5 KIAA1755 ADGRE5 DOT1L PLXNB1 PKN3 SORL1

2.93e-0393714912EFO_0007988
Diseasefree androgen index

TFEB NYAP2 FNBP4 ARID1A PRKCA PKN3 JHY

3.00e-033741497EFO_0007005
DiseaseColorectal Carcinoma

CACNB1 ABCA3 ARID1A TYMP ZNHIT6 PTPRD PTPRS LEF1 DNAH8 SORL1

3.09e-0370214910C0009402
Diseasefree cholesterol in medium HDL measurement

NYAP2 ARID1A NLRC5

3.18e-03581493EFO_0022267
DiseaseMuscle hypotonia

RRM2B INTS1

3.28e-03171492C0026827
Diseasedermatomyositis (is_marker_for)

ROBO1 CX3CL1

3.28e-03171492DOID:10223 (is_marker_for)
Diseasecholesterol in medium HDL measurement

NYAP2 ARID1A NLRC5

3.34e-03591493EFO_0021903
Diseaseinsulin resistance

DOCK1 NYAP2 PTPRD

3.34e-03591493EFO_0002614
Diseasetriglycerides to total lipids in large HDL percentage

NYAP2 ARID1A NLRC5

3.50e-03601493EFO_0022330
Diseasephospholipids in HDL measurement

NYAP2 ARID1A NLRC5

3.67e-03611493EFO_0022293
Diseasemean arterial pressure

NYAP2 PODXL ARHGEF12 IKZF4 PTPRD PRKCA ROBO1 FGD5

3.96e-034991498EFO_0006340
Diseasetotal lipids in HDL measurement

NYAP2 ARID1A NLRC5

4.02e-03631493EFO_0022307
Diseasesexual dimorphism measurement

NYAP2 APOA5 PODXL ARID1A ZNF710 FANCE NUDT3 ZNF592 C11orf68 NLRC5 RAB11FIP4 DOT1L BSN

4.10e-03110614913EFO_0021796
Diseaserenal cell carcinoma (is_marker_for)

BAD BAK1 PFAS TYMP

4.10e-031281494DOID:4450 (is_marker_for)
DiseaseProstatic Neoplasms

PODXL BAD CHD3 SSR2 ARID1A ROBO1 AKAP13 CX3CL1 GOLGA4

4.19e-036161499C0033578
DiseaseMalignant neoplasm of prostate

PODXL BAD CHD3 SSR2 ARID1A ROBO1 AKAP13 CX3CL1 GOLGA4

4.19e-036161499C0376358
Diseasehepatocellular carcinoma (is_marker_for)

PLOD3 FBXO11 PFAS ARID1A AXIN1 NLRC5

4.36e-033011496DOID:684 (is_marker_for)
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

WIPI1 NYAP2 APOA5 ARID1A BIRC6 NLRC5

4.50e-033031496EFO_0004612, EFO_0020945
Diseaseexercise test

PTPRD PRKCA

4.53e-03201492EFO_0004328
Diseasetotal lipids in very large HDL measurement

WIPI1 NYAP2 NLRC5

4.58e-03661493EFO_0022312
Diseasevery low density lipoprotein particle size measurement

