Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2

3.46e-0512152GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2

4.77e-0514152GO:0097493
GeneOntologyMolecularFunctionextracellular matrix structural constituent

SSPOP FBN1 FBN2

3.44e-04188153GO:0005201
GeneOntologyMolecularFunctionhormone activity

FBN1 FBN2

4.50e-03135152GO:0005179
GeneOntologyMolecularFunctionintegrin binding

ADAM22 FBN1

7.44e-03175152GO:0005178
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

2.56e-064142GO:0035583
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

1.20e-058142GO:0071694
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

2.34e-0511142GO:0035581
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

3.32e-0513142GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

3.32e-0513142GO:1900116
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

3.73e-0513152GO:0001527
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

2.31e-06352HP:0012772
HumanPhenoCrumpled ear

FBN1 FBN2

1.15e-05652HP:0009901
HumanPhenoMitral regurgitation

AKT3 FBN1 FBN2

3.07e-0416353HP:0001653
HumanPhenoAbnormal mitral valve physiology

AKT3 FBN1 FBN2

4.12e-0418053HP:0031481
HumanPhenoAtrioventricular valve regurgitation

AKT3 FBN1 FBN2

5.30e-0419653HP:0034376
HumanPhenoScaphocephaly

FBN1 FBN2

5.92e-044052HP:0030799
HumanPhenoDisproportionate tall stature

FBN1 FBN2

6.23e-044152HP:0001519
HumanPhenoAbnormal helix morphology

ALOXE3 FBN1 FBN2

6.68e-0421253HP:0011039
HumanPhenoLens dislocation

FBN1 FBN2

6.85e-044352HP:0000665
HumanPhenoEctopia lentis

FBN1 FBN2

6.85e-044352HP:0001083
HumanPhenoAbnormal atrioventricular valve physiology

AKT3 FBN1 FBN2

6.96e-0421553HP:0031650
HumanPhenoAbnormal elasticity of skin

ALOXE3 AKT3 FBN1

9.39e-0423853HP:0010647
HumanPhenoMetatarsus adductus

FBN1 FBN2

9.64e-045152HP:0001840
HumanPhenoAbnormal mitral valve morphology

AKT3 FBN1 FBN2

1.18e-0325753HP:0001633
HumanPhenoLimited elbow extension

FBN1 FBN2

1.33e-036052HP:0001377
HumanPhenoLack of skin elasticity

ALOXE3 FBN1

1.38e-036152HP:0100679
DomainFBN

FBN1 FBN2

1.56e-063142IPR011398
DomainTB

FBN1 FBN2

1.09e-057142PF00683
Domain-

FBN1 FBN2

1.46e-0581423.90.290.10
DomainTB

FBN1 FBN2

1.87e-059142PS51364
DomainTB_dom

FBN1 FBN2

1.87e-059142IPR017878
DomainEGF_3

SSPOP ADAM22 FBN1 FBN2

2.21e-05235144PS50026
DomainEGF_1

SSPOP ADAM22 FBN1 FBN2

3.05e-05255144PS00022
DomainEGF_2

SSPOP ADAM22 FBN1 FBN2

3.55e-05265144PS01186
DomaincEGF

FBN1 FBN2

1.68e-0426142IPR026823
DomaincEGF

FBN1 FBN2

1.68e-0426142PF12662
DomainEGF

ADAM22 FBN1 FBN2

6.46e-04235143SM00181
DomainEGF-like_dom

ADAM22 FBN1 FBN2

7.64e-04249143IPR000742
DomainEGF-like_CS

ADAM22 FBN1 FBN2

8.76e-04261143IPR013032
DomainEGF_CA

FBN1 FBN2

1.84e-0386142PF07645
DomainEGF_Ca-bd_CS

FBN1 FBN2

2.33e-0397142IPR018097
DomainEGF_CA

FBN1 FBN2

2.43e-0399142PS01187
DomainASX_HYDROXYL

FBN1 FBN2

2.48e-03100142PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 FBN2

2.78e-03106142IPR000152
DomainEGF_CA

FBN1 FBN2

3.66e-03122142SM00179
DomainEGF-like_Ca-bd_dom

FBN1 FBN2

3.78e-03124142IPR001881
DomainGrowth_fac_rcpt_

FBN1 FBN2

5.91e-03156142IPR009030
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

1.74e-07215212399449
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

1.74e-07215221851253
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

1.74e-07215223133647
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

1.74e-07215212429739
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

1.74e-0721528791520
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

1.74e-07215224833718
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

1.74e-07215230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

1.74e-07215221440062
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

1.74e-0721528120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

1.74e-07215235419902
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

1.74e-07215215131124
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

1.74e-0721528307578
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

1.74e-07215216407178
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

1.74e-07215210504303
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

1.74e-0721521852206
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

1.74e-07215210359653
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

1.74e-0721527744963
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

1.74e-07215224265020
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

1.74e-07215212524050
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

1.74e-07215220529844
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

1.74e-07215225524144
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

1.74e-07215226408953
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

1.74e-07215220404337
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

1.74e-07215218006876
