Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	antigen binding	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-74	6.93e-08	190	106	10	GO:0003823
GeneOntologyMolecularFunction	recombination hotspot binding	PRDM7 PRDM9	2.79e-05	2	106	2	GO:0010844
GeneOntologyMolecularFunction	acetyl-CoA binding	PANK3 TAF1	1.66e-04	4	106	2	GO:1905502
GeneOntologyBiologicalProcess	immunoglobulin mediated immune response	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 IGHV3-74	1.98e-09	235	102	12	GO:0016064
GeneOntologyBiologicalProcess	B cell mediated immunity	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 IGHV3-74	3.02e-09	244	102	12	GO:0019724
GeneOntologyBiologicalProcess	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	KLHL6 CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 IGHV3-74	4.61e-07	462	102	13	GO:0002460
GeneOntologyBiologicalProcess	lymphocyte mediated immunity	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 IGHV3-74	2.25e-06	449	102	12	GO:0002449
GeneOntologyBiologicalProcess	leukocyte mediated immunity	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 IGHV3-74	2.75e-05	576	102	12	GO:0002443
GeneOntologyBiologicalProcess	immune effector process	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 CEBPB IGHV3-21 IGHV3-11 IGHV3-7 MSH6 IGHV3-30-5 IGHV3-30-3 PRKDC IGHV3-74	8.38e-05	859	102	14	GO:0002252
GeneOntologyBiologicalProcess	positive regulation of reciprocal meiotic recombination	PRDM7 PRDM9	1.44e-04	4	102	2	GO:0010845
GeneOntologyBiologicalProcess	regulation of reciprocal meiotic recombination	PRDM7 PRDM9	1.44e-04	4	102	2	GO:0010520
GeneOntologyCellularComponent	immunoglobulin complex	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-74	1.15e-08	166	105	10	GO:0019814
Domain	Bromodomain_CS	BRD3 BRDT TAF1 BRD1	8.26e-06	26	94	4	IPR018359
Domain	MKRN1_C	MKRN3 MKRN1	2.51e-05	2	94	2	PF15815
Domain	MKRN1_C	MKRN3 MKRN1	2.51e-05	2	94	2	IPR031644
Domain	BROMODOMAIN_1	BRD3 BRDT TAF1 BRD1	3.50e-05	37	94	4	PS00633
Domain	Bromodomain	BRD3 BRDT TAF1 BRD1	3.90e-05	38	94	4	PF00439
Domain	BROMODOMAIN_2	BRD3 BRDT TAF1 BRD1	5.28e-05	41	94	4	PS50014
Domain	Bromodomain	BRD3 BRDT TAF1 BRD1	5.82e-05	42	94	4	IPR001487
Domain	BROMO	BRD3 BRDT TAF1 BRD1	5.82e-05	42	94	4	SM00297
Domain	-	BRD3 BRDT TAF1 BRD1	5.82e-05	42	94	4	1.20.920.10
Domain	BET	BRD3 BRDT	1.49e-04	4	94	2	PF17035
Domain	NET_dom	BRD3 BRDT	1.49e-04	4	94	2	IPR027353
Domain	NET	BRD3 BRDT	1.49e-04	4	94	2	PS51525
Domain	PWWP	ZCWPW2 MSH6 BRD1	2.03e-04	23	94	3	PF00855
Domain	PWWP_dom	ZCWPW2 MSH6 BRD1	2.03e-04	23	94	3	IPR000313
Domain	PWWP	ZCWPW2 MSH6 BRD1	2.31e-04	24	94	3	PS50812
Domain	eIF5C	BZW2 BZW1	5.18e-04	7	94	2	SM00515
Domain	W2	BZW2 BZW1	5.18e-04	7	94	2	PF02020
Domain	W2	BZW2 BZW1	5.18e-04	7	94	2	PS51363
Domain	W2_domain	BZW2 BZW1	5.18e-04	7	94	2	IPR003307
Domain	SSXRD	PRDM7 PRDM9	6.88e-04	8	94	2	PF09514
Domain	SSXRD_motif	PRDM7 PRDM9	6.88e-04	8	94	2	IPR019041
Domain	KRAB_RELATED	PRDM7 PRDM9	1.34e-03	11	94	2	PS50806
Domain	TPR_REGION	SGTB TTC6 FEM1B CDC16 PRKDC	1.48e-03	165	94	5	PS50293
Domain	TPR	SGTB TTC6 FEM1B CDC16 PRKDC	1.48e-03	165	94	5	PS50005
Domain	Krueppel-associated_box-rel	PRDM7 PRDM9	1.89e-03	13	94	2	IPR003655
Domain	-	BZW2 BZW1	2.52e-03	15	94	2	1.25.40.180
Domain	PI3/4_kinase_CS	PIK3CA PRKDC	2.52e-03	15	94	2	IPR018936
Domain	MIF4-like	BZW2 BZW1	2.52e-03	15	94	2	IPR016021
Domain	-	PIK3CA PRKDC	2.87e-03	16	94	2	1.10.1070.11
Domain	PI3Kc	PIK3CA PRKDC	2.87e-03	16	94	2	SM00146
Domain	PI3_PI4_kinase	PIK3CA PRKDC	3.64e-03	18	94	2	PF00454
Domain	PI3_4_KINASE_1	PIK3CA PRKDC	3.64e-03	18	94	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CA PRKDC	3.64e-03	18	94	2	PS00916
Domain	PI3/4_kinase_cat_dom	PIK3CA PRKDC	3.64e-03	18	94	2	IPR000403
Domain	PI3_4_KINASE_3	PIK3CA PRKDC	3.64e-03	18	94	2	PS50290
Domain	BTB	KLHL6 ZBTB47 KBTBD4 ZBTB40	4.33e-03	131	94	4	PF00651
Domain	PWWP	MSH6 BRD1	4.49e-03	20	94	2	SM00293
Domain	C2	MCTP1 PIK3CA CADPS PLCB4	5.08e-03	137	94	4	SM00239
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 PIK3CA IGHV3-74	1.40e-12	45	74	9	MM14912
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.21e-12	35	74	8	MM17219
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 PIK3CA IGHV3-74	1.14e-11	56	74	9	MM14815
Pathway	REACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.11e-11	39	74	8	MM17212
Pathway	REACTOME_FCGR_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.25e-10	48	74	8	MM17214
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.87e-10	53	74	8	MM15716
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	3.35e-10	54	74	8	MM14655
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	4.93e-10	84	74	9	MM14653
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	6.07e-10	58	74	8	MM14914
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.04e-10	60	74	8	MM14872
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.04e-10	60	74	8	MM14913
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 PIK3CA IGHV3-74	7.65e-09	114	74	9	MM14814
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PIK3CA	8.36e-08	71	74	7	M27203
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.42e-08	107	74	8	MM14915
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 PIK3CA IGHV3-74	8.43e-08	150	74	9	MM14889
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 PIK3CA IGHV3-74	1.32e-07	158	74	9	MM14812
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PIK3CA	2.28e-07	82	74	7	M27110
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	4.04e-07	131	74	8	MM15717
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	5.09e-07	135	74	8	MM14781
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	7.52e-07	61	74	6	M27581
Pathway	REACTOME_FCGR_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.57e-06	69	74	6	M27108
Pathway	REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.57e-06	69	74	6	M27150
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.86e-06	71	74	6	M1078
Pathway	REACTOME_COMPLEMENT_CASCADE	CFH IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.29e-06	115	74	7	M19752
