Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiongalactosidase activity

GLB1L3 GLB1L2 GLA

4.46e-0671023GO:0015925
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A7 SLC13A3 SLC6A9 SLC13A1 SLC29A1

5.93e-05811025GO:0015370
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

GLB1L3 GLB1L2 GLA GUSB AGL SMPD1

9.66e-051441026GO:0016798
GeneOntologyMolecularFunctionthiolester hydrolase activity

ACOT1 ACOT6 ACOT4 CPT1C

9.67e-05471024GO:0016790
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP6V0B SLC5A7 SLC13A3 NDUFA9 SLC18B1 SLC6A9 SLC13A1 SLC29A1

1.56e-043011028GO:0022853
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

GLB1L3 GLB1L2 GLA GUSB AGL

1.86e-041031025GO:0004553
GeneOntologyMolecularFunctioncarbohydrate binding

MAG CLEC18B CLEC18C CLEC3A GUSB CD33 AGL NCAN

1.91e-043101028GO:0030246
GeneOntologyMolecularFunctionbeta-galactosidase activity

GLB1L3 GLB1L2

2.56e-0451022GO:0004565
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

ACOT1 ACOT6 ACOT4

3.46e-04271023GO:0047617
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A7 SLC13A3 SLC6A9 SLC13A1 SLC29A1

3.63e-041191025GO:0015294
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ACOT1 ACOT6 ACOT4

3.86e-04281023GO:0016289
GeneOntologyMolecularFunctionpolysaccharide binding

CLEC18B CLEC18C AGL

5.24e-04311023GO:0030247
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP6V0B SLC5A7 SLC13A3 NDUFA9 SLC18B1 ABCA7 SLC6A9 SLC13A1 SLC29A1

7.55e-044771029GO:0022804
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC5A7 AQP8 SLC6A9 SLC7A10

8.66e-04831024GO:0015101
GeneOntologyMolecularFunctionsymporter activity

SLC5A7 SLC13A3 SLC6A9 SLC13A1 SLC29A1

1.04e-031501025GO:0015293
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP6V0B SLC5A7 SLC13A3 AQP8 STING1 NDUFA9 SLC18B1 SLC6A9 SLC13A1 SLC29A1

1.38e-0362710210GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP6V0B SLC5A7 SLC13A3 AQP8 STING1 NDUFA9 SLC18B1 AQP6 SLC6A9 SLC13A1 SLC29A1

1.69e-0375810211GO:0015318
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A7 SLC13A3 SLC6A9 SLC13A1 SLC29A1

1.85e-031711025GO:0015081
GeneOntologyBiologicalProcessregulation of synaptic transmission, glycinergic

SLC6A9 SLC7A10

2.52e-0521042GO:0060092
GeneOntologyBiologicalProcesssaturated monocarboxylic acid metabolic process

ACOT1 ACOT4

2.52e-0521042GO:0032788
GeneOntologyBiologicalProcessunsaturated monocarboxylic acid metabolic process

ACOT1 ACOT4

2.52e-0521042GO:0032789
GeneOntologyBiologicalProcessquinone biosynthetic process

NDUFA9 COQ2 COQ7

8.04e-05171043GO:1901663
GeneOntologyBiologicalProcessubiquinone biosynthetic process

NDUFA9 COQ2 COQ7

8.04e-05171043GO:0006744
GeneOntologyBiologicalProcessorganic cation transport

SLC5A7 AQP8 SLC18B1 ADORA2A SLC6A9 SLC7A10

9.38e-051451046GO:0015695
GeneOntologyBiologicalProcessubiquinone metabolic process

NDUFA9 COQ2 COQ7

1.33e-04201043GO:0006743
GeneOntologyBiologicalProcessneurotransmitter uptake

SLC18B1 SLC6A9 NOS1 SLC29A1

1.37e-04521044GO:0001504
GeneOntologyCellularComponentlysosomal lumen

APOB GLA GUSB NCAN SMPD1

1.36e-04981055GO:0043202
GeneOntologyCellularComponentmicrobody

AMACR ACOT1 ACOT6 STING1 ACOT4 CD33

1.69e-041621056GO:0042579
GeneOntologyCellularComponentperoxisome

AMACR ACOT1 ACOT6 STING1 ACOT4 CD33

1.69e-041621056GO:0005777
GeneOntologyCellularComponentsecretory vesicle

ANPEP FSTL4 SLC5A7 STING1 HUWE1 SLC18B1 PHAF1 SLC6A9 SERPINA1 GLA GUSB CD33 AGL SMPD1 PCSK4 NOS1

4.75e-04124610516GO:0099503
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA3

