Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH12 DNAH17 DNAAF6 DNAH7

2.59e-0737755GO:0045505
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH12 DNAH17 DNAH7

5.40e-0718754GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH12 DNAH17 DNAH7

3.51e-0628754GO:0051959
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH12 DNAH17 DNAH7

1.40e-0470754GO:0003777
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine kinase activity

MAPKAPK2 MAPKAPK3

6.14e-0410752GO:0009931
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 DNAH12 DNAH17 DNAH7

1.02e-03118754GO:0003774
GeneOntologyMolecularFunctionRNA polymerase III general transcription initiation factor activity

GTF3C1 SNAPC1

1.06e-0313752GO:0000995
GeneOntologyMolecularFunctionATP hydrolysis activity

CCT6A DNAH3 DNAH12 ATRX DHX40 ABCC2 DNAH7

1.33e-03441757GO:0016887
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

LIMK1 GRK2 NUAK1 MTOR MAPKAPK2 MAPKAPK3 PLK1

1.42e-03446757GO:0004674
GeneOntologyBiologicalProcesscilium movement involved in cell motility

FSIP2 DNAH3 DNAH12 DNAH17 DNAAF6 CFAP44 DNAH7 CCDC39

7.70e-07210738GO:0060294
GeneOntologyBiologicalProcessmicrotubule bundle formation

FSIP2 DNAH17 DNAAF6 PLK1 CFAP44 DNAH7 CCDC39

8.11e-07145737GO:0001578
GeneOntologyBiologicalProcesscilium-dependent cell motility

FSIP2 DNAH3 DNAH12 DNAH17 DNAAF6 CFAP44 DNAH7 CCDC39

9.20e-07215738GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

FSIP2 DNAH3 DNAH12 DNAH17 DNAAF6 CFAP44 DNAH7 CCDC39

9.20e-07215738GO:0001539
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

CCDC170 FSIP2 DST ATRX DNAH17 SYNE2 DNAAF6 CKAP2 PLK1 CFAP44 CAMSAP2 DNAH7 CCDC39

1.28e-067207313GO:0000226
GeneOntologyBiologicalProcessaxoneme assembly

FSIP2 DNAH17 DNAAF6 CFAP44 DNAH7 CCDC39

2.42e-06109736GO:0035082
GeneOntologyBiologicalProcessmicrotubule-based process

CCDC170 FSIP2 DNAH3 DNAH12 DST ATRX DNAH17 SYNE2 DNAAF6 CKAP2 PLK1 CFAP44 CAMSAP2 DNAH7 CCDC39

3.58e-0610587315GO:0007017
GeneOntologyBiologicalProcesscilium movement

FSIP2 DNAH3 DNAH12 DNAH17 DNAAF6 CFAP44 DNAH7 CCDC39

3.90e-06261738GO:0003341
GeneOntologyBiologicalProcessmicrotubule-based movement

FSIP2 DNAH3 DNAH12 DST DNAH17 SYNE2 DNAAF6 CFAP44 DNAH7 CCDC39

8.96e-064937310GO:0007018
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAH17 DNAAF6 DNAH7 CCDC39

1.32e-0541734GO:0070286
GeneOntologyBiologicalProcessinner dynein arm assembly

DNAAF6 DNAH7 CCDC39

2.79e-0517733GO:0036159
GeneOntologyBiologicalProcesspositive regulation of collagen fibril organization

RB1 TNXB

7.38e-054732GO:1904028
GeneOntologyBiologicalProcessneuron projection development

SHANK1 LIMK1 DST RAPH1 RB1 MTOR SH3GL2 LAMA1 DOCK10 GRID2 POTEJ CAMSAP2 TNXB CYFIP2

1.43e-0412857314GO:0031175
GeneOntologyBiologicalProcesscell projection assembly

STX2 FSIP2 MTOR DNAH17 SYNE2 DNAAF6 CFAP44 DNAH7 CCDC39 CYFIP2

1.44e-046857310GO:0030031
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

SHANK1 LIMK1 RB1 MTOR CKAP2 CAMSAP2 TNXB CYFIP2

1.56e-04438738GO:1902903
GeneOntologyBiologicalProcessneuron development

SHANK1 LIMK1 DST RAPH1 RB1 MTOR CABP4 SH3GL2 LAMA1 DOCK10 GRID2 POTEJ CAMSAP2 TNXB CYFIP2

1.56e-0414637315GO:0048666
GeneOntologyBiologicalProcess'de novo' pyrimidine nucleobase biosynthetic process

CMPK1 MTOR

1.84e-046732GO:0006207
GeneOntologyBiologicalProcessregulation of organelle organization

SHANK1 CUL3 CCT6A LIMK1 ATRX RB1 MTOR SYNE2 GRID2 CKAP2 PLK1 CAMSAP2 CLEC16A CYFIP2

2.25e-0413427314GO:0033043
GeneOntologyBiologicalProcesscell morphogenesis

SHANK1 CUL3 LIMK1 DST RAPH1 RB1 CABP4 SH3GL2 LAMA1 DOCK10 POTEJ CFAP44 CYFIP2

2.57e-0411947313GO:0000902
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SHANK1 LIMK1 DST RAPH1 RB1 CABP4 LAMA1 DOCK10 POTEJ CYFIP2

