Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	heparanase activity	HPSE2 HPSE	5.53e-05	2	149	2	GO:0030305
GeneOntologyBiologicalProcess	developmental growth	CARM1 ACACB INSR NCAM1 CHD7 PTGFRN CHRNA1 AR PTK2 ZFY POSTN ADRB3 PIK3CA SERPINE1 CNTNAP2 LRP6 KDR DMBT1 C9orf72 KDM6A	7.55e-06	911	147	20	GO:0048589
GeneOntologyBiologicalProcess	endocytosis	MRC1 DPP4 PSG6 INSR FCHO2 HPSE LYST PTK2 TULP1 MFGE8 ADRB3 PIK3CA IGHG2 SERPINE1 LRP6 ARHGAP27 DMBT1 C9orf72	2.51e-05	827	147	18	GO:0006897
GeneOntologyBiologicalProcess	receptor-mediated endocytosis	MRC1 DPP4 PSG6 INSR FCHO2 HPSE ADRB3 SERPINE1 LRP6 ARHGAP27 DMBT1	3.09e-05	337	147	11	GO:0006898
GeneOntologyBiologicalProcess	growth	CARM1 ACACB PSG6 INSR NCAM1 CHD7 PTGFRN CHRNA1 AR PTK2 ZFY POSTN ADRB3 PIK3CA SERPINE1 CNTNAP2 LRP6 KDR DMBT1 C9orf72 KDM6A PHIP	6.41e-05	1235	147	22	GO:0040007
GeneOntologyBiologicalProcess	import into cell	CACNA1D MRC1 DPP4 PSG6 INSR FCHO2 HPSE LYST PTK2 TULP1 SLC3A2 MFGE8 ADRB3 PIK3CA IGHG2 SERPINE1 LRP6 ARHGAP27 DMBT1 C9orf72	7.82e-05	1074	147	20	GO:0098657
GeneOntologyBiologicalProcess	animal organ morphogenesis	CARM1 TBX3 COL10A1 PSG6 INSR PCDHA12 CHD7 AHDC1 AR PTK2 TULP1 NCOR2 CELSR1 CSF3R SERPINE1 LRP6 HAND1 KDR CTNS KDM6A UTY HTT	9.54e-05	1269	147	22	GO:0009887
GeneOntologyBiologicalProcess	heart morphogenesis	TBX3 INSR PCDHA12 CHD7 PTK2 NCOR2 LRP6 HAND1 KDM6A UTY	1.05e-04	321	147	10	GO:0003007
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	1.64e-06	12	145	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	1.64e-06	12	145	4	IPR027970
Domain	Cadherin_tail	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	9.39e-06	37	145	5	PF15974
Domain	Cadherin_CBD	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	9.39e-06	37	145	5	IPR031904
Domain	Glyco_hydro_79	HPSE2 HPSE	5.99e-05	2	145	2	IPR005199
Domain	Glyco_hydro_79n	HPSE2 HPSE	5.99e-05	2	145	2	PF03662
Domain	Cadherin_2	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	1.49e-04	65	145	5	PF08266
Domain	Cadherin_N	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	1.49e-04	65	145	5	IPR013164
Domain	-	HPSE2 HPSE SLC3A2 KLB	1.51e-04	35	145	4	3.20.20.80
Domain	Cadherin_CS	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.07e-04	109	145	6	IPR020894
Domain	Glyco_hydro_catalytic_dom	HPSE2 HPSE SLC3A2 KLB	2.10e-04	38	145	4	IPR013781
Domain	CADHERIN_1	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.52e-04	113	145	6	PS00232
Domain	Cadherin	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.52e-04	113	145	6	PF00028
Domain	CADHERIN_2	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.65e-04	114	145	6	PS50268
Domain	-	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.65e-04	114	145	6	2.60.40.60
Domain	CA	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.77e-04	115	145	6	SM00112
Domain	Cadherin-like	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	2.91e-04	116	145	6	IPR015919
Domain	Cadherin	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	3.19e-04	118	145	6	IPR002126
Domain	Glyco_hydro_38_C	MAN2C1 MAN2B2	5.89e-04	5	145	2	IPR011682
Domain	Alpha-mann_mid	MAN2C1 MAN2B2	5.89e-04	5	145	2	PF09261
Domain	Glyco_hydro_57/38_cen	MAN2C1 MAN2B2	5.89e-04	5	145	2	IPR028995
Domain	Glyco_hydro_38	MAN2C1 MAN2B2	5.89e-04	5	145	2	PF01074
Domain	-	MAN2C1 MAN2B2	5.89e-04	5	145	2	1.20.1270.50
Domain	-	MAN2C1 MAN2B2	5.89e-04	5	145	2	3.20.110.10
Domain	Alpha-mann_mid	MAN2C1 MAN2B2	5.89e-04	5	145	2	SM00872
Domain	Glyco_hydro_38_N	MAN2C1 MAN2B2	5.89e-04	5	145	2	IPR000602
Domain	Glyco_hydro_38/57_N	MAN2C1 MAN2B2	5.89e-04	5	145	2	IPR027291
Domain	Glyco_hydro_38_cen	MAN2C1 MAN2B2	5.89e-04	5	145	2	IPR015341
Domain	Glyco_hydro_38C	MAN2C1 MAN2B2	5.89e-04	5	145	2	PF07748
Domain	Glycoside_hydrolase_SF	HPSE2 HPSE SLC3A2 KLB	7.60e-04	53	145	4	IPR017853
Domain	Glyco_hydro/deAcase_b/a-brl	MAN2C1 MAN2B2	1.23e-03	7	145	2	IPR011330
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	8.63e-12	6	151	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	8.63e-12	6	151	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	5.74e-08	24	151	5	32212159
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	4.49e-07	15	151	4	15640798
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	7.48e-07	72	151	6	10380929
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	7.78e-07	17	151	4	29911975
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	9.96e-07	18	151	4	15570159
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	9.96e-07	18	151	4	10662547
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	1.11e-06	77	151	6	10835267
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SEMA4B MAN2B2 ARSK PIEZO1 RECQL LAMP2 ITGA7 PTGFRN ATF6B SLC3A2 USP5 CELSR1 CLPTM1 SERPINE1 LRP6 TMEM131 DSE HTT DNMT1	1.24e-06	1201	151	19	35696571
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 CELSR1	1.40e-06	80	151	6	10716726
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	3.39e-06	24	151	4	24698270
Pubmed	Interaction network of human early embryonic transcription factors.	TBX3 ACACB NUP43 CHD7 AHDC1 LIN9 NCOR2 KDM6A HOMEZ DCAF7	3.43e-06	351	151	10	38297188
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHA12 PCDHA8 PCDHA5 PCDHA1	6.45e-06	28	151	4	15347688
Pubmed	PDGF-B signaling is important for murine cardiac development: its role in developing atrioventricular valves, coronaries, and cardiac innervation.	NCAM1 POSTN KDR	6.61e-06	9	151	3	18213589
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	1.21e-05	68	151	5	11230163
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA12 PCDHA8 PCDHA5	1.29e-05	11	151	3	9655502
