Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	3.57e-08	44	44	5	GO:0048026
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	6.21e-08	49	44	5	GO:0050685
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	2.24e-07	63	44	5	GO:0033120
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	3.09e-07	129	44	6	GO:0048024
GeneOntologyBiologicalProcess	regulation of mRNA processing	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	1.02e-06	158	44	6	GO:0050684
GeneOntologyBiologicalProcess	regulation of RNA splicing	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	4.88e-06	207	44	6	GO:0043484
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	1.06e-04	358	44	6	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	1.06e-04	358	44	6	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	1.13e-04	362	44	6	GO:0000375
GeneOntologyBiologicalProcess	positive regulation of mRNA metabolic process	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	2.19e-04	259	44	5	GO:1903313
GeneOntologyBiologicalProcess	regulation of mRNA metabolic process	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	3.36e-04	443	44	6	GO:1903311
GeneOntologyBiologicalProcess	negative thymic T cell selection	AIRE GLI3	3.98e-04	14	44	2	GO:0045060
GeneOntologyBiologicalProcess	negative T cell selection	AIRE GLI3	4.59e-04	15	44	2	GO:0043383
GeneOntologyCellularComponent	spliceosomal complex	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F	7.34e-06	215	46	6	GO:0005681
GeneOntologyCellularComponent	male germ cell nucleus	RBMY1D RBMY1B AIRE RBMY1A1	3.82e-05	86	46	4	GO:0001673
GeneOntologyCellularComponent	germ cell nucleus	RBMY1D RBMY1B AIRE RBMY1A1	1.11e-04	113	46	4	GO:0043073
Domain	RBM1CTR	RBMY1D RBMY1B RBMY1A1 RBMY1F	1.39e-09	8	41	4	PF08081
Domain	RBM1CTR	RBMY1D RBMY1B RBMY1A1 RBMY1F	1.39e-09	8	41	4	IPR012604
Domain	RRM_1	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1F RAVER1	5.77e-06	208	41	6	PF00076
Domain	RRM	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1F RAVER1	7.35e-06	217	41	6	SM00360
Domain	RRM_dom	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1F RAVER1	9.51e-06	227	41	6	IPR000504
Domain	RRM	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1F RAVER1	1.02e-05	230	41	6	PS50102
Domain	Nucleotide-bd_a/b_plait	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1F RAVER1	1.97e-05	258	41	6	IPR012677
Domain	-	RBMY1D RBMY1B SRSF2 RBMY1F RAVER1	1.86e-04	244	41	5	3.30.70.330
Domain	Semaphorin	SEMA3G SEMA3E	8.71e-04	20	41	2	IPR027231
Domain	SEMA	SEMA3G SEMA3E	2.10e-03	31	41	2	PS51004
Domain	Sema	SEMA3G SEMA3E	2.10e-03	31	41	2	SM00630
Domain	Semap_dom	SEMA3G SEMA3E	2.10e-03	31	41	2	IPR001627
Domain	Sema	SEMA3G SEMA3E	2.10e-03	31	41	2	PF01403
Domain	PSI	SEMA3G SEMA3E	4.20e-03	44	41	2	IPR016201
Domain	PSI	SEMA3G SEMA3E	4.58e-03	46	41	2	SM00423
Domain	Growth_fac_rcpt_	NOTCH3 EPHA1 STAB1	4.83e-03	156	41	3	IPR009030
Domain	EGF_extracell	NOTCH3 STAB1	7.68e-03	60	41	2	IPR013111
Domain	EGF_2	NOTCH3 STAB1	7.68e-03	60	41	2	PF07974
Domain	F-box	KDM2B FBXL22	9.50e-03	67	41	2	PF00646
Domain	FBOX	KDM2B FBXL22	1.09e-02	72	41	2	PS50181
