Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal middle ear development

HSPG2 LMNA

1.25e-052502MP:0014516
DomainLaminin_G_1

HSPG2 EYS

6.23e-0411642PF00054
DomainXK_rel

XKR8 XKRY

6.23e-0411642IPR018629
DomainXK-related

XKR8 XKRY

6.23e-0411642PF09815
DomainEGF_extracell

TENM4 ADAM33 STAB1

1.14e-0360643IPR013111
DomainEGF_2

TENM4 ADAM33 STAB1

1.14e-0360643PF07974
DomainEGF_3

HSPG2 EYS TENM4 ADAM33 STAB1

1.26e-03235645PS50026
DomainEGF

HSPG2 EYS TENM4 ADAM33 STAB1

1.26e-03235645SM00181
DomainEGF-like_dom

HSPG2 EYS TENM4 ADAM33 STAB1

1.63e-03249645IPR000742
DomainEGF_1

HSPG2 EYS TENM4 ADAM33 STAB1

1.80e-03255645PS00022
DomainEGF-like_CS

HSPG2 EYS TENM4 ADAM33 STAB1

2.00e-03261645IPR013032
DomainGrowth_fac_rcpt_

HSPG2 EYS ERBB4 STAB1

2.02e-03156644IPR009030
DomainEGF_2

HSPG2 EYS TENM4 ADAM33 STAB1

2.13e-03265645PS01186
DomainFN3

MYOM1 CRLF3 IGDCC3 IL6R

3.73e-03185644SM00060
Domainig

HSPG2 MYOM1 IGDCC3 IL6R

4.10e-03190644PF00047
DomainImmunoglobulin

HSPG2 MYOM1 IGDCC3 IL6R

4.10e-03190644IPR013151
DomainEGF_LAM_2

HSPG2 STAB1

4.73e-0330642PS50027
DomainEGF_LAM_1

HSPG2 STAB1

4.73e-0330642PS01248
DomainFN3

MYOM1 CRLF3 IGDCC3 IL6R

4.83e-03199644PS50853
DomainFN3_dom

MYOM1 CRLF3 IGDCC3 IL6R

5.73e-03209644IPR003961
DomainLaminin_EGF

HSPG2 STAB1

6.39e-0335642PF00053
DomainEGF_Lam

HSPG2 STAB1

6.39e-0335642SM00180
DomainLAM_G_DOMAIN

HSPG2 EYS

7.51e-0338642PS50025
DomainLaminin_EGF

HSPG2 STAB1

7.51e-0338642IPR002049
DomainLDLR_class-A_CS

HSPG2 TMPRSS2

8.29e-0340642IPR023415
DomainLaminin_G_2

HSPG2 EYS

8.29e-0340642PF02210
DomainEGF_CA

HSPG2 EYS STAB1

8.48e-03122643SM00179
DomainIGc2

HSPG2 MYOM1 IGDCC3 IL6R

8.61e-03235644SM00408
DomainIg_sub2

HSPG2 MYOM1 IGDCC3 IL6R

8.61e-03235644IPR003598
DomainEGF-like_Ca-bd_dom

HSPG2 EYS STAB1

8.86e-03124643IPR001881
DomainEGF

HSPG2 EYS STAB1

9.26e-03126643PF00008
DomainLamG

HSPG2 EYS

9.97e-0344642SM00282
Pubmed

Two patients with 'Dropped head syndrome' due to mutations in LMNA or SEPN1 genes.

LMNA SELENON

3.55e-06266215961312
Pubmed

α-Klotho mice demonstrate increased expression of the non-sulfated N-glycan form of the HNK-1 glyco-epitope in kidney tissue.

KL B3GAT1

3.55e-06266224723043
Pubmed

Molecular mechanism of rigid spine with muscular dystrophy type 1 caused by novel mutations of selenoprotein N gene.

LMNA SELENON

3.55e-06266216779558
Pubmed

Aging syndrome genes and premature coronary artery disease.

KL LMNA

3.55e-06266216262891
Pubmed

IL6R-STAT3-ADAR1 (P150) interplay promotes oncogenicity in multiple myeloma with 1q21 amplification.

