Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	HEAT	TNPO1 TNPO2 HEATR1 PRKDC	4.76e-05	48	78	4	PF02985
Domain	HEAT	TNPO1 TNPO2 HEATR1 PRKDC	1.01e-04	58	78	4	IPR000357
Domain	Scramblase	PLSCR4 PLSCR2	1.71e-04	5	78	2	PF03803
Domain	Scramblase	PLSCR4 PLSCR2	1.71e-04	5	78	2	IPR005552
Domain	HEAT_REPEAT	TNPO1 TNPO2 HEATR1 PRKDC	2.09e-04	70	78	4	PS50077
Domain	Rap_GAP_dom	RALGAPB RALGAPA2	9.24e-04	11	78	2	IPR000331
Domain	RAPGAP	RALGAPB RALGAPA2	9.24e-04	11	78	2	PS50085
Domain	Cadherin_CS	FAT1 CDHR5 PCDHB1 PCDHGA8	1.12e-03	109	78	4	IPR020894
Domain	CADHERIN_1	FAT1 CDHR5 PCDHB1 PCDHGA8	1.28e-03	113	78	4	PS00232
Domain	CADHERIN_2	FAT1 CDHR5 PCDHB1 PCDHGA8	1.33e-03	114	78	4	PS50268
Domain	-	FAT1 CDHR5 PCDHB1 PCDHGA8	1.33e-03	114	78	4	2.60.40.60
Domain	CA	FAT1 CDHR5 PCDHB1 PCDHGA8	1.37e-03	115	78	4	SM00112
Domain	Cadherin-like	FAT1 CDHR5 PCDHB1 PCDHGA8	1.41e-03	116	78	4	IPR015919
Domain	Cadherin	FAT1 CDHR5 PCDHB1 PCDHGA8	1.51e-03	118	78	4	IPR002126
Domain	IMPORTIN_B_NT	TNPO1 TNPO2	1.52e-03	14	78	2	PS50166
Domain	IBN_N	TNPO1 TNPO2	1.75e-03	15	78	2	PF03810
Domain	IBN_N	TNPO1 TNPO2	1.99e-03	16	78	2	SM00913
Domain	Kringle	LPA PLAU	2.25e-03	17	78	2	IPR000001
Domain	Kringle_CS	LPA PLAU	2.25e-03	17	78	2	IPR018056
Domain	KRINGLE_2	LPA PLAU	2.25e-03	17	78	2	PS50070
Domain	Kringle	LPA PLAU	2.25e-03	17	78	2	PF00051
Domain	KRINGLE_1	LPA PLAU	2.25e-03	17	78	2	PS00021
Domain	Importin-beta_N	TNPO1 TNPO2	2.25e-03	17	78	2	IPR001494
Domain	KR	LPA PLAU	2.25e-03	17	78	2	SM00130
Domain	ARM-type_fold	TNPO1 CEBPZ TNPO2 HEATR1 PRKDC RALGAPA2	2.93e-03	339	78	6	IPR016024
Domain	Pentatricopeptide_repeat	PRKDC GNAS	4.12e-03	23	78	2	IPR002885
Domain	EGF_CA	FAT1 THBS3 FBLN2	5.59e-03	86	78	3	PF07645
Domain	EGF_Ca-bd_CS	FAT1 THBS3 FBLN2	7.80e-03	97	78	3	IPR018097
Domain	Kringle-like	LPA PLAU	7.87e-03	32	78	2	IPR013806
Domain	EGF_CA	FAT1 THBS3 FBLN2	8.25e-03	99	78	3	PS01187
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TNPO1 ATP6V1B2 FAT1 FOXRED2 AFAP1 ADRM1 CSNK2B AKAP13 NUP214 PSMD11 PRKDC GNAS IKBKB ARHGEF17	1.42e-06	1297	80	14	33545068
Pubmed	A-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophy.	AKAP13 IKBKB	5.23e-06	2	80	2	23090968
Pubmed	Adipocytes contain a novel complex similar to the tuberous sclerosis complex.	RALGAPB RALGAPA2	5.23e-06	2	80	2	16490346
Pubmed	Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.	TNPO1 TNPO2	5.23e-06	2	80	2	9298975
Pubmed	Transportin-1 and Transportin-2: protein nuclear import and beyond.	TNPO1 TNPO2	5.23e-06	2	80	2	24780099
Pubmed	Targeting NF-κB in glioblastoma: A therapeutic approach.	PRKDC IKBKB	5.23e-06	2	80	2	26824076
Pubmed	CK2 negatively regulates Galphas signaling.	CSNK2B GNAS	5.23e-06	2	80	2	19666609
Pubmed	Lactational competence and involution of the mouse mammary gland require plasminogen.	LPA PLAU	1.57e-05	3	80	2	11003846
Pubmed	Evaluation of nuclear factor-kappaB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma.	PLAU IKBKB	1.57e-05	3	80	2	15217951
Pubmed	DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties.	PRKDC IKBKB	1.57e-05	3	80	2	9632806
Pubmed	The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis.	LPA PLAU	1.57e-05	3	80	2	15743790
Pubmed	Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo.	LPA PLAU	1.57e-05	3	80	2	11929773
Pubmed	Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.	CD38 PRKDC	1.57e-05	3	80	2	16585549
Pubmed	Plasminogen directs the pleiotropic effects of uPA in liver injury and repair.	LPA PLAU	1.57e-05	3	80	2	12431907
Pubmed	Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair.	NR4A2 PRKDC	1.57e-05	3	80	2	21979916
Pubmed	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.	RALGAPB RALGAPA2	1.57e-05	3	80	2	19520869
Pubmed	Aspirin Inhibits IKK-β-mediated Prostate Cancer Cell Invasion by Targeting Matrix Metalloproteinase-9 and Urokinase-Type Plasminogen Activator.	PLAU IKBKB	1.57e-05	3	80	2	28278500
Pubmed	ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.	TNPO1 TNPO2	1.57e-05	3	80	2	20606625
Pubmed	Involvement of transportin 2-mediated HuR import in muscle cell differentiation.	TNPO1 TNPO2	1.57e-05	3	80	2	17475777
Pubmed	TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.	MED15 ADRM1 PSMD11	2.01e-05	23	80	3	29581427
