Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncarbohydrate binding

NOMO2 NOMO3 VCAN RPEL1 NOMO1

6.40e-05310285GO:0030246
GeneOntologyMolecularFunctionribonucleoprotein complex binding

CKAP5 NOMO2 NOMO3 NOMO1

1.86e-04206284GO:0043021
GeneOntologyMolecularFunctionribosome binding

NOMO2 NOMO3 NOMO1

6.21e-04120283GO:0043022
GeneOntologyMolecularFunctionmetallocarboxypeptidase activity

CPZ CPM

8.60e-0431282GO:0004181
GeneOntologyMolecularFunctionprotein tyrosine kinase activator activity

NRG3 ALK

1.16e-0336282GO:0030296
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH6 MYH7

1.29e-0338282GO:0000146
GeneOntologyMolecularFunctioncarboxypeptidase activity

CPZ CPM

2.14e-0349282GO:0004180
GeneOntologyMolecularFunctionNADP binding

DUOX1 CBR3

3.40e-0362282GO:0050661
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

MET ALK

3.73e-0365282GO:0004714
GeneOntologyMolecularFunctioncalmodulin binding

MYH6 MYH7 RGS1

4.00e-03230283GO:0005516
GeneOntologyMolecularFunctionmetalloexopeptidase activity

CPZ CPM

4.32e-0370282GO:0008235
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

MET ALK

6.30e-0385282GO:0019199
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

DUOX1 CBR3

7.81e-0395282GO:0016651
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO2 NOMO3 NOMO1

1.87e-079283GO:0160063
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO2 NOMO3 NOMO1

9.82e-0631283GO:0045048
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NOMO3 NOMO1

3.72e-057282GO:1900108
GeneOntologyBiologicalProcessprotein insertion into membrane

NOMO2 NOMO3 NOMO1

4.21e-0550283GO:0051205
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

NOMO3 NOMO1

6.36e-059282GO:1900107
GeneOntologyBiologicalProcessdetermination of left/right asymmetry in lateral mesoderm

NOMO3 NOMO1

7.94e-0510282GO:0003140
GeneOntologyBiologicalProcessmuscle filament sliding

MYH6 MYH7

1.85e-0415282GO:0030049
GeneOntologyBiologicalProcessadult heart development

MYH6 MYH7

2.68e-0418282GO:0007512
GeneOntologyBiologicalProcessactin-myosin filament sliding

MYH6 MYH7

2.68e-0418282GO:0033275
GeneOntologyBiologicalProcesslateral mesoderm development

NOMO3 NOMO1

3.33e-0420282GO:0048368
GeneOntologyBiologicalProcessnegative regulation of activin receptor signaling pathway

NOMO3 NOMO1

3.67e-0421282GO:0032926
GeneOntologyBiologicalProcessendoplasmic reticulum organization

NOMO2 NOMO3 NOMO1

4.05e-04107283GO:0007029
GeneOntologyBiologicalProcessnodal signaling pathway

NOMO3 NOMO1

5.66e-0426282GO:0038092
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO2 NOMO3 NOMO1

1.80e-079283GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO2 NOMO3 NOMO1

7.76e-0714283GO:0072379
GeneOntologyCellularComponentmuscle myosin complex

MYH6 MYH7

2.05e-0416282GO:0005859
GeneOntologyCellularComponentmyosin filament

MYH6 MYH7

5.09e-0425282GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH6 MYH7

6.40e-0428282GO:0016460
MousePhenoembryonic lethality during organogenesis, complete penetrance