2.92e-047487310GO:0048667
GeneOntologyBiologicalProcesspyrimidine nucleobase biosynthetic process

CMPK1 MTOR

3.41e-048732GO:0019856
GeneOntologyBiologicalProcessregulation of collagen fibril organization

RB1 TNXB

4.38e-049732GO:1904026
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH12 DNAH17 DNAH7

1.93e-0625764GO:0005858
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH12 DNAH7

5.44e-0610763GO:0036156
GeneOntologyCellularComponentmicrotubule

CUL3 CCT6A DNAH3 DNAH12 DST DNAH17 CKAP2 PLK1 CAMSAP2 DNAH7

2.25e-055337610GO:0005874
GeneOntologyCellularComponent9+2 motile cilium

CUL3 FSIP2 DNAH3 DNAH12 DNAH17 DNAH7 CCDC39

2.55e-05238767GO:0097729
GeneOntologyCellularComponentmotile cilium

CUL3 FSIP2 DNAH3 DNAH12 DNAH17 CFAP44 DNAH7 CCDC39

4.41e-05355768GO:0031514
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH12 DNAH17 DNAH7

4.44e-0554764GO:0030286
GeneOntologyCellularComponentcilium

CCDC170 CUL3 FSIP2 DNAH3 EYS DNAH12 GRK2 DNAH17 CFAP44 CAMSAP2 DNAH7 CCDC39

9.03e-058987612GO:0005929
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

ZC3H14 DNAH3 DNAH12 DST DNAH17 DNAH7 CCDC39

1.54e-04317767GO:0032838
GeneOntologyCellularComponentsupramolecular fiber

CUL3 CCT6A DNAH3 DNAH12 DST ANK2 DNAH17 SYNE2 CKAP2 POTEJ PLK1 CAMSAP2 DNAH7

3.02e-0411797613GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CUL3 CCT6A DNAH3 DNAH12 DST ANK2 DNAH17 SYNE2 CKAP2 POTEJ PLK1 CAMSAP2 DNAH7

3.22e-0411877613GO:0099081
GeneOntologyCellularComponentcytoplasmic region

ZC3H14 DNAH3 DNAH12 DST DNAH17 DNAH7 CCDC39

3.34e-04360767GO:0099568
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

CUL3 CCT6A DNAH3 DNAH12 DST DNAH17 CKAP2 POTEJ PLK1 CAMSAP2 DNAH7

3.89e-048997611GO:0099513
GeneOntologyCellularComponentaxoneme

DNAH3 DNAH12 DNAH17 DNAH7 CCDC39

9.48e-04207765GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 DNAH12 DNAH17 DNAH7 CCDC39

9.68e-04208765GO:0097014
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA1 TNXB

1.71e-0317762GO:0098637
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH12 DNAH7

