Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

3.98e-06120706GO:0004222
GeneOntologyMolecularFunctionimportin-alpha family protein binding

GOLGA6C GOLGA6D GOLGA6B

5.24e-0521703GO:0061676
GeneOntologyMolecularFunctionmetallopeptidase activity

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

7.21e-05200706GO:0008237
GeneOntologyMolecularFunctionzinc ion binding

MMP28 MMP27 ZNF205 LHX3 MMP1 MMP2 MMP7 MMP8 NOS1 TET3 TRIM3

2.55e-048917011GO:0008270
GeneOntologyMolecularFunctionmicrotubule binding

TTBK2 KIF9 GOLGA6C GOLGA6D GOLGA6B MTCL1

7.35e-04308706GO:0008017
GeneOntologyMolecularFunctiontubulin binding

TTBK2 KIF9 GOLGA6C GOLGA6D GOLGA6B MTCL1 GNAS

7.42e-04428707GO:0015631
GeneOntologyMolecularFunctioncalcium channel regulator activity

RRAD REM2 NOS1

9.00e-0454703GO:0005246
GeneOntologyBiologicalProcesscollagen catabolic process

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.74e-0853666GO:0030574
GeneOntologyBiologicalProcessregulation of protein glycosylation

ABCA2 GOLGA6C GOLGA6D GOLGA6B

9.68e-0724664GO:0060049
GeneOntologyBiologicalProcesscellular component disassembly

TTBK2 KIF9 MTRFR GOLGA6C GOLGA6D GOLGA6B MMP1 MMP2 MMP7 MMP8 KLHDC10

3.79e-066176611GO:0022411
GeneOntologyBiologicalProcessextracellular matrix disassembly

KIF9 MMP1 MMP2 MMP7 MMP8

4.17e-0675665GO:0022617
GeneOntologyBiologicalProcesspositive regulation of glycoprotein biosynthetic process

ABCA2 GOLGA6C GOLGA6D GOLGA6B

5.21e-0636664GO:0010560
GeneOntologyBiologicalProcesscollagen metabolic process

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

7.86e-06148666GO:0032963
GeneOntologyBiologicalProcesspositive regulation of glycoprotein metabolic process

ABCA2 GOLGA6C GOLGA6D GOLGA6B

8.01e-0640664GO:1903020
GeneOntologyBiologicalProcessGolgi disassembly

GOLGA6C GOLGA6D GOLGA6B

2.47e-0518663GO:0090166
GeneOntologyBiologicalProcessextracellular matrix organization

COL4A6 KIF9 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.63e-05377668GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL4A6 KIF9 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.68e-05378668GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL4A6 KIF9 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.74e-05379668GO:0045229
GeneOntologyBiologicalProcesspositive regulation of protein glycosylation

GOLGA6C GOLGA6D GOLGA6B

2.92e-0519663GO:0060050
GeneOntologyBiologicalProcessprotein tetramerization

CRTC3 PKD1 GOLGA6C GOLGA6D GOLGA6B

3.09e-05113665GO:0051262
GeneOntologyBiologicalProcessorganelle disassembly

KIF9 MTRFR GOLGA6C GOLGA6D GOLGA6B KLHDC10

4.82e-05204666GO:1903008
GeneOntologyBiologicalProcessGolgi ribbon formation

GOLGA6C GOLGA6D GOLGA6B

5.29e-0523663GO:0090161
GeneOntologyBiologicalProcessregulation of glycoprotein biosynthetic process

ABCA2 GOLGA6C GOLGA6D GOLGA6B

7.07e-0569664GO:0010559
GeneOntologyBiologicalProcessGolgi localization

GOLGA6C GOLGA6D GOLGA6B

8.66e-0527663GO:0051645
GeneOntologyBiologicalProcessmeiotic spindle assembly

GOLGA6C GOLGA6D GOLGA6B

9.68e-0528663GO:0090306
GeneOntologyBiologicalProcessorganelle inheritance

GOLGA6C GOLGA6D GOLGA6B

9.68e-0528663GO:0048308
GeneOntologyBiologicalProcessGolgi inheritance

GOLGA6C GOLGA6D GOLGA6B

9.68e-0528663GO:0048313
GeneOntologyBiologicalProcessprotein homotetramerization

CRTC3 GOLGA6C GOLGA6D GOLGA6B

1.09e-0477664GO:0051289
GeneOntologyBiologicalProcessregulation of glycoprotein metabolic process

ABCA2 GOLGA6C GOLGA6D GOLGA6B

1.26e-0480664GO:1903018
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

FNDC1 LARP4B ABCA2 BBS7 ANGPT4 SRC PRR5 GOLGA6C GOLGA6D GOLGA6B GNAS SLC39A10 NOS1 DNAJC3

1.74e-0414586614GO:0051247
GeneOntologyBiologicalProcessasymmetric cell division

GOLGA6C GOLGA6D GOLGA6B

1.74e-0434663GO:0008356
GeneOntologyBiologicalProcessresponse to fluid shear stress

SRC PKD1 MMP2

1.90e-0435663GO:0034405
GeneOntologyBiologicalProcessregulation of protein modification process

FNDC1 ABCA2 DBNDD1 ANGPT4 SRC PRR5 GOLGA6C GOLGA6D GOLGA6B GNAS SLC39A10 CMYA5 NOS1 DNAJC3

2.15e-0414886614GO:0031399
GeneOntologyBiologicalProcessmeiotic spindle organization

GOLGA6C GOLGA6D GOLGA6B

2.25e-0437663GO:0000212
GeneOntologyBiologicalProcessorganelle assembly

TTBK2 KIF9 NPTX1 MDN1 CELSR2 BBS7 SRC GOLGA6C GOLGA6D GOLGA6B LRRTM1 DNAAF1

2.32e-0411386612GO:0070925
GeneOntologyBiologicalProcessnegative regulation of molecular function

TTBK2 ABCA2 DBNDD1 SRC GOLGA6C GOLGA6D GOLGA6B RRAD CMYA5 NOS1 DNAJC3

3.19e-0410056611GO:0044092
GeneOntologyBiologicalProcessprotein complex oligomerization

CRTC3 KCNA6 PKD1 GOLGA6C GOLGA6D GOLGA6B

3.66e-04296666GO:0051259
GeneOntologyBiologicalProcessnegative regulation of protein binding

TTBK2 GOLGA6C GOLGA6D GOLGA6B

3.72e-04106664GO:0032091
GeneOntologyBiologicalProcesscellular response to UV-A

MMP1 MMP2

5.44e-0411662GO:0071492
GeneOntologyBiologicalProcesshead development

TTBK2 FAT4 SPHK2 CELSR2 BBS7 SRC GAS1 LHX3 MMP2 BCR

6.42e-049196610GO:0060322
GeneOntologyBiologicalProcesshippo signaling

FAT4 SHANK2 SRC

7.29e-0455663GO:0035329
GeneOntologyBiologicalProcesspositive regulation of protein modification process

FNDC1 ANGPT4 SRC PRR5 GOLGA6C GOLGA6D GOLGA6B GNAS SLC39A10 NOS1

7.46e-049376610GO:0031401
GeneOntologyBiologicalProcessprotein homooligomerization

CRTC3 KCNA6 GOLGA6C GOLGA6D GOLGA6B

7.54e-04224665GO:0051260
GeneOntologyBiologicalProcesscellular response to ketone

SPHK2 SRC GNAS NPAS4

8.03e-04130664GO:1901655
GeneOntologyBiologicalProcessmicrotubule nucleation

GOLGA6C GOLGA6D GOLGA6B

8.09e-0457663GO:0007020
GeneOntologyBiologicalProcessregulation of protein binding

TTBK2 SRC GOLGA6C GOLGA6D GOLGA6B

8.16e-04228665GO:0043393
GeneOntologyBiologicalProcesspostsynaptic density organization

NPTX1 SHANK2 LRRTM1

8.51e-0458663GO:0097106
GeneOntologyBiologicalProcessregulation of toll-like receptor 3 signaling pathway

