Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-disulfide reductase activity	PDIA3 STAB1 PDIA4 P4HB QSOX2	1.46e-06	36	109	5	GO:0015035
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 IRF5 ZSCAN25 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	3.19e-06	1244	109	21	GO:0000978
GeneOntologyMolecularFunction	disulfide oxidoreductase activity	PDIA3 STAB1 PDIA4 P4HB QSOX2	3.61e-06	43	109	5	GO:0015036
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 IRF5 ZSCAN25 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	4.46e-06	1271	109	21	GO:0000987
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, transposing S-S bonds	PDIA3 PDIA4 P4HB QSOX2	5.70e-06	22	109	4	GO:0016864
GeneOntologyMolecularFunction	protein disulfide isomerase activity	PDIA3 PDIA4 P4HB QSOX2	5.70e-06	22	109	4	GO:0003756
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors	PDIA3 STAB1 PDIA4 P4HB QSOX2	1.48e-05	57	109	5	GO:0016667
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 IRF5 ZSCAN25 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	2.21e-05	1412	109	21	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 IRF5 ZSCAN25 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	3.59e-05	1459	109	21	GO:0000977
GeneOntologyMolecularFunction	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	PRKCE PRKCH	8.83e-05	3	109	2	GO:0004699
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity	PDIA3 PDIA4 P4HB QSOX2	2.66e-04	57	109	4	GO:0016860
GeneOntologyMolecularFunction	thiol oxidase activity	P4HB QSOX2	4.37e-04	6	109	2	GO:0016972
GeneOntologyMolecularFunction	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	P4HB QSOX2	1.57e-03	11	109	2	GO:0016670
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	SCRT2 KLF12 ZNF140 ZBTB45 KLF17 ZNF682 ZNF572	1.88e-03	320	109	7	GO:0001227
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA3 PLXNA1	1.88e-03	12	109	2	GO:0017154
GeneOntologyMolecularFunction	tumor necrosis factor receptor activity	TNFRSF11A EDA2R	1.88e-03	12	109	2	GO:0005031
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	SCRT2 KLF12 ZNF140 ZBTB45 KLF17 ZNF682 ZNF572	2.09e-03	326	109	7	GO:0001217
GeneOntologyBiologicalProcess	negative regulation of Ras protein signal transduction	SPRY1 RASA3 RASA4 RASA4B	1.37e-05	28	109	4	GO:0046580
GeneOntologyBiologicalProcess	olfactory nerve formation	PLXNA3 PLXNA1	2.77e-05	2	109	2	GO:0021628
GeneOntologyBiologicalProcess	negative regulation of small GTPase mediated signal transduction	SPRY1 RIPOR2 RASA3 RASA4 RASA4B	2.80e-05	67	109	5	GO:0051058
GeneOntologyBiologicalProcess	regulation of GTPase activity	PLXNA3 SPRY1 RIPOR2 RASA3 TBC1D8B RASA4 SIPA1L1 RASA4B PLXNA1	7.25e-05	335	109	9	GO:0043087
GeneOntologyBiologicalProcess	salivary gland development	HGF SEMA3C MUC19 PLXNA1	7.77e-05	43	109	4	GO:0007431
GeneOntologyBiologicalProcess	olfactory nerve morphogenesis	PLXNA3 PLXNA1	8.27e-05	3	109	2	GO:0021627
GeneOntologyBiologicalProcess	response to bacterium	AICDA PELI3 MUC19 RAET1G PELI1 IRF5 ADAMTS13 TNFRSF11A PTGER2 RBCK1 STAB1 HPR DEFB132 PRKCE DMBT1	9.44e-05	916	109	15	GO:0009617
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	PLXNA3 SEMA4B SEMA3C PLXNA1	1.64e-04	52	109	4	GO:0071526
GeneOntologyBiologicalProcess	exocrine system development	HGF SEMA3C MUC19 PLXNA1	2.35e-04	57	109	4	GO:0035272
GeneOntologyBiologicalProcess	cellular response to tumor necrosis factor	PELI3 ADAMTS13 TNFRSF11A RBCK1 BRCA1 ADAMTS7 EDA2R	2.41e-04	233	109	7	GO:0071356
GeneOntologyBiologicalProcess	innate immune response activating cell surface receptor signaling pathway	PELI1 ZNRF1 PRKCE KLRC2 KLRC3	2.60e-04	107	109	5	GO:0002220
GeneOntologyBiologicalProcess	positive regulation of protein folding	PDIA3 PDIA4	2.74e-04	5	109	2	GO:1903334
GeneOntologyBiologicalProcess	dichotomous subdivision of terminal units involved in salivary gland branching	SEMA3C PLXNA1	2.74e-04	5	109	2	GO:0060666
GeneOntologyBiologicalProcess	defense response to bacterium	AICDA PELI3 MUC19 RAET1G RBCK1 STAB1 HPR DEFB132 DMBT1	3.00e-04	405	109	9	GO:0042742
GeneOntologyBiologicalProcess	regulation of Ras protein signal transduction	SPRY1 RASA3 RASA4 RASA4B	3.05e-04	61	109	4	GO:0046578
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	SPRY1 RIPOR2 RASA3 OBSCN PRAG1 RASA4 SIPA1L1 RASA4B	3.92e-04	333	109	8	GO:0051056
GeneOntologyBiologicalProcess	regulation of extrinsic apoptotic signaling pathway	SCRT2 HGF PELI3 PDIA3 RBCK1 BRCA1	4.03e-04	181	109	6	GO:2001236
GeneOntologyBiologicalProcess	regulation of Toll signaling pathway	PELI3 PELI1	4.09e-04	6	109	2	GO:0008592
GeneOntologyBiologicalProcess	branching involved in salivary gland morphogenesis	HGF SEMA3C PLXNA1	4.27e-04	28	109	3	GO:0060445
GeneOntologyBiologicalProcess	response to tumor necrosis factor	PELI3 ADAMTS13 TNFRSF11A RBCK1 BRCA1 ADAMTS7 EDA2R	4.45e-04	258	109	7	GO:0034612
GeneOntologyBiologicalProcess	extrinsic apoptotic signaling pathway	SCRT2 HGF PELI3 PDIA3 RBCK1 BRCA1 CD27	4.55e-04	259	109	7	GO:0097191
Domain	-	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	2.29e-10	679	107	21	3.30.160.60
Domain	zf-C2H2	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	3.32e-10	693	107	21	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	3.41e-10	694	107	21	IPR013087
Domain	ZINC_FINGER_C2H2_2	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	2.47e-09	775	107	21	PS50157
Domain	ZINC_FINGER_C2H2_1	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	2.59e-09	777	107	21	PS00028
Domain	Znf_C2H2-like	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	3.97e-09	796	107	21	IPR015880
Domain	Znf_C2H2	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	4.84e-09	805	107	21	IPR007087
Domain	ZnF_C2H2	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	5.17e-09	808	107	21	SM00355