MET MYH6 MYH7 ATP2C1 COLGALT1 MED23 PALB2 VCAN

4.32e-06700218MP:0011098
MousePhenoembryonic lethality during organogenesis

MET MYH6 MYH7 ATP2C1 COLGALT1 MED23 PALB2 VCAN

2.25e-05876218MP:0006207
DomainCarboxyPept_regulatory_dom

CPZ CPM NOMO2 NOMO3 NOMO1

6.63e-1213285IPR014766
Domain-

CPZ CPM NOMO2 NOMO3 NOMO1

6.63e-12132852.60.40.1120
DomainCarboxyPept-like_regulatory

CPZ CPM NOMO2 NOMO3 NOMO1

3.17e-1117285IPR008969
DomainDUF2012

NOMO2 NOMO3 NOMO1

1.21e-084283PF09430
DomainDUF2012

NOMO2 NOMO3 NOMO1

1.21e-084283IPR019008
DomainCarb-bd-like_fold

NOMO2 NOMO3 NOMO1

1.68e-078283IPR013784
DomainMyosin_N

MYH6 MYH7

2.25e-0415282IPR004009
DomainMyosin_N

MYH6 MYH7

2.25e-0415282PF02736
DomainZn_pept

CPZ CPM

3.27e-0418282SM00631
DomainMyosin_tail_1

MYH6 MYH7

3.27e-0418282PF01576
DomainMyosin_tail

MYH6 MYH7

3.27e-0418282IPR002928
DomainCARBOXYPEPT_ZN_2

CPZ CPM

3.65e-0419282PS00133
DomainMyosin-like_IQ_dom

MYH6 MYH7

3.65e-0419282IPR027401
Domain-

MYH6 MYH7

3.65e-04192824.10.270.10
Domain-

MET NOMO2 NOMO3 VCAN BTN1A1 NOMO1

3.78e-046632862.60.40.10
DomainCARBOXYPEPT_ZN_1

CPZ CPM

4.05e-0420282PS00132
DomainIg-like_fold

MET NOMO2 NOMO3 VCAN BTN1A1 NOMO1

5.28e-04706286IPR013783
DomainPeptidase_M14

CPZ CPM

5.38e-0423282PF00246
DomainPeptidase_M14

CPZ CPM

5.38e-0423282IPR000834
DomainMYOSIN_MOTOR

MYH6 MYH7

1.47e-0338282PS51456
DomainMyosin_head

MYH6 MYH7

1.47e-0338282PF00063
DomainMyosin_head_motor_dom

MYH6 MYH7

1.47e-0338282IPR001609
DomainMYSc

MYH6 MYH7

1.47e-0338282SM00242
DomainIQ

MYH6 MYH7

6.53e-0381282SM00015
DomainTyrKc

MET ALK

7.66e-0388282SM00219
DomainTyr_kinase_cat_dom

MET ALK

7.66e-0388282IPR020635
DomainIQ_motif_EF-hand-BS

MYH6 MYH7

8.00e-0390282IPR000048
DomainIQ

MYH6 MYH7

8.52e-0393282PS50096
DomainPROTEIN_KINASE_TYR

MET ALK

9.24e-0397282PS00109
DomainTyr_kinase_AS

MET ALK

9.24e-0397282IPR008266
DomainEGF

NRG3 VCAN

1.52e-02126282PF00008
DomainPkinase_Tyr

MET ALK

1.59e-02129282PF07714
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO2 NOMO3 NOMO1

4.67e-10328336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO2 NOMO3 NOMO1

4.67e-10328325576386
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO2 NOMO3 NOMO1

1.87e-09428331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO2 NOMO3 NOMO1

1.87e-0942839267806
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO2 NOMO3 NOMO1

2.61e-08828315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO2 NOMO3 NOMO1

3.91e-08928336261522
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO2 NOMO3 NOMO1

7.68e-081128332820719
Pubmed

Thymosin beta 4 is dispensable for murine cardiac development and function.

TMSB10 MYH6 MYH7

3.78e-071828322158707
Pubmed

High MET receptor expression but not gene amplification in ALK 2p23 rearrangement positive non-small-cell lung cancer.

MET ALK

6.25e-07228224722154
Pubmed

All-atom molecular dynamics simulations of actin-myosin interactions: a comparative study of cardiac α myosin, β myosin, and fast skeletal muscle myosin.

MYH6 MYH7

6.25e-07228224224850
Pubmed

Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart.

MYH6 MYH7

6.25e-07228217575272
Pubmed

Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression.

MYH6 MYH7

6.25e-07228221526716
Pubmed

Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium.

MYH6 MYH7

6.25e-07228216088376
Pubmed

Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.

MYH6 MYH7

6.25e-07228218480046
Pubmed

Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.

MYH6 MYH7

6.25e-0722821776652
Pubmed

Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.

MYH6 MYH7

6.25e-0722829884344
Pubmed

Dual potent c-Met and ALK inhibitors: from common feature pharmacophore modeling to structure based virtual screening.