Pathway	KEGG_AXON_GUIDANCE	SEMA3G SRGAP1 EPHA1 SEMA3E	1.97e-04	129	32	4	M5539
Pathway	KEGG_MEDICUS_REFERENCE_P16_CELL_CYCLE_G1_S	CCND3 CDKN2A	2.22e-04	10	32	2	M47418
Pathway	PID_AR_PATHWAY	CCND3 CDKN2A ZNF318	3.50e-04	61	32	3	M58
Pathway	KEGG_MEDICUS_REFERENCE_MDM2_P21_CELL_CYCLE_G1_S_N00066	CCND3 CDKN2A	3.83e-04	13	32	2	M47416
Pubmed	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	6.78e-14	7	46	5	8269511
Pubmed	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.	RBMY1D RBMY1B RBMY1A1 RBMY1C RBMY1F	2.54e-12	12	46	5	9598316
Pubmed	RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.	RBMY1D RBMY1B RBMY1A1 RBMY1F	4.01e-11	6	46	4	15184870
Pubmed	Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.	RBMY1D RBMY1B RBMY1A1 RBMY1F	9.34e-11	7	46	4	8875892
Pubmed	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.	RBMY1B RBMY1A1 RBMY1C RBMY1F	1.90e-09	13	46	4	10749975
Pubmed	An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.	RBMY1D RBMY1B RBMY1A1	2.16e-08	5	46	3	8817321
Pubmed	Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.	RBMY1D RBMY1B RBMY1A1	2.16e-08	5	46	3	20016065
Pubmed	The role of human and mouse Y chromosome genes in male infertility.	RBMY1D RBMY1B RBMY1A1	2.16e-08	5	46	3	11097427
Pubmed	Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.	RBMY1D RBMY1B RBMY1A1	2.16e-08	5	46	3	19737860
Pubmed	The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.	RBMY1D RBMY1B RBMY1A1	4.32e-08	6	46	3	18239052
Pubmed	Identification of target messenger RNA substrates for mouse RBMY.	RBMY1D RBMY1B RBMY1A1	4.32e-08	6	46	3	18492746
Pubmed	Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.	RBMY1D RBMY1B RBMY1A1	4.32e-08	6	46	3	12356914
Pubmed	Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.	RBMY1D RBMY1B RBMY1A1	4.32e-08	6	46	3	9499427
Pubmed	Does Rbmy have a role in sperm development in mice?	RBMY1D RBMY1B RBMY1A1	4.32e-08	6	46	3	15051956
Pubmed	RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.	RBMY1D RBMY1B RBMY1A1	7.55e-08	7	46	3	17001072
Pubmed	The roles of RNA-binding proteins in spermatogenesis and male infertility.	RBMY1D RBMY1B RBMY1A1	7.55e-08	7	46	3	10377282
Pubmed	Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.	RBMY1D RBMY1B RBMY1A1	1.21e-07	8	46	3	7479793
Pubmed	Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.	RBMY1D RBMY1B RBMY1A1	2.58e-07	10	46	3	10601091
Pubmed	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.	RBMY1D RBMY1B RBMY1A1	2.58e-07	10	46	3	9384609
Pubmed	The role of Dby mRNA in early development of male mouse zygotes.	RBMY1D RBMY1B RBMY1A1	4.72e-07	12	46	3	20543856
Pubmed	GASZ promotes germ cell derivation from embryonic stem cells.	RBMY1D RBMY1B RBMY1A1	6.14e-07	13	46	3	23816659
Pubmed	Absence of mDazl produces a final block on germ cell development at meiosis.	RBMY1D RBMY1B RBMY1A1	7.80e-07	14	46	3	14611631
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	RBMY1D RBMY1B RBMY1A1	9.74e-07	15	46	3	14762062
Pubmed	Loss of maternal Trim28 causes male-predominant early embryonic lethality.	RBMY1D RBMY1B RBMY1A1	1.45e-06	17	46	3	28115466
Pubmed	Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis.	RBMY1B RBMY1A1	1.71e-06	2	46	2	32473614