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

FBN1 FBN2

5.21e-07315210825173
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

FBN1 FBN2

5.21e-07315230201140
Pubmed

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

FBN1 FBN2

5.21e-07315220855508
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2

1.04e-06415212429738
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2

1.04e-06415216835936
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

FBN1 FBN2

1.04e-06415225406291
Pubmed

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

FBN1 FBN2

1.04e-06415220729550
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2

1.04e-06415225034023
Pubmed

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

FBN1 FBN2

1.73e-06515226601954
Pubmed

Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.

FBN1 FBN2

1.73e-06515212590922
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBN1 FBN2

1.73e-06515217255108
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

FBN1 FBN2

1.73e-06515223493297
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 FBN2

1.73e-06515234411563
Pubmed

Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.

FBN1 FBN2

2.60e-0661527873879
Pubmed

Regulation of limb patterning by extracellular microfibrils.

FBN1 FBN2

3.64e-06715211470817
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP FBN1 FBN2

3.64e-067115333541421
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN1 FBN2

4.85e-06815223055981
Pubmed

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.

FBN1 FBN2

4.85e-06815231201465
Pubmed

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

FBN1 FBN2

4.85e-06815218339631
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 FBN2

6.24e-06915212122015
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FBN2

6.24e-06915238844137
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

FBN1 FBN2

7.80e-061015230738849
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

FBN1 FBN2

1.14e-051215226405179
Pubmed

A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.

FBN1 FBN2

1.14e-051215236779913
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

FBN1 FBN2

2.65e-051815239040056
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FBN1 FBN2

2.65e-051815235503090
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

SSPOP FBN1 FBN2

5.45e-0517515328071719
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 FBN2

5.61e-052615234189436
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

UBR5 FBN1 FBN2

6.33e-0518415332908313
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

FBN1 FBN2

7.50e-053015232882513
Pubmed

Heritable Thoracic Aortic Disease Overview

FBN1 FBN2

7.50e-053015220301299
Pubmed

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

FBN1 FBN2

8.02e-053115225762570
Pubmed

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.

FBN1 FBN2

1.08e-043615235167946
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

FBN1 FBN2

1.15e-043715234323105
Pubmed

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.

FBN1 FBN2

1.34e-044015230578393
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

GRM3 UBR5 ADAM22

1.58e-0425115327507650
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

FBN1 FBN2

2.10e-045015223658023
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GRM3 UBR5 ADAM22

2.21e-0428115328706196
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

FBN1 FBN2

2.27e-045215230389913
Pubmed

Regulation of error-prone translesion synthesis by Spartan/C1orf124.

DNAJC7 UBR5

2.93e-045915223254330
InteractionMFAP2 interactions

FBN1 FBN2

2.53e-0512132int:MFAP2
InteractionZDHHC15 interactions

SSPOP FBN1 FBN2

6.37e-05125133int:ZDHHC15
InteractionNTN5 interactions

FBN1 FBN2

1.05e-0424132int:NTN5
InteractionABHD15 interactions

DNAJC7 AKT3

1.34e-0427132int:ABHD15
InteractionELN interactions

FBN1 FBN2

1.54e-0429132int:ELN
CytobandEnsembl 112 genes in cytogenetic band chr7q21

GRM3 ADAM22

1.52e-03178152chr7q21
CoexpressionBANDRES_RESPONSE_TO_CARMUSTIN_WITHOUT_MGMT_48HR_DN

AQP8 FBN1

1.50e-0432152M9066
CoexpressionNABA_ECM_GLYCOPROTEINS

SSPOP FBN1 FBN2

1.62e-04191153MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

SSPOP FBN1 FBN2

1.75e-04196153M3008
CoexpressionGSE27786_LSK_VS_LIN_NEG_CELL_UP

GPATCH2 ADAM22 POLR1H

1.86e-04200153M4739
CoexpressionGSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP

BOC AKT3 FBN1

1.86e-04200153M9553
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

GRM3 BOC ADAM22 FBN1 FBN2

8.03e-07288145gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

BOC FBN1 FBN2

6.43e-05122143gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

GRM3 BOC ADAM22 FBN1 FBN2

1.07e-04791145gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

BOC FBN1 FBN2

1.10e-04146143gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500

BOC FBN2

2.24e-0434142gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_500
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