Domain	Prot_disulphide_isomerase	PDIA3 PDIA4 P4HB	7.28e-07	4	107	3	IPR005792
Domain	-	PLXNA3 RASA3 RASA4 RASA4B	1.76e-06	16	107	4	1.10.506.10
Domain	RasGAP_dom	PLXNA3 RASA3 RASA4 RASA4B	2.93e-06	18	107	4	IPR001936
Domain	KRAB	ZNF132 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZNF256 ZNF611 ZNF624 ZNF682 ZFP82	8.78e-06	369	107	11	SM00349
Domain	KRAB	ZNF132 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZNF256 ZNF611 ZNF624 ZNF682 ZFP82	9.01e-06	370	107	11	IPR001909
Domain	Disulphide_isomerase	PDIA3 PDIA4 P4HB	1.00e-05	8	107	3	IPR005788
Domain	zf-C2H2_6	SCRT2 ZNF845 ZNF140 ZNF181 ZNF256 ZNF611 ZNF624 ZNF682 ZFP82 ZNF572	1.30e-05	314	107	10	PF13912
Domain	BTK	RASA3 RASA4 RASA4B	1.50e-05	9	107	3	SM00107
Domain	Znf_Btk_motif	RASA3 RASA4 RASA4B	1.50e-05	9	107	3	IPR001562
Domain	BTK	RASA3 RASA4 RASA4B	1.50e-05	9	107	3	PF00779
Domain	ZF_BTK	RASA3 RASA4 RASA4B	1.50e-05	9	107	3	PS51113
Domain	Sema	PLXNA3 SEMA4B SEMA3C PLXNA1	2.84e-05	31	107	4	SM00630
Domain	Semap_dom	PLXNA3 SEMA4B SEMA3C PLXNA1	2.84e-05	31	107	4	IPR001627
Domain	Sema	PLXNA3 SEMA4B SEMA3C PLXNA1	2.84e-05	31	107	4	PF01403
Domain	Thioredoxin	PDIA3 PDIA4 P4HB QSOX2	2.84e-05	31	107	4	PF00085
Domain	SEMA	PLXNA3 SEMA4B SEMA3C PLXNA1	2.84e-05	31	107	4	PS51004
Domain	TSP_1	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.03e-05	63	107	5	PF00090
Domain	PET_testin	TES LMCD1	3.25e-05	2	107	2	IPR033724
Domain	TSP1	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.53e-05	65	107	5	SM00209
Domain	TSP1_rpt	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.53e-05	65	107	5	IPR000884
Domain	TSP1	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.53e-05	65	107	5	PS50092
Domain	KRAB	ZNF132 ZNF845 ZNF140 ZNF235 ZNF181 ZNF256 ZNF611 ZNF624 ZNF682 ZFP82	3.99e-05	358	107	10	PS50805
Domain	KRAB	ZNF132 ZNF845 ZNF140 ZNF235 ZNF181 ZNF256 ZNF611 ZNF624 ZNF682 ZFP82	3.99e-05	358	107	10	PF01352
Domain	Thioredoxin	PDIA3 PDIA4 P4HB	5.01e-05	13	107	3	IPR005746
Domain	RasGAP	RASA3 RASA4 RASA4B	6.36e-05	14	107	3	SM00323
Domain	RasGAP_CS	RASA3 RASA4 RASA4B	6.36e-05	14	107	3	IPR023152
Domain	EGF_CA	LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	7.25e-05	122	107	6	SM00179
Domain	RasGAP	RASA3 RASA4 RASA4B	7.91e-05	15	107	3	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA3 RASA4 RASA4B	7.91e-05	15	107	3	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA3 RASA4 RASA4B	7.91e-05	15	107	3	PS50018
Domain	EGF-like_Ca-bd_dom	LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	7.93e-05	124	107	6	IPR001881
Domain	EGF	LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	8.67e-05	126	107	6	PF00008
Domain	Thioredoxin_domain	PDIA3 PDIA4 P4HB QSOX2	8.76e-05	41	107	4	IPR013766
Domain	Pellino	PELI3 PELI1	9.72e-05	3	107	2	PF04710
Domain	-	RASA4 RASA4B	9.72e-05	3	107	2	4.10.1130.10
Domain	Pellino_fam	PELI3 PELI1	9.72e-05	3	107	2	IPR006800
Domain	THIOREDOXIN_2	PDIA3 PDIA4 P4HB QSOX2	1.06e-04	43	107	4	PS51352
Domain	PSI	PLXNA3 SEMA4B SEMA3C PLXNA1	1.16e-04	44	107	4	IPR016201
Domain	Thioredoxin_CS	PDIA3 PDIA4 P4HB	1.17e-04	17	107	3	IPR017937
Domain	PSI	PLXNA3 SEMA4B SEMA3C PLXNA1	1.38e-04	46	107	4	SM00423
Domain	Rho_GTPase_activation_prot	PLXNA3 RASA3 RASA4 RASA4B PLXNA1	1.51e-04	88	107	5	IPR008936
Domain	PLAC	ADAMTS7 ADAMTSL4 ADAMTSL2	1.66e-04	19	107	3	PS50900
Domain	PLAC	ADAMTS7 ADAMTSL4 ADAMTSL2	1.66e-04	19	107	3	IPR010909
Domain	Prot_kin_PKC_delta	PRKCE PRKCH	1.94e-04	4	107	2	IPR014376
Domain	TNFR_c6	TNFRSF11A CD27 EDA2R	2.60e-04	22	107	3	PF00020
Domain	ADAM_spacer1	ADAMTS7 ADAMTSL4 ADAMTSL2	2.98e-04	23	107	3	IPR010294
Domain	ADAM_spacer1	ADAMTS7 ADAMTSL4 ADAMTSL2	2.98e-04	23	107	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS13 ADAMTS7 ADAMTSL2	3.39e-04	24	107	3	IPR013273
Domain	THIOREDOXIN_1	PDIA3 PDIA4 P4HB	3.84e-04	25	107	3	PS00194
Domain	EGF	LAMA2 LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	4.10e-04	235	107	7	SM00181
Domain	TNFR	TNFRSF11A CD27 EDA2R	4.32e-04	26	107	3	SM00208
Domain	PET	TES LMCD1	4.80e-04	6	107	2	PF06297
Domain	PET_domain	TES LMCD1	4.80e-04	6	107	2	IPR010442
Domain	PET	TES LMCD1	4.80e-04	6	107	2	PS51303
Domain	EGF-like_dom	LAMA2 LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	5.79e-04	249	107	7	IPR000742
Domain	TNFR_NGFR_1	TNFRSF11A CD27 EDA2R	5.99e-04	29	107	3	PS00652
Domain	TNFR_NGFR_2	TNFRSF11A CD27 EDA2R	5.99e-04	29	107	3	PS50050
Domain	LIM	TES LMCD1 LDB3 FHL3	6.61e-04	69	107	4	PF00412
Domain	-	PLXNA3 SEMA4B SEMA3C FBXW12 DNAI3 WDHD1 STRN4 PLXNA1	6.62e-04	333	107	8	2.130.10.10
Domain	EGF_1	LAMA2 LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	6.66e-04	255	107	7	PS00022
Domain	WD40/YVTN_repeat-like_dom	PLXNA3 SEMA4B SEMA3C FBXW12 DNAI3 WDHD1 STRN4 PLXNA1	6.89e-04	335	107	8	IPR015943
Domain	-	TES LMCD1 LDB3 FHL3	6.98e-04	70	107	4	2.10.110.10
Domain	Znf_LIM	TES LMCD1 LDB3 FHL3	7.37e-04	71	107	4	IPR001781
Domain	LIM_DOMAIN_1	TES LMCD1 LDB3 FHL3	7.37e-04	71	107	4	PS00478
Domain	LIM_DOMAIN_2	TES LMCD1 LDB3 FHL3	7.37e-04	71	107	4	PS50023
Domain	LIM	TES LMCD1 LDB3 FHL3	7.37e-04	71	107	4	SM00132
Domain	EGF-like_CS	LAMA2 LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	7.64e-04	261	107	7	IPR013032
Domain	PSI	PLXNA3 SEMA4B PLXNA1	8.03e-04	32	107	3	PF01437
Domain	Plexin_repeat	PLXNA3 SEMA4B PLXNA1	8.03e-04	32	107	3	IPR002165
Domain	EGF_2	LAMA2 LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	8.35e-04	265	107	7	PS01186
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF11A CD27 EDA2R	8.80e-04	33	107	3	IPR001368
Domain	C2	RASA3 RASA4 PRKCE RASA4B PRKCH	9.44e-04	131	107	5	PF00168
Domain	Plexin_cytopl	PLXNA3 PLXNA1	1.14e-03	9	107	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA1	1.14e-03	9	107	2	IPR013548
Domain	Plexin	PLXNA3 PLXNA1	1.14e-03	9	107	2	IPR031148