ADAR IL6R

1.06e-05366231413087
Pubmed

Nuclear import mechanism of neurofibromin for localization on the spindle and function in chromosome congression.

LMNA CA5A

2.12e-05466226490262
Pubmed

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.

OR56A5 OR56A3 OR56A4

3.42e-053366317350283
Pubmed

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients.

COL4A5 ADAM33

5.29e-05666225840998
Pubmed

Combinatorial receptor codes for odors.

OR56A5 OR56A4

5.29e-05666210089886
Pubmed

Mice develop normally without tenascin.

COL4A5 HSPG2

9.86e-0586621383086
Pubmed

PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex.

RBBP7 ZNF516

1.58e-041066234180153
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A5 HSPG2

1.58e-04106629136074
Pubmed

Novel progerin-interactive partner proteins hnRNP E1, EGF, Mel 18, and UBC9 interact with lamin A/C.

LMNA UNC13D

1.58e-041066216248985
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A5 HSPG2

1.93e-04116627500359
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A5 HSPG2

2.31e-041266216024816
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A5 SERPINF2

3.18e-041466212878203
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A5 HSPG2

4.18e-041666215878328
Pubmed

Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

LMNA SELENON

4.74e-041766220301468
Pubmed

Human chromosome 11 DNA sequence and analysis including novel gene identification.

TENM4 OR56A5 UNC93B1

4.83e-048066316554811
Pubmed

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.

ADAR IL6R

6.59e-042066225340798
Pubmed

HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.

RNF123 UBE2J2 PEDS1

6.82e-049066335671810
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

THEMIS2 IARS2 NUP210L TAFA3 CTRC XKR8 SELENON IL6R

7.28e-04103166816710414
Pubmed

Genetic variation in healthy oldest-old.

KL LMNA

9.53e-042466219680556
Pubmed

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.

RBBP7 ZNF516

1.12e-032666225228645
Pubmed

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.

GPHN ERBB4

1.30e-032866224448406
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

COL4A5 HSPG2

1.39e-032966222613833
InteractionCA5A interactions

RNF123 LMNA CA5A

1.69e-068643int:CA5A
GeneFamilyOlfactory receptors, family 56

OR56A5 OR56A3 OR56A4

1.20e-069453167
GeneFamilyBlood group antigens|XK related family

XKR8 XKRY

3.28e-0411452955
GeneFamilyFucosyltransferases|Blood group antigens

FUT7 POFUT2

4.64e-0413452434
GeneFamilyFibronectin type III domain containing

MYOM1 CRLF3 IGDCC3

7.35e-03160453555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 MYOM1 IGDCC3

7.48e-03161453593
ToppCellnormal-na-Myeloid-conventional_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

TENM4 LMNA ACER3 UNC93B1 IL6R

8.12e-0618566567e881a89a491665b8c612fff084c202c0c79235
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMNA ACER3 UNC93B1 SERPINF2 IL6R

9.24e-061906654b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 HSPG2 MYOM1 LMNA ADAM33

1.05e-0519566556e7cd980f8fc2dae842e6a7bd919d4b41cebbbb
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 HSPG2 MYOM1 LMNA ADAM33

1.05e-05195665a28a504c69bc4dda7de023e1b4ea4f62390b158e
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THEMIS2 UNC93B1 CMAHP STAB1

4.17e-051306643a0846b74ba34bd0e2a05b4f1f39f3940df93780
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF ACER3 RTTN IGDCC3

5.27e-051386646b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THEMIS2 UNC93B1 CMAHP STAB1

6.91e-05148664d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

THEMIS2 EYS POP1 XKR8

8.48e-05156664735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCell368C-Myeloid-Dendritic-cDC1|368C / Donor, Lineage, Cell class and subclass (all cells)

CTRC UNC93B1 FUT7 SAMD14

8.91e-05158664c276a259e20ee704e2d04baf693e8d677f96f654
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 TENM4 ACP3 IGDCC3

9.13e-05159664c186bf05c61fac348cf41973827cced83fafd58a
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-Microglia_Siglech|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THEMIS2 UNC93B1 IL6R STAB1

9.35e-05160664c3f2f362e5d0602bb997e8367b4c9a8fe88e4ea8
ToppCellE12.5-Hematopoietic-Immune-immune_cell_unspecified|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THEMIS2 UNC93B1 IL6R STAB1

