Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	platelet-derived growth factor binding	COL3A1 COL5A1 COL6A1 PDGFRB	1.55e-07	12	86	4	GO:0048407
HumanPheno	Cigarette-paper scars	COL3A1 COL5A1 COL6A1	1.74e-05	10	28	3	HP:0001073
Domain	Amphiphysin	AMPH BIN2	6.72e-05	3	89	2	IPR003005
Pathway	REACTOME_NCAM1_INTERACTIONS	COL3A1 COL5A1 COL6A1	8.76e-05	20	62	3	MM15061
Pathway	REACTOME_SIGNALING_BY_PDGF	COL3A1 COL5A1 COL6A1 PDGFRB	1.13e-04	57	62	4	MM14713
Pathway	REACTOME_SIGNALING_BY_PDGF	COL3A1 COL5A1 COL6A1 PDGFRB	1.20e-04	58	62	4	M2049
Pubmed	Interactions between collagen gene variants and risk of anterior cruciate ligament rupture.	COL3A1 COL5A1 COL6A1	6.47e-08	4	89	3	25073002
Pubmed	Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB).	COL3A1 COL5A1 COL6A1	1.35e-06	9	89	3	8900172
Pubmed	Characterization of binding properties of the myelin-associated glycoprotein to extracellular matrix constituents.	COL3A1 COL5A1 COL6A1	1.92e-06	10	89	3	2446864
Pubmed	[IMAGE: molecular integration of the analysis of the human genome and its expression].	ZNF462 AMPH LRSAM1 CNKSR2	1.97e-06	35	89	4	7757816
Pubmed	Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice.	FGF23 ENPP1	6.48e-06	2	89	2	22359666
Pubmed	Human fibroblasts with mutations in COL5A1 and COL3A1 genes do not organize collagens and fibronectin in the extracellular matrix, down-regulate alpha2beta1 integrin, and recruit alphavbeta3 Instead of alpha5beta1 integrin.	COL3A1 COL5A1	6.48e-06	2	89	2	14970208
Pubmed	The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors.	COL3A1 COL6A1 PDGFRB	1.07e-05	17	89	3	22573622
Pubmed	Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.	COL3A1 COL6A1 NIBAN1 IGDCC3 DDX21 ENPEP	1.17e-05	196	89	6	19334288
Pubmed	Collagen Family Genes Associated with Risk of Recurrence after Radiation Therapy for Vestibular Schwannoma and Pan-Cancer Analysis.	COL3A1 COL5A1	1.94e-05	3	89	2	34691289
Pubmed	Distribution of collagen types I, III, and V in pregnant mouse endometrium.	COL3A1 COL5A1	1.94e-05	3	89	2	17453912
Pubmed	No association between COL3A1, COL6A1 or COL12A1 gene variants and range of motion.	COL3A1 COL6A1	1.94e-05	3	89	2	23013106
Pubmed	Follicular stimulating hormone enhances Notch 1 expression in SK-OV-3 ovarian cancer cells.	CGA NOTCH1	1.94e-05	3	89	2	20613903
Pubmed	Hypoxia and extra-cellular matrix gene expression in adipose tissue associates with reduced insulin sensitivity in black South African women.	COL5A1 COL6A1	1.94e-05	3	89	2	27628582
Pubmed	Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.	CDH2 NOTCH1	1.94e-05	3	89	2	36456828
Pubmed	Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.	SLFN11 TLR9	1.94e-05	3	89	2	38875319
Pubmed	TSGΔ154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation.	UBE2D1 LRSAM1	1.94e-05	3	89	2	26811492
Pubmed	Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.	PDGFRB NOTCH1	1.94e-05	3	89	2	18483410
Pubmed	N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability.	PDGFRB CDH2	1.94e-05	3	89	2	30463880
Pubmed	COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis.	COL3A1 COL6A1	1.94e-05	3	89	2	32999266
Pubmed	miR-29a-3p-dependent COL3A1 and COL5A1 expression reduction assists sulforaphane to inhibit gastric cancer progression.	COL3A1 COL5A1	1.94e-05	3	89	2	33819468
Pubmed	FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.	KIF1B BICD1	1.94e-05	3	89	2	31541015
Pubmed	Cell-cell adhesion through N-cadherin enhances VCAM-1 expression via PDGFRβ in a ligand-independent manner in mesenchymal stem cells.	PDGFRB CDH2	1.94e-05	3	89	2	24378362
Pubmed	Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.	COL3A1 COL5A1 COL6A1	3.15e-05	24	89	3	25344368
Pubmed	Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone.	COL3A1 COL5A1	3.87e-05	4	89	2	12874293