1.71e-0514693IPR024317
DomainDynein_heavy_dom-2

DNAH3 DNAH12 DNAH7

1.71e-0514693IPR013602
DomainDHC_N2

DNAH3 DNAH12 DNAH7

1.71e-0514693PF08393
DomainAAA_8

DNAH3 DNAH12 DNAH7

1.71e-0514693PF12780
DomainDHC_fam

DNAH3 DNAH12 DNAH7

2.13e-0515693IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH12 DNAH7

2.13e-0515693IPR004273
DomainDynein_heavy

DNAH3 DNAH12 DNAH7

2.13e-0515693PF03028
DomainMAPKAPK_C

MAPKAPK2 MAPKAPK3

4.03e-053692IPR027442
Domain-

MAPKAPK2 MAPKAPK3

4.03e-0536924.10.1170.10
DomainCa/CaM-dep_Ca-dep_prot_Kinase

NUAK1 MAPKAPK2 MAPKAPK3 PLK1

1.23e-0469694IPR020636
DomainKinase-like_dom

LIMK1 DST GRK2 RAPH1 NUAK1 MTOR MAPKAPK2 MAPKAPK3 PLK1

1.64e-04542699IPR011009
DomainDUF3398

DOCK9 DOCK10

2.00e-046692PF11878
DomainDOCK_C/D_N

DOCK9 DOCK10

2.00e-046692IPR021816
DomainGlyco_transf_8

GYG1 GXYLT1

5.94e-0410692PF01501
DomainGlyco_trans_8

GYG1 GXYLT1

5.94e-0410692IPR002495
DomainDOCK_C

DOCK9 DOCK10

7.24e-0411692IPR010703
DomainLaminin_G_1

EYS LAMA1

7.24e-0411692PF00054
DomainDHR-1_domain

DOCK9 DOCK10

7.24e-0411692IPR027007
DomainDHR_2

DOCK9 DOCK10

7.24e-0411692PS51651
DomainDHR_1

DOCK9 DOCK10

7.24e-0411692PS51650
DomainDOCK-C2

DOCK9 DOCK10

7.24e-0411692PF14429
DomainDHR-2

DOCK9 DOCK10

7.24e-0411692IPR027357
DomainDHR-2

DOCK9 DOCK10

7.24e-0411692PF06920
DomainDOCK

DOCK9 DOCK10

7.24e-0411692IPR026791
DomainDynein_HC_stalk

DNAH3 DNAH7

1.19e-0314692IPR024743
DomainMT

DNAH3 DNAH7

1.19e-0314692PF12777
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH12

1.19e-0314692IPR011704
DomainAAA_5

DNAH3 DNAH12

1.19e-0314692PF07728
DomainAAA+_ATPase

DNAH3 DNAH12 ABCC2 DNAH7

1.99e-03144694IPR003593
DomainAAA

DNAH3 DNAH12 ABCC2 DNAH7

1.99e-03144694SM00382
DomainSer/Thr_kinase_AS

LIMK1 GRK2 NUAK1 MAPKAPK2 MAPKAPK3 PLK1

2.04e-03357696IPR008271
DomainPROTEIN_KINASE_ST

LIMK1 GRK2 NUAK1 MAPKAPK2 MAPKAPK3 PLK1

2.18e-03362696PS00108
Domain-

DST SYNE2 CAMSAP2

2.30e-03716931.10.418.10
DomainCH

DST SYNE2 CAMSAP2

2.49e-0373693PS50021
DomainCH-domain

DST SYNE2 CAMSAP2

2.69e-0375693IPR001715
DomainProtein_kinase_ATP_BS

LIMK1 GRK2 NUAK1 MAPKAPK2 MAPKAPK3 PLK1

2.74e-03379696IPR017441
DomainPkinase

LIMK1 GRK2 NUAK1 MAPKAPK2 MAPKAPK3 PLK1

2.82e-03381696PF00069
DomainActinin_actin-bd_CS

DST SYNE2

3.24e-0323692IPR001589
DomainSpectrin

DST SYNE2

3.24e-0323692PF00435
DomainACTININ_2

DST SYNE2

3.24e-0323692PS00020
DomainACTININ_1

DST SYNE2

3.24e-0323692PS00019
DomainSpectrin_repeat

DST SYNE2

5.12e-0329692IPR002017
DomainEGF_LAM_2

ATRNL1 LAMA1

5.47e-0330692PS50027
DomainEGF_LAM_1

ATRNL1 LAMA1

5.47e-0330692PS01248
Domain-

DNAH3 CMPK1 GTPBP2 DNAH12 ATRX DHX40 ABCC2 DNAH7

6.08e-037466983.40.50.300
DomainSpectrin/alpha-actinin

DST SYNE2

6.21e-0332692IPR018159
DomainSPEC

DST SYNE2

6.21e-0332692SM00150
DomainPROTEIN_KINASE_ATP

LIMK1 GRK2 NUAK1 MAPKAPK2 MAPKAPK3 PLK1

6.93e-03459696PS00107
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH12 DNAH17 DNAH7

3.93e-0627574M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH12 DNAH17 DNAH7

2.64e-0543574M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH12 DNAH17 DNAH7

3.16e-0545574M47670
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CUL3 PIK3AP1 CCT6A GRK2 RAPH1 DHX40 SH3GL2 CKAP2 PLK1 FHIP2A CAMSAP2 CLEC16A DNAH7 ARCN1

4.31e-09853761428718761
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH12 DNAH17 DNAH7

2.07e-08147649373155
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

GTPBP2 DST GTF3C1 RB1 SYNE2

2.53e-069876534943047
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FSIP2 LIMK1 DST RAPH1 MTOR SYNE2 GAN CKAP2 PLK1 CAMSAP2 DNAH7

2.66e-06861761136931259
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

CCT6A DST SYNE2 GAN CFAP44 NUP160

3.57e-0618776626460568
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CCDC170 DNAH3 DST GTF3C1 RB1 LAMA1 CFAP44 FAM186B CCDC39 ARCN1

4.60e-06736761029676528
Pubmed

Pharmacological and genetic inhibition of downstream targets of p38 MAPK in experimental nephrotic syndrome.

MAPKAPK2 MAPKAPK3

4.71e-06276229187369
Pubmed

Hierarchical requirement of SWI/SNF in retinoblastoma tumor suppressor-mediated repression of Plk1.

RB1 PLK1

4.71e-06276215105433
Pubmed

Endophilin marks and controls a clathrin-independent endocytic pathway.

RAPH1 SH3GL2

4.71e-06276225517094
Pubmed

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.

MTOR MAPKAPK2

4.71e-06276226280535
Pubmed

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.

MTOR CYFIP2

4.71e-06276222268788
Pubmed

BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation.

PIK3AP1 MTOR

4.71e-06276230093533
Pubmed

Inhibiting PLK1 induces autophagy of acute myeloid leukemia cells via mammalian target of rapamycin pathway dephosphorylation.

MTOR PLK1

4.71e-06276228184925
Pubmed

Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis.

MAPKAPK2 MAPKAPK3

4.71e-06276223372691
Pubmed

Effects of an ectodermal microceptor preparation on motor coordination in cerebellar mutant mice.

DST GRID2

4.71e-0627627886086
Pubmed

MAPKAP kinase 3 suppresses Ifng gene expression and attenuates NK cell cytotoxicity and Th1 CD4 T-cell development upon influenza A virus infection.

MAPKAPK2 MAPKAPK3

4.71e-06276224935968
Pubmed

MK2/3 Are Pivotal for IL-33-Induced and Mast Cell-Dependent Leukocyte Recruitment and the Resulting Skin Inflammation.