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	3.76e-06	80	74	6	M6121
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	5.74e-06	86	74	6	M601
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	5.74e-06	86	74	6	M27206
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	6.14e-06	87	74	6	M27205
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PIK3CA PICK1	7.72e-06	194	74	8	M16312
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PIK3CA	9.74e-06	143	74	7	M27107
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.02e-05	95	74	6	M29842
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.22e-05	98	74	6	M27152
Pathway	REACTOME_PARASITE_INFECTION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	3.20e-05	116	74	6	M29843
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PIK3CA	5.31e-05	186	74	7	M27175
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	7.19e-05	134	74	6	M29840
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	7.81e-05	136	74	6	M27207
Pathway	REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.55e-04	154	74	6	M39007
Pathway	REACTOME_HEMOSTASIS	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 DGKH SERPINB6 PIK3CA IGHV3-74	1.80e-04	571	74	11	MM14472
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.33e-04	166	74	6	M608
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	4.80e-04	190	74	6	M8240
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SPTBN1 TSC2 IGF2R IGHV3-74	5.10e-04	645	74	11	MM15232
Pathway	REACTOME_SARS_COV_INFECTIONS	IGHV3-48 NLRP12 IGHV3-33 IGHV3-30 IGHV3-23 MAN2A1 IGHV3-11 IGHV3-7 MGAT4C	7.73e-04	471	74	9	M39009
Pathway	REACTOME_HEMOSTASIS	KCNMB2 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 DGKH SERPINB6 PIK3CA PICK1	7.82e-04	679	74	11	M8395
Pathway	REACTOME_LEISHMANIA_INFECTION	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	1.01e-03	219	74	6	M29836
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 MKRN1 PIK3CA CDC16 IGHV3-74	1.25e-03	719	74	11	MM14540
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	MKRN1 TSC2	1.73e-03	12	74	2	MM14777
Pubmed	1.3 A X-ray structure of an antibody Fv fragment used for induced membrane-protein crystallization.	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	3.59e-17	15	106	8	12657787
Pubmed	Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.76e-15	22	106	8	2499654
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MKRN3 CFH DPYSL2 SGTB CNST ENPP2 SPTBN1 USP25 ZBTB47 CUL9 SPOCK2 TSC2 ADAMTS8 DZIP1 LRP1B ME3 STX1A DST CADPS PRKDC TAF1 PICK1	4.09e-11	1285	106	22	35914814
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.01e-10	77	106	8	15608191
Pubmed	Molecular analysis of spontaneous somatic mutants.	IGHV3-48 IGHV3-21 IGHV3-11 IGHV3-7	4.07e-10	5	106	4	401950
Pubmed	The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.31e-08	91	106	7	9841928
Pubmed	Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region.	IGHV3-48 IGHV3-21 IGHV3-11 IGHV3-7	2.41e-07	18	106	4	6788376
Pubmed	Histone recognition and large-scale structural analysis of the human bromodomain family.	BRD3 BRDT BRD1	9.55e-07	7	106	3	22464331
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRD3 BRDT TAF1 BRD1 DNAH9	3.48e-06	75	106	5	25593309
Pubmed	Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus.	IGHV3-48 IGHV3-23 IGHV3-11 IGHV3-7	6.18e-06	39	106	4	8490662
Pubmed	Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation.	BZW2 BZW1	9.20e-06	2	106	2	36333315
Pubmed	Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions.	IGHV3-23 IGHV3-7	9.20e-06	2	106	2	4522793
Pubmed	Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.	BZW2 BZW1	9.20e-06	2	106	2	29470543
Pubmed	PRDM9 losses in vertebrates are coupled to those of paralogs ZCWPW1 and ZCWPW2.	ZCWPW2 PRDM9	2.76e-05	3	106	2	35217607
Pubmed	Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism.	BZW2 BZW1	2.76e-05	3	106	2	34260931
Pubmed	mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.	TSC2 PRKDC	2.76e-05	3	106	2	24096482
Pubmed	Differential chromatin packaging of genomic imprinted regions between expressed and non-expressed alleles.	MKRN3 IGF2R	2.76e-05	3	106	2	11115847
Pubmed	Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1.	SPTBN1 PKDCC	2.76e-05	3	106	2	38683846
Pubmed	Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A.	SLC6A9 STX1A	2.76e-05	3	106	2	10722844
Pubmed	Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169.	IGHV3-48 IGHV3-21	2.76e-05	3	106	2	33036024
Pubmed	Calcium-dependent activator protein for secretion 1 (CAPS1) binds to syntaxin-1 in a distinct mode from Munc13-1.	STX1A CADPS	2.76e-05	3	106	2	23801330
Pubmed	Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.	BRD3 BRDT	2.76e-05	3	106	2	28945351
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	MKRN3 DPYSL2 IKZF3 BEND5 TSC2 STX1A DHCR7 ALG13	3.34e-05	402	106	8	24722188
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	DPYSL2 SPTBN1 LRPPRC IGF2R DHCR7 PYGB PRKDC	4.99e-05	312	106	7	37120454
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 SPOCK2 FEM1B DST CADPS	5.06e-05	130	106	5	12421765
Pubmed	Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice.	CEBPB BZW1	5.50e-05	4	106	2	37828427
Pubmed	Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer.	PIK3CA PRKDC	5.50e-05	4	106	2	31112530
Pubmed	Expression of BET genes in testis of men with different spermatogenic impairments.	BRD3 BRDT	5.50e-05	4	106	2	22035730
Pubmed	Pin1 Regulates IL-5 Induced Eosinophil Polarization and Migration.	BZW2 BZW1	5.50e-05	4	106	2	33494375
Pubmed	Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes.	PRDM7 PRDM9	5.50e-05	4	106	2	18231586
Pubmed	Genomic analysis of mouse retinal development.	PANK3 GPR37 CUL9 SLC25A37 FEM1B SLC6A9 STX1A DST CADPS PTPRS PPIP5K1 PRKDC	5.84e-05	1006	106	12	15226823
Pubmed	Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.	BZW2 BZW1	9.15e-05	5	106	2	27325740
Pubmed	Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair.	MSH6 PRKDC	9.15e-05	5	106	2	21075794