SRC TRIM3

8.95e-0414662GO:0034139
GeneOntologyCellularComponentextracellular matrix

COL4A6 MMP28 ANGPT4 MMP27 LRRTM1 MMP1 MMP2 MMP7 MMP8 MUC4

4.87e-056566810GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A6 MMP28 ANGPT4 MMP27 LRRTM1 MMP1 MMP2 MMP7 MMP8 MUC4

5.00e-056586810GO:0030312
GeneOntologyCellularComponentGolgi cis cisterna

GOLGA6C GOLGA6D GOLGA6B

1.67e-0433683GO:0000137
GeneOntologyCellularComponentcell projection membrane

SLC9A3 SHANK2 BBS7 SRC PKD1 ARHGAP45 MUC4

4.95e-04431687GO:0031253
GeneOntologyCellularComponentspindle pole

GOLGA6C GOLGA6D GOLGA6B MTCL1 DNAAF1

5.46e-04205685GO:0000922
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

SRC BCR NOS1

8.07e-0456683GO:0099091
MousePhenoincreased alveolar macrophage number

GOLGA6C GOLGA6D GOLGA6B

2.27e-0514573MP:0014228
MousePhenoabnormal cerebellar cortex morphology

SHANK2 GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 GNAS CMYA5

2.72e-05300578MP:0004097
MousePhenoabnormal alveolar macrophage number

GOLGA6C GOLGA6D GOLGA6B

2.82e-0515573MP:0014227
MousePhenoabnormal dendrite morphology

SHANK2 GAS1 MTCL1 LRRTM1 CMYA5 REM2 NOS1

4.73e-05237577MP:0008143
MousePhenoabnormal cerebellar layer morphology

SHANK2 GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 CMYA5

9.12e-05263577MP:0009956
MousePhenoabnormal Golgi vesicle transport

GOLGA6C GOLGA6D GOLGA6B

9.37e-0522573MP:0030949
MousePhenoabnormal proacrosomal vesicle fusion

GOLGA6C GOLGA6D GOLGA6B

1.22e-0424573MP:0031355
MousePhenoabnormal cerebellum morphology

SHANK2 GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 GNAS CMYA5

1.68e-04389578MP:0000849
MousePhenoabnormal Purkinje cell morphology

GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 CMYA5

1.75e-04204576MP:0000877
MousePhenoabnormal alveolar macrophage morphology

GOLGA6C GOLGA6D GOLGA6B

1.75e-0427573MP:0008245
MousePhenoabsent sperm mitochondrial sheath

GOLGA6C GOLGA6D GOLGA6B

1.96e-0428573MP:0009833
MousePhenoabnormal renal water reabsorption

SLC9A3 NOS1

2.42e-046572MP:0010108
MousePhenoabnormal cerebellar Purkinje cell layer

GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 CMYA5

2.64e-04220576MP:0000875
MousePhenoabnormal metencephalon morphology

SHANK2 GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 GNAS CMYA5

2.82e-04420578MP:0000847
MousePhenoabsent acrosome

GOLGA6C GOLGA6D GOLGA6B

2.93e-0432573MP:0008839
MousePhenoabnormal Golgi apparatus morphology

GOLGA6C GOLGA6D GOLGA6B

3.22e-0433573MP:0011743
MousePhenoabnormal actin cytoskeleton morphology

GOLGA6C GOLGA6D GOLGA6B

3.52e-0434573MP:0020849
MousePhenoabnormal neurite morphology

ABCA2 SHANK2 GAS1 MTCL1 LRRTM1 CMYA5 REM2 NOS1

3.98e-04442578MP:0008415
MousePhenoabnormal liver parenchyma morphology

PKD1 GOLGA6C GOLGA6D GOLGA6B BCR NOS1

4.48e-04243576MP:0008986
MousePhenoabnormal leukocyte migration

SPHK2 MMP28 MMP7 ARHGAP45 NOS1

5.06e-04162575MP:0003156
MousePhenoabnormal hepatocyte morphology

PKD1 GOLGA6C GOLGA6D GOLGA6B NOS1

5.65e-04166575MP:0000607
MousePhenoabnormal renal water transport

SLC9A3 NOS1

5.77e-049572MP:0011443
MousePhenoabnormal inflammatory response

SRC PKD1 KPRP MMP1 MMP2 GNAS MMP7 MMP8 KLHDC10 BCR MUC4 NOS1 DNAJC3 SBSN

6.14e-0413105714MP:0001845
MousePhenoabnormal social investigation

SHANK2 SRC LRRTM1 CMYA5 PREX1

6.47e-04171575MP:0001360
MousePhenoabnormal motor coordination/balance

ABCA2 SHANK2 SRC GAS1 GOLGA6C GOLGA6D GOLGA6B GRXCR1 MTCL1 GNAS NOS1

6.90e-048735711MP:0001516
MousePhenoabnormal renal water homeostasis

SLC9A3 NOS1

7.20e-0410572MP:0011444
MousePhenodecreased sperm progressive motility

KIF9 GOLGA6C GOLGA6D GOLGA6B

7.28e-04100574MP:0020451
MousePhenoabnormal hindbrain morphology

SHANK2 GAS1 GOLGA6C GOLGA6D GOLGA6B MTCL1 GNAS CMYA5

7.34e-04485578MP:0000841
MousePhenoabnormal sperm progressive motility

KIF9 GOLGA6C GOLGA6D GOLGA6B

7.56e-04101574MP:0020450
DomainPG_binding_1

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

5.23e-1120656PF01471
DomainPeptidoglycan-bd-like

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

5.23e-1120656IPR002477
DomainM10A_MMP

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.35e-1023656IPR033739
DomainPept_M10A

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.35e-1023656IPR021190
DomainPeptidase_M10

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.80e-1024656PF00413
DomainZnMc

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

6.26e-1029656SM00235
DomainPeptidase_Metallo

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

6.26e-1029656IPR006026
DomainPept_M10A_Zn_BS

MMP27 MMP1 MMP2 MMP7 MMP8

1.28e-0915655IPR021158
DomainCYSTEINE_SWITCH

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

5.73e-0941656PS00546
DomainPept_M10_metallopeptidase

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

7.73e-0943656IPR001818
DomainHemopexin-like_dom

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655IPR000585
DomainHemopexin-like_repeat

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655IPR018487
DomainHemopexin

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655PF00045
DomainHEMOPEXIN

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655PS00024
Domain-

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-08236552.110.10.10
DomainHEMOPEXIN_2

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655PS51642
DomainHX

MMP28 MMP27 MMP1 MMP2 MMP8

1.40e-0823655SM00120
DomainHemopexin_CS

MMP27 MMP1 MMP2 MMP8

3.07e-0717654IPR018486
DomainMetalloPept_cat_dom

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

3.71e-0781656IPR024079
Domain-

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

3.71e-07816563.40.390.10
DomainPept_M10A_stromelysin-type

MMP28 MMP27 MMP1 MMP8

3.94e-0718654IPR016293
DomainZINC_PROTEASE

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.15e-0698656PS00142
DomainGOLGA2L5

GOLGA6C GOLGA6D GOLGA6B

3.16e-0518653PF15070
DomainGolgin_A

GOLGA6C GOLGA6D GOLGA6B

3.16e-0518653IPR024858
DomainSmall_GTPase_GEM/REM/Rad

RRAD REM2

7.12e-054652IPR017358
Domain-

MMP28 MMP2

7.12e-0546521.10.101.10
DomainPAS_fold_3

NPAS4 KCNH4

2.88e-0323652IPR013655
DomainPAS_3

NPAS4 KCNH4

2.88e-0323652PF08447
DomainPAS-assoc_C

NPAS4 KCNH4

3.13e-0324652IPR000700
DomainPAC

NPAS4 KCNH4

3.67e-0326652PS50113
DomainhEGF

FAT4 CELSR2

4.25e-0328652PF12661
Domain-

FAT4 NPTX1 CELSR2

4.43e-03956532.60.120.200
DomainLRR

LRCH2 PKD1 LRRTM1 DNAAF1

5.28e-03201654PS51450
DomainPAS

NPAS4 KCNH4

5.53e-0332652SM00091
PathwayWP_MATRIX_METALLOPROTEINASES

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

7.38e-1029516MM15981
PathwayWP_MATRIX_METALLOPROTEINASES

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

9.20e-1030516M39652
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.39e-0846516M46450
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A6 MMP1 MMP2 MMP7 MMP8