MAPKAPK2 MAPKAPK3

4.71e-06276227694493
Pubmed

Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2.

MAPKAPK2 MAPKAPK3

4.71e-06276231167133
Pubmed

Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity.

MAPKAPK2 MAPKAPK3

4.71e-06276224082115
Pubmed

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.

CUL3 GAN

4.71e-06276227000625
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL3 TMED1 DNAJC13 ATRX RB1 MTOR GAN SNAPC1 PLK1 MFSD4B CAMSAP2 NUP160 EIF3CL

5.32e-061321761327173435
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 CUL3 DNAJC13 DST ANK2 MTOR SH3GL2 SYNE2 HECTD4 CAMSAP2 CYFIP2

7.68e-06963761128671696
Pubmed

Defining the membrane proteome of NK cells.

CUL3 DNAJC13 GRK2 GTF3C1 MTOR GYG1 DOCK9 DOCK10 PIGG BAG6 ARCN1 CYFIP2

8.32e-061168761219946888
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

CUL3 GTPBP2 DST GTF3C1 ATRX DHX40 DOCK10 FHIP2A CLEC16A

1.23e-0565076938777146
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

ZC3H14 LIMK1 ATRX RB1 MTOR SYNE2 CYFIP2

1.37e-0535876732460013
Pubmed

Expression profiling of G2/M phase regulatory proteins in normal, premalignant and malignant uterine cervix and their correlation with survival of patients.

LIMK1 PLK1

1.41e-05376220622363
Pubmed

Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding.

ATRX RB1

1.41e-05376236073547
Pubmed

Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3.

MAPKAPK2 MAPKAPK3

1.41e-05376221586572
Pubmed

The MK2/3 cascade regulates AMPAR trafficking and cognitive flexibility.

MAPKAPK2 MAPKAPK3

1.41e-05376225134715
Pubmed

p53 suppresses carcinoma progression by inhibiting mTOR pathway activation.

RB1 MTOR

1.41e-05376224469052
Pubmed

Stress and IGF-I differentially control cell fate through mammalian target of rapamycin (mTOR) and retinoblastoma protein (pRB).

RB1 MTOR

1.41e-05376218697743
Pubmed

Distribution of dopamine transporters in basal ganglia of cerebellar ataxic mice by [125I]RTI-121 quantitative autoradiography.

DST GRID2

1.41e-0537629460703
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK9 DOCK10

1.41e-05376232241915
Pubmed

UBAP2L-dependent coupling of PLK1 localization and stability during mitosis.

CUL3 PLK1

1.41e-05376237039032
Pubmed

Ileal neuroendocrine tumors show elevated activation of mammalian target of rapamycin complex.

ATRX MTOR

1.41e-05376225439321
Pubmed

A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress.

MAPKAPK2 MAPKAPK3

1.41e-0537628774846
Pubmed

p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins.

MAPKAPK2 MAPKAPK3

1.41e-05376220724476
Pubmed

Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27.

MAPKAPK2 MAPKAPK3

1.41e-0537627799959
Pubmed

Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2.

MAPKAPK2 MAPKAPK3

1.41e-0537628846784
Pubmed

Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity.

MAPKAPK2 MAPKAPK3

1.41e-05376210781029
Pubmed

Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.

RB1 MTOR

1.41e-05376220628002
Pubmed

Mitogen-activated protein kinase-activated protein kinases 2 and 3 regulate SERCA2a expression and fiber type composition to modulate skeletal muscle and cardiomyocyte function.

MAPKAPK2 MAPKAPK3

1.41e-05376223608535
Pubmed

Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.

MAPKAPK2 MAPKAPK3

1.41e-05376226068544
Pubmed

The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner.

MTOR PLK1

1.41e-05376229722913
Pubmed

MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration.

LIMK1 MAPKAPK2

2.82e-05476216456544
Pubmed

IL-33-activated murine mast cells control the dichotomy between RORγt+ and Helios+ Tregs via the MK2/3-mediated IL-6 production in vitro.

MAPKAPK2 MAPKAPK3

2.82e-05476231334837
Pubmed

IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction.

MAPKAPK2 MAPKAPK3

2.82e-05476233427298
Pubmed

CMPK1 and RBP3 are associated with corneal curvature in Asian populations.

CMPK1 MTOR

2.82e-05476224963161
Pubmed

Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment.

CUL3 GAN

2.82e-05476231944090
Pubmed

Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation.

MAPKAPK2 MAPKAPK3

2.82e-05476221575178
Pubmed

Vascular endothelial cell growth factor activates CRE-binding protein by signaling through the KDR receptor tyrosine kinase.

MAPKAPK2 MAPKAPK3

2.82e-05476211335727
Pubmed

CUL3 and protein kinases: insights from PLK1/KLHL22 interaction.

CUL3 PLK1

2.82e-05476224067371
Pubmed

The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.

RB1 SNAPC1

2.82e-05476211094070
Pubmed

ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.

RB1 LAMA1

2.82e-05476221115804
Pubmed

Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.

MAPKAPK2 MAPKAPK3

2.82e-05476228011639
Pubmed

Activation of mTOR modulates SREBP-2 to induce foam cell formation through increased retinoblastoma protein phosphorylation.