Pubmed	Identification of LRP1B-interacting proteins and inhibition of protein kinase Calpha-phosphorylation of LRP1B by association with PICK1.	LRP1B PICK1	9.15e-05	5	106	2	19071120
Pubmed	Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.	PIK3CA PRKDC	9.15e-05	5	106	2	15664519
Pubmed	The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death.	GPR37 PICK1	1.37e-04	6	106	2	24749734
Pubmed	TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.	CEBPB TSC2	1.37e-04	6	106	2	27593484
Pubmed	DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.	TSC2 PIK3CA	1.37e-04	6	106	2	21252315
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SPTBN1 MKRN1 DZIP1 LRPPRC DST SH3GLB1 ZBTB40 TAF1	1.46e-04	497	106	8	23414517
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL9 BRD3 MSH6 MCTP1 BRDT ZNRF3 COQ8A CADPS CDC16 TAF1 BRD1 ALG13	1.55e-04	1116	106	12	31753913
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DPYSL2 SPTBN1 CUL9 MSH6 LRPPRC IGF2R DST PYGB PRKDC	1.79e-04	653	106	9	22586326
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SPTBN1 MSH6 LRPPRC DST DHCR7 PYGB RBM46 PRKDC BZW1 ALG13	1.84e-04	807	106	10	30575818
Pubmed	The yin-yang of PR-domain family genes in tumorigenesis.	PRDM7 PRDM9	1.91e-04	7	106	2	10668202
Pubmed	Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.	TSC2 PIK3CA	1.91e-04	7	106	2	24529379
Pubmed	Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci.	IGF2R PIK3CA	1.91e-04	7	106	2	21047779
Pubmed	TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder.	MSH6 IGF2R	1.91e-04	7	106	2	17676485
Pubmed	IκB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway.	TSC2 PIK3CA	1.91e-04	7	106	2	23778976
Pubmed	Myosin-reactive autoantibodies in rheumatic carditis and normal fetus.	IGHV3-48 IGHV3-30	1.91e-04	7	106	2	9614934
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	PARP2 SPTBN1 BRD3 LRPPRC CDC16 PRKDC TAF1	2.11e-04	394	106	7	27248496
Pubmed	Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.	TSC2 PIK3CA	2.55e-04	8	106	2	20622004
Pubmed	The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis.	MKRN3 IGF2R	2.55e-04	8	106	2	12482959
Pubmed	SET domains and histone methylation.	PRDM7 PRDM9	2.55e-04	8	106	2	14675547
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	ARSK SPTBN1 BRD3 LRPPRC PTPRS	2.92e-04	189	106	5	29449217
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	DPYSL2 BZW2 MSH6 LRPPRC COQ8A CDC16 PYGB BZW1	3.26e-04	560	106	8	35241646
Pubmed	Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina.	SLC6A9 STX1A	3.27e-04	9	106	2	17729288
Pubmed	Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.	CFH CNDP1	3.27e-04	9	106	2	20299368
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	MAN2A1 MGAT4C ALG13	3.80e-04	46	106	3	2649653
Pubmed	The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.	TSC2 PIK3CA	4.08e-04	10	106	2	15249583
Pubmed	Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.	SPTBN1 ZBTB40	4.08e-04	10	106	2	20554715
Pubmed	SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.	STX1A CADPS	4.08e-04	10	106	2	21040848
Pubmed	CAPS1 regulates catecholamine loading of large dense-core vesicles.	STX1A CADPS	4.08e-04	10	106	2	15820695
Pubmed	Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.	ME3 STX1A PYGB	4.58e-04	49	106	3	20471030
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DPYSL2 IGHV3-30 SPTBN1 SPOCK2 BRD3 ZCCHC4 MSH6 LRPPRC DST DHCR7 PRKDC	4.72e-04	1082	106	11	38697112
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	SPOCK2 ADAMTS8 STX1A PYGB PICK1	4.73e-04	210	106	5	16537572
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	CUL9 LRPPRC DST COQ8A CDC16	4.94e-04	212	106	5	33853758
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTBN1 TAF1	4.97e-04	11	106	2	17607528
Pubmed	Genomic imprinting in Dicer1-hypomorphic mice.	MKRN3 IGF2R	4.97e-04	11	106	2	16575173
Pubmed	The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.	STX1A CADPS	4.97e-04	11	106	2	25374362
Pubmed	7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome.	CEBPB DHCR7	4.97e-04	11	106	2	36111785
Pubmed	Multiple genetic loci for bone mineral density and fractures.	SPTBN1 ZBTB40	4.97e-04	11	106	2	18445777
Pubmed	Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle.	MAN2A1 IGF2R	4.97e-04	11	106	2	7642711
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	KLHL6 SPTBN1 SLC25A37 DST KCNJ4 PRKDC	5.54e-04	332	106	6	37433992
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SPTBN1 MSH6 SERPINB6 PRKDC TAF1 BZW1	5.54e-04	332	106	6	32786267
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	DPYSL2 SPTBN1 TTC6 LRPPRC PRKDC DNAH9	5.63e-04	333	106	6	32665550
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	SPTBN1 BRD3 MSH6 LRPPRC PRKDC	5.72e-04	219	106	5	31353912
Pubmed	Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate.	SLC6A9 STX1A	5.95e-04	12	106	2	21743471
Pubmed	Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.	TSC2 PIK3CA	5.95e-04	12	106	2	20665729
Pubmed	The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops.	IGHV3-21 IGHV3-74	5.95e-04	12	106	2	1404388
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	ENPP2 STX1A SH3GLB1 CADPS	6.51e-04	128	106	4	30995482
Pubmed	Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development.	SLC6A9 STX1A	7.02e-04	13	106	2	17724084
Pubmed	BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.	CFH DGKH DNAH9	7.14e-04	57	106	3	27433848
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DPYSL2 CNST SPTBN1 LRP1B LRPPRC STX1A SERPINB6 CADPS CDC16 DHCR7 PYGB	7.22e-04	1139	106	11	36417873
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KLHL6 TSC2 SPG11 SLC25A37 SLC6A9 MSH6 SERPINB6 PIK3CA CDC16 ZBTB40 BZW1 BRD1	7.33e-04	1327	106	12	32694731
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	DPYSL2 SPTBN1 MSH6 SULT1C2 PRKDC	7.86e-04	235	106	5	30258100
Pubmed	A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.	COQ8A PYGB PARPBP	7.90e-04	59	106	3	15010206