MET ALK

6.25e-07228232126881
Pubmed

Murine pulmonary myocardium: developmental analysis of cardiac gene expression.

MYH6 MYH7

6.25e-0722827919499
Pubmed

Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes.

MYH6 MYH7

6.25e-07228212750067
Pubmed

Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.

MYH6 MYH7

6.25e-0722829541509
Pubmed

Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.

MYH6 MYH7

6.25e-07228223580644
Pubmed

Long-Read Sequence Confirmed a Large Deletion Including MYH6 and MYH7 in an Infant of Atrial Septal Defect and Atrial Arrhythmias.

MYH6 MYH7

6.25e-07228234384224
Pubmed

Characterization of human cardiac myosin heavy chain genes.

MYH6 MYH7

6.25e-0722822726733
Pubmed

Crizotinib in advanced non-small-cell lung cancer with concomitant ALK rearrangement and c-Met overexpression.

MET ALK

6.25e-07228230477470
Pubmed

Impact of Pre-Analytical Conditions on the Antigenicity of Lung Markers: ALK and MET.

MET ALK

6.25e-07228230724750
Pubmed

Human cardiac myosin heavy chain gene mapped within chromosome region 14q11.2----q13.

MYH6 MYH7

6.25e-0722822494889
Pubmed

Human cardiac myosin heavy chain genes and their linkage in the genome.

MYH6 MYH7

6.25e-0722823037493
Pubmed

β-myosin heavy chain is induced by pressure overload in a minor subpopulation of smaller mouse cardiac myocytes.

MYH6 MYH7

6.25e-07228221778428
Pubmed

Structural organization of the human cardiac alpha-myosin heavy chain gene (MYH6).

MYH6 MYH7

6.25e-0722828307559
Pubmed

β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.

MYH6 MYH7

6.25e-07228224829265
Pubmed

Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.

MYH6 MYH7

6.25e-0722822036722
Pubmed

Expression and clinical relevance of MET and ALK in Ewing sarcomas.

MET ALK

6.25e-07228223335077
Pubmed

Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector.

MYH6 MYH7

6.25e-07228225937279
Pubmed

Absence of ALK and MET alterations in head and neck sarcomatoid carcinoma.

MET ALK

6.25e-07228227262592
Pubmed

Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue.

MYH6 MYH7

6.25e-07228215621050
Pubmed

Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium.

MYH6 MYH7

6.25e-0722822969919
Pubmed

Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus.

MYH6 MYH7

1.87e-0632828620598
Pubmed

Mutation in myosin heavy chain 6 causes atrial septal defect.

MYH6 MYH7

1.87e-06328215735645
Pubmed

Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.

MYH6 MYH7

1.87e-06328218362229
Pubmed

Lung adenocarcinoma patient refractory to gefitinib and responsive to crizotinib, with concurrent rare mutation of the epidermal growth factor receptor (L861Q) and increased ALK/MET/ROS1 gene copy number.

MET ALK

1.87e-06328224389444
Pubmed

Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.

MYH6 MYH7

1.87e-0632821939265
Pubmed

Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.

MYH6 MYH7

1.87e-06328220923879
Pubmed

Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.

MYH6 MYH7

1.87e-0632821694848
Pubmed

FISH patterns of ROS1, MET, and ALK with a correlation of ALK immunohistochemistry in lung cancer: a case for introducing ALK immunohistochemistry 'Equivocal' interpretation category in the Ventana anti-ALK (D5F3) CDx assay - A tertiary cancer center experience.

MET ALK

1.87e-06328233402590
Pubmed

Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer.

MET ALK

1.87e-06328227136744
Pubmed

The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.

MYH6 MYH7

1.87e-06328222966157
Pubmed

Conotruncal anomalies in the trisomy 16 mouse: an immunohistochemical analysis with emphasis on the involvement of the neural crest.

MYH6 MYH7

1.87e-06328211066038
Pubmed

Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.

MYH6 MYH7

1.87e-06328218755891
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

NOMO2 NOMO3 NOMO1

2.07e-063128319136429
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

NOMO2 NOMO3 NOMO1

2.51e-063328330783098
Pubmed

Lung adenocarcinoma harboring concomitant SPTBN1-ALK fusion, c-Met overexpression, and HER-2 amplification with inherent resistance to crizotinib, chemotherapy, and radiotherapy.

