Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH14 DNAH1 DYNC1H1

2.42e-06181094GO:0008569
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 MYO9A MYO10 DNAH14 DNAH1 MYH15 DYNC1H1

3.81e-061181097GO:0003774
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

TUBB8 SPTB SPTBN1 ARPC2 TUBB6 TUBB8B MYBPC3

7.24e-061301097GO:0005200
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH14 DNAH1 DYNC1H1

1.55e-05281094GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH14 DNAH1 DYNC1H1

4.83e-05371094GO:0045505
GeneOntologyMolecularFunctionactin filament binding

MYO9A MYO10 SPTB SPTBN1 COTL1 ARPC2 MYH15

2.50e-042271097GO:0051015
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ATP6V1B2 MYO9A MYO10 ATP6V1E2 ABCC9 YTHDC2 DNAH14 DNAH1 MYH15 DYNC1H1

5.34e-0461410911GO:0140657
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DNAH14 DNAH1 DYNC1H1

5.84e-04701094GO:0003777
GeneOntologyCellularComponentdynein complex

DNHD1 DNAH14 DNAH1 DYNC1H1

1.75e-04541084GO:0030286
GeneOntologyCellularComponentsupramolecular fiber

MYO9A TUBB8 SPTBN1 STYXL2 ABCC9 COTL1 DNAH14 PGM1 DNAH1 ARPC2 TUBB6 TEKT2 MYH15 TUBB8B DYNC1H1 MYBPC3

3.58e-04117910816GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYO9A TUBB8 SPTBN1 STYXL2 ABCC9 COTL1 DNAH14 PGM1 DNAH1 ARPC2 TUBB6 TEKT2 MYH15 TUBB8B DYNC1H1 MYBPC3

3.85e-04118710816GO:0099081
HumanPhenoOligodontia

ATP6V1B2 TRIO WNT10B CHSY1 BCL11B PIK3C2A

1.44e-0565436HP:0000677
DomainDynein_HC_stalk

DNHD1 DNAH14 DNAH1 DYNC1H1

1.05e-06141094IPR024743
DomainMT

DNHD1 DNAH14 DNAH1 DYNC1H1

1.05e-06141094PF12777
DomainDHC_fam

DNHD1 DNAH14 DNAH1 DYNC1H1

1.43e-06151094IPR026983
DomainDynein_heavy

DNHD1 DNAH14 DNAH1 DYNC1H1

1.43e-06151094PF03028
DomainDynein_heavy_dom

DNHD1 DNAH14 DNAH1 DYNC1H1

1.43e-06151094IPR004273
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH1 DYNC1H1

6.72e-05141093IPR024317
DomainDynein_heavy_dom-2

DNHD1 DNAH1 DYNC1H1

6.72e-05141093IPR013602
DomainDHC_N2

DNHD1 DNAH1 DYNC1H1

6.72e-05141093PF08393
DomainAAA_8

DNAH14 DNAH1 DYNC1H1

6.72e-05141093PF12780
DomainPP2A_PR55_CS

PPP2R2B PPP2R2C

2.01e-0441092IPR018067
DomainSpectrin_bsu

SPTB SPTBN1

2.01e-0441092IPR016343
DomainPP2A_PR55

PPP2R2B PPP2R2C

2.01e-0441092IPR000009
DomainPR55_2

PPP2R2B PPP2R2C

2.01e-0441092PS01025
DomainPR55_1

PPP2R2B PPP2R2C

2.01e-0441092PS01024
DomainSpectrin

TRIO SPTB SPTBN1

3.15e-04231093PF00435
DomainTRP_2

TRPC7 TRPC3

4.99e-0461092PF08344
DomainTRP_dom

TRPC7 TRPC3

4.99e-0461092IPR013555
DomainPeptidase_Metallo

MMP27 MMP24 TLL2

6.33e-04291093IPR006026
DomainZnMc

MMP27 MMP24 TLL2

6.33e-04291093SM00235
DomainSpectrin_repeat

TRIO SPTB SPTBN1

6.33e-04291093IPR002017
DomainTRPC_channel

TRPC7 TRPC3

6.95e-0471092IPR002153
DomainSPEC

TRIO SPTB SPTBN1

8.48e-04321093SM00150
DomainSpectrin/alpha-actinin

TRIO SPTB SPTBN1

8.48e-04321093IPR018159
DomainP-loop_NTPase

DNHD1 ATP6V1B2 MYO9A MYO10 ABCC9 YTHDC2 DNAH14 DNAH1 HS6ST1 MYH15 GNAT1 SULT4A1 DYNC1H1

1.32e-0384810913IPR027417
DomainMyosin_head_motor_dom

MYO9A MYO10 MYH15

1.41e-03381093IPR001609
DomainMYOSIN_MOTOR

MYO9A MYO10 MYH15

1.41e-03381093PS51456
DomainMyosin_head

MYO9A MYO10 MYH15

1.41e-03381093PF00063
DomainMYSc

MYO9A MYO10 MYH15

1.41e-03381093SM00242
DomainBeta-tubulin_BS

TUBB8 TUBB6

1.47e-03101092IPR013838
DomainBeta_tubulin

TUBB8 TUBB6

1.47e-03101092IPR002453
DomainTRP_channel

TRPC7 TRPC3

1.79e-03111092IPR004729
DomainTUBULIN_B_AUTOREG

TUBB8 TUBB6

1.79e-03111092PS00228
PathwayREACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT

TUBB8 SPTB SPTBN1 TUBB6 TUBB8B DYNC1H1

5.02e-05102916M27648
PathwayWP_GLYCOGEN_METABOLISM

PGM1 PHKG1 PPP2R2B PPP2R2C

6.50e-0534914MM15985
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

TRPC7 RPS6KA4 TRIO MYO10 TUBB8 TRPC3 SPTB SPTBN1 ARPC2 SEMA3A TUBB6 TUBB8B RPL13

7.79e-055759113M29853
PathwayWP_GLYCOGEN_SYNTHESIS_AND_DEGRADATION

PGM1 PHKG1 PPP2R2B PPP2R2C

1.24e-0440914M39595
PathwayREACTOME_L1CAM_INTERACTIONS

RPS6KA4 TUBB8 SPTB SPTBN1 TUBB6 TUBB8B

1.30e-04121916M872
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC7 TRIO MYO10 TRPC3