Pubmed	Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.	SLC6A9 STX1A	8.18e-04	14	106	2	14625556
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GPR37 SPTBN1 SPG11 BRD3 TTC6 RBM46 PLCB4	8.42e-04	497	106	7	36774506
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	SPTBN1 MSH6 LRPPRC IGF2R DHCR7 PRKDC BZW1 ALG13	9.25e-04	657	106	8	36180527
Pubmed	Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.	DPYSL2 CUL9 LRPPRC IGF2R PYGB	1.02e-03	249	106	5	30097533
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	USP25 FEM1B	1.07e-03	16	106	2	28619731
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	PRDM9 TDRD12	1.07e-03	16	106	2	29878059
Pubmed	Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina.	SLC6A9 STX1A	1.07e-03	16	106	2	17301087
Pubmed	Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler.	PARP2 PRKDC	1.07e-03	16	106	2	19666485
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DPYSL2 CEBPB EAPP BRD3 MSH6 CDC16 PYGB PRKDC TAF1 BZW1	1.08e-03	1014	106	10	32416067
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CFH MAN2A1 FETUB PTPRS CNDP1	1.17e-03	257	106	5	16335952
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	SGTB USP25 TSC2 SH3GLB1	1.17e-03	150	106	4	32423001
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	MSH6 PIK3CA PRKDC	1.35e-03	71	106	3	28319113
Pubmed	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	DGKH PYGB	1.36e-03	18	106	2	24068962
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	DPYSL2 SPTBN1 BRD3 MSH6 DST	1.48e-03	271	106	5	25737280
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	BZW2 SPTBN1 LRPPRC IGF2R DST DHCR7 PRKDC BZW1	1.49e-03	708	106	8	39231216
Cytoband	14q32.33	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-74	1.57e-10	228	106	10	14q32.33
Cytoband	Ensembl 112 genes in cytogenetic band chr14q32	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	5.32e-05	566	106	8	chr14q32
Cytoband	2p21	SPTBN1 PKDCC LRPPRC	3.91e-04	61	106	3	2p21
GeneFamily	Immunoglobulin heavy locus at 14q32.33	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-30-5 IGHV3-30-3 IGHV3-74	9.68e-09	187	80	10	349
GeneFamily	LIM zinc finger domain containing\|LIM domain containing	LIMS4 LIMS3	1.15e-04	4	80	2	1163
GeneFamily	PWWP domain containing	ZCWPW2 MSH6 BRD1	1.21e-04	22	80	3	1147
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM7 PRDM9	2.52e-03	17	80	2	1197
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL6 ZBTB47 KBTBD4 ZBTB40	2.95e-03	134	80	4	861
Coexpression	XU_CREBBP_TARGETS_DN	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	5.67e-11	56	104	8	MM642
Coexpression	RASHI_RESPONSE_TO_IONIZING_RADIATION_6	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 BRD1 IGHV3-74	2.90e-09	132	104	9	MM996
Coexpression	YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	7.53e-09	102	104	8	MM872
Coexpression	GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP	AMD1 SGTB BZW2 DGKH DZIP1 PLEKHG2 ZBTB40	6.22e-06	174	104	7	M380
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN	LANCL3 DPYSL2 CEBPB SPOCK2 PTPRS PYGB PLCB4	8.66e-06	183	104	7	M8886
Coexpression	GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	CNST BEND5 BZW2 SPTBN1 CUL9 BRD3 LRPPRC	1.40e-05	197	104	7	M6512
Coexpression	SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_DN	IGHV3-48 IGHV3-7 IGHV3-74	3.27e-05	16	104	3	M41742
Coexpression	SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	AMD1 IGHV3-33 IGHV3-23 IGHV3-7 SLC25A37 MSH6 PYGB PRKDC	4.60e-05	324	104	8	M2700
Coexpression	SMID_BREAST_CANCER_BASAL_UP	AMD1 IGHV3-33 IGHV3-23 IGHV3-7 GPR37 DZIP1 SLC25A37 MSH6 PYGB PLCB4 TDRD12	6.53e-05	662	104	11	M8124
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.21e-06	163	102	8	Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.06e-06	175	102	8	Arv_SC-H9hpx_500_K3
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	5.51e-06	266	102	9	Arv_SC-hpx_blastocyst_1000_K2
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#4	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.35e-05	244	102	8	Arv_SC-H9hpx_1000_K4
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	2.92e-05	183	102	7	Arv_SC_fibroblast_1000_K5
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	2.92e-05	183	102	7	Arv_SC-HD_1000_K3
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.27e-05	126	102	6	Arv_SC-HD_500_K2
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#3	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	5.68e-05	139	102	6	Arv_SC_fibroblast_500_K3
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.77e-11	191	104	10	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	3.67e-10	177	104	9	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	3.67e-10	177	104	9	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	3.67e-10	177	104	9	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	6.87e-10	190	104	9	79ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	6.87e-10	190	104	9	18762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	7.89e-10	193	104	9	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 IGHV3-48 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.25e-10	194	104	9	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.45e-10	197	104	9	2662138671262b30508c5759038bcdcfe6551696
ToppCell	Control-Control-Lymphocyte-B-Plasmablast\|Control / Disease, condition lineage and cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	1.03e-09	199	104	9	c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCell	3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasma_cells\|bone_marrow / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 SLC6A9 IGHV3-74	8.36e-09	175	104	8	51301f3f44d3e88397f367cedd1e2abaa2be4c6f