9.35e-051606645a4a5a50dfdf6af9406e4f685712f7fe390a02f3
ToppCellE12.5-Hematopoietic-Immune|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THEMIS2 UNC93B1 IL6R STAB1

9.35e-05160664cd59830a524c14a1f591c5c615b55510e4104e5b
ToppCellfrontal_cortex-Non-neuronal-macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THEMIS2 UNC93B1 IL6R STAB1

1.00e-04163664b89f586b444f90047c8ce407f53847fd1ee7cca3
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THEMIS2 UNC93B1 IL6R STAB1

1.00e-04163664cbe9b4c4b2e42e9f92a57ed66758af93434db5bb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHROOM4 ACER3 CTRC TMPRSS2

1.00e-04163664e4077e587895c85bc806be05ff5d451088e39468
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF123 LMNA ADAM33 SAMD14

1.03e-0416466418eeda51e69722992c3a7f699be293535a90868b
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

THEMIS2 POP1 SERPINF2 FUT7

1.05e-041656648b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

THEMIS2 POP1 SERPINF2 FUT7

1.05e-04165664243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 IL6R CA5A STAB1

1.08e-0416666483d0c26ccee605df6b04bbca31661bf4ff4f22ba
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

THEMIS2 ADAM33 CMAHP STAB1

1.08e-0416666476d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYOM1 NUP210L CAPS SELENON

1.13e-041686648f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC93B1 CMAHP IL6R STAB1

1.13e-041686648ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF123 LMNA ADAM33 SAMD14

1.13e-0416866408fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC93B1 CMAHP IL6R STAB1

1.13e-04168664c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC93B1 CMAHP IL6R STAB1

1.13e-04168664a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF123 LMNA ADAM33 SAMD14

1.13e-04168664d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MYOM1 UNC13D SAMD14 CA5A

1.15e-04169664d571e84e01e3316748d4407ed98881b17484e035
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

POP1 EME2 SAMD14 ADAR

1.21e-041716640d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RNF123 CAPS EME2 IL6R

1.24e-04172664a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 KL C1orf167 FUT7

1.29e-041746646b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RNF123 CAPS EME2 IL6R

1.32e-04175664f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 UNC93B1 ASTL IL6R

1.32e-04175664c9dc6aa652ac887470806a950311657c423d9495
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC93B1 CMAHP IL6R STAB1

1.32e-04175664a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCellPND07-Immune|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRLF3 UNC93B1 CMAHP IL6R

1.35e-041766642f87f49b64c6f89823d540172a8e923ebaa6d6cd
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCNF RNF123 FUT7 CMAHP

1.38e-04177664f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 HSPG2 TMPRSS2 UNC13D

1.38e-041776649af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 TENM4 ACP3 RTTN

1.41e-04178664dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-tDC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THEMIS2 ADAM33 UNC93B1 SERPINF2

1.47e-041806643d9f3e6f13e558279b4ef43e2c44c7c50d761745
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 EYS KL STAB1

1.47e-041806645861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 HSPG2 TMPRSS2 UNC13D

1.50e-04181664b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHROOM4 HSPG2 KL STAB1

1.57e-04183664a644258ba90acc62d571623e429d72ffc4b69203
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 HSPG2 TMPRSS2 UNC13D

1.60e-0418466442ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC5A10 TENM4 SERPINF2 IL6R

1.60e-041846649434731f651820b05335085582960f08fbf895de
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 LMNA ACP3 CAPS

1.63e-0418566474b787e225d83efcb84e79c23499febe1a106622
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|390C / Donor, Lineage, Cell class and subclass (all cells)

ANXA2R TTI2 CTRC SAMD14

1.67e-04186664064b6047215597465bb51a8a1547ef5a226552f9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 HSPG2 TMPRSS2 UNC13D

1.67e-041866643aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellControl-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ZNF516 ASTL SERPINF2 FUT7

1.67e-041866643de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

TENM4 ASTL SERPINF2 FUT7

1.67e-04186664b05c394aa3573ba855abc3066739ca193883b0c3
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A5 HSPG2 MYOM1 ADAM33