5.16e-0471052GO:0097486
GeneOntologyCellularComponentsecretory granule

ANPEP FSTL4 STING1 HUWE1 SLC18B1 SLC6A9 SERPINA1 GLA GUSB CD33 AGL SMPD1 PCSK4 NOS1

5.46e-04101410514GO:0030141
GeneOntologyCellularComponentendosome lumen

PGA4 APOB PGA3

1.31e-03431053GO:0031904
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA3

1.33e-03111052GO:0031906
DomainBAAT_C

ACOT1 ACOT6 ACOT4

1.57e-0651023IPR014940
DomainBAAT_C

ACOT1 ACOT6 ACOT4

1.57e-0651023PF08840
Domain-

GLB1L3 GLB1L2 GUSB PCSK7 CPXM1 PCSK4

2.90e-067310262.60.120.260
DomainGlycoside_hydrolase_SF

GLB1L3 GLB1L2 GLA GUSB AGL

1.03e-05531025IPR017853
DomainGalactose-bd-like

GLB1L3 GLB1L2 GUSB PCSK7 CPXM1 PCSK4

1.26e-05941026IPR008979
Domain-

GLB1L3 GLB1L2 GUSB AGL

3.85e-053510243.20.20.80
DomainGlyco_hydro_catalytic_dom

GLB1L3 GLB1L2 GUSB AGL

5.37e-05381024IPR013781
DomainC-type_lectin_CS

CLEC18B CLEC18C CLEC3A NCAN

8.78e-05431024IPR018378
DomainGlyco_hydro_35

GLB1L3 GLB1L2

1.76e-0441022PF01301
DomainGly_Hdrlase_35_cat

GLB1L3 GLB1L2

1.76e-0441022IPR031330
DomainGlycoside_Hdrlase_35

GLB1L3 GLB1L2

1.76e-0441022IPR001944
DomainBile_Hydr_Trans

ACOT1 ACOT4

1.76e-0441022PF04775
DomainB-gal_1-like

GLB1L3 GLB1L2

1.76e-0441022IPR026283
DomainGLYCOSYL_HYDROL_F35

GLB1L3 GLB1L2

1.76e-0441022PS01182
DomainThio_Ohase/aa_AcTrfase

ACOT1 ACOT4

1.76e-0441022IPR006862
DomainAcyl-CoA_thioEstase_long-chain

ACOT1 ACOT4

1.76e-0441022IPR016662
DomainNa/sul_symport

SLC13A3 SLC13A1

2.92e-0451022IPR001898
DomainNa_sulph_symp

SLC13A3 SLC13A1

2.92e-0451022PF00939
DomainPrprotnconvertsP

PCSK7 PCSK4

6.09e-0471022IPR002884
DomainAspartic_peptidase_N

PGA4 PGA3

6.09e-0471022IPR012848
DomainP_proprotein

PCSK7 PCSK4

6.09e-0471022PF01483
DomainS8_pro-domain

PCSK7 PCSK4

6.09e-0471022IPR032815
Domain-

PCSK7 PCSK4

6.09e-04710223.30.70.850
DomainS8_pro-domain

PCSK7 PCSK4

6.09e-0471022PF16470
DomainA1_Propeptide

PGA4 PGA3

6.09e-0471022PF07966
DomainC_TYPE_LECTIN_1

CLEC18B CLEC18C CLEC3A NCAN

9.65e-04801024PS00615
DomainPeptidase_S8_His-AS

PCSK7 PCSK4

1.04e-0391022IPR022398
DomainPeptidase_S8_Ser-AS

PCSK7 PCSK4

1.04e-0391022IPR023828
DomainLectin_C

CLEC18B CLEC18C CLEC3A NCAN

1.16e-03841024PF00059
DomainCLECT

CLEC18B CLEC18C CLEC3A NCAN

1.16e-03841024SM00034
DomainC_TYPE_LECTIN_2

CLEC18B CLEC18C CLEC3A NCAN

1.21e-03851024PS50041
DomainC-type_lectin-like

CLEC18B CLEC18C CLEC3A NCAN

1.26e-03861024IPR001304
DomainAspartic_peptidase_A1

PGA4 PGA3

1.29e-03101022IPR001461
DomainPeptidase_S8_subtilisin-rel

PCSK7 PCSK4

1.29e-03101022IPR015500
DomainPEPTIDASE_A1

PGA4 PGA3

1.29e-03101022IPR033121
DomainMIP_CS

AQP8 AQP6

1.29e-03101022IPR022357
DomainAsp

PGA4 PGA3

1.29e-03101022PF00026
DomainPEPTIDASE_A1

PGA4 PGA3

1.29e-03101022PS51767
DomainSUBTILASE_ASP

PCSK7 PCSK4

1.29e-03101022PS00136
DomainSUBTILASE_HIS

PCSK7 PCSK4

1.29e-03101022PS00137
DomainSUBTILASE_SER

PCSK7 PCSK4

1.29e-03101022PS00138
Domain-

PCSK7 PCSK4

1.57e-031110223.40.50.200
DomainPeptidase_S8/S53_dom

PCSK7 PCSK4

1.57e-03111022IPR000209
DomainPeptidase_S8

PCSK7 PCSK4

1.57e-03111022PF00082
Domain-

PGA4 PGA3

1.88e-031210222.40.70.10
DomainASP_PROTEASE

PGA4 PGA3

1.88e-03121022PS00141
Domain-

CLEC18B CLEC18C CLEC3A NCAN

1.97e-039710243.10.100.10
DomainC-type_lectin-like/link

CLEC18B CLEC18C CLEC3A NCAN

2.12e-03991024IPR016186
DomainAspartic_peptidase_AS

PGA4 PGA3

2.22e-03131022IPR001969
Domain-

TNFSF14 CBLN1 MMRN2

2.57e-035010232.60.120.40
DomainMIP

AQP8 AQP6

2.57e-03141022PS00221
DomainMIP

AQP8 AQP6

2.57e-03141022PF00230
DomainCTDL_fold

CLEC18B CLEC18C CLEC3A NCAN

2.81e-031071024IPR016187
DomainMIP

AQP8 AQP6

2.96e-03151022IPR000425
Domain-

AQP8 AQP6

2.96e-031510221.20.1080.10
Domain-

CLEC18B CLEC18C

2.96e-031510223.40.33.10
DomainCAP

CLEC18B CLEC18C

2.96e-03151022PF00188
DomainCAP_domain

CLEC18B CLEC18C

2.96e-03151022IPR014044
DomainSCP

CLEC18B CLEC18C

2.96e-03151022SM00198
DomainAllrgn_V5/Tpx1

CLEC18B CLEC18C

2.96e-03151022IPR001283
DomainAquaporin-like

AQP8 AQP6

2.96e-03151022IPR023271
DomainPropept_inh

PCSK7 PCSK4

3.81e-03171022IPR009020
DomainPeptidase_aspartic_dom

PGA4 PGA3

3.81e-03171022IPR021109
Domainig

MAG FSTL4 TYRO3 HMCN1 CD33

3.88e-031901025PF00047
DomainImmunoglobulin

MAG FSTL4 TYRO3 HMCN1 CD33

3.88e-031901025IPR013151
DomainTumour_necrosis_fac-like_dom

TNFSF14 CBLN1 MMRN2

3.92e-03581023IPR008983
DomainFurin_repeat

CRELD1 PCSK4

4.27e-03181022IPR006212
DomainFU

CRELD1 PCSK4

4.27e-03181022SM00261
PathwayWP_7OXOC_AND_7BETAHC_PATHWAYS

AMACR ACOT1 ACOT6 ACOT4

1.61e-0527814M40054
PathwayREACTOME_GLYCOSPHINGOLIPID_CATABOLISM

GLB1L3 GLB1L2 GLA SMPD1

4.11e-0534814MM17076
PathwayREACTOME_METABOLISM_OF_LIPIDS

GLB1L3 AMACR FA2H ACOT1 ACOT6 GLB1L2 LBR ACOT4 PTGIS LHB GLA SMPD1 PIK3R5

4.85e-056208113MM15193
PathwayREACTOME_GLYCOSPHINGOLIPID_CATABOLISM

GLB1L3 GLB1L2 GLA SMPD1

7.14e-0539814M48042
PathwayREACTOME_SPHINGOLIPID_METABOLISM

GLB1L3 FA2H GLB1L2 GLA SMPD1

1.84e-0492815MM15086
PathwayWP_OXYSTEROLS_DERIVED_FROM_CHOLESTEROL

AMACR ACOT1 ACOT6 ACOT4

2.06e-0451814M39754
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

GLB1L3 GLB1L2 GLA SMPD1

2.39e-0453814MM14647
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0B SLC5A7 SLC13A3 APOB AQP8 AQP6 ABCA7 SLC6A9 SLC13A1 SCARB1 DERL3 SLC7A10 SLC29A1

2.69e-047368113M27287
PathwayREACTOME_HS_GAG_DEGRADATION

GLB1L3 GLB1L2 GUSB

2.98e-0423813MM14804
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

GLB1L3 GLB1L2 GUSB NCAN

3.17e-0457814M692
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A3 SLC13A1

3.22e-045812MM15099
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A3 SLC13A1

3.22e-045812M27354
PathwayREACTOME_GLYCOSPHINGOLIPID_METABOLISM

GLB1L3 GLB1L2 GLA SMPD1

3.39e-0458814M576
PathwayREACTOME_HS_GAG_DEGRADATION

GLB1L3 GLB1L2 GUSB

3.39e-0424813M636
PathwayREACTOME_METABOLISM_OF_LIPIDS

GLB1L3 AMACR FA2H ACOT1 ACOT6 GLB1L2 LBR ACOT4 PTGIS LHB GLA SMPD1 PIK3R5

3.53e-047578113M27451
PathwayREACTOME_SPHINGOLIPID_METABOLISM

GLB1L3 FA2H GLB1L2 GLA SMPD1

3.72e-04107815M14857
PathwayREACTOME_SCAVENGING_BY_CLASS_B_RECEPTORS

APOB SCARB1

4.82e-046812M27220
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0B SLC5A7 SLC13A3 APOB AQP8 ABCA7 SLC6A9 SLC13A1 SCARB1 DERL3 SLC7A10 SLC29A1