Domain	C2	RASA3 RASA4 PRKCE RASA4B PRKCH	1.15e-03	137	107	5	SM00239
Domain	LAM_G_DOMAIN	LAMA2 EYS FAT2	1.33e-03	38	107	3	PS50025
Domain	C2	RASA3 RASA4 PRKCE RASA4B PRKCH	1.35e-03	142	107	5	PS50004
Domain	Laminin_G_2	LAMA2 EYS FAT2	1.55e-03	40	107	3	PF02210
Domain	-	RASA3 RASA4 PRKCE RASA4B PRKCH	1.62e-03	148	107	5	2.60.40.150
Domain	-	SVEP1 STAB1	1.73e-03	11	107	2	2.40.155.10
Domain	GFP-like	SVEP1 STAB1	1.73e-03	11	107	2	IPR023413
Domain	Laminin_G_1	LAMA2 EYS	1.73e-03	11	107	2	PF00054
Domain	LamG	LAMA2 EYS FAT2	2.04e-03	44	107	3	SM00282
Domain	-	LAMA2 SVEP1 EYS FAT2	2.17e-03	95	107	4	2.60.120.200
Domain	EGF_3	LRP1B SVEP1 STAB1 MMRN1 EYS FAT2	2.34e-03	235	107	6	PS50026
Domain	C2_dom	RASA3 RASA4 PRKCE RASA4B PRKCH	2.54e-03	164	107	5	IPR000008
Domain	PLAC	ADAMTSL4 ADAMTSL2	2.83e-03	14	107	2	PF08686
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP1B SVEP1 MMRN1 EYS	3.23e-03	106	107	4	IPR000152
Domain	SCAN	ZNF444 ZSCAN25 ZSCAN21	4.07e-03	56	107	3	SM00431
Domain	CUB_dom	ADAMTS13 ZZEF1 DMBT1	4.27e-03	57	107	3	IPR000859
Domain	SCAN_BOX	ZNF444 ZSCAN25 ZSCAN21	4.49e-03	58	107	3	PS50804
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	2.41e-06	39	79	5	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	2.41e-06	39	79	5	MM15165
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC19 ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.27e-05	109	79	6	MM15164
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	3.85e-05	68	79	5	M27303
Pathway	REACTOME_SURFACTANT_METABOLISM	LMCD1 ADGRF5 DMBT1	2.77e-04	23	79	3	MM15279
Pubmed	Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells.	PDIA3 PDIA4 P4HB	3.08e-08	3	110	3	9493907
Pubmed	Mapping of three members of the mouse protein disulfide isomerase family.	PDIA3 CHRNA1 PDIA4 P4HB	4.60e-08	12	110	4	9457688
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PLXNA3 KLF12 TES LMCD1 IRF5 ZNF235 LDB3 BRCA1 ZSCAN21 KLF5 ZNRF1 KLF17 FHL3 PLXNA1	5.71e-08	709	110	14	22988430
Pubmed	Disulphide production by Ero1α-PDI relay is rapid and effectively regulated.	PDIA3 PDIA4 P4HB	6.11e-07	6	110	3	20802462
Pubmed	pH dependence of the peptide thiol-disulfide oxidase activity of six members of the human protein disulfide isomerase family.	PDIA3 PDIA4 P4HB	6.11e-07	6	110	3	16677074
Pubmed	Glycosaminoglycans and protein disulfide isomerase-mediated reduction of HIV Env.	PDIA3 PDIA4 P4HB	6.11e-07	6	110	3	15644496
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	PLXNA3 SEMA4B SEMA3C PLXNA1	9.59e-07	24	110	4	15869472
Pubmed	Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry.	PDIA3 PDIA4 P4HB	1.07e-06	7	110	3	12218051
Pubmed	Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection.	PDIA3 PDIA4 P4HB	1.07e-06	7	110	3	23206338
Pubmed	Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase.	PDIA3 PDIA4 P4HB	1.07e-06	7	110	3	20458450
Pubmed	Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding.	PDIA3 PDIA4 P4HB	1.07e-06	7	110	3	17301129
Pubmed	Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion.	PDIA3 PDIA4 P4HB	1.70e-06	8	110	3	12218052
Pubmed	Proteins of the PDI family: unpredicted non-ER locations and functions.	PDIA3 PDIA4 P4HB	1.70e-06	8	110	3	12384992
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA3 SEMA3C PLXNA1	1.70e-06	8	110	3	22368082
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	PLXNA3 KLF12 GGNBP2 TES ZNF235 JARID2 ZC2HC1A ZSCAN21 ZIC5 KLF5 KLF17 PLXNA1 ZNF513	1.74e-06	808	110	13	20412781
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF845 ZNF140 ZNF235 ZNF181 ZNF611 ZNF624 ZFP82	1.87e-06	181	110	7	37372979
Pubmed	PlexinA2 and semaphorin signaling during cardiac neural crest development.	PLXNA3 SEMA3C PLXNA1	2.55e-06	9	110	3	11688557
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PLXNA3 SEMA4B PELI3 PELI1 LRP1B PDIA3 ZBTB45 P4HB PRKCE PRKCH DNASE2 PLXNA1	3.60e-06	730	110	12	34857952
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS13 THSD7B ADAMTS7 ADAMTSL4 ADAMTSL2	4.18e-06	75	110	5	20637190
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA3 SEMA3C PLXNA1	6.63e-06	12	110	3	23991118
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	PLXNA3 SEMA3C PLXNA1	6.63e-06	12	110	3	25839327
Pubmed	ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase.	PDIA4 P4HB	9.91e-06	2	110	2	2295602
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	9.91e-06	2	110	2	11448776
Pubmed	Fbxw15/Fbxo12J is an F-box protein-encoding gene selectively expressed in oocytes of the mouse ovary.	FBXW12 P4HB	9.91e-06	2	110	2	18094359
Pubmed	P4HB and PDIA3 are associated with tumor progression and therapeutic outcome of diffuse gliomas.	PDIA3 P4HB	9.91e-06	2	110	2	29207176
Pubmed	ALS-linked protein disulfide isomerase variants cause motor dysfunction.	PDIA3 P4HB	9.91e-06	2	110	2	26869642
Pubmed	Functions of characteristic Cys-Gly-His-Cys (CGHC) and Gln-Glu-Asp-Leu (QEDL) motifs of microsomal ER-60 protease.	PDIA3 P4HB	9.91e-06	2	110	2	9399589
Pubmed	Characterization of large-scale genomic differences in the first complete human genome.	KLRC2 KLRC3	9.91e-06	2	110	2	37403156
Pubmed	Expressions and Functions of Krüppel Like Factor 5 and Tumor Necrosis Factor Receptor Superfamily Member 11a in Cervical Cancer Tissues and Cells.	TNFRSF11A KLF5	9.91e-06	2	110	2	28483017
Pubmed	KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression.	TNFRSF11A KLF5	9.91e-06	2	110	2	29146991
Pubmed	ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis.	ADAMTS13 ADAMTSL2	9.91e-06	2	110	2	17509843
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	9.91e-06	2	110	2	16041389
Pubmed	Cytosolic Pellino-1-Mediated K63-Linked Ubiquitination of IRF5 in M1 Macrophages Regulates Glucose Intolerance in Obesity.	PELI1 IRF5	9.91e-06	2	110	2	28746869