NYAP2 APOA5 CRTAC1 ARID1A

4.70e-031331494EFO_0008594

Protein segments in the cluster

PeptideGeneStartEntry
ADPAQGVAPEMGLAD

C1orf167

1376

Q5SNV9
PEPPGAMAASEDEEE

CHMP3

191

Q9Y3E7
DDGGELADERPAFPM

ARVCF

306

O00192
PEDEALTPGDECMDG

BIRC6

4041

Q9NR09
GDSCVDMETDPSEGP

CACNB1

516

Q02641
GPPDPDDLAQEMEDV

AAMP

36

Q13685
YPAGTEDDEGMGEEP

BAD

76

Q92934
EDDEGMGEEPSPFRG

BAD

81

Q92934
EVSAGQMPGPAEAEL

HTR3E

386

A5X5Y0
PVGAEAGPEDMEDGD

SH3BP5L

291

Q7L8J4
EQEAEGVAAPADPEM

BAK1

46

Q16611
VDPEMEGDDNLGGED

AKAP8

551

O43823
PFVERGPDEAMEDGE

EHD2

421

Q9NZN4
DELMEAPGDVEALAP

ADGRE5

306

P48960
MGAEGRESESEPADP

AKAP13

1516

Q12802
GAMDPSDGIGALIEE

ABCA3

876

Q99758
QGGGEEMALPDDDDE

AMER1

366

Q5JTC6
TEEGAGPDPQMLSEE

APOA5

266

Q6Q788
DLGPSGPSEENFDME

CUEDC2

41

Q9H467
SEDMELPLEGYVPEG

APBA2

31

Q99767
GPADAPMDSGAEEEK

DOT1L

366

Q8TEK3
AELEFPLDEPDSMGA

DGCR8

386

Q8WYQ5
EAEGPAGDSMDAEGP

CLIC6

271

Q96NY7
MLPAVGSVDEEEDPA

CBWD5

1

Q5RIA9
PTMEPEGGLDDSGEH

ARHGEF12

1366

Q9NZN5
PAGMTIPEEDADVGQ

ARNT2

291

Q9HBZ2
EGVIEPDTDAPQEMG

ST13P5

86

Q8NFI4
EGVIEPDTDAPQEMG

ST13

86

P50502
GMEPEEEPGGAAVRE

NUDT10

51

Q8NFP7
EEPAEGGPDADGEEM

RALYL

256

Q86SE5
GPSEVMAGPAEEAGA

TP53I13

21

Q8NBR0
EPLLPSASMDEEEGD

RFWD3

271

Q6PCD5
EDEEEAMTLAPPEGP

RAB11FIP4

136

Q86YS3
GGGDPELCATDEMIP

LEF1

11

Q9UJU2
PAPMEGGEEEEELLG

ARID1A

1756

O14497
GPEEALSPGEARDMA

PLOD3

361

O60568
GDQGPPEEAEDRFSM

PODXL

446

O00592
LEDFRVDPPMGEEGN

LARP1

1021

Q6PKG0
AAEQESGELDPGMEP

MAP1A

2281

P78559
EDLGLMGAQEPTGEE

MAGEA9

21

P43362
GNGMEPDSLDEEESP

JHY

66

Q6NUN7
VGGPGEVSVEMDAAP

KRT12

276

Q99456
PPMEEDVGDTDVLQG

INTS1

1011

Q8N201
ENEAGDERMLADAPP

ITIH2

631

P19823
MQAIPEDAIPEESGD

HDAC1

381

Q13547
MDDDAAPRVEGVPVA

KAAG1

1

Q9UBP8
PPGDEDDSEPVYIEM

MYO16

1401

Q9Y6X6
PPSDMDSEAEDLVGN

GOLGA4

116

Q13439
ASIEEFEKADPPGGM

KIAA1755

741

Q5JYT7
PDEHQDMDADPGGPE

FLYWCH1

406

Q4VC44
PAALDGGEEGMDIIT

HEMK1

261

Q9Y5R4
PGELDGSDEEEAEGM

PPFIA3

571

O75145
LDDGFGMDPFPDDLT

HSPB8

31

Q9UJY1
EEPAGALDLTGMRPE

BSN

1881

Q9UPA5
MLPAVGSADEEEDPA

CBWD2

1

Q8IUF1
MLPAVGSADEEEDPA

CBWD1

1

Q9BRT8
EEPDSRGGSPQMDDI

EIF2B5

536

Q13144
MDGDGDPESVGQPEE

FBXO2

1

Q9UK22
DNGPDGMEPEGVIES

EIF4A1

11

P60842
PELEMVEDAASGPES

PER2

686

O15055
PGERTPMLEDVDEGG

PLXNB1

1866

O43157
GGMEPEEEPSVAAVR

NUDT3

51

O95989
EEEEIGSPEPMAAPA

KIF22

406

Q14807
EMPEPTGDEPEDSVF

DNAH8

2741

Q96JB1
EGSGPDRPTEDMGQD

FGD5

231

Q6ZNL6
DMGQDAEDTSEEPPE

FGD5

241

Q6ZNL6
ALDDEEAGGRPAMEP

HNRNPU

41

Q00839
GAAGAADSGPMEEEE

HNRNPU

111

Q00839
RGATGEPEVMEPALE

NOL6

11

Q9H6R4
EGAGAPGDPMDQEDL

POLG

516

P54098
GVDRGEPEPMEVEEG

NCBP3

31

Q53F19
PPGMAGVENEDEAEL

NES

966

P48681
ECEDGPDGQEMDPPN

GAGE2D;