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.74e-09	176	104	8	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	8.74e-09	176	104	8	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.14e-09	177	104	8	c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.14e-09	177	104	8	111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.55e-09	178	104	8	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.98e-09	179	104	8	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9	9.98e-09	179	104	8	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	9.98e-09	179	104	8	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.19e-08	183	104	8	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.29e-08	185	104	8	0fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.29e-08	185	104	8	79edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.29e-08	185	104	8	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.29e-08	185	104	8	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-33 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 SLC6A9 IGHV3-74	1.46e-08	188	104	8	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	cellseq2-Immune-Lymphocytic_B-Lymphocytic_B\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KLHL6 IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	1.66e-08	191	104	8	17746a32f723c078aba1f7e320b0e3f1ab8bf5c6
ToppCell	cellseq2-Immune-Lymphocytic_B\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KLHL6 IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	1.66e-08	191	104	8	c2c450df810f83163987cd0f7ed9b50025cd3de1
ToppCell	COVID-19-Lymphoid-Plasma,_B_cells\|COVID-19 / Condition, Lineage and Cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 PARPBP IGHV3-74	1.80e-08	193	104	8	bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 BEND5	1.80e-08	193	104	8	bcda1fb3db7d4c276e3370250a2b79fedd807fc5
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 BEND5	1.80e-08	193	104	8	befab58da635723db4f9270d087afa981fc45bf1
ToppCell	Control-B_cell-B_cell\|Control / Disease group,lineage and cell class （2021.01.30）	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 BEND5	1.80e-08	193	104	8	d43099c0b8ca68048d6497c4db89d6d5155375f9
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 BEND5	1.80e-08	193	104	8	ba826e6e035e48e1b497af1081c43339b0019e76
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.80e-08	193	104	8	34f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.87e-08	194	104	8	6ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	1.95e-08	195	104	8	f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.02e-08	196	104	8	e9fe5090452ffdde4bb81b62d57037d823281d00
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.02e-08	196	104	8	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.02e-08	196	104	8	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.02e-08	196	104	8	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.11e-08	197	104	8	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	2.11e-08	197	104	8	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	2.19e-08	198	104	8	79c690d21d3420d0bb1a3b3b4ea2c9aa3810a219
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	KLHL6 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 IGHV3-74	1.09e-07	162	104	7	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	KLHL6 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-21 IGHV3-11 IGHV3-74	1.09e-07	162	104	7	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.34e-07	167	104	7	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.34e-07	167	104	7	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.46e-07	169	104	7	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.52e-07	170	104	7	ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.52e-07	170	104	7	d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	1.52e-07	170	104	7	52787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 IGHV3-74	1.71e-07	173	104	7	7e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.07e-07	178	104	7	6f50e2ee66bd9dc12fd3c9ea70e6d50ff76b02e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-74	2.07e-07	178	104	7	f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-74	2.07e-07	178	104	7	a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.07e-07	178	104	7	b132605f237e766a21042b9a65a564d64c4fec10
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.07e-07	178	104	7	99cd5e517855f1a2d6d75fb2d439751f884862c1
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	2.32e-07	181	104	7	f7b08f662eb77ee7a777c6525ddc3195046aaf65
ToppCell	Mild_COVID-19-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.50e-07	183	104	7	dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.59e-07	184	104	7	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.59e-07	184	104	7	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.69e-07	185	104	7	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	COVID-19-lung-Plasmablasts\|lung / Disease (COVID-19 only), tissue and cell type	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 PARPBP	2.79e-07	186	104	7	81caf67da9fed09c77b7ddcab9b0b8e4fab2de97
ToppCell	Mild_COVID-19-B_cell-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	2.79e-07	186	104	7	855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7 IGHV3-74	3.00e-07	188	104	7	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	cellseq2-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KLHL6 IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.00e-07	188	104	7	33360f1c30315d9772731c9067834dc059172b79
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DZIP1 PLEKHG2 LRP1B DST SULT1C2 PLCB4 CACNA2D3	3.11e-07	189	104	7	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DZIP1 PLEKHG2 LRP1B DST SULT1C2 PLCB4 CACNA2D3	3.11e-07	189	104	7	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21	3.58e-07	193	104	7	5c5543e7c83ecea44d23521246592c0301044173
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AMD1 DPYSL2 GPR37 ENPP2 DST KEL CNDP1	3.58e-07	193	104	7	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	Control-Lymphoid-Plasma,_B_cells\|Control / Condition, Lineage and Cell class	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.71e-07	194	104	7	31fff4361ebed6308b1e6b2b705ee6e0a695bd0c