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA3 SEMA3C PLXNA1	1.67e-05	16	110	3	18489001
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	SEMA4B LAMA2 ADAMTS13 MMRN1 FAT2 ADGRF5 ADAMTSL4	1.85e-05	257	110	7	16335952
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA3 SEMA3C PLXNA1	2.03e-05	17	110	3	17626059
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXNA3 SEMA4B SEMA3C PLXNA1	2.28e-05	52	110	4	26633812
Pubmed	Embryonic expression of three mouse genes with homology to the Drosophila melanogaster prickle gene.	TES LMCD1	2.97e-05	3	110	2	14516664
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	2.97e-05	3	110	2	25637021
Pubmed	Regulation of perforin lysis: implications for protein disulfide isomerase proteins.	PDIA3 P4HB	2.97e-05	3	110	2	19147124
Pubmed	A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.	PRKCE PRKCH	2.97e-05	3	110	2	2266135
Pubmed	Differential modulation of Helicobacter pylori lipopolysaccharide-mediated TLR2 signaling by individual Pellino proteins.	PELI3 PELI1	2.97e-05	3	110	2	27302665
Pubmed	The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis.	PDIA3 P4HB	2.97e-05	3	110	2	26529254
Pubmed	Identification of plexin family molecules in mice.	PLXNA3 PLXNA1	2.97e-05	3	110	2	8806646
Pubmed	Spontaneous opening of the acetylcholine receptor channel in developing muscle cells from normal and dystrophic mice.	LAMA2 CHRNA1	2.97e-05	3	110	2	8568931
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA3 PLXNA1	2.97e-05	3	110	2	11241833
Pubmed	A PDI family network acts distinctly and coordinately with ERp29 to facilitate polyomavirus infection.	PDIA3 PDIA4	2.97e-05	3	110	2	21159867
Pubmed	RANKL and RANK: From Mammalian Physiology to Cancer Treatment.	TNFRSF11A BRCA1	2.97e-05	3	110	2	29241686
Pubmed	Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE2, PGD2, and HGF.	HGF PTGER2	2.97e-05	3	110	2	26875548
Pubmed	Protein kinase C epsilon signaling complexes include metabolism- and transcription/translation-related proteins: complimentary separation techniques with LC/MS/MS.	LDB3 PRKCE	2.97e-05	3	110	2	12169683
Pubmed	Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival.	PRKCE PRKCH	2.97e-05	3	110	2	23562764
Pubmed	Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.	PLXNA3 PLXNA1	2.97e-05	3	110	2	20138877
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANO9 KLF12 RIPOR2 FBXW12 OBSCN PDIA4 WDHD1 ZSCAN21 P4HB SIPA1L1 BTG4 QSOX2 ZFP82	3.96e-05	1084	110	13	11544199
Pubmed	Mapping wild-type and R345W fibulin-3 intracellular interactomes.	PDIA3 PDIA4 P4HB	4.54e-05	22	110	3	27777122
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PLXNA3 SEMA4B RASA3 TSNARE1 OBSCN IRF5 ZZEF1 PRAG1 MFSD12 ADAMTS7 STRN4 ZNRF1 PLXNA1	4.81e-05	1105	110	13	35748872
Pubmed	Dual Regulation of Spine-Specific and Synapse-to-Nucleus Signaling by PKCδ during Plasticity.	PRKCE PRKCH	5.92e-05	4	110	2	37277178
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA1	5.92e-05	4	110	2	11306810
Pubmed	Protein kinase C isoforms epsilon, eta, delta and zeta in murine adipocytes: expression, subcellular localization and tissue-specific regulation in insulin-resistant states.	PRKCE PRKCH	5.92e-05	4	110	2	8670164
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA1	5.92e-05	4	110	2	25518740
Pubmed	A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.	PRKCE PRKCH	5.92e-05	4	110	2	21602810
Pubmed	An interaction map of endoplasmic reticulum chaperones and foldases.	PDIA3 PDIA4	5.92e-05	4	110	2	22665516
Pubmed	Determination of cell adhesion sites of neuropilin-1.	PLXNA3 PLXNA1	5.92e-05	4	110	2	10725340
Pubmed	Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/egr-related zinc finger repressor.	KLF12 KLF5	5.92e-05	4	110	2	9858544
Pubmed	Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.	KLRC2 KLRC3	5.92e-05	4	110	2	8943374
Pubmed	Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.	RASA4 RASA4B	5.92e-05	4	110	2	16234249
Pubmed	And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance.	BRCA1 WDHD1	5.92e-05	4	110	2	27940552
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA3 PLXNA1	5.92e-05	4	110	2	8570614
Pubmed	KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.	PDIA3 P4HB	5.92e-05	4	110	2	30958660
Pubmed	Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.	RASA4 RASA4B	5.92e-05	4	110	2	21460216
Pubmed	Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases.	PELI3 PELI1	5.92e-05	4	110	2	16884718
Pubmed	Differentiation of nonbeating embryonic stem cells into beating cardiomyocytes is dependent on downregulation of PKC beta and zeta in concert with upregulation of PKC epsilon.	PRKCE PRKCH	5.92e-05	4	110	2	12648500
Pubmed	Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.	PELI3 PELI1	5.92e-05	4	110	2	19081057
Pubmed	RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.	TNFRSF11A BRCA1	5.92e-05	4	110	2	27322743
Pubmed	Unraveling the hidden role of a uORF-encoded peptide as a kinase inhibitor of PKCs.	PRKCE PRKCH	5.92e-05	4	110	2	34593629
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	SCRT2 KLF12 ZNF444 ZNF140 IRF5 ZBTB45 ZIC5 KLF5 KLF17	6.01e-05	544	110	9	28473536
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	PDIA3 PDIA4 PLXNA1	6.73e-05	25	110	3	17170699
Pubmed	PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria.	PDIA3 PDIA4 P4HB PRKCE PRKCH	7.48e-05	136	110	5	22304920
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	PLXNA3 SEMA3C PLXNA1	9.52e-05	28	110	3	18617019
Pubmed	Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.	PLXNA3 PLXNA1	9.85e-05	5	110	2	25313870
Pubmed	The genomic organization of NKG2C, E, F, and D receptor genes in the human natural killer gene complex.	KLRC2 KLRC3	9.85e-05	5	110	2	9683661