4.85e-046818112MM14985
PathwayREACTOME_PEROXISOMAL_LIPID_METABOLISM

AMACR ACOT6 ACOT4

5.40e-0428813MM15010
PathwayREACTOME_PEROXISOMAL_LIPID_METABOLISM

AMACR ACOT6 ACOT4

6.00e-0429813M2286
PathwayREACTOME_SURFACTANT_METABOLISM

PGA4 ADORA2A PGA3

6.63e-0430813M27566
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

GLB1L3 GLB1L2 GUSB NCAN HAS1

7.85e-04126815M695
PathwayWP_MONOAMINE_TRANSPORT

SLC5A7 ADORA2A NOS1

8.04e-0432813M39724
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A7 SLC13A3 SLC6A9 SLC13A1

9.48e-0476814MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC5A7 SLC13A3 SLC6A9 SLC13A1

1.38e-0384814M27334
Pubmed

Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

ACOT1 ACOT6 ACOT4

2.74e-075106316940157
Pubmed

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

ACOT1 ACOT6 ACOT4

2.28e-069106316103133
Pubmed

Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.

ACOT1 APOB SERPINA1 GUSB ADIPOR2

3.72e-067610658288233
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

PGA4 ANPEP GPRC5C APOB CPN2 CUTA SERPINA1 GLA HMCN1 GUSB ENTPD2 MMRN2 SMPD1 PGA3

4.77e-0610701061423533145
Pubmed

A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.

ACOT1 APOB SERPINA1

5.93e-061210638631881
Pubmed

Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.

PGA4 EDN3 SCARB1 PGA3

7.57e-0641106423676500
Pubmed

Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification.

NDUFA9 SCARB1 ADIPOR2

7.70e-0613106318245842
Pubmed

Inhibition of the equilibrative nucleoside transporter 1 and activation of A2A adenosine receptors by 8-(4-chlorophenylthio)-modified cAMP analogs and their hydrolytic products.

ADORA2A SLC29A1

9.20e-062106219801629
Pubmed

Expression of myeloid antigen in neoplastic plasma cells is related to adverse prognosis in patients with multiple myeloma.

ANPEP CD33

9.20e-062106224991573
Pubmed

[The Relationship between the Expressions of CD33 and CD13 and the Prognosis of Patients with Multiple Myeloma].

ANPEP CD33

9.20e-062106235123618
Pubmed

Oocyte-Specific Deletion of Slc6a9 Encoding the GLYT1 Glycine Transporter Eliminates Glycine Transport in Mouse Preimplantation Embryos and Their Ability to Counter Hypertonic Stress.

AMHR2 SLC6A9

9.20e-062106237887344
Pubmed

Adenosine A2A receptor antagonism increases nNOS-immunoreactive neurons in the striatum of Huntington transgenic mice.

ADORA2A NOS1

9.20e-062106218586241
Pubmed

HIV-1 proprotein processing as a target for gene therapy.

SERPINA2 SERPINA1

9.20e-062106212621451
Pubmed

The expression of myeloid antigens CD13 and/or CD33 is a marker of ALK+ anaplastic large cell lymphomas.

ANPEP CD33

9.20e-062106218794057
Pubmed

Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.

SERPINA1 DERL3

9.20e-062106216449193
Pubmed

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant.

SERPINA2 SERPINA1

9.20e-06210628227051
Pubmed

Mechanisms of alpha1-antitrypsin inhibition of cellular serine proteases and HIV-1 protease that are essential for HIV-1 morphogenesis.

SERPINA2 SERPINA1

9.20e-062106212878320
Pubmed

Expression of AQP6 and AQP8 in epithelial ovarian tumor.

AQP8 AQP6

9.20e-062106226779650
Pubmed

PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.

APOB PCSK7

9.20e-062106237967646
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

ANPEP APOB CPN2 SERPINA1 GUSB MMRN2 PLXNB1

1.45e-05257106716335952
Pubmed

Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3.

ACOT1 APOB SERPINA1

1.50e-051610638798769
Pubmed

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.

CPN2 PTGIS NOS1

2.57e-0519106321052031
Pubmed

Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.

CLEC18B CLEC18C

2.76e-053106226170455
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA3

2.76e-05310627926498
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA3

2.76e-05310629561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA3

2.76e-053106221455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA3

2.76e-053106219800305
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA3

2.76e-053106224170207
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA3

2.76e-05310623014868
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA3

2.76e-05310622799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA3

2.76e-053106219872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA3

2.76e-05310621968039
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA3

2.76e-05310628053437
Pubmed

Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.

ADORA2A SLC29A1

2.76e-053106235790189
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA3

2.76e-05310622566575
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA3

2.76e-05310622229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA3

2.76e-053106225314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA3

2.76e-053106219890696
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA3

2.76e-05310628244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA3

2.76e-053106221407214
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA3

2.76e-05310626774973
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA3

2.76e-05310626300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA3

2.76e-053106222304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA3

2.76e-053106224004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA3

2.76e-05310628038355
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA3

2.76e-05310622227273
Pubmed

Induced pluripotent stem cells derived from mouse models of lysosomal storage disorders.

GLA GUSB

2.76e-053106220385825
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA3

2.76e-053106223034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA3

2.76e-053106224125879
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA3

2.76e-05310628751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA3

2.76e-05310623554488
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA3

2.76e-053106223521833
Pubmed

Clinical spectrum in multiple families with primary COQ10 deficiency.

COQ2 COQ7

2.76e-053106233215859
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA3

2.76e-05310623017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA3

2.76e-053106221989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA3

2.76e-05310629855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA3

2.76e-05310629797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA3

2.76e-05310622478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA3

2.76e-05310623815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA3

2.76e-053106210675278
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA3

2.76e-05310623780036
Pubmed

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

ACOT1 ACOT4

2.76e-053106210567408
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA3

2.76e-05310622901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA3

2.76e-05310623839486
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA3

2.76e-05310623467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA3

2.76e-05310624586732
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA3

2.76e-05310622892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA3

2.76e-053106224383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA3

2.76e-05310621455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA3

2.76e-05310622831884
Pubmed

Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice.

APOB SCARB1

2.76e-053106212235173
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA3

2.76e-05310622032552
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA3

2.76e-05310621812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA3

2.76e-05310627923573
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA3

2.76e-05310629061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA3

2.76e-053106212588289
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA3

2.76e-053106223897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA3

2.76e-053106211566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA3

2.76e-05310621956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA3

2.76e-05310628540382
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA3

2.76e-053106222992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA3

2.76e-053106220981206
Pubmed

The C-type lectin-like domain superfamily.