1.28e-0653515MM14566
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A6 MMP1 MMP2 MMP7 MMP8

3.29e-0664515M26953
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

MMP1 MMP2 MMP7 MMP8

5.75e-0633514M26976
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

MMP1 MMP2 MMP7 MMP8

1.02e-0538514MM14611
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A6 MMP1 MMP2 MMP7 MMP8

5.53e-05114515MM14571
PathwayREACTOME_GOLGI_CISTERNAE_PERICENTRIOLAR_STACK_REORGANIZATION

GOLGA6C GOLGA6D GOLGA6B

7.51e-0523513MM14620
PathwayREACTOME_RHOD_GTPASE_CYCLE

PAK5 GOLGA6C GOLGA6D GOLGA6B

8.23e-0564514MM15601
PathwayWP_RAC1PAK1P38MMP2_PATHWAY

ANGPT4 SRC MMP2 NOS1

1.04e-0468514M39456
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A6 MMP1 MMP2 MMP7 MMP8

1.46e-04140515M587
PathwayWP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT

PAK5 MMP2 MMP8

4.01e-0440513M39798
PathwayWP_BLADDER_CANCER

SRC MMP1 MMP2

4.01e-0440513M39523
PathwayWP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER

PAK5 MMP2 MMP8

4.97e-0443513M39788
PathwayPID_SYNDECAN_1_PATHWAY

COL4A6 MMP1 MMP7

6.07e-0446513M198
PathwayREACTOME_RHO_GTPASE_CYCLE

PAK5 GOLGA6C GOLGA6D GOLGA6B BCR ARHGAP45 PREX1

9.59e-04439517MM15595
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

3.88e-122270623421805
Pubmed

Matrix metalloproteinases: structures, evolution, and diversification.

MMP1 MMP2 MMP7 MMP8

7.51e-1157049737711
Pubmed

Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families.

MMP27 MMP1 MMP2 MMP7 MMP8

1.23e-101670520484597
Pubmed

Matrix remodeling by MMPs during wound repair.

MMP1 MMP2 MMP7 MMP8

5.24e-10770425770908
Pubmed

Matrix metalloproteinases.

MMP27 MMP1 MMP2 MMP7 MMP8

7.32e-102270510419448
Pubmed

Characterization of opticin digestion by proteases involved in osteoarthritis development.

MMP1 MMP2 MMP7 MMP8

1.05e-09870423845380
Pubmed

Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites.

MMP1 MMP2 MMP7 MMP8

1.88e-09970410986281
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MDN1 SHANK2 LRCH2 CELSR2 PAK5 SRC GOLGA6C GOLGA6D GOLGA6B MTCL1 LRRTM1 BCR NOS1 TRIM3

6.49e-09963701428671696
Pubmed

MMP1, 2, 3, 7, and 9 gene polymorphisms and urinary cancer risk: a meta-analysis.

MMP1 MMP2 MMP7

7.81e-09370326301605
Pubmed

Expression of Matrix Metalloproteinases in Intraductal Papillary Mucinous Neoplasm of the Pancreas.

MMP1 MMP2 MMP7

7.81e-09370331366549
Pubmed

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.

MMP1 MMP2 MMP7 MMP8

2.69e-081670437701782
Pubmed

Distribution of matrix metalloproteinases MMP-1, MMP-2, MMP-8 and tissue inhibitor of matrix metalloproteinases-2 in nasal polyposis and chronic rhinosinusitis.

MMP1 MMP2 MMP8

3.12e-08470321432777
Pubmed

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review.

MMP1 MMP2 MMP7

3.12e-08470325352026
Pubmed

Polymorphism of Matrix Metalloproteinases Genes MMP1, MMP2, MMP3, and MMP7 and the Risk of Varicose Veins of Lower Extremities.

MMP1 MMP2 MMP7

3.12e-08470328944430
Pubmed

Genetic polymorphisms of matrix metalloproteinases: susceptibility and prognostic implications for prostate cancer.

MMP1 MMP2 MMP7

3.12e-08470319303106
Pubmed

Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs.

MMP1 MMP2 MMP7

3.12e-08470325263962
Pubmed

Expression spectra of matrix metalloproteinases in metastatic non-small cell lung cancer.

MMP1 MMP2 MMP7

3.12e-08470315375490
Pubmed

Expression of metalloproteinases 1, 2, 7, 9, and 12 in human cytotrophoblastic cells from normal and preeclamptic placentas.

MMP1 MMP2 MMP7

7.79e-08570322936257
Pubmed

Clinical impact of MMP and TIMP gene polymorphisms in gastric cancer.

MMP2 MMP7 MMP8

1.55e-07670316940985
Pubmed

Matrix metalloproteinase polymorphisms and bladder cancer risk.

MMP1 MMP2 MMP8

1.55e-07670317178858
Pubmed

Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population.

MMP1 MMP2 MMP7

1.55e-07670319132754
Pubmed

The effect of epidermal growth factor on matrix metalloproteinases and tissue inhibitors of metalloproteinase gene expression in cultured human gingival fibroblasts.

MMP1 MMP2 MMP7

1.55e-07670317181997
Pubmed

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan.

MMP1 MMP2 MMP8

1.55e-0767037998967
Pubmed

Single nucleotide polymorphisms in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis.

MMP1 MMP2 MMP7

1.55e-07670319643940
Pubmed

Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness.

MMP1 MMP2 MMP8

1.55e-07670317473191
Pubmed

Expression of matrix metalloproteinases in ovarian endometriomas: immunohistochemical study and enzyme immunoassay.

MMP1 MMP2 MMP7

1.55e-07670312034345
Pubmed

UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors.

CELSR2 GOLGA6C GOLGA6D GOLGA6B

2.18e-072670419474315
Pubmed

Fine physical mapping of the human matrix metalloproteinase genes clustered on chromosome 11q22.3.

MMP1 MMP7 MMP8

2.72e-0777038921407
Pubmed

Expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinases during mouse embryonic development.

MMP1 MMP2 MMP8

2.72e-07770317307908
Pubmed

Matrix metalloproteinases cleave tissue factor pathway inhibitor. Effects on coagulation.

MMP1 MMP7 MMP8

2.72e-07770310859319
Pubmed

Expression of matrix metalloproiteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in hepatocellular carcinoma tissue, compared with the surrounding non-tumor tissue.

MMP1 MMP2 MMP7

2.72e-07770317564313
Pubmed

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain.

MMP1 MMP7 MMP8

2.72e-0777038216228
Pubmed

Functional polymorphisms and haplotypes in the promoter of the MMP2 gene are associated with risk of nasopharyngeal carcinoma.

MMP1 MMP2 MMP7

2.72e-07770317607721
Pubmed

Regulatory polymorphisms in extracellular matrix protease genes and susceptibility to rheumatoid arthritis: a case-control study.

MMP1 MMP2 MMP7

4.34e-07870316356191
Pubmed

Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion.

SRC MMP2 MMP7

6.50e-07970318713744
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP1 MMP2 MMP7 MMP8

8.44e-073670420587546
Pubmed

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.

GOLGA6C GOLGA6D GOLGA6B MMP2

1.30e-064070430578393
Pubmed

The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis.

CELSR2 GOLGA6C GOLGA6D GOLGA6B

1.44e-064170430022023
Pubmed

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.

SRC GOLGA6C GOLGA6D GOLGA6B

1.59e-064270424210661
Pubmed

Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo.

MMP1 MMP2 MMP8

1.70e-061270312149192
Pubmed

Globozoospermia and lack of acrosome formation in GM130-deficient mice.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370328055014
Pubmed

GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370333740186
Pubmed

Loss of GM130 does not impair oocyte meiosis and embryo development in mice.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370332873390
Pubmed

GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370321552007
Pubmed

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370328028212
Pubmed

Differential expression of tissue inhibitor of metalloproteinases type 1 (TIMP-1) during mouse gonad development.

MMP1 MMP2 MMP7

2.20e-061370312815621
Pubmed

GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.