1.81e-0444914M875
PathwayREACTOME_AGGREPHAGY

TUBB8 TUBB6 TUBB8B DYNC1H1

1.81e-0444914M29830
PathwayREACTOME_HCMV_EARLY_EVENTS

RANBP2 TUBB8 TUBB6 TRIM28 TUBB8B DYNC1H1

2.66e-04138916M29805
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

RPS6KA4 TUBB8 TUBB6 TUBB8B

2.76e-0449914M891
PathwayREACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE

TUBB8 TUBB6 TUBB8B

3.18e-0421913M27067
PathwayREACTOME_COPI_INDEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

TUBB8 TUBB6 TUBB8B DYNC1H1

3.74e-0453914M27651
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

TUBB8 TUBB6 TUBB8B DYNC1H1

4.94e-0457914M27251
PathwayREACTOME_ER_TO_GOLGI_ANTEROGRADE_TRANSPORT

TUBB8 SPTB SPTBN1 TUBB6 TUBB8B DYNC1H1

5.12e-04156916M27097
PathwayWP_GLUCURONIDATION

UGT1A8 UGT1A9 PGM1

5.40e-0425913MM15820
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC7 TRPC3 DGKK

5.40e-0425913MM14511
PathwayWP_GLUCURONIDATION

UGT1A8 UGT1A9 PGM1

6.08e-0426913M39404
PathwayREACTOME_HCMV_INFECTION

RANBP2 TUBB8 TUBB6 TRIM28 TUBB8B DYNC1H1

6.25e-04162916M29804
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC7 TRPC3 DGKK

6.80e-0427913M12123
PathwayKEGG_PENTOSE_PHOSPHATE_PATHWAY

PFKP TKTL2 PGM1

6.80e-0427913M1386
PathwayREACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS

TUBB8 TUBB6 TUBB8B

8.42e-0429913M27948
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RANBP2 MYO9A POLR2B SPTBN1 WDR70 PFKP NDUFA9 TRRAP COTL1 CDC45 TUBB6 GTF3C1 TCERG1 PIK3C2A TRIM28 RBM19 SLC25A1 CPSF1 UTP20 TANC1 GCN1 DYNC1H1 RPL13

3.52e-1113531102329467282
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 RANBP2 TRIO POLR2B SPTBN1 LARP1 YTHDC2 MDH2 ARPC2 CDC45 GTF3C1 TCERG1 TRIM28 RBM19 CPSF1 UTP20 GCN1 DYNC1H1 SOAT1 RPL13

2.03e-0814251102030948266
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ATP6V1B2 RANBP2 POLR2B YTHDC2 PFKP MDH2 TRRAP ARPC2 TUBB6 GTF3C1 TRIM28 CPSF1 UTP20 GCN1 DYNC1H1 RPL13 XPO7

2.43e-0810241101724711643
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

RANBP2 MYO9A POLR2B TRRAP GTF3C1 TRIM28 SLC25A1 GCN1 DYNC1H1

2.57e-08211110917314511
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 RTL6 TRIO MYO10 WDR70 CHSY1 GTF2IRD1 TRRAP TBC1D9 RHPN1 TRIM28 RBM19 CPSF1 TANC1 GCN1 ABTB2 DYNC1H1

7.27e-0811051101735748872
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ATP6V1B2 RANBP2 POLR2B SPTBN1 LARP1 PFKP MDH2 DNAH1 ARPC2 TUBB6 PIK3C2A TRIM28 SLC25A1 CPSF1 PCBD1 GCN1 DYNC1H1 RPL13

7.48e-0812471101827684187
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPS6KA4 POLR2B SPTBN1 LARP1 YTHDC2 PFKP NDUFA9 ARPC2 TUBB6 GTF3C1 TCERG1 TRIM28 RBM19 SLC25A1 CPSF1 UTP20 DYNC1H1 RPL13

8.42e-0812571101836526897
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1B2 TRIO MYO9A SPTB SPTBN1 LARP1 YTHDC2 PFKP MDH2 NDUFA9 COTL1 PGM1 ARPC2 PPP2R2C TRIM28 TANC1 UNC13A DYNC1H1 RPL13

1.14e-0714311101937142655
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DNHD1 ATP6V1B2 TUBB8 SPTBN1 AASDHPPT MDH2 COTL1 ITGB8 PGM1 ARPC2 TUBB6 MMP24 PIK3C2A SLC25A1 PCBD1 DYNC1H1

1.34e-0710161101619056867
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

PFKP TUBB6 GTF3C1 TRIM28 GCN1 OBI1 DYNC1H1

1.53e-07125110721654808
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

RANBP2 ACACB TUBB8 WDR70 TUBB6 PPP2R2C TRIM28 GCN1 DYNC1H1 RPL13

2.16e-073571101037059091
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RANBP2 POLR2B SPTBN1 USP9Y GTF2IRD1 TRRAP GTF3C1 TCERG1 TRIM28 SLC25A1 CPSF1 GCN1 UNC13A DYNC1H1 HCRTR1 RPL13

3.11e-0710821101638697112
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

RANBP2 POLR2B YTHDC2 PFKP TRRAP ARPC2 TUBB6 GTF3C1 TRIM28 SLC25A1 UTP20 GCN1 DYNC1H1

3.76e-077041101329955894
Pubmed

Myosin-X recruits lamellipodin to filopodia tips.

TRIO MYO10 COTL1 ARPC2 PIK3C2A GCN1

4.09e-0789110636861887
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RANBP2 POLR2B LARP1 AASDHPPT PFKP NDUFA9 CDC45 TUBB6 GTF3C1 TCERG1 TRIM28 SLC25A1 CPSF1 PCBD1 GCN1 DYNC1H1 RPL13

4.46e-0712571101737317656
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

ATP6V1B2 RANBP2 POLR2B LARP1 NDUFA9 ARPC2 TUBB6 TRIM28 GCN1 DYNC1H1

5.09e-073921101033144569
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

POLR2B MDH2 TCERG1 TRIM28 SLC25A1 GCN1 DYNC1H1 RPL13

5.50e-07221110829991511
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RANBP2 POLR2B SPTBN1 LARP1 PFKP MDH2 COTL1 PGM1 TUBB6 GTF3C1 TCERG1 TRIM28 GCN1 OBI1 DYNC1H1 RPL13

6.88e-0711491101635446349
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

RANBP2 POLR2B LARP1 PFKP GTF3C1 CPSF1 GCN1 DYNC1H1

9.31e-07237110829564676
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RANBP2 SPTBN1 LARP1 YTHDC2 PFKP GTF2IRD1 TRRAP TBC1D9 CCNYL1 GTF3C1 TRIM28 CPSF1 UTP20