Pubmed	Protein kinase C(mu) regulation of the JNK pathway is triggered via phosphoinositide-dependent kinase 1 and protein kinase C(epsilon).	PRKCE PRKCH	9.85e-05	5	110	2	12223477
Pubmed	ERp57 functions as a subunit of specific complexes formed with the ER lectins calreticulin and calnexin.	PDIA3 P4HB	9.85e-05	5	110	2	10436013
Pubmed	Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.	ADAMTSL4 ADAMTSL2	9.85e-05	5	110	2	29758265
Pubmed	Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis.	PELI1 IRF5	9.85e-05	5	110	2	34504806
Pubmed	A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.	KLF12 KLF5	9.85e-05	5	110	2	20101243
Pubmed	Progress in targeting HIV-1 entry.	PDIA3 PDIA4	9.85e-05	5	110	2	16182193
Pubmed	Transient covalent interactions of newly synthesized thyroglobulin with oxidoreductases of the endoplasmic reticulum.	PDIA3 PDIA4	9.85e-05	5	110	2	24599957
Pubmed	Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum.	PDIA3 P4HB	9.85e-05	5	110	2	21057456
Pubmed	RANKL/RANK control Brca1 mutation- .	TNFRSF11A BRCA1	9.85e-05	5	110	2	27241552
Pubmed	Development and function of CD94-deficient natural killer cells.	KLRC2 KLRC3	9.85e-05	5	110	2	21151939
Pubmed	Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.	PDIA3 PDIA4 P4HB	1.06e-04	29	110	3	12643545
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	SEMA3C LAMA2 SVEP1 ADAMTS7 HPR ADAMTSL4	1.43e-04	248	110	6	24006456
Pubmed	Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.	PDIA3 PDIA4	1.47e-04	6	110	2	19995400
Pubmed	Protein kinase C isoform expression and activity in the mouse heart.	PRKCE PRKCH	1.47e-04	6	110	2	11668067
Pubmed	The disulfide isomerase ERp72 supports arterial thrombosis in mice.	PDIA3 PDIA4	1.47e-04	6	110	2	28576878
Pubmed	Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta.	PRKCE PRKCH	1.47e-04	6	110	2	8621384
Pubmed	Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.	PRKCE PRKCH	1.47e-04	6	110	2	15632189
Pubmed	Shaking the family tree: identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors.	KLF12 KLF5	1.47e-04	6	110	2	23134681
Pubmed	Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis.	SEMA3C PLXNA1	1.47e-04	6	110	2	11442635
Pubmed	The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities.	PELI3 PELI1	1.47e-04	6	110	2	25027698
Cytoband	12p13	AICDA CD27 KLRC2 KLRC3	1.77e-05	64	110	4	12p13
Cytoband	6p12.3	OPN5 ADGRF5 TDRD6	9.02e-05	36	110	3	6p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF132 ZNF444 ZNF845 ZNF235 ZNF181 ZBTB45 ZNF256 STRN4 ZNF611 ZFP82	6.03e-04	1192	110	10	chr19q13
Cytoband	19q13.43	ZNF444 ZBTB45 ZNF256	1.23e-03	87	110	3	19q13.43
Cytoband	20p13	SCRT2 RBCK1 DEFB132	1.93e-03	102	110	3	20p13
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	ZSCAN25 ZSCAN21 RASA4 RASA4B	1.96e-03	219	110	4	chr7q22
Cytoband	7q22.1	ZSCAN25 ZSCAN21 RASA4B	2.59e-03	113	110	3	7q22.1
Cytoband	4q24	CISD2 PAPSS1	3.04e-03	34	110	2	4q24
Cytoband	Ensembl 112 genes in cytogenetic band chr20p13	SCRT2 RBCK1 DEFB132	3.29e-03	123	110	3	chr20p13
Cytoband	Ensembl 112 genes in cytogenetic band chr6p12	OPN5 ADGRF5 TDRD6	4.91e-03	142	110	3	chr6p12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	SCRT2 ZNF132 KLF12 ZNF444 ZNF845 ZNF140 ZSCAN25 ZNF235 ZNF181 ZBTB45 ZSCAN21 ZIC5 KLF5 ZNF256 ZNF611 ZNF624 KLF17 ZNF682 ZFP82 ZNF572 ZNF513	1.43e-11	718	86	21	28
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA3 RASA4 RASA4B	1.22e-05	10	86	3	830
GeneFamily	Pellino E3 ubiquitin protein ligases	PELI3 PELI1	6.69e-05	3	86	2	676
GeneFamily	Zinc fingers C2H2-type\|Kruppel like factors	KLF12 KLF5 KLF17	8.05e-05	18	86	3	624
GeneFamily	Protein disulfide isomerases	PDIA3 PDIA4 P4HB	1.30e-04	21	86	3	692
GeneFamily	LIM domain containing	TES LMCD1 LDB3 FHL3	1.78e-04	59	86	4	1218
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF11A CD27 EDA2R	3.47e-04	29	86	3	782
GeneFamily	ADAMTS like	ADAMTSL4 ADAMTSL2	4.62e-04	7	86	2	947
GeneFamily	Plexins	PLXNA3 PLXNA1	7.88e-04	9	86	2	683
GeneFamily	C2 domain containing protein kinases	PRKCE PRKCH	9.82e-04	10	86	2	835
GeneFamily	CD molecules\|C-type lectin domain family\|Killer cell lectin like receptors	KLRC2 KLRC3	1.43e-03	12	86	2	621
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS13 ADAMTS7	3.63e-03	19	86	2	50
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA4B SEMA3C	4.02e-03	20	86	2	736
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPRY1 PTGER2 DNAI3 FAT2 PRKCH KLRC2 KLRC3 ZFP82	9.93e-09	169	110	8	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	RIPOR2 THSD7B PRAG1 STAB1 MMRN1 PRKCE PRKCH ADGRF5	3.15e-08	196	110	8	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C RASA3 LMCD1 LAMA2 SVEP1 LDB3 ADAMTSL2	3.28e-08	197	110	8	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF845 LMCD1 PELI1 STAB1 ZBTB45 ZNRF1 QSOX2	4.10e-07	186	110	7	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B RASA3 PDIA3 STAB1 PDIA4 P4HB FHL3	4.56e-07	189	110	7	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B RASA3 PDIA3 STAB1 PDIA4 P4HB FHL3	4.56e-07	189	110	7	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B RASA3 PDIA3 STAB1 PDIA4 P4HB FHL3	4.56e-07	189	110	7	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4B RASA3 PDIA3 STAB1 PDIA4 P4HB FHL3	4.56e-07	189	110	7	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C RASA3 LMCD1 LAMA2 SVEP1 ADAMTSL2	6.24e-07	198	110	7	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 SLCO6A1 SVEP1 FAT2 KLF17 ADAMTSL2	2.00e-06	150	110	6	7a9d6a7ff8000e9a061e1b586e4c258cc91a2a09
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 SLCO6A1 SVEP1 FAT2 KLF17 ADAMTSL2	2.00e-06	150	110	6	e5b843cb2bc847f6cab4cbec0a2a6a72fac50fee
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HGF AICDA PELI3 IRF5 PRKCE RASA4B	2.60e-06	157	110	6	f896997490bb2eec598c6581f161220e70f9a991