CLEC18B CLEC18C

2.76e-053106216336259
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA3

2.76e-05310628504820
Pubmed

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

CLEC18B CLEC18C

2.76e-053106233603190
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA3

2.76e-053106221970995
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA3

2.76e-053106220428942
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA3

2.76e-05310629525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA3

2.76e-05310627886402
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA3

2.76e-053106217379991
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA3

2.76e-053106221547904
Pubmed

Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.

ACOT1 APOB SERPINA1 GUSB ADIPOR2

3.59e-0512110658827514
Pubmed

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.

CLEC18B CLEC18C

5.50e-054106216709836
Pubmed

Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.

ACOT1 ACOT4

5.50e-054106215007068
Pubmed

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease.

ABCA7 CD33

5.50e-054106228477215
Pubmed

Diminished CD10, CD13, and CD15 expression in a differentiated granulocyte population in CML.

ANPEP CD33

5.50e-054106217662271
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA3

5.50e-054106223047493
Pubmed

SERPINA2 is a novel gene with a divergent function from SERPINA1.

SERPINA2 SERPINA1

5.50e-054106223826168
Pubmed

Molecular genetic analysis of familial hypercholesterolemia: spectrum and regional difference of LDL receptor gene mutations in Japanese population.

APOB SCARB1

5.50e-054106212417285
Pubmed

Prognostic value of immunophenotyping in elderly patients with acute myeloid leukemia: a single-institution experience.

ANPEP CD33

5.50e-054106218085638
InteractionTMEM100 interactions

GPR152 CLDN7 STING1 AQP6 CD33

7.46e-0735995int:TMEM100
InteractionBMP10 interactions

TNFSF14 GPR152 CLDN7 AQP6 CD33

1.34e-0562995int:BMP10
Cytoband16q23

FA2H CLEC3A

7.87e-056106216q23
Cytoband22q11.23

LHFPL7 ADORA2A DERL3

2.58e-0453106322q11.23
Cytoband14q24.3

ACOT1 ACOT6 ACOT4

1.33e-0393106314q24.3
Cytoband11q25

GLB1L3 GLB1L2

1.66e-0326106211q25
CytobandEnsembl 112 genes in cytogenetic band chr11q25

GLB1L3 GLB1L2

2.35e-03311062chr11q25
CytobandEnsembl 112 genes in cytogenetic band chr16q23

CLEC18B FA2H CLEC3A

2.51e-031161063chr16q23
Cytoband11q12.2

PGA4 PGA3

3.70e-0339106211q12.2
GeneFamilyAcyl-CoA thioesterases

ACOT1 ACOT6 ACOT4

5.99e-061068341
GeneFamilySolute carriers

SLC25A34 SLC5A7 SLC13A3 SLC18B1 SLC6A9 SLC13A1 SLC7A10 SLC29A1 SLC22A31

1.63e-05395689752
GeneFamilyProprotein convertase subtilisin/kexin family

PCSK7 PCSK4

4.93e-049682973
GeneFamilyC-type lectin domain family

CLEC18B CLEC18C CLEC3A

7.33e-0447683494
GeneFamilyAquaporins

AQP8 AQP6

1.23e-0314682305
GeneFamilyCarboxypeptidases

CPN2 CPXM1

2.79e-03216821321
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MAG FSTL4 TYRO3 HMCN1

3.17e-03161684593
GeneFamilyClaudins

CLDN15 CLDN7

3.35e-0323682488
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

MAG CD33

4.95e-0328682745
GeneFamilySerpin peptidase inhibitors

SERPINA2 SERPINA1

8.53e-0337682739
CoexpressionFAN_EMBRYONIC_CTX_OLIG

MAG ATP6V0B FA2H TSPAN19 SAMD12 SLC13A3 AQP6 TYRO3 SLC6A9 TECPR2 SCARB1 PCSK7 SMPD1 ADIPOR2

1.71e-0675410414M39037
CoexpressionYOSHIMURA_MAPK8_TARGETS_UP

MAG SLC13A3 GPRC5C APOB CLDN7 AQP8 AQP6 EDN3 LHB SLC6A9 SERPINA1 SLC13A1 NCAN PCSK7 MMS19 PCSK4 NOS1

1.14e-05128110417M1884
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_500

ANPEP AMACR SLC13A3 ACOT1 APOB CLDN7 AQP8 GLB1L2 ACOT4 SERPINA1 SLC13A1 ENTPD2 HDC

4.07e-0839310013gudmap_developingKidney_e15.5_early proxim tubul_500
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

ATP6V0B ANPEP AMACR SLC13A3 ACOT1 GPRC5C APOB CLDN7 AQP8 GLB1L2 ACOT4 SERPINA1 SLC13A1 ENTPD2 HDC

3.86e-0678410015gudmap_developingKidney_e15.5_early proxim tubul_1000
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WNT9A SLC5A7 CLDN15 PTGIS GAREM2 CPXM1 HAS1

2.36e-071781067bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WNT9A SLC5A7 CLDN15 PTGIS GAREM2 CPXM1 HAS1

2.36e-071781067c413861148129be1ee94f2ceb5999840217eebe5
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AMHR2 ANPEP LAT2 CD33 SLC29A1 HDC

2.34e-0616010665d22c86deead516444349d495998e04586be4396
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Mast|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AMHR2 ANPEP LAT2 CD33 SLC29A1 HDC

2.34e-061601066ca212634cf1875238071d1800ecdf34979a553fb
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMHR2 FSTL4 RIPK4 CLDN7 SERPINA1 SLC13A1

3.80e-061741066e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMHR2 FSTL4 RIPK4 CLDN7 SERPINA1 SLC13A1

3.80e-061741066ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTSR2 APOB GLB1L2 ENTPD2 HAS1 SLC7A10

4.33e-0617810666d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTSR2 APOB GLB1L2 ENTPD2 HAS1 SLC7A10

4.33e-061781066d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MAG AQP8 PTGIS CPXM1 HAS1 HDC

4.77e-061811066ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCellPBMC-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

RMI2 TYRO3 GAREM2 DERL3 SLC29A1 DNASE1L2

4.92e-0618210664774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell(3)_Mast_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MAG AMHR2 LAT2 AQP8 CD33 HDC

5.24e-061841066dbfad62b925d835632b39a88ab95bd9af9cb7bee
ToppCell(3)_Mast_cell|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MAG AMHR2 LAT2 AQP8 CD33 HDC

5.24e-061841066482907d3669597e25c8ff3e9a802a31415a0d654
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A34 NTSR2 SLC13A3 NCAN ENTPD2 SLC7A10

5.57e-061861066ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

TNFSF14 WNT9A CLDN15 PTGIS CPXM1 HAS1

6.11e-06189106679bb2593ad5d17f94b17972884241f03a0f43770
ToppCellmetastatic_Brain-MAST_cells|metastatic_Brain / Location, Cell class and cell subclass

MAG AMHR2 LAT2 AQP8 CD33 HDC

6.30e-061901066587bdf020ef222b5b76f0fae0cec3d44bcdac8e6
ToppCellmetastatic_Brain-MAST_cells-MAST|metastatic_Brain / Location, Cell class and cell subclass

MAG AMHR2 LAT2 AQP8 CD33 HDC

6.30e-0619010669dc8afb99de9e4d41f26a41cd8cf1fc0100a54f0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A34 NTSR2 SLC13A3 NCAN ENTPD2 SLC7A10