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	RBMY1D RBMY1B RBMY1A1	1.74e-06	18	46	3	12023983
Pubmed	Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.	CDKN2A NOTCH3	5.13e-06	3	46	2	21118965
Pubmed	Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus.	CDKN2A KDM2B	5.13e-06	3	46	2	19202064
Pubmed	Cdk6-cyclin D3 activity in murine ES cells is resistant to inhibition by p16(INK4a).	CCND3 CDKN2A	5.13e-06	3	46	2	14724578
Pubmed	Histone demethylase KDM2B promotes triple negative breast cancer proliferation by suppressing p15INK4B, p16INK4A, and p57KIP2 transcription.	CDKN2A KDM2B	5.13e-06	3	46	2	30060056
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	RBMY1D RBMY1B RBMY1A1	5.51e-06	26	46	3	35920200
Pubmed	Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells.	SEMA3G SEMA3E	1.71e-05	5	46	2	18818766
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	LRFN1 SEMA3G EPHA1 SEMA3E	1.78e-05	117	46	4	17145500
Pubmed	p14ARF interacts with N-Myc and inhibits its transcriptional activity.	CDKN2A NOTCH3	2.56e-05	6	46	2	17289033
Pubmed	Growth suppression by p16ink4 requires functional retinoblastoma protein.	CCND3 CDKN2A	2.56e-05	6	46	2	7603984
Pubmed	Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells.	CCND3 CDKN2A	2.56e-05	6	46	2	10891505
Pubmed	A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.	CCND3 CDKN2A	3.58e-05	7	46	2	23948297
Pubmed	FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.	BARX1 GLI3	3.58e-05	7	46	2	19049965
Pubmed	Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.	CCND3 CDKN2A EPHA1	4.31e-05	51	46	3	19769959
Pubmed	Functional characterization of human PFTK1 as a cyclin-dependent kinase.	CCND3 CDKN2A	4.77e-05	8	46	2	17517622
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	RBMY1D RBMY1B RBMY1A1	5.41e-05	55	46	3	19468303
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	RBMY1D RBMY1B RBMY1A1	6.68e-05	59	46	3	11279525
Pubmed	Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women.	SRGAP1 SEMA3E	7.65e-05	10	46	2	25134534
Pubmed	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.	RBMY1A1 RBMY1C	7.65e-05	10	46	2	10332027
Pubmed	Primary cilia regulate Shh activity in the control of molar tooth number.	BARX1 GLI3	9.34e-05	11	46	2	19211681
Pubmed	Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.	CCND3 CDKN2A	1.12e-04	12	46	2	24876127
Pubmed	Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.	SEMA3G SEMA3E	1.12e-04	12	46	2	19812329
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	SEMA3G SEMA3E	1.12e-04	12	46	2	23991118
Pubmed	Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.	CCND3 CDKN2A	1.32e-04	13	46	2	18174243
Pubmed	Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.	SEMA3G SEMA3E	1.32e-04	13	46	2	27880905
Pubmed	Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohort.	CCND3 CDKN2A	1.32e-04	13	46	2	18507837
Pubmed	Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.	CCND3 CDKN2A	1.32e-04	13	46	2	17409409
Pubmed	Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.	CCND3 CDKN2A	1.32e-04	13	46	2	19258477