1.70e-04187664218c9b4f28499389c43005d9626af2ac01066027
ToppCelldroplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF RNF123 LMNA SAMD14

1.70e-0418766499724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A5 HSPG2 MYOM1 ADAM33

1.70e-04187664c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 HSPG2 MYOM1 ADAM33

1.74e-0418866461f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A5 HSPG2 MYOM1 ADAM33

1.74e-041886647553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TENM4 ZNF516 ASTL SERPINF2

1.74e-04188664d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ANXA2R TTI2 CTRC SAMD14

1.74e-041886642c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SHROOM4 MYOM1 FAM178B SAMD14

1.74e-04188664c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

THEMIS2 TENM4 LMNA ACER3

1.74e-04188664d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF RNF123 LMNA SAMD14

1.81e-041906644288189e3a499c395896c950598810b02f401685
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNF RNF123 LMNA SAMD14

1.85e-0419166408be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 EYS KL STAB1

1.85e-04191664e3fc5c92491b6e334abffbf085c00a0b5fa1aed2
ToppCelldroplet-Marrow-BM-1m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF123 LMNA ADAM33 SAMD14

1.85e-04191664d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMNA ACER3 SERPINF2 IL6R

1.88e-041926648e606eae3e5b07a856d3c2a74186d486da96309c
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMNA UNC93B1 SERPINF2 IL6R

1.92e-04193664984ea5b871479527ab57dd813bacae844c0d8c06
ToppCellsystemic_lupus_erythematosus-treated-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LMNA UNC93B1 SERPINF2 IL6R

1.92e-04193664529281b912070c8655e38880ac73f5e4bd6ee4ce
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 HSPG2 MYOM1 ADAM33

1.96e-04194664aaecde88bd54134a938e76cdf059c1c2653e4e77
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 CMAHP SELENON STAB1

2.04e-0419666495c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

LMNA ACP3 SERPINF2 IL6R

2.04e-04196664ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERBB4 LMNA ACP3 CAPS

2.04e-04196664d688350aadc622984d612ae6b2fd7c0113a4ec0f
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A5 HSPG2 MYOM1 ADAM33

2.04e-041966644740ef6e428f1ccc81fc98c3b868afd38ce60535
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

LMNA ACP3 SERPINF2 IL6R

2.04e-04196664aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMNA ACP3 UNC93B1 SERPINF2

2.08e-0419766422e4ffb5de483eaf78f14badf3d08db898e3b3dd
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LMNA ACP3 UNC93B1 SERPINF2

2.08e-04197664346974c6c5809a3fe88cbf067e2d64c340310a31
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TENM4 LMNA ADAM33 SAMD14

2.08e-04197664079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMNA ACP3 UNC93B1 SERPINF2

2.08e-041976641ae45c1ec3b3f88e0c1f99de58c58b1ec1b968ee
ToppCellCOVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease group, lineage and cell class

LMNA ACP3 UNC93B1 SERPINF2

2.08e-04197664843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LMNA ACP3 UNC93B1 SERPINF2

2.08e-04197664f78f44dcd7855c96f148678c1f416075aef71b4e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 UNC93B1 IL6R STAB1

2.12e-0419866488635244a0b306d2cc50b8412fe47bb359c9cf00
ToppCelldistal-Epithelial-Club-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TMPRSS2 ASTL SERPINF2 CMAHP

2.12e-0419866477c7fa7626ea35cb50de9c2f2df637d22e77d3fe
ToppCellmLN-(5)_Dendritic_cell-(54)_pDC|mLN / shred on region, Cell_type, and subtype

THEMIS2 OR56A4 SERPINF2 FUT7

2.16e-041996641e738219784a446ee8b0ddeb408e0050e1929e60
ToppCellmLN-Dendritic_cell-pDC|mLN / Region, Cell class and subclass

THEMIS2 OR56A4 SERPINF2 FUT7

2.16e-0419966454f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EYS FAM178B UNC93B1 FUT7

2.20e-042006646a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCellCOVID-19-COVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease, condition lineage and cell class

LMNA ACP3 UNC93B1 SERPINF2

2.20e-04200664e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THEMIS2 UNC13D UNC93B1 STAB1