6.49e-061911066fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTSR2 SLC13A3 NCAN ENTPD2 SLC7A10 PLXNB1

6.69e-061921066261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTSR2 GAREM2 NCAN ENTPD2 SLC7A10 PLXNB1

6.89e-061931066b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NTSR2 GAREM2 NCAN ENTPD2 SLC7A10 PLXNB1

6.89e-06193106640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 CD33 HDC

7.09e-0619410669d7f232ef5f27c28f325edfa6614f479013acbba
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANPEP AMACR SLC25A34 LHFPL7 P2RY11 PIK3R5

7.97e-0619810662b724d2a36843801984d46a969d33149b76c9771
ToppCellCOVID-19-kidney-PCT-S3-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANPEP AMACR SLC13A3 CPN2 SERPINA1 SLC13A1

7.97e-06198106636a60397f49f5381ae377155b73e1891448846b7
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANPEP CLDN15 APOB CLDN7 SERPINA1 SLC13A1

7.97e-0619810662967fb2d94662997bfe932ac299c80d6f182fb48
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANPEP CLDN15 APOB CLDN7 SERPINA1 SLC13A1

7.97e-061981066222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GPRC5C HEATR5A CLDN7 EDN3 PLXNB1 SLC22A31

8.20e-0619910661c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP6V0B LAT2 SERPINA1 CD33 DERL3 SLC29A1

8.44e-062001066a1503bcc774bed9563eda7cf90b8b5bf4405ad85
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATP6V0B LAT2 SERPINA1 CD33 DERL3 SLC29A1

8.44e-06200106625247f8b6ba6cd899ba6bd47e28e090d697e4632
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / Treatment groups by lineage, cell group, cell type

GPRC5C HEATR5A CLDN7 EDN3 PLXNB1 SLC22A31

8.44e-0620010669a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AQP8 SLC18B1 EDN3 AGL PCSK4

1.44e-051291065cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

WNT9A CLDN15 RIPK4 HAS1 PCSK4

3.59e-051561065574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

WNT9A CLDN15 RIPK4 HAS1 PCSK4

3.59e-051561065605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

PTGIS EDN3 HMCN1 ENTPD2 SLC7A10

3.93e-0515910654f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellNS-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FSTL4 TYRO3 CD33 CPXM1 HDC

4.05e-0516010658a4746463ca1976f7d6de803496c851249ced797
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG NTSR2 GLB1L2 ENTPD2 SLC7A10

4.05e-0516010658590281165eab6514a9f6a022b900d4c222c1044
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SH3RF1 SLC25A34 ACOT6 ADORA2A

4.17e-051611065334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SH3RF1 SLC25A34 ACOT6 ADORA2A

4.17e-05161106581d44438e4be4e68a59247e62f02026301a8a0c5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMACR ACOT1 APOB CPN2 ACOT4

4.30e-051621065de0fde4310a56dc96bfc134c44d104993526d9bc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFSF14 STING1 DERL3 HAS1 PIK3R5

4.43e-0516310658028636632c168dc50731d0ebecaf88a70daf81d
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN19 GLA GAREM2 HMCN1 NOS1

4.56e-0516410653cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCellBronchial_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

AMHR2 PGLYRP4 TYRO3 CD33 CPXM1

4.97e-051671065806d1c00c137da0c5f042adf866873eb6dd4bb27
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AMHR2 LAT2 AQP8 CD33 HDC

4.97e-0516710650aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN15 PTGIS GAREM2 CPXM1 HAS1

5.87e-051731065ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN15 PTGIS GAREM2 CPXM1 HAS1

5.87e-0517310653725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellSubstantia_nigra-Macroglia|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MAG FA2H ACOT1 SLC6A9 GAREM2

6.04e-0517410657e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTSR2 NCAN ENTPD2 SLC7A10 PLXNB1

6.37e-051761065ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 CLDN15 PTGIS HMCN1 MMRN2

6.37e-051761065c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD12 CLDN15 PTGIS HMCN1 MMRN2

6.37e-051761065d58ef51002ea50b3037636038214bbb7454cb503
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

SAMD12 PTGIS MMRN2 NOS1 ADIPOR2

6.72e-051781065e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SAMD12 PTGIS MMRN2 NOS1 ADIPOR2

6.72e-051781065363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCellPSB-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

AMHR2 LAT2 AQP8 CD33 HDC

6.72e-05178106545bdbb96094c97756e1b6eebd80eadd8472143f2
ToppCellEndothelial-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SAMD12 PTGIS ADORA2A MMRN2 NOS1

6.72e-0517810652f2602b9305d55f25afa9861dd6c6347ae179337
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AMHR2 PTGIS HMCN1 MMRN2 NOS1

6.90e-0517910658c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPRC5C HEATR5A RIPK4 EDN3 SLC22A31

6.90e-05179106504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 CD33 HDC

7.09e-0518010658bd9e12589bff64987bac30af4d2514ba6f09300
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A3 APOB ACOT4 SLC13A1 HDC

7.27e-051811065bec7076efe94898213a62db72d171d737949977e
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A3 APOB ACOT4 SLC13A1 HDC

7.27e-051811065cf149b30b814cf87c9e923ef502cadf7fe4a3597
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPRC5C HEATR5A RIPK4 EDN3 SLC22A31

7.27e-051811065b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANPEP EDN3 ENTPD2 CPXM1 HAS1

7.47e-051821065e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCellwk_08-11-Mesenchymal-Mesothelial-Late_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AMHR2 ANPEP TNFSF14 ABCA7 HAS1

7.47e-051821065f8257c884393f168f605d371e0840cfca8d3657e
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

GLB1L3 SLC5A7 AQP8 AQP6 HMCN1

7.66e-05183106500a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMHR2 RIPK4 CLDN7 ACOT4 PLXNB1

7.86e-051841065204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP6V0B ANPEP GLA PIK3R5 ADIPOR2

7.86e-051841065fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellwk_20-22-Mesenchymal-Mesothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAG AMHR2 CLDN15 PTGIS HAS1

7.86e-051841065804f8a41cd6b1361448872bf352bf0a38a0fac66
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A3 APOB ACOT4 SLC13A1 HDC

7.86e-0518410653d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMHR2 RIPK4 CLDN7 ACOT4 PLXNB1

7.86e-0518410659365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A3 APOB ACOT4 SLC13A1 HDC

7.86e-05184106545577ff91c3b2b303acd97239dde2463ea7a429c
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMACR WNT9A PTGIS CPT1C CPXM1

7.86e-051841065e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCellwk_20-22-Mesenchymal-Mesothelial-Late_mesothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAG AMHR2 CLDN15 PTGIS HAS1

7.86e-05184106560dd055c2e2e92b838ac649c12e8cccd9c3b1b71
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 RIPK4 CLDN7 ACOT4 PLXNB1

7.86e-0518410657cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 RIPK4 CLDN7 ACOT4 PLXNB1