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TNPO1 ATP6V1B2 CEBPZ CSNK2B NUP214 PSMD11 HEATR1 PRKDC GNAS ATP1B1 ITPR3	2.24e-05	1024	80	11	24711643
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TNPO1 CYP1B1 AFAP1 CEBPZ TNPO2 CSNK2B PSMD11 HEATR1 PRKDC GNAS IKBKB ATP1B1 ITPR3	2.37e-05	1440	80	13	30833792
Pubmed	Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation.	LPA PLAU	3.13e-05	4	80	2	19210287
Pubmed	Plasminogen activator induction facilitates recovery of respiratory function following spinal cord injury.	LPA PLAU	3.13e-05	4	80	2	18042398
Pubmed	The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import.	TNPO1 TNPO2	3.13e-05	4	80	2	10875935
Pubmed	Identification of three new members of the phospholipid scramblase gene family.	PLSCR4 PLSCR2	3.13e-05	4	80	2	10930526
Pubmed	Mice lacking tPA, uPA, or plasminogen genes showed delayed functional recovery after sciatic nerve crush.	LPA PLAU	3.13e-05	4	80	2	11404420
Pubmed	Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.	ATP6V1B2 CREBBP	3.13e-05	4	80	2	25713363
Pubmed	Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair.	LPA PLAU	3.13e-05	4	80	2	19286661
Pubmed	Beneficial and detrimental effects of plasmin(ogen) during infection and sepsis in mice.	LPA PLAU	3.13e-05	4	80	2	21931850
Pubmed	CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.	TRAF3IP2 IKBKB	3.13e-05	4	80	2	10962033
Pubmed	The role of plasminogen in angiogenesis in vivo.	LPA PLAU	3.13e-05	4	80	2	12911578
Pubmed	Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.	LPA PLAU	3.13e-05	4	80	2	21326869
Pubmed	Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell.	PLSCR4 PLSCR2	3.13e-05	4	80	2	19540310
Pubmed	Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.	LPA PLAU	3.13e-05	4	80	2	16763560
Pubmed	HDAC3 is a critical negative regulator of long-term memory formation.	NR4A2 CREBBP	3.13e-05	4	80	2	21228185
Pubmed	Oncostatin M and IL-6 induce u-PA and VEGF in prostate cancer cells and correlate in vivo.	OSM PLAU	3.13e-05	4	80	2	21965736
Pubmed	Karyopherin beta 2B participates in mRNA export from the nucleus.	TNPO1 TNPO2	3.13e-05	4	80	2	12384575
Pubmed	Plasminogen mediates the pathological effects of urokinase-type plasminogen activator overexpression.	LPA PLAU	3.13e-05	4	80	2	15161662
Pubmed	Plasminogen Activator Inhibitor-1 Protects Mice Against Cardiac Fibrosis by Inhibiting Urokinase-type Plasminogen Activator-mediated Plasminogen Activation.	LPA PLAU	3.13e-05	4	80	2	28336948
Pubmed	Plasmin is essential in preventing periodontitis in mice.	LPA PLAU	3.13e-05	4	80	2	21704601
Pubmed	OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators.	TRAF3IP2 IKBKB	3.13e-05	4	80	2	24561578
Pubmed	Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator.	LPA PLAU	3.13e-05	4	80	2	16554301
Pubmed	Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.	TNPO1 TNPO2	3.13e-05	4	80	2	15037768
Pubmed	Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling.	TNPO1 TIMM23B MOV10L1 PSMD11 PRKDC	4.20e-05	166	80	5	34687317
Pubmed	Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice.	LPA PLAU	5.20e-05	5	80	2	18957535
Pubmed	A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.	AKAP13 PRKDC	5.20e-05	5	80	2	29298866
Pubmed	Role of the adaptor protein CIKS in the activation of the IKK complex.	TRAF3IP2 IKBKB	5.20e-05	5	80	2	12943667
Pubmed	Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.	LPA PLAU	5.20e-05	5	80	2	21273553
Pubmed	Deficiency of urokinase-type plasminogen activator-mediated plasmin generation impairs vascular remodeling during hypoxia-induced pulmonary hypertension in mice.	LPA PLAU	5.20e-05	5	80	2	11306532
Pubmed	Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization.	LPA PLAU	5.20e-05	5	80	2	12657615
Pubmed	The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection.	LPA PLAU	5.20e-05	5	80	2	12875972
Pubmed	Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue.	OSM PRKDC	5.20e-05	5	80	2	34301760
Pubmed	The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent.	LPA PLAU	5.20e-05	5	80	2	11818362
Pubmed	The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system.	LPA PLAU	5.20e-05	5	80	2	10880388