Pubmed	Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf.	RLF CNKSR2	3.87e-05	4	89	2	14597674
Pubmed	The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase.	UBE2D1 SHPRH	3.87e-05	4	89	2	31434570
Pubmed	LRSAM1-mediated ubiquitylation is disrupted in axonal Charcot-Marie-Tooth disease 2P.	UBE2D1 LRSAM1	3.87e-05	4	89	2	28335037
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	AMPH PDE1B CNKSR2 SYBU NSUN2 MARCKS	4.19e-05	246	89	6	15345747
Pubmed	SCAP knockout in SM22α-Cre mice induces defective angiogenesis in the placental labyrinth.	PDGFRB CDH2 NOTCH1	4.53e-05	27	89	3	33227706
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL3A1 THSD4 COL5A1 COL6A1 ADAMTSL4	4.76e-05	153	89	5	25037231
Pubmed	DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.	COL3A1 AMPH SYBU	6.26e-05	30	89	3	36460641
Pubmed	Notch inhibits apoptosis by direct interference with XIAP ubiquitination and degradation.	UBE2D1 NOTCH1	6.44e-05	5	89	2	17318174
Pubmed	Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch.	CDH2 NOTCH1	6.44e-05	5	89	2	21397841
Pubmed	The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline.	COL3A1 COL6A1	6.44e-05	5	89	2	11973338
Pubmed	Collagen and tenascin-C expression along the migration pathway of mouse primordial germ cells.	COL3A1 COL5A1	6.44e-05	5	89	2	14758483
Pubmed	Deficiency of Notch signaling in pericytes results in arteriovenous malformations.	PDGFRB NOTCH1	6.44e-05	5	89	2	33148887
Pubmed	Crim1 has cell-autonomous and paracrine roles during embryonic heart development.	COL3A1 COL5A1 PDGFRB	6.91e-05	31	89	3	26821812
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL3A1 COL5A1 COL6A1 ADAMTSL4	7.25e-05	86	89	4	28327460
Pubmed	A SOX17-PDGFB signaling axis regulates aortic root development.	PDGFRB CNOT3 NOTCH1	9.15e-05	34	89	3	35831318
Pubmed	ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.	COL3A1 COL5A1	9.65e-05	6	89	2	17029294
Pubmed	TLR4/NF-κB-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.	LRSAM1 DDX21	9.65e-05	6	89	2	25692136
Pubmed	A protective role for FGF-23 in local defence against disrupted arterial wall integrity?	FGF23 ENPP1	9.65e-05	6	89	2	23523568
Pubmed	Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.	TLR9 TNFRSF4	9.65e-05	6	89	2	23584070
Pubmed	Interaction of human thrombospondin with types I-V collagen: direct binding and electron microscopy.	COL3A1 COL5A1	9.65e-05	6	89	2	3571333
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	LRSAM1 APC2 BSDC1 CRELD2 CCDC88B ADAMTSL4 NOTCH1 BICD1	9.68e-05	560	89	8	21653829
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	COL3A1 PLXNC1 LRSAM1 ROR1 MARCKS NOTCH1 BICD1 PSD4	1.08e-04	569	89	8	30639242
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	COL3A1 COL5A1 COL6A1 CDH2	1.16e-04	97	89	4	27559042
Pubmed	Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin.	COL5A1 COL6A1	1.35e-04	7	89	2	9501082
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	TROAP PHRF1 CDH2 BTN2A1 MARCKS NOTCH1	1.42e-04	307	89	6	37499664
Pubmed	Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice.	CDH2 NOTCH1	1.79e-04	8	89	2	12001066
Pubmed	In vivo evidence for a bridging role of a collagen V subtype at the epidermis-dermis interface.	COL5A1 COL6A1	1.79e-04	8	89	2	22437311
Pubmed	Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance.	COL3A1 COL5A1	1.79e-04	8	89	2	18816857
Pubmed	Galectin-1 stimulates motility of human umbilical cord blood-derived mesenchymal stem cells by downregulation of smad2/3-dependent collagen 3/5 and upregulation of NF-κB-dependent fibronectin/laminin 5 expression.	COL3A1 COL5A1	1.79e-04	8	89	2	24503541
Pubmed	Mouse thioredoxin gene maps on chromosome 4, whereas its pseudogene maps on chromosome 1.	COL3A1 CGA	1.79e-04	8	89	2	8088797
Pubmed	Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.	CDH2 PLEKHO1	1.79e-04	8	89	2	22152476