RB1 MTOR

2.82e-05476224068000
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

ZC3H14 DNAH3 TBRG4 DST GTF3C1 DOCK10 ARCN1

3.27e-0541076726949251
Pubmed

Role of p38alpha Map kinase in Type I interferon signaling.

MAPKAPK2 MAPKAPK3

4.69e-05576214578350
Pubmed

Human CLEC16A regulates autophagy through modulating mTOR activity.

MTOR CLEC16A

4.69e-05576228223137
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 CCDC39

4.69e-05576239056782
Pubmed

MAP kinase-activated protein kinases 2 and 3 are required for influenza A virus propagation and act via inhibition of PKR.

MAPKAPK2 MAPKAPK3

4.69e-05576220484669
Pubmed

BAG6 supports stress fiber formation by preventing the ubiquitin-mediated degradation of RhoA.

CUL3 BAG6

4.69e-05576236884293
Pubmed

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.

GTF3C1 MTOR

4.69e-05576220543138
Pubmed

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection.

MAPKAPK2 MAPKAPK3

4.69e-05576228920954
Pubmed

Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein.

RB1 PLK1

4.69e-05576228387346
Pubmed

Translational homeostasis via the mRNA cap-binding protein, eIF4E.

CUL3 MTOR

4.69e-05576222578813
Pubmed

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways.

MAPKAPK2 MAPKAPK3

4.69e-05576217906627
Pubmed

Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.

RB1 MTOR

4.69e-05576219703998
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK9 DOCK10

4.69e-05576215710388
Pubmed

The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3.

MAPKAPK2 MAPKAPK3

4.69e-05576231527197
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CCT6A CMPK1 GTPBP2 DNAJC13 DST CLEC16A DNAH7 NUP160 ARCN1

4.96e-0577776935844135
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

DNAJC13 DST ATRX SYNE2

5.08e-059276415840729
Pubmed

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.

RAPH1 SH3GL2

7.03e-05676224076656
Pubmed

Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry.

DNAH12 EIF3CL

7.03e-05676217287340
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK9 DOCK10

7.03e-05676225851601
Pubmed

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation.

MAPKAPK2 MAPKAPK3

7.03e-05676225693418
Pubmed

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

MAPKAPK2 MAPKAPK3

7.03e-05676217030606
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CUL3 DNAJC13 HECTD4 DOCK10

7.61e-051027649734811
Pubmed

p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin.

MTOR MAPKAPK2

9.83e-05776223315073
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH12

9.83e-0577629256245
Pubmed

Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression.

MAPKAPK2 PLK1

9.83e-05776218695677
Pubmed

The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells.

MAPKAPK2 MAPKAPK3

9.83e-05776232424229
Pubmed

Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.

SHANK1 GRID2

9.83e-05776215207857
Pubmed

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.

MAPKAPK2 MAPKAPK3

1.31e-04876219369945
Pubmed

Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.

CUL3 GAN

1.31e-04876215983046
Pubmed

Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3KLHL12 Ubiquitin Ligase Complex.

CUL3 MTOR

1.31e-04876232433973
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DST DOCK9 SYNE2 DOCK10 CLEC16A

1.38e-0422576512168954
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

DHX40 DNAH17 SYNE2 GAN BAG6 ARCN1

1.47e-0436376625036637
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

FSIP2 CCT6A DST SYNE2

1.57e-0412376426912792
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

LIMK1 DST GTF3C1 ATRX NUAK1 MAPKAPK2 PLK1 CYFIP2 EIF3CL

1.64e-0491076936736316
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CCT6A DNAJC13 DST GTF3C1 RB1 DHX40 DOCK10 PLK1 BAG6 NUP160 ARCN1

1.67e-041353761129467282
Pubmed

Ubiquitylation-dependent localization of PLK1 in mitosis.

CUL3 PLK1

1.68e-04976223455478
Pubmed

Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.

DST GRID2

1.68e-04976216499884
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

CUL3 BAG6 ARCN1

1.83e-045076327716508
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SHANK1 CCT6A GRK2 ANK2 DOCK9 SH3GL2 CAMSAP2 CLEC16A ARCN1 EIF3CL

1.83e-041139761036417873
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZC3H14 SDE2 DST ANK2 ATRX RAPH1 CKAP2 CAMSAP2 ARCN1

1.99e-0493476933916271
Pubmed

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.

MTOR EIF3CL

2.10e-041076216286006
Pubmed

Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.

DST GRID2

2.10e-04107621565842
Pubmed

Syntaxin 3 and Munc-18-2 in epithelial cells during kidney development.

STX2 LAMA1

2.10e-041076210469351
Pubmed

Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases.

