Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin receptor activity	IGF1R INSR	6.54e-06	3	30	2	GO:0005009
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51E1 BMPR1B OR51D1 IGF1R KIR3DL2 OR51B6 MRGPRX1 GLP1R INSR OR4E1	1.69e-05	1353	30	10	GO:0004888
GeneOntologyMolecularFunction	insulin binding	IGF1R INSR	2.18e-05	5	30	2	GO:0043559
GeneOntologyMolecularFunction	peptide hormone binding	IGF1R GLP1R INSR	7.62e-05	55	30	3	GO:0017046
GeneOntologyMolecularFunction	insulin-like growth factor I binding	IGF1R INSR	1.68e-04	13	30	2	GO:0031994
GeneOntologyMolecularFunction	insulin receptor substrate binding	IGF1R INSR	2.26e-04	15	30	2	GO:0043560
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	BMPR1B IGF1R INSR	2.78e-04	85	30	3	GO:0019199
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGF1R INSR	3.67e-04	19	30	2	GO:0005520
GeneOntologyMolecularFunction	hormone binding	IGF1R GLP1R INSR	4.89e-04	103	30	3	GO:0042562
GeneOntologyMolecularFunction	protein-hormone receptor activity	IGF1R INSR	4.95e-04	22	30	2	GO:0016500
GeneOntologyMolecularFunction	growth factor binding	IGF1R RHBDF2 INSR	1.63e-03	156	30	3	GO:0019838
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51E1 OR51D1 OR51B6 MRGPRX1 GLP1R OR4E1	1.76e-03	884	30	6	GO:0004930
GeneOntologyMolecularFunction	protein transporter activity	IGF1R RHBDF2	1.81e-03	42	30	2	GO:0140318
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	IGF1R INSR	1.90e-03	43	30	2	GO:0043548
GeneOntologyMolecularFunction	olfactory receptor activity	OR51E1 OR51D1 OR51B6 OR4E1	3.76e-03	431	30	4	GO:0004984
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	IGF1R INSR	4.28e-03	65	30	2	GO:0004714
GeneOntologyCellularComponent	ATR-ATRIP complex	ATRIP ATR	1.73e-06	2	28	2	GO:0070310
GeneOntologyCellularComponent	insulin receptor complex	IGF1R INSR	1.04e-05	4	28	2	GO:0005899
GeneOntologyCellularComponent	plasma membrane protein complex	NOX4 BMPR1B IGF1R ITGAE ABCB8 INSR	5.10e-04	785	28	6	GO:0098797
GeneOntologyCellularComponent	plasma membrane signaling receptor complex	BMPR1B IGF1R ITGAE INSR	1.15e-03	350	28	4	GO:0098802
GeneOntologyCellularComponent	neuronal cell body membrane	MRGPRX1 INSR	1.51e-03	43	28	2	GO:0032809
GeneOntologyCellularComponent	cell body membrane	MRGPRX1 INSR	1.80e-03	47	28	2	GO:0044298
HumanPheno	Delayed skeletal maturation	BMPR1B IGF1R ATRIP ATR INSR	2.87e-05	352	7	5	HP:0002750
HumanPheno	Abnormality of skeletal maturation	BMPR1B IGF1R ATRIP ATR INSR	5.70e-05	405	7	5	HP:0000927
HumanPheno	Cone-shaped epiphysis	BMPR1B ATRIP ATR	1.34e-04	82	7	3	HP:0010579
HumanPheno	Abnormal toe morphology	KATNIP BMPR1B IGF1R ATRIP ATR RHBDF2	1.70e-04	893	7	6	HP:0001780
HumanPheno	Sandal gap	IGF1R ATRIP ATR	2.15e-04	96	7	3	HP:0001852
MousePheno	thin epidermis	IGF1R ATR RHBDF2	1.79e-05	33	22	3	MP:0001218
Domain	Tyr_kinase_insulin-like_rcpt	IGF1R INSR	6.98e-06	3	29	2	IPR016246
Domain	Furin-like	IGF1R INSR	4.87e-05	7	29	2	PF00757
Domain	Rcpt_L-dom	IGF1R INSR	4.87e-05	7	29	2	IPR000494
Domain	Furin-like_Cys-rich_dom	IGF1R INSR	4.87e-05	7	29	2	IPR006211
Domain	Recep_L_domain	IGF1R INSR	4.87e-05	7	29	2	PF01030
Domain	-	IGF1R INSR	4.87e-05	7	29	2	3.80.20.20
Domain	Tyr_kinase_rcpt_2_CS	IGF1R INSR	1.27e-04	11	29	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	IGF1R INSR	1.52e-04	12	29	2	PS00239
Domain	Furin_repeat	IGF1R INSR	3.51e-04	18	29	2	IPR006212
