Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentintercalated disc

TJP1 SCN1A SCN2A

5.45e-0468493GO:0014704
GeneOntologyCellularComponentcentriole

CEP350 CEP104 AHI1 STIL

7.03e-04172494GO:0005814
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A

7.16e-0417492GO:0001518
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A

9.95e-0420492GO:0033268
GeneOntologyCellularComponentcell-cell contact zone

TJP1 SCN1A SCN2A

1.40e-0394493GO:0044291
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A

2.10e-0329492GO:0043194
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A

2.10e-0329492GO:0034706
HumanPhenoAbnormal antral follicle count

BNC1 NOBOX

3.14e-053172HP:0033084
HumanPhenoReduced antral follicle count

BNC1 NOBOX

3.14e-053172HP:0033085
DomainCCDC74_C

CCDC74B CCDC74A

6.47e-062482PF14917
DomainCCDC74_C

CCDC74B CCDC74A

6.47e-062482IPR029422
DomainCCDC74

CCDC74B CCDC74A

6.47e-062482IPR033226
DomainPWWP

BRPF3 ZCWPW1 NSD1

1.76e-0520483SM00293
DomainPWWP

BRPF3 ZCWPW1 NSD1

2.72e-0523483PF00855
DomainPWWP_dom

BRPF3 ZCWPW1 NSD1

2.72e-0523483IPR000313
DomainPWWP

BRPF3 ZCWPW1 NSD1

3.10e-0524483PS50812
DomainNa_trans_cytopl

SCN1A SCN2A

9.64e-056482PF11933
DomainNa_trans_cytopl

SCN1A SCN2A

9.64e-056482IPR024583
DomainNa_channel_asu

SCN1A SCN2A

2.87e-0410482IPR001696
DomainNa_trans_assoc

SCN1A SCN2A

2.87e-0410482IPR010526
DomainNa_trans_assoc

SCN1A SCN2A

2.87e-0410482PF06512
DomainChannel_four-helix_dom

KCNA6 SCN1A SCN2A

4.23e-0457483IPR027359
Domain-

KCNA6 SCN1A SCN2A

4.23e-04574831.20.120.350
DomainZF_MATRIN

TRIT1 ZNF638

9.64e-0418482PS50171
Domainzf-C2H2_jaz

TRIT1 ZNF638

1.45e-0322482PF12171
DomainZnf_C2H2_jaz

TRIT1 ZNF638

1.45e-0322482IPR022755
DomainChromo_domain

CHD1 CHD6

1.72e-0324482IPR023780
DomainChromo

CHD1 CHD6

2.02e-0326482PF00385
DomainCHROMO_2

CHD1 CHD6

2.34e-0328482PS50013
DomainCHROMO_1

CHD1 CHD6

2.34e-0328482PS00598
DomainZnF_U1

TRIT1 ZNF638

2.51e-0329482SM00451
DomainZnf_U1

TRIT1 ZNF638

2.51e-0329482IPR003604
DomainSNF2_N

CHD1 CHD6

3.05e-0332482PF00176
DomainSNF2_N

CHD1 CHD6

3.05e-0332482IPR000330
DomainChromodomain-like

CHD1 CHD6

3.05e-0332482IPR016197
DomainIon_trans_dom

KCNA6 SCN1A SCN2A

3.14e-03114483IPR005821
DomainIon_trans

KCNA6 SCN1A SCN2A

3.14e-03114483PF00520
DomainCHROMO

CHD1 CHD6

3.25e-0333482SM00298
DomainChromo/shadow_dom

CHD1 CHD6

3.25e-0333482IPR000953
DomainDNA/RNA_helicase_DEAH_CS

CHD1 CHD6

3.65e-0335482IPR002464
DomainDEAH_ATP_HELICASE

CHD1 CHD6

4.29e-0338482PS00690
DomainSET

NSD1 PRDM14

4.98e-0341482PF00856
DomainSET

NSD1 PRDM14

6.23e-0346482SM00317
DomainZnf_FYVE_PHD

BRPF3 NSD1 PRDM14

6.38e-03147483IPR011011
DomainSET_dom

NSD1 PRDM14

7.32e-0350482IPR001214
DomainSANT

GON4L CHD6

7.32e-0350482SM00717
DomainSET

NSD1 PRDM14

7.32e-0350482PS50280
DomainSANT/Myb

GON4L CHD6

7.90e-0352482IPR001005
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

TJP1 POP1 ZNF638 GON4L PDCD11 EBNA1BP2 RRBP1 USP48

7.60e-0839449827248496
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

CEP350 POP1 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1

3.57e-0748349836912080
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

NSD1 CHD1 CHD6 EBNA1BP2 BCOR

4.71e-0710949533554859
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TJP1 MKI67 NSD1 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1 BCOR HMGN4