Pubmed	Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve.	CDH2 NOTCH1 NOBOX	1.99e-04	44	89	3	37494420
Pubmed	Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.	COL3A1 COL5A1 COL6A1	1.99e-04	44	89	3	21308778
Pubmed	ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis.	COL3A1 COL5A1 COL6A1	2.13e-04	45	89	3	26446156
Pubmed	Adam10 mediates the choice between principal cells and intercalated cells in the kidney.	NOTCH1 SLC4A1	2.30e-04	9	89	2	24904084
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL3A1 COL5A1 COL6A1 ENPP1 UGGT1 CRELD2 ERGIC2 CDH2 BTN2A1 MARCKS NOTCH1	2.47e-04	1201	89	11	35696571
Pubmed	Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.	PDGFRB CDH2 NOTCH1	2.58e-04	48	89	3	28924218
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	COL5A1 COL6A1	2.88e-04	10	89	2	15345741
Pubmed	Interaction of Smads with collagen types I, III, and V.	COL3A1 COL5A1	2.88e-04	10	89	2	14559231
Pubmed	Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates.	CDH2 NOTCH1	2.88e-04	10	89	2	24715457
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	COL3A1 COL5A1 COL6A1	2.91e-04	50	89	3	23658023
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	RLF NIBAN1 IQCC ROR1 BRINP2 BSDC1 GON4L ADAMTSL4 RCAN3 TNFRSF4	3.07e-04	1031	89	10	16710414
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RLF RAD21L1 SPDEF TOGARAM1 DDX21 CCDC88B	3.38e-04	361	89	6	26167880
Pubmed	Calcium signaling induces partial EMT and renal fibrosis in a Wnt4mCherry knock-in mouse model.	COL3A1 PDGFRB NOTCH1	3.46e-04	53	89	3	38653356
Pubmed	A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development.	CDH2 NOTCH1	3.51e-04	11	89	2	27224017
Pubmed	Genetics of early mammalian folliculogenesis.	CGA NOBOX	3.51e-04	11	89	2	16416028
Pubmed	SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.	COL3A1 COL5A1	3.51e-04	11	89	2	2745554
Pubmed	Systematic Identification of Oncogenic EGFR Interaction Partners.	AMPH CNKSR2	4.20e-04	12	89	2	27956147
Pubmed	Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis.	UBE2D1 CDH2	4.20e-04	12	89	2	14960280
Pubmed	The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium.	KIF1B CDH2	4.20e-04	12	89	2	15834408
Pubmed	Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.	CDH2 ADAMTSL4	4.20e-04	12	89	2	26405179
Pubmed	Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.	CGA NOTCH1	4.20e-04	12	89	2	14732396
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	COL3A1 PDE1B SSH1 UGGT1 KIF1B RECQL5 BSDC1 CNKSR2 SLFN11 PLEKHO1 RCAN3	4.62e-04	1293	89	11	15342556
Pubmed	Desmoglein 2 regulates cardiogenesis by restricting hematopoiesis in the developing murine heart.	CDH2 NOTCH1	4.96e-04	13	89	2	34737300
Pubmed	Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis.	CDH2 NOTCH1	4.96e-04	13	89	2	27991863
Pubmed	EGR1 and EGR2 involvement in vertebrate tendon differentiation.	COL3A1 COL5A1	4.96e-04	13	89	2	21173153
Pubmed	SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.	CDH2 NOTCH1	4.96e-04	13	89	2	22522080
Pubmed	The Mohawk homeobox gene is a critical regulator of tendon differentiation.	COL3A1 COL6A1	4.96e-04	13	89	2	20498044
Pubmed	E3 ubiquitin ligase CHIP facilitates Toll-like receptor signaling by recruiting and polyubiquitinating Src and atypical PKC{zeta}.	UBE2D1 TLR9	5.78e-04	14	89	2	21911421
Pubmed	A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.	PHF11 TLR9	5.78e-04	14	89	2	20085599
Pubmed	Genetic linkage analysis of the Ak1, Col5a1, Epb7.2, Fpgs, Grp78, Pbx3, and Notch1 genes in the region of mouse chromosome 2 homologous to human chromosome 9q.	COL5A1 NOTCH1	5.78e-04	14	89	2	8088777
Pubmed	Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell.	COL3A1 NOTCH1	5.78e-04	14	89	2	37414855
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL3A1 FGF23 COL6A1	6.03e-04	64	89	3	22261194