MET ALK

3.75e-06428227496196
Pubmed

Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients.

MET ALK

3.75e-06428224200637
Pubmed

Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family.

MYH6 MYH7

3.75e-0642829927321
Pubmed

Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth.

MYH6 MYH7

3.75e-06428225900833
Pubmed

Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.

MYH6 MYH7

3.75e-06428211815426
Pubmed

Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages.

MYH6 MYH7

3.75e-06428228806941
Pubmed

EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma.

MET ALK

3.75e-06428231711449
Pubmed

Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.

MYH6 MYH7

3.75e-0642828482409
Pubmed

Murine cardiac progenitor cells require visceral embryonic endoderm and primitive streak for terminal differentiation.

MYH6 MYH7

3.75e-0642829389458
Pubmed

Single-stranded DNA-binding proteins PURalpha and PURbeta bind to a purine-rich negative regulatory element of the alpha-myosin heavy chain gene and control transcriptional and translational regulation of the gene expression. Implications in the repression of alpha-myosin heavy chain during heart failure.

MYH6 MYH7

6.24e-06528212933792
Pubmed

Analysis of EGFR, EML4-ALK, KRAS, and c-MET mutations in Chinese lung adenocarcinoma patients.

MET ALK

6.24e-06528223919423
Pubmed

Developmental regulation of myosin gene expression in mouse cardiac muscle.

MYH6 MYH7

6.24e-0652822277065
Pubmed

Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice.

MET ALK

6.24e-06528226581482
Pubmed

Mitochondrial fusion directs cardiomyocyte differentiation via calcineurin and Notch signaling.

MYH6 MYH7

6.24e-06528224091702
Pubmed

Recruitment of intra- and extracardiac cells into the myocardial lineage during mouse development.

MYH6 MYH7

6.24e-06528212629673
Pubmed

Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis.

MYH6 MYH7

6.24e-0652822552320
Pubmed

Enhancer of polycomb1, a novel homeodomain only protein-binding partner, induces skeletal muscle differentiation.

MYH6 MYH7

6.24e-06528217192267
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

CKAP5 MET COLGALT1 NOMO2 NOMO3 NOMO1

7.92e-0661328622268729
Pubmed

Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts.

MYH6 MYH7

9.36e-06628228381556
Pubmed

Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin.

MYH6 MYH7

1.31e-0572829004034
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH6 MYH7

1.31e-05728216819597
Pubmed

Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.

MYH6 MYH7

1.31e-05728221126233
Pubmed

Novel roles of cardiac-derived erythropoietin in cardiac development and function.

MYH6 MYH7

1.31e-05728238382296
Pubmed

A threshold of GATA4 and GATA6 expression is required for cardiovascular development.

MYH6 MYH7

1.74e-05828216847256
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH6 MYH7

1.74e-0582823864153
Pubmed

Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development.

MYH6 MYH7

1.74e-05828222553207
Pubmed

A long noncoding RNA protects the heart from pathological hypertrophy.

MYH6 MYH7

1.74e-05828225119045
Pubmed

Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.

MYH6 MYH7

1.74e-05828228659827
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

NOMO2 NOMO3 NOMO1

1.80e-056328331266804
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

PRR12 NOMO2 CBR3 NOMO3 NOMO1

2.07e-0542528524999758
Pubmed

Molecular characterization of the ventricular conduction system in the developing mouse heart: topographical correlation in normal and congenitally malformed hearts.

MYH6 MYH7

2.24e-05928211164852
Pubmed

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality.

MYH6 MYH7

2.24e-05928226487682
Pubmed

Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification.

MYH6 MYH7

2.80e-051028227052172
Pubmed

Suppression of atrial myosin gene expression occurs independently in the left and right ventricles of the developing mouse heart.

MYH6 MYH7

2.80e-051028210679931
Pubmed

Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival.

MYH6 MYH7

3.42e-051128231286143
Pubmed

Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.

MYH6 MYH7

3.42e-051128216374517
Pubmed

The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons.

MYH6 MYH7

3.42e-051128220739404
Pubmed

The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart.