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1 SERPINE1	1.40e-05	119	151	6	28625976
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	DPP4 SEMA4B NCAM1 LAMP2 ITIH4 SLC3A2 POSTN CNTN1	1.78e-05	257	151	8	16335952
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	1.83e-05	74	151	5	10817752
Pubmed	Corosolic Acid Inhibits Hepatocellular Carcinoma Cell Migration by Targeting the VEGFR2/Src/FAK Pathway.	PTK2 KDR	1.87e-05	2	151	2	25978354
Pubmed	Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis.	NAA10 AR	1.87e-05	2	151	2	22315407
Pubmed	Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors.	ITGA7 CHRNA1	1.87e-05	2	151	2	10910772
Pubmed	F-actin binding regions on the androgen receptor and huntingtin increase aggregation and alter aggregate characteristics.	AR HTT	1.87e-05	2	151	2	20140226
Pubmed	A common motif targets huntingtin and the androgen receptor to the proteasome.	AR HTT	1.87e-05	2	151	2	18586675
Pubmed	Immunohistochemical expression of heparanases 1 and 2 in benign tissue and in invasive neoplasia of the endometrium: a case-control study.	HPSE2 HPSE	1.87e-05	2	151	2	25423319
Pubmed	The Good and Bad Sides of Heparanase-1 and Heparanase-2.	HPSE2 HPSE	1.87e-05	2	151	2	32274740
Pubmed	Opposing Effects of Heparanase and Heparanase-2 in Head & Neck Cancer.	HPSE2 HPSE	1.87e-05	2	151	2	32274741
Pubmed	Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.	POSTN KDR	1.87e-05	2	151	2	15082792
Pubmed	Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.	PIEZO1 POSTN	1.87e-05	2	151	2	35619555
Pubmed	Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT.	AR NCOR2	1.87e-05	2	151	2	12441355
Pubmed	A C9orf72-CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress.	CARM1 C9orf72	1.87e-05	2	151	2	30366907
Pubmed	Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.	KDM6A UTY	1.87e-05	2	151	2	18434530
Pubmed	PUM1 modulates trophoblast cell proliferation and migration through LRP6.	LRP6 PUM1	1.87e-05	2	151	2	34734756
Pubmed	Expression of NCAM isoforms during skeletal myogenesis in the mouse embryo.	NCAM1 CHRNA1	1.87e-05	2	151	2	1421527
Pubmed	Positive and negative selection on mammalian Y chromosomes.	KDM6A UTY	1.87e-05	2	151	2	15758204
Pubmed	Expression of heparanase isoforms in intervertebral discs classified according to Pfirrmann grading system for disc degeneration.	HPSE2 HPSE	1.87e-05	2	151	2	23370684
Pubmed	Crosstalk between tumor cells and lymphocytes modulates heparanase expression.	HPSE2 HPSE	1.87e-05	2	151	2	30922347
Pubmed	Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma.	HPSE2 HPSE	1.87e-05	2	151	2	36980254
Pubmed	IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux.	ERN1 HTT	1.87e-05	2	151	2	21954231
Pubmed	Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1.	CNTNAP2 CNTN1	1.87e-05	2	151	2	26721881
Pubmed	Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens.	AR NCOR2	1.87e-05	2	151	2	19223455
Pubmed	PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1.	CHRNA1 SERPINE1	1.87e-05	2	151	2	37542348
Pubmed	Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member.	HPSE2 HPSE	1.87e-05	2	151	2	11027606
Pubmed	PI3K is negatively regulated by PIK3IP1, a novel p110 interacting protein.	PIK3IP1 PIK3CA	1.87e-05	2	151	2	17475214
Pubmed	An H-YDb epitope is encoded by a novel mouse Y chromosome gene.	KDM6A UTY	1.87e-05	2	151	2	8944031
Pubmed	HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells.	PTK2 KDR	1.87e-05	2	151	2	15528360
Pubmed	Insulin receptor, IRS1, IRS2, INSIG1, INSIG2, RRAD, and BAIAP2 gene expressions in glioma U87 cells with ERN1 loss of function: effect of hypoxia and glutamine or glucose deprivation.	ERN1 INSR	1.87e-05	2	151	2	23363253
Pubmed	CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells.	DPP4 POSTN	1.87e-05	2	151	2	24747072
Pubmed	βKlotho inhibits androgen/androgen receptor‑associated epithelial‑mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling.	AR KLB	1.87e-05	2	151	2	29749458
Pubmed	Heparanase-2 protein and peptides have a protective effect on experimental glomerulonephritis and diabetic nephropathy.	HPSE2 HPSE	1.87e-05	2	151	2	37180718
Pubmed	Dynein axonemal heavy chain 8 promotes androgen receptor activity and associates with prostate cancer progression.	AR DNAH8	1.87e-05	2	151	2	27363033
Pubmed	Cav1.3 channel α1D protein is overexpressed and modulates androgen receptor transactivation in prostate cancers.	CACNA1D AR	1.87e-05	2	151	2	24054868
Pubmed	Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial growth factor receptor signaling.	AR KDR	1.87e-05	2	151	2	23723256
Pubmed	hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.	NAA10 DNMT1	1.87e-05	2	151	2	20592467
Pubmed	Upregulated Expression of Heparanase and Heparanase 2 in the Brains of Alzheimer's Disease.	HPSE2 HPSE	1.87e-05	2	151	2	28387673
Pubmed	Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.	LAMP2 CTNS	1.87e-05	2	151	2	25586965
Pubmed	Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.	KDM6A UTY	1.87e-05	2	151	2	27533081
Pubmed	Malignant astrocytoma cell attachment and migration to various matrix proteins is differentially sensitive to phosphoinositide 3-OH kinase inhibitors.	PTK2 PIK3CA	1.87e-05	2	151	2	10733346
Pubmed	Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.	KDM6A UTY	1.87e-05	2	151	2	31097364
Pubmed	Elevated plasma plasminogen activator inhibitor-1 in CD36 deficiency.	DPP4 SERPINE1	1.87e-05	2	151	2	18820218
Pubmed	Decidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells.	HPSE2 HPSE	1.87e-05	2	151	2	17989358