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	PPP1R13B CNKSR2 SYBU BICD1	6.26e-04	151	89	4	17043677
Pubmed	Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli.	PDGFRB NOTCH1	6.65e-04	15	89	2	19087347
Pubmed	E3-independent monoubiquitination of ubiquitin-binding proteins.	UBE2D1 UBASH3A	6.65e-04	15	89	2	17588522
Pubmed	Trio controls the mature organization of neuronal clusters in the hindbrain.	CDH2 NOTCH1	6.65e-04	15	89	2	17898204
Pubmed	Endocardial cushion morphogenesis and coronary vessel development require chicken ovalbumin upstream promoter-transcription factor II.	PDGFRB NOTCH1	6.65e-04	15	89	2	22962329
Pubmed	Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.	PDGFRB NOTCH1	6.65e-04	15	89	2	37023750
Pubmed	The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.	CDH2 NOTCH1	7.59e-04	16	89	2	27641601
Pubmed	Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.	CDH2 NOTCH1	7.59e-04	16	89	2	17021047
Pubmed	Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance.	COL6A1 PDGFRB	7.59e-04	16	89	2	27546376
Pubmed	Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.	PDGFRB NOTCH1	7.59e-04	16	89	2	24353058
Pubmed	Developmental changes in extracellular matrix messenger RNAs in the mouse placenta during the second half of pregnancy: possible factors involved in the regulation of placental extracellular matrix expression.	COL3A1 COL5A1	7.59e-04	16	89	2	17881772
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	IQCC LRSAM1 KIF1B RECQL5 PPP1R13B SLFN11 CNOT3	7.94e-04	588	89	7	38580884
Pubmed	Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease.	COL6A1 UGGT1 NOTCH1	8.50e-04	72	89	3	19723774
Cytoband	8q23.2	KCNV1 SYBU	1.03e-04	8	89	2	8q23.2
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHO2 KIF1B DGKH CNKSR2 PLEKHO1 PSD4	7.35e-05	206	62	6	682
GeneFamily	ADAMTS like	THSD4 ADAMTSL4	2.40e-04	7	62	2	947
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	PDGFRB PLXNC1 TLR9 CDH2 ENPEP SLC4A1 TNFRSF4	3.88e-04	394	62	7	471
GeneFamily	Collagens	COL3A1 COL5A1 COL6A1	5.25e-04	46	62	3	490
GeneFamily	N-BAR domain containing	AMPH BIN2	7.47e-04	12	62	2	1289
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6	2.79e-03	23	62	2	662
GeneFamily	Sterile alpha motif domain containing	LRSAM1 DGKH CNKSR2	3.43e-03	88	62	3	760
GeneFamily	PHD finger proteins	PHF11 PHRF1 SHPRH	3.65e-03	90	62	3	88
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	PDGFRB ROR1	8.30e-03	40	62	2	321
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	NIBAN1 PDE1B ZNF335 KIF1B DGKH SLFN11 BICD1	4.43e-06	198	87	7	M6511
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL3A1 COL5A1 COL6A1 CDH2	5.48e-06	35	87	4	M11788
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	COL3A1 COL5A1 COL6A1 CDH2	6.15e-06	36	87	4	MM1212
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_MID_AIRWAY_PROGENITOR_CELL	THSD4 NIBAN1 CDH2	1.92e-05	16	87	3	M45702
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	COL3A1 COL5A1 COL6A1 TFEC PDGFRB PLXNC1 ROR1 ENPEP	2.27e-05	352	87	8	M17471
Coexpression	ONDER_CDH1_TARGETS_2_UP	COL3A1 COL5A1 COL6A1 ENPP1 ROR1 CDH2 MARCKS	2.41e-05	257	87	7	M13867
Coexpression	CUI_DEVELOPING_HEART_COMPACT_VENTRICULAR_CARDIOMYOCYTE	COL3A1 COL5A1 COL6A1 NIBAN1	6.57e-05	65	87	4	M39309
Coexpression	DURAND_STROMA_S_UP	COL3A1 NIBAN1 PDE1B PDGFRB PPP1R13B SLFN11 MARCKS	6.97e-05	304	87	7	MM1083
Coexpression	JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	COL3A1 COL6A1 PDGFRB CDH2	7.84e-05	68	87	4	M1406
Coexpression	TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP	COL3A1 COL5A1 PLXNC1 ENPEP	8.30e-05	69	87	4	M10165
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_PROXIMAL_SECRETORY_PROGENITORS_CELL	NIBAN1 BRINP2 SPDEF DGKH CDH2	8.86e-05	135	87	5	M45710
Coexpression	JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	COL3A1 COL6A1 PDGFRB CDH2	1.15e-04	75	87	4	MM1143