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HGF AICDA PELI3 IRF5 PRKCE RASA4B	2.60e-06	157	110	6	14a8516346a89a89f1119b744625bd9844a74a03
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ADAMTS13 TNFRSF11A PDIA3 PRKCH KLRC3 RSPH10B	4.41e-06	172	110	6	68fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCell	Control-Lymphoid-ILC_A\|Lymphoid / Disease state, Lineage and Cell class	SPRY1 PNMT TNFRSF11A MMRN1 SIPA1L1 KLRC2	6.70e-06	185	110	6	520795866d44def5be3910ce8e728045c716a24d
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	KLF12 RIPOR2 RASA3 PRKCH KLRC2 KLRC3	6.70e-06	185	110	6	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZNF845 LMCD1 PELI1 STAB1 ZBTB45 QSOX2	7.12e-06	187	110	6	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	KLF12 RIPOR2 RASA3 PRKCH KLRC2 KLRC3	7.57e-06	189	110	6	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C RASA3 LMCD1 LAMA2 SVEP1	7.80e-06	190	110	6	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLF12 RIPOR2 RASA3 PTGER2 PRKCH KLRC3	7.80e-06	190	110	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C RASA3 LMCD1 LAMA2 SVEP1	7.80e-06	190	110	6	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMCD1 TNFRSF11A STAB1 MMRN1 RASA4 ADGRF5	8.28e-06	192	110	6	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMCD1 TNFRSF11A STAB1 MMRN1 RASA4 ADGRF5	8.28e-06	192	110	6	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF845 TES ZNF235 PTGER2 PRKCH KLRC3	8.78e-06	194	110	6	6be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEMA3C LMCD1 PRAG1 BRCA1 WDHD1 ADAMTSL2	8.78e-06	194	110	6	590a9d4f054e6a3685daf752c9354650fcc7d18a
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPRY1 SEMA3C PNMT LMCD1 PTGER2 KCTD16	8.78e-06	194	110	6	7bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPRY1 SEMA3C PNMT LMCD1 PTGER2 KCTD16	8.78e-06	194	110	6	19e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMCD1 TNFRSF11A STAB1 RASA4 PRKCH ADGRF5	9.04e-06	195	110	6	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	15-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	SEMA3C LMCD1 PTGER2 PRAG1 FHL3 ADAMTSL2	9.31e-06	196	110	6	0e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C LMCD1 LAMA2 SVEP1 ADAMTSL2	9.58e-06	197	110	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HGF SEMA3C LMCD1 LAMA2 SVEP1 ADAMTSL2	9.58e-06	197	110	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF LMCD1 LAMA2 SVEP1 KCTD16 ADAMTSL2	9.58e-06	197	110	6	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	HGF SPRY1 LMCD1 SVEP1 KCTD16 ADAMTSL2	1.01e-05	199	110	6	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPRY1 SEMA3C LMCD1 LAMA2 ADAMTS13 ZC2HC1A	1.01e-05	199	110	6	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	distal-Hematologic-Natural_Killer-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RIPOR2 RASA3 PTGER2 PRKCH KLRC2 KLRC3	1.01e-05	199	110	6	af6516ac364202c5024694b92df903a04caea823
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm\|Leuk-UTI / Disease, condition lineage and cell class	SPRY1 PTGER2 DNAI3 CD27 RASA4B PRKCH	1.01e-05	199	110	6	6a1d84f61e1efaab541910926d6911122372659f
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	HGF RASA3 LMCD1 LAMA2 SVEP1 ADAMTSL2	1.01e-05	199	110	6	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF LMCD1 LAMA2 SVEP1 KCTD16 ADAMTSL2	1.04e-05	200	110	6	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	distal-3-Hematologic-Natural_Killer\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RIPOR2 RASA3 PTGER2 PRKCH KLRC2 KLRC3	1.04e-05	200	110	6	ea11ace5d540c02f23242e48e4d0d7d54999af0e
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	SPRY1 SEMA3C LMCD1 LAMA2 PTGER2 LDB3	1.04e-05	200	110	6	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SPRY1 SEMA3C LMCD1 LAMA2 ADAMTS13 ZC2HC1A	1.04e-05	200	110	6	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HGF LMCD1 LAMA2 SVEP1 KCTD16 ADAMTSL2	1.04e-05	200	110	6	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	SPRY1 SEMA3C LMCD1 LAMA2 LDB3 ZC2HC1A	1.04e-05	200	110	6	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 SVEP1 ADAMTS7 DEFB132 ADAMTSL2	2.93e-05	144	110	5	cf9f049ab6cd80521598124f057c2debdde24788
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 SVEP1 ADAMTS7 DEFB132 ADAMTSL2	2.93e-05	144	110	5	41eaeca54b3c39de417597267cbdb1f195dd885a
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|368C / Donor, Lineage, Cell class and subclass (all cells)	ANO9 ZNF235 WDHD1 ZNF256 KLRC2	3.23e-05	147	110	5	3ed5b020ce1f1277917d79ef1f7da53fa474e8db
ToppCell	URO-Lymphocyte-T_NK-NK_CD56bright\|URO / Disease, Lineage and Cell Type	PNMT TNFRSF11A MMRN1 KLRC2 KLRC3	3.23e-05	147	110	5	a6ca90e8dc37a016572ff68f34ab227b020eef70
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C PRAG1 PRKCH KLRC2 KLRC3	4.16e-05	155	110	5	c58a5fb8d853f12204e961d633e83452eb12a659
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C PRAG1 PRKCH KLRC2 KLRC3	4.16e-05	155	110	5	9cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SEMA3C LMCD1 PTGER2 PRAG1 ADAMTSL2	4.42e-05	157	110	5	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	Leuk-UTI-Lymphocyte-T_NK-gdT\|Leuk-UTI / Disease, Lineage and Cell Type	CD27 PRKCH TDRD6 KLRC2 KLRC3	4.56e-05	158	110	5	c4b0af25608cee3d0d2b0193f5ff45d9dc87078b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 LAMA2 LRP1B SVEP1 TDRD6	4.84e-05	160	110	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	PBMC-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	HGF AICDA PELI3 RASA4B PLXNA1	4.84e-05	160	110	5	4dac64e58d9366c399f3d830848ccb720d400be7