2.20e-042006645f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ToppCellCOVID-19-COVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease, condition lineage and cell class

LMNA UNC93B1 SERPINF2 FUT7

2.20e-04200664b8f52e65813d331c49cdd5f354fdfec6fc8c339e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ACP3 XKR8 UNC93B1 IL6R

2.20e-042006645c638c80661017c85f9390f1b398ac7728c8f001
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LMNA ACER3 SERPINF2 IL6R

2.20e-042006644a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

ACP3 XKR8 UNC93B1 IL6R

2.20e-04200664604a88633d4162337e394155c7346dbdef8b9f5a
ToppCell(54)_pDC|World / shred on Cell_type and subtype

THEMIS2 OR56A4 SERPINF2 FUT7

2.33e-04203664b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)|Cerebellum / BrainAtlas - Mouse McCarroll V32

NUP210L TAFA3 CTRC

2.55e-048366346de51665a1502f3132f2d56c85e8ba365431b3d
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

NUP210L TAFA3 CTRC

2.55e-04836631ab841bab56a05dc0e7551a1408e5c5570f548e0
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pcp2_(Purkinje_Neurons)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

NUP210L TAFA3 CTRC

2.55e-04836637a38262bca74f0e26ac07d936753dc83fde3cb3d
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gm9946_(Gm9946)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAFA3 SLFN12 CA5A

2.64e-04846633804a8a4d371eb104da4cde23c2db3df942b44de
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gm9946_(Gm9946)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAFA3 SLFN12 CA5A

2.64e-04846637da70a68b28fc0414ac3ac7dcd6f6edb56a5e76d
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gm9946_(Gm9946)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAFA3 SLFN12 CA5A

2.64e-0484663e865b8507c27f226eb69ee6c051516f347f79712
Drugnaphthol-AS-BI

KL ACP3 CTRC SERPINF2

3.96e-0637664CID000071060
Diseaseinterleukin 6 receptor subunit alpha measurement

NUP210L ADAR IL6R

2.37e-0613613EFO_0008187
DiseaseFocal Segmental Glomerulosclerosis, Not Otherwise Specified

COL4A5 LMNA

1.50e-049612C4049702
Diseaseprogression free survival, urinary bladder cancer

ERBB4 TENM4

2.74e-0412612EFO_0004920, MONDO_0001187
Diseasehomostachydrine measurement

EYS ERBB4

3.23e-0413612EFO_0021164
DiseaseCongenital Fiber Type Disproportion

LMNA SELENON

6.30e-0418612C0546264
Diseasebipolar disorder, schizophrenia, response to lithium ion

FAM178B CMAHP

7.80e-0420612GO_0010226, MONDO_0004985, MONDO_0005090
DiseaseL lactate dehydrogenase measurement