7.17e-07954491036373674
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

POP1 TIMM50 MKI67 NSD1 ZNF638 PDCD11 CHD6 EBNA1BP2 RRBP1 BCOR HMGN4

1.44e-061294491130804502
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.94e-06249229649454
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.94e-06249210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.94e-06249219694741
Pubmed

Thymidine kinase 1 expression in ovarian serous adenocarcinoma is superior to Ki-67: A new prognostic biomarker.

TK1 MKI67

1.94e-06249228651488
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.94e-0624921317301
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.94e-06249233096315
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.94e-06249231439038
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.94e-06249226311622
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

1.94e-06249215249644
Pubmed

Expression of cell proliferating genes in patients with non-small cell lung cancer by immunohistochemistry and cDNA profiling.

TK1 MKI67

1.94e-06249215809747
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

1.94e-06249221377452
Pubmed

CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.

CCDC74B CCDC74A

1.94e-06249231521166
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

1.94e-06249230693367
Pubmed

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.

TJP1 MKI67 PDCD11

2.11e-061849327558965
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TJP1 POP1 MKI67 NSD1 ZNF638 PDCD11 CHD1 EBNA1BP2

3.39e-0665349822586326
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

5.83e-06349228784306
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

5.83e-06349232185219
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A

5.83e-06349212610651
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

5.83e-06349232005694
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A

5.83e-06349223859570
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A

5.83e-06349218784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A

5.83e-06349217544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A

5.83e-06349232845893
Pubmed

[Expression of HER2/neu in meningiomas: an immunohistochemistry and fluorescence in situ hybridization study].

TK1 MKI67

5.83e-06349220450760
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A

5.83e-06349228518218
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

5.83e-06349219270815
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

5.83e-06349225155934
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A

5.83e-06349217928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A

5.83e-06349214973256
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CEP350 TJP1 MKI67 STIL BCOR

6.20e-0618449532908313
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

TJP1 POP1 MKI67 ZNF638 PDCD11 EBNA1BP2

7.16e-0633249625693804
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CEP350 MAGED1 TJP1 TK1 ZNF638 CHD1 CHD6 RRBP1

7.88e-0673349834672954
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

CEP350 TJP1 TIMM50 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1

1.14e-05102449924711643
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A

1.16e-05449217537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A

1.16e-05449235031483
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SCN1A SCN2A

1.16e-05449226637798
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A

1.16e-05449229578003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A

1.16e-05449221156207
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A

1.16e-05449235801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A

1.16e-0544928974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A

1.94e-0554921679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A

1.94e-0554928812438
Pubmed

Maternal malnourishment induced upregulation of fetuin-B blunts nephrogenesis in the low birth weight neonate.

MKI67 FETUB

1.94e-05549230189195
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A

1.94e-05549224337656
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

CEP104 BRPF3 IFIT1B AFF3 NSD1 TMOD2 PCMTD1 MYLK2

1.96e-0583249836724073
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MKI67 NSD1 CHD1 CHD6 EBNA1BP2 BCOR USP48

2.19e-0560849736089195
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

TJP1 POP1 TIMM50 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2

2.23e-0584749835850772
Pubmed

DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex.

POP1 EBNA1BP2 RRBP1

2.32e-053949325825154
Pubmed

Human transcription factor protein interaction networks.

MAGED1 TIMM50 MKI67 ZNF638 TMOD2 GON4L PDCD11 CHD6 EBNA1BP2 BCOR

2.53e-051429491035140242
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

AFF3 CHD1 BCOR

2.70e-054149320431927
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

TIMM50 MKI67 CHD1 EBNA1BP2 RRBP1

2.88e-0525349529911972
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A

2.91e-05649223652591
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

MAGED1 POP1 MKI67 CHD1 CHD6 EBNA1BP2 RRBP1

3.52e-0565549735819319
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MRTFB MAGED1 POP1 NSD1 GON4L PDCD11 CHD1 CHD6 BCOR MYLK2

3.75e-051497491031527615
Pubmed

Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice.