Pubmed	The amino terminus of the human AR is target for corepressor action and antihormone agonism.	AR NCOR2	1.87e-05	2	151	2	11923464
Pubmed	Polymorphisms in the KDR and POSTN genes: association with breast cancer susceptibility and prognosis.	POSTN KDR	1.87e-05	2	151	2	16807673
Pubmed	Primary mammary angiosarcomas harbor frequent mutations in KDR and PIK3CA and show evidence of distinct pathogenesis.	PIK3CA KDR	1.87e-05	2	151	2	32123305
Pubmed	Mutations in HPSE2 cause urofacial syndrome.	HPSE2 HPSE	1.87e-05	2	151	2	20560210
Pubmed	Nuclear FAK and its kinase activity regulate VEGFR2 transcription in angiogenesis of adult mice.	PTK2 KDR	1.87e-05	2	151	2	29416084
Pubmed	A high-resolution molecular atlas of the fetal mouse lower urogenital tract.	AR PTK2 LRP6 KDR DNMT1	1.95e-05	75	151	5	21905163
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	PCDHA12 PCDHA8 PCDHA5 PCDHA1 FCHO2	1.95e-05	75	151	5	15372022
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CARM1 TBC1D30 COQ8B DNAH2 SLC28A3 PCDHA5 DGKH RIOX2 EBLN1 HECW2 KAZN ITPRIPL1 DSE	2.12e-05	736	151	13	29676528
Pubmed	Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness.	ITGA7 PTK2 POSTN	2.82e-05	14	151	3	28153048
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ERN1 PIEZO1 PCDHA1 CHD7 LYST TRANK1 PLA2G4B SERGEF SERPINE1 PHIP CACNA2D3	3.17e-05	552	151	11	10737800
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	COL10A1 GPAT3 NAA10 HPSE2 TMC4 CHD7 ITGA7 PUM1 CNTN1	3.20e-05	363	151	9	14691545
Pubmed	KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.	WRAP53 KDM6A UTY	4.31e-05	16	151	3	35212626
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	TBX3 RECQL AR NCOR2 USP5 KDM6A DCAF7	5.26e-05	220	151	7	35785414
Pubmed	The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.	AR NCOR2	5.60e-05	3	151	2	16373395
Pubmed	Phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdomains.	AR PIK3CA	5.60e-05	3	151	2	17635910
Pubmed	Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth.	AR NCOR2	5.60e-05	3	151	2	17356171
Pubmed	Dopamine in vivo inhibits VEGF-induced phosphorylation of VEGFR-2, MAPK, and focal adhesion kinase in endothelial cells.	PTK2 KDR	5.60e-05	3	151	2	15371263
Pubmed	p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors.	INSR PTK2	5.60e-05	3	151	2	9507031
Pubmed	Milk fat globule EGF factor 8 restores mitochondrial function via integrin-medicated activation of the FAK-STAT3 signaling pathway in acute pancreatitis.	PTK2 MFGE8	5.60e-05	3	151	2	33634976
Pubmed	The UTX gene escapes X inactivation in mice and humans.	KDM6A UTY	5.60e-05	3	151	2	9499428
Pubmed	Naa10p promotes cell invasiveness of esophageal cancer by coordinating the c-Myc and PAI1 regulatory axis.	NAA10 SERPINE1	5.60e-05	3	151	2	36433943
Pubmed	Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR-2/PI3K/mTOR pathway in ovarian cancer xenografts.	PIK3CA KDR	5.60e-05	3	151	2	24952635
Pubmed	Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.	HTT DNMT1	5.60e-05	3	151	2	27516062
Pubmed	Glomerular endothelial PI3 kinase-α couples to VEGFR2, but is not required for eNOS activation.	PIK3CA KDR	5.60e-05	3	151	2	21937609
Pubmed	Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer.	AR PIK3CA	5.60e-05	3	151	2	26506516
Pubmed	Repression of androgen receptor transcription through the E2F1/DNMT1 axis.	AR DNMT1	5.60e-05	3	151	2	21966451
Pubmed	iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function.	NCAM1 ASTN2	5.60e-05	3	151	2	26694817
Pubmed	The role of chaperone-mediated autophagy in huntingtin degradation.	LAMP2 HTT	5.60e-05	3	151	2	23071649
Pubmed	Knockdown of IRE1ɑ suppresses metastatic potential of colon cancer cells through inhibiting FN1-Src/FAK-GTPases signaling.	ERN1 PTK2	5.60e-05	3	151	2	31326465
Pubmed	SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells.	DPP4 GRM2	5.60e-05	3	151	2	34903715
Pubmed	A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt.	PTK2 KDR	5.60e-05	3	151	2	21667138
Pubmed	Prognostic value of androgen receptor and FOXA1 co-expression in non-metastatic triple negative breast cancer and correlation with other biomarkers.	AR PIK3CA	5.60e-05	3	151	2	29880907
Pubmed	The vitronectin RGD motif regulates TGF-β-induced alveolar epithelial cell apoptosis.	PTK2 SERPINE1	5.60e-05	3	151	2	27106291
Pubmed	Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development.	AR DNMT1	5.60e-05	3	151	2	25446526
Pubmed	Focal adhesion kinase is required for blood vessel morphogenesis.	PTK2 KDR	5.60e-05	3	151	2	12595342
Pubmed	Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis.	ERN1 KDR	5.60e-05	3	151	2	23529610
Pubmed	Activation of FAK/PI3K/Rac1 signaling controls actin reorganization and inhibits cell motility in human cancer cells.	PTK2 PIK3CA	5.60e-05	3	151	2	17982280
Pubmed	NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn).	NCAM1 PTK2	5.60e-05	3	151	2	9079653
Interaction	BTNL2 interactions	ARSK INSR ITGA7 PTGFRN ATF6B MFGE8 CELSR1 CLPTM1 LRP6 TMEM131	1.83e-07	155	145	10	int:BTNL2
Interaction	LYZL1 interactions	SEMA4B MAN2B2 ARSK INSR MFGE8 CELSR1 LRP6 TMEM131	2.22e-06	118	145	8	int:LYZL1
Interaction	SDF2L1 interactions	DPP4 SEMA4B MAN2B2 ARSK INSR ITGA7 PTGFRN MFGE8 CELSR1 CLPTM1 LRP6 TMEM131	3.82e-06	322	145	12	int:SDF2L1
Interaction	CLEC12B interactions	ERN1 ARSK PIEZO1 ITGA7 PTGFRN ATF6B MFGE8 TMEM131 DSE	7.57e-06	184	145	9	int:CLEC12B
Interaction	CLGN interactions	DPP4 MAN2B2 ARSK PIEZO1 INSR LAMP2 ITGA7 GRM2 ATF6B CLPTM1	8.01e-06	235	145	10	int:CLGN
Interaction	FBXO2 interactions	SEMA4B MAN2B2 ARSK PIEZO1 INSR LAMP2 HPSE PTGFRN ATF6B CLPTM1 TMEM131 CNTN1 HTT	8.86e-06	411	145	13	int:FBXO2