MYH6 MYH7

3.42e-051128224137001
Pubmed

Heart defects in connexin43-deficient mice.

MYH6 MYH7

3.42e-05112829486664
Pubmed

TACE is required for fetal murine cardiac development and modeling.

MYH6 MYH7

4.10e-051228214499647
Pubmed

Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality.

MYH6 MYH7

4.10e-051228215169892
Pubmed

Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart.

MYH6 MYH7

4.10e-051228217482496
Pubmed

Jumonji, a nuclear protein that is necessary for normal heart development.

MYH6 MYH7

4.10e-051228210807864
Pubmed

Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.

MYH6 MYH7

4.10e-05122828424456
Pubmed

Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.

MYH6 MYH7

4.85e-051328221447557
Pubmed

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.

MYH6 MYH7

4.85e-051328234838591
Pubmed

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

MYH6 MYH7

4.85e-05132827628699
Pubmed

Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy.

MYH6 MYH7

4.85e-051328211950896
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

NOMO2 NOMO3 NOMO1

5.24e-059028315616553
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

NOMO2 NOMO3 NOMO1

5.59e-059228310493829
Cytoband14q12

MYH6 MYH7

5.22e-045528214q12
GeneFamilyMyosin heavy chains

MYH6 MYH7

8.67e-05151721098
GeneFamilyCarboxypeptidases

CPZ CPM

1.73e-04211721321
GeneFamilyReceptor Tyrosine Kinases|CD molecules

MET ALK

6.36e-0440172321
GeneFamilyAdenosine receptors|V-set domain containing

VCAN BTN1A1

1.01e-02163172590
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MET CPM NRG3 VCAN

3.25e-061642841cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM NRG3

3.93e-061722840c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM NRG3

3.93e-06172284eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellTCGA-Kidney-Primary_Tumor|TCGA-Kidney / Sample_Type by Project: Shred V9

MET TMSB10 COLGALT1 RGS1

5.83e-06190284773c4575d22483d89a54c8db0e09905deed0d088
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma|TCGA-Kidney / Sample_Type by Project: Shred V9

MET TMSB10 COLGALT1 RGS1

5.83e-06190284e3696e7542424c03d0a41136b10729a3dd09549a
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

MET NOMO2 NOMO3 NOMO1

5.95e-06191284ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM VCAN

6.20e-0619328480e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM VCAN

6.20e-06193284b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MET CPM NRG3 VCAN

6.20e-06193284ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM VCAN

6.20e-06193284263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM NRG3

6.46e-06195284938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM NRG3

6.46e-06195284d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellTransplant_Alveoli_and_parenchyma|World / Tissue, Lineage and Cell class of Lung Cells from 10X

TMSB10 CPM RGS1 VCAN

7.00e-0619928444bd36a62f06058c5d09feec6e96ecaf310f4791
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.08e-04148283d44f6c5fc8d1fce4046598030a48fa57ed520a6a
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|390C / Donor, Lineage, Cell class and subclass (all cells)

RAP1GAP2 AKNA MED23

1.12e-04150283fdbfc8f743cf848978cf0488493f6df60be53982
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAP1GAP2 MYH7 RGS1

1.19e-04153283c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MET MYH7 CBR3

1.26e-041562832cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.33e-0415928332d4c9f7ba6a96ce8443396b80568b41cbfc4927
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAB11FIP5 CPM VCAN

1.35e-041602836215ac6123a295f3c2f033786602a57b2e2e1177
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CPM TDRD9 RGS1

1.35e-04160283c2b5fadb4bac17fafc08831f6d3f4ff96ada7e70
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 TDRD9 RGS1

1.43e-04163283d18fee517e0daed51f89703f94f218567c83cb03
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 TDRD9 RGS1

1.43e-04163283f4a6e28ad3c1fcbf62ed9b2bf09f65d2ab0b31d1
ToppCellfacs-GAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 CPM RGS1

1.51e-04166283d22a08b415ef9e48398d69f3e45b04c33a085411
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

AKNA NOMO2 RGS1

1.54e-04167283abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMSB10 DUOX1 RGS1

1.56e-0416828307be11b6f0f37106e219692db5795c6dd32807c9
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB11FIP5 MYH6 RGS1