Pubmed	Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.	CCND3 CDKN2A	1.54e-04	14	46	2	12130539
Pubmed	Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.	CDKN2A KDM2B	1.54e-04	14	46	2	21220025
Pubmed	Effects of common germ-line genetic variation in cell cycle genes on ovarian cancer survival.	CCND3 CDKN2A	1.54e-04	14	46	2	18281541
Pubmed	Transcriptional repression of p27 is essential for murine embryonic development.	CCND3 CDKN2A	1.78e-04	15	46	2	27196371
Pubmed	The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.	CDKN2A KDM2B	1.78e-04	15	46	2	25463925
Pubmed	Expression of cell cycle-related proteins in developing and adult mouse hippocampus.	CCND3 CDKN2A	2.03e-04	16	46	2	15730892
Pubmed	Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation.	CCND3 CDKN2A	2.30e-04	17	46	2	17000767
Pubmed	Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation.	BARX1 GLI3	2.30e-04	17	46	2	25626636
Pubmed	Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the β-catenin pathway.	BARX1 GLI3	2.58e-04	18	46	2	24424161
Pubmed	Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition.	BARX1 GLI3	2.58e-04	18	46	2	9716414
Pubmed	Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.	RBMY1D RBMY1B RBMY1A1	2.75e-04	95	46	3	24029230
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CDK5RAP2 ZNF318 MCCC2 KIF26B ZNF316 ZNF646	2.82e-04	689	46	6	36543142
Pubmed	The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.	RBMY1D RBMY1B RBMY1A1 RBMY1F	2.92e-04	241	46	4	12815422
Pubmed	Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia.	GLI3 NOTCH3	3.54e-04	21	46	2	22935613
Pubmed	Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.	BARX1 GLI3	3.54e-04	21	46	2	32855417
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA3G SEMA3E	3.54e-04	21	46	2	36240771
Pubmed	Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium.	CDKN2A KDM2B	3.89e-04	22	46	2	26711500
Pubmed	Primary cilia in murine palatal rugae development.	BARX1 GLI3	4.25e-04	23	46	2	31226309
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	KDM2B IRF2BP2	4.64e-04	24	46	2	33722704
Pubmed	GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation.	GLI3 NOTCH3	4.64e-04	24	46	2	32497091
Pubmed	Sonic hedgehog signaling regulates Gli3 processing, mesenchymal proliferation, and differentiation during mouse lung organogenesis.	CCND3 GLI3	5.04e-04	25	46	2	15136151
Pubmed	Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression.	CCND3 CDKN2A	5.45e-04	26	46	2	23506836
Pubmed	Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.	GLI3 EPHA1	5.45e-04	26	46	2	35927240
Pubmed	Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development.	AIRE NOTCH3	5.45e-04	26	46	2	32467237
Pubmed	Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.	SEMA3G SEMA3E	6.33e-04	28	46	2	25993318
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM2B CDK5RAP2 SEMA3E STAB1 ZNF646	6.55e-04	529	46	5	14621295
Pubmed	Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.	CDKN2A CDK5RAP2	6.79e-04	29	46	2	22898775
Pubmed	Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.	CCND3 GLI3	6.79e-04	29	46	2	19474320
Pubmed	Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation.	CCND3 CDKN2A	6.79e-04	29	46	2	25556712