GOLGA6C GOLGA6D GOLGA6B

2.20e-061370329128360
Pubmed

The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.

GOLGA6C GOLGA6D GOLGA6B DNAJC3

2.51e-064770429180572
Pubmed

Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.

GOLGA6C GOLGA6D GOLGA6B

2.80e-061470337831422
Pubmed

Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice.

MMP1 MMP2 MMP8

2.80e-061470316236725
Pubmed

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.

GOLGA6C GOLGA6D GOLGA6B

2.80e-061470330630895
Pubmed

Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.

GOLGA6C GOLGA6D GOLGA6B

2.80e-061470327226319
Pubmed

Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation.

MMP2 MMP7 MMP8

2.80e-061470325636537
Pubmed

Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.

GOLGA6C GOLGA6D GOLGA6B

2.80e-061470333543287
Pubmed

Golgi disruption and early embryonic lethality in mice lacking USO1.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570323185636
Pubmed

The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570317046993
Pubmed

Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570317189423
Pubmed

WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570337635409
Pubmed

Golga5 is dispensable for mouse embryonic development and postnatal survival.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570328509431
Pubmed

GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570326165940
Pubmed

Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570317204322
Pubmed

Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570316413118
Pubmed

uPARAP expression during murine lung development.

MMP28 MMP2 MMP7

3.49e-061570318639653
Pubmed

RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.

GOLGA6C GOLGA6D GOLGA6B

3.49e-061570326083584
Pubmed

[Matrix metalloproteinases regulations of human gingival fibroblasts by Porphyromonas gingivalis with different fimA genotypes].

MMP1 MMP2

3.99e-06270219134348
Pubmed

Association of Polymorphisms of the Tissue Inhibitors of Metalloproteinases- 1 and -2 with Alzheimer's Disease in Taiwan.

MMP1 MMP2

3.99e-06270234561981
Pubmed

HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors.

MMP2 MMP7

3.99e-06270211220743
Pubmed

Evaluation of MMP-7 A-181G and MMP-2 C-735T polymorphisms in healthy population from western Iran.

MMP2 MMP7

3.99e-06270226950446
Pubmed

Compound K inhibits MMP-1 expression through suppression of c-Src-dependent ERK activation in TNF-α-stimulated dermal fibroblast.

SRC MMP1

3.99e-06270225181017
Pubmed

Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma.

SRC GNAS

3.99e-06270238097740
Pubmed

Gene-expression analysis of matrix metalloproteinases 1 and 2 and their tissue inhibitors in chronic periapical inflammatory lesions.

MMP1 MMP2

3.99e-06270226293377
Pubmed

Absence of MMP2 expression correlates with poor clinical outcomes in rectal cancer, and is distinct from MMP1-related outcomes in colon cancer.

MMP1 MMP2

3.99e-06270221531813
Pubmed

Release of matrix metalloproteinases-1 and -2, but not -9, from activated platelets measured by enzyme-linked immunosorbent assay.

MMP1 MMP2

3.99e-06270221756063
Pubmed

Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells.

MMP1 MMP8

3.99e-06270219708869
Pubmed

Genetic polymorphisms in Matrix Metalloproteinases -1 and -7 and susceptibility to gastric cancer: an association study and meta-analysis.

MMP1 MMP7

3.99e-06270223893803
Pubmed

Fluid shear stress regulates the invasive potential of glioma cells via modulation of migratory activity and matrix metalloproteinase expression.

MMP1 MMP2

3.99e-06270221637818
Pubmed

[Expression of parodontal tissue matrix metalloproteinases-1,2 in adolescent and their role in gingival pathology].

MMP1 MMP2

3.99e-06270223676485
Pubmed

Association Study between the Polymorphisms of Matrix Metalloproteinase (MMP) Genes and Idiopathic Recurrent Pregnancy Loss.

MMP27 MMP8

3.99e-06270231067818
Pubmed

Identification of MMP1 and MMP2 by RNA-seq analysis in laryngeal squamous cell carcinoma.

MMP1 MMP2

3.99e-06270231932027
Pubmed

Matrix metalloproteinase messenger RNA expression in human endometriosis grafts cultured on a chicken chorioallantoic membrane.

MMP1 MMP2

3.99e-06270219345347
Pubmed

Influence of matrix metalloproteinase gene polymorphisms in healthy North Indians compared to variations in other ethnic groups worldwide.

MMP1 MMP7

3.99e-06270220192597
Pubmed

[The study of activity of matrix metalloproteinases abd reactants of inflammation in patients with endocarditis.].

MMP2 MMP7

3.99e-06270230689319
Pubmed

Expression of matrix metalloproteinases 7 and 2 in human renal cell carcinoma.

MMP2 MMP7

3.99e-06270212684625
Pubmed

Correlations of MMP-1 and MMP-2 gene polymorphisms with essential hypertension.

MMP1 MMP2

3.99e-06270231124635
Pubmed

[Plasma matrix metalloproteinases-2 and -9 levels are elevated in patients with acute coronary syndrome and coronary chronic total occlusion].

MMP2 MMP8

3.99e-06270219460733
Pubmed

The matrix metalloproteinase-7 and pro-enzyme of metalloproteinase-1 as a potential marker for patients with rectal cancer without distant metastasis.

MMP1 MMP7

3.99e-06270225549795
Pubmed

Matrix metalloproteinase-1 (MMP-1) and (MMP-8) gene polymorphisms promote increase and remodeling of the collagen III and V in posterior tibial tendinopathy.

MMP1 MMP8

3.99e-06270229532899
Pubmed

MMP-2 (-1306 C/T) Polymorphism Affects Serum Matrix Metalloproteinase (MMP)-2 Levels and Correlates with Chronic Obstructive Pulmonary Disease Severity: A Case-Control Study of MMP-1 and -2 in a Tunisian Population.

MMP1 MMP2

3.99e-06270227412345
Pubmed

[Polymorphism of metalloproteinases MMP-1 and MMP-2 in risk of laryngeal cancer].

MMP1 MMP2

3.99e-06270223164104
Pubmed

Matrix metalloproteinases gene polymorphism haplotype is a risk factor to implant loss: A case-control study.

MMP1 MMP8

3.99e-06270230328228
Pubmed

Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India.

MMP2 MMP8

3.99e-06270221784671
Pubmed

[Change of matrix metalloproteinase-1 and matrix metalloproteinase-7 in serum and bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and sarcoidosis].

MMP1 MMP7

3.99e-06270220979817
Pubmed

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.

MMP1 MMP7

3.99e-06270218447576
Pubmed

Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis.

MMP1 MMP7

3.99e-06270223644699
Pubmed

Shank2 associates with and regulates Na+/H+ exchanger 3.

SLC9A3 SHANK2

3.99e-06270216293618
Pubmed

Matrix metalloproteinase (MMP)-7 activates MMP-8 but not MMP-13.

MMP7 MMP8

3.99e-06270217017992
Pubmed

Bladder cancer risk associated with genotypic polymorphism of the matrix metalloproteinase-1 and 7 in North Indian population.

MMP1 MMP7

3.99e-06270220826916
Pubmed

Modulation of monocyte matrix metalloproteinase-2 by breast adenocarcinoma cells.

MMP1 MMP2

3.99e-06270216168111
Pubmed

Clinical Significance of Matrix Metalloproteinases in Blood Plasma of Patients with Gastric Cancer.

MMP2 MMP7

3.99e-06270230627896
Pubmed

LIM kinase 2 is widely expressed in all tissues.