Interaction	KLK2 interactions	MAN2B2 ARSK AR SERPINE1 LRP6	1.24e-05	42	145	5	int:KLK2
Interaction	C1orf54 interactions	SEMA4B MAN2B2 ARSK ITGA7 HPSE CELSR1 TMEM131 DSE	2.86e-05	167	145	8	int:C1orf54
Interaction	ITGB1 interactions	DOK1 DPP4 MAN2C1 INSR NCAM1 LAMP2 ITGA7 PTK2 SLC3A2 USP5 KDR DNAH8	3.34e-05	400	145	12	int:ITGB1
Interaction	TRGV3 interactions	MAN2B2 ARSK ITGA7 MFGE8 CELSR1	4.69e-05	55	145	5	int:TRGV3
Interaction	GGH interactions	MAN2B2 ARSK INSR ITGA7 HPSE CELSR1 CLPTM1 LRP6 TMEM131	6.79e-05	243	145	9	int:GGH
Interaction	GXYLT1 interactions	DPP4 INSR ASPHD2 ITGA7 CLPTM1 LRP6	7.64e-05	98	145	6	int:GXYLT1
Cytoband	5q31	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	4.13e-05	115	151	5	5q31
Cytoband	15q25	SEMA4B MFGE8	2.97e-04	8	151	2	15q25
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	2.97e-04	8	151	2	chr9q12
GeneFamily	Clustered protocadherins	PCDHGC4 PCDHA12 PCDHA8 PCDHA5 PCDHA1	2.50e-05	64	98	5	20
GeneFamily	Mannosidases alpha class 2	MAN2C1 MAN2B2	2.88e-04	5	98	2	1194
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	MRC1 DPP4 INSR NCAM1 LAMP2 PTGFRN CD1E CSF3R KDR	2.88e-04	394	98	9	471
GeneFamily	WD repeat domain containing	NUP43 CFAP43 WRAP53 LYST BRWD3 PHIP DCAF7	5.58e-04	262	98	7	362
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	INSR LMTK2 KDR	1.32e-03	40	98	3	321
GeneFamily	Fibronectin type III domain containing	INSR NCAM1 CSF3R ASTN2 CNTN1	1.79e-03	160	98	5	555
GeneFamily	Dyneins, axonemal	DNAH2 DNAH8	3.75e-03	17	98	2	536
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	PHIP DCAF7	4.20e-03	18	98	2	498
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 PTK2 LRP6 HELZ DAAM1 PUM1 KDM6A PHIP	3.13e-07	192	151	8	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D NCAM1 ADRB3 ASTN2 KDR PRR14L DHTKD1	1.90e-06	170	151	7	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL10A1 PIWIL1 NCAM1 DCT POSTN GPR137C ARNT2	3.09e-06	183	151	7	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 OAS2 DGKH PIK3IP1 HECW2 KDR DAAM1	3.09e-06	183	151	7	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL10A1 PIWIL1 NCAM1 DCT POSTN GPR137C ARNT2	3.09e-06	183	151	7	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	COVID_vent-Myeloid-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN PTK2 CD1E DSE CACNA2D3	3.44e-06	186	151	7	63a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBX3 INSR LMTK2 DGKH POSTN HECW2 DISP1	3.44e-06	186	151	7	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	COVID_vent-Myeloid-Dendritic-cDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN PTK2 CD1E DSE CACNA2D3	3.44e-06	186	151	7	39457a7b43537f2c3e221f9375c95d4515424d7d
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBX3 INSR LMTK2 DGKH POSTN HECW2 DISP1	3.44e-06	186	151	7	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	Control-Lymphoid_B-B_memory\|Control / Disease group, lineage and cell class	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	3.69e-06	188	151	7	ba4245de3bee29118abab57c4fce60b2007a189c
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	3.69e-06	188	151	7	9256c5f45c97df209bb9c322c3b557d4f726a333
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	4.10e-06	191	151	7	03f6da73e7b706252d2096507222229c4101a27b
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	4.10e-06	191	151	7	578b58782e816ecaeabfbc616ceb1dcd53ee428b
ToppCell	VE-mDC2-\|VE / Condition, Cell_class and T cell subcluster	MRC1 INSR GPAT3 CD1E CSF3R DSE CACNA2D3	5.02e-06	197	151	7	6629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCell	VE-mDC2\|VE / Condition, Cell_class and T cell subcluster	MRC1 INSR GPAT3 CD1E CSF3R DSE CACNA2D3	5.02e-06	197	151	7	e3172102ad17c92c3038cad37bf933eb04351048
ToppCell	Control-Control-Lymphocyte-B-B_memory\|Control / Disease, condition lineage and cell class	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	5.37e-06	199	151	7	76976d5f79f324a6c488161847c50f207361d6c6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPB ZFY HECW2 ARNT2 LRP6 CACNA2D3	1.55e-05	156	151	6	5b2781d38a83b4b0f8a53cf321ce5db3a07d0818
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPB ZFY HECW2 ARNT2 LRP6 CACNA2D3	1.55e-05	156	151	6	e0aef6104be16b12304b8e30358f444c1660e92f
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 GPAT3 ASPHD2 CD1E SKOR1 CACNA2D3	1.73e-05	159	151	6	6115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 GPAT3 ASPHD2 CD1E SKOR1 CACNA2D3	1.79e-05	160	151	6	a90eb621481fd07a821495db07d1032e109fd386
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 TBC1D30 PCDHGC4 DGKH HECW2 ASTN2	2.44e-05	169	151	6	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4B DGKH CELSR1 ARNT2 ASTN2 CACNA2D3	2.69e-05	172	151	6	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4B DGKH CELSR1 ARNT2 ASTN2 CACNA2D3	2.69e-05	172	151	6	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B TBX3 CENPB ACOX1 GPAT3 DMBT1	2.78e-05	173	151	6	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B TBX3 CENPB ACOX1 GPAT3 DMBT1	2.78e-05	173	151	6	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP4 EPG5 PIK3IP1 TMEM131 KAZN GSTO1	3.06e-05	176	151	6	d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 GPAT3 E2F2 PTGFRN CD1E CACNA2D3	3.16e-05	177	151	6	cbedac0bddb8fc330a464815c905928c553b0fc0
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_12\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 GPAT3 E2F2 PTGFRN CD1E CACNA2D3	3.26e-05	178	151	6	04bfecf5ea5d85c843e48d08718b5d69e7bf834e