Pubmed	Nuclear role of I kappa B Kinase-gamma/NF-kappa B essential modulator (IKK gamma/NEMO) in NF-kappa B-dependent gene expression.	IKBKB CREBBP	5.20e-05	5	80	2	14597638
Pubmed	Urokinase-type plasminogen activator (uPA) regulates the expression and function of growth-associated protein 43 (GAP-43) in the synapse.	LPA PLAU	5.20e-05	5	80	2	31819012
Pubmed	DNA-PK: gatekeeper for IKKγ/NEMO nucleocytoplasmic shuttling in genotoxic stress-induced NF-kappaB activation.	PRKDC IKBKB	5.20e-05	5	80	2	31932854
Pubmed	IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma.	PRKDC IKBKB	5.20e-05	5	80	2	29588349
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ATP6V1B2 FOXRED2 CEBPZ TNPO2 CSNK2B RALGAPB NUP214 HEATR1 ATP1B1	5.93e-05	754	80	9	33060197
Pubmed	Coregulated ataxia telangiectasia-mutated and casein kinase sites modulate cAMP-response element-binding protein-coactivator interactions in response to DNA damage.	CSNK2B CREBBP	7.79e-05	6	80	2	17209043
Pubmed	Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex.	PRKDC CREBBP	7.79e-05	6	80	2	9488450
Pubmed	Synergy between a plasminogen cascade and MMP-9 in autoimmune disease.	LPA PLAU	7.79e-05	6	80	2	15841177
Pubmed	Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice.	LPA PLAU	7.79e-05	6	80	2	10318667
Pubmed	ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.	PRKDC IKBKB	7.79e-05	6	80	2	14966265
Pubmed	Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.	CSNK2B PRKDC	7.79e-05	6	80	2	11883897
Pubmed	Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.	NR4A2 CREBBP	7.79e-05	6	80	2	15961999
Pubmed	The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.	CSNK2B PRKDC	7.79e-05	6	80	2	10951572
Pubmed	Expression of the phospholipid scramblase (PLSCR) gene family during the acute phase response.	PLSCR4 PLSCR2	7.79e-05	6	80	2	17590392
Pubmed	Karyopherin beta2 mediates nuclear import of a mRNA binding protein.	TNPO1 NUP214	7.79e-05	6	80	2	9144189
Pubmed	Telomere protection by TPP1/POT1 requires tethering to TIN2.	POT1 PRKDC	1.09e-04	7	80	2	22099311
Pubmed	A unique SUMO-2-interacting motif within LANA is essential for KSHV latency.	PRKDC CREBBP	1.09e-04	7	80	2	24278015
Pubmed	Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.	CSNK2B IKBKB	1.09e-04	7	80	2	20797629
Pubmed	A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action.	RALGAPB RALGAPA2	1.09e-04	7	80	2	21148297
Pubmed	Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases.	TRAF3IP2 IKBKB	1.09e-04	7	80	2	12133833
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TNPO1 MED15 ATP6V1B2 CEBPZ FASTK CSNK2B NUP214 PSMD11 PRKDC GNAS ITPR3	1.31e-04	1247	80	11	27684187
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	ATP6V1B2 AFAP1 CSNK2B NUP214 HEATR1 PRKDC GNAS ITPR3	1.41e-04	660	80	8	32780723
Pubmed	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.	IKBKB CREBBP	1.45e-04	8	80	2	11971985
Pubmed	Insulin-like growth factor II receptor, transforming growth factor-beta, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis.	LPA PLAU	1.45e-04	8	80	2	9438420
Pubmed	The Tissue Fibrinolytic System Contributes to the Induction of Macrophage Function and CCL3 during Bone Repair in Mice.	LPA PLAU	1.45e-04	8	80	2	25893677
Pubmed	Negative feedback regulation of NF-κB action by CITED2 in the nucleus.	IKBKB CREBBP	1.45e-04	8	80	2	21098220
Pubmed	High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci.	LPA ITPR3	1.45e-04	8	80	2	7894168
Pubmed	Casein kinase II interacts with the bZIP domains of several transcription factors.	CSNK2B CREBBP	1.45e-04	8	80	2	9685505
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	PCNX3 ZNF644 AKAP13 PLAU SPPL2B	1.48e-04	217	80	5	34048709
Pubmed	Interaction network of human early embryonic transcription factors.	TNPO1 MED15 TNPO2 ZNF644 NUP214 CREBBP	1.62e-04	351	80	6	38297188
Pubmed	Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase.	CSNK2B PRKDC	1.86e-04	9	80	2	10747897
Pubmed	A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells.	NR4A2 CREBBP	1.86e-04	9	80	2	22539306
Pubmed	The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease.	TNPO1 PSMD11	1.86e-04	9	80	2	21983832
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAT1 PCNX3 TIMM23B AKAP13 NUP214 PRKDC LRRK1 SPPL2B RALGAPA2 ITPR3	2.21e-04	1105	80	10	35748872