ToppCell	Control-B_cell\|Control / Disease group,lineage and cell class （2021.01.30）	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.71e-07	194	104	7	8388fe4df3461d85b21bd6847a4d32c030aaece4
ToppCell	BAL-Control-Lymphocyte-B\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.71e-07	194	104	7	1537e2285d0a8d0a4175dd0b8b1d1ccd887229fc
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_plasma\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 IGHV3-48 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-74	3.84e-07	195	104	7	0b0615553b9a1b60d666d074ce4260919e2d5642
ToppCell	5'-Adult-LargeIntestine\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-7 PYGB IGHV3-74	3.84e-07	195	104	7	600174e35574fe7c44dd923adcf43686e7b01e39
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	3.84e-07	195	104	7	13f4ee21568fd747608412d33559d10561dbb3c8
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	3.98e-07	196	104	7	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	3.98e-07	196	104	7	c2e17f3b2217f20bd7f28a1db4aa7d9a95c52a9c
ToppCell	Lung_Parenchyma-Severe-Lymphocyte-B-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	4.11e-07	197	104	7	365654a344bfdd2533cfcbed05063427b40f47b9
ToppCell	Lung_Parenchyma-Severe-Lymphocyte-B-Plasmablast-Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	4.11e-07	197	104	7	9936dc179aa0cf8aadf77946b26c09ad33848dc2
ToppCell	Lung_Parenchyma-Severe-Lymphocyte-B\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	4.11e-07	197	104	7	9e0850b6bb952757c74ba816e30006199e562bfa
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	4.11e-07	197	104	7	0e56255862fed099e771ebd2529393dc5a3641ba
ToppCell	Parenchyma_COVID-19-Immune-TX-Plasma_cells\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	4.11e-07	197	104	7	3259d7ce3e6dde1beda8b534bdf7ff5c7fc1a46c
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 IGHV3-74	4.11e-07	197	104	7	da175e66d0a743a1b91d46f224b5ff1d37aa5410
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	4.11e-07	197	104	7	fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	4.11e-07	197	104	7	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	Lung_Parenchyma-Severe-Lymphocyte-B-Plasmablast-Plasmablast-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 IGHV3-33 IKZF3 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	4.11e-07	197	104	7	5474774c2ff7a13ec1a020e2fef4efa72e34727b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GIMAP4 ENPP2 SPTBN1 DGKH DST MCTP1 PLCB4	4.56e-07	200	104	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GIMAP4 ENPP2 SPTBN1 SERPINB6 DST MCTP1 PLCB4	4.56e-07	200	104	7	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GIMAP4 ENPP2 SPTBN1 SERPINB6 DST MCTP1 PLCB4	4.56e-07	200	104	7	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	tumor_Lung-B_lymphocytes-Plasma_cells\|tumor_Lung / Location, Cell class and cell subclass	IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7 CNGB3	2.88e-06	169	104	6	b36b7632ce55fc7b6b8b66020563d360b3de6fd7
ToppCell	Control-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	2.98e-06	170	104	6	fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCell	Control-Lymphoid-B_Plasma\|Control / Disease state, Lineage and Cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-11 IGHV3-7	3.18e-06	172	104	6	61e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell	COPD-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.52e-06	175	104	6	d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7 SPTBN1	3.63e-06	176	104	6	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	droplet-Marrow-nan-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GIMAP4 MKRN1 SLC25A37 SLC6A9 SH3GLB1 KEL	3.63e-06	176	104	6	f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGHV3-48 IGHV3-33 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-7	3.75e-06	177	104	6	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	3.75e-06	177	104	6	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 IGHV3-33 IKZF3 SGTB IGHV3-7 ARSK	3.75e-06	177	104	6	b326376e879afef579b1b7094d756aaff0de270b
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 IGHV3-33 IKZF3 SGTB IGHV3-7 ARSK	3.75e-06	177	104	6	393882f1bf7658a17e10a771b803339f16fb2e69
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	IGHV3-48 IGHV3-30 IGHV3-23 IGHV3-21 IGHV3-11 IGHV3-7	3.75e-06	177	104	6	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
Disease	tumor necrosis factor ligand superfamily member 11 measurement	CFH IGHV3-21 IGHV3-11 IGHV3-7	7.99e-08	13	98	4	EFO_0010617
Disease	acylphosphatase-2 measurement	CFH NLRP12 SPTBN1	1.42e-07	4	98	3	EFO_0801344
Disease	tyrosine-protein kinase BTK measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020819
Disease	eukaryotic translation initiation factor 1A, X-chromosomal measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801589
Disease	docking protein 2 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801543
Disease	sumo-conjugating enzyme UBC9 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020757
Disease	regulatory factor X-associated protein measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801999
Disease	transforming growth factor beta-3 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020782
Disease	troponin i, cardiac muscle measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020788
Disease	eukaryotic initiation factor 4a-III measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020366
Disease	probable RNA-binding protein 23 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801917
Disease	polyUbiquitin K48-linked measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0022007
Disease	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C measurement	CFH MGAT4C	1.09e-05	2	98	2	EFO_0802264
Disease	vacuolar protein sorting-associated protein 4B measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0802209
Disease	beta-defensin 128 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801420
Disease	bromodomain-containing protein 1 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801431