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUC19 LAMA2 LRP1B SVEP1 TDRD6	4.84e-05	160	110	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 SVEP1 CD27 DNASE2 ADAMTSL2	5.13e-05	162	110	5	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SEMA3C THSD7B LRP1B ZNF181 RASA4	5.29e-05	163	110	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SPRY1 SEMA3C PTGER2 ADAMTS7 KCTD16	5.29e-05	163	110	5	bba830a302919c8b33f914a8839877fc21dd28a0
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV5/7_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPRY1 PTGER2 PRKCH KLRC2 KLRC3	5.60e-05	165	110	5	207f9ca8839f54710e2112986def4bc7b0ef1a28
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PTGER2 ADAMTS7 RTL1 ADAMTSL2	5.88e-05	85	110	4	bb9555652e93620d5aeeb71e915b3978a437407d
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PTGER2 ADAMTS7 RTL1 ADAMTSL2	5.88e-05	85	110	4	f7935c3206310adafdecb75149c3b06c38e7780c
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	PTGER2 ADAMTS7 RTL1 ADAMTSL2	5.88e-05	85	110	4	43f6911b032718d8ba75fb7bba5f9b536a4b3260
ToppCell	facs-Heart-LA-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 TES CD27 KLRC2 KLRC3	6.10e-05	168	110	5	16c3313c4186fa327d71215f8eebc31fc12ff1c0
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 TES CD27 KLRC2 KLRC3	6.10e-05	168	110	5	24d1e0a05cda09ee3b80208d75cb2b601023f3bf
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 TES CD27 KLRC2 KLRC3	6.10e-05	168	110	5	b952af95a68888adedd03b1b60836d18524611ab
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TES ZSCAN25 PRAG1 BRCA1 CD27	6.63e-05	171	110	5	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A FAM3B TNFRSF11A BRCA1 RASA4	6.82e-05	172	110	5	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A FAM3B TNFRSF11A BRCA1 RASA4	6.82e-05	172	110	5	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	10x5'-blood-Mast-Mast_cells\|blood / Manually curated celltypes from each tissue	HGF SEMA3C PNMT ZC2HC1A KLF5	7.20e-05	174	110	5	a5838821bba2be790d32331ff529d466e9974268
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY1 PTGER2 CD27 ZNRF1 PRKCH	7.20e-05	174	110	5	919fc124affc69acfd8f575f2c372674f3d2625e
ToppCell	10x5'-blood-Mast\|blood / Manually curated celltypes from each tissue	HGF SEMA3C PNMT ZC2HC1A KLF5	7.20e-05	174	110	5	3a8a253213b207e3ff56f94a74996b8d9ad47aa1
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM3B TNFRSF11A ANKRD33 KLF5 DMBT1	7.40e-05	175	110	5	0431897d7fcc9cefb516cd36987cf18b7f19a26a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPRY1 SEMA3C LAMA2 PRAG1 ADGRF5	7.60e-05	176	110	5	212e643c50c68462d4b016428ab30eeb7868ef40
ToppCell	Control-Lymphoid-ILC_B\|Control / Disease state, Lineage and Cell class	SPRY1 RIPOR2 PNMT TNFRSF11A KLRC2	7.81e-05	177	110	5	3d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGF LAMA2 SVEP1 HPR ADAMTSL2	8.02e-05	178	110	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	LMCD1 LAMA2 SVEP1 KCTD16 ADAMTSL2	8.23e-05	179	110	5	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO9 TNFRSF11A MMRN1 PRKCH ADGRF5	8.23e-05	179	110	5	dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCell	10x5'v1-week_12-13-Lymphocytic_T-T_NK-CD8_T_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KLF12 RIPOR2 CD27 PRKCH KLRC3	8.45e-05	180	110	5	5273aa2b939b5c640d708d6ca1812550dff5ec0f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO9 SEMA3C FAM3B KLF5 DMBT1	8.45e-05	180	110	5	8d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PELI1 PTGER2 CD27 ZNRF1 PRKCH	8.45e-05	180	110	5	978728c89497d26287f73974fb738ad9fde61415
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	STAB1 MMRN1 EYS PRKCH ADGRF5	8.45e-05	180	110	5	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	(2)_NK/T-(230)_CD4+/CD25+_Reg_T_cell\|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)	LMCD1 PELI1 ZC2HC1A CD27 ZNRF1	8.67e-05	181	110	5	ad14c7111d4fb924afd233cb114447f195373a7c
ToppCell	facs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY1 PTGER2 CD27 ZNRF1 PRKCH	8.90e-05	182	110	5	da3e9093cba791c7c282eb044656046252a32789
ToppCell	ILEUM-inflamed-(5)_IgA_plasma_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CISD2 PELI1 PDIA4 P4HB CD27	9.13e-05	183	110	5	a113558ca4220bac31f9336033dff82a618d9258
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPRY1 STAB1 MMRN1 RASA4 RASA4B	9.13e-05	183	110	5	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPRY1 PELI1 PTGER2 CD27 PRKCH	9.37e-05	184	110	5	8c23945bafe8926f25836bc208115edd5214a2b0
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MUC19 THSD7B EYS PRKCH ADGRF5	9.37e-05	184	110	5	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KLF12 SEMA3C LMCD1 LAMA2 ADAMTS13	9.61e-05	185	110	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	KLF12 RIPOR2 RASA3 PRKCH KLRC3	9.61e-05	185	110	5	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA4B RAET1G FAM3B FAT2 KLF5	9.61e-05	185	110	5	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF PNMT TNFRSF11A MMRN1 ZIC5	9.61e-05	185	110	5	241ea1e178fffef9e7df971de739e794332d5173
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LMCD1 STAB1 MMRN1 PRKCH ADGRF5	9.61e-05	185	110	5	59acaf025353405948dc34ccccf37ec5c08ea903
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TES PELI1 CD27 ZNRF1 PRKCH	9.61e-05	185	110	5	39f2b7a35253968f6d744c10ece1478a05cf24da
ToppCell	10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD4_T_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ANO9 RIPOR2 CD27 PRKCH KLRC3	9.61e-05	185	110	5	32f43ddc8a899827924834546db33928e353271b
ToppCell	droplet-Bladder-nan-24m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMCD1 STAB1 MMRN1 LDB3 ADGRF5	9.61e-05	185	110	5	90caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNFRSF11A TBC1D8B STAB1 TDRD6 ADAMTSL4	9.86e-05	186	110	5	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNFRSF11A TBC1D8B STAB1 TDRD6 ADAMTSL4	9.86e-05	186	110	5	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Tregs\|bone_marrow / Manually curated celltypes from each tissue	LMCD1 PELI1 ZC2HC1A CD27 ZNRF1	1.01e-04	187	110	5	bda716a64262325e6e68b281caf131f1840fd298