Coexpression	LANG_MYB_FAMILY_TARGETS	TFEC NSUN2 PSD4	1.21e-04	29	87	3	M1128
Coexpression	LANG_MYB_FAMILY_TARGETS	TFEC NSUN2 PSD4	1.21e-04	29	87	3	MM493
Coexpression	NABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS	COL3A1 COL5A1 COL6A1	1.21e-04	29	87	3	MM17055
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL5A1 COL6A1 ROR1 ADAMTSL4 ENPEP ABCA9 MARCKS	6.11e-09	197	89	8	2744cc94883c5d0424677cf5093bbab622933e9b
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 COL5A1 COL6A1 NIBAN1 ADAMTSL4 ENPEP ABCA9 MARCKS	6.61e-09	199	89	8	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	COL3A1 COL5A1 COL6A1 PDGFRB RAD21L1 CNKSR2 ABCA9	7.34e-08	179	89	7	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 AMPH NIBAN1 PDGFRB SYTL2 POPDC2 GLIS1	9.54e-08	186	89	7	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL3A1 COL5A1 COL6A1 CLIP3 AMPH IGDCC3 SYBU	1.14e-07	191	89	7	44b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 COL5A1 COL6A1 CLIP3 NIBAN1 PDGFRB ENPP1	1.46e-07	198	89	7	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ENPEP ABCA9	1.51e-07	199	89	7	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A1 ENPP1 ROR1 POPDC2 ABCA9	2.06e-07	126	89	6	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A1 ENPP1 ROR1 POPDC2 ABCA9	2.06e-07	126	89	6	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A1 ENPP1 ROR1 POPDC2 ABCA9	2.06e-07	126	89	6	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A1 ENPP1 ROR1 POPDC2 ABCA9	2.06e-07	126	89	6	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	COL3A1 COL6A1 ENPP1 ROR1 POPDC2 ABCA9	2.06e-07	126	89	6	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL5A1 COL6A1 ENPP1 ROR1 ABCA9	6.45e-07	153	89	6	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL5A1 COL6A1 ENPP1 ROR1 ABCA9	6.45e-07	153	89	6	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL3A1 COL5A1 COL6A1 ENPP1 ROR1 ABCA9	6.45e-07	153	89	6	2513edfae62a44e51d3556675a096723194c966c
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL3A1 COL5A1 FGF23 COL6A1 IGDCC3 ABCA9	7.51e-07	157	89	6	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NIBAN1 ADRA2B DPY19L2 PDGFRB SYTL2 ENPEP	1.19e-06	170	89	6	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH NIBAN1 PDGFRB PLXNC1 DGKH CDH2	1.19e-06	170	89	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 AMPH NIBAN1 POPDC2 CDH2 GLIS1	1.24e-06	171	89	6	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 UGGT1 APC2 SLFN11 ATG2A ADAMTSL4	1.24e-06	171	89	6	2b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NIBAN1 UGGT1 APC2 SLFN11 ATG2A ADAMTSL4	1.24e-06	171	89	6	dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLIP3 PDGFRB TROAP SAPCD2 CDH2 SLC4A1	1.41e-06	175	89	6	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ABCA9	1.51e-06	177	89	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 BRINP2 ADAMTSL4 ENPEP ABCA9 MARCKS	1.51e-06	177	89	6	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ABCA9	1.51e-06	177	89	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AMPH NIBAN1 DPY19L2 PDGFRB SYTL2 ENPEP	1.56e-06	178	89	6	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 CDH2	1.66e-06	180	89	6	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 CDH2	1.66e-06	180	89	6	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 ROR1	1.66e-06	180	89	6	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB CDH2	1.72e-06	181	89	6	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	COL3A1 COL5A1 PDGFRB FAM178B ENPEP NACAD	1.72e-06	181	89	6	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB CDH2	1.72e-06	181	89	6	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 CDH2	1.83e-06	183	89	6	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB CDH2	1.83e-06	183	89	6	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 CDH2	1.83e-06	183	89	6	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 CDH2	1.83e-06	183	89	6	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	1.95e-06	185	89	6	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	1.95e-06	185	89	6	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	1.95e-06	185	89	6	a94694e226856bc5b168464f52d76004145717a5