Domain	FU	IGF1R INSR	3.51e-04	18	29	2	SM00261
Domain	Pkinase_Tyr	BMPR1B IGF1R INSR	1.03e-03	129	29	3	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	BMPR1B IGF1R INSR	1.25e-03	138	29	3	IPR001245
Domain	HEAT	ECPAS ATR	2.51e-03	48	29	2	PF02985
Domain	VWA	ITGAE CLCA2	3.40e-03	56	29	2	PF00092
Domain	HEAT	ECPAS ATR	3.65e-03	58	29	2	IPR000357
Domain	Ank	ANKRD18A ANKRD19P ASB12	5.19e-03	228	29	3	PF00023
Domain	HEAT_REPEAT	ECPAS ATR	5.27e-03	70	29	2	PS50077
Domain	ANK	ANKRD18A ANKRD19P ASB12	6.77e-03	251	29	3	SM00248
Domain	ANK_REPEAT	ANKRD18A ANKRD19P ASB12	6.92e-03	253	29	3	PS50088
Domain	ANK_REP_REGION	ANKRD18A ANKRD19P ASB12	7.00e-03	254	29	3	PS50297
Domain	VWFA	ITGAE CLCA2	7.16e-03	82	29	2	PS50234
Domain	VWA	ITGAE CLCA2	7.50e-03	84	29	2	SM00327
Domain	Ankyrin_rpt	ANKRD18A ANKRD19P ASB12	7.62e-03	262	29	3	IPR002110
Domain	TyrKc	IGF1R INSR	8.20e-03	88	29	2	SM00219
Domain	Tyr_kinase_cat_dom	IGF1R INSR	8.20e-03	88	29	2	IPR020635
Domain	Kinase-like_dom	BMPR1B IGF1R ATR INSR	9.37e-03	542	29	4	IPR011009
Domain	PROTEIN_KINASE_TYR	IGF1R INSR	9.89e-03	97	29	2	PS00109
Domain	Tyr_kinase_AS	IGF1R INSR	9.89e-03	97	29	2	IPR008266
Domain	VWF_A	ITGAE CLCA2	1.03e-02	99	29	2	IPR002035
Domain	L_dom-like	KDM2A IGF1R INSR	1.40e-02	328	29	3	IPR032675
Pathway	WP_ATR_SIGNALING	ATRIP ATR	1.51e-04	11	24	2	M39507
Pathway	KEGG_MEDICUS_REFERENCE_ATR_SIGNALING	ATRIP ATR	1.81e-04	12	24	2	M47841
Pubmed	A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer.	IGF1R INSR	7.69e-07	2	31	2	21908557
Pubmed	A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.	IGF1R INSR	7.69e-07	2	31	2	19139090
Pubmed	Heterodimerization of glycosylated insulin-like growth factor-1 receptors and insulin receptors in cancer cells sensitive to anti-IGF1R antibody.	IGF1R INSR	7.69e-07	2	31	2	22438913
Pubmed	Apolipoprotein C3 and circulating mediators of preadipocyte proliferation in states of lipodystrophy.	IGF1R INSR	7.69e-07	2	31	2	35964946
Pubmed	Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.	IGF1R INSR	7.69e-07	2	31	2	12813019
Pubmed	Insulin/IGF-1 hybrid receptor expression on human platelets: consequences for the effect of insulin on platelet function.	IGF1R INSR	7.69e-07	2	31	2	19817984
Pubmed	Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.	IGF1R INSR	7.69e-07	2	31	2	19744489
Pubmed	Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.	IGF1R INSR	7.69e-07	2	31	2	28065828
Pubmed	Epigenetic DNA methylation in the promoters of the Igf1 receptor and insulin receptor genes in db/db mice.	IGF1R INSR	7.69e-07	2	31	2	21474992
Pubmed	Endothelial Cell Mediated Promotion of Ciliated Cell Differentiation of Human Airway Basal Cells via Insulin and Insulin-Like Growth Factor 1 Receptor Mediated Signaling.	IGF1R INSR	7.69e-07	2	31	2	28050756
Pubmed	Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior.	IGF1R INSR	7.69e-07	2	31	2	30765523
Pubmed	Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.	IGF1R INSR	7.69e-07	2	31	2	16642022
Pubmed	Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells.	IGF1R INSR	7.69e-07	2	31	2	24302626
Pubmed	IGF1R Expression in Ovarian Granulosa Cells Is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice.	IGF1R INSR	7.69e-07	2	31	2	28407051
Pubmed	Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.	IGF1R INSR	7.69e-07	2	31	2	26251471