Disease	poly(rC)-binding protein 1 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801894
Disease	protein kinase c beta type (splice variant beta-II) measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020678
Disease	ubiquitin-conjugating enzyme E2 D4 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0802181
Disease	thymocyte nuclear protein 1 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0802132
Disease	selenide, water dikinase 1 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0802045
Disease	ubiquitin-conjugating enzyme E2 N measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020841
Disease	immunoglobulin superfamily DCC subclass member 3 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0801689
Disease	tyrosine-protein kinase CSK measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020820
Disease	high mobility group protein B1 measurement	CFH NLRP12	1.09e-05	2	98	2	EFO_0020449
Disease	Thyroid carcinoma	ENPP2 TSC2 MSH6 PIK3CA	1.40e-05	44	98	4	C0549473
Disease	Adenocarcinoma of large intestine	MSH6 ZNRF3 PIK3CA PRKDC TAF1	1.75e-05	96	98	5	C1319315
Disease	DNA/RNA-binding protein KIN17 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801536
Disease	dynein light chain 1, cytoplasmic measurement	CFH IGHV3-7	3.27e-05	3	98	2	EFO_0020339
Disease	eukaryotic translation initiation factor 5A-1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020370
Disease	ephrin type-a receptor 5 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020353
Disease	small ubiquitin-related modifier 3 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0022025
Disease	2'-5'-oligoadenylate synthase 1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0021911
Disease	prefoldin subunit 5 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020652
Disease	B melanoma antigen 2 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801401
Disease	polyadenylate-binding protein 4 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801897
Disease	polycomb protein SCMH1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801898
Disease	neutrophil cytosol factor 2 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801837
Disease	nuclear RNA export factor 1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801855
Disease	n-terminal Xaa-Pro-Lys N-methyltransferase 1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801820
Disease	NAD kinase measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801821
Disease	cAMP-regulated phosphoprotein 19 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020223
Disease	toll-interacting protein measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802133
Disease	interleukin-16 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801717
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 4 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020124
Disease	sperm-associated antigen 11A measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802082
Disease	serine-rich single-pass membrane protein 1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802056
Disease	RNA-binding protein 3 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802031
Disease	rho GTPase-activating protein 25 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802011
Disease	retinoid-binding protein 7 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0802006
Disease	glucose-6-phosphate isomerase measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020407
Disease	high mobility group protein B2 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0801676
Disease	inhibitor of growth protein 1 measurement	CFH NLRP12	3.27e-05	3	98	2	EFO_0020471
Disease	probable ATP-dependent RNA helicase DDX58 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0801913
Disease	aldose reductase measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0801364
Disease	zinc finger protein 18 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0802226
Disease	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0801374
Disease	protein nov homolog measurement	CFH ENPP2	6.52e-05	4	98	2	EFO_0020685
Disease	uncharacterized protein KIAA0040 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0802196
Disease	urea transporter 2 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0802203
Disease	caspase-8 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0010764
Disease	integral membrane protein 2A measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0801704
Disease	CUB and Sushi domain-containing protein 2 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0803314
Disease	ubiquitin-fold modifier-conjugating enzyme 1 measurement	CFH NLRP12	6.52e-05	4	98	2	EFO_0020843
Disease	brain measurement, neuroimaging measurement	DPYSL2 SGTB ENPP2 SPTBN1 PKDCC ADAMTS8 MCTP1 CADPS PYGB	9.20e-05	550	98	9	EFO_0004346, EFO_0004464
Disease	serine/threonine-protein kinase 17B measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0008281
Disease	chymotrypsin-like protease CTRL-1 measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0801476
Disease	protein fam107a measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0020673
Disease	n-acetyltransferase 14 measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0801819
Disease	lysophosphatidylcholine acyltransferase 2 measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0801775
Disease	low-density lipoprotein receptor-related protein 1B measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0021873
Disease	SH3 domain-binding protein 2 measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0802063
Disease	high mobility group protein B3 measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0801677
Disease	general transcription factor II-I measurement	CFH NLRP12	1.08e-04	5	98	2	EFO_0801623
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	NLRP12 TSC2 BRD3 LRP1B PIK3CA	1.38e-04	148	98	5	C0279702
Disease	galectin-2 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0020397