GOLGA6C GOLGA6D GOLGA6B

4.29e-061670316399995
InteractionMMP8 interactions

MMP27 MMP1 MMP2 MMP7 MMP8

2.20e-0825705int:MMP8
InteractionMMP27 interactions

MMP27 MMP1 MMP2 MMP8

4.32e-0811704int:MMP27
InteractionMMP9 interactions

COL4A6 MMP27 MMP1 MMP2 MMP7 MMP8

1.19e-0767706int:MMP9
InteractionMMP1 interactions

MMP27 MMP1 MMP2 MMP7 MMP8

1.75e-0737705int:MMP1
InteractionMMP16 interactions

MMP27 MMP1 MMP7 MMP8

3.94e-0718704int:MMP16
InteractionMMP24 interactions

MMP27 MMP1 MMP7 MMP8

4.97e-0719704int:MMP24
InteractionMMP2 interactions

COL4A6 MMP27 MMP1 MMP2 MMP7 MMP8

5.71e-0787706int:MMP2
InteractionMMP10 interactions

NPTX1 MMP27 MMP2 MMP7

3.42e-0630704int:MMP10
InteractionBCAN interactions

MMP1 MMP2 MMP7 MMP8

7.23e-0636704int:BCAN
InteractionCLRN3 interactions

GOLGA6C GOLGA6D GOLGA6B

1.12e-0513703int:CLRN3
InteractionMMP7 interactions

MMP1 MMP2 MMP7 MMP8

1.95e-0546704int:MMP7
InteractionACAN interactions

MMP1 MMP2 MMP8

5.89e-0522703int:ACAN
InteractionTFPI interactions

MMP1 MMP7 MMP8

1.11e-0427703int:TFPI
InteractionADRB3 interactions

SRC GNAS

1.77e-046702int:ADRB3
InteractionCEACAM21 interactions

FAT4 CELSR2 SRC CCDC51

1.81e-0481704int:CEACAM21
CytobandEnsembl 112 genes in cytogenetic band chr11q22

MMP27 MMP1 MMP7 MMP8

2.27e-05107704chr11q22
CytobandEnsembl 112 genes in cytogenetic band chr15q24

GOLGA6C GOLGA6D GOLGA6B

8.80e-04122703chr15q24
Cytoband15q24.2

GOLGA6C GOLGA6D

1.10e-033270215q24.2
Cytoband11q22.3

MMP1 MMP8

2.08e-034470211q22.3
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.88e-1124476891
GeneFamilyRGK type GTPase family

RRAD REM2

3.96e-0544721260
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A6 BBS7 MMP27 MTCL1 MMP8

7.63e-06172705f814b6134ad608015765399d54cc1e5e1873ed34
ToppCellNS-moderate-d_16-33-Lymphoid-NK|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GAS1 LRRTM1 MMP1 MMP2 NOS1

1.00e-05182705fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD NPAS4

1.23e-05190705938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 KIF9 RRAD DNAAF1 MUC4

1.23e-051907052fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

BICDL2 SHANK2 MMP1 MMP7 MUC4

1.30e-0519270559261098ccb52306f837f632ebaea45b90ad30fe
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A6 CELSR2 MMP1 MMP7 CMYA5

1.43e-051967053b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 SHANK2 LRRTM1 MMP2 MUC4

1.47e-051977051da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A6 CELSR2 MMP1 MMP7 CMYA5

1.47e-0519770524360b660000bdfb999d58fbf4e29585a97e1785
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CELSR2 GOLGA2P5 CCDC51 NPAS4

5.59e-05132704a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NPTX1 MTCL1 MMP2 CMYA5

1.09e-04157704b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

FNDC1 NPTX1 MMP7 IFNLR1

1.12e-04158704ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMP27 MMP1 MMP2 CMYA5

1.39e-04167704805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMP27 MMP1 MMP2 CMYA5

1.39e-0416770431cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMP27 MMP1 MMP2 CMYA5

1.39e-041677043acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A6 CELSR2 MMP1 MMP7

1.42e-0416870448089fa2d4a0f31a72405717119b767a92571f01
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF9 KLHDC10 ARHGAP45 REM2

1.49e-041707040f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 MMP27 MMP2 SBSN

1.49e-04170704d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR5 PLEKHA2 ARHGAP45 PREX1

1.66e-04175704f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 MMP27 MMP2 SBSN

1.70e-04176704c0a084f7a8645262d61971f094689e02bf15b113
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 MMP27 MMP2 SBSN

1.70e-04176704cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF787 SRC ADAT1 TRIM3

1.85e-04180704be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF787 SRC ADAT1 TRIM3

1.85e-041807043b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FNDC1 MMP2 RRAD

1.85e-0418070412537d8a569faa69f474284d2c201475722b8ca1
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

KCNA6 GNAS RRAD BCR

1.85e-041807040b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A6 FNDC1 MTCL1 RRAD

1.89e-0418170425915e2500430a902db37d79a749ce2990b69810
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANGPT4 GAS1 MMP27 MMP2

1.93e-04182704e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

FNDC1 MMP28 GAS1 MMP2

1.93e-04182704354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD

1.97e-04183704a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF9 RRAD MMP7 DNAAF1

1.97e-0418370458847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A6 MMP1 MMP7 MUC4

2.01e-041847041f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 SLC9A3 CMYA5 MUC4

2.01e-0418470401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 KCNA6 MMP2 IFNLR1

2.05e-04185704ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A6 SHANK2 MTCL1 MMP7

2.05e-041857040d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 FNDC1 ANGPT4 RRAD

2.05e-041857040b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

SLC38A10 RRAD DNAAF1 DNAJC3

2.10e-04186704f4d72463c5f287da6436287eda0a349b4185841e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC1 ANGPT4 MTCL1 RRAD

2.10e-041867046add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A6 SHANK2 MTCL1 MMP7

2.10e-04186704e83718fabb057100835d3357df407f283d23fe16
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

COL4A6 SHANK2 MMP1 MUC4

2.14e-041877048407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC1 ANGPT4 MTCL1 RRAD

2.18e-041887043177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FNDC1 ANGPT4 MTCL1 RRAD

2.18e-04188704293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD

2.18e-04188704f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellFibroblast-C|World / shred on cell class and cell subclass (v4)

FNDC1 GAS1 MMP2 SBSN

2.23e-0418970458e0400fbab5a0755504275aef5cf7986149abab
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

BICDL2 SHANK2 MMP7 MUC4

2.23e-0418970484d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF9 RRAD DNAAF1 MUC4

2.23e-04189704b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

COL4A6 FNDC1 MTCL1 RRAD

2.27e-04190704645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PRR5 MMP2 GNAS CMYA5

2.27e-041907049ce301841ce9486701fa28eb2a9929e35d476878
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 SLC9A3 CMYA5 MUC4

2.27e-0419070423f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BICDL2 SLC9A3 CMYA5 MUC4

2.27e-041907043c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A6 FNDC1 GAS1 MMP2

2.32e-041917042b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

BICDL2 SHANK2 MMP7 MUC4

2.32e-04191704c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF9 RRAD DNAAF1 MUC4

2.32e-04191704683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A3 SHANK2 MTCL1 NOS1

2.32e-04191704963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

BICDL2 SHANK2 MMP7 MUC4

2.32e-041917043c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 RRAD

2.36e-04192704b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 ANGPT4 GAS1 MMP2

2.41e-04193704e27885a9e1a2a3e165c5366d4cfcda05c5454483
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

BICDL2 DBNDD1 MTCL1 MMP7

2.41e-041937049152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FNDC1 ANGPT4 GAS1 MMP2

2.46e-04194704c9e589fe7df6a9b377654581a2aebb607cbb03b9
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 SHANK2 LRRTM1 MMP2

2.46e-04194704735eee6ef25589f935fa922788ebbdbfef61249e
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 SBSN

2.46e-041947040e315c63407fa00643722a7d6138b1502f79b10d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 SBSN

2.46e-04194704588c45dafa00547b2506e298a2434b1b5e15560d
ToppCellP15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FNDC1 GAS1 MMP2 RRAD

2.46e-041947045f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 SBSN

2.46e-04194704c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 RRAD

2.51e-04195704d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 LRRTM1 RRAD

2.51e-041957044dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF9 RRAD DNAAF1 MUC4

2.51e-0419570479dc031258579ea328181dda33710dd897f1064a
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

FAT4 FNDC1 GAS1 MMP2

2.56e-041967047e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellAT1|World / shred by cell class for parenchyma

DBNDD1 MMP1 MMP7 SBSN

2.56e-041967042bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NPTX1 CELSR2 PKD1 RRAD

2.56e-04196704b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

FAT4 FNDC1 GAS1 MMP2

2.56e-0419670454aefcebf13704f51de84379e2e22ec0734b9461
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 MMP27 MMP1 MMP2