1.09e-067741101315302935
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 SPTBN1 LARP1 YTHDC2 PFKP TRRAP GTF3C1 CPSF1 UTP20 GCN1 DYNC1H1 XPO7

1.14e-066531101222586326
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

RANBP2 SPTBN1 PFKP TUBB6 GTF3C1 TCERG1 TRIM28 GCN1 DYNC1H1

1.18e-06332110932786267
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RPS6KA4 MYO10 POLR2B SPTBN1 LARP1 PFKP ARPC2 TCERG1 TRIM28 SLC25A1 CPSF1 UTP20 DYNC1H1 RPL13

1.87e-069491101436574265
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

RANBP2 POLR2B SPTBN1 LARP1 YTHDC2 PFKP BCL11B GTF3C1 TCERG1 TRIM28 SLC25A1

2.55e-065831101129844126
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

ATP6V1B2 SPTBN1 PFKP MDH2 NDUFA9 TUBB6 TCERG1 TRIM28 SLC25A1 GCN1 DYNC1H1 RPL13

2.60e-067071101219738201
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RANBP2 TUBB8 SPTBN1 PFKP TRRAP GTF3C1 GCN1 DYNC1H1

2.60e-06272110831010829
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RANBP2 TUBB8 POLR2B SPTBN1 LARP1 YTHDC2 PFKP MDH2 NDUFA9 ARPC2 TUBB6 GTF3C1 PIK3C2A TRIM28 GCN1 DYNC1H1 SOAT1

2.84e-0614401101730833792
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

RANBP2 TUBB8 WDR70 LARP1 CHSY1 TRRAP GTF3C1 TCERG1 UTP20 OBI1 DYNC1H1 FOXD4 XPO7

3.32e-068571101325609649
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

ATP6V1B2 SPTB SPTBN1 ABCC9 PFKP MDH2 NDUFA9 TRRAP TEKT2 GNAT1 DYNC1H1

4.65e-066211101122794259
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

ATP6V1B2 SPTB SPTBN1 PFKP MDH2 NDUFA9 ARPC2 DYNC1H1 RPL13

5.71e-06403110930562941
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

RANBP2 TUBB8 LARP1 PFKP TUBB6 GTF3C1 TRIM28 SLC25A1 UTP20 GCN1 RPL13

7.68e-066551101135819319
Pubmed

Nucleolar proteome dynamics.

MDH2 ARPC2 TCERG1 TRIM28 RBM19 UTP20 GCN1 DYNC1H1 RPL13

7.80e-06419110915635413
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

RANBP2 SPTBN1 PEX3 ARFGEF1 NDUFA9 TBC1D9 TRIM28 SLC25A1 GCN1 SOAT1 XPO7

7.90e-066571101136180527
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

RANBP2 MDH2 NDUFA9 PGM1 ARPC2 SLC25A1 GCN1 DYNC1H1 SOAT1

8.25e-06422110927342126
Pubmed

Melanopsin signalling in mammalian iris and retina.

TRPC7 TRPC3 GNAT1

8.60e-0613110322051675
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

NDUFA9 TRRAP CDC45 GTF3C1 SLC25A1 DYNC1H1

8.62e-06150110630154076
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RANBP2 TUBB8 POLR2B SPTBN1 LARP1 PFKP MDH2 NDUFA9 TUBB6 TCERG1 TRIM28 RBM19 SLC25A1 GCN1 DYNC1H1 RPL13

9.84e-0614151101628515276
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

SPTBN1 LARP1 PFKP MDH2 NDUFA9 DNAH1 ARPC2 TUBB6 TRIM28 SLC25A1 GCN1 DYNC1H1

9.89e-068071101230575818
Pubmed

Involvement of TRPC3 channels in calcium oscillations mediated by OX(1) orexin receptors.

TRPC3 HCRTR1

9.91e-062110219464259
Pubmed

Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage.

BCL11B TRIM28

9.91e-062110233514850
Pubmed

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

UGT1A8 UGT1A9

9.91e-062110218568343
Pubmed

Neuronal migration defects in the Loa dynein mutant mouse.

DNAH1 DYNC1H1

9.91e-062110221612657
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

RANBP2 MYO10 SPTBN1 TUBB6 TRIM28 GCN1 DYNC1H1

1.04e-05235110728378594
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

RANBP2 ACACB POLR2B ITGB8 TUBB6 TRIM28 RPL13

1.32e-05244110730349055
Pubmed

TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.

RANBP2 POLR2B TRIM28

1.36e-0515110332900933
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

SPTBN1 MDH2 TRRAP ARPC2 TCERG1 GCN1 DYNC1H1 XPO7

1.44e-05344110830333137
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

RANBP2 YTHDC2 TRRAP TUBB6 GTF3C1 TCERG1 RBM19

1.55e-05250110733536335
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

MYO10 SPTBN1 LARP1 NDUFA9 ARPC2 TUBB6 CCNYL1 SLC25A1 DYNC1H1 RPL13

1.62e-055801101035676659
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RANBP2 MYO10 PFKP TRIM28 CPSF1

1.63e-0599110527746211
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

DET1 MYO10 POLR2B WNT10B PFKP TRRAP MAD2L1BP CDC45 TRIM28 SLC25A1 CPSF1 GCN1 OBI1 SOAT1 RPL13

1.92e-0513271101532694731
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

POLR2B LARP1 USP9Y CDC45 TUBB6 GTF3C1 TRIM28 SLC25A1 GCN1 DYNC1H1 RPL13

1.97e-057251101127025967
Pubmed

KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.

SPTBN1 MDH2 TUBB6 GCN1 DYNC1H1

2.07e-05104110536055981
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

RANBP2 SPTBN1 LARP1 MDH2 TUBB6 TRIM28 GCN1 DYNC1H1 RPL13

2.17e-05477110931300519
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

RANBP2 YTHDC2 TUBB6 GTF3C1 TRIM28 RBM19 UTP20 DYNC1H1 RPL13

2.40e-05483110936912080
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

GTF2IRD1 TRRAP GTF3C1

2.43e-0518110317846119
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

RANBP2 YTHDC2 PFKP CDC45 MYH15 RPL13

2.58e-05182110632239614
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

POLR2B SPTBN1 AASDHPPT PFKP NDUFA9 CDC45 TUBB6 TRIM28 SLC25A1 GCN1

2.60e-056131101022268729
Pubmed

PEX14 is required for microtubule-based peroxisome motility in human cells.