7.86e-05184106553b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

PTGIS EDN3 MMRN2 NOS1 ADIPOR2

8.06e-051851065ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

TNFSF14 WNT9A CLDN15 PTGIS HAS1

8.06e-05185106523579988036fc1925992c31919750f9b3fe9f790
ToppCell390C-Fibroblasts-Fibroblast-F|390C / Donor, Lineage, Cell class and subclass (all cells)

PTGIS ENTPD2 CPXM1 HAS1 PGA3

8.06e-0518510652c1f14f77faeee2acb388d997c5a27a7fef79be1
ToppCell390C-Fibroblasts-Fibroblast-F-|390C / Donor, Lineage, Cell class and subclass (all cells)

PTGIS ENTPD2 CPXM1 HAS1 PGA3

8.06e-05185106537db8e0b1f59274227f6fc2362167eb44bd080ef
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SH3RF1 SAMD12 PTGIS NOS1 ADIPOR2

8.06e-051851065b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SH3RF1 SAMD12 PTGIS NOS1 ADIPOR2

8.06e-051851065d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTGIS HMCN1 ENTPD2 MMRN2 NOS1

8.06e-051851065a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNFSF14 CLDN15 PTGIS CPXM1 HAS1

8.27e-0518610657812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

ATP6V0B ANPEP GLA PIK3R5 ADIPOR2

8.27e-05186106533d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 HDC

8.48e-051871065bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 HDC

8.48e-05187106509348f1e8bbbca8dca885461937b9b1dd248b034
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 HDC

8.48e-0518710650f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 HDC

8.48e-051871065064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MAG AMHR2 LAT2 CD33 HDC

8.48e-05187106555d5b21517c89736592982af40fd4cd64be62a3c
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

SAMD12 PTGIS MMRN2 NOS1 ADIPOR2

8.70e-051881065eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

CTU2 TNFSF14 HEATR5A LBR AGL

8.70e-0518810658f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAG AMHR2 LAT2 CD33 HDC

8.70e-0518810653fe9d698ff8f540edebf8609e7d42d3f81271edb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

AMHR2 CLDN15 PTGIS ENTPD2 HAS1

8.70e-0518810659655a4c47b644a870017d349b99063e17dbae572
ToppCell3'-Distal_airway-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 CD33 HDC

8.92e-05189106596566f84c796d5b2e31f64090555f2b258f0c9f2
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 CD33 HDC

8.92e-051891065b59cc66f7bb9b72895b775fbcf1ec1dc08610969
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAG AMHR2 LAT2 CD33 HDC

8.92e-0518910657bc6e152fb4fe5cd6db9407929c15843a5d8f8c4
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 CD33 HDC

8.92e-0518910651893765b1e3b306f1e133101c28403070a70c3c8
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 AQP8 HDC

8.92e-051891065f01158bb15df3117fae1271bf8cf8c2501422671
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAG AMHR2 LAT2 CD33 HDC

8.92e-05189106519b639bc6b35fe1d1079f60c8138aa946a95f3bf
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

OGDH ABCA7 SERPINA1 HAS1 SLC29A1

9.14e-051901065b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 TNFSF14 LAT2 SERPINA1 CD33

9.14e-051901065b8c131020d20005cd9f23d26312196f62c958074
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MAG AMHR2 CLDN15 PTGIS HAS1

9.37e-051911065b5374674312ff5803a1d369f5533027532344679
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Micropapillary_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

ANPEP GLB1L3 SLC13A3 GLB1L2

9.59e-0510010648743eadbe35a1fda5ca87d8901de35c573d268ef
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SH3RF1 SAMD12 PTGIS HMCN1 NOS1

9.60e-051921065e911e286da26202853f9650ba3cdefe5a5c9b585
Drugazide

ATP6V0B ANPEP SERPINA2 SERPINA1 OXA1L GUSB ENTPD2 COQ7

1.52e-061801028CID000033558
DrugLeu-ala

ANPEP SLC5A7 APOB PCSK7 PCSK4

1.94e-06461025CID000081721
DrugMetrizamide [31112-62-6]; Up 200; 5uM; PC3; HT_HG-U133A

PGLYRP4 CPN2 HUWE1 EDN3 CD33 ENTPD2 DYRK1B SLC7A10

2.87e-0619610284075_UP
DrugPHA-00745360 [351320-33-7]; Up 200; 1uM; MCF7; HT_HG-U133A