MAPKAPK2 MAPKAPK3

2.10e-041076229229781
InteractionMYCBP2 interactions

CUL3 DST ANK2 MTOR SYNE2 CKAP2 PLK1 CLEC16A CYFIP2

6.66e-06355759int:MYCBP2
Cytoband2q36.2

CUL3 DOCK10

8.10e-0637622q36.2
CytobandEnsembl 112 genes in cytogenetic band chr16p12

DNAH3 GTF3C1 PLK1 EIF3CL

1.98e-04172764chr16p12
GeneFamilyDyneins, axonemal

DNAH3 DNAH12 DNAH17 DNAH7

9.30e-0817474536
GeneFamilyGlycosyltransferase family 8

GYG1 GXYLT1

2.35e-049472436
GeneFamilyMitogen-activated protein kinase-activated protein kinases

MAPKAPK2 MAPKAPK3

3.58e-04114721156
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GRK2 RAPH1 DOCK9 DOCK10

1.99e-03206474682
CoexpressionMURARO_PANCREAS_BETA_CELL

DST GTF3C1 ATRX RAPH1 GYG1 ATRNL1 SH3GL2 SYNE2 HECTD4 DOCK10 RUNX1T1 CYFIP2

1.69e-059467612M39169
CoexpressionGSE19374_UNINF_VS_LISTERIA_INFECTED_MACROPHAGE_DN

SHANK1 CMPK1 GTPBP2 RB1 DNAH17 TAF13

2.43e-05198766M7265
CoexpressionGSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN

PIK3AP1 GYG1 CABP4 HECTD4 NIPAL1 CAMSAP2

2.57e-05200766M9344
CoexpressionGSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP

TMED1 GTPBP2 GRK2 GTF3C1 GYG1 RUNX1T1

2.57e-05200766M9667
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZC3H14 DNAJC13 DST ATRX NUAK1 RB1 DOCK9 SYNE2 CAMSAP2 CLEC16A NUP160

3.49e-058567611M4500
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAH17 DNAAF6 DNAH7 CCDC39

1.85e-0817276708ad76412c9cc3504141797b44b88478ced87476
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

3.17e-0818676776033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

3.94e-08192767be592e661367affced9ebe80849b466e6adb3a34
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

3.94e-081927671b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.08e-081937670b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.23e-081947675aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.23e-08194767b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.38e-081957670e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.38e-08195767581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.38e-0819576793b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.38e-0819576734e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.53e-0819676727b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.70e-081977676865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.70e-08197767d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCellmedial-Epithelial-Ciliated-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-08199767526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCellmedial-Epithelial-Ciliated|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-08199767a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCellmedial-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-08199767c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-081997679700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-081997671188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.03e-081997672e8ace105c4e2405baa06d953e52888b54e2d055
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.21e-082007679ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.21e-0820076731d75c26055177d656df1fbb10b764cebd61e122
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.21e-08200767e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH3 DNAAF6 CFAP44 DNAH7 CCDC39

2.62e-071547669ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CCDC170 DNAH3 DNAAF6 CFAP44 DNAH7 CCDC39

2.62e-0715476658072ce422d09f2de602580325eaac6c4ec6c136
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

4.21e-0716776626cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

5.01e-07172766187ae91148d293537afc77e10da2b64302322224
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

6.97e-07182766975f6275777fc578eba528e50f69891c66ec44ad
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

6.97e-07182766f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

7.43e-0718476607c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

7.67e-071857665e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

7.92e-07186766f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

8.17e-071877661a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

8.43e-071887666833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

8.69e-07189766dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 ANK2 DNAAF6 DNAH7

8.69e-07189766cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellMulticiliated|World / shred by cell class for nasal brushing

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

8.69e-0718976634b110aef839376228c5a403a6b5047a945f472b
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

8.96e-071907669ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

8.96e-07190766833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

8.96e-07190766a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7

9.24e-07191766e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellmulticiliated|World / shred by cell class for turbinate

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

9.53e-071927660f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

9.82e-07193766c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

9.82e-071937660e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

9.82e-07193766aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

9.82e-07193766a0baa8be6f590b2031fede22be588715ae458e93
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7

1.01e-06194766756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.01e-061947663cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.01e-06194766c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.01e-06194766b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.01e-061947667a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.01e-061947664a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.01e-06194766a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-06195766649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-06195766d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.04e-06195766cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-06195766db4270c135c392ed443670981656e3cd5b95939d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-06195766129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-061957663e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.04e-06195766e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.04e-061957666365e3893e38231090ec2dbef010dec71dea3d07
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.04e-0619576607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.07e-06196766d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-0619776691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-0619776671fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-0619776622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH12 SYNE2 CFAP44 DNAH7 CCDC39

1.11e-0619776674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-061977663bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-06197766e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-0619776687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7 CCDC39

1.11e-06197766d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellproximal-Epithelial-Proximal_Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.14e-0619876669acfdd525c05483f496e54f36762fcbc5521bd4
ToppCellproximal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.14e-06198766090e2895f1fb37473d5212b2bed31c15b0745dc4
ToppCellproximal-Epithelial-Proximal_Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.14e-06198766594b46e811f112d98879b59fdd0cfb068fc07f94
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7

1.17e-06199766b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.17e-061997662de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell(10)_Ciliated|World / shred by cell type by condition

CCDC170 DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

1.21e-062007661b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CCDC170 DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.21e-06200766bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7

1.21e-062007667cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC170 DNAH3 DNAH12 DNAAF6 CFAP44 DNAH7

1.21e-062007668441e289377215a6877640946fe3f6de1f456502
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNAH12 CFAP44 FAM186B CCDC116

7.09e-06727647877184d5c9dd6d96476d71e7504e58c0b4d0f26
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DNAH12 DNAAF6 CFAP44 DNAH7 CCDC39