TUBB8 PEX3 TUBB6 DYNC1H1

2.65e-0554110421525035
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

TUBB8 SPTBN1 ARFGEF1 LARP1 PFKP MDH2 TUBB6 TRIM28 GCN1

2.86e-05494110926831064
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTB SPTBN1

2.97e-053110211294830
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A8 UGT1A9

2.97e-053110229519853
Pubmed

Genetic polymorphisms of UGT1A8, UGT1A9 and HNF-1α and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid.

UGT1A8 UGT1A9

2.97e-053110223721685
Pubmed

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

UGT1A8 UGT1A9

2.97e-053110226247833
Pubmed

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.

UGT1A8 UGT1A9

2.97e-053110217339869
Pubmed

Systematic dissection of dynein regulators in mitosis.

DNAH1 DYNC1H1

2.97e-053110223589491
Pubmed

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.

TRPC7 TRPC3

2.97e-053110228526717
Pubmed

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.

UGT1A8 UGT1A9

2.97e-053110219225446
Pubmed

Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells.

TRPC7 TRPC3

2.97e-053110215972814
Pubmed

Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling.

MRAP2 HCRTR1

2.97e-053110228939058
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTB SPTBN1

2.97e-05311028479293
Pubmed

Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.

PPP2R2B PPP2R2C

2.97e-05311029514514
Pubmed

Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

UGT1A8 UGT1A9

2.97e-053110216397224
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A8 UGT1A9

2.97e-053110212847094
Pubmed

A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.

TRPC7 TRPC3

2.97e-053110219812035
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTB SPTBN1

2.97e-053110232425157
Pubmed

Developmental expression of brain beta-spectrin isoform messenger RNAs.

SPTB SPTBN1

2.97e-05311021467942
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

HTR2B ACACB POLR2B SPTBN1 YTHDC2 USP9Y TRRAP GTF3C1 CPSF1

3.00e-05497110936774506
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNHD1 TUBB8 SPTB TRRAP TUBB6 RPL13

3.00e-05187110626460568
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ATP6V1B2 RANBP2 TRIO POLR2B SPTBN1 LARP1 TBC1D9 ARPC2 TUBB6 CPSF1 PCBD1 OBI1

3.65e-059221101227609421
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

TUBB8 SPTBN1 MDH2 TUBB6 TUBB8B DYNC1H1 RPL13

3.82e-05288110731501420
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

POLR2B TRRAP TRIM28 CPSF1 GCN1

4.12e-05120110527320910
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP2 ACACB WDR70 LARP1 YTHDC2 AASDHPPT PFKP MDH2 TCERG1 TRIM28 GCN1 RPL13

4.14e-059341101233916271
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

ATP6V1B2 RANBP2 ACACB LARP1 PFKP NDUFA9 COTL1 ARPC2 TRIM28 DYNC1H1

5.15e-056651101030457570
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

PFKP CDC45 GCN1 DYNC1H1

5.20e-0564110422865885
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

POLR2B SPTBN1 LARP1 YTHDC2 MDH2 TCERG1 TRIM28 RBM19 UTP20 GCN1 DYNC1H1

5.20e-058071101122681889
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RANBP2 POLR2B LARP1 PFKP NDUFA9 TRRAP ARPC2 TRIM28 SLC25A1 PCBD1 GCN1 OBI1 DYNC1H1 XPO7

5.50e-0512841101417353931
Pubmed

Quantitative analysis of PPT1 interactome in human neuroblastoma cells.

SPTBN1 MDH2 TRIM28 SLC25A1 GCN1 DYNC1H1

5.73e-05210110626217791
Pubmed

Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle.

GPSM2 DYNC1H1

5.92e-054110227462074
Pubmed

Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.

UGT1A8 UGT1A9

5.92e-054110218946804
Pubmed

Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.

UGT1A8 UGT1A9

5.92e-054110220147615
Pubmed

Mapping of the 75-kDa inositol polyphosphate-5-phosphatase (Inpp5b) to distal mouse chromosome 4 and its exclusion as a candidate gene for dysgenetic lens.

GRIK3 FOXE3

5.92e-05411028530037
Pubmed

Selective interference with TRPC3/6 channels disrupts OX1 receptor signalling via NCX and reveals a distinct calcium influx pathway.

TRPC3 HCRTR1

5.92e-054110220728215
Pubmed

Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells.

GPSM2 DYNC1H1

5.92e-054110223389635
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTB SPTBN1

5.92e-054110221566095
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTB SPTBN1

5.92e-05411023862089
Pubmed

Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.

SPTB SPTBN1

5.92e-054110221412925
Pubmed

BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.

MYO9A ARFGEF1

5.92e-054110215644318
Pubmed

Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A.

PPP2R2B SULT4A1

5.92e-054110220920535
Pubmed

Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.

SPTBN1 SEMA3A

5.92e-054110234812142
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

TRPC7 TRPC3

5.92e-054110230017393
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

3.52e-0477521113
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D9 NSMAF

1.29e-03137521146
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2B PPP2R2C

1.72e-0315752696
GeneFamilyDyneins, axonemal

DNAH14 DNAH1

2.22e-0317752536
GeneFamilyV-type ATPases

ATP6V1B2 ATP6V1E2

4.06e-0323752415
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP27 MMP24

4.42e-0324752891
GeneFamilyTubulins

TUBB8 TUBB6

5.17e-0326752778
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPC3

5.99e-0328752249
CoexpressionONKEN_UVEAL_MELANOMA_UP

ACACB TRIO SPTBN1 ARFGEF1 LARP1 PFKP TRRAP COTL1 ARPC2 TCERG1 PIK3C2A CPSF1 PLTP ABTB2 SOAT1 NSMAF

1.99e-0779011016M12490
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

MRC1 ATP6V1B2 RTL6 HTR2B MMP27 CHSY1 PFKP COTL1 PGM1 TBC1D9 ARPC2 TYRO3 TUBB6 TANC1 OBI1 PLTP SOAT1

1.64e-05124211017M1920
CoexpressionBLALOCK_ALZHEIMERS_DISEASE_DN

RANBP2 MAGEL2 POLR2B PEX3 AASDHPPT MDH2 USP9Y TRRAP ENOPH1 PGM1 ARPC2 PPP2R2B BCL11B TCERG1 SULT4A1 DYNC1H1 XPO7

1.74e-05124811017M17728
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

MRC1 ATP6V1B2 RTL6 HTR2B MMP27 CHSY1 PFKP COTL1 PGM1 TBC1D9 ARPC2 TYRO3 TUBB6 TANC1 OBI1 PLTP SOAT1

3.41e-05131611017MM1052
CoexpressionABRAMSON_INTERACT_WITH_AIRE

RANBP2 POLR2B TRIM28 GCN1

3.50e-05441104M2536
CoexpressionAIZARANI_LIVER_C20_LSECS_3

MRC1 MYO10 CHSY1 TUBB6 PIEZO2 TCERG1 TANC1 PLTP

3.55e-052951108M39121
CoexpressionMEBARKI_HCC_PROGENITOR_WNT_DN

MRC1 ACACB SPTB BCO2 DHRS9

4.37e-05921105M38983
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPC7 ACACB MYO10 HS6ST1 SULT4A1 ABTB2