ANPEP LAT2 ABCA7 EDN3 ADORA2A DYRK1B NOS1 HDC

2.98e-0619710283910_UP
DrugAlfadexum

FA2H SLC5A7 HUWE1 GLA AGL

4.34e-06541025CID000024796
DrugC8-ceramide

MAG FA2H APOB ABCA7 GLA GUSB CPT1C SCARB1 PCSK7 SMPD1 NOS1 PIK3R5

7.33e-0655610212CID000002508
Drugdibutyryl cyclic 3',5'-AMP

MAG FA2H APOB AQP8 STING1 ABCA7 EDN3 LHB ADORA2A P2RY11 SCARB1 DNASE1L2

8.02e-0656110212CID000002460
DrugLopac-P-178

ADORA2A P2RY11 ENTPD2 NOS1 SLC29A1

1.27e-05671025CID005478935
DrugSialic acids

MAG APOB SERPINA2 SERPINA1 OXA1L GLA CLEC3A CD33 HAS1

1.74e-053291029CID000349960
DrugX l-1

RIPK4 COQ2 OGDH SERPINA1 GUSB

1.80e-05721025CID000006343
DrugAC1L2EXV

SLC5A7 PCSK7 PCSK4

1.86e-05121023CID000070823
DrugAC1NAX4S

PCSK7 PCSK4

1.99e-0521022CID004459028
Drugpyridinyl imidazole

EDN3 TYRO3 PCSK7 SLC29A1

2.00e-05361024CID000005171
Drugnaphthol-AS-D

ANPEP SERPINA1 GUSB CD33

2.24e-05371024CID000067273
DrugDL-arginine

SRRM1 EDN3 ADORA2A GLA PCSK7 HAS1 NOS1 SLC7A10 HDC

2.47e-053441029CID000000232
Drugpropionyl-L-carnitine

ANPEP EDN3 CPT1C PCSK7

2.49e-05381024CID000107738
Drugsodium sulfate

SLC13A3 AQP8 SLC13A1 GUSB SMPD1

2.83e-05791025CID000024436
DrugAC1Q6PMM

ANPEP SERPINA1 PCSK7 PCSK4

3.07e-05401024CID000003211
Drugmioflazine

ADORA2A ENTPD2 SLC29A1

3.07e-05141023CID000072001
Drugtype-IV

MAG APOB LHB SERPINA1 GLA GUSB CD33 HAS1

3.92e-052811028CID000000906
Drugd Na

COQ2 OGDH EDN3

4.69e-05161023CID000000671
Drugmalondialdehyde

SLC5A7 APOB OGDH GUSB SCARB1 PCSK7 NOS1

4.95e-052131027CID000010964
Drugalaninamide

ANPEP PCSK7 PCSK4

5.67e-05171023CID000350287
Drugpoly(2-vinylpyridine

PCSK7 HAS1 PCSK4

5.67e-05171023CID000007521
DrugATEE

SERPINA1 GUSB PCSK7 PCSK4

5.84e-05471024CID000002004
Drugammonium sulfite

SLC13A3 OGDH

5.94e-0531022CID000025041
DrugmDIC

SLC13A3 OGDH

5.94e-0531022CID000182560
DrugPFPA

GUSB SMPD1 HAS1

6.78e-05181023CID000067742
DrugMet-Ser

SERPINA2 SERPINA1 HDC

6.78e-05181023CID004448381
DrugMan(9)GlcNAc

APOB SERPINA1 GLA AGL

8.07e-05511024CID003081561
Drugoxygen

MAG TNFSF14 FA2H LBR COQ2 OGDH PTGIS OXA1L NOS1 COQ7

8.21e-0549910210CID000000977
DrugAvodart

AMACR SERPINA2 GLA SMPD1

8.71e-05521024CID000152945
DrugAC1N1QTU

ADORA2A P2RY11 ENTPD2 SLC29A1

9.39e-05531024CID003985498
DrugInactin

SLC5A7 EDN3 TYRO3 NOS1

9.39e-05531024CID003032373
Drugphosphocreatinine

OGDH SERPINA1 NOS1

1.09e-04211023CID000071214
Druglithocholate-3-O-glucuronide

APOB GUSB

1.19e-0441022CID000126511
Drugsodium taurodihydrofusidate

LHB PCSK7

1.19e-0441022CID003035005
Drugmethyl myristate

FA2H SERPINA1

1.19e-0441022CID000031284
Drug8-SPT

ADORA2A P2RY11 ENTPD2 NOS1

1.25e-04571024CID000001908
DrugAC1NBU2J

OGDH PCSK7 PCSK4

1.26e-04221023CID004473762
Disease39S ribosomal protein L33, mitochondrial measurement

SERPINA2 SERPINA1

1.18e-0521022EFO_0801332
Diseasecardiovascular event measurement, response to placebo

ACOT6 ACOT4

3.54e-0531022EFO_0006919, EFO_0008344
Diseasealpha globulin measurement, protein measurement

SERPINA2 SERPINA1

7.07e-0541022EFO_0004747, EFO_0004813
Diseasesynaptosomal-associated protein 25 measurement

SERPINA2 SERPINA1

1.18e-0451022EFO_0021858
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A3 SLC13A1

1.18e-0451022DOID:0111668 (implicated_via_orthology)
Diseaseneuropeptide W measurement

SERPINA2 SERPINA1

1.76e-0461022EFO_0801835
Diseaseglucose intolerance (biomarker_via_orthology)

COQ2 ADIPOR2

1.76e-0461022DOID:10603 (biomarker_via_orthology)
Diseasebrain ischemia (implicated_via_orthology)

PTGIS NOS1 SLC29A1

2.42e-04351023DOID:2316 (implicated_via_orthology)
DiseaseX-16935 measurement

ACOT6 ACOT4

2.46e-0471022EFO_0800763
Diseasesleep duration, low density lipoprotein cholesterol measurement

GPRC5C APOB OGDH CLEC3A

2.86e-04911024EFO_0004611, EFO_0005271
DiseaseX-24747 measurement

ACOT6 ACOT4

3.27e-0481022EFO_0022135
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A3 SLC13A1

3.27e-0481022DOID:0050667 (implicated_via_orthology)
Diseaseresponse to darapladib, cardiovascular event measurement

ACOT6 ACOT4

3.27e-0481022EFO_0006919, EFO_0008395
Diseasechymotrypsin-like elastase family member 2A measurement

SERPINA2 SERPINA1

4.19e-0491022EFO_0802399
Diseasealpha-1-antitrypsin measurement

SERPINA2 SERPINA1

4.19e-0491022EFO_0008327
DiseaseX-17653 measurement

ACOT6 ACOT4

4.19e-0491022EFO_0800783
Diseasemean corpuscular hemoglobin concentration

MAG RMI2 GPR152 LBR SERPINA2 ABCA7 SLC6A9 SCARB1 NCAN SLC7A10 SLC29A1 DNASE1L2

4.36e-04110510212EFO_0004528
Diseasegallstones

ANPEP RMI2 CLDN7 SERPINA1

5.47e-041081024EFO_0004210
Diseasefactor VIII measurement, coronary artery disease

APOB SERPINA2 SERPINA1 SCARB1

6.49e-041131024EFO_0001645, EFO_0004630
Diseasecomplement C1q tumor necrosis factor-related protein 1 measurement

SERPINA2 SERPINA1

7.64e-04121022EFO_0801493
DiseaseErythrocyte Mean Corpuscular Hemoglobin Test

GLA AGL

9.00e-04131022C0369183
Diseaseundecenoylcarnitine (C11:1) measurement

ACOT6 ACOT4

9.00e-04131022EFO_0800588
DiseaseFinding of Mean Corpuscular Hemoglobin

GLA AGL

9.00e-04131022C1261502
Diseaseosteoprotegerin measurement

SAMD12 SERPINA1

1.05e-03141022EFO_0005918
DiseaseSpastic Paraplegia, Hereditary

FA2H TECPR2

1.05e-03141022C0037773
Diseasephospholipids:total lipids ratio

APOB SERPINA1 SCARB1 NCAN PCSK7

1.17e-032271025EFO_0020946
Diseasebasophil measurement

SAMD12 SLC7A10 HDC

1.19e-03601023EFO_0803539
Diseaseunipolar depression, autism spectrum disorder

SERPINA2 SERPINA1

1.21e-03151022EFO_0003756, EFO_0003761
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

APOB SERPINA1 NCAN PCSK7

1.99e-031531024EFO_0004611, EFO_0020944
DiseaseAmphetamine-Related Disorders

ADORA2A SLC6A9 NOS1

2.26e-03751023C0236733
DiseaseAmphetamine Abuse

ADORA2A SLC6A9 NOS1

2.26e-03751023C0236807
DiseaseAmphetamine Addiction

ADORA2A SLC6A9 NOS1

2.26e-03751023C0236804
Diseaseectonucleoside triphosphate diphosphohydrolase 5 measurement

SERPINA2 SERPINA1

2.38e-03211022EFO_0008115
Diseaseautism spectrum disorder symptom

CTU2 CBLN1

2.86e-03231022EFO_0005426
Diseasenephrotic syndrome (biomarker_via_orthology)

APOB NOS1

3.11e-03241022DOID:1184 (biomarker_via_orthology)
Diseaselipoprotein measurement, phospholipid measurement