9.62e-061667654b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7

1.05e-0516976514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7

1.18e-05173765c3762655caa79ac4879876f470d32578a3c93b01
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH3 DNAH12 DNAH7 CCDC39

1.31e-05177765c38138fb5ad9766c2d240811210c854338cd612e
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.35e-05178765255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

CCDC170 DNAH12 DNAH17 DNAH7 CCDC39

1.35e-05178765d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT6A GXYLT1 CKAP2 PLK1 NUP160

1.39e-051797654166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC170 DNAH3 DNAH12 CFAP44 DNAH7

1.42e-051807651f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CCDC170 DNAH3 DNAH12 DNAAF6 CCDC39

1.46e-051817655a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

CCDC170 DNAH3 DNAH12 DNAAF6 CCDC39

1.46e-05181765a4e891603645f694687e68e585744ddc1a3c8697
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CCDC170 DNAH3 DNAH12 DNAH7 CCDC39

1.50e-05182765fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CCDC170 DNAH12 CFAP44 DNAH7 CCDC39

1.50e-05182765e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHANK1 ATRNL1 DOCK10 GRID2 TNXB

1.54e-051837657eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.54e-05183765b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.54e-05183765cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH3 DNAH12 CFAP44 CCDC39

1.58e-05184765797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC170 DNAH3 DNAH12 CFAP44 CCDC39

1.58e-0518476577d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATRNL1 GRID2 RUNX1T1 CCDC171 TNXB

1.62e-051857656712512100ccef456d2e2bd201d0987986c92ac9
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 DNAH12 DNAAF6 DNAH7 CCDC39

1.62e-051857654fc7113d3dadc716ec5a8e62b58543cc00ce5b16
DrugKetanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; MCF7; HT_HG-U133A

GRK2 ATRX MTOR MAPKAPK2 MAPKAPK3 GAN CFAP44

4.45e-061987674995_DN
Diseaseintellectual disability (implicated_via_orthology)

ZC3H14 ANK2 ATRX RB1

3.47e-0575724DOID:1059 (implicated_via_orthology)
Diseasepsoriatic arthritis

MFSD4B TNXB BAG6 CCDC116

6.22e-0587724EFO_0003778
DiseaseFEV/FEC ratio

STX2 LIMK1 DNAH12 DST DOCK9 SYNE2 RUNX1T1 CCDC171 CLEC16A TNXB CYFIP2

1.82e-0412287211EFO_0004713
DiseaseCarcinoma, Small Cell

RB1 MTOR

2.09e-049722C0262584
DiseaseColorectal Carcinoma

SHANK1 DNAH3 ANK2 LAMA1 GRID2 ABCC2 RUNX1T1 CAMSAP2

3.09e-04702728C0009402
DiseaseNeoplasm of uncertain or unknown behavior of bladder

RB1 MTOR

6.04e-0415722C0496930
DiseaseBenign neoplasm of bladder

RB1 MTOR

6.04e-0415722C0154017
DiseaseCarcinoma in situ of bladder

RB1 MTOR

6.04e-0415722C0154091
DiseaseCarcinoma of bladder

RB1 MTOR

8.76e-0418722C0699885
Diseaseend stage renal disease (implicated_via_orthology)

MTOR ABCC2

1.08e-0320722DOID:783 (implicated_via_orthology)
DiseaseObsessive-compulsive trait

SH3GL2 GRID2

1.20e-0321722HP_0008770
Diseaseaspartate aminotransferase measurement

PIK3AP1 DNAJC13 MTOR HECTD4 NIPAL1 ABCC2 CLEC16A NUP160

1.59e-03904728EFO_0004736
DiseaseSquamous cell carcinoma of esophagus

RB1 ABCC2 TNXB

1.64e-0395723C0279626
Diseaseserum gamma-glutamyl transferase measurement

PIK3AP1 EYS ATRX NUAK1 HECTD4 ABCC2 CCDC171 CYFIP2

1.71e-03914728EFO_0004532
Diseasecorpus callosum central volume measurement

NUAK1 CLEC16A

2.13e-0328722EFO_0010296
Diseaselung small cell carcinoma (is_implicated_in)

ATRX MTOR

2.13e-0328722DOID:5409 (is_implicated_in)
Diseasestimulant use measurement

EYS RB1

2.13e-0328722EFO_0600076
Diseaseosteoarthritis

GRK2 RAPH1 ATRNL1 GRID2

2.15e-03222724MONDO_0005178
DiseaseR-6-hydroxywarfarin to R-warfarin ratio measurement