BOC AKT3 ADAM22 FBN1 FBN2

6.08e-041148145facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

BOC FBN1 FBN2

6.32e-04265143gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2 KCNA7

1.05e-051301537d4319aae42acc914757796877b8f0d874acbec4
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ADAM22 FBN1 FBN2

2.81e-05181153bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BOC FBN1 FBN2

3.00e-051851537dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM3 FBN1 FBN2

3.00e-05185153785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM3 FBN1 FBN2

3.00e-0518515397a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BOC FBN1 FBN2

3.05e-05186153c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM3 FBN1 FBN2

3.05e-0518615394d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BOC FBN1 FBN2

3.05e-051861534d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BOC FBN1 FBN2

3.10e-051871535258674d0346e5c51a4b965efcdc1790c970845d
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

BOC FBN1 FBN2

3.15e-051881537b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

BOC AKT3 FBN1

3.15e-05188153fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC FBN1 FBN2

3.25e-05190153947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC FBN1 FBN2

3.30e-051911534b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC FBN1 FBN2

3.30e-05191153db4943dd19207663fb9e27f8940fa4b06a933625
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC FBN1 FBN2

3.30e-0519115375d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC FBN1 FBN2

3.35e-051921538937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC FBN1 FBN2

3.35e-05192153ac1477433704573f95111eee6263b93668d2845e
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC FBN1 FBN2

3.35e-05192153e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

BOC AKT3 FBN1

3.51e-05195153f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC AKT3 FBN1

3.51e-05195153f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

BOC FBN1 FBN2

3.56e-05196153eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC AKT3 FBN1

3.62e-0519715344673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

BOC FBN1 FBN2

3.62e-051971539a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AKT3 FBN1 FBN2

3.67e-051981537a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC FBN1 FBN2

3.73e-0519915330ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCellTracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC AKT3 FBN1

3.79e-05200153f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCellTracheal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC AKT3 FBN1

3.79e-05200153b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell15-Airway|15 / Age, Tissue, Lineage and Cell class

BOC FBN1 FBN2

3.79e-05200153ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

8.23e-04128152076ba9de63b9a4b5a2f7e7924b9a86e8eafce91f
ToppCellMS-CD4-CD8_2|MS / Condition, Cell_class and T cell subcluster

GRM3 ADAM22

1.11e-0314915208fb6be5599c5988890c851ce5ac6781c319948e
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

ADAM22 FBN2

1.11e-03149152e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ALOXE3 AQP8

1.16e-031521529391b46a441cf031665df1d142e3f65e98675eeb
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM3 BOC

1.23e-031571525aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM3 BOC

1.23e-03157152921805932f7974d37aed547861d555b07f30aba6
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC FBN1

1.23e-03157152f147e24f2ece82e1c54750868954d09b3c461804
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GRM3 KCNA7

1.25e-03158152c77737d8c444fc35f998a7644d69c9b508574626
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC FBN1

1.25e-03158152e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM3 BOC

1.28e-03160152d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM22 POLR1H

1.30e-03161152176a4a72bb4892932da3c834d1fea5e211847f92
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

BOC FBN1

1.31e-03162152e17632778a57c71d6005d3abca3a0443a92040e7
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALOXE3 AQP8

1.31e-03162152b877b232f0a879a9058d81ad4730e7846484b7c3
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALOXE3 AQP8

1.31e-031621527384a4dd38ed68ca02a72df6deff4d34c9694ce1
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

BOC FBN1

1.31e-03162152ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALOXE3 ADAM22

1.33e-03163152132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKT3 POLR1H

1.33e-03163152a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellfacs-Skin-nan-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC AKT3

1.34e-031641527a65c7a6dbe5fb9067f83efafbb7ec8206d79325
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN1

1.38e-031661529d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC AKT3

1.38e-0316615294636dbc039f794c735960c3425e00bdd5523602
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

FBN2 KCNA7

1.39e-03167152dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM3 BOC

1.39e-03167152f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

BOC FBN1

1.39e-03167152d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

FBN2 KCNA7

1.39e-0316715282739226347d74897be000f429b73543a031af96
ToppCellTuft-tuft-1|World / Class top

ALOXE3 KCNA7

1.41e-031681528ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 FBN2

1.43e-03169152c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

BOC FBN1

1.43e-03169152e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN2 KCNA7

1.44e-03170152ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GRM3 BOC

1.44e-0317015267415b098e8ba815b501e557192a9f2b10ee995a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AKT3 ADAM22