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THSD4 NIBAN1 DPY19L2 ROR1 POPDC2 CDH2	1.95e-06	185	89	6	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 CLIP3 ADRA2B PDGFRB	1.95e-06	185	89	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 CLIP3 ADRA2B PDGFRB	1.95e-06	185	89	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 CLIP3 ADRA2B PDGFRB	1.95e-06	185	89	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.01e-06	186	89	6	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.08e-06	187	89	6	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.08e-06	187	89	6	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.08e-06	187	89	6	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.14e-06	188	89	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	COL3A1 COL5A1 COL6A1 PDGFRB ENPP1 GLIS1	2.14e-06	188	89	6	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.21e-06	189	89	6	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB IGDCC3 ENPEP	2.21e-06	189	89	6	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB IGDCC3 ENPEP	2.21e-06	189	89	6	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	NIBAN1 PDE1B PLEKHO2 SLFN11 CCDC88B ADAMTSL4	2.21e-06	189	89	6	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 PDGFRB IGDCC3 ENPEP	2.21e-06	189	89	6	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AMPH NIBAN1 PDGFRB SYTL2 DGKH ENPEP	2.28e-06	190	89	6	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.28e-06	190	89	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ENPP1 ABCA9	2.35e-06	191	89	6	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.35e-06	191	89	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 NIBAN1 PDGFRB SYTL2 RAD21L1 CDH2	2.35e-06	191	89	6	9431ffd6b758f756609d9057de2023596e22b5d4
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.35e-06	191	89	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ROR1 ABCA9	2.35e-06	191	89	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ABCA9	2.35e-06	191	89	6	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ENPP1 ABCA9	2.35e-06	191	89	6	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ROR1 ABCA9	2.35e-06	191	89	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ENPP1 ABCA9	2.42e-06	192	89	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB CNKSR2 ABCA9	2.42e-06	192	89	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.42e-06	192	89	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	P28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 THSD4 NIBAN1 PDE1B PDGFRB CDH2	2.42e-06	192	89	6	87c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ABCA9	2.42e-06	192	89	6	859a32c9e4ed6961897b2ccaecde73a599471df9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ABCA9	2.42e-06	192	89	6	89e1da82fa2069dac7adb9cba3e8b6c0179e0dc5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 THSD4 COL5A1 PDGFRB ENPP1 ABCA9	2.42e-06	192	89	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 NIBAN1 DPY19L2 ROR1 POPDC2 CDH2	2.49e-06	193	89	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ROR1	2.49e-06	193	89	6	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.49e-06	193	89	6	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.57e-06	194	89	6	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 THSD4 COL5A1 COL6A1 PLEKHO2 CDH2	2.57e-06	194	89	6	ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.57e-06	194	89	6	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL3A1 COL5A1 COL6A1 ENPEP ABCA9 MARCKS	2.57e-06	194	89	6	