Pubmed	Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis.	IGF1R INSR	7.69e-07	2	31	2	25981038
Pubmed	Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cells.	IGF1R INSR	7.69e-07	2	31	2	22879999
Pubmed	BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.	IGF1R INSR	7.69e-07	2	31	2	26438154
Pubmed	Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function.	IGF1R INSR	7.69e-07	2	31	2	38383709
Pubmed	Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.	IGF1R INSR	7.69e-07	2	31	2	23671263
Pubmed	Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.	IGF1R INSR	7.69e-07	2	31	2	36548088
Pubmed	Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis.	IGF1R INSR	7.69e-07	2	31	2	24809298
Pubmed	Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.	IGF1R INSR	7.69e-07	2	31	2	17189427
Pubmed	Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome.	ATRIP ATR	7.69e-07	2	31	2	23144622
Pubmed	Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities.	ATRIP ATR	7.69e-07	2	31	2	14729973
Pubmed	Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling.	IGF1R INSR	7.69e-07	2	31	2	31088290
Pubmed	Development of a Quantitative PCR Assay for Detection of Human Insulin-Like Growth Factor Receptor and Insulin Receptor Isoforms.	IGF1R INSR	7.69e-07	2	31	2	26862994
Pubmed	Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes--role of insulin and IGF-I receptors.	IGF1R INSR	7.69e-07	2	31	2	21524684
Pubmed	Human microvascular endothelial cells are sensitive to IGF-I but resistant to insulin at the receptor level.	IGF1R INSR	7.69e-07	2	31	2	18708119
Pubmed	A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.	IGF1R INSR	7.69e-07	2	31	2	21139139
Pubmed	The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.	IGF1R INSR	7.69e-07	2	31	2	25758790
Pubmed	Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes.	IGF1R INSR	7.69e-07	2	31	2	16644916
Pubmed	[Effects of insulin on expression of insulin receptor and insulin-like growth factor-1 receptor and proliferation in Reh cells].	IGF1R INSR	7.69e-07	2	31	2	22541124
Pubmed	The signaling potential of the receptors for insulin and insulin-like growth factor I (IGF-I) in 3T3-L1 adipocytes: comparison of glucose transport activity, induction of oncogene c-fos, glucose transporter mRNA, and DNA-synthesis.	IGF1R INSR	7.69e-07	2	31	2	1660482
Pubmed	Insulin and IGF1 receptors in human cardiac microvascular endothelial cells: metabolic, mitogenic and anti-inflammatory effects.	IGF1R INSR	7.69e-07	2	31	2	22825921
Pubmed	A functional assessment of insulin/insulin-like growth factor-I hybrid receptors.	IGF1R INSR	7.69e-07	2	31	2	7895674
Pubmed	Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice.	IGF1R INSR	7.69e-07	2	31	2	19851056
Pubmed	Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.	IGF1R INSR	7.69e-07	2	31	2	25246545
Pubmed	Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups.	IGF1R INSR	7.69e-07	2	31	2	28030849
Pubmed	Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds.	IGF1R INSR	7.69e-07	2	31	2	28468775
Pubmed	Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.	IGF1R INSR	7.69e-07	2	31	2	19835884
Pubmed	Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells.	IGF1R INSR	7.69e-07	2	31	2	27384680
Pubmed	Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.	IGF1R INSR	7.69e-07	2	31	2	35786404
Pubmed	Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.	IGF1R INSR	7.69e-07	2	31	2	27207510