1.59e-04169283780fb0050852626062a729dd1b82b0cf61e7e9ca
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 CPM VCAN

1.59e-04169283563c267edaade0e5df192ad953801ef9768d4270
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MET MYH7 CPM

1.62e-041702836c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MET MYH7 CPM

1.62e-04170283d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKNA TMSB10 RGS1

1.65e-04171283834b39b48bf3135dc41e787f5e20ebb234b5d97a
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TDRD9 RGS1

1.65e-041712834198e7fef1aaee3d85722094f3e444655d393e9e
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPM RGS1 PALB2

1.68e-04172283ce444463f69bbb05c933615a0f1f43ddde3eee1c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPM RGS1 PALB2

1.68e-041722832c993a93ac91dcf6061eec001f51f8cccb6ee264
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 TDRD9 RGS1

1.68e-041722836c7d03393a60dab954054e34ea842cc77412eb19
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKNA TMSB10 RGS1

1.68e-04172283fdf54ab7ec002d831d8cce2ce5956d644176ca00
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TDRD9 RGS1

1.68e-04172283a3bcf0d432d8fccce50248e8d0c7a4804d69bfee
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TDRD9 RGS1

1.68e-04172283976d27edd5608616830624907fe050fcd3551865
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKNA TMSB10 RGS1

1.68e-04172283a749f4ab4048d806a83f1f71a197584b8db833ad
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBR3 PALB2 VCAN

1.71e-041732832b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBR3 PALB2 VCAN

1.71e-041732835086edc29c5a6137ca09877929a1317f9739c801
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MET MYH7 CPM

1.76e-041752838a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.76e-04175283ca2eabf03b70353e7eb15b6f622b2f9223a99e18
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

MET DUOX1 CBR3

1.79e-041762833fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRR12 RGS1 VCAN

1.79e-0417628391ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 CBR3 RGS1

1.79e-041762833c3b6c02d7acdc1305878ee34e9cbabbf9e87892
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 CBR3 RGS1

1.79e-041762837c743b7e954c1ebfa289ed529abacb88504112ea
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MET NRG3 NOMO2

1.79e-0417628352af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS1 VCAN BTN1A1

1.79e-04176283b99e20e4dd8b3322c9d7a08d518ed4f8f356b3de
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.85e-0417828393bd3205081b97e00e7a1bbaf4a311075b9cbfe8
ToppCellfacs-Lung-18m-Hematologic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKNA TMSB10 RGS1

1.89e-0417928362fd60963203a3db98c83b19292c40cc4421cd94
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MET NRG3 NOMO2

1.89e-041792838c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMSB10 CPM RGS1

1.89e-041792833d3716078afdb9a89ddfadb3197cd1b52fa770be
ToppCelldroplet-Kidney-nan-21m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.89e-0417928321736ae288ea6113e2a5604fbda338fc6b2b94a8
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMSB10 CPZ VCAN

1.92e-0418028312537d8a569faa69f474284d2c201475722b8ca1
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.95e-04181283e8a68214930a6d15c47207656601b2209e283aae
ToppCellfacs-Kidney-nan-24m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.98e-04182283e5f62ce9b9e0d28627617f7cbc81026f8442e402
ToppCellfacs-Kidney-nan-24m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

1.98e-041822830e16824c721d8b7d527157cb65feec909f6b974c
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.01e-0418328386c67f258fa25a818797df5d4df7f27b44cb5381
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NRG3 CBR3 ALK

2.01e-04183283e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET DUOX1 CPM

2.01e-041832836847c1252d6bb105524f812658112517fd351eab
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.04e-04184283f9365feed31e48f3382588bab077f99c5a3f5b04
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AKNA RGS1 PALB2

2.04e-0418428317ffa0e890960c00a3b5fa33d48caba66c61dbb0
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.04e-04184283290b8ef0bc4b7b99a2b35b96a756699d3f233b96
ToppCellfacs-SCAT-Fat-18m-Lymphocytic|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.04e-0418428343313b0b4e4d4b18dd67ac0c525d7aa4db493f71
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMSB10 CPM VCAN

2.04e-04184283bc0dfe29337f02594e7e0092c9e47dda94b45ad5
ToppCell390C-Myeloid-Monocyte-CD14+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