86

Q9UEU5
EDEPGDGPDVREGIM

PAGE2B

81

Q5JRK9
ECEDGPDGQEMDPPN

GAGE2A

86

Q6NT46
GMEPEEEPGGAAVRE

NUDT11

51

Q96G61
MGSPAGDPEEEEPVY

NYAP2

231

Q9P242
FDGLDEALQPMGPDG

NLRC5

306

Q86WI3
GGPMSPQDDEAEEES

RABGAP1L

476

Q5R372
SGAMEAPEPGEALEL

INO80B

11

Q9C086
GAEDLTPEDDMPVGR

PTPRS

281

Q13332
GLMDPVDPEDSVDLG

PASD1

336

Q8IV76
EGDPSVTPAEEMGDT

BOD1L1

2276

Q8NFC6
DGEMVLPGFPDADSF

EXOSC10

21

Q01780
AMEASGGDPGPEAED

KLHL11

56

Q9NVR0
PGTMVEGPEEDGTFD

CDC42EP2

66

O14613
EEEEPPAQGGGKEMD

CC2D2A

226

Q9P2K1
ELNGMTGADVADVPP

DOCK1

1786

Q14185
MDGVEVPEENVLPGA

GCDH

266

Q92947
VPADMVAEESGPGAQ

FBXO11

81

Q86XK2
DMDEPPPLDYGSGED

CHD3

586

Q12873
QDMDEDDGRDAAPPG

AXIN1

251

O15169
EEGSGQRPEEIPMDL

ZNHIT6

61

Q9NWK9
MLPAVGSVDEEEDPA

CBWD3

1

Q5JTY5
MLPAVGSVDEEEDPA

CBWD6

1

Q4V339
DLSPDGLMIPEDGAN

CC2D1A

26

Q6P1N0
MARPDDEEGAAVAPG

FLVCR1

1

Q9Y5Y0
FDLMGLSPDAPEDEA

LYPLA2

76

O95372
LQMETAGPEEEPAGA

CEP192

121

Q8TEP8
TMQAVEPGTDDEGPL

EPOR

341

P19235
GNVGPDALIEMDPEA

CRTAC1

201

Q9NQ79
EAELGDGEMAEAPGS

E4F1

151

Q66K89
MATPDAGLPGAEGVE

FANCE

1

Q9HB96
REPPEGSLLDVDMDG

FAM83H

76

Q6ZRV2
GDDGLPAPMEAEAYE

FAM83H

596

Q6ZRV2
YKVSDSPPGEDDMEG

RYR1

4581

P21817
SPPGEDDMEGSAAGD

RYR1

4586

P21817
TESPMGALQPDEAEE

PRRT3

381

Q5FWE3
GQPGDEIRDLEMVPD

IKZF4

286

Q9H2S9
SAAPEEAMGPAEEPE

NLRP6

156

P59044
LEEEAGEGGQDMPEA

DIPK1C

131

Q0P6D2
ESEGGDVAPNLPDMT

MIER2

106

Q8N344
GTMIDFGRDEAPEPT

MORN3

196

Q6PF18
EDEPGDGPDVREGIM

PAGE2

81

Q7Z2X7
EMLVGECPFPGDTEE

PKN3

751

Q6P5Z2
LGAEDLTPEDDMPIG

PTPRD

271

P23468
DMDEAEEGYPPATGP

MAP3K15

1151

Q6ZN16
AERDVPDPQEGVGME

NUTM2E

656

B1AL46
SVGTEEMPEDGEPDA

SYVN1

586

Q86TM6
GEGGAGEAEPEMEPI

PWWP2A

16

Q96N64
DEDAPMITGFSDDVP

SORL1

2196

Q92673
VGDDALEDPMPQLDV

TRNAU1AP

236

Q9NX07
PSEEGPGEALMLGAE

TFEB

351

P19484
MAAAEEEDGGPEGPN

RNF5

1

Q99942
EMEDEGSEEPPAPGT