TENM4 STAB1

1.32e-0326612EFO_0004808
DiseaseMental deterioration

ERBB4 TENM4

1.65e-0329612HP_0001268
Diseaseanterior uveitis

EYS IL6R

2.00e-0332612EFO_1000811

Protein segments in the cluster

PeptideGeneStartEntry
PWTLLITVWHQSTLA

B3GAT1

16

Q9P2W7
IHWQDIVRNPWPSNL

ERBB4

161

Q15303
VPPIIGITTQFHAWW

ACER3

206

Q9NUN7
AWVAPLSPQHQRAWL

C1orf167

671

Q5SNV9
WQLSKQSGWAHPSLP

CAPS

16

Q13938
NLSWDTLHPPLVWER

SERPINF2

316

P08697
LHPVWSQQHRTPRWA

GPR33

131

Q49SQ1
WAPLPHWRGTSLIQQ

CDRT15P3

131

P0DPF6
TPHWVLDGQPWRTVS

ADAM33

41

Q9BZ11
LRLQQLPWSSPLHPW

ANXA2R

116

Q3ZCQ2
ITPLWAPSVHIGQRW

ASTL

251

Q6HA08
PIINWRLNWGHIPSH

HSPG2

436

P98160
PTIHWSKLRSPLPWQ

HSPG2

3241

P98160
CILTWHHQEPLPWAQ

GPHN

676

Q9NQX3
PNFQSWQHWLSLPLS

OR56A4

21

Q8NGH8
HSPPTDLVWKAQNTW

LMNA

506

P02545
SLQLLWEPWPRLAQH

IGDCC3

536

Q8IVU1
AWQAQKAPTHIWQPL

MAGEL2

616

Q9UJ55
EWHPQPSSYVVNWTL

EYS

31

Q5T1H1
NALQHWPALQKWSLP

JMJD7

56

P0C870
RQEWSPWSVPQIGHS

CRLF3

256

Q8IUI8
PSIGLHWRSSLWPAQ

CSNKA2IP

101

A0A1B0GTH6
TITILVWHWPFTDQP

FUT7

46

Q11130
LPSWQVLSPVQPWQT

MS4A10

16

Q96PG2
PRWVTLLQDWHVILP

PEDS1

196

A5PLL7
ITTQEHLWLLLPSWP

MT-ND1

166

P03886
THALQWPSLTVQWLP

RBBP7

36

Q16576
PSFQSWQHWLSLPLS

OR56A5

21

P0C7T3
IWNPILLWQPIPVHT

ACP3

131

P15309
PSESRQLWIWLHPTL

POP1

321

Q99575
WQTSNNTLHPLWTVP

CA5A

41

P35218
PRWLSVTWQDPHSWN

IL6R

231

P08887
ARPHSWPWQISLQYL

CTRC

36

Q99895
TPPLWKIAVSTQAWN

ADAR

191

P55265
RLTHGQTQPWTTQLW

CCNF

461

P41002
IQIPHCPQGWDSLWI

COL4A5

1581

P29400
ITWLNSPSQVAVVPW

KL

836

Q9UEF7
TLTQISGPTHWVPWI

EME2

156

A4GXA9
QPPLAQSRLQHWLWS

NUP210L

1871

Q5VU65
HIPTQQGLAWLIPLW

RTTN

1361

Q86VV8
AWLWTHLTLAALQPP

TAFA3

21

Q7Z5A8
HWQSPDIHQVRIPWS

POFUT2

91

Q9Y2G5
LQWLFQLLTWPPETS

FAM178B

326

Q8IXR5
TLAVWVKWPIHPSAP

RHBDF1

521

Q96CC6
WRWSPEHNSQPLVAA

SHROOM4

726

Q9ULL8
PPVHHWTSQQVGQWL

SAMD14

321

Q8IZD0
FVRSPSWQHWLSLPL

OR56A3

21

Q8NH54
LVEQHGSDIWWTLPP

IARS2

556

Q9NSE4
WNHFQIKLPLTPPNW

CMAHP

451

Q9Y471
PTSQHRDWCPWVNIT

ZC3HC1

421

Q86WB0
IWHRVSCNSVAPPWI

ZNF516

781

Q92618
SALPGAWPWQVSLHV

TMPRSS2

261

O15393
FWAPVPRVLQHSWIL

UNC93B1

421

Q9H1C4
GTHLPSNTKIIPAWW

XKRY

96

O14609
PPPQSVQIENLTWWT

SLC5A10

536

A0PJK1
WTLQQVTRPWLSQHL

TTI2

231

Q6NXR4
EAGLQELIPTTWWPH

RNF123

446

Q5XPI4
ILHLPLSQKGPFWTW

THEMIS2

156

Q5TEJ8
QWCSHSSLQPQLPWL

SELENON

111

Q9NZV5
HPDTWNPAWSVSTIL

UBE2J2

101

Q8N2K1
WLTLHWPSNQPTQLV

GEMIN5

286

Q8TEQ6
RAPFITQEHTLWLPW

TENM4

976

Q6N022
TSLPAPHSWPLLEWQ

SLFN12

361

Q8IYM2
WTSPPLHSLGLRSVW

STAB1

1916

Q9NY15
PQQAVPWSAWVTRHG

TMEM239

61

Q8WW34
HRWFQPAIPSWLQKT

UNC13D

586

Q70J99
LQKLISLHPFNPWNW

ZHX1-C8orf76

121

Q96EF9
HSSWLPSGIPLQLWL

XKR8

306

Q9H6D3
NGVPLSPSKWVQTLW

MYOM1

446

P52179