TMSB10 VCAN

2.07e-04342823ff1ad679da59252f0e3caec27f25d3f30984d7f
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CPM COLGALT1 VCAN

2.11e-041862838694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CPM COLGALT1 VCAN

2.11e-04186283f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

MET CPM VCAN

2.14e-04187283be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellHealthy/Control-CD4+_CTL|World / Disease group and Cell class

AKNA RAB11FIP5 RGS1

2.14e-04187283d54d3214d77a9469e94a16c00a80626fd4953e2b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MET DUOX1 CPM

2.14e-041872835df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellfacs-Kidney-nan-24m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.14e-04187283e4cb79c7aa29e8c99d5a3a209d2f9a03c2ba9bb7
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET MYH7 CPM

2.18e-041882833dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

TMSB10 CPM VCAN

2.18e-041882836740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET MYH7 CPM

2.18e-04188283b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET NRG3

2.21e-04189283aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RAP1GAP2 MET CPM

2.21e-041892837659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MET NRG3 VCAN

2.21e-0418928328b502611829e4a24caff2562545c7db97686099
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET NRG3

2.21e-041892838977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA TMSB10 RGS1

2.21e-0418928343d8264b763ef6c82368c1d67d63ff0a25861c45
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MET MYH7 CPM

2.25e-041902838ff8c586237cf15f930416710bcff45205fe6f70
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MET DUOX1 CPM

2.25e-0419028327a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

MET ETNPPL TDRD9

2.25e-041902833729648a17093b438398b82e32bbccc3af7b8c5d
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET MYH7 CPM

2.25e-04190283aaf5f1c1ff7b1454f4e5dacfeb48e1c3627e3372
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET MYH7 CPM

2.25e-04190283a20123d5c6cb8c2f0dfd99bbfdb571a73c36234d
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MET MYH7 CPM

2.28e-04191283f98fc372e579ce69409afbbe0f83c03c7ea62632
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MET MYH7 CPM

2.28e-0419128308b1d3b3be78bf7fd9e9039027e35275f2be88d0
ToppCellLA-05._Cytoplasmic_Cardiomyocyte_I|World / Chamber and Cluster_Paper

MET TMSB10 MYH6

2.28e-04191283d825e55278dce666c332cc060d1255659e07e568
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM

2.28e-041912839032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RAP1GAP2 MET CPM

2.28e-0419128360ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMSB10 RGS1 VCAN

2.28e-0419128351535232e889db52a9b24e5696b1687e93dd7302
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RAP1GAP2 MET CPM

2.28e-0419128305731ece7867659c662f952812805f947032fe10
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CPZ CPM VCAN

2.28e-04191283a05e9a7eb137d804570dd7d8905975d735738767
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MET MYH7 CPM

2.28e-04191283f896fb490c4a17adac5e00ed9b6e6145eab1e564
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET DUOX1 CPM

2.28e-04191283e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

MET DUOX1 CPM

2.28e-04191283a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MET MYH7 CPM

2.28e-04191283c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MET MYH7 CPM

2.28e-041912832f71f1fb6b5872d84860840b22e789a87ab14eec
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MET MYH7 CPM

2.28e-04191283210589095a3f5d5117174caf6ec110b502f27030
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP2 MET CPM

2.28e-041912835717809a1476c20f65bce722c5a57cff92ee0d7a
DiseaseCaveolinopathy

MYH6 MYH7

4.83e-064272cv:C5679790
DiseaseCardiomyopathy, Familial Hypertrophic, 1 (disorder)

MYH6 MYH7

4.83e-064272C3495498
DiseaseHypertrophic cardiomyopathy 1

MYH6 MYH7

4.83e-064272cv:C3495498
DiseaseCARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 1

MYH6 MYH7

4.83e-064272192600
DiseaseIdiopathic hypertrophic subaortic stenosis

MYH6 MYH7

1.69e-057272C0700053
DiseaseObstructive asymmetric septal hypertrophy

MYH6 MYH7

1.69e-057272C0597124
DiseaseCardiomyopathy, Hypertrophic, Familial

MYH6 MYH7

2.89e-059272C0949658
DiseaseMuscular dystrophy, limb-girdle, autosomal dominant

MYH6 MYH7

3.61e-0510272cv:C5675009
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0110454 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0111602 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:3429 (implicated_via_orthology)
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0111269 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0080719 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0080326 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH6 MYH7