Pubmed	Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis.	CCND3 CDKN2A	6.79e-04	29	46	2	14522949
Pubmed	Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling.	CCND3 GLI3	7.27e-04	30	46	2	16368932
Pubmed	Self-assembling protein microarrays.	CCND3 CDKN2A	7.27e-04	30	46	2	15232106
Pubmed	Senescence is a developmental mechanism that contributes to embryonic growth and patterning.	CDKN2A GLI3	7.27e-04	30	46	2	24238961
Pubmed	Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.	CCND3 GLI3	7.27e-04	30	46	2	24073291
Pubmed	Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.	BARX1 GLI3	7.27e-04	30	46	2	26057579
Pubmed	pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.	GLI3 NOTCH3	7.27e-04	30	46	2	17257418
Pubmed	Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.	SEMA3G SEMA3E	7.77e-04	31	46	2	22076636
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	NOTCH3 STAB1	7.77e-04	31	46	2	31550482
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KDM2B IRF2BP2 ZNF318 RAVER1	1.05e-03	339	46	4	30415952
Pubmed	Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.	GLI3 NOTCH3	1.11e-03	37	46	2	26697723
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	RBMY1D RBMY1B SRSF2 RBMY1A1	1.14e-03	347	46	4	16033648
Pubmed	Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b.	CCND3 CDKN2A	1.23e-03	39	46	2	23341776
Pubmed	Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis.	CCND3 CDKN2A	1.23e-03	39	46	2	19738611
Cytoband	Yq11.223	RBMY1D RBMY1B RBMY1A1 RBMY1F	2.41e-06	93	46	4	Yq11.223
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	CACNA1A COL5A3 NMRK2 MED26 NOTCH3 RAVER1	1.39e-04	797	46	6	chr19p13
Cytoband	Ensembl 112 genes in cytogenetic band chrYq11	RBMY1D RBMY1B RBMY1A1 RBMY1F	2.69e-04	311	46	4	chrYq11
Cytoband	3p21.1	SEMA3G STAB1	8.24e-04	42	46	2	3p21.1
GeneFamily	RNA binding motif containing	RBMY1D RBMY1B SRSF2 RBMY1A1 RBMY1C RBMY1F RAVER1	7.48e-08	213	32	7	725
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3G SEMA3E	5.65e-04	20	32	2	736
GeneFamily	F-box and leucine rich repeat proteins	KDM2B FBXL22	6.24e-04	21	32	2	558
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_200	SEMA3G SRGAP1 SEMA3E	1.43e-05	23	44	3	gudmap_developingKidney_e15.5_Podocyte cells_200_k4
ToppCell	Biopsy_Other_PF-Epithelial-KRT5-/KRT17+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDKN2A BNIP5 KIF26B NOTCH3 EPHA1	1.56e-06	200	44	5	077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A AIRE COL5A3 SEMA3E	1.65e-05	155	44	4	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A COL5A3 ZNF318 ASTL	2.11e-05	165	44	4	e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A COL5A3 ZNF318 ASTL	2.11e-05	165	44	4	b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1A COL5A3 ZNF318 ASTL	2.11e-05	165	44	4	d8f8b088fd28a6b9dbd6b51bcaee42000e963321
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AIRE KDM2B SRGAP1 KCNH3	3.30e-05	185	44	4	48de4d9fad55077732bf64eca4919103ecbc1512
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A3 BNIP5 NPAP1 ZNF316	3.90e-05	193	44	4	df4afb4848eb9d7d8d39e5c612919663cbbb2514