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.57e-06	194	89	6	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 MARCKS	2.57e-06	194	89	6	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	THSD4 NIBAN1 DPY19L2 ROR1 PPP1R13B CDH2	2.57e-06	194	89	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	P15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL3A1 COL5A1 COL6A1 CLIP3 PDGFRB ENPP1	2.57e-06	194	89	6	5f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	COL3A1 COL5A1 COL6A1 PDGFRB PLXNC1 ENPEP	2.57e-06	194	89	6	55b97095a7a17a312c616703d291738a0f806339
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 COL5A1 COL6A1 ADRA2B PDGFRB ADAMTSL4	2.57e-06	194	89	6	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 NIBAN1 DPY19L2 ROR1 POPDC2 CDH2	2.64e-06	195	89	6	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 THSD4 COL5A1 COL6A1 PLEKHO2 CDH2	2.64e-06	195	89	6	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 MARCKS	2.64e-06	195	89	6	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.64e-06	195	89	6	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.64e-06	195	89	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.64e-06	195	89	6	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 ADAMTSL4	2.72e-06	196	89	6	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 MARCKS	2.72e-06	196	89	6	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	lymphoid-T_cell-Regulatory_T_cell\|World / Lineage, cell class and subclass	ZNF462 NIBAN1 ENPP1 BIN2 ATG2A TNFRSF4	2.72e-06	196	89	6	42a4d706382be33d552ece1d0598d073857a8d4e
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 COL5A1 CLIP3 PDGFRB CDH2 MARCKS	2.72e-06	196	89	6	acbb493dbb49a33f20cf11106363f7ed51209706
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYTL2 SHPRH PPP1R13B PDZD8 BIN2 PSD4	2.72e-06	196	89	6	c57a95f8b4d8d6334f269d3c16246684f4222a3e
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL3A1 COL5A1 COL6A1 NIBAN1 PDGFRB CNKSR2	2.72e-06	196	89	6	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 MARCKS	2.72e-06	196	89	6	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	PND10-Mesenchymal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL3A1 COL5A1 COL6A1 NIBAN1 PDGFRB ENPEP	2.72e-06	196	89	6	ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL3A1 COL5A1 COL6A1 PDGFRB ENPEP ABCA9	2.72e-06	196	89	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	COL3A1 COL5A1 COL6A1 PDGFRB ROR1 ADAMTSL4	2.72e-06	196	89	6	54aefcebf13704f51de84379e2e22ec0734b9461
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	COL5A1 RECQL5 GON4L CNOT3 RCAN3 BICD1 PSD4	1.15e-05	197	88	7	6012_DN
Drug	Sotalol hydrochloride [959-24-0]; Down 200; 13uM; PC3; HT_HG-U133A	THSD4 COL6A1 RECQL5 SYTL2 GON4L ENPEP CNOT3	1.15e-05	197	88	7	4079_DN
Drug	Milrinone [78415-72-2]; Up 200; 19uM; MCF7; HT_HG-U133A	FGF23 RECQL5 BSDC1 ENPEP BTN2A1 RCAN3 PSD4	1.18e-05	198	88	7	7210_UP
Drug	Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	FGF23 RECQL5 BRINP2 GON4L PLEKHO1 RCAN3 PSD4	1.22e-05	199	88	7	5458_DN
Disease	centronuclear myopathy 2 (implicated_via_orthology)	AMPH BIN2	2.57e-05	3	87	2	DOID:0111220 (implicated_via_orthology)
Disease	Intellectual Disability	ZNF462 ADRA2B PDGFRB ZNF335 APC2 GON4L NSUN2 CDH2	5.35e-05	447	87	8	C3714756
Disease	Rickets	FGF23 ENPP1	8.54e-05	5	87	2	cv:C0035579
Disease	Hypophosphatemic rickets	FGF23 ENPP1	8.54e-05	5	87	2	cv:C1704375
Disease	Hereditary hypophosphatemic rickets	FGF23 ENPP1	8.54e-05	5	87	2	cv:CN296404
Disease	Abnormality of the eye	APC2 CDH2	1.79e-04	7	87	2	C4316870
Disease	Ehlers-Danlos syndrome	COL3A1 COL5A1	2.38e-04	8	87	2	cv:C0013720
Disease	Leydig cell tumor (is_marker_for)	PDGFRB CGA	2.38e-04	8	87	2	DOID:2696 (is_marker_for)
Disease	Calcinosis	FGF23 PDGFRB NOTCH1	2.62e-04	42	87	3	C0006663