TJP1 MKI67

4.07e-05749219551907
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A

4.07e-05749225818041
Pubmed

Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells.

TJP1 MKI67

4.07e-05749233129760
Pubmed

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway.

TJP1 MKI67

4.07e-05749221947081
Pubmed

Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity.

TJP1 MKI67

4.07e-05749228822114
Pubmed

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton.

CEP350 TMOD2 STIL

4.35e-054849327872092
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

MRTFB TJP1 MKI67 ZNF638 CHD1 EBNA1BP2 RRBP1 BCOR

4.46e-0593449833916271
Pubmed

Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

TJP1 MKI67

5.42e-05849218084280
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

TK1 AFF3 POP1 TIMM50 CHD1 SNX19

6.79e-0549649631343991
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A

6.96e-05949216382098
Pubmed

KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2.

MAGED1 TIMM50

6.96e-05949231685809
Pubmed

An essential role for Cmtr2 in mammalian embryonic development.

IFIT1B MKI67

6.96e-05949239094818
Pubmed

The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion.

TJP1 MKI67

6.96e-05949217360635
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A

6.96e-05949215746173
Pubmed

Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures.

TJP1 MKI67

6.96e-05949218816447
Pubmed

Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome.

AHI1 MKI67

6.96e-05949221623382
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

TK1 POP1 TIMM50 MKI67 PDCD11 CHD1 CHD6 EBNA1BP2 RRBP1

8.20e-05131849930463901
Pubmed

FoxL1+ mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development.

TJP1 MKI67

8.69e-051049233993983
Pubmed

Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.

TJP1 MKI67

8.69e-051049233896079
Pubmed

Common variants associated with general and MMR vaccine-related febrile seizures.

SCN1A SCN2A

8.69e-051049225344690
Pubmed

Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula.

TJP1 MKI67

8.69e-051049228882402
Pubmed

NOVA2 regulates neural circRNA biogenesis.

AFF3 PCMTD1

8.69e-051049234157123
Pubmed

Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves.

TJP1 MKI67

8.69e-051049216543498
Pubmed

Maternal vitamin C regulates reprogramming of DNA methylation and germline development.

MKI67 NOBOX

8.69e-051049231485074
Pubmed

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.

SCN1A SCN2A

8.69e-051049220602612
Pubmed

Ccdc85c encoding a protein at apical junctions of radial glia is disrupted in hemorrhagic hydrocephalus (hhy) mice.

TJP1 MKI67

8.69e-051049222056358
Pubmed

Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2.

TJP1 MKI67

8.69e-051049219363157
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

MAGED1 TJP1 STIL SNX19

9.61e-0516949431462741
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TK1 POP1 TIMM50 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1

1.00e-04135349929467282
Pubmed

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.

TJP1 PDCD11 EBNA1BP2 RRBP1

1.03e-0417249426336360
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

POP1 TIMM50 MKI67 PDCD11 EBNA1BP2

1.05e-0433349536779763
Pubmed

FASN-dependent de novo lipogenesis is required for brain development.

TJP1 MKI67

1.06e-041149234996870
Pubmed

The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.

TJP1 MKI67

1.06e-041149220181838
Pubmed

The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis.

TJP1 MKI67

1.06e-041149224348274
Pubmed

EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins.

TJP1 MKI67

1.27e-041249222819673
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A

1.27e-04124928169823
Pubmed

Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration.

MKI67 BCOR

1.27e-041249236070393
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A

1.27e-041249230175250
Pubmed

Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.

MRTFB MKI67

1.50e-041349229114040
Pubmed

Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex.

TJP1 MKI67

1.50e-041349230858607
Pubmed

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.