2.56e-041967041bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 NPTX1 MMP2 RRAD

2.61e-041977047d97c2d51a543c02d679e9257b22d0581e73a11d
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DBNDD1 GOLGA6D MMP7 MUC4

2.61e-04197704751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 GAS1 LRRTM1 SBSN

2.61e-0419770488a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 LRCH2 MMP2 SBSN

2.61e-041977040dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC1 GAS1 LRRTM1 SBSN

2.61e-041977042773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

BICDL2 KIF9 DNAAF1 MUC4

2.61e-04197704272c7f4e582ef57564450540242b0db766b78328
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FNDC1 NPTX1 MMP2 RRAD

2.61e-04197704671d6b5effbac2dd71d18f48d23c523738db1828
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

BICDL2 COL4A6 SLC38A10 MMP7

2.61e-041977041a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DBNDD1 GOLGA6D MMP7 MUC4

2.61e-041977042701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DBNDD1 GOLGA6D MMP7 MUC4

2.61e-0419770458d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD

2.66e-04198704637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A6 NPTX1 CMYA5 MUC4

2.66e-04198704de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD

2.66e-041987042d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

COL4A6 MMP1 MMP2 MMP7

2.66e-041987044235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 MMP1 MMP2 MMP8

2.66e-04198704447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAS1 MMP1 MMP2 SBSN

2.66e-04198704229588189825b1080181db9515185677b742c668
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A6 SHANK2 LRRTM1 MMP2

2.66e-041987044a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

FNDC1 PKD1 MMP2 SBSN

2.66e-041987049f9dcf23ffb333105263132d87b90095642294cf
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FNDC1 GAS1 CMYA5 SBSN

2.71e-041997048dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL4A6 FNDC1 MTCL1 RRAD

2.71e-04199704a207b4891881149d4c50721310690fd794157723
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF9 SHANK2 MMP7 DNAAF1

2.71e-0419970492fdf6e2f0786ab2ab78126e9131a93794168139
ToppCellBiopsy_Control_(H.)-Epithelial-KRT5-/KRT17+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DBNDD1 LRRTM1 MMP1 MMP7

2.71e-041997043b1f56c8b40bb36922a31d2d440a8c468a8aa3f1
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GAS1 MMP2 RRAD

2.71e-04199704edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MMP1 MMP7 CMYA5 MUC4

2.71e-04199704c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

COL4A6 CELSR2 MMP1 MMP7

2.76e-042007045cea84581201cee7ba8141b96e65864f4fd67113
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

FNDC1 ANGPT4 MTCL1 MMP2

2.76e-04200704593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT4 FNDC1 GAS1 MMP2

2.76e-0420070464d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FNDC1 ANGPT4 MTCL1 MMP2

2.76e-04200704dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellsevere-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC9A3 MMP28 MTRFR GNAS

2.76e-04200704f74bdabadca8ad6dae1b6e6812c66325aac50db0
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FAT4 FNDC1 GAS1 MMP2

2.76e-0420070476f3043cb88071256ff661885fe5a82a54f5b733
ComputationalGenes in the cancer module 211.

MMP1 MMP2 MMP7

6.60e-0611383MODULE_211
ComputationalMMPs.

MMP1 MMP2 MMP7

5.19e-0521383MODULE_562
ComputationalGenes in the cancer module 371.

MMP1 MMP2 MMP7

1.00e-0426383MODULE_371
ComputationalGenes in the cancer module 210.

MMP1 MMP2 MMP7

1.26e-0428383MODULE_210
ComputationalMetal ion (zinc) binding.

MMP1 MMP2 MMP7

5.22e-0445383MODULE_280
DrugDA-125

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.13e-1026676CID000114758
Drugmercuric acetate

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.90e-1030676CID000015337
Drugmalolactomycin D

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

4.41e-1032676CID006449115
DrugAC1L9M3B

MMP28 MMP27 MMP1 MMP2 GNAS MMP7 MMP8

5.33e-1061677CID000448562
Drug(1R,2R,4S,5R)-6-methylolcyclohexane-1,2,3,4,5-pentol

MMP1 MMP2 MMP7 MMP8

8.53e-099674CID011321479
DrugCGS 27023A

MMP1 MMP2 MMP7 MMP8

8.53e-099674ctd:C097658
Drugbenzoyl isothiocyanate

MMP1 MMP2 MMP8 NOS1

2.22e-0811674CID000068284
Drug5-mercapto-1,3,4-thiadiazole 13c

MMP1 MMP2 MMP8

2.44e-083673CID010030894
DrugHydroxamate 44

MMP1 MMP2 MMP8

2.44e-083673CID010027203
DrugHydroxamate 39

MMP1 MMP2 MMP8

2.44e-083673CID011036991
Drug(2S)-2-[(2-nitrobenzyl)-(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]propanehydroxamic acid

MMP1 MMP2 MMP8

2.44e-083673CID010994933
DrugHydroxamate 36

MMP1 MMP2 MMP8

2.44e-083673CID010500886
Drug5-mercapto-1,3,4-thiadiazole 13b

MMP1 MMP2 MMP8

2.44e-083673CID011757336
Drug4-aminophenyl

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

2.79e-0862676CID000181201
Drugdiacerein

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

3.08e-0863676CID000026248
Drugtitanium

SHANK2 MMP28 ACRV1 MMP27 MMP1 MMP2 MMP7 MMP8

3.67e-08170678CID000023963
DrugD 2163

MMP1 MMP2 MMP7 KCNH4

6.70e-0814674CID000148203
DrugAC1L1GXT

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

8.18e-0874676CID000003890
DrugA0395

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

8.87e-0875676CID009906466
DrugAC1NSU5S

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

8.87e-0875676CID005316299
Drugcarbamoylphosphonic acid

MMP1 MMP2 MMP8

9.72e-084673CID013879809
Drug3-hydroxypicolinic acid

MMP1 MMP2 MMP8

9.72e-084673ctd:C049246
Drug(2S)-2-[(2-nitrobenzyl)-(2,3,4,5,6-pentafluorophenyl)sulfonyl-amino]propanehydroxamic acid