FNBP4

741

Q8N3X1
MLAGQPPFDGEDEDE

PRKCA

531

P17252
KPVGPEDMGATADFE

RNF113B

101

Q8IZP6
EEMGGAAQEPESLLP

PLEKHG3

581

A1L390
ECEDGPDGQEMDPPN

GAGE2B

86

Q13066
GLSMDGEEAPAPEDV

SAMD11

526

Q96NU1
EEAEAPEVLEPGMDS

SECISBP2L

1051

Q93073
DPMGEEETTDFGPLV

PPP1R26

106

Q5T8A7
SPPEVEGAMAVNDGL

SYCE1L

181

A8MT33
DGAVVSPDLGDMSPE

HERC2P3

1071

Q9BVR0
DDMEISDDDRGGSPP

SETD1A

581

O15047
LGADNEPELEAEMPA

ARHGAP4

726

P98171
APQDSLRPGEEDEGM

STRA6

601

Q9BX79
MPEDDGEPSKGASPE

AFAP1L1

86

Q8TED9
GDAEQPREGETPLEM

CHST7

466

Q9NS84
PREGETPLEMDADGA

CHST7

471

Q9NS84
MPLGGGEDEDAEEAV

NCAPH2

251

Q6IBW4
RMEPGEELEEEGSPG

C11orf68

41

Q9H3H3
MGDPERPEAAGLDQD

RRM2B

1

Q7LG56
APGDSGERSEGEAME

ZNF511

191

Q8NB15
DDSFPPEDFGIVSGM

SSR2

61

P43308
EPEGEAMDAELAVAP

USP22

6

Q9UPT9
DEPLEAGMIVTDEPG

XPNPEP1

511

Q9NQW7
EPSIEPEGMSNAGAE

UNC80

1436

Q8N2C7
MEDAGGGEETPAPEA

TRAPPC12

1

Q8WVT3
GGDPNEDAAEMGPDS

PFAS

1171

O15067
GSAIAEAPSEMPGDE

ZNF592

411

Q92610
EAPSEMPGDEVPVEE

ZNF592

416

Q92610
PEEGSGEEVPMETRE

ZNF592

1201

Q92610
AGEEMTPPAGLAEEL

TRIL

436

Q7L0X0
PDGSASPVEMQDEGA

UBE2O

436

Q9C0C9
GGVAVRAPSPEEMEE

CREBZF

71

Q9NS37
DLGPELSGAAMGEPE

ZNF710

46

Q8N1W2
MDDEGDDDPVPLPNV

SKP1

36

P63208
GPLVSDMDTDAPEEE

ROBO1

1316

Q9Y6N7
NMFPGTEEGPEDDST

USB1

51

Q9BQ65
EGDPEEREMGSNPHD

ZNF697

31

Q5TEC3
PDTGFAEDDIQEMPE

USP37

736

Q86T82
IMEPGGDGGEEDDKE

ZBTB7C

126

A1YPR0
ELGTEMLGDLEEEGP

ZNF212

191

Q9UDV6
AMFSAPVDEKPGGEE

TSPYL6

156

Q8N831
PVDEKPGGEEMDVAE

TSPYL6

161

Q8N831
MALSDEPAAGGPEEE

TBCD

1

Q9BTW9
IPFEMEGDTTEIPGG

TBCCD1

471

Q9NVR7
MEAEAADAPPGGVES

WIPI1

1

Q5MNZ9
PGMSEDGVEYDDLEP

WDR33

421

Q9C0J8
GEEIIMGDPAQSPES

ZNF629

41

Q9UEG4
EVEEALLCMDGAGPP

TYMP

286

P19971
PGSCAFGEEIPMDGE

WDR81

1041

Q562E7
TAGPEEAPMREAEAG

nan

6

Q6ZQT7
PAAGGMDESVVLEPE

CX3CL1

116

P78423
DEVGPVLPGSDMAIE

PPP1R9A

641

Q9ULJ8