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 ITGA7 POSTN MFGE8 PIK3CA DAAM1	3.58e-05	181	151	6	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 ITGA7 POSTN MFGE8 PIK3CA DAAM1	3.58e-05	181	151	6	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 GPAT3 PTGFRN CD1E GSTO1 DSE	3.70e-05	182	151	6	9a68d3bd1cc9139de9e9e711c249d47ade826bb1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 GPAT3 PTGFRN CD1E GSTO1 DSE	3.70e-05	182	151	6	d57d18732aa6fb7b2d430601568f9ba525ac6e3c
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	MRC1 COL10A1 SLC28A3 POSTN CD1E DSE	3.81e-05	183	151	6	06e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 LAMP2 ADRB3 GPNMB GSTO1 CNTN1	3.81e-05	183	151	6	02deb595819fb864a934fd0fcaad684f1ca42964
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COQ8B GPAT3 ZFP14 CD1E CLEC20A DAAM1	3.93e-05	184	151	6	b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COQ8B GPAT3 ZFP14 CD1E CLEC20A DAAM1	3.93e-05	184	151	6	b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D DPP4 ACACB PTK2 PUM1 KLB	4.05e-05	185	151	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ACACB ARNT2 ASTN2 KAZN CACNA2D3	4.17e-05	186	151	6	1850583d23903d08226aeb0edb3e07b0994330e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ACACB ARNT2 ASTN2 KAZN CACNA2D3	4.17e-05	186	151	6	4dafc215c42e7949f932a3627359c107943b5d6b
ToppCell	COVID_non-vent-Myeloid-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	4.30e-05	187	151	6	936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CACNA1D DPP4 ACACB DNAAF9 LYST PTK2	4.30e-05	187	151	6	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 NCAM1 HPSE2 POSTN GPR137C DISP1	4.30e-05	187	151	6	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	COVID-19_Severe-B_memory\|World / disease group, cell group and cell class	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DNAH8	4.30e-05	187	151	6	f29c71f2505bb64f3010ada491d422b87a6f7db3
ToppCell	COVID_non-vent-Myeloid-Dendritic-cDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	4.30e-05	187	151	6	55fe4e8b4f301876716c1af15c34d42164f2358e
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.43e-05	188	151	6	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PIWIL1 NCAM1 ASPHD2 ITGA7 LRRC4 POSTN	4.43e-05	188	151	6	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	Healthy/Control-B_memory\|Healthy/Control / Disease group and Cell class	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.43e-05	188	151	6	3aff07f77b2b15e7a30e47b30115178abe64474e
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1	4.43e-05	188	151	6	6f53bcd4caab2fc961af799039ea5c3ddae56781
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 CENPB ACOX1 GPAT3 SERPINE1 GPNMB	4.56e-05	189	151	6	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB PTK2 ASTN2 KAZN UTY CACNA2D3	4.56e-05	189	151	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 OAS2 DGKH HECW2 KDR ARHGAP27	4.56e-05	189	151	6	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TBX3 DCT POSTN SERPINE1 KDR KAZN	4.56e-05	189	151	6	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	MRC1 SEMA4B NCOR2 CSF3R DMBT1 CACNA2D3	4.56e-05	189	151	6	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHD7 CHRNA1 IGHG2 DAAM1 DNAH8	4.56e-05	189	151	6	ac0203f17b481d608587113ea2de0f383b29ed27
ToppCell	Healthy_donor-B_memory\|Healthy_donor / disease group, cell group and cell class (v2)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.70e-05	190	151	6	46104a521f00d399315deca86699cb261b2795d6
ToppCell	droplet-Bladder\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 TMC4 PTGFRN SERPINE1 GPNMB GSTO1	4.70e-05	190	151	6	170484f7a6f0a0d0792bbe1bb04abad060b7188e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MRC1 ACACB FCHO2 BRWD3 ZFY UFSP1	4.70e-05	190	151	6	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	CHD7 CHRNA1 IGHG2 CNTNAP2 DAAM1 DNAH8	4.70e-05	190	151	6	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAM1 HPSE2 ITGA7 ITIH4 POSTN SERPINE1	4.70e-05	190	151	6	7df63e5e0dd395676f4fc18cad0d8b2428390943
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDHA12 POSTN IGHG2 GPNMB DISP1 SBK2	4.84e-05	191	151	6	5343a527de6b0f852f45020a91f5b4869e78f13a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDHA12 POSTN IGHG2 GPNMB DISP1 SBK2	4.84e-05	191	151	6	a25a5f9a380031fdaf57677a079f97a90f0550c0
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.84e-05	191	151	6	22134a2c1a92208bc1629a620ce73a56502613c2
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 OAS2 DGKH HECW2 KDR DISP1	4.98e-05	192	151	6	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 NCAM1 HPSE2 POSTN GPR137C DISP1	4.98e-05	192	151	6	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.98e-05	192	151	6	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.98e-05	192	151	6	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	4.98e-05	192	151	6	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TBX3 PTK2 POSTN HECW2 SERPINE1 KDR	5.12e-05	193	151	6	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	mild_COVID-19-B_memory\|mild_COVID-19 / disease group, cell group and cell class (v2)	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	5.12e-05	193	151	6	7e6fe70928a50b0a8f12220e572c07c5670d092e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D GPAT3 CELSR1 ASTN2 KAZN CACNA2D3	5.12e-05	193	151	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 OAS2 DGKH HECW2 KDR DISP1	5.12e-05	193	151	6	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	CHD7 PTK2 PIK3CA IGHG2 TMEM131 DNAH8	5.12e-05	193	151	6	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 PTK2 HELZ PUM1 KDM6A PHIP	5.12e-05	193	151	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 DGKH ARNT2 ASTN2 KAZN CACNA2D3	5.43e-05	195	151	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	COVID-19_Severe-B_memory\|COVID-19_Severe / disease group, cell group and cell class	SEMA4B CHD7 CHRNA1 IGHG2 CNTNAP2 DNAH8	5.43e-05	195	151	6	54becd9e283639638fc5f13eddce224aed9391da