MMP1 MMP2 MMP8

9.72e-084673CID011037999
Drugpirfenidone

COL4A6 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

1.66e-07138677CID000040632
Drugbeta-sulfone 7f

MMP1 MMP2 MMP8

2.43e-075673CID011526076
Drugalpha-sulfone 27e

MMP1 MMP2 MMP8

2.43e-075673CID011719408
DrugMMP-3 inhibitor

MMP1 MMP2 MMP8

2.43e-075673CID010549329
DrugHydroxamate 33

MMP1 MMP2 MMP8

2.43e-075673CID010810684
Drugbeta-sulfone 7e

MMP1 MMP2 MMP8

2.43e-075673CID011641261
Drugbeta-sulfone 7b

MMP1 MMP2 MMP8

2.43e-075673CID009867183
DrugHydroxamate 31

MMP1 MMP2 MMP8

2.43e-075673CID011799753
DrugHydroxysulfonamide 66

MMP1 MMP2 MMP8

2.43e-075673CID012635073
DrugCTS-1027

MMP1 MMP2 MMP8

2.43e-075673CID003342298
DrugCGS 25966

MMP1 MMP2 MMP8

2.43e-075673CID009821883
DrugSC-276

MMP1 MMP2 MMP8

2.43e-075673CID009802768
Drugalpha-sulfone 35g

MMP1 MMP2 MMP8

2.43e-075673CID011705502
DrugHydroxamate 34

MMP1 MMP2 MMP8

2.43e-075673CID010529602
Drugbeta-sulfone 7d

MMP1 MMP2 MMP8

2.43e-075673CID011548264
Drugalpha-sulfone 27d

MMP1 MMP2 MMP8

2.43e-075673CID011532911
Drugalpha-sulfone 27g

MMP1 MMP2 MMP8

2.43e-075673CID011561491
DrugI01-10485

MMP1 MMP2 MMP8

2.43e-075673CID011009332
Drugalpha-sulfone 27b

MMP1 MMP2 MMP8

2.43e-075673CID011697282
Drugbeta-sulfone 7c

MMP1 MMP2 MMP8

2.43e-075673CID011613649
DrugHydroxamate 32

MMP1 MMP2 MMP8

4.84e-076673CID010671441
DrugHydroxamate 26

MMP1 MMP2 MMP8

4.84e-076673CID010833334
DrugNSC47818

MMP1 MMP2 MMP8

4.84e-076673CID000240910
DrugHydroxysulfonamide 69

MMP1 MMP2 MMP8

4.84e-076673CID010610114
DrugNSC-139458

MMP1 MMP2 MMP8

4.84e-076673CID000283995
Drug4-aminoproline

MMP1 MMP2 MMP7

4.84e-076673CID000124558
DrugHydroxamate 35

MMP1 MMP2 MMP8

4.84e-076673CID010456675
Drug2-Amino-5-mercapto-1,3,4-thiadiazole

MMP1 MMP2 MMP8

4.84e-076673CID002723847
DrugHydroxamate 28

MMP1 MMP2 MMP8

4.84e-076673CID010792025
DrugHydroxamate 12

MMP1 MMP2 MMP8

4.84e-076673CID010594000
Drug(2S)-2-[benzyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]-N-hydroxy-3-methylbutanamide

MMP1 MMP2 MMP8

4.84e-076673CID010694926
DrugHydroxamate 10

MMP1 MMP2 MMP8

4.84e-076673CID010837740
DrugHydroxamate 29

MMP1 MMP2 MMP8

4.84e-076673CID010766622
DrugHydroxamate 8

MMP1 MMP2 MMP8

4.84e-076673CID010758013
DrugHydroxamate 14

MMP1 MMP2 MMP8

4.84e-076673CID010042482
Drug(2S)-2-[benzyl(1,1,2,2,3,3,4,4,4-nonafluorobutylsulfonyl)amino]-N-hydroxy-3-methylbutanamide

MMP1 MMP2 MMP8

4.84e-076673CID010696860
Druganti-TIMP-4

MMP1 MMP2 MMP7

8.45e-077673CID004283518
Drughydroxamate 20

MMP1 MMP2 MMP8

8.45e-077673CID011792968
DrugCGS 27023A Analog 51

MMP1 MMP2 MMP8

8.45e-077673CID010594938
DrugAC1L1DD6

COL4A6 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

9.65e-07179677CID000002299
DrugRo 32-3555

MMP1 MMP2 MMP8

1.35e-068673CID000193987
DrugSc 40827

MMP1 MMP2 MMP8

1.35e-068673CID000127918
Drughydroxamate 11

MMP1 MMP2 MMP8

1.35e-068673CID010001582
DrugMarimastat

MMP1 MMP2 MMP8

1.35e-068673DB00786
DrugDilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A

FAT4 LARP4B ABCA2 CELSR2 ACRV1 BCR ARHGAP45

1.54e-061926777364_UP
Druglosartan

COL4A6 SLC9A3 MMP28 MMP27 MMP1 MMP2 MMP7 MMP8 NOS1

1.59e-06378679CID000003961
DrugPicrotoxinin [17617-45-7]; Up 200; 13.6uM; PC3; HT_HG-U133A

LARP4B SLC9A3 PAK5 ACRV1 GAS1 MUC4 TRIM3

1.65e-061946774260_UP
Drugmarimastat

MMP1 MMP2 MMP7 MMP8 KCNH4

1.71e-0668675CID000119031
DrugAC1NRBJE

MMP28 SRC MMP1 MMP2 MMP7 MMP8

5.72e-06152676CID005288446
Drugisoflavone

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

6.40e-06155676CID000072304
DrugFN-439

MMP1 MMP2 MMP8

6.82e-0613673CID000004648
DrugN-methylmesoporphyrin

MMP1 MMP2 MMP7 MMP8

7.05e-0642674CID000444708
Drugquinacrine

MMP28 MMP27 MMP1 MMP2 GNAS MMP7 MMP8

7.30e-06243677CID000000237
Drugcarvedilol

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8

7.96e-06161676CID000002585
Drug(3S)-2-[4-(4-tert-butylphenyl)benzyl]-1,1-diketo-thiazinane-3-carbohydroxamic acid

MMP1 MMP2

8.53e-062672CID010112621
DrugMETHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID

MMP1 MMP8

8.53e-062672DB08403
DrugAgeladine A

MMP1 MMP2 MMP8

8.66e-0614673ctd:C482289
Drugglycylvaline

MMP1 MMP2 MMP7 MMP8

1.02e-0546674CID000097417
Drug1-((1-O-octadecyl-2-O-methylglycero)phospho)-3-deoxy-myo-inositol

SRC MMP1 MMP2

1.08e-0515673ctd:C435044
Drugperoxynitrite

MMP28 SRC MMP27 MMP1 MMP2 MMP7 MMP8 NOS1

1.35e-05373678CID000104806
DrugMelphalan

BICDL2 FAT4 SHANK2 GAS1 PLEKHA2 MTCL1 RRAD

1.67e-05276677ctd:D008558
Drugdioxane

MMP28 MMP27 MMP1 MMP2 MMP7 MMP8 BCR

1.75e-05278677CID000031275
DrugMMI270

MMP1 MMP2 MMP8

1.93e-0518673CID000446504
Drugglycyl-L-leucine

MMP1 MMP2 MMP7 MMP8

1.94e-0554674CID000092843
Drugaldosterone

SLC9A3 MMP28 PKD1 MMP27 MMP1 MMP2 MMP7 MMP8

2.12e-05397678CID000005839
Druggeldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A

ZNF787 DBNDD1 PRR5 MTCL1 DNAAF1 BCR

2.23e-051936761653_DN
DrugHlnl

MMP1 MMP2 MMP8

2.28e-0519673CID000122155
DrugPz-plgpa

MMP1 MMP2 MMP8

2.28e-0519673CID000152296
Drug17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A

SHANK2 ANGPT4 GAS1 DNAAF1 NOS1 TRIM3

2.36e-051956766172_UP
DrugBergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A

ABCA2 SLC9A3 SHANK2 SRC ZNF205 DNAAF1

2.43e-051966762726_UP
DrugMerbromin [129-16-8]; Up 200; 5uM; PC3; HT_HG-U133A

LARP4B ACRV1 GNAS RRAD DNAAF1 TRIM3

2.43e-051966763700_UP
Drug3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A

ANGPT4 ACRV1 PLEKHA2 LHX3 GNAS TRIM3

2.50e-051976766402_UP
DrugNatamycin [7681-93-8]; Up 200; 6uM; PC3; HT_HG-U133A

SPHK2 SHANK2 DBNDD1 GAS1 GNAS BCR

2.50e-051976765809_UP
Drugalpha-sulfone 27a

MMP1 MMP2

2.55e-053672CID009912853
DrugAC1L1JRO

MMP2 MMP8

2.55e-053672CID000005176
Drugdelta-(3,4-dihydroxyphenyl)-gamma-valerolactone

MMP1 MMP2

2.55e-053672CID000152432
Drugalpha-sulfone 13

MMP1 MMP2

2.55e-053672CID011616500
Diseaseimmunoglobulin light chain amyloidosis (is_marker_for)

MMP1 MMP2

1.43e-053652DOID:0080933 (is_marker_for)
Diseasecarotid artery disease (is_implicated_in)

MMP1 MMP2 MMP8

1.52e-0522653DOID:3407 (is_implicated_in)
Diseaseosteoarthritis (is_marker_for)

MMP1 MMP2 MMP8

6.35e-0535653DOID:8398 (is_marker_for)
Diseasestromelysin-2 measurement

MMP27 MMP8

7.13e-056652EFO_0802095
Diseasestanniocalcin-1 measurement

LARP4B CELSR2

1.33e-048652EFO_0020753
Diseasecystic fibrosis, lung disease severity measurement

SLC9A3 MUC4

1.70e-049652EFO_0007744, MONDO_0009061
Diseasehypertension (implicated_via_orthology)

SLC9A3 SRC MMP7 NOS1

1.86e-04128654DOID:10763 (implicated_via_orthology)
Diseaseabdominal aortic aneurysm (is_marker_for)