Pubmed	The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.	ADRM1 PSMD11	2.32e-04	10	80	2	24121268
Pubmed	Transcription is required for establishment of germline methylation marks at imprinted genes.	IMPACT GNAS	2.32e-04	10	80	2	19136628
Pubmed	Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.	CYP1B1 CYP2R1	2.32e-04	10	80	2	15752708
Pubmed	Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation.	IKBKB CREBBP	2.32e-04	10	80	2	15808510
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	ATP6V1B2 GALC PCNX3 FASTK PSMD11 HEATR1 LBP CPLANE1	2.83e-04	732	80	8	34732716
Pubmed	UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts.	CSNK2B PRKDC	2.84e-04	11	80	2	11709713
Pubmed	Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c.	ADRM1 PSMD11	2.84e-04	11	80	2	28396413
Pubmed	Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.	FZD3 ATP1B1	2.84e-04	11	80	2	28746879
Pubmed	A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.	LPA PLAU	2.84e-04	11	80	2	26647393
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TNPO1 FOXRED2 ADRM1 CEBPZ NUP214 PSMD11 HEATR1 PRKDC ITPR3	3.14e-04	942	80	9	31073040
Pubmed	Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.	IKBKB CREBBP	3.40e-04	12	80	2	15383283
Cytoband	2p22.2	CYP1B1 CEBPZ	3.10e-04	15	80	2	2p22.2
GeneFamily	Phospholipid scramblases	PLSCR4 PLSCR2	8.38e-05	5	53	2	954
GeneFamily	Cadherin related	FAT1 CDHR5	1.11e-03	17	53	2	24
GeneFamily	Armadillo repeat containing\|Importins	TNPO1 TNPO2	1.25e-03	18	53	2	596
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP3 FBLN2 FZD3 GPR75 SEMA5A PKHD1L1	9.06e-07	183	79	6	ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OSM FBLN2 FBP1 NR4A2 PLAU ATP1B1	1.20e-06	192	79	6	dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OSM FBLN2 FBP1 NR4A2 PLAU ATP1B1	1.20e-06	192	79	6	d39133cf1a20af6f2970188630fc3b27a4cfc9c5
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLSCR4 CYP1B1 NUP210L RALGAPA2 PKHD1L1	1.16e-05	166	79	5	941d6aa94ab9d36e5f6c40f446c926754e070d56
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLSCR4 CYP1B1 NUP210L RALGAPA2 PKHD1L1	1.16e-05	166	79	5	6f5ecf3b2cf613ae0535ab3d21d93622f1497571
ToppCell	droplet-Kidney\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 CDHR5 PLSCR2 ATP1B1	1.72e-05	180	79	5	7e5f497699876ac8e1ce780626c6f5a1f6f5f079
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC25A41 FBLN2 GPR75 PLAU ARHGEF17	1.96e-05	185	79	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	droplet-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 CDHR5 PLSCR2 ATP1B1	2.07e-05	187	79	5	236e9857729670e87eed30fad58f49e1f56e4a85
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP3 FAT1 THBS3 SEMA5A ATP1B1	2.34e-05	192	79	5	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	COVID-19_Severe-cDC\|COVID-19_Severe / disease group, cell group and cell class	OSM FBLN2 FBP1 NR4A2 ATP1B1	2.52e-05	195	79	5	6419090b19de7b5d5140eaecf231860273da2c0d
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP3 FAT1 THBS3 SEMA5A ATP1B1	2.59e-05	196	79	5	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	IIH-granulo1-\|IIH / Condition, Cell_class and T cell subcluster	CYP1B1 ATP6V1B2 FBP1 LRRC25 NUP214	2.65e-05	197	79	5	51be6d5652b17c70f3a33f244efc3b728ec56f5b
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP1B1 OSM LRRC25 NR4A2 NUP214	2.65e-05	197	79	5	f431f11196dc4332933b5d71c7c7408d54c2dedc
ToppCell	VE-mDC2-\|VE / Condition, Cell_class and T cell subcluster	FBP1 LRRC25 NR4A2 PLAU ATP1B1	2.65e-05	197	79	5	6629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCell	IIH-granulo1\|IIH / Condition, Cell_class and T cell subcluster	CYP1B1 ATP6V1B2 FBP1 LRRC25 NUP214	2.65e-05	197	79	5	39637e8b726bc58c0a6885c49713111f97aff881
ToppCell	LPS_anti-TNF\|World / Treatment groups by lineage, cell group, cell type	ATP6V1B2 OSM LRRC25 NUP210L PLAU	2.65e-05	197	79	5	7768e613fa48a6ec4a3902559310b51345a7fe91
ToppCell	VE-mDC2\|VE / Condition, Cell_class and T cell subcluster	FBP1 LRRC25 NR4A2 PLAU ATP1B1	2.65e-05	197	79	5	e3172102ad17c92c3038cad37bf933eb04351048