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPP4 DGKH ARNT2 ASTN2 KAZN CACNA2D3	5.43e-05	195	151	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	healthy_donor-Myeloid-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	5.58e-05	196	151	6	ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell	healthy_donor-Myeloid-Dendritic-cDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	5.58e-05	196	151	6	aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 GPAT3 CD1E ADRB3 DSE CACNA2D3	5.74e-05	197	151	6	61bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MRC1 GPAT3 CD1E ADRB3 DSE CACNA2D3	5.74e-05	197	151	6	4f7c10a636646dfc82a84026c1b5a36603367abe
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 GPAT3 CD1E CSF3R DSE CACNA2D3	5.91e-05	198	151	6	898ef4f02443780f9b1fc08b73a165fda0ca5cde
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 GPAT3 CD1E CSF3R DSE CACNA2D3	5.91e-05	198	151	6	c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBX3 POSTN HECW2 SERPINE1 KDR DISP1	5.91e-05	198	151	6	d5990cab01de6e6f3757f5a50ef70ced711bb1fa
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MRC1 GPAT3 CD1E ADRB3 DSE CACNA2D3	5.91e-05	198	151	6	da36c1bb62fdd1da7aca9c5115432a87fb48adb0
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 LAMP2 FCHO2 SLC3A2 GPNMB GSTO1	5.91e-05	198	151	6	885cbd3695b466a161cf318d35ebbdfcc0c19cec
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 GPAT3 CD1E CSF3R DSE CACNA2D3	5.91e-05	198	151	6	bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 GPAT3 CD1E ADRB3 DSE CACNA2D3	6.07e-05	199	151	6	fdd8c4c04837341e17a4772a2adcdf2f187c56b1
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBX3 POSTN HECW2 SERPINE1 KDR DISP1	6.07e-05	199	151	6	6cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_memory\|COVID-19_Mild / Disease, condition lineage and cell class	SEMA4B CHD7 IGHG2 CNTNAP2 DAAM1 DNAH8	6.07e-05	199	151	6	54e392b4ebe601d4838739ff7de3ac6b2203c948
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBX3 SLC3A2 HECW2 SERPINE1 KDR DISP1	6.24e-05	200	151	6	3767abc75176779198505ebc6967d55ce322d9fe
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TBX3 POSTN HECW2 SERPINE1 KDR DISP1	6.24e-05	200	151	6	5ab588808c1fc384019413401ab4bf9bc06bf529
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBX3 SLC3A2 HECW2 SERPINE1 KDR DISP1	6.24e-05	200	151	6	e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCell	Transverse-(5)_Dendritic_cell-(50)_cDC2\|Transverse / shred on region, Cell_type, and subtype	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	6.24e-05	200	151	6	eea523f7512b54d7443651bce3ff6d043a9897aa
ToppCell	Transverse-Dendritic_cell-cDC2\|Transverse / Region, Cell class and subclass	MRC1 GPAT3 PTGFRN CD1E DSE CACNA2D3	6.24e-05	200	151	6	80730a6372627543b84d8fb1b94c481db17c6500
ToppCell	(50)_cDC2\|World / shred on Cell_type and subtype	MRC1 GPAT3 CD1E CSF3R DSE CACNA2D3	7.35e-05	206	151	6	d519adeb8290fcce107e81a439ba3bf1e231b55b
ToppCell	COVID-19-kidney-Epithelial_Doublet\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HPSE2 SPATA31A6 CNTNAP2 KAZN DNAH8	8.14e-05	130	151	5	1ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Rspo3_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PCDHA8 PCDHA1 SKOR1 KLB	9.95e-05	71	151	4	879551882097cfaa4eccf11cb07f3bae68c777c3
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Rspo3_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PCDHA8 PCDHA1 SKOR1 KLB	9.95e-05	71	151	4	8557be86709925cf19125e44c909133fd5adcb62
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 LMTK2 LYST CSF3R CNTN1	1.50e-04	148	151	5	b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 LMTK2 LYST CSF3R CNTN1	1.50e-04	148	151	5	ba277c898678dd36f8dc1d681301c71901b89055
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A	CACNA1D INSR NCAM1 HPSE2 CD1E TRANK1 PRKACG HAND1 KDR KAZN	4.97e-07	200	141	10	5601_UP
Drug	4-methylumbelliferyl	MAN2C1 MAN2B2 ARSK HPSE2 HPSE ZFY POSTN	8.43e-07	83	141	7	CID000011833
Drug	naphthol-AS-BI	MAN2C1 MAN2B2 HPSE2 HPSE NCOR2	3.15e-06	37	141	5	CID000071060
Drug	Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; PC3; HT_HG-U133A	CACNA1D DPP4 ITGA7 DCT PIK3IP1 NCOR2 ARNT2 CNTNAP2 KAZN	3.80e-06	196	141	9	3996_UP
Drug	0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A	DPP4 TBC1D30 PCDHA5 ITGA7 GRM2 CHRNA1 PIK3IP1 ARNT2 DMBT1	3.96e-06	197	141	9	3693_UP
Disease	1,5 anhydroglucitol measurement	PCDHA12 PCDHA8 PCDHA5 PCDHA1	1.18e-05	29	144	4	EFO_0008009
Disease	neutrophil count, basophil count	PCDHA12 PCDHA8 PCDHA5 PCDHA1 CHD7 LIN9 CSF3R DNMT1	1.51e-05	224	144	8	EFO_0004833, EFO_0005090
Disease	Streptozotocin Diabetes	ACOX1 INSR MFGE8 ADRB3 SERPINE1 S1PR4	1.55e-05	108	144	6	C0038433
Disease	Diabetes Mellitus, Experimental	ACOX1 INSR MFGE8 ADRB3 SERPINE1 S1PR4	1.55e-05	108	144	6	C0011853
Disease	Alloxan Diabetes	ACOX1 INSR MFGE8 ADRB3 SERPINE1 S1PR4	1.55e-05	108	144	6	C0002152
Disease	Unipolar Depression	ACSM1 OAS2 NCAM1 DGKH HPSE SERPINE1 CNTNAP2 KDR	4.26e-05	259	144	8	C0041696
Disease	Kabuki syndrome (implicated_via_orthology)	KDM6A UTY	7.07e-05	3	144	2	DOID:0060473 (implicated_via_orthology)
Disease	breast angiosarcoma (is_implicated_in)	PIK3CA KDR	7.07e-05	3	144	2	DOID:4511 (is_implicated_in)