APOB SCARB1 NCAN

3.23e-03851023EFO_0004639, EFO_0004732

Protein segments in the cluster

PeptideGeneStartEntry
SFAGLEPMGLLWALE

ACOT1

71

Q86TX2
SLQWNMLRVLPAGLF

CPN2

271

P22792
LSFAIGLTPMLGWNN

ADORA2A

131

P29274
GLAGFLLLWSAVLIM

SLC7A10

116

Q9NS82
GAPGLLWMGLVLALA

SMPD1

26

P17405
MPSSVSWGILLLAGL

SERPINA1

1

P01009
LSLWEAPRGQNMLDG

AMACR

201

Q9UHK6
LGGVASLLLSFVWMP

CUTA

11

O60888
MWGLLLALAAFAPAV

CPXM1

1

Q96SM3
MNKGWLELESDPGLF

BAP1

1

Q92560
SFAGLQPMGLLWALE

ACOT6

71

Q3I5F7
GWNDPDMLVIGNFGL

GLA

261

P06280
LPYWVSQLLGGMLGA

AQP8

111

O94778
LPDFNAGAMENWGLV

ANPEP

346

P15144
WALMGFSLLLGNSIL

DERL3

156

Q96Q80
LGTPYDLAIDMWSLG

DYRK1B

286

Q9Y463
MGGLSPTLYWLGNFL

ABCA7

1571

Q8IZY2
MLGSLGLWALLPTAV

AMHR2

1

Q16671
PGESIWMALVLLGLF

AMHR2

141

Q16671
SGIALLIMGSFVPWL

ADIPOR2

221

Q86V24
PNYLGDLIMALAWSL

LBR

546

Q14739
SWPSLLGDMLADAIN

HDC

86

P19113
WLGVPALALFMSSLE

FHIP1B

291

Q8N612
FLLLGIPGLESMHLW

OR52E1

11

Q8NGJ3
PAMLWGLSLFLNLPG

CRELD1

11

Q96HD1
KPWLSGFSVAMLGAL

COQ2

276

Q96H96
AAGWVLAALLAMPTL

P2RY11

151

Q96G91
NDWDFPRNGLLMPLL

MAGEB1

191

P43366
ALPLFWIMISASRGG

MAG

6

P20916
LGPSSGLLVDWLEML

INTS1

1611

Q8N201
VALSWAASLGLALPM

NTSR2

156

O95665
ALGKMPDAVNFWLGE

JMJD7

156

P0C870
MILSLLFSLGGPLGW

MMRN2

1

Q9H8L6
AVEAAAPMGALWGLV

MMS19

6

Q96T76
CSEMDLGGLPSWLLQ

GLB1L3

166

Q8NCI6
LLLSMGGAWASREPL

LHB

11

P01229
LLPLLWAGALAMDPN

CD33

6

P20138
WALGYMLNLTNLIPA

ENTPD2

436

Q9Y5L3
GMIALALEANPFLTW

PCSK4

381

Q6UW60
AGLFLLVPWVMGLAG

PCSK7

26

Q16549
MPALGPALLQALWAG

PLXNB1

1

O43157
QLLGLLMLWVPGSSA

IGKV2D-26

6

A0A0A0MRZ7
MLPWLLVFSALGIQA

PGLYRP4

1

Q96LB8
LLGLPANGLMAWLAG

GPR152

41

Q8TDT2
QNLLEFMHVDLGLPW

OXA1L

126

Q15070
LPDGTGEFLDAWLML

HUWE1

1191

Q7Z6Z7
PMGDLGQLLFLEWDA

NDUFA9

96

Q16795
MNLPTESGELWILGD

PGA3

351

P0DJD8
SMAWLRDGQPLGLDA

HMCN1

3466

Q96RW7
WYGLPAVSNMLLEIG

NOS1

566

P29475
VMLLLLGAFLGAWPA

GPRC5C

216

Q9NQ84
QLAGAAWAAPFLAMV

OR6V1

141

Q8N148
PGLFMLGTFLWSLIE

FA2H

216

Q7L5A8
GFAMASPNALVLWEA

OGDH

731

Q02218
LAWFLQLDPSLGLME

CPT1C

71

Q8TCG5
MPFSVSWGVLLLAGL

SERPINA2

1

P20848
GLLIFDASSSWGPQM

APOB

1451

P04114
QAGWLLISALMTLGP

HEATR5A

551

Q86XA9
LMLNGWPVISAFAGD

CBLN1

131

P23435
MGGPRALLAALWALE

DNASE1L2

1

Q92874
GDGSRWNYALLVPML

CCDC127

21

Q96BQ5
MEPGLWLLFGLTVTS

EDN3

1

P14138
FWVGPLMGALLASLI

AQP6

216

Q13520
MARGSAVAWAALGPL

GUSB

1

P08236
LMPLWNVLGFALGAG

COQ7

111

Q99807
TLLGASLPAALGWMD

FSTL4

11

Q6MZW2
GLLMLGVTLPNSYWR

CLDN15

16

P56746
LILGLMTWAYAAGVP

HAS1

31

Q92839
SEMDLGGLPSWLLQD

GLB1L2

141

Q8IW92
VMLLGGWLLLAFNAI

LHFPL7

71

Q6ICI0
QGLGALMSGLLLLFW

SLC22A31

246

A6NKX4
MPWDIAILVGGGFAL

SLC13A1

431

Q9BZW2
PWNIILLLGGGFAMA

SLC13A3

426

Q8WWT9
MTNLALGRGAFLAWD

CTU2

276

Q2VPK5
MNLPTESGELWILGD

PGA4

351

P0DJD7
MSSGTELLWPGAALL

LAT2

1

Q9GZY6
LDPSIMDFALQGNLW

FOXN4

421

Q96NZ1
AGLAGLRWSMGAFPL

GAREM2

6

Q75VX8
LDSFLLLMLGGIPWQ

SLC5A7

241

Q9GZV3
PFTWMLALLGLSQAL

STING1

116

Q86WV6
AAAGRGPLDLAAVWM

RMI2

46

Q96E14
LPEDSWLVALAGGMI

SLC25A34

201

Q6PIV7
QGLWALISGLAMGLF

SLC18B1

411

Q6NT16
GNMGPAAFWLLLFLL

PTGIS

286

Q16647
MGAPFVWALGLLMLQ

NCAN

1

O14594
LPLLWFAESGAMEGE

SCARB1

411

Q8WTV0
LLTQGTLLLPDGWMD

SAMD12

151

Q8N8I0
WARGMPFSELAGLSG

SKIV2L

1176

Q15477
SLGNEQWEFTLGMPL

PHAF1

11

Q9BSU1
MEGDGGTPWALALLR

RIPK4

1

P57078
LGLGTLLPWNFFMTA

SLC29A1

21

Q99808
NWAEGMLADKIGIFP

SH3RF1

236

Q7Z6J0
SFAGLEPMGLLWALE

ACOT4

71

Q8N9L9
LQLLGFSMALLGWVG

CLDN7

6

O95471
SLPGVNDFWLGINDM

CLEC3A

121

O75596
FLGQLSMDLEGLEWL

LINC00477

81

Q96M19
VGWNMQLLPAGLASF

CLEC18B

106

Q6UXF7
VGWNMQLLPAGLASF

CLEC18C

106

Q8NCF0
LGMLDPWYERNVLGL

PIK3R5

611

Q8WYR1
LMGAGLAVQGWFLLQ

TNFSF14

46

O43557
FMGELWPLLLSAQEN

SRRM1

101

Q8IYB3
PFMWSNLGIGLAISL

ATP6V0B

46

Q99437
PGWAVAIGFLMALSS

SLC6A9

606

P48067
AGLLKPDQFAESWMG

TECPR2

791

O15040
MLDGSPLARWLAAAF

WNT9A

1

O14904
LLFMGFGAWLLLDRN

TSPAN19

26

P0C672
ASVAWMPGADGRALL

TYRO3

241

Q06418
PNWSALKYAGLQGLM

AGL

926

P35573