TJP1 MKI67

1.50e-041349218849982
InteractionCUL7 interactions

BRPF3 TJP1 TK1 TIMM50 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1 SNX19

4.46e-068454911int:CUL7
InteractionH3C1 interactions

POP1 MKI67 NAV3 NSD1 ZNF638 CHD1 EBNA1BP2 RRBP1 USP48 HMGN4 MYLK2

8.21e-069014911int:H3C1
InteractionUSP36 interactions

CEP350 BRPF3 POP1 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1

1.21e-05599499int:USP36
InteractionNUP43 interactions

MRTFB MKI67 NSD1 GON4L PDCD11 CHD1 CHD6 EBNA1BP2 BCOR

1.70e-05625499int:NUP43
InteractionSMC5 interactions

TJP1 TK1 MKI67 NSD1 ZNF638 PDCD11 CHD1 EBNA1BP2 RRBP1 BCOR HMGN4

2.18e-0510004911int:SMC5
InteractionDCAF4 interactions

CEP350 MAGED1 TJP1 PDCD11 CHD1 CHD6 EBNA1BP2

3.37e-05378497int:DCAF4
InteractionPLK4 interactions

CEP350 MAGED1 MKI67 TMOD2 STIL

3.55e-05154495int:PLK4
InteractionPES1 interactions

BRPF3 POP1 MKI67 EBNA1BP2 RRBP1 MYLK2

3.66e-05258496int:PES1
InteractionTERF2IP interactions

TJP1 MKI67 NSD1 ZNF638 CHD1 BCOR USP48 HMGN4

5.05e-05552498int:TERF2IP
InteractionH2BC3 interactions

TJP1 POP1 GON4L EBNA1BP2 RRBP1 USP48 HMGN4

5.30e-05406497int:H2BC3
InteractionMAP3K14 interactions

TIMM50 MKI67 PDCD11 EBNA1BP2 RRBP1

5.53e-05169495int:MAP3K14
InteractionTWIST1 interactions

NSD1 CHD1 CHD6 EBNA1BP2 BCOR

5.69e-05170495int:TWIST1
InteractionNOP56 interactions

POP1 MKI67 NSD1 PDCD11 CHD1 EBNA1BP2 BCOR MYLK2

6.33e-05570498int:NOP56
InteractionCEP104 interactions

CEP350 CEP104 TJP1 RRBP1

6.47e-0589494int:CEP104
InteractionSIRT7 interactions

MAGED1 TJP1 POP1 MKI67 NSD1 ZNF638 PDCD11 CHD1 EBNA1BP2

6.62e-05744499int:SIRT7
InteractionH2BC8 interactions

MKI67 NSD1 GON4L CHD1 CHD6 EBNA1BP2 BCOR USP48

6.81e-05576498int:H2BC8
InteractionPRC1 interactions

TJP1 POP1 MKI67 ZNF638 TMOD2 PDCD11 CHD1 EBNA1BP2 HMGN4 LACTBL1

9.68e-059734910int:PRC1
InteractionMB21D2 interactions

CEP104 AHI1 MKI67 STIL

1.19e-04104494int:MB21D2
InteractionSNRNP40 interactions

POP1 MKI67 GON4L PDCD11 CHD1 EBNA1BP2 BCOR USP48

1.37e-04637498int:SNRNP40
InteractionSUZ12 interactions

TIMM50 MKI67 ZNF638 PDCD11 CHD1 EBNA1BP2 ZNF831 PRDM14

1.48e-04644498int:SUZ12
InteractionSCN4B interactions

SCN1A SCN2A

1.61e-048492int:SCN4B
InteractionH2AC4 interactions

TJP1 POP1 ZNF638 GON4L PDCD11 EBNA1BP2 USP48

2.08e-04506497int:H2AC4
InteractionTOLLIP interactions

MAGED1 TJP1 MKI67 PDCD11 CHD6 USP48

2.21e-04358496int:TOLLIP
InteractionUSP7 interactions

SP4 MAGED1 SCN2A POP1 NSD1 ZNF638 GON4L STIL BCOR PRDM14 FETUB

2.52e-0413134911int:USP7
InteractionCENPA interactions

NSD1 PDCD11 CHD1 CHD6 EBNA1BP2 USP48

2.92e-04377496int:CENPA
Cytoband2q24.3

SCN1A SCN2A

1.33e-04164922q24.3
Cytoband1p36.12

USP48 LACTBL1

8.06e-04394921p36.12
Cytoband2q21.1

CCDC74B CCDC74A

1.78e-03584922q21.1
GeneFamilyPWWP domain containing

BRPF3 ZCWPW1 NSD1

6.21e-06223031147
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A

9.51e-0593021203
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GON4L CHD6

3.48e-0353302532
GeneFamilyPHD finger proteins

BRPF3 NSD1

9.74e-039030288
CoexpressionGSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN

TK1 MKI67 STIL RRBP1 NOBOX

3.49e-05199495M5983
CoexpressionGSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_UP

IFIT1B MKI67 TMOD2 PCMTD1 DENND2B

3.49e-05199495M7800
CoexpressionGSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN

TRIT1 AHI1 MAGED1 AFF3 RRBP1

3.49e-05199495M4964
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 NSD1 ZNF638 CHD1 RRBP1

1.79e-061844951154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 NSD1 ZNF638 CHD1 RRBP1

1.83e-061854957adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 MRTFB SCN1A SCN2A AFF3

2.56e-06198495c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 MRTFB SCN1A SCN2A AFF3

2.56e-061984956d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 MRTFB SCN1A SCN2A AFF3

2.56e-061984958ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 MRTFB SCN1A SCN2A AFF3

2.56e-061984954ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AFF3 TIMM50 FNDC4 DENND2B

2.61e-051564946c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCellCOVID-19_Severe-multiplets|World / disease group, cell group and cell class

TK1 CCDC74A MKI67 MYLK2

3.10e-051634946db4271c2d47a9c333964f36d2c32207115e52cd
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TK1 MKI67 CXCL16 STIL

3.33e-05166494bb8135119dc37fdbba476599a56d368f422688dc
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIT1 ZCWPW1 AFF3 USP48

3.65e-05170494070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TK1 MKI67 FNDC4 STIL

3.73e-051714941efce222989460bb59bd9fa955e7d9a60c73994c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGBP TK1 MKI67 EBNA1BP2

3.82e-05172494fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZCWPW1 TK1 MKI67 STIL

3.82e-051724947c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

TRIT1 CCDC74A MKI67 STIL

3.91e-0517349462e0c18cfed9645e34a9d7029c94a8554f773714
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 STIL MYLK2

4.46e-051794949383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell3'_v3-blood-Lymphocytic_B_plasma-Plasmablasts|blood / Manually curated celltypes from each tissue

TK1 MKI67 STIL MYLK2

4.46e-051794947d3bd1f9e126a4a9e0a84720a6cc0b3d235e65ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TK1 SCN2A MKI67 STIL

4.56e-05180494401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 NSD1 ZNF638 CHD1

4.76e-05182494f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FCGBP TK1 MKI67 CXCL16

4.97e-0518449497ae5ffecf90df42cc8eea2a247ca589f35a4783
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TK1 CCDC74A MKI67 STIL

5.07e-0518549447c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

CEP350 AHI1 CCDC74A STIL

5.07e-051854949a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TK1 TOPAZ1 MKI67 STIL

5.07e-0518549457c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

FCGBP TK1 MKI67 STIL

5.29e-05187494265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZCWPW1 TK1 MKI67 STIL

5.40e-051884940ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TK1 MKI67 EBNA1BP2 RRBP1

5.74e-05191494b6cc0a9ced40ce5f80065d24d5bc20e3838a7682
ToppCellCOVID-19_Severe-Lymphoid_P|COVID-19_Severe / Disease group, lineage and cell class

MAGED1 TK1 MKI67 RRBP1

5.86e-051924943d0240491296757b3125f6e861bbaca06bbc5068
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

FCGBP TJP1 AFF3 FNDC4

5.86e-05192494f18da8db573e584c8b90df0814afcf020360108e
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 CHD6 RRBP1 PCMTD1

5.86e-05192494916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19_Severe-Lymphoid_P-Plasmablast|COVID-19_Severe / Disease group, lineage and cell class

MAGED1 TK1 MKI67 RRBP1

5.86e-0519249490af8dad4e6f80b5ecd62027deeb2e4cea6b24bb
ToppCellCOVID-19_Severe-Plasmablast|World / disease group, cell group and cell class

MAGED1 TK1 MKI67 RRBP1

5.86e-05192494a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 TJP1 NAV3 RRBP1

5.98e-0519349406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAGED1 TK1 MKI67 RRBP1

5.98e-05193494227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAGED1 TK1 MKI67 RRBP1

5.98e-0519349438bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 TJP1 NAV3 RRBP1

5.98e-051934949c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF638 CHD6 RRBP1 PCMTD1