2.08e-061511106f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC3 WNT10B DNAH1 TYRO3 PPP2R2C MYBPC3

4.71e-06174110676310c0af1d7df6a4de3816838b2ac2892f68746
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACACB CHSY1 TBC1D9 PPP2R2B HS6ST1 ABTB2

5.54e-061791106d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 GRIK3 DNAH1 PIEZO2 DGKK MYH15

6.49e-0618411062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 GRIK3 DNAH1 PIEZO2 DGKK MYH15

6.49e-061841106ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 GRIK3 DNAH1 PIEZO2 DGKK MYH15

6.49e-0618411062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO9A GTF2IRD1 ITGB8 DNAH14 ABTB2

8.78e-06194110693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO9A GTF2IRD1 ITGB8 DNAH14 ABTB2

9.04e-0619511066477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MRC1 MYO10 ABCC9 SEMA3A PIEZO2 PLTP

9.58e-061971106f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 PPP2R2B PIEZO2 TLL2 TANC1 ABTB2

1.04e-0520011066a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 PPP2R2B PIEZO2 TLL2 TANC1 ABTB2

1.04e-0520011068d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

GRIK3 PPP2R2B PIEZO2 TLL2 TANC1 ABTB2

1.04e-052001106cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTB GRIK3 SEMA3A MRAP2 ABTB2

1.54e-051261105a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCelldroplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 TUBB6 MMP24 PLTP UNC13A

4.98e-051611105f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

CYP17A1 TRPC3 MMP24 DGKK UNC13A

4.98e-0516111055f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCelldroplet-Lung-nan-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 TUBB6 MMP24 PLTP UNC13A

4.98e-051611105110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 RTL6 DHRS9 PLTP ABTB2

5.13e-0516211052f19539c455d1e5d514725845234c7547020e6ad
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UPRT TEKT2 CPSF1 TANC1 PLTP

5.93e-051671105774f3264318b002d0df5d06d41d645366038d0bf
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DET1 MMP27 PPP2R2B BCO2 DHRS9

6.45e-051701105d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 SPTBN1 SEMA3A TUBB6 PIEZO2

7.01e-0517311057dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DET1 MMP27 PPP2R2B BCO2 DHRS9

7.60e-051761105c0a084f7a8645262d61971f094689e02bf15b113
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK3 ITGB8 DNAH14 SEMA3A TYRO3

7.60e-0517611050710689e66deba179b0a8038cdd56b4834984f12
ToppCellfacs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DET1 MMP27 PPP2R2B BCO2 DHRS9

7.60e-051761105cccf9201f6e2da7524b911a5961d3b227edab222
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 TBC1D9 GNAT1 SOAT1

7.60e-051761105b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC9 GRIK3 ITGB8 DNAH14 TYRO3

7.81e-051771105921783ed0fe20294d2f384d9136924b679df01bb
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ATP6V1B2 TBC1D9 GNAT1 SOAT1

7.81e-05177110567cc3a6461db5e0678f96b18224aeb83ad34b0f4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK3 ITGB8 DNAH14 SEMA3A TYRO3

8.02e-0517811056f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 TBC1D9 PIEZO2 PLTP RPL13

8.23e-051791105ba64bfb757d6e3be631ee95abfa24b47861f6a14
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK3 ITGB8 DNAH14 SEMA3A TYRO3

8.23e-0517911051ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCelldroplet-Lung-1m-Hematologic-myeloid|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 ATP6V1B2 COTL1 ARPC2 SOAT1

8.23e-0517911056d2458a887047b5c20389f08345ff5aac7c683e6
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GRIK3 PPP2R2B SULT4A1 UNC13A FOXD4

8.23e-051791105af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 TBC1D9 HS6ST1 ABTB2

8.45e-051801105788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK3 ITGB8 DNAH14 SEMA3A TYRO3

8.67e-0518111059de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RTL6 PPP2R2C SULT4A1 UNC13A

8.67e-0518111057af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIK3 ITGB8 DNAH14 SEMA3A TYRO3

9.37e-0518411059a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCC9 MDH2 ITGB8 SEMA3A TYRO3

9.37e-051841105219bd3b8daa0a713fb6a8a5e1bb35cdb85bb7727
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO10 TRPC3 CHSY1 ABCC9 TANC1

9.61e-051851105a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell18-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

GRIK3 PPP2R2B PPP2R2C SULT4A1 UNC13A

9.61e-051851105d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 TBC1D9 HS6ST1 ABTB2

9.86e-05186110508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell|TCGA-Uvea / Sample_Type by Project: Shred V9

HTR2B LARP1 PFKP PGM1 NSMAF

9.86e-051861105e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

MYO10 SPTB HS6ST1 DHRS9 TANC1

1.01e-041871105f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

MYO10 SPTB HS6ST1 DHRS9 TANC1

1.01e-041871105da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellfacs-MAT-Fat-18m|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHSY1 MDH2 COTL1 ARPC2 RPL13

1.04e-0418811057f0cda7aab442aa9511d4c35569ec2389e014a71
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 MYO10 PIK3C2A TLL2 TANC1

1.04e-041881105b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 TBC1D9 HS6ST1 ABTB2

1.06e-0418911058ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 TBC1D9 HS6ST1 ABTB2

1.09e-0419011054836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

FRAS1 CHSY1 GTF2IRD1 TBC1D9 HS6ST1

1.14e-041921105d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CFuPNs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

ATP6V1B2 HTR2B AASDHPPT BCL11B SULT4A1

1.14e-041921105a8841ebd879f1c344ab4246fdef77044170f644d
ToppCell11.5-Distal|11.5 / Age, Tissue, Lineage and Cell class