Disease	Bipolar Disorder	CACNA1D NCAM1 DGKH ITIH4 MFGE8 TRANK1 CNTNAP2 ASTN2 DNAH8 DNMT1	1.24e-04	477	144	10	C0005586
Disease	alkaline phosphatase measurement	SEMA4B ACACB ERN1 MOGAT2 TMC4 FCHO2 DCT ITIH4 MFGE8 TRANK1 CLPTM1 PRR14L DMBT1 HOMEZ DNMT1	1.38e-04	1015	144	15	EFO_0004533
Disease	Major Depressive Disorder	ACSM1 OAS2 NCAM1 HPSE SERPINE1 CNTNAP2 KDR	1.99e-04	243	144	7	C1269683
Disease	Insulin Resistance	MRC1 ACACB INSR AR	2.15e-04	60	144	4	C0021655
Disease	Insulin Sensitivity	MRC1 ACACB INSR AR	2.15e-04	60	144	4	C0920563
Disease	neurilemmoma (is_marker_for)	SERPINE1 KDR	2.34e-04	5	144	2	DOID:3192 (is_marker_for)
Disease	migraine disorder, diastolic blood pressure	HPSE2 NCOR2 ASTN2	2.42e-04	25	144	3	EFO_0006336, MONDO_0005277
Disease	Mammary Carcinoma, Human	TBX3 MAN2C1 RECQL HPSE AR MFGE8 PIK3CA KDR GPNMB DNMT1	2.67e-04	525	144	10	C4704874
Disease	Mammary Neoplasms, Human	TBX3 MAN2C1 RECQL HPSE AR MFGE8 PIK3CA KDR GPNMB DNMT1	2.67e-04	525	144	10	C1257931
Disease	Mammary Neoplasms	TBX3 MAN2C1 RECQL HPSE AR MFGE8 PIK3CA KDR GPNMB DNMT1	2.75e-04	527	144	10	C1458155
Disease	breast cancer (is_marker_for)	INSR WRAP53 NCOR2 SERPINE1 KDR KDM6A	3.05e-04	185	144	6	DOID:1612 (is_marker_for)
Disease	Breast Carcinoma	TBX3 MAN2C1 RECQL HPSE AR MFGE8 PIK3CA KDR GPNMB DNMT1	3.24e-04	538	144	10	C0678222
Disease	colorectal cancer (is_implicated_in)	WRAP53 YTHDF1 PIK3CA KDR KDM6A	3.26e-04	121	144	5	DOID:9256 (is_implicated_in)
Disease	leiomyoma (is_implicated_in)	AR PTK2	3.50e-04	6	144	2	DOID:127 (is_implicated_in)
Disease	Tinnitus	RTKN2 SPATA31A1 CNTNAP2 TMEM131 CACNA2D3	4.53e-04	130	144	5	HP_0000360
Disease	fatty liver disease (implicated_via_orthology)	ACACB INSR LRP6	4.63e-04	31	144	3	DOID:9452 (implicated_via_orthology)
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	4.89e-04	7	144	2	DOID:0050580 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_implicated_in)	WRAP53 SLC3A2 KDR KDM6A DNMT1	6.15e-04	139	144	5	DOID:3908 (is_implicated_in)
Disease	arteriosclerosis (biomarker_via_orthology)	ITGA7 KDR	6.50e-04	8	144	2	DOID:2349 (biomarker_via_orthology)
Disease	head and neck squamous cell carcinoma (is_marker_for)	WRAP53 SERPINE1	6.50e-04	8	144	2	DOID:5520 (is_marker_for)
Disease	hippocampal CA3 volume	DPP4 ASTN2 DAAM1	7.22e-04	36	144	3	EFO_0009395
Disease	visceral adipose tissue measurement, body mass index	PCDHA12 PCDHA8 PCDHA5 PCDHA1	8.85e-04	87	144	4	EFO_0004340, EFO_0004765
Disease	Nodular glomerulosclerosis	DGKH SERPINE1 KDR	1.06e-03	41	144	3	C0017667
Disease	alcohol consumption measurement	CACNA1D EEF1AKMT4-ECE2 DPP4 ACACB DNAH2 NCAM1 SLC28A3 WRAP53 NCOR2 SERGEF ASTN2 ARHGAP27 CACNA2D3 HTT KLB	1.13e-03	1242	144	15	EFO_0007878
Disease	myocardial infarction (biomarker_via_orthology)	TBX3 NCAM1 LAMP2 POSTN KDM6A	1.16e-03	160	144	5	DOID:5844 (biomarker_via_orthology)
Disease	neutrophil count	PCDHA12 PCDHA8 E2F2 PCDHA5 DGKH PCDHA1 TMC4 CHD7 PTGFRN LIN9 CD1E CSF3R SERGEF HTT S1PR4 DNMT1	1.20e-03	1382	144	16	EFO_0004833
Disease	Prostatic Intraepithelial Neoplasias	AR DNMT1	1.26e-03	11	144	2	C0282612
Disease	degenerative disc disease (biomarker_via_orthology)	COL10A1 POSTN	1.26e-03	11	144	2	DOID:90 (biomarker_via_orthology)
Disease	Diabetic Nephropathy	DGKH SERPINE1 KDR	1.30e-03	44	144	3	C0011881
Disease	Mood Disorders	CACNA1D NCAM1 AR HTT DNMT1	1.43e-03	168	144	5	C0525045
Disease	persulfide dioxygenase ETHE1, mitochondrial measurement	CYP4V2 ITIH4	1.51e-03	12	144	2	EFO_0008258
Disease	hippocampal CA1 volume	DPP4 ASTN2 DAAM1	1.68e-03	48	144	3	EFO_0009394
Disease	eosinophil measurement	GPAT3 CHD7 TMEM131 CTNS	1.97e-03	108	144	4	EFO_0803540
Disease	hepatocellular carcinoma (biomarker_via_orthology)	CARM1 INSR PIK3CA DNMT1	1.97e-03	108	144	4	DOID:684 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	ERN1 RECQL PIK3CA KDR KDM6A	1.99e-03	181	144	5	DOID:684 (is_implicated_in)
Disease	insulin measurement	TBC1D30 INSR NCAM1 DGKH AR ITIH4	2.04e-03	267	144	6	EFO_0004467
Disease	glycerol-3-phosphate measurement	CFAP43 CNTNAP2	2.38e-03	15	144	2	EFO_0010488
Disease	R-6-hydroxywarfarin measurement	DNAH2 SLC28A3 WRAP53 NCOR2	2.40e-03	114	144	4	EFO_0803327
Disease	Colorectal Carcinoma	PSMA2 LRRC4 POSTN PIK3CA KDR GPNMB DNAH8 KDM6A PHIP CNTN1	2.41e-03	702	144	10	C0009402
Disease	leukemia	AR CSF3R GSTO1	2.48e-03	55	144	3	C0023418
Disease	5-oxoproline measurement	SLC28A3 DNAH8	2.71e-03	16	144	2	EFO_0010988
Disease	migraine without aura, susceptibility to, 4	HPSE2 ASTN2	2.71e-03	16	144	2	MONDO_0011847
Disease	alcohol use disorder (implicated_via_orthology)	CHRNA1 PRKACG GSTO1 KDM6A UTY	2.75e-03	195	144	5	DOID:1574 (implicated_via_orthology)
Disease	Depressive disorder	DPP4 OAS2 NCAM1 HPSE AR HTT	3.03e-03	289	144	6	C0011581
Disease	neutrophil percentage of leukocytes	USP49 DGKH CHD7 TULP1 CSF3R HELZ TMEM131 HTT S1PR4	3.14e-03	610	144	9	EFO_0007990
Disease	post-traumatic stress disorder	PCDHA8 NCAM1 PCDHA5 PCDHA1 KAZN	3.19e-03	202	144	5	EFO_0001358
Disease	Prostatic Neoplasms	TBX3 LMTK2 CHD7 AR PIK3CA SERPINE1 GSTO1 KDM6A DNMT1	3.35e-03	616	144	9	C0033578
Disease	Malignant neoplasm of prostate	TBX3 LMTK2 CHD7 AR PIK3CA SERPINE1 GSTO1 KDM6A DNMT1	3.35e-03	616	144	9	C0376358
Disease	disease free survival	SLC3A2 CNTNAP2	3.44e-03	18	144	2	EFO_0000409
Disease	Malignant Neoplasms	PIK3CA KDR GSTO1 KDM6A	3.64e-03	128	144	4	C0006826
Disease	hepatocellular carcinoma (is_marker_for)	TBX3 INSR RECQL WRAP53 ITIH4 KDR	3.69e-03	301	144	6	DOID:684 (is_marker_for)
Disease	Schizophrenia	ACSM1 NCAM1 GRM2 RTKN2 PIK3CA PLA2G4B CNTNAP2 ASTN2 KDR C9orf72 DNMT1	4.12e-03	883	144	11	C0036341