ToppCell	distal-Endothelial-Vein-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PLSCR4 CYP1B1 AFAP1 RALGAPA2 PKHD1L1	2.85e-05	200	79	5	ff88d28162e0231d5dac0e0c6bec98fa8da58a23
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP1B1 FBLN2 CARD6 LBP	1.19e-04	142	79	4	6a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP1B1 FBLN2 CARD6 LBP	1.19e-04	142	79	4	671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP1B1 FBLN2 CARD6 LBP	1.19e-04	142	79	4	3557084150670fd2e2634fc674f228ab85181b59
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP1B1 FBLN2 CARD6 LBP	1.19e-04	142	79	4	a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAT1 FBLN2 SEMA5A CACNG5	1.58e-04	153	79	4	9c6fce56300ba5053efda59a438d63a808c497c0
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FBLN2 OR6C74 LBP ATP1B1	1.67e-04	155	79	4	ab539c04f10276ae919d82b1c75f99a84eb695bf
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FBLN2 OR6C74 LBP ATP1B1	1.67e-04	155	79	4	9a27558c457f05808af07190b7a5006b047f1d58
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CYP1B1 FBLN2 LRRK1 LBP	1.84e-04	159	79	4	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 PLSCR2 ATP1B1	1.84e-04	159	79	4	c34a7d227dbda2d7c76f937e1a58552b14bd40b5
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF3IP2 POT1 NR4A2 CPLANE1	1.88e-04	160	79	4	55f599df6e3b7a5a505df4b094c834281311d94a
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF3IP2 POT1 NR4A2 CPLANE1	1.88e-04	160	79	4	296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	1.93e-04	161	79	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	1.93e-04	161	79	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	OSM FBLN2 PDE6A NR4A2	1.93e-04	161	79	4	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	1.93e-04	161	79	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OSM FBLN2 PDE6A NR4A2	1.93e-04	161	79	4	78cc5bc488bc47726195a649946d414e6bfabf94
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OSM FBLN2 PDE6A NR4A2	1.97e-04	162	79	4	0fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	1.97e-04	162	79	4	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	2.12e-04	165	79	4	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	2.12e-04	165	79	4	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	2.12e-04	165	79	4	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLAU LBP GNAS PKHD1L1	2.12e-04	165	79	4	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VPS13D LRRC25 ZNF644 ARHGEF17	2.12e-04	165	79	4	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 PLAU LBP GNAS	2.21e-04	167	79	4	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 PLAU LBP GNAS	2.21e-04	167	79	4	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 PLAU LBP GNAS	2.21e-04	167	79	4	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBLN2 PLAU LBP GNAS	2.21e-04	167	79	4	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	facs-Kidney\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 CDHR5 PLSCR2	2.27e-04	168	79	4	d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC25 NR4A2 NMUR1 PLSCR2	2.27e-04	168	79	4	b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CYP1B1 FBLN2 STRIP2	2.37e-04	170	79	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUP210L LMLN TTC21B SPPL2B	2.37e-04	170	79	4	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CYP1B1 FBLN2 STRIP2	2.37e-04	170	79	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CYP1B1 FBLN2 STRIP2	2.37e-04	170	79	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALC PDE6A CD38 LRRC4B	2.48e-04	172	79	4	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALC PDE6A CD38 LRRC4B	2.48e-04	172	79	4	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NUP210L CD38 TTC21B PLSCR2	2.53e-04	173	79	4	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CHCHD10 THBS3 FBP1 ATP1B1	2.59e-04	174	79	4	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FBLN2 CD38 LRRC4B STRIP2	2.65e-04	175	79	4	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FBLN2 CD38 LRRC4B STRIP2	2.65e-04	175	79	4	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 PLSCR2 ATP1B1	2.65e-04	175	79	4	13843bfc8efe7c01f19ebb6735609c1eec09c698