MYO10 SEMA3A PIEZO2 PLTP RPL13

1.14e-041921105169b9ee2377beb9e4ad35bc82bb7a3dafe8f05b6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPC7 GRIK3 PIEZO2 TLL2 TANC1

1.17e-041931105c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1|TCGA-Endometrium / Sample_Type by Project: Shred V9

ATP6V1B2 FRAS1 RTL6 ENOPH1 GPSM2

1.17e-041931105c2673d86f7d7b849788036032a93a6d136a70040
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 SPTBN1 SEMA3A TUBB6 PIEZO2

1.17e-041931105bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2IRD1 BCL11B TRIM28 HS6ST1 ABTB2

1.20e-041941105f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast|World / Lineage, cell class and subclass

CDC45 PIEZO2 DHRS9 PCBD1 PLTP

1.20e-041941105f054d78429364622d402ce1d9bf6ad13a1a1bf7e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO PFKP GTF2IRD1 TBC1D9 ABTB2

1.20e-04194110546070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 TBC1D9 PPP2R2B HS6ST1 ABTB2

1.20e-0419411054579b4a44f7c731553a284843c296866027d7c0e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO10 TRPC3 SPTBN1 PIEZO2 TANC1

1.20e-041941105b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO PFKP GTF2IRD1 TBC1D9 ABTB2

1.20e-041941105abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 ITGB8 DNAH14 ABTB2

1.20e-0419411057002937e8903e037332a215d00fbc7c7843b33f2
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2IRD1 BCL11B TRIM28 HS6ST1 ABTB2

1.20e-041941105cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 GTF2IRD1 ITGB8 DNAH14 ABTB2

1.20e-0419411055eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

FRAS1 ACACB BCO2 TANC1 MYBPC3

1.20e-041941105c3535f7cc0076653c72db582047cff053c322397
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2IRD1 BCL11B TRIM28 HS6ST1 ABTB2

1.20e-04194110566c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPC3 SPTBN1 SEMA3A PIEZO2 RPL13

1.20e-041941105a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO10 TRPC3 COTL1 SEMA3A PIEZO2

1.23e-041951105c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTF2IRD1 BCL11B TRIM28 HS6ST1 ABTB2

1.23e-04195110579114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellMacrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MRC1 ATP6V1B2 COTL1 DHRS9 SOAT1

1.23e-041951105eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 TBC1D9 PPP2R2B HS6ST1 ABTB2

1.23e-0419511053d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO9A GTF2IRD1 ITGB8 DNAH14

1.26e-0419611056ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO9A GTF2IRD1 DNAH14 ABTB2

1.26e-041961105eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellBasal-basal-6|World / Class top

COTL1 ARPC2 TUBB6 GPSM2 RPL13

1.29e-041971105b4de7ffa078d90dda243ff511ec6c503ee5d8e94
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MRC1 TBC1D9 TUBB6 PLTP SOAT1

1.29e-0419711055fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

MYO10 ABCC9 ITGB8 PCBD1 PLTP

1.32e-0419811053811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 SPTBN1 SEMA3A TUBB6 PIEZO2

1.32e-0419811055d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCellSepsis-URO-Lymphocyte-T/NK-CD8+_T_naive|URO / Disease, condition lineage and cell class

ACACB ITGB8 RHPN1 BCL11B RPL13

1.32e-041981105c07426d4119b53e58eb5f448ae364f47cac1fc5c
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 SPTBN1 SEMA3A TUBB6 PIEZO2

1.32e-04198110599d6a64f3410dae3019161feef20a8f06081a24b
ToppCellMacrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

ATP6V1B2 COTL1 TUBB6 DHRS9 PLTP

1.35e-041991105b51bcbe1675b9665e649a6aa96b1a00575a36093
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC7 GRIK3 PIEZO2 TANC1 ABTB2

1.38e-042001105a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC7 GRIK3 PIEZO2 TANC1 ABTB2

1.38e-04200110533b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Cortical_neuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

SPTBN1 GRIK3 COTL1 PPP2R2B BCL11B

1.38e-042001105458fb0f40c1720f1cacedf78c40bd059692bfc62
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MRC1 MYO10 ABCC9 PIEZO2 PLTP

1.38e-042001105ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

TRPC7 GRIK3 PIEZO2 TANC1 ABTB2

1.38e-0420011059719fabddc34051949468a7520289e3c750de4f8
ToppCellBL-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MRC1 TBC1D9 TUBB6 PLTP RPL13

1.38e-042001105dc3d5af1d4b15cc258d456f9f450550874456299
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial|3m / Sample Type, Dataset, Time_group, and Cell type.

MYO10 ITGB8 PGM1 PCBD1 PLTP

1.38e-04200110538b51f337e183011e3ff32997ec26d8a424c6b78
Drugmagnesium

ATP6V1B2 RANBP2 TUBB8 TRPC3 POLR2B SPTBN1 MMP27 AASDHPPT NT5C3B GRIK3 PFKP MDH2 DCTD ENOPH1 PGM1 DNAH1 ARPC2 TUBB6 PHKG1 MMP24 PIK3C2A DYNC1H1

2.63e-07132510922CID000000888
Diseasefacial paralysis (implicated_via_orthology)

TUBB8 TUBB6 TUBB8B

5.46e-06101073DOID:13934 (implicated_via_orthology)
Diseasecomplex cortical dysplasia with other brain malformations 7 (implicated_via_orthology)

TUBB8 TUBB6 TUBB8B

5.46e-06101073DOID:0090132 (implicated_via_orthology)
Diseaseptosis (implicated_via_orthology)

TUBB8 TUBB6 TUBB8B

5.46e-06101073DOID:0060260 (implicated_via_orthology)
Diseasetubulinopathy (implicated_via_orthology)

TUBB8 TUBB6 TUBB8B

5.46e-06101073DOID:0112227 (implicated_via_orthology)
Diseasecerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)

TUBB8 TUBB6 TUBB8B

9.96e-06121073DOID:0050997 (implicated_via_orthology)
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A8 UGT1A9

3.90e-0531072EFO_0022216
Diseaseindole-3-carboxylate measurement

UGT1A8 UGT1A9

3.90e-0531072EFO_0800043
DiseaseArthrogryposis

MAGEL2 MYO9A DYNC1H1

5.88e-05211073C0003886
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

7.78e-0541072DOID:0050882 (implicated_via_orthology)
Diseasecongenital myasthenic syndrome (is_implicated_in)

MYO9A SLC25A1

7.78e-0541072DOID:3635 (is_implicated_in)
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A8 UGT1A9