EYS DNAH17 GAN

2.24e-03106723EFO_0803333

Protein segments in the cluster

PeptideGeneStartEntry
IEIMEMKHKSETDTS

CCT6A

191

P40227
LETVVEKATERMAAM

CCDC116

86

Q8IYX3
MKQRTSSMERHEETL

CCDC7

626

Q96M83
HMIRDIQTLLSRMET

BAG6

171

P46379
RIMTLEKEMTSHRSH

CCDC171

1216

Q6TFL3
AEEEMRASLKTLHRM

GTPBP2

116

Q9BX10
LEEKHRECLSSMVTM

FAM186B

771

Q8IYM0
ETVDMLKSHIKEELM

PIK3AP1

396

Q6ZUJ8
EMTKTIHKMEETVRQ

CFAP44

1686

Q96MT7
TKDKHEIDRMTLTMA

GRK2

396

P25098
MEERTEEIKVHKTML

CCDC39

596

Q9UFE4
EEMRHTIVDILTMKS

CKAP2

496

Q8WWK9
MPSSHIVLKEETRML

LINC00301

1

Q8NCQ3
VMESMLKSEEERLSI

RB1

456

P06400
LVIRVHMSDDSSKTM

RAPH1

271

Q70E73
AVSVMDSMIHDILDR

H2BW2

81

P0C1H6
TERIEETMSVRELMK

ANK2

1981

Q01484
DVKEEMTSALATMRV

MAPKAPK2

351

P49137
VKEEMTSALATMRVD

MAPKAPK3

331

Q16644
MTDKSIVILSLMVFH

EYS

1

Q5T1H1
HDMITTERAKMERTV

RUNX1T1

476

Q06455
SMITESMAIKVLEIL

DST

1651

Q03001
EDMVHAILEKLMTLV

FSIP2

821

Q5CZC0
KMITTLFDTMRIEEL

GRID2

206

O43424
RLEETMTMLKSAIIF

GXYLT1

126

Q4G148
RSTEHEMAKSEIRMI

HERC6

396

Q8IVU3
TIDVHARDVVMDMIK

DNAH12

1166

Q6ZR08
IAHRLHTIMDSDKVM

ABCC2

1491

Q92887
ILTDHILETKEPSMM

CYFIP2

671

Q96F07
DVMEEMVVSCVIKHL

HECTD4

901

Q9Y4D8
MIETNDTMRHSIIET

MFSD4B

456

Q5TF39
LTLVERMDEEFTKIM

EIF3CL

446

B5ME19
DSTMVDVRVMKKRAH

ATRX

1791

P46100
SMRKVLETVFDEVIM

GYG1

46

P46976
IRTVLMATAQMKEHE

DOCK10

1661

Q96BY6
IRTVLMATAQMKEHE

DOCK9

1576

Q9BZ29
TEMELLEVSQHIKMR

CABP4

166

P57796
TMMLKSSEVLVETLE

DNAH17

1436

Q9UFH2
MKIMTICTIDVHARD

DNAH17

1751

Q9UFH2
SFRKREVMTTEEMKH

DNAH3

806

Q8TD57
DTEIRKVHMKDVMSA

GAN

206

Q9H2C0
RELISKHMKTIVEME

CUL3

266

Q13618
MRSVMQDKHVLTVVT

DNAH7

1021

Q8WXX0
AHIMELDSRDVVMII

ATRNL1

416

Q5VV63
DKVSTTVREMMLEHF

DNAJC13

1936

O75165
EITISLLKREMDQTM

CMPK1

66

P30085
HEMEAKASRETIMRL

CCDC170

221

Q8IYT3
ETLEITMTMKRELDI

DNAAF6

196

Q9NQM4
DHISDEISIMTLRMF

FHIP2A

461

Q5W0V3
KEHLKVVVMSATMEL

DHX40

201

Q8IX18
LGESKEHMESRMVTE

SDE2

301

Q6IQ49
LLASEMVHLRMKLEE

CAMSAP2

756

Q08AD1
MESVHMKIEEKITLT

ARCN1

271

P48444
EEEVTSLHEMEMKLR

NIPAL1

191

Q6NVV3
TEIEDSHTLVTVMMK

TBRG4

216

Q969Z0
HTVMEVLREHKDSVM

MTOR

2401

P42345
EERMVHKVTMDTVKI

MROH2A

496

A6NES4
LMSHEKLPVRTETAM

GINS3

26

Q9BRX5
MKADLTRHVLVEDVM

SYNE2

5871

Q8WXH0
IERLQMSITEIMEKT

LAMA1

1661

P25391
EEIAMLRLELDTMKH

POTEJ

616

P0CG39
DMVHIRREIEIMSSL

NUAK1

96

O60285
VIEFITEMTHKAMSI

TAF13

61

Q15543
RLIEESVTVDMSVIM

NUP160

611

Q12769
IMKLETSIRELHEMF

STX2

201

P32856
DRVMKLITSDVLEEM

SNAPC1

166

Q16533
VKVVMVTRHPDMDEA

SHANK1

751

Q9Y566
IEMVIMERSKLSELA

CLEC16A

436

Q2KHT3
MERKVDVTSRAVMEI

SH3GL2

36

Q99962
DVTSRAVMEIMTKTI

SH3GL2

41

Q99962
TIEGMRMHLLEETTV

TNXB

751

P22105
SRSALKMIMEELHDV

VPS41

666

P49754
MEDIKESIETMRTRL

TMED1

151

Q13445
LSEMDSVLMKIHTSL

PIGG

236

Q5H8A4
DILMEKLSVMLSTRT

GTF3C1

256

Q12789
MESMVHADTRSFILK

ZC3H14

456

Q6PJT7
EKMSMEISIHRSLAH

PLK1

96

P53350
VTHRETGEVMVMKEL

LIMK1

356

P53667