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBP1 PLAU LBP PKHD1L1	2.65e-04	175	79	4	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBP1 PLAU LBP PKHD1L1	2.65e-04	175	79	4	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CHCHD10 THBS3 FBP1 ATP1B1	2.70e-04	176	79	4	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	facs-Kidney-nan-18m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 CDHR5 ATP1B1	2.76e-04	177	79	4	7f58286fc8797e9bdcf8ece0849f55680905955d
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN2 PDE6A NR4A2 LBP	2.88e-04	179	79	4	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RALGAPB TTC21B HEATR1 ATP1B1	2.88e-04	179	79	4	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	FAT1 AFAP1 SEMA5A PKHD1L1	2.95e-04	180	79	4	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	droplet-Kidney-nan-18m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 PLSCR2 ATP1B1	2.95e-04	180	79	4	cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CHCHD10 PLAU GNAS ATP1B1	2.95e-04	180	79	4	40f79b4455dbd1c2720dc32d9d77c70f835cecb3
ToppCell	droplet-Kidney-KIDNEY\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 PLSCR2 ATP1B1	3.01e-04	181	79	4	3a8c2bc0199b8fe2235ada14672bd31153d5a682
ToppCell	droplet-Kidney-nan-21m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHCHD10 FBP1 PLSCR2 ATP1B1	3.07e-04	182	79	4	942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	TRAF3IP2 ATP1B1 RALGAPA2 PKHD1L1	3.07e-04	182	79	4	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	IPF-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	FAT1 AFAP1 SEMA5A PKHD1L1	3.14e-04	183	79	4	7df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	VPS13D CD38 SEMA5A ARHGEF17	3.14e-04	183	79	4	273db6a3b00a93ca852498471187b642b5368185
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CLIP3 THBS3 ARHGEF17	3.27e-04	185	79	4	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLSCR4 FBLN2 IMPACT ITPR3	3.27e-04	185	79	4	87151ab95530e70d61328b336518df58db584acb
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	FAT1 AFAP1 SEMA5A PKHD1L1	3.27e-04	185	79	4	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CLIP3 THBS3 ARHGEF17	3.27e-04	185	79	4	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLSCR4 CLIP3 THBS3 ARHGEF17	3.27e-04	185	79	4	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATP6V1B2 GALC LRRC25 PLAU	3.27e-04	185	79	4	42690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OSM GPR75 NR4A2 NMUR1	3.34e-04	186	79	4	e083356f72995645f873ca0157d56bea5e942044
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 CLIP3 THBS3 FBLN2	3.34e-04	186	79	4	7c1807fca590cdccf7f5734460bac228d33964ca
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 THBS3 FBLN2 LBP	3.40e-04	187	79	4	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1B2 OSM FBP1 NUP214	3.40e-04	187	79	4	cbe25fb3fc8ed6245dc767c884c298c89a774cce
ToppCell	(04)_Pre-ciliated-(3)_72hpi\|(04)_Pre-ciliated / shred by cell type and Timepoint	CHCHD10 VPS13D GALC DLEC1	3.47e-04	188	79	4	f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 FBLN2 PLAU LBP	3.47e-04	188	79	4	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBP1 NUP210L NR4A2 ATP1B1	3.47e-04	188	79	4	5e13725136114e42d3b59647cf25e0f3c53abb54
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 CLIP3 THBS3 FBLN2	3.54e-04	189	79	4	544d95df910f1b276995624509a7e41b219baca0
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 CLIP3 THBS3 FBLN2	3.54e-04	189	79	4	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	OSM FBLN2 PLAU ATP1B1	3.54e-04	189	79	4	c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCell	RA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	FAT1 NR4A2 PLAU LBP	3.54e-04	189	79	4	b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 FBLN2 PLAU LBP	3.54e-04	189	79	4	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 CLIP3 THBS3 FBLN2	3.54e-04	189	79	4	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1B2 SLC25A41 CHCHD10 FBP1	3.54e-04	189	79	4	131a36e2c900b3b22ba920e0658815e8e278e87d