ToppCell	Parenchymal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL5A3 BNIP5 NPAP1 ZNF316	3.90e-05	193	44	4	ab36d684bde8fe77d11a5188425135328052c58b
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL5A3 KIF26B GLI3 NOTCH3	3.98e-05	194	44	4	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL5A3 BARX1 GLI3 SEMA3E	4.48e-05	200	44	4	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL5A3 BARX1 GLI3 SEMA3E	4.48e-05	200	44	4	de1d193f773f4e2927baa6fc38d29754b015c6e6
Drug	HgCl	RBMY1D RBMY1B CDKN2A RBMY1A1	2.64e-06	49	45	4	CID000024182
Drug	thioglycolate	RBMY1D RBMY1B RBMY1A1 OPRD1	9.32e-06	67	45	4	CID000001133
Drug	hydantoin-5-propionic acid	RBMY1D RBMY1B RBMY1A1	9.36e-06	21	45	3	CID000000782
Drug	AZFd	RBMY1D RBMY1B RBMY1A1	1.24e-05	23	45	3	CID000196489
Disease	Adenocarcinoma Of Esophagus	CDKN2A BARX1	1.61e-04	14	40	2	C0279628
Disease	Carcinoma, Pancreatic Ductal	CDKN2A NOTCH3	4.85e-04	24	40	2	C0887833
Disease	age at first birth measurement	CACNA1A KCNH3 EZHIP	5.81e-04	120	40	3	EFO_0009101
Disease	myelodysplastic syndrome (is_implicated_in)	CDKN2A SRSF2	7.61e-04	30	40	2	DOID:0050908 (is_implicated_in)
Disease	acute lymphoblastic leukemia (is_marker_for)	CDKN2A KDM2B	9.78e-04	34	40	2	DOID:9952 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RPGRPSGRNHCSPSE	C2orf16	1916	Q68DN1
VPGPARSESPRACRH	CACNA1A	2371	O00555
RASGPACASPSRHGR	CACNA1A	2456	O00555
HPHCSFTPRPRRRGC	CCDC185	61	Q8N715
CLPHARASPRPSGAP	EPHA1	231	P21709
RPCPRSRGLLGPSHS	CCDC187	621	A0A096LP49
CEGTRHAPRAGPDPR	CCND3	6	P30281
HSHPTRARRCPGGLP	CDKN2A	91	Q8N726
CSPSGPRPRGRGSHA	ASTL	281	Q6HA08
RCHFPAGTSRPGTGL	AIRE	456	O43918
LRPGGAHPGTCSPSR	CDK5RAP2	1876	Q96SN8
RYGTSHGAPPARGPR	RBMY1A1	396	P0DJD3
RYGTSHGAPPARGPR	RBMY1B	396	A6NDE4
RYGTSHGAPPARGPR	RBMY1C	396	P0DJD4
RYGTSHGAPPARGPR	RBMY1D	396	P0C7P1
RYGTSHGAPPARGPR	RBMY1F	396	Q15415
HLRVSFCAPGPPGRS	RAVER1	291	Q8IY67
APHREGPCPRASGEG	KCNH3	911	Q9ULD8
PPVHAPRRCSDGGAH	GLI3	971	P10071
PCARASPAGPRAYHG	MCCC2	11	Q9HCC0
PAPCRPLRAHFLGGT	LRFN1	521	Q9P244
GVFRPCHVRPTGDPS	CELF2-AS1	121	Q8N7Q2
PPRRPHRCSSGHGSD	KIF26B	1856	Q2KJY2
RGCTAQPGPAFPHRA	EZHIP	236	Q86X51
RFGPPEGCADHRPHR	BARX1	11	Q9HBU1
PGSASALGYPRHCPR	FAM205A	1306	Q6ZU69
HGGSCRPAPLAPFFR	NOTCH3	1346	Q9UM47
CGHPRPASSSPPGDR	MEIOSIN	231	C9JSJ3
KGPPRCSFSPRNSRH	MED26	266	O95402
PCGRPDPSSFSRARE	OPRD1	336	P41143
RRGPSGAAAFLHEPP	FAM171A2	461	A8MVW0
GRCSVPEGPFPRHLV	PCDHB7	721	Q9Y5E2
RPPGICERPHRFSKG	KDM2B	986	Q8NHM5
RPSFLPLCVGGHRPS	BNIP5	471	P0C671
GDRDACRLHPQGRPP	SLC45A1	16	Q9Y2W3
RAHGCFPEGRSPPGA	IRF2BP2	61	Q7Z5L9
RRPPGTAERPGLVCH	COL5A3	1531	P25940
APRGGSPRSQASRPH	nan	456	A6NNC1
PGRGCGHRTARPAAS	NMRK2	211	Q9NPI5
RYGRPPDSHHSRRGP	SRSF2	91	Q01130
PPVRRPGRTSDGHCP	SRGAP1	856	Q7Z6B7
DPRPSHPEPRGCGAA	TACO1	31	Q9BSH4
TGRRSHRAAPPCGFA	FBXL22	216	Q6P050
GRAHSVPTPRPFRGL	NPAP1	36	Q9NZP6
FPTPRARPPDCSGGH	nan	21	P0C879
GRVHAPREGPFTCPH	ZNF646	1751	O15015
PPGLGARCDHFETRP	STAB1	1866	Q9NY15
RHRRTHTGERPFPCP	ZNF316	736	A6NFI3
KHRRGHTGERPFPCP	ZNF316	876	A6NFI3
PRSERGRGRCPFDPS	SEMA3E	161	O15041
GRGRCPHEPSRPFAS	SEMA3G	166	Q9NS98
ASGFPPRCPSGRDHS	nan	101	Q6ZVU0
PRCPSGRDHSRDHPG	nan	106	Q6ZVU0
TLFGHRAPSPAAPRR	nan	186	Q6ZS46
HPGDSGSRRRSPGLC	ZNF318	126	Q5VUA4