Pubmed	Insulin-Mediated Signaling Facilitates Resistance to PDGFR Inhibition in Proneural hPDGFB-Driven Gliomas.	IGF1R INSR	7.69e-07	2	31	2	28138037
Pubmed	The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells.	IGF1R INSR	7.69e-07	2	31	2	20620597
Pubmed	Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.	IGF1R INSR	7.69e-07	2	31	2	27207537
Pubmed	Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells.	IGF1R INSR	7.69e-07	2	31	2	19406949
Pubmed	Mec1/ATR, the Program Manager of Nucleic Acids Inc.	ATRIP ATR	7.69e-07	2	31	2	28036033
Pubmed	Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis.	IGF1R INSR	7.69e-07	2	31	2	27905925
Pubmed	Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation.	IGF1R INSR	7.69e-07	2	31	2	30070361
Pubmed	Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.	IGF1R INSR	7.69e-07	2	31	2	25017244
Pubmed	Differential expression of IGF-I and insulin receptor isoforms in HPV positive and negative human cervical cancer cell lines.	IGF1R INSR	7.69e-07	2	31	2	18711691
Pubmed	Placental glycogen stores are increased in mice with H19 null mutations but not in those with insulin or IGF type 1 receptor mutations.	IGF1R INSR	7.69e-07	2	31	2	19524295
Pubmed	Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.	IGF1R INSR	7.69e-07	2	31	2	15063759
Pubmed	Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.	IGF1R INSR	7.69e-07	2	31	2	18650937
Pubmed	Genotype-Structure-Phenotype Correlations of Disease-Associated IGF1R Variants and Similarities to Those of INSR Variants.	IGF1R INSR	7.69e-07	2	31	2	34074726
Pubmed	Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes.	IGF1R INSR	7.69e-07	2	31	2	31562314
Pubmed	ATR-dependent phosphorylation of ATRIP in response to genotoxic stress.	ATRIP ATR	7.69e-07	2	31	2	15451423
Pubmed	ATRIP oligomerization is required for ATR-dependent checkpoint signaling.	ATRIP ATR	7.69e-07	2	31	2	16027118
Pubmed	Differential Expression of IR-A, IR-B and IGF-1R in Endometrial Physiology and Distinct Signature in Adenocarcinoma.	IGF1R INSR	7.69e-07	2	31	2	27088794
Pubmed	A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding.	IGF1R INSR	7.69e-07	2	31	2	30213860
Pubmed	Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells.	IGF1R INSR	7.69e-07	2	31	2	14722023
Pubmed	ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.	ATRIP ATR	7.69e-07	2	31	2	20861269
Pubmed	Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines.	IGF1R INSR	7.69e-07	2	31	2	22161861
Pubmed	IGF-I and insulin activate mitogen-activated protein kinase via the type 1 IGF receptor in mouse embryonic stem cells.	IGF1R INSR	7.69e-07	2	31	2	17641087
Pubmed	Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.	IGF1R INSR	7.69e-07	2	31	2	17416680
Pubmed	Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.	IGF1R INSR	7.69e-07	2	31	2	22692545
Pubmed	Deficiency in insulin-like growth factors signalling in mouse Leydig cells increase conversion of testosterone to estradiol because of feminization.	IGF1R INSR	7.69e-07	2	31	2	32975906
Pubmed	ATR and ATRIP: partners in checkpoint signaling.	ATRIP ATR	7.69e-07	2	31	2	11721054
Pubmed	Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity.	IGF1R INSR	7.69e-07	2	31	2	29040448
Pubmed	Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy.	IGF1R INSR	7.69e-07	2	31	2	24970814