5.98e-05193494e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 TJP1 NAV3 RRBP1

5.98e-05193494a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAGED1 TK1 MKI67 RRBP1

5.98e-05193494ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAGED1 TK1 MKI67 RRBP1

5.98e-051934948f57b0473a2c2c07f83e5fe70f16862b1bb3b514
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 TJP1 NAV3 RRBP1

5.98e-05193494b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAGED1 TK1 MKI67 RRBP1

5.98e-051934943ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCellsevere-Plasmablast|World / disease stage, cell group and cell class

MAGED1 TK1 MKI67 RRBP1

6.10e-0519449449e8f90db571a89b8a26aef31fcacd66429fed11
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AHI1 MRTFB SCN2A AFF3

6.35e-05196494676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCelldistal-Hematologic-Proliferating_NK/T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KCNA6 TK1 MKI67 STIL

6.47e-0519749404b10879e48c101d1de449db0bc6b6484090b965
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CEP350 AHI1 ZNF638 RRBP1

6.47e-051974940fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellILEUM-inflamed-(5)_Plasmablasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TK1 MKI67 EBNA1BP2 RRBP1

6.47e-051974948710a586fc91cf664032a12e4d2a0399b370cbcb
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CEP350 TJP1 CHD1 EBNA1BP2

6.60e-0519849476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TK1 MKI67 STIL RRBP1

6.60e-051984942d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-B-Plasmablast|COVID-19_Severe / Disease, condition lineage and cell class

MAGED1 TK1 MKI67 RRBP1

6.73e-05199494e6422b65e22e5aa8dfaebdae5be76dd78b978604
ToppCellMild/Remission-Developping_Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 STIL RRBP1

6.73e-0519949458c772ec763109a4009f52424fbb214fc23d0c09
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

TK1 MKI67 STIL DENND2B

6.73e-05199494e222b90caf45904d8f763574e7b6aac13333df92
ToppCellMild/Remission-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 STIL RRBP1

6.73e-051994941dda6116de639140c2d6f5012b7ab9ad0f737ae1
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

TK1 MKI67 STIL MYLK2

6.86e-05200494415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

TK1 MKI67 STIL MYLK2

6.86e-05200494e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FCGBP TK1 MKI67 CXCL16

6.86e-052004945f1de1f9305e1784c12d526f6c8bdd7d56229f9b
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

TK1 MKI67 STIL RRBP1

6.86e-05200494b0d708715f09ec1f67fdef3b100a91c8ff2747a7
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

AHI1 MRTFB SCN2A AFF3

6.86e-0520049448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellSevere-Developping_Plasmablast|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 STIL RRBP1

6.86e-052004946d0cd00e52568d23597cc2a4059bd967d7d2dab5
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

TK1 MKI67 CXCL16 STIL

6.86e-052004944e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellSevere-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 STIL RRBP1

6.86e-0520049480639e0d2ddaae36ac7634a4f03e8809af7316e3
ToppCellControl-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TK1 MKI67 FNDC4

3.12e-04120493695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCellileum-Epithelial_Stem_Cells|ileum / shred on tissue and cell subclass

FCGBP MKI67 PDCD11

3.60e-04126493a8ed48cbd1e207fd1aaad454fda9f329eb22aa83
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCN1A FNDC4 ZNF831

3.77e-04128493003e133469899a9abe3a7f6d7f580583b281f412
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

4.03e-04131493f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellEnterocyte-C_02|Enterocyte / shred on cell type and cluster

AHI1 MKI67 CHD6

4.50e-04136493daf11618c65e8fa2d77001b5c277d534cc012a4b
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_only / Treatment groups by lineage, cell group, cell type

TK1 MKI67 HMGN4

4.69e-041384936ddd50e44a3914596b4cd61ae64a987119fe7979
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.10e-041424937bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.10e-0414249392bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.10e-04142493328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 STIL BCOR

5.10e-04142493be63c48794a227ea55978524c0f5935342fc455e
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.10e-0414249394774d3e598d074f48146b0b094705dc48af5a1f
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZCWPW1 KCNA6 SNX19

5.20e-04143493b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZCWPW1 MAGED1 CCDC74A

5.64e-041474932d9044ddf01b6838a44a4518b442d7e7cb0bf910
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.75e-04148493b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