1.44e-0317015232917888c3f1d54302675c1d4de1fd3b7c79af5f
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BOC FBN1

1.46e-0317115215cb4670ff4234ac46aea8a5911138d6913c4482
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BOC FBN1

1.48e-03172152e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSPOP KCNA7

1.51e-031741525d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.51e-0317415246bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SSPOP KCNA7

1.51e-03174152f1510b0f7771936adf29ae3572feab55db31832b
ToppCellwk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BOC FBN2

1.53e-03175152a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.53e-03175152284fdc7a9d303636a637041846850d19d114861a
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP FBN1

1.55e-031761523766e0533b103ec92ac75eba3df02e287efc53fa
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BOC FBN1

1.55e-03176152510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.55e-03176152327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP FBN1

1.55e-03176152aa1bada2175d8370fc71939a607407155259d195
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

ALOXE3 AKT3

1.58e-0317815251c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC FBN1

1.58e-03178152a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

BOC FBN1

1.58e-03178152371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellIIH-matDC-|IIH / Condition, Cell_class and T cell subcluster

BOC FBN1

1.60e-0317915246074b2781ed79e2979428b3ec81504621d3903c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.60e-0317915255bc69f107fc710db7617c428575792adfdbbcc1
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPATCH2 DNAJC7

1.60e-0317915269c74b2ff43b43653005807654953daf21f932ec
ToppCellIIH-matDC|IIH / Condition, Cell_class and T cell subcluster

BOC FBN1

1.60e-031791525999c85ce3bab5309ff1ed154be7e32b037750b1
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

AKT3 FBN1

1.60e-03179152dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN1

1.62e-0318015232c6a3886428d82fb4355d987c6d2645f333447b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN1

1.62e-03180152c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FBN1 FBN2

1.63e-031811529b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellwk_15-18-Mesenchymal-Chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BOC FBN2

1.63e-031811528950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

UBR5 AKT3

1.63e-03181152f2315414e714ac86211546a935660c4be6e85f1b
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BOC FBN2

1.65e-0318215203a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC FBN1

1.65e-031821523dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SSPOP FBN2

1.65e-0318215252274af3136d4fd4a495f5882618444661421f0f
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SSPOP FBN2

1.65e-03182152dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.65e-031821525e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKT3 ADAM22

1.67e-03183152b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.67e-0318315283592c332b1e82673f993d37c7f480befdc3dcda
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BOC FBN2

1.67e-0318315292fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BOC FBN1

1.67e-03183152351d575339038bd4a66f408da518c567444208e8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP FBN2

1.69e-03184152ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BOC FBN1

1.69e-0318415201257e5c12e38b849fd3d9496c43ded666249ba5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP FBN2

1.69e-031841522cbed6462fea2622871bb7e49b0df3d984239281
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC FBN1

1.69e-031841524d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SSPOP FBN2

1.69e-031841522b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

BOC FBN1

1.69e-031841522b7e6f91e11c228f0521e099886867d9e998e78d
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FBN2

1.70e-0318515201bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC FBN2

1.70e-031851528ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BOC FBN1

1.70e-03185152c85bba1210f1d389add3e40be9b96abac40cf8c1
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

ALOXE3 AKT3 FBN1 FBN2

6.61e-061951544746_UP
DrugBetonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT_HG-U133A

ALOXE3 AKT3 ADAM22 FBN2

6.75e-061961544767_UP
DrugVpgvg

BOC FBN1

8.49e-067152CID006452594
DrugAC1Q3ZOL

GRM3 BOC FBN1 KCNA7

1.99e-05258154CID000002376
Drugracemates

GRM3 BOC

6.16e-0518152CID000472252
Drugpivalate

BOC UBR5

7.64e-0520152CID000006417
DrugTAAD

FBN1 FBN2

8.45e-0521152CID000133445
DrugCapobenic acid

BOC UBR5

1.41e-0427152CID000030627
Drugfluorocitrate

GRM3 UBR5

1.41e-0427152CID000107647
Drugmelatonin

GRM3 DNAJC7 BOC FBN1

1.63e-04443154CID000000896
Drugrosavin

FBN1 FBN2

1.99e-0432152ctd:C529148
DrugAC1L1D90

BOC FBN2

1.99e-0432152CID000002246
Drugbutandiol

BOC UBR5

1.99e-0432152CID000165788
Drugisodesmosine

FBN1 FBN2

2.11e-0433152CID000013811
DrugNSC49080

FBN1 FBN2

2.11e-0433152CID000002192
Drugvinylglycine

UBR5 FBN1

2.11e-0433152CID000099963
DrugPF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A