Disease	response to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement	LMTK2 C9orf72	4.24e-03	20	144	2	EFO_0803359, EFO_0803362
Disease	brain age measurement	EEF1AKMT4-ECE2 EEF1AKMT4	4.24e-03	20	144	2	EFO_0010602
Disease	smoking status measurement	CACNA1D DPP4 LMTK2 NCAM1 SLC28A3 CHD7 PTK2 POSTN HECW2 SERPINE1 CNTNAP2 DNAH8 CNTN1	4.56e-03	1160	144	13	EFO_0006527

Protein segments in the cluster

Peptide	Gene	Start	Entry
NPNLRDNWTDAEGYY	PRPF4B	661	Q13523
LGIYDEGNFSFSNAW	TMEM184C	196	Q9NVA4
TESWNNFKGLDPNYT	ARSK	96	Q6UWY0
TAYFKESPLNQNSGW	EPG5	2331	Q9HCE0
ASYSSLPEFELALWN	CFAP43	126	Q8NDM7
ASALEISYNGEPQSW	DNMT1	1381	P26358
DFASYFQSLDPWNNS	GRM2	326	Q14416
RNEAGLSADPYVYNW	GPNMB	121	Q14956
SNYSQLGTFAPVWDV	FCHO2	61	Q0JRZ9
EYSDWTADAGINLQP	BRWD3	856	Q6RI45
NDNAPQFLWDFYQGS	CELSR1	886	Q9NYQ6
GLDWASEAFSQLYNP	AHDC1	1116	Q5TGY3
PAFLALNWLGYANSA	ADRB3	326	P13945
RQWGHNELDEPFYTN	DHTKD1	431	Q96HY7
PVFNVDGYHFSWTND	CPA6	236	Q8N4T0
HSESNAELGQLYWPN	CHD7	1891	Q9P2D1
GLSNGWFVSNLEFYD	DISP1	961	Q96F81
FDWNEVDPYLLGTSS	DCAF7	126	P61962
SEGSYLDISDWLNPA	ASTN2	481	O75129
LNQPQSEWFGSTLYE	ARNT2	171	Q9HBZ2
GQFYQEVLWGSPAAS	ITIH4	876	Q14624
ENYISLWSIGDFGNL	NUP43	41	Q8NFH3
WRPDLVLYNNADGDF	CHRNA1	106	P02708
GQVWFPDSAYKTAQA	ACACB	2126	O00763
WIGLYHIDENSPANF	HECW2	91	Q9P2P5
FWPSLPADLQAAYEN	MMP27	321	Q9H306
YDQWEESPPLSANAF	NCOR2	2351	Q9Y618
SGYNAWLSYELQPAA	PCDHA8	601	Q9Y5H6
AWLNDIGLSQYSQAF	KAZN	531	Q674X7
WFYSNIDKPLFEGDN	LIN9	126	Q5TKA1
DWQGFLELYLQNSPE	GSTO1	221	P78417
SWNPSYARLDKQGNF	MFGE8	261	Q08431
DWGSPDLNLVHYNQT	LIPJ	276	Q5W064
ESPFNYGWDNLSDKA	GPR137C	276	Q8N3F9
SLEADPNSGQSWYFL	KDM6A	276	O15550
NFWYQPSFHGVDLSA	CARM1	311	Q86X55
LSWPQLSYIAEDENG	NAA10	36	P41227
WNIPYEFNSADFSAS	DNAH8	4071	Q96JB1
DWLYDLLRNNSNFGP	DEPDC1	51	Q5TB30
NTSLGWPNGLALDYD	LRP6	486	O75581
FDNWLTVIPSGAFEY	LRRC4	131	Q9HBW1
PKDYSARWNEIFGNN	DSE	91	Q9UL01
FSIANNNLSYWDAPL	LAMP2	311	P13473
GVTLWELFDNAAQPY	LMTK2	336	Q8IWU2
WSPNGTFLAYAQFND	DPP4	216	P27487
YFQSWLLSPADAAPD	HAND1	41	O96004
NPLDYGSAWAAAAAQ	AR	391	P10275
SDPNGNITHYLVFWE	INSR	646	P06213
AANLQDSLYWASEPS	PLA2G4B	506	P0C869
FWDNGHLYREDQTSP	PIK3IP1	26	Q96FE7
GYNAWVSYQLLEAPD	PCDHGC4	601	Q9Y5F7
VDPDSGYNAWLSYEL	PCDHA5	596	Q9Y5H7
AVLNIPSYAGGTNFW	DGKH	846	Q86XP1
NNLSDSYAAGFLWLN	HPSE2	391	Q8WWQ2
FNALSLNDNPSPWIY	OAS2	146	P29728
YLAPDGAWTFANLQQ	HELZ	1676	P42694
YNISWELGNEPNSFL	HPSE	216	Q9Y251
PLAWGNINLFDYTDT	PIK3CA	421	P42336
DEFGYLSANWNQPPS	MORC2	466	Q9Y6X9
WGVYPASLFQQQAAA	PUM1	466	Q14671
SGYNAWLSYELQPAA	PCDHA1	601	Q9Y5I3
LFDQIPNSSGSWLRY	MOGAT2	231	Q3SYC2
YNWLTDFPSQEALDS	ITPRIPL1	156	Q6GPH6
NKGATSWPEFYIDQL	DAAM1	96	Q9Y4D1
ADLLISYNAGPAIDW	EBLN1	181	P0CF75
WDQRYQGAADSAPYD	EEF1AKMT4-ECE2	26	P0DPD8
GNVYENLFEWAKNSP	ACOX1	626	Q15067
AYQGSDFLSFQGISW	CD1E	141	P15812
DDAYLNSPWADNTAL	CFAP298	261	P57076
NSTPSGEWFTFYLVN	ASPHD2	221	Q6ICH7
ETSLWYDFLPDQAAG	CENPB	196	P07199
AEPAAYWSKLNDLFG	HTT	2196	P42858
DFLYRWGNPAQNTAS	PRKACG	26	P22612
ISFSPSLDQDDYLWG	E2F2	401	Q14209
LENSLYSPTWEGSQF	DOK1	141	Q99704
IKYNPQFGDAFWNSS	GPAT3	331	Q53EU6
SESGDVLWIQNYASP	ERN1	211	O75460
DVLGFPSNQDLYWSE	CCNDBP1	221	O95273
DNFDRDPSLIWQYFG	CACNA2D3	201	Q8IZS8
DPALDLTFVWSFNGY	CNTN1	531	Q12860
AYLYSSNLQSWPEEG	DNAAF9	546	Q5TEA3
LDLTPNYRGENSWFS	SLC3A2	306	P08195
TDPNWANFLYDASSH	COQ8B	366	Q96D53
AAINWSLYLLGSNPE	CYP4V2	336	Q6ZWL3
SYENLWFQASPLGTL	CSF3R	786	Q99062
LQGELEPASFSWTYE	LYST	3056	Q99698
FDWDLGYNLTLNDTS	MAN2B2	801	Q9Y2E5
SEFWLPDTFGYSAQL	MAN2C1	366	Q9NTJ4
WLNPSTAEAFQAYAG	KLB	661	Q86Z14
PSDSDHYQWLQVDFG	CNTNAP2	76	Q9UHC6
FYPSDISVEWESNGQ	IGHG2	251	P01859
YSLAVADLNSDGWPD	ITGA7	366	Q13683
YNNDQWTLIFGDPTK	CTNS	321	O60931
GAFPYQSDFWQHLQS	HOMEZ	211	Q8IX15
QNTGFLAWYNSFPSD	DMBT1	1866	Q9UGM3
LGWNIIYGFNDSDFE	DNAH2	4001	Q9P225
LLADVFGSNLWAQEY	S1PR4	271	O95977
DPFYEDFLIWQASGQ	SBK2	271	P0C263
PKGYFSDAWNTFDSL	CACNA1D	1261	Q01668
GKSPLLAATFAYWDN	C9orf72	21	Q96LT7
STEQLNPYLAASGWD	PRR14L	1666	Q5THK1
SGYNAWLSYELQPAA	PCDHA12	601	Q9UN75
ALYFNGQWKTPFPDS	SERPINE1	191	P05121
ASILDPYSNAFAWLQ	MRC1	1131	P22897
YNPQFADWSKETRGA	PIWIL1	471	Q96J94
ASTWEVGFPAQLYQE	PTGFRN	71	Q9P2B2
SINGNEESSFWLPLY	RTKN2	256	Q8IZC4
DAKYTQPDAANFNSW	SKOR1	231	P84550
QKSLEADPNSGQSWY	UTY	271	O14607
APAAAALFAWGANSY	SERGEF	11	Q9UGK8
EGDTAWNYSFSQLPR	WRAP53	141	Q9BUR4
LAFPSDHATWQGNYS	TBX3	221	O15119
GTKAQDFYNWPDESF	MOB4	16	Q9Y3A3
NYSQLFWGLPSLHSE	SPATA31A6	411	Q5VVP1
ETPDASYLWLLNGQN	PSG6	171	Q00889
YPGQASLLDQTDSWN	PTK2	761	Q05397
NYSQLFWGLPSLHSE	SPATA31A7	411	Q8IWB4
VFFYNPLTGETAWED	ARHGAP27	316	Q6ZUM4
SLNWLQDPAFVASAY	SEMA4B	231	Q9NPR2
SALSWFGNMFDYPQL	SLC28A3	466	Q9HAS3
WDQRYQGAADSAPYD	EEF1AKMT4	26	P0DPD7
SLSEFGAPRWNDYEV	ACSM1	31	Q08AH1
FFTDNLLSPEDWGLQ	ATF6B	16	Q99941
QSTKSPWNFLGDELY	CLPTM1	321	O96005
WLQLPNAESNGLYSS	COL10A1	651	Q03692
AWIGLYLNANSGSLS	CLEC20A	211	Q6ZU45
ISWFRDGQLLPSSNY	NCAM1	446	P13591
GASNEYDSSPAAWNK	RECQL	56	P46063
EPSEYNKNGNSFWLN	ZNF37A	116	P17032
NYSQLFWGLPSLHSE	SPATA31A3	411	Q5VYP0
PVWNDDSGSYTLNFQ	TULP1	466	O00294
DYSDWTADAGINLQP	PHIP	851	Q8WWQ0
NYSQLFWGLPSLHSE	SPATA31A1	411	Q5TZJ5
NYSQLFWGLPSLHSE	SPATA31A5	411	Q5VU36
GWQEVSAAFDPNSFY	UFSP1	111	Q6NVU6
NLLSGEGYLEWSPLF	TMC4	226	Q7Z404
NEFNSGPSYLWESPA	TMEM131	1756	Q92545
WSLIPAFRGYDQQDA	USP49	386	Q70CQ1
LFQSDPSGAYFAWKA	PSMA2	146	P25787
PSLGQNGFQQWYDAL	TBC1D30	226	Q9Y2I9
GNESFALPYWNFATG	DCT	236	P40126
ISTYQNNSWGDFLLD	RIOX2	256	Q8IUF8
ELNVGIDFNWEYPSS	KDR	251	P35968
WENYSNFISLGPSIS	ZFP14	36	Q9HCL3
DFPAYWRNLTGFTDE	PIEZO1	651	Q92508
DLFWSNPTEFDYLNP	TRANK1	526	O15050
SFTYFAPSNEAWDNL	POSTN	131	Q15063
DSAIYNLQWFRQDPG	TRAV21	46	A0A0B4J279
NESWFARQDLGPSYN	TGM6	336	O95932
YGAPEQVDDFWSTAL	USP5	536	P45974
FPYSLNEAPWSTAGD	YTHDF1	66	Q9BYJ9
FVPIAWAAAYGNNSD	ZFY	351	P08048