5.75e-041484932a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

TRIT1 TOPAZ1 AFF3

5.98e-04150493b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BRPF3 FNDC4 BCOR

6.21e-041524930fda8980b10ce16179dea92301db74d728f41794
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

6.33e-04153493d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

6.33e-04153493e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

6.33e-0415349354a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

6.33e-0415349369a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TK1 MKI67 STIL

6.58e-04155493969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellCOPD-Myeloid-DC_Langerhans|COPD / Disease state, Lineage and Cell class

FCGBP AFF3 FNDC4

6.95e-0415849371af1319eec34bf7bc9361ec9ef720c280ce97d1
ToppCellCOPD-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

FCGBP AFF3 FNDC4

7.21e-041604931b73a14ad6546d9f2812c19081278a79260abeae
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POP1 MKI67 ZNF831

7.21e-041604935c931e859acf67c1c8664941e0e44d195f8ba75b
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

7.34e-041614930dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

7.34e-04161493b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

7.34e-04161493efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TK1 MKI67 STIL

7.34e-0416149328d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

TJP1 NAV3 CXCL16

7.34e-041614937df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

TJP1 NAV3 CXCL16

7.34e-041614934e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCWPW1 MKI67 STIL

7.48e-0416249304a96442e0fcdb6a65b9e45044021677f9f53d38
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCWPW1 MKI67 STIL

7.48e-041624937adb3e279526e1f21033c10af0a0058258f21842
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TK1 MKI67 STIL

7.61e-041634933efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TK1 MKI67 STIL

7.75e-04164493fb18b863152fb3109e2224c791c84c6371680a4e
ToppCellCOPD-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

FCGBP AFF3 FNDC4

7.75e-04164493a07c6e13c07a90bc37db0915eb14931eb8309a1e
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZCWPW1 TK1 STIL

7.88e-0416549366f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A NAV3 TMOD2

7.88e-04165493347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A NAV3 TMOD2

7.88e-041654931890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A NAV3 TMOD2

7.88e-04165493507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A NAV3 TMOD2

7.88e-0416549339a25be081a5d59c7cf107a997d352793d5025fb
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

CEP350 TJP1 ZNF638

2.56e-0450273GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
DiseaseJOUBERT SYNDROME 17

CEP104 AHI1

2.37e-055462C3553264
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

4.97e-057462C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

4.97e-057462C0751057
DiseaseMental Retardation, Psychosocial

AHI1 SCN1A NSD1 GON4L

6.60e-05139464C0025363
DiseaseProfound Mental Retardation

AHI1 SCN1A NSD1 GON4L

6.60e-05139464C0020796
DiseaseMental deficiency

AHI1 SCN1A NSD1 GON4L

6.60e-05139464C0917816
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

8.50e-059462C3502809
DiseaseFebrile Convulsions

SCN1A SCN2A

8.50e-059462C0009952
Diseaseautism spectrum disorder (implicated_via_orthology)

SCN1A SCN2A CHD1 CHD6

9.33e-05152464DOID:0060041 (implicated_via_orthology)
Diseaseplatelet crit

SP4 AHI1 ZCWPW1 AFF3 NAV3 RRBP1 DENND2B MYLK2

1.00e-04952468EFO_0007985
Diseasewhite matter hyperintensity measurement

GON4L PDCD11 CHD6 ZNF831 DENND2B

1.06e-04302465EFO_0005665
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A

1.06e-0410462DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A

1.06e-0410462DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A

1.55e-0412462DOID:0060170 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

1.83e-0413462C0751122
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.46e-0415462EFO_0006519
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