1.29e-0451072EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A8 UGT1A9

1.29e-0451072EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A8 UGT1A9

1.29e-0451072EFO_0801853
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A8 UGT1A9

1.94e-0461072EFO_0800566
DiseaseX-21339 measurement

UGT1A8 UGT1A9

2.70e-0471072EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0021260
DiseaseSuccinimide measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0022118
DiseaseX-11530 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0800696
DiseaseX-10458 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0800692
DiseaseX-24849 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0600043
Diseaseplasma clozapine measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0802740
DiseaseX-16946 measurement

UGT1A8 UGT1A9

3.60e-0481072EFO_0800766
DiseaseX-11442 measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0021236
DiseaseX-11441 measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0801036
DiseaseX-11880 measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A8 UGT1A9

4.61e-0491072EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A8 UGT1A9

4.61e-0491072EFO_0020691
Diseaseindoleacetate measurement

UGT1A8 UGT1A9

5.75e-04101072EFO_0021015
DiseaseX-21448 measurement

UGT1A8 UGT1A9

5.75e-04101072EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A8 UGT1A9

5.75e-04101072EFO_0802185
DiseaseX-23974 measurement

UGT1A8 UGT1A9

5.75e-04101072EFO_0800867
Diseasebilirubin measurement, response to tenofovir

UGT1A8 UGT1A9

5.75e-04101072EFO_0004570, EFO_0009279
DiseaseCongenital myasthenic syndrome

MYO9A SLC25A1

5.75e-04101072cv:C0751882
DiseaseX-21796 measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0800825
Diseasepregnenetriol sulfate measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0600039
Diseaseinsomnia, bilirubin measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0800972
Diseasealdosterone measurement

UGT1A8 UGT1A9

7.01e-04111072EFO_0010219
Diseasebiliverdin measurement

UGT1A8 UGT1A9

8.40e-04121072EFO_0021033
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2B PPP2R2C

8.40e-04121072DOID:1441 (implicated_via_orthology)
Diseaseairway wall thickness measurement

NT5C3B BCL11B

8.40e-04121072EFO_0006898
Diseasenicotine dependence (implicated_via_orthology)

TRPC7 TRPC3

8.40e-04121072DOID:0050742 (implicated_via_orthology)
Diseasebrain disease (is_implicated_in)

RANBP2 PPP2R2B

8.40e-04121072DOID:936 (is_implicated_in)
Diseasep-cresol glucuronide measurement

UGT1A8 UGT1A9

8.40e-04121072EFO_0800079
Diseasehealth literacy measurement

MMP27 PPP2R2C UTP20

9.52e-04531073EFO_0010104
DiseaseX-24588 measurement

UGT1A8 UGT1A9

9.90e-04131072EFO_0800898
Diseaseretinol dehydrogenase 16 measurement

UGT1A8 UGT1A9

9.90e-04131072EFO_0802007
DiseasePrader-Willi Syndrome

MAGEL2 MRAP2

9.90e-04131072C0032897
Diseasepregnenetriol disulfate measurement

UGT1A8 UGT1A9

9.90e-04131072EFO_0800587
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

CDC45 SLC25A1

1.15e-03141072DOID:0060413 (implicated_via_orthology)
DiseaseInsulin Sensitivity

MRC1 ACACB PLTP

1.37e-03601073C0920563
DiseaseInsulin Resistance

MRC1 ACACB PLTP

1.37e-03601073C0021655
DiseaseX-21441 measurement

UGT1A8 UGT1A9

1.71e-03171072EFO_0800814
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A8 UGT1A9

1.71e-03171072EFO_0004611, EFO_0007800
Diseaseattention deficit hyperactivity disorder

RANBP2 UGT1A8 UGT1A9 SEMA3A MMP24 TLL2

1.87e-033541076EFO_0003888
Diseaseangiopoietin-related protein 1 measurement

UGT1A8 UGT1A9

1.92e-03181072EFO_0801382
DiseaseCongenital Myasthenic Syndromes, Presynaptic

MYO9A SLC25A1

2.14e-03191072C0751884
Diseasetissue factor measurement

UGT1A8 UGT1A9

2.62e-03211072EFO_0010623
DiseaseS-7-hydroxywarfarin to S-warfarin ratio measurement

PPP2R2B TCERG1 NSMAF

3.22e-03811073EFO_0803334
DiseaseHbA1c measurement

ACACB SPTB LARP1 IP6K1 PFKP COTL1 PPP2R2C MYBPC3

3.23e-036751078EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
DRFAASNFGKERFVK