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PLSCR4 CYP1B1 RALGAPA2 PKHD1L1	3.54e-04	189	79	4	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	OSM FBLN2 PLAU ATP1B1	3.54e-04	189	79	4	807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIP3 NR4A2 CACNG5 ARHGEF17	3.62e-04	190	79	4	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	10x5'-Lung-Myeloid_Monocytic-Classical_monocytes\|Lung / Manually curated celltypes from each tissue	CYP1B1 OSM LRRC25 NUP214	3.62e-04	190	79	4	a2574f0876ebae3a1d2a39a79cc6cadac8ee1688
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBLN2 AFAP1 SEMA5A LRRK1	3.62e-04	190	79	4	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 CLIP3 FBLN2 PKHD1L1	3.62e-04	190	79	4	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS3 FBLN2 PLAU LBP	3.62e-04	190	79	4	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	wk_20-22-Hematologic-Myeloid-Neutrophil\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CYP1B1 OSM LRRC25 NUP214	3.62e-04	190	79	4	5da4a90f56f66567614d84b9b437f559006ea51c
Drug	AC1MHEDK	TNPO1 FBLN2 LPA LMLN AKAP13	2.03e-05	94	80	5	CID003002889
Drug	carnosol	CYP1B1 NR4A2 IKBKB	4.56e-05	20	80	3	ctd:C068623
Drug	Fluticasone propionate [80474-14-2]; Down 200; 8uM; HL60; HT_HG-U133A	CYP1B1 NR4A2 IMPACT PLAU PSMD11 LRRK1	5.46e-05	189	80	6	2928_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A	TRAF3IP2 CYP1B1 AKAP13 LRRK1 GNAS IKBKB	5.46e-05	189	80	6	5084_DN
Drug	Chrysene-1,4-quinone [100900-16-1]; Up 200; 15.4uM; HL60; HG-U133A	CYP1B1 FBP1 FASTK PSMD11 LRRK1 ATP1B1	5.78e-05	191	80	6	1773_UP
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	CYP1B1 SEMA5A PLAU GNAS IKBKB SPPL2B	6.13e-05	193	80	6	5119_DN
Drug	Gibberellic acid [77-06-5]; Down 200; 11.6uM; PC3; HT_HG-U133A	TRAF3IP2 THBS3 AKAP13 NUP214 SPPL2B CPLANE1	6.49e-05	195	80	6	4234_DN
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A	CYP1B1 VPS13D TNPO2 SEMA5A SPPL2B ARHGEF17	6.49e-05	195	80	6	4597_DN
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A	VPS13D AKAP13 PLAU GNAS SPPL2B ARHGEF17	6.49e-05	195	80	6	6101_DN
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; PC3; HT_HG-U133A	THBS3 AFAP1 CYP2R1 NR4A2 SEMA5A LRRK1	6.67e-05	196	80	6	5102_DN
Drug	3-aminobenzamide; Up 200; 10000uM; MCF7; HG-U133A	CYP1B1 FOXRED2 FASTK TNPO2 DLEC1 LBP	6.67e-05	196	80	6	590_UP
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A	VPS13D NR4A2 SEMA5A LBP ARHGEF17 CREBBP	6.67e-05	196	80	6	6060_UP
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A	MED15 VPS13D NR4A2 AKAP13 PSMD11 ARHGEF17	6.67e-05	196	80	6	5577_DN
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HG-U133A	VPS13D FASTK IMPACT AKAP13 IKBKB ITPR3	6.67e-05	196	80	6	1912_UP
Drug	Felbinac [5728-52-9]; Up 200; 18.8uM; PC3; HT_HG-U133A	CYP1B1 CYP2R1 TNPO2 LPA GPR75 NMUR1	6.86e-05	197	80	6	4639_UP
Drug	NU1025; Up 200; 100uM; MCF7; HG-U133A	CYP1B1 VPS13D FOXRED2 CD38 DLEC1 LRRK1	6.86e-05	197	80	6	313_UP
Drug	Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; PC3; HT_HG-U133A	CYP1B1 VPS13D CYP2R1 NR4A2 SEMA5A ARHGEF17	6.86e-05	197	80	6	5796_DN
Drug	Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A	MED15 TRAF3IP2 CYP1B1 THBS3 VPS13D AKAP13	7.06e-05	198	80	6	6362_DN
Drug	Famotidine [76824-35-6]; Down 200; 11.8uM; PC3; HT_HG-U133A	THBS3 FZD3 TNPO2 NR4A2 SEMA5A SPPL2B	7.26e-05	199	80	6	6665_DN
Drug	Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT_HG-U133A	NR4A2 NUP214 LRRK1 SPPL2B ARHGEF17 ITPR3	7.26e-05	199	80	6	2120_UP
Disease	intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)	TNPO1 TNPO2	6.04e-06	2	73	2	DOID:0081262 (implicated_via_orthology)
Disease	Epstein Barr viral capsid antigen seropositivity	GALC CACNG5	2.15e-04	9	73	2	EFO_0009272
Disease	Squamous cell carcinoma	CYP1B1 CSNK2B PRKDC CREBBP	2.58e-04	124	73	4	C0007137
Disease	Thromboembolism	LPA PLAU	3.92e-04	12	73	2	C0040038
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	CYP1B1 NUP214 CREBBP	4.72e-04	61	73	3	C1961102
Disease	Arthritis, Psoriatic	TRAF3IP2 NR4A2	5.39e-04	14	73	2	C0003872
Disease	Lymphoma, Large-Cell, Follicular	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C0079758
Disease	Lymphoma, Follicular, Grade 2	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	ATP6V1B2 CREBBP	6.21e-04	15	73	2	C1956130
Disease	systemic lupus erythematosus	GALC LRRC25 PCNX3 CSNK2B PLAU CDHR5 LRRK1 IKBKB	7.95e-04	799	73	8	MONDO_0007915