Disease	Microcalcification	FGF23 PDGFRB NOTCH1	2.62e-04	42	87	3	C0521174
Disease	Tumoral calcinosis	FGF23 PDGFRB NOTCH1	2.62e-04	42	87	3	C0263628
Disease	Ehlers-Danlos syndrome (is_implicated_in)	COL3A1 COL5A1	3.05e-04	9	87	2	DOID:13359 (is_implicated_in)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL3A1 COL5A1 NOTCH1	5.21e-04	53	87	3	C4707243
Disease	vascular endothelial growth factor measurement	ZNF462 ROR1 DGKH	6.13e-04	56	87	3	EFO_0004762
Disease	Global developmental delay	ZNF462 ZNF335 APC2 CDH2	6.57e-04	133	87	4	C0557874
Disease	juvenile dermatomyositis	ADRA2B SYBU	1.58e-03	20	87	2	EFO_0000557
Disease	cardiovascular system disease (is_implicated_in)	ENPP1 TLR9	1.74e-03	21	87	2	DOID:1287 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPDPVPQLSDCEAAF	ACCSL	116	Q4AC99
SPVAPEDIDLTPQEC	CYP2B6	461	P20813
DEVSEQECASGPPQP	ADAMTSL4	816	Q6UY14
QDCPTVSPDTALPEE	BICD1	941	Q96G01
LEASAECPQAPDSDP	CCDC88B	541	A6NC98
ECPQAPDSDPQEAES	CCDC88B	546	A6NC98
PQSPCEENLVTSVEP	BSDC1	256	Q9NW68
DCSLVLPPTDAPSEQ	SLC4A1	316	P02730
NETDSDPTPNDCFEP	ABCA9	456	Q8IUA7
LPPREDDSSQSPNAC	ERGIC2	156	Q96RQ1
EEEECEPQAVPVSPA	ADRA2B	306	P18089
SEEDEPLPACNGPAQ	BIN2	331	Q9UBW5
LPAEPAPSSDANDNE	PPP1R13B	781	Q96KQ4
CDEAVRDPSQAPPVD	ATG2A	201	Q2TAZ0
ICNLAESEQAPPTEP	AMPH	421	P49418
PPSPANCTTENSEDD	CNOT3	271	O75175
NEPPNDCSTDIESPS	CPXCR1	21	Q8N123
EEIEDQSPPCPRLSQ	NBPF4	406	Q96M43
PPTAALNEPQTFDCA	RCAN3	226	Q9UKA8
EPPNSLAVEPDNSEC	RAD21L1	241	Q9H4I0
ACERDQSQPSAPLED	IQCC	216	Q4KMZ1
PHAQDTQSEELPPSC	NOBOX	121	O60393
YEPDSANPDALQCPI	NSUN2	661	Q08J23
NVDDCNPPVDPVSRS	NOTCH1	1221	P46531
QDPAAPAPCEETQLS	IGDCC3	736	Q8IVU1
PSAPPAELEVQASEC	LRSAM1	661	Q6UWE0
PEANSRASSPCPEFE	KIF1B	1651	O60333
SPLELCDDANPVDNE	KCNV1	86	Q6PIU1
PEPETASRCNPAASD	PLXNC1	186	O60486
CEEEAPPSPAEDEHN	PDE1B	516	Q01064
LPSADAPNQAEPDVL	PDZD8	601	Q8NEN9
QAPPVLEVAAECEPD	PHRF1	1241	Q9P1Y6
VEEPCESINEPQCPA	ENPP1	191	P22413
PAQDQDICPASEDES	ENPEP	71	Q07075
EDPSNAANPPLCSVL	DPY19L2	721	Q6NUT2
DPTVHPCEPANQSSD	DGKH	641	Q86XP1
PDVQDCPECTLQENP	CGA	26	P01215
LVPAPAPAQEDDSCT	APC2	1376	O95996
DEPETPRAVAFQDCP	COL6A1	21	P12109
PEEGEPATQCQDPAA	GAGE12B;	41	A1L429
PEEGEPATQCQDPAA	GAGE12H	41	A6NDE8
PAPASCSQELPSAED	FGF23	201	Q9GZV9
AVPCAPENENPAFAT	C3orf62	81	Q6ZUJ4
PEEEECVAEPRPNFN	GON4L	611	Q3T8J9
SPDCDTAVPDTPQSQ	COL5A1	241	P20908
SVPDNPERFDSQPCV	BTN2A1	361	Q7KYR7
AAPSQEAQPECSPEA	MARCKS	311	P29966
ICDDQELDCPNPEIP	COL3A1	66	P02461
ASCPTALPQQPSEDV	GLIS1	576	Q8NBF1
DPNDPACQEILFDPQ	CLIP3	61	Q96DZ5
HPEPDCNPSEAASEE	DDX21	156	Q9NR30
VDECAAEPPPCSAAQ	CRELD2	231	Q6UXH1
LPQEAETCETPDPNS	CDH2	606	P19022
STISCDSPLEPQDEP	PDGFRB	1056	P09619
PPNDLLQDLEESCNG	RTL1	91	A6NKG5
PADELSHCVEPEPSQ	SYTL2	461	Q9HCH5
EEIEDQSPPCPRLSQ	NBPF6	406	Q5VWK0
PAEDAACLQSPQPED	TDRD12	1131	Q587J7
PPCQEQQPKASAELD	FAM178B	576	Q8IXR5
PCQEQTRATDPPEST	PSD4	86	Q8NDX1
NEPIIISDDDEQPCP	SHPRH	31	Q149N8
DPADPNSDPADLIFQ	SLFN11	181	Q7Z7L1
QEEDPSPEEPTSCAE	PLEKHO1	191	Q53GL0
ERCEDPNAPAICTQP	SSH1	666	Q8WYL5
PTFPECNCPDADIQA	BRINP2	301	Q9C0B6
PVSACDPQDDVQPPE	CNKSR2	861	Q8WXI2
SCSAQAEPPEPNEYD	RECQL5	626	O94762
NCEDLPQPESPEAAN	ROR1	281	Q01973
DQPIDFSEDARPSPC	MRPL38	276	Q96DV4
SEVSEREAQPPCPEA	NIBAN1	766	Q9BZQ8
EPKPCSDTNSDSPDE	RLF	1011	Q13129
EAAPCPAEPERSQSA	SAPCD2	166	Q86UD0
APVDTPSSEDFRPNC	TLR9	456	Q9NR96
QDPCPSSLASPDESE	SYBU	511	Q9NX95
PPEEPEQCPVIDSQA	SPDEF	86	O95238
ESSRQEQLEVPEPCP	TROAP	601	Q12815
DEEVCEPAVSPPQAT	POPDC2	286	Q9HBU9
SGLVECEDQDPLNPD	PHF11	76	Q9UIL8
CEDRDPPATQPQETQ	TNFRSF4	166	P43489
PPCQVPEESDQALDL	ZBTB42	176	B2RXF5
NSIPTPFPEQEAECP	ZNF462	1431	Q96JM2
PSPELCDQAIAFSDP	TFEC	271	O14948
EAPAAESAEPSQAPC	PLEKHO2	281	Q8TD55
PEDPLPCAVTLSNSN	TOGARAM1	331	Q9Y4F4
DPSECSFLEKPPSQQ	THSD4	891	Q6ZMP0
PEERESCNPQDCVPE	THSD4	956	Q6ZMP0
ENAAPSCPDEHDTLP	ZNF335	421	Q9H4Z2
QIAADEPPPEGCNSF	UGGT1	136	Q9NYU2
CDPNPDDPLVPDIAQ	UBE2D1	111	P51668
CNDPSLDDPIPQEYA	UBASH3A	61	P57075
AEAAEVTCPQEPLAP	ZNF628	421	Q5EBL2
PAPCLCQDPQEDSVE	NACAD	1246	O15069