3.61e-0510272DOID:0111596 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH6 MYH7

5.29e-0512272DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH6 MYH7

5.29e-0512272DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH6 MYH7

6.25e-0513272DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH6 MYH7

8.40e-0515272DOID:0050646 (implicated_via_orthology)
DiseasePrimary familial hypertrophic cardiomyopathy

MYH6 MYH7

1.84e-0422272cv:C0949658
DiseaseHypertrophic obstructive cardiomyopathy

MYH6 MYH7

2.39e-0425272C4551472
DiseaseLimb-girdle muscular dystrophy

MYH6 MYH7

2.59e-0426272cv:C0686353
DiseasePrimary familial dilated cardiomyopathy

MYH6 MYH7

3.45e-0430272cv:C0340427
Diseasemyocardial infarction (biomarker_via_orthology)

MYH6 MYH7 VCAN

4.16e-04160273DOID:5844 (biomarker_via_orthology)
DiseaseHeart Failure, Diastolic

MYH6 MYH7

4.18e-0433272C1135196
DiseasePrimary dilated cardiomyopathy

MYH6 MYH7

4.44e-0434272cv:C0007193
DiseaseFamilial dilated cardiomyopathy

MYH6 MYH7

7.45e-0444272C0340427
DiseaseNeuroblastoma

MET ALK

8.50e-0447272C0027819
DiseaseOsteosarcoma

MET RGS1

8.50e-0447272C0029463
DiseaseCardiomyopathy

MYH6 MYH7

8.50e-0447272cv:C0878544
DiseaseCardiomyopathy, Dilated

MYH6 MYH7

8.86e-0448272C0007193
Diseasemyopathy (implicated_via_orthology)

MYH6 MYH7

8.86e-0448272DOID:423 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PFMGKTEEEVFSGMK

VCAN

711

P13611
RENVMKKGFDPMTPE

BTN1A1

376

Q13410
FGEVFKMMQAEEAPK

ATP2C1

241

P98194
IKPPMCFTEEDAKFM

ETNPPL

411

Q8TBG4
FKPMMKEFRFEPSSQ

NOMO3

926

P69849
ISTPKLDKMPGMFFS

RGS1

6

Q08116
LDKMPGMFFSANPKE

RGS1

11

Q08116
SMFDLSMKDKPRSPF

RAB11FIP5

176

Q9BXF6
PPKFDKIEDMAMLTF

MYH7

81

P12883
VFMKGSPEEKSRLMF

DUOX1

846

Q9NRD9
EKMMESSFVGPQSFP

NRG3

441

P56975
FKPMMKEFRFEPSSQ

NOMO2

926

Q5JPE7
AFPGMFMDTPEDEKT

MED23

21

Q9ULK4
FKPMMKEFRFEPSSQ

NOMO1

926

Q15155
SEKPVEPFESKMFGE

PALB2

631

Q86YC2
PASKMFPFIMEGTKS

CKAP5

1321

Q14008
PQEEKMFSPTPDEKM

CPZ

396

Q66K79
MFSPTPDEKMFKLLS

CPZ

401

Q66K79
IMPSMNPDGFEAVKK

CPM

121

P14384
EEATEKMVSMKPPGF

AKNA

831

Q7Z591
KSDDPMPFDIKAEMT

CBR3

96

O75828
PTKTPDKMGFDEVFM

COLGALT1

331

Q8NBJ5
FKPFEKPVMISMGNE

MET

841

P08581
PPTMKSSEFFEMLEK

RAP1GAP2

51

Q684P5
MTDGSVPFPMKDDEK

TDRD9

1111

Q8NDG6
EEKQPEMKSGFMASF

PRR12

1271

Q9ULL5
PPKFDKIEDMAMLTF

MYH6

81

P13533
MPPEAFMEGIFTSKT

ALK

1296

Q9UM73
MTVEPGFGEQKFMED

RPEL1

141

Q2QD12
MADKPDMGEIASFDK

TMSB10

1

P63313