Pubmed	Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.	IGF1R INSR	7.69e-07	2	31	2	26850678
Pubmed	High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy.	IGF1R INSR	7.69e-07	2	31	2	21177763
Pubmed	Amino-terminal domain of ATRIP contributes to intranuclear relocation of the ATR-ATRIP complex following DNA damage.	ATRIP ATR	7.69e-07	2	31	2	15527801
Pubmed	Regulation of Glucose Uptake and Enteroendocrine Function by the Intestinal Epithelial Insulin Receptor.	IGF1R INSR	7.69e-07	2	31	2	28096258
Pubmed	Expression and purification of functional insulin and insulin-like growth factor 1 holoreceptors from mammalian cells.	IGF1R INSR	7.69e-07	2	31	2	28830678
Pubmed	Insulin, insulin receptor and insulin-like growth factor-I receptor on the human ocular surface.	IGF1R INSR	7.69e-07	2	31	2	12613967
Pubmed	Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes.	IGF1R INSR	7.69e-07	2	31	2	18693051
Pubmed	Signalling through the insulin receptor and the insulin-like growth factor-I receptor.	IGF1R INSR	7.69e-07	2	31	2	7821728
Pubmed	hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.	ATRIP ATR	2.31e-06	3	31	2	21285353
Pubmed	TopBP1 activates ATR through ATRIP and a PIKK regulatory domain.	ATRIP ATR	2.31e-06	3	31	2	18519640
Pubmed	IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin.	IGF1R ATR	2.31e-06	3	31	2	27472395
Pubmed	Periovulatory insulin signaling is essential for ovulation, granulosa cell differentiation, and female fertility.	IGF1R INSR	2.31e-06	3	31	2	31908002
Pubmed	Insulin receptor-related receptor as an extracellular alkali sensor.	IGF1R INSR	2.31e-06	3	31	2	21641549
Pubmed	MAP3K4 promotes fetal and placental growth by controlling the receptor tyrosine kinases IGF1R/IR and Akt signaling pathway.	IGF1R INSR	2.31e-06	3	31	2	35921893
Pubmed	Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.	IGF1R INSR	2.31e-06	3	31	2	38816743
Pubmed	The Insulin Receptor and Insulin like Growth Factor Receptor 5' UTRs Support Translation Initiation Independently of EIF4G1.	IGF1R INSR	2.31e-06	3	31	2	37724583
Pubmed	Divergent roles of growth factors in the GnRH regulation of puberty in mice.	IGF1R INSR	2.31e-06	3	31	2	20628204
Pubmed	MicroRNA 322 Aggravates Dexamethasone-Induced Muscle Atrophy by Targeting IGF1R and INSR.	IGF1R INSR	2.31e-06	3	31	2	32046161
Pubmed	Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant.	IGF1R INSR	2.31e-06	3	31	2	16831875
Pubmed	Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification.	IGF1R INSR	2.31e-06	3	31	2	26475121
Pubmed	HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.	ATRIP ATR	2.31e-06	3	31	2	17384638
Pubmed	Differential impact of selective GH deficiency and endogenous GH excess on insulin-mediated actions in muscle and liver of male mice.	IGF1R INSR	2.31e-06	3	31	2	25269484
Pubmed	Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation.	ATRIP ATR	2.31e-06	3	31	2	18344416
Pubmed	Caveolin-1 increases glycolysis in pancreatic cancer cells and triggers cachectic states.	IGF1R INSR	2.31e-06	3	31	2	34320244
Pubmed	Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.	IGF1R INSR	2.31e-06	3	31	2	21681845
Pubmed	A novel protein activity mediates DNA binding of an ATR-ATRIP complex.	ATRIP ATR	2.31e-06	3	31	2	14724280
Pubmed	Insulin regulates neurovascular coupling through astrocytes.	IGF1R INSR	2.31e-06	3	31	2	35858325