2.81e-0416462C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

3.58e-0418462HP_0002373
DiseaseJoubert syndrome 1

CEP104 AHI1

4.90e-0421462C4551568
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A

5.38e-0422462DOID:2030 (implicated_via_orthology)
DiseaseIntellectual Disability

AHI1 SCN1A AFF3 NSD1 GON4L

6.41e-04447465C3714756
DiseaseFamilial aplasia of the vermis

CEP104 AHI1

1.01e-0330462C0431399
Diseaseage at menopause

BNC1 FNDC4 CHD6 NOBOX

1.25e-03302464EFO_0004704

Protein segments in the cluster

PeptideGeneStartEntry
SGHNNPKKGDAEPES

AFF3

341

P51826
PNGDASVEEDKQGKP

AHI1

111

Q8N157
EDSKGQPAFPNIGQN

BNC1

461

Q01954
SNKENSEQPQFPGKS

BRPF3

76

Q9ULD4
AGPEAGENQKQPEKN

CXCL16

181

Q9H2A7
GENQKQPEKNAGPTA

CXCL16

186

Q9H2A7
PTENGTENQPKFGSK

DENND2B

466

P78524
GAKASNPEPSFKANE

BCOR

616

Q6W2J9
SGKARPQPGSFNKQD

CCDC74A

181

Q96AQ1
PQPGSFNKQDSKADV

CCDC74A

186

Q96AQ1
SGKARPQPGSFNKQD

CCDC74B

181

Q96LY2
PQPGSFNKQDSKADV

CCDC74B

186

Q96LY2
GDPNAGFEKNKEPGE

CHD1

301

O14646
NLDAPEDKDSPFGNG

NSD1

21

Q96L73
NGKESKDNPAAPGPA

NOBOX

366

O60393
HNKEPKEKGSPGQND

TRIT1

446

Q9H3H1
AFKSQNATPKGPNAA

MAGED1

111

Q9Y5V3
DDKNSQEKGPQEAFP

FETUB

311

Q9UGM5
GGSEAPAPQNKDQKA

EBNA1BP2

81

Q99848
QPSKNDNGKPDSVGL

PCMTD1

221

Q96MG8
PKAEQGASGSQDPGK

MYLK2

111

Q9H1R3
KNKPPNYANGNEKDS

NAV3

281

Q8IVL0
DAGKDGNNPAKNRDA

HMGN4

61

O00479
APFKPLNDKNSNSGN

MRTFB

346

Q9ULH7
PASPEQELDQNKGKG

MKI67

306

P46013
KKASGQPAGPDNKEN

TK1

191

P04183
SGGEKPFQAQKQEPH

POP1

36

Q99575
PKNQDIQGGKAAPAE

CEP104

726

O60308
ATDNGLGKPDFPEAN

KCNA6

491

P17658
NFGKKNGSDPASGAP

LACTBL1

56

A8MY62
EVPGFGANFSDKPKQ

CHD6

2371

Q8TD26
GNYNGDPKDDFQKPN

FCGBP

1391

Q9Y6R7
DPKDDFQKPNGSQAG

FCGBP

1396

Q9Y6R7
CGNYNGDPKDDFQKP

FCGBP

2591

Q9Y6R7
GDPKDDFQKPNGSQA

FCGBP

2596

Q9Y6R7
NQDPADDLKAVGGKP

FCGBP

3416

Q9Y6R7
NGDPKDDFQKPNGSQ

FCGBP

3796

Q9Y6R7
DNDSNNNPKEKGKGP

FNDC4

196

Q9H6D8
KALEGNPENPEFNTG

IFIT1B

166

Q5T764
TQAKGPEGEQQPKAA

GON4L

2121

Q3T8J9
KPGYQPSGESDKENK

CEP350

686

Q5VT06
EGGKTSEPENNNKKP

SP4

21

Q02446
KQSEDGPKPSNQEGK

PRDM14

176

Q9GZV8
ENGPKPNSDLEAGKN

SCN1A

46

P35498
DSKNVFNPEAFKPGN

PDCD11

401

Q14690
PEQLGGQKEPSKNDH

STIL

1161

Q15468
FGNNPVDENGAKIPD

TIMM50

86

Q3ZCQ8
EGQGNSDSDQPGPKK

ZCWPW1

531

Q9H0M4
EGSPNQGKKADAAAN

RRBP1

581

Q9P2E9
DENGPKPNSDLEAGK

SCN2A

46

Q99250
QAKEATAGKNGPVEP

SNX19

171

Q92543
DSPGFKPASQQKAEA

TJP1

911

Q07157
KGCNDENNLPYKPDG

TOPAZ1

236

Q8N9V7
QKQDADPGEVPGGSK

ZNF831

856

Q5JPB2
EAKPDGEKDPDFNQS

USP48

896

Q86UV5
NPKFDEETANNKGGK

TMOD2

146

Q9NZR1
AYPNKGVGQANKPDE

ZNF638

1361

Q14966