Disease	corneal resistance factor	TRAF3IP2 HSD17B7 FBLN2 AFAP1 AKAP13 ATP1B1	8.85e-04	451	73	6	EFO_0010067
Disease	central corneal thickness	TRAF3IP2 CYP1B1 AFAP1 AKAP13 LRRK1	1.02e-03	309	73	5	EFO_0005213
Disease	Lymphoma, Follicular	ATP6V1B2 CREBBP	1.11e-03	20	73	2	C0024301
Disease	Familial aplasia of the vermis	TTC21B CPLANE1	1.11e-03	20	73	2	cv:C0431399
Disease	acute myeloid leukemia (is_implicated_in)	DLEC1 NUP214 CREBBP	1.20e-03	84	73	3	DOID:9119 (is_implicated_in)
Disease	Deep Vein Thrombosis	LPA PLAU	1.23e-03	21	73	2	C0149871
Disease	Venous Thrombosis	LPA PLAU	1.23e-03	21	73	2	C0042487
Disease	type 1 diabetes mellitus (is_implicated_in)	CYP2R1 CD38 ITPR3	1.24e-03	85	73	3	DOID:9744 (is_implicated_in)
Disease	spermatogenic failure (is_implicated_in)	USP26 MOV10L1	1.48e-03	23	73	2	DOID:0111910 (is_implicated_in)
Disease	Coronary heart disease	LPA PLAU	1.61e-03	24	73	2	C0010068
Disease	intraocular pressure measurement	TRAF3IP2 AFAP1 AKAP13 PLAU DLEC1 ATP1B1	1.64e-03	509	73	6	EFO_0004695
Disease	Squamous cell carcinoma of esophagus	FAT1 DLEC1 CREBBP	1.71e-03	95	73	3	C0279626
Disease	Impaired glucose tolerance	CYP1B1 IKBKB	1.75e-03	25	73	2	C0271650
Disease	chromatid-type aberration frequency	SEMA5A GNAS	1.89e-03	26	73	2	EFO_0009862
Disease	Disorder of eye	CYP1B1 PDE6A TTC21B CPLANE1	1.91e-03	212	73	4	C0015397
Disease	Adenoid Cystic Carcinoma	FAT1 PRKDC CREBBP	1.98e-03	100	73	3	C0010606
Disease	Weight Gain	VPS13D FBLN2 LBP	2.09e-03	102	73	3	C0043094

Protein segments in the cluster

Peptide	Gene	Start	Entry
GLPNLGNTCYMNAVL	USP26	296	Q9BXU7
GQNALYNMIEICLNP	TTC21B	1056	Q7Z4L5
SGGCLPVYMRQNINP	LINC00114	111	Q6XXX2
VMKYNPNVLPVQCTG	ATP1B1	201	P05026
QPQMELPLQGCNITY	AFAP1	191	Q8N556
MKLNPQQAPLYGDCV	AKAP13	1	Q12802
AALGLPYMNQPQTQL	CREBBP	486	Q92793
LLVRPPGTMAQAQYC	CDHR5	16	Q9HBB8
YQPLMKLGTQTVPCN	CD38	106	P28907
PQPNYADMLISQEGC	PCDHGA8	771	Q9Y5G5
IIDCVQGPPAMLQAY	ITPR3	891	Q14573
MILYPLQNGTLPCND	PCDHB1	561	Q9Y5F3
GYMQPLKQPENSVLC	ARHGEF17	1091	Q96PE2
CMDSIYLNGQELPLN	FAT1	3976	Q14517
RLNYLPLEQQFMPCL	FASTK	286	Q14296
AICNPLRYPLLMTNI	OR10X1	141	Q8NGY0
LYPNMNLELQGSVPS	LBP	331	P18428
YMGCDLPPALQSLQN	MOV10L1	1171	Q9BXT6
YLGPQQTELFMPICA	NMUR1	51	Q9HB89
LAPNDLPLLAMEYCQ	IKBKB	86	O14920
YTLKGMCPLNTPQQA	LRRK1	1606	Q38SD2
QPVYCNLQSLGQAPM	LRRC25	281	Q8N386
AGYANLCPNMISTQP	LMLN	246	Q96KR4
ESNPNLGYPCNHVML	FBLN2	536	P98095
RNMINSSCDQPLGYP	PCNX3	1766	Q9H6A9
LNCPPGLEYLSQIDM	PLSCR2	81	Q9NRY7
MANCPPGLEYLVQLD	PLSCR4	106	Q9NRQ2
AICNPLRYLTVMNPQ	OR4Q3	126	Q8NH05
LPAYVAQNGLICNIM	PDE6A	346	P16499
NPSLQQPMYIFLGIL	OR56B1	61	Q8NGI3
PLVSQAQALPGQMLY	MED15	326	Q96RN5
GVLCPFYMINQNPGV	NUP214	396	P35658
LPPFCQQGYLRMQGL	FOXRED2	611	Q8IWF2
NLNEPSLTPCGMNYD	RALGAPA2	1541	Q2PPJ7
TLCLQVMLPNEYPGT	IMPACT	51	Q9P2X3
GDPIQCAMPALYRNQ	GPR75	261	O95800
PPLLMGLQLDFCAAN	OR6C74	156	A6NCV1
SPNGKLRLLYECNPM	FBP1	271	P09467
SLQMNSNYPALLKCP	CACNG5	251	Q9UF02
NPIYLGLNGLNLCLM	IL36A	61	Q9UHA7
SNMYQCQFALPLLLP	CARD6	396	Q9BX69
MAAYFTNQQLCILPP	CPLANE1	946	Q9H799
PLQMGPCAYEIRQFL	CHCHD10	96	Q8WYQ3
GMTLQPQPYLICAER	CYP2R1	486	Q6VVX0
PNAGLIMNYCRNPDP	LPA	866	P08519
RVYCENQPMLPIGLS	CSNK2B	111	P67870
CIYLNAGIMPNPQLN	HSD17B7	86	P56937
CQDLPYNTTFMPNLL	FZD3	36	Q9NPG1
CMGDQPNLPYVLAFL	CYP1B1	371	Q16678
RCLEPLPQEQGNMEY	HEATR1	1236	Q9H583
TLPNYDNVPGNLMLS	CLIP3	276	Q96DZ5
SQGMLGPYQQLCIDI	DLEC1	1191	Q9Y238
QLPYGRCGLMTAQEP	GALC	316	P54803
QQMPPFICGALYLVS	CEBPZ	596	Q03701
YLNLGMCNLKDIPNL	LRRC4B	211	Q9NT99
QLFYPECQPEQILMP	NUP210L	1291	Q5VU65
PCLYQMPLSGQQSSI	NR4A2	76	P43354
LDIMGQPINPQCRIY	ATP6V1B2	151	P21281
QTICLPSMYNDPQFG	PLAU	296	P00749
PCEILYQGMLYSLPQ	STRIP2	501	Q9ULQ0
CLYGNNMSGQRDIPP	GNAS	6	Q5JWF2
YCPPKLQATLDMQSG	PSMD11	201	O00231
VQPMQYFDLTCQLLG	POT1	156	Q9NUX5
LPNMLGIIPYACTDL	SLC25A41	246	Q8N5S1
ICNPLRYPVIMTNQL	OR6Y1	131	Q8NGX8
PNILGLRNNIYCMAQ	OSM	141	P13725
MPCLGPSLEYQECNI	SEMA5A	821	Q13591
CRKVNEYLNNPPMPG	ADRM1	121	Q16186
QRYPACAQMLPPNLS	TRAF3IP2	251	O43734
LIQACTMQQLPVPYQ	RNF44	156	Q7L0R7
GYVCPQEVAPMLQQF	TNPO2	786	O14787
LMQRGQPALLYLVPC	SPPL2B	466	Q8TCT7
LTGMNPLCPYLNVDP	TIMM23B	36	Q5SRD1
MPCELLIPQSDNLYG	PKHD1L1	196	Q86WI1
IDGYPDQALPCMDNN	THBS3	461	P49746
SGMPQELNQYPCLKH	RALGAPB	316	Q86X10
LGYVCPQEVAPMLQQ	TNPO1	786	Q92973
MANDLPPYDPQCGIQ	PRKDC	2281	P78527
CVLPLNEDSPLMYQP	ZNF644	1206	Q9H582
CKELLIPPGTQNYMV	VPS13D	3236	Q5THJ4