Pubmed	Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.	IGF1R INSR	2.31e-06	3	31	2	27510031
Cytoband	11p15.4	OR51E1 OR51D1 OR51B6	3.35e-04	200	31	3	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51E1 OR51D1 OR51B6 MRGPRX1	5.45e-04	564	31	4	chr11p15
GeneFamily	Olfactory receptors, family 51	OR51E1 OR51D1 OR51B6	2.30e-05	44	23	3	164
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	BMPR1B IGF1R ITGAE KIR3DL2 INSR	1.17e-04	394	23	5	471
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	IGF1R INSR	1.17e-03	40	23	2	321
GeneFamily	Ankyrin repeat domain containing	ANKRD18A ASB12 ANKRD18B	3.44e-03	242	23	3	403
GeneFamily	Fibronectin type III domain containing	IGF1R INSR	1.74e-02	160	23	2	555
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	BMPR1B ATRIP CLCA2	1.62e-04	153	31	3	a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	1.84e-04	160	31	3	445cef1f2f3279672620664792d4eec54df71bdb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	2.05e-04	166	31	3	9e98e6070055bfc780becee52d77830e06b6d854
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	2.09e-04	167	31	3	31633899aae852873a4887e72c621474b0a51a33
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KATNIP ZNF610 TLE2	2.24e-04	171	31	3	6a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KATNIP ZNF610 TLE2	2.24e-04	171	31	3	9be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	BMPR1B CLCA2 ANKRD18B	2.24e-04	171	31	3	3965ced4be6db14265a90673502fceee425837ca
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	2.32e-04	173	31	3	3aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	2.32e-04	173	31	3	e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	BMPR1B CLCA2 INSR	2.36e-04	174	31	3	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|356C / Donor, Lineage, Cell class and subclass (all cells)	BMPR1B CLCA2 INSR	2.40e-04	175	31	3	4bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	BMPR1B CLCA2 INSR	2.40e-04	175	31	3	af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMPR1B CLCA2 INSR	2.48e-04	177	31	3	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BMPR1B CLCA2 INSR	2.48e-04	177	31	3	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BMPR1B CLCA2 ANKRD18B	2.52e-04	178	31	3	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	BMPR1B CLCA2 INSR	2.56e-04	179	31	3	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BMPR1B CLCA2 INSR	2.69e-04	182	31	3	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NOX4 OR51E1 TLE2	2.69e-04	182	31	3	997d37ca2af661c92a56add888762724dfccc890
ToppCell	Epithelial-lung_goblet_cell\|World / Lineage, Cell type, age group and donor	BMPR1B CLCA2 INSR	2.74e-04	183	31	3	940cbe298e9c53b5622af09264586ed823d3141f
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	BMPR1B IGF1R INSR	2.92e-04	187	31	3	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	BMPR1B CLCA2 ANKRD18B	2.92e-04	187	31	3	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	BMPR1B CLCA2 INSR	3.01e-04	189	31	3	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	BMPR1B IGF1R INSR	3.05e-04	190	31	3	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANKRD18A BMPR1B RASAL1	3.10e-04	191	31	3	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	NOX4 IGF1R INSR	3.15e-04	192	31	3	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.20e-04	193	31	3	21c397912f2dd1f4115cddbdc01a6a9beb1332cc