Disease	Ena/VASP-like protein measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801564
Disease	endothelial differentiation-related factor 1 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801571
Disease	cytochrome c oxidase subunit 6C measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801515
Disease	protein NDRG4 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801954
Disease	cyclin-dependent kinase 8:cyclin-c complex measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0020297
Disease	voltage-dependent calcium channel subunit alpha-2/delta-3 measurement	CFH CACNA2D3	1.62e-04	6	98	2	EFO_0802218
Disease	nischarin measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801841
Disease	NTF2-related export protein 1 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801847
Disease	acyl-CoA-binding domain-containing protein 6 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801342
Disease	riboflavin kinase measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0802016
Disease	GDP-fucose protein O-fucosyltransferase 1 measurement	CFH NLRP12	1.62e-04	6	98	2	EFO_0801621
Disease	keratinocyte differentiation-associated protein measurement	CFH NLRP12	2.27e-04	7	98	2	EFO_0801743
Disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 measurement	CFH NLRP12	2.27e-04	7	98	2	EFO_0020108
Disease	osteocalcin measurement	CFH NLRP12	2.27e-04	7	98	2	EFO_0010232
Disease	glutathione s-transferase p measurement	CFH NLRP12	2.27e-04	7	98	2	EFO_0020410
Disease	pyridoxal kinase measurement	CFH NLRP12	3.02e-04	8	98	2	EFO_0021919
Disease	switch-associated protein 70 measurement	CFH NLRP12	3.02e-04	8	98	2	EFO_0802107
Disease	Adenoid Cystic Carcinoma	PIK3CA PYGB PRKDC BRD1	3.51e-04	100	98	4	C0010606
Disease	HEPATOCELLULAR CARCINOMA	IGF2R PIK3CA	3.87e-04	9	98	2	114550
Disease	beta-mannosidase measurement	CFH NLRP12	3.87e-04	9	98	2	EFO_0801421
Disease	Adult Hepatocellular Carcinoma	TSC2 PIK3CA	3.87e-04	9	98	2	C0279607
Disease	Hepatocellular carcinoma	IGF2R PIK3CA	3.87e-04	9	98	2	cv:C2239176
Disease	leucine-rich repeat serine/threonine-protein kinase 2 measurement	CFH NLRP12	3.87e-04	9	98	2	EFO_0021876
Disease	tumor necrosis factor ligand superfamily member 14 measurement	CFH NLRP12	3.87e-04	9	98	2	EFO_0010613

Protein segments in the cluster

Peptide	Gene	Start	Entry
MYAFVRFLEDNVCYA	BEND5	1	Q7L4P6
EIKNIRAFYYAMCAE	ARSK	271	Q6UWY0
KDNYFMTQNERYKAA	ACOX2	66	Q99424
VQEYCYDNIHFMKAF	BZW2	346	Q9Y6E2
DNCMKYNARDTVFYR	BRD1	636	O95696
FAADVRLMFSNCYKY	BRD3	376	Q15059
YCSQKSLNEASMDEY	ALG13	211	Q9NP73
QEYCYDNIHFMKAFQ	BZW1	346	Q7L1Q6
EDFNTMFSNCYLYNK	BRDT	96	Q58F21
QCEKYNAYNYTDMDG	ADAMTS8	591	Q9UP79
DCQRHESYKTQYRAM	EAPP	191	Q56P03
ERFQYKCNMGYEYSE	CFH	231	P08603
ARDCKFTGNFFYNYM	DHCR7	206	Q9UBM7
FNSAVMHLDYYCNKN	RBM46	391	Q8TBY0
FACTYKDDYMISKDN	PARPBP	431	Q9NWS1
IYFADMSSKSANYCF	PARP2	461	Q9UGN5
YFANLSNKSQRYMAD	KCNJ4	31	P48050
QYTFAMCSYREKKAE	CADPS	551	Q9ULU8
NFCANTSDYYVMLED	MGAT4C	211	Q9UBM8
FMARNYEFLAYEASK	DAOA	106	P59103
VVMENFRKYQHFSCY	KCNMB2	161	Q9Y691
YFRAMFCNDLKEKYE	KLHL6	96	Q8WZ60
QMNSLRAEDTAVYYC	IGHV3-11	101	P01762
QMNSLRAEDTAVYYC	IGHV3-30-5	101	P0DP03
YKEFCDFYAKFNMAN	LIMS3	51	P0CW19
YKEFCDFYAKFNMAN	LIMS4	51	P0CW20
VYAKLYMDGQNCRNS	LRP1B	4561	Q9NZR2
MVLVNAAYYVNSCFD	MCTP1	786	Q6DN14
DYFRDKTQYIFNNMV	MAN2A1	186	Q16706
VYMAFKDRFQLTDCQ	DPYSL2	166	Q16555
QMNSLRAEDTAVYYC	IGHV3-7	101	P01780
QMNSLRAEDTAVYYC	IGHV3-30-3	101	P0DP02
SKMDECQKYAEQYSA	DST	1346	Q03001
ADVHNAMDNYECNLY	FEM1B	431	Q9UK73
ESVYGQCKAIFYMNN	FETUB	111	Q9UGM5
QMNSLRAEDTAVYYC	IGHV3-48	101	P01763
EDKVISYNACAAQMY	OR5B3	86	Q8NH48
MDTKRCFANRFDDYQ	LANCL3	1	Q6ZV70
TQKLFECDRDQMYYN	LRPPRC	946	P42704
QMNSLRAEDTAVYYC	IGHV3-74	101	A0A0B4J1X5
SVDGYSEKCVMNNYF	DGKH	761	Q86XP1
DCMRRLFYNFDKNYK	MSH6	1031	P52701
QMNSLRAEDTAVYYC	IGHV3-21	101	A0A0B4J1V1
EFERFQEMCYKAYLA	PIK3CA	976	P42336
AMVQTEDEYQFCYQA	PTPRS	1921	Q13332
YYFANASEPERCQKM	PANK3	161	Q9H999
DYLYCEMCQNFFIDS	PRDM9	201	Q9NQV7
SLAERHYYNCDFKMC	CDC16	236	Q13042
CIDRFRAATNVQMYY	GPR37	356	O15354
YDYQAMCRANKESSD	CACNA2D3	901	Q8IZS8
FKSMEVANFYYEADC	CEBPB	21	P17676
KRLDCQSAMFNDYNF	AMD1	306	P17707
MQKATYYDNAAAALF	HOXB3	1	P14651
RFPCKAMFEEAYSNY	COQ8A	626	Q8NI60
AMFEEAYSNYCKRQA	COQ8A	631	Q8NI60
QMNSLRAEDTAVYYC	IGHV3-23	101	P01764
QMNSLRAEDTAVYYC	IGHV3-30	101	P01768
LNKYRNKYCMFNDDI	ME3	291	Q16798
DEDFTNMSQFCNYIY	LAS2	76	Q8IYD9
YYNCSAMVSKAARQE	CUL9	2276	Q8IWT3
VYVFNCSEQMDYKSC	DNAH9	1891	Q9NYC9
FYAENFMANTYLRKD	CCDC168	2526	Q8NDH2
CFDVNYNSSYMYEKE	IKZF3	281	Q9UKT9
FSYNSNCQEKMSDYI	CYP4F22	216	Q6NT55
NCLAYKNDKQMSYGF	ENPP2	666	Q13822
VCTDFADNMDFYYTK	CNST	696	Q6PJW8
QMNSLRAEDTAVYYC	IGHV3-33	101	P01772
YKEAMSNKACRYFDE	MKRN1	361	Q9UHC7
YASACQMKYEKDQGS	IGF2R	826	P11717
LSFENHCSKYQQYKM	PLCB4	406	Q15147
CEGMNEKRNLYNAYR	PKDCC	331	Q504Y2
NKEGCYTNRMYQRAE	GIMAP4	216	Q9NUV9
CAYYSMIAAEQRLKD	TAF1	886	P21675
CVNDDLVAKNYACYM	TDRD12	196	Q587J7
MDENYFVNYTFKDRS	KBTBD4	11	Q9NVX7
CFYYNQFIRDRFSMD	PKDREJ	1736	Q9NTG1
YFACYENMKRTLNDV	SLC25A37	121	Q9NYZ2
DYLYCEMCQNFFIDS	PRDM7	201	Q9NQW5
FRDSCQKFYQAEMEE	SERPINB6	106	P35237
CLNDFVEAQMTYYAQ	SH3GLB1	226	Q9Y371
NYYQCHFCDKAFMNQ	DZIP1	196	Q86YF9
YCVINNQEMGFYKDA	SPTBN1	2226	Q01082
NSYFMVEVKCRDQDF	CNDP1	246	Q96KN2
NQNYFRACMDDTIAY	CNGB3	451	Q9NQW8
RACMDDTIAYMNNYS	CNGB3	456	Q9NQW8
YELCMFFRNYKEAEA	SPG11	1556	Q96JI7
AISMDKNSYTAFYNR	TTC6	131	Q86TZ1
YKEAMSNKACRYFAE	MKRN3	391	Q13064
MSEYNATQSDYRERC	STX1A	131	Q16623
SCNMMAFLADEYCNY	RFX8	171	Q6ZV50
FLYVARNAKDCMVSY	SULT1C2	126	O00338
RNAKDCMVSYYHFQR	SULT1C2	131	O00338
RFKVFADYEAYMQCQ	PYGB	771	P11216
NASAYCLMYINDKAQ	USP25	646	Q9UHP3
TMASYNKFHNNCYRD	SLC6A9	381	P48067
NEDFRRYQMESFSKY	SCLT1	16	Q96NL6
CNERFQYKYQLRSHM	ZBTB47	581	Q9UFB7
NMSFVRYKEVYAAAA	PRKDC	2306	P78527
IDFRYSQFYMEDSFC	ZCCHC4	226	Q9H5U6
FSKAACFSQYETMYQ	ZNRF3	456	Q9ULT6
MKEENYAAAVDCYTQ	SGTB	96	Q96EQ0
QRSEDFDIYTLYCMN	PLEKHG2	181	Q9H7P9
EYCNYAMDSSVENMY	ZCWPW2	11	Q504Y3
MSKYYNDCYAVLRDA	PICK1	341	Q9NRD5
FSFVKNSMKYYDDCA	PPIP5K1	336	Q6PFW1
SCDEDGYYRKMQCDQ	SPOCK2	336	Q92563
FNSCYLDEYIARMVQ	TSC2	186	P49815
KMYACQYCDAVFAQS	ZBTB40	891	Q9NUA8
EKAFQFYNSCMDTLA	KEL	146	P23276
YLFYINCREMNQSAT	NLRP12	246	P59046