MMP2 MMP8

2.13e-0410652DOID:7693 (is_marker_for)
Diseaseage of onset of depressive disorder, wellbeing measurement

CMYA5 ARHGAP45

2.13e-0410652EFO_0007869, OBA_2040166
Diseaseintracranial aneurysm (is_implicated_in)

PKD1 MMP2

3.11e-0412652DOID:10941 (is_implicated_in)
Diseasepsoriasis

SPHK2 BBS7 PAK5 KPRP IFNLR1

3.43e-04273655EFO_0000676
Diseasecholangiocarcinoma (biomarker_via_orthology)

MMP2 MUC4

3.67e-0413652DOID:4947 (biomarker_via_orthology)
DiseaseCOVID-19 (is_marker_for)

MMP1 MMP2 MMP8

3.69e-0463653DOID:0080600 (is_marker_for)
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD1 DNAAF1

4.27e-0414652DOID:898 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (is_marker_for)

MMP1 MMP8

4.27e-0414652DOID:14004 (is_marker_for)
Diseasecholesteatoma of middle ear (is_marker_for)

MMP1 MMP2

5.62e-0416652DOID:10964 (is_marker_for)
DiseaseOral Submucous Fibrosis

MMP1 MMP2

7.15e-0418652C0029172
DiseaseNeoplasm Invasiveness

SRC MMP1 MMP2 SLC39A10

7.36e-04184654C0027626
Diseaserenovascular hypertension (biomarker_via_orthology)

SLC9A3 NOS1

7.98e-0419652DOID:1591 (biomarker_via_orthology)
Diseasepancreatic cancer (is_marker_for)

MMP2 GNAS MUC4

1.46e-03101653DOID:1793 (is_marker_for)
Diseasecongestive heart failure (biomarker_via_orthology)

MMP2 MMP8 NOS1

1.72e-03107653DOID:6000 (biomarker_via_orthology)
DiseaseEarly Pregnancy Loss

COL4A6 MMP7 MUC4

1.81e-03109653C3830362
DiseaseMiscarriage

COL4A6 MMP7 MUC4

1.81e-03109653C4552766
DiseaseSpontaneous abortion

COL4A6 MMP7 MUC4

1.81e-03109653C0000786
DiseaseAbortion, Tubal

COL4A6 MMP7 MUC4

1.81e-03109653C0000822
Diseaseceramide measurement

SPHK2 MDN1 CELSR2 ARHGAP45

1.82e-03235654EFO_0010222
Diseaseamyotrophic lateral sclerosis (is_marker_for)

MMP1 MMP2

1.87e-0329652DOID:332 (is_marker_for)
Diseasearteriosclerosis (is_implicated_in)

MMP1 MMP2

2.13e-0331652DOID:2349 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
HNGNGGDSGEDLLFG

BBS7

196

Q8IWZ6
GDIFGAENGAPGEQG

COL4A6

751

Q14031
GQIWPNDGEGAFHGD

BCR

411

P11274
AEGNTGDAFGIFPDG

FAT4

1036

Q6V0I7
GVGHDFPFTINNGTG

CELSR2

546

Q9HCU4
DAESQQGGGGNPFHR

DNAJC3

466

Q13217
GEHGSGEQPSGEQAS

ACRV1

146

P26436
GEAGDSGKPGAAFHQ

ADAT1

266

Q9BUB4
APGTGVGGDSHFDDD

MMP2

196

P08253
PGQGIGGDAHFDAEE

MMP8

186

P22894
VQGGHQADGPDHDSD

MTCL1

1081

Q9Y4B5
DGTQGGSGENLAPYH

NPTX1

331

Q15818
FGGVEDGPEAEAAGH

RRAD

111

P55042
GASSHGPGHAEENGF

PAK5

111

Q9P286
GPGLGGDTHFDEDEN

MMP27

186

Q9H306
DHEDGGGQETFNATG

MUC4

4776

Q99102
APGTGLGGDAHFDED

MMP7

181

P09237
DEEGGENGPADQGFQ

MDN1

4991

Q9NU22
GDGDEDGPAQQLSGF

ARHGAP45

1086

Q92619
GQEHQAPGHSEAGGV

IFNLR1

351

Q8IU57
GIDGLGDSDGQQNGH

GRXCR1

51

A8MXD5
DGGEGQHDGTFEPAT

LRRTM1

396

Q86UE6
NGDGDQGHENAALPD

LARP4B

101

Q92615
GTGIPFGESNGNDVH

KLHDC10

171

Q6PID8
LGPQGGRGDSNHENS

KCNH4

141

Q9UQ05
GNFSLEHGGLAGPEQ

LHX3

291

Q9UBR4
PEGSAEGGGVHQQAG

GOLGA2P5

106

Q9HBQ8
LAQHGGGDAPGAAAA

GAS1

76

P54826
VDGHLVGEPEGQNFG

KIF9

466

Q9HAQ2
GGGHSPGDSQYQELA

GOLGA6B

61

A6NDN3
GNGPQHAYDDGQEAG

NOS1

156

P29475
QVQDSFHEDGSGGEP

NPAS4

786

Q8IUM7
EQQDAGDFPEAGGGG

KCNA6

21

P17658
AALGVPAQGTGDNGH

DBNDD1

21

Q9H9R9
DGENNGHGEVASFPG

CRTC3

196

Q6UUV7
QQVESPTGAGAGGDH

FNDC1

1111

Q4ZHG4
GSHGNEVGNASPEVN

CMYA5

3356

Q8N3K9
HLGGEQSQAGAPEGS

REXO1L1P

31

Q8IX06
GGGHSPGDSQYQELA

GOLGA6C

61

A6NDK9
NGFNGEGGEEDPQAA

GNAS

66

P63092
AEGPASGEGHAGNLA

ABCA2

1346

Q9BZC7
QGFGDPAGEHWLGNE

ANGPT4

351

Q9Y264
HSLDDGDQGQGADAP

BICDL2

301

A1A5D9
GDNGSGGHFAHPRED

DNAAF1

66

Q8NEP3
GGGHSPGDSQYQELA

GOLGA6D

61

P0CG33
FPERRGQDGHGDQGN

KPRP

551

Q5T749
GQDGHGDQGNAFAGV

KPRP

556

Q5T749
GDGDNEEHGFCPVGQ

SLC39A10

786

Q9ULF5
PGVHEAGKEAGQFGQ

SBSN

446

Q6UWP8
AGDTGQPAEDSDHGG

SLC38A10

636

Q9HBR0
KNHGPDSGIGSDNGE

LRCH2

341

Q5VUJ6
QAGHGLGPEEDGFSL

PKD1

3441

P98161
FQGDHNDGLGNAFDG

MMP28

186

Q9H239
VHTPISQNGGDGQEG

PLEKHA2

156

Q9HB19
AENVHGAGGGAFPAS

SRC

21

P12931
GLVHAAGPGQDSGSQ

CCDC51

271

Q96ER9
GDHRDNSPFDGPGGN

MMP1

166

P03956
NPVQEHEAEGAAAGG

PRR5

261

P85299
LHVNGFNGEGGEEDP

GNAS

706

Q5JWF2
EPGGAHGESGGFQVV

SLC9A3

31

P48764
AEGDPQGQGLHDGSF

PREX1

1036

Q8TCU6
HFVGGAEASAPGEAG

SHANK2

1156

Q9UPX8
GEHAGGQEFGLEGSA

APOBR

801

Q0VD83
EGETQFGFPNAAGNH

ZXDB

771

P98169
EEQFVKGHGPGGQAT

MTRFR

61

Q9H3J6
ALAGAVNQHGGFEPA

SPHK2

281

Q9NRA0
ANTPEQADGGGSNGF

TTBK2

521

Q6IQ55
AGTFGGLQGDSAHEP

REM2

131

Q8IYK8
GLFPGEGQQAASHSG

TET3

1491

O43151
PHSEGASQEDGAQGA

ZNF205

56

O95201
SHGEGNGQFNAPTGV

TRIM3

661

O75382
AQHGDGLGAAGGEEP

ZNF787

301

Q6DD87