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 GLP1R	3.25e-04	194	31	3	4f28841c7f37884fc34c6689cd6976c6559d23f1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Myeloid-Microglia\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	TMEM144 RHBDF2 GLP1R	3.25e-04	194	31	3	459e836bcdb6742333684ac23d960efa5e99702f
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.30e-04	195	31	3	576142b4e75457c0973051bccc4163bd624496af
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.30e-04	195	31	3	ff9f6b38f41dc5660b746fe40ceaddfb2958acd3
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.30e-04	195	31	3	8f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.30e-04	195	31	3	2a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.30e-04	195	31	3	460e12044905370797fd9774e99c3aedaebfe343
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.34e-04	196	31	3	1ff4b41817556a6e573f0737819a5cc24a7ef821
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.34e-04	196	31	3	020110cd79453df9546fb20802fe38ecadd9fe74
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.34e-04	196	31	3	8e909c31733762646359fe78b645cbd60237459e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.40e-04	197	31	3	ff19e4c45715752a04541ad6a0cdf5454c9daaa2
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ITGAE RHBDF2 RASAL1	3.40e-04	197	31	3	78122e1fb80e0ac3084dd4f7c551996330a701df
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMPR1B IGF1R INSR	3.45e-04	198	31	3	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.45e-04	198	31	3	7896f9fb89822e8628fe0b90a489c4760c7b876c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMPR1B CLCA2 INSR	3.45e-04	198	31	3	778fee7020c82d11ff3984a8e482a23e5d58165f
ToppCell	distal-Epithelial-Mucous-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BMPR1B CLCA2 INSR	3.50e-04	199	31	3	35fb7bd35e53d8ca189fe8c7744211a5201081f6
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm\|Leuk-UTI / Disease, condition lineage and cell class	TRMT2B ANKRD18B RASAL1	3.50e-04	199	31	3	6a1d84f61e1efaab541910926d6911122372659f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BMPR1B CLCA2 ANKRD18B	3.50e-04	199	31	3	f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCell	distal-3-Epithelial-Mucous\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BMPR1B CLCA2 INSR	3.50e-04	199	31	3	64dc8a9b25cd52935bd3f956b5c65d2fd1bf4bf5
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Suprabasal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BMPR1B CLCA2 ANKRD18B	3.55e-04	200	31	3	924eacea513dde8e3bd805a335bc4285647b800d
Drug	Insulin Glargine	IGF1R INSR	1.68e-06	2	30	2	ctd:D000069036
Drug	Insulin Lispro	IGF1R INSR	1.68e-06	2	30	2	DB00046
Drug	Insulin Glargine	IGF1R INSR	1.68e-06	2	30	2	DB00047
Drug	Theobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A	TMEM144 TLE2 GLP1R ABCB8 INSR	4.99e-06	193	30	5	6613_DN
Drug	Mecasermin	IGF1R INSR	5.03e-06	3	30	2	DB01277
Drug	AC1L1GKK	IGF1R INSR	1.01e-05	4	30	2	CID000003725
Drug	PQ401	IGF1R INSR	1.67e-05	5	30	2	CID009549305
Drug	AC1L1CTI	IGF1R INSR	2.51e-05	6	30	2	CID000002057
Drug	pp175	IGF1R INSR	3.51e-05	7	30	2	CID000006543
Disease	gestational diabetes (biomarker_via_orthology)	IGF1R INSR	8.67e-06	5	28	2	DOID:11714 (biomarker_via_orthology)
Disease	Seckel syndrome (implicated_via_orthology)	ATRIP ATR	1.82e-05	7	28	2	DOID:0050569 (implicated_via_orthology)