UNC13A

921

Q9UPW8
DFDMTLSRFAYNGKR

NT5C3B

41

Q969T7
FFRMFDRNTKRDVTL

PPP2R2B

361

Q00005
FFRMFDRNTKRDVTL

PPP2R2C

361

Q9Y2T4
KERFGDFMLFGSLAA

HTR2B

211

P41595
FVFARDAKAAMAGRL

AASDHPPT

51

Q9NRN7
TNAEAMEVRFFRGQF

BTNL8

46

Q6UX41
DFSGKDFVSALRMFL

ARFGEF1

771

Q9Y6D6
FMQEFKEGRRASHTA

ARPC2

181

O15144
SLAFFRMVDIFDGKI

ABCC9

1356

O60706
RDAFQMATRLSKFFS

DNHD1

1846

Q96M86
RAEQDGSAMAKRRFF

DET1

306

Q7L5Y6
GSAMAKRRFFQYFDQ

DET1

311

Q7L5Y6
NVFERFMSRFELPGK

BCO2

156

Q9BYV7
RAAMRRSFSADNFIG

CCNYL1

336

Q8N7R7
EALMFDRSFVGKQFS

PGM1

446

P36871
KNSGFRRSDDMFTFH

RANBP2

1121

P49792
NGMKEERFRQLFAAF

RBM19

11

Q9Y4C8
MGAMVAFRRFEDFTR

ACACB

1366

O00763
FAELFSFMLQDRAKG

FEM1C

386

Q96JP0
TVALFRGEMFVFKDR

MMP24

386

Q9Y5R2
DAITTFRREVMFFKG

MMP27

286

Q9H306
AGLSMFKNFARFRIL

DGKK

531

Q5KSL6
ERDFFLRRKMDADGF

LARP1

421

Q6PKG0
DFKSRGMSAASRVIF

FRAS1

2726

Q86XX4
GFFDLLSRFQSNRMD

GPSM2

491

P81274
FRAIFMADAFSELQA

MAD2L1BP

191

Q15013
FMKGNCVREDLIFNF

MAGEL2

1121

Q9UJ55
SFKDLNFRMFDVGGQ

GNAT1

186

P11488
ARFVFSLVDAMNGKE

MDH2

256

P40926
TDGMRSVRAFHFDKA

CPSF1

351

Q10570
KDFNRAFGFMTRVAL

PCBD1

41

P61457
DMDFRGAFFPLTERN

PLTP

231

P55058
AQMFGSFKRDRAPFV

PIK3C2A

1276

O00443
FDRNFGTKISARAME

PFKP

681

Q01813
RGFSRLLDNMAEFFR

PEX3

286

P56589
RLFEDQRFGSSLFKM

OBI1

661

Q5W0B1
RGLAMEDSRNMFALF

MYO10

1731

Q9HD67
NFRRREGALFAFEML

GCN1

1431

Q92616
FMAFNRGKREGFFLK

RPS6KA4

706

O75676
DMFDNGSFLRRRKRF

FOXD4

186

Q12950
IFGREDRFLNSFASM

NDUFA9

206

Q16795
AFRKFRTNFDFMILN

GPR75

71

O95800
RGMAFFGLTEFQRKT

HS6ST1

286

O60243
TESFVFKANGFMALR

OR56B2P

146

Q8NGI1
NDLSRKMAFFSRDFR

ITGB8

171

P26012
KRVFGMFRQASDREA

HCRTR1

321

O43613
RDFLRSMENAIRFGK

DNAH1

3261

Q9P2D7
AFTAGRMKAEFFADV

ENOPH1

121

Q9UHY7
SDRKNFFGRAFEKAA

CDC45

516

O75419
FMKDPFLGFTDARQS

BCL11B

721

Q9C0K0
VRLFAFVRFTTGDAM

COTL1

56

Q14019
ARLLFNMAGVTFRKF

DCTD

141

P32321
RLAMATFALFKDGDQ

CYP17A1

126

P05093
CRILDAFFDFMGKNG

DNAH14

1701

Q0VDD8
RMIDFAHSTFKGFRD

IP6K1

396

Q92551
KNANEMFRIFSRFNA

DYNC1H1

576

Q14204
GRFDNADRMFNSIAE

NSMAF

416

Q92636
FVMFRKSDRTLYGND

GRIK3

446

Q13003
FIIKRMFDERIFTGN

GTF2IRD1

421

Q9UHL9
RFVLAVGSAVFDAMF

BTBD2

136

Q9BX70
FNDSLRRDMKAFGVH

DHRS9

186

Q9BPW9
FKAFASLRMARANAR

RPL13

176

P26373
TNTFFFLVFDLMKRG

PHKG1

96

Q16816
MDNARAFCKRNFGDL

MRC1

821

P22897
LFGAFFEATMIDRKI

FER1L6

481

Q2WGJ9
RFMIFQASRFPGEAE

RTL6

121

Q6ICC9
ARFFKSDFEENGSMD

ATP6V1B2

241

P21281
RNFAAESFTFLMRKV

UTP20

186

O75691
FFGMAFNFIVNDSRK

SOAT1

481

P35610
NDNSSRFGKFIRMHF

MYH15

251

Q9Y2K3
AADMFDNGSFLRRRK

FOXE3

151

Q13461
MNRSAVDRGFFRSVF

POLR2B

796

P30876
FEMVNFKEEGFGLRA

SETD3

96

Q86TU7
RRKTNDFGMAEEFAS

TANC1

1346

Q9C0D5
FSRFNKDRAEAEMKA

TEKT2

221

Q9UIF3
AADFMGRDFAIFRTL

SEMA3A

191

Q14563
RAMEAFQRAAGAFSL

RHPN1

241

Q8TCX5
RLVDTGDKFRFFSMV

SPTBN1

1906

Q01082
AATEKFNQDLGFRML

ABTB2

481

Q8N961
SGRFDMFVRFMGNFE

CHSY1

541

Q86X52
SEKRFRMNSFVSDFG

MRAP2

81

Q96G30
GTFQEFCRRFMNDKL

SULT4A1

156

Q9BR01
ELFKRISEQFSAMFR

TUBB6

376

Q9BUF5
ISEQFSAMFRRKAFL

TUBB6

381

Q9BUF5
ELFKRVSEQFTAMFR

TUBB8

376

Q3ZCM7
VSEQFTAMFRRKAFL

TUBB8

381

Q3ZCM7
MKDREALFNEFVAAA

TCERG1

766

O14776
FAGMDASFKAFRSLQ

WDR70

211

Q9NW82
EFGAKRKFTQSFMRS

STYXL2

1081

Q5VZP5
FFTRAFDQLRMGAIS

TKTL2

396

Q9H0I9
NRMTFLFANLKDRDF

TBC1D9

376

Q6ZT07
VSEQFTAMFRRKAFL

TUBB8B

381

A6NNZ2
KFIQAFSRDTGAMQF

PIEZO2

2471

Q9H5I5
MFLRFYSDASVQRKG

TLL2

866

Q9Y6L7
PKAAVRFGMFEFLSN

SLC25A1

96

P53007
DTADKFRFFSMARDL

SPTB

1901

P11277
SLLTENGMKCFERFF

USP9Y

731

O00507
GFSDAMTFKERVRNH

UGT1A9

196

O60656
RKRFTAGAFSDHMAL

YTHDC2

886

Q9H6S0
LRGIAFAFNAKTSFM

XPO7

726

Q9UIA9
KRGFRESAFSFSMLA

WNT10B

111

O00744
TESFQFLDRMRAAGK

GTF3C1

1521

Q12789
IRDKTASRGDFMFSA

UPRT

126

Q96BW1
AKFFEVFDNSMKRRV

TRRAP

2456

Q9Y4A5
KETRFGQAFDSVMAR

TYRO3

456

Q06418
IAAFFRSGFRKNDEM

TRIO

46

O75962
DFGMLSIFIAAFTAR

TRPC3

461

Q13507
IGLQRFFETRMNEAF

TRIM28

786

Q13263
FTARFMAFLKATEAQ

TRPC7

486

Q9HCX4
GFSDAMTFKERVRNH

UGT1A8

196

Q9HAW9
IRMALFGANTNRKFF

ATP6V1E2

211

Q96A05
RAFFRAMVAFREAGK

MYO9A

706

B2RTY4
LGEDARFRMFSKQGV

MYBPC3

1221

Q14896