GRM3 AKT3 ADAM22

2.45e-041911535917_UP
DrugPHA-00851261E [724719-49-7]; Down 200; 10uM; MCF7; HT_HG-U133A

ALOXE3 AKT3 ADAM22

2.65e-041961533965_DN
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

ALOXE3 ADAM22 FBN2

2.65e-041961535919_UP
DrugRiluzole hydrochloride; Up 200; 14.8uM; MCF7; HT_HG-U133A

AKT3 ADAM22 FBN1

2.65e-041961532295_UP
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A

GRM3 ADAM22 FBN1

2.65e-041961533545_UP
DrugMecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A

GRM3 AKT3 ADAM22

2.69e-041971533525_UP
DrugDelcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A

ADAM22 FBN1 FBN2

2.69e-041971534737_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A

AKT3 ADAM22 FBN1

2.69e-041971535009_UP
DrugLY294002; Down 200; 0.1uM; MCF7; HG-U133A

ALOXE3 AKT3 AQP8

2.69e-04197153424_DN
DrugThioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; MCF7; HT_HG-U133A

GPATCH2 ALOXE3 ADAM22

2.69e-041971534164_DN
DrugChloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ADAM22 FBN1 FBN2

2.73e-041981534414_UP
DrugU-62066 [87151-85-7]; Up 200; 1uM; MCF7; HT_HG-U133A

ALOXE3 ADAM22 FBN1

2.73e-041981534375_UP
DrugCephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A

ALOXE3 ADAM22 FBN1

2.77e-041991536790_UP
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HG-U133A

GPATCH2 UBR5 FBN1

2.77e-041991531935_DN
DrugAmidopyrine [58-15-1]; Up 200; 17.2uM; MCF7; HT_HG-U133A

AKT3 ADAM22 FBN1

2.77e-041991536818_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

GRM3 ALOXE3 AKT3

2.77e-041991532677_UP
Drugchlorosyl

AQP8 KCNA7

2.81e-0438152CID000166686
DrugBAY X 1005

BOC ALOXE3

3.60e-0443152CID000123723
Drugtetramethylbenzidine

BOC FBN1

4.31e-0447152CID003034398
Drugfuniferine N-oxide

FBN1 FBN2

4.68e-0449152CID000191631
DrugRgd Peptide

BOC FBN1 FBN2

4.73e-04239153CID000104802
Druglicofelone

BOC ALOXE3

4.87e-0450152CID000133021
Drugcyclopentyl

BOC UBR5

5.07e-0451152CID000138070
Drugprostacyclin sodium salt

BOC UBR5 ALOXE3

5.40e-04250153CID000000159
Drugdesmosine

FBN1 FBN2

5.48e-0453152CID000025435
Drugtetrahydroisoquinoline

GRM3 BOC

6.11e-0456152CID000007046
DrugCID5255110

GRM3 BOC

6.33e-0457152CID005255110
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

7.23e-073152DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

1.45e-064152DOID:0060249 (is_implicated_in)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2

3.27e-0453152C4707243
Diseasegestational age

GRM3 UBR5

2.19e-03138152EFO_0005112
Diseaseascending aortic diameter

FBN1 FBN2

2.25e-03140152EFO_0021787
Diseaselung non-small cell carcinoma (is_marker_for)

UBR5 AKT3

3.26e-03169152DOID:3908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
DPCAPNEMKNMQPGD

GRM3

511

Q14832
VEDGTPCGPQMMCLE

ADAM22

651

Q9P0K1
MSGEIAMCEPEFGND

AQP8

1

O94778
GMDCMDNERRPHFPQ

AKT3

456

Q9Y243
PGFPCMVDVNSFQEM

ALOXE3

151

Q9BYJ1
GMFSHVDMQPCGPLE

KCNA7

411

Q96RP8
MGPEDEGVYQCMAEN

BOC

381

Q9BWV1
TCEEGFEPGPMMTCE

FBN1

2191

P35555
FEPGPMMTCEDINEC

FBN1

2196

P35555
QDLDEEGMNMGDFDP

DNAJC7

451

Q99615
ECNCNEGFEPGPMMN

FBN2

2236

P35556
EGFEPGPMMNCEDIN

FBN2

2241

P35556
MTQPPEGCRDQDMDS

GPATCH2

181

Q9NW75
EEMNGAPMPDIQVYG

MOXD2P

371

A6NHM9
NPMPCEAGCPAGMEV

SSPOP

4056

A2VEC9
TAMPMSVEEGPECQG

POLR1H

66

Q9P1U0
EDVFMGMVCPSGTNP

UBR5

1151

O95071