Disease	alcohol dependence (implicated_via_orthology)	IGF1R INSR	3.11e-05	9	28	2	DOID:0050741 (implicated_via_orthology)
Disease	sleep disorder (implicated_via_orthology)	IGF1R INSR	4.75e-05	11	28	2	DOID:535 (implicated_via_orthology)
Disease	diabetic neuropathy (implicated_via_orthology)	IGF1R INSR	7.85e-05	14	28	2	DOID:9743 (implicated_via_orthology)
Disease	Congenital hernia of foramen of Morgagni	IGF1R INSR	1.47e-04	19	28	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	IGF1R INSR	1.47e-04	19	28	2	C0265700
Disease	Chronic myeloproliferative disorder	ATRIP ATR	1.47e-04	19	28	2	C1292778
Disease	prostate adenocarcinoma (is_implicated_in)	IGF1R INSR	1.63e-04	20	28	2	DOID:2526 (is_implicated_in)
Disease	Congenital diaphragmatic hernia	IGF1R INSR	1.80e-04	21	28	2	C0235833
Disease	Seckel syndrome	ATRIP ATR	1.98e-04	22	28	2	C0265202
Disease	Lewy Body Disease	IGF1R INSR	1.98e-04	22	28	2	C0752347
Disease	diabetes mellitus (implicated_via_orthology)	IGF1R INSR	2.78e-04	26	28	2	DOID:9351 (implicated_via_orthology)
Disease	glucose metabolism disease (implicated_via_orthology)	IGF1R INSR	3.23e-04	28	28	2	DOID:4194 (implicated_via_orthology)
Disease	Squamous cell carcinoma of lung	IGF1R ATR	4.23e-04	32	28	2	C0149782
Disease	high grade glioma (implicated_via_orthology)	IGF1R INSR	8.01e-04	44	28	2	DOID:3070 (implicated_via_orthology)
Disease	Gastric Adenocarcinoma	BMPR1B INSR	8.38e-04	45	28	2	C0278701
Disease	Alzheimer's disease (biomarker_via_orthology)	IGF1R INSR	1.39e-03	58	28	2	DOID:10652 (biomarker_via_orthology)
Disease	opioid dependence	NOX4 BMPR1B ABCB8	1.44e-03	237	28	3	EFO_0005611
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	IGF1R INSR	1.74e-03	65	28	2	DOID:0080208 (biomarker_via_orthology)
Disease	Alzheimer's disease (is_marker_for)	IGF1R ATR INSR	1.82e-03	257	28	3	DOID:10652 (is_marker_for)
Disease	Endometrial Carcinoma	IGF1R ATR	2.13e-03	72	28	2	C0476089
Disease	Lung diseases	IGF1R INSR	2.49e-03	78	28	2	C0024115
Disease	Parkinson Disease	IGF1R INSR	2.95e-03	85	28	2	C0030567
Disease	Acute Confusional Senile Dementia	IGF1R INSR	3.98e-03	99	28	2	C0546126
Disease	Presenile dementia	IGF1R INSR	3.98e-03	99	28	2	C0011265

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLHLACAHGRVQVVT	ANKRD18A	71	Q8IVF6
CAHGRVQVVTLLLHR	ANKRD18A	76	Q8IVF6
VLHLACAHGRVQVVT	ANKRD18B	71	A2A2Z9
GPIHHRALLISVTVC	BMPR1B	121	O00238
VLHLTCAHGRVEVVT	ANKRD19P	71	Q9H560
CHSIPVSHIRAVERV	RASAL1	611	O95294
CRHLHVLIGTSVVIF	KIR3DL2	336	P43630
IASAILLGFRHLHCT	GLP1R	161	P43220
TIDFTHPCHVALIRI	KATNIP	1061	O60303
ILSFILHTIVRGFIH	SLC43A2	451	Q8N370
LFTAVSHGHLDCVRV	ASB12	101	Q8WXK4
LRTLSLQFVHHICIT	ECPAS	371	Q5VYK3
EFNCHHVVRLLGVVS	IGF1R	1056	P08069
TVVRSHHGVLICIQV	ITGAE	96	P38570
VTVVCLTFIHRFGKH	OR51B6	251	Q9H340
FVAICHPLRHASVLT	OR51D1	136	Q8NGF3
VAICHPLRHATVLTL	OR51E1	126	Q8TCB6
FTCHHVVRLLGVVSK	INSR	1081	P06213
TICIFSGVHVAAHLV	NOX4	111	Q9NPH5
ISRICHSHDEVFVVL	ATR	2146	Q13535
VHLTHFELEGLRCLV	KDM2A	451	Q9Y2K7
ILQHLVCHSGAVVSL	ATRIP	481	Q8WXE1
VLVHCHAGVSRSVAI	DUSP12	111	Q9UNI6
IAHRLSTVRGAHCIV	ABCB8	666	Q9NUT2
RAIHTLVFVSCKLHG	TRMT2B	441	Q96GJ1
REVLFCHVHLVSIFL	MRGPRX1	246	Q96LB2
LSCLVAIGRLHSHVV	ARNTL	311	O00327
GLIGIICLIIVVTHH	CLCA2	911	Q9UQC9
AFRECSGLTTHLVIH	ZNF610	296	Q8N9Z0
AHLTVVTLFLGHCIF	OR4E1	246	P0C645
STVHHRIVGCSLAVI	TMEM144	181	Q7Z5S9
LFLHAGVVHCLVSVV	RHBDF2	661	Q6PJF5
LHTLAHGEVVCAVTI	TLE2	451	Q04725