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	LMCD1 MUC19 FAM3B TBC1D8B P4HB	1.01e-04	187	110	5	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEMA3C LMCD1 PRAG1 FHL3 ADAMTSL2	1.01e-04	187	110	5	387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HGF RASA3 LMCD1 SVEP1 ADAMTSL2	1.01e-04	187	110	5	76bfe8c42430a230a8bdf299575c444fb7780f24
Computational	Neighborhood of RAB7L1	TES PTGER2 PRKCH KLRC3	3.18e-05	33	60	4	GNF2_RAB7L1
Computational	Oxidoreductases.	PDIA3 PDIA4 P4HB	7.17e-05	15	60	3	MODULE_519
Disease	aspartate aminotransferase measurement	PDHB OBSCN MUC19 THSD7B NDUFA8 PRAG1 MFSD12 BRCA1 HPR STRN4 KLRC2 KLRC3	8.30e-05	904	104	12	EFO_0004736
Disease	non-high density lipoprotein cholesterol measurement	PLXNA3 KLF12 GGNBP2 PDHB ZNF235 RBCK1 POM121 HPR PRKCE QSOX2	2.16e-04	713	104	10	EFO_0005689
Disease	helping behavior measurement	SCRT2 KLF12	3.40e-04	8	104	2	EFO_0008538
Disease	SPINOCEREBELLAR ATAXIA 17	PDIA3 P4HB	4.36e-04	9	104	2	C1846707
Disease	immunoglobulin isotype switching measurement	PDHB KLRC2 KLRC3	5.07e-04	44	104	3	EFO_0010128
Disease	alkaline phosphatase measurement	SEMA4B KLF12 RIPOR2 ZCCHC10 IRF5 ADAMTS13 TNFRSF11A PRAG1 POM121 DMBT1 ADAMTSL2	9.14e-04	1015	104	11	EFO_0004533
Disease	Myasthenia gravis	TNFRSF11A CHRNA1	9.36e-04	13	104	2	EFO_0004991
Disease	tyrosine-protein kinase receptor Tie-1, soluble measurement	ADAMTS13 ADAMTSL2	9.36e-04	13	104	2	EFO_0008312
Disease	CD209 antigen measurement	ADAMTS13 ADAMTSL2	1.09e-03	14	104	2	EFO_0008077
Disease	serum albumin measurement	HGF SEMA3C RASA3 ZZEF1 SVEP1 HPR OPN5 QSOX2	1.19e-03	592	104	8	EFO_0004535
Disease	myopia (is_implicated_in)	HGF LAMA2	1.43e-03	16	104	2	DOID:11830 (is_implicated_in)
Disease	Hereditary hearing loss and deafness	HGF RIPOR2 CISD2 PDHB	1.80e-03	146	104	4	cv:C0236038
Disease	late-onset myasthenia gravis	TNFRSF11A CHRNA1	1.81e-03	18	104	2	EFO_1001490
Disease	glaucoma	SEMA3C RIPOR2 TES LRP1B	2.19e-03	154	104	4	MONDO_0005041
Disease	energy expenditure measurement	KLF12 THSD7B	2.24e-03	20	104	2	EFO_0008005
Disease	alpha-tocopherol measurement	HGF PRKCE	2.24e-03	20	104	2	EFO_0007898
Disease	Nonsyndromic genetic hearing loss	HGF RIPOR2 CISD2	2.48e-03	76	104	3	cv:C5680182
Disease	liver cirrhosis (is_marker_for)	IRF5 ADAMTS13 PDIA3	3.08e-03	82	104	3	DOID:5082 (is_marker_for)
Disease	CFTR mutation carrier status	TMEM229A THSD7B	3.50e-03	25	104	2	EFO_0021794

Protein segments in the cluster

Peptide	Gene	Start	Entry
AYWKRVGHSACSASC	ADAMTSL4	666	Q6UY14
SCPERHYWAQGKLCC	CD27	26	P26842
FTSWSPCYDCARHVA	AICDA	81	Q9GZX7
CVEYLVPWVTHKCRS	ANO9	491	A1A5B4
SCCAPKRYTSGHWSL	DNAI3	711	Q8IWG1
TPGYCRTCCHWGETA	DEFB132	31	Q7Z7B7
PCLIADCTYRWHVGT	ADAMTS13	1066	Q76LX8
HYGPWTKCTVTCGRG	ADAMTS7	826	Q9UKP4
SYHPGVFRGDKWSCC	RASA4	681	O43374
TPGCRLGALYWACVH	ANKRD33	91	Q7Z3H0
SYHPGVFRGDKWSCC	RASA4B	681	C9J798
YLSGHWLCCRAPSDS	RASA3	691	Q14644
CGHCIGYAPTWRALA	QSOX2	91	Q6ZRP7
SRGWKHSVTYSCCPD	CHRNA1	201	P02708
KCSTQPVSYIGHWCN	RSPH10B	171	P0C881
KCSTQPVSYIGHWCN	RSPH10B2	171	B2RC85
CFAAWYGHCPGLKVV	PDHB	161	P11177
EKGDLRCHCWPSYSG	LRP1B	4231	Q9NZR2
RCHCWPSYSGERCEV	LRP1B	4236	Q9NZR2
SEAWSKTYSCHCQPP	EYS	191	Q5T1H1
MGRSWHPEEFTCAYC	LDB3	566	O75112
FYREPSRWSPSHCDC	KCTD16	276	Q68DU8
YCRLNDHKRPICSGW	GGNBP2	676	Q9H3C7
HKIVTSLDWRCCPGY	MMRN1	261	Q13201
CITHYEGSTCPKWKA	HPR	251	P00739
AFSYHCKTPDCKGWC	RBCK1	366	Q9BYM8
TYCSHCRDFIWGVIG	PRKCE	181	Q02156
WEEGGRHPYLRSCCH	FBXW12	406	Q6X9E4
VNGSFPCHWCKYRHV	PLXNA1	671	Q9UIW2
SCVGSPYPCHWCKYR	PLXNA3	646	P51805
KCSWTHGAGYVCKCP	FAT2	3961	Q9NYQ8
WHYEPCGTVTAKTCK	MUC19	1551	Q7Z5P9
YCPGTWCFIRHGRTA	PTGER2	181	P43116
GKPFTIISCFCHRWV	OPN5	86	Q6U736
YRWKLSSHEPCSATC	ADAMTSL2	566	Q86TH1
SGAKCTECSRGHWNY	LAMA2	1086	P24043
TECSRGHWNYPRCNL	LAMA2	1091	P24043
PHTRWEYCAIKTCAD	HGF	276	P14210
QCKVFWSGPCASAHD	IRF5	341	Q13568
VEFYAPWCGHCKALA	P4HB	46	P07237
QKCDHWTPCPSDTYA	FAM3B	61	P58499
CKGTCSGFEPHSWRK	LMCD1	31	Q9NZU5
SGFEPHSWRKICKSC	LMCD1	36	Q9NZU5
DGAPWCGRHYCESLR	LMCD1	291	Q9NZU5
CVLSSVAAPVKWCYG	OBSCN	3206	Q5VST9
CLGVLPTVCWNGYHK	POM121	241	Q96HA1
RCARQWGTTCKNHPY	PAPSS1	351	O43252
CPSLDDRWYMHSCSG	BRCA1	1501	P38398
YRDQPWHRECLVCTG	FHL3	176	Q13643
WPHSACTYGQTLLCV	DNASE2	146	O00115
HTGEKPYKCTWEGCT	KLF12	341	Q9Y4X4
KHTGERPYSCNWESC	KLF17	306	Q5JT82
LWCSRCFFSHGPKGS	FAM215A	61	Q9Y5M1
VRCSGHESYLWSCPH	DMBT1	301	Q9UGM3
VRCSGNESYLWSCPH	DMBT1	561	Q9UGM3
DVRCSGHESYLWSCP	DMBT1	1446	Q9UGM3
VRCSGHESYLWSCPH	DMBT1	1576	Q9UGM3
CCARYGPRKAWHLVG	MFSD12	86	Q6NUT3
RHCAEPFTEYWTCID	NDUFA8	76	P51970
PCGHVCSEKTTAYWS	PELI1	366	Q96FA3
LHTGADCIWYCIPAE	JARID2	941	Q92833
VDWIKGRCTFHSPYC	RTL1	516	A6NKG5
GYDKLWHPACFVCST	TES	256	Q9UGI8
RHKCGVCGKAFSRPW	SCRT2	211	Q9NQ03
PCASCGLDGHWYRAL	TDRD6	316	O60522
LARDPYCAWDGHSCS	SEMA3C	526	Q99985
LGLRTCGACSWDYSH	TMEM229A	326	B2RXF0
ARHCGHCPEEWITYS	KLRC2	111	P26717
APCGHVCSEKTARYW	PELI3	416	Q8N2H9
WCGHCKRLAPEYEAA	PDIA3	56	P30101
PYCAWSGSSCKHVSL	SEMA4B	541	Q9NPR2
SVRPWTCPKCFAHYD	SIPA1L1	321	O43166
RDVNKCGHTGRCWIY	SLCO6A1	646	Q86UG4
ARHCGHCPEEWITYS	KLRC3	111	Q07444
AWHSRYKFCPTCGNA	NUDT12	276	Q9BQG2
TVLLEFYAPWCGHCK	PDIA4	81	P13667
WSGSESYCRVRTCPH	SVEP1	426	Q4LDE5
FWTKCCSPVGVYHSP	RIPOR2	816	Q9Y4F9
WHSDCPSKGQAFRCI	BTG4	46	Q9NY30
SCETGYGWPRERCLH	ADGRF5	121	Q8IZF2
CWRSKTFPACDGSHN	CISD2	101	Q8N5K1
WRTHSGEKPYKCEEC	ZNF845	626	Q96IR2
HTGEKPYRCSECWKT	ZNF572	406	Q7Z3I7
YSQHACLIEGKGECW	PNMT	126	P11086
PFRCATCAYTTGHWD	ZNF513	471	Q8N8E2
GITHIYSPQVWACCL	STIL	266	Q15468
CHWRVHTGERPYECS	ZNF132	616	P52740
WRTHTGEKPYTCKEC	ZNF624	771	Q9P2J8
THSGARPFACWECGK	ZNF444	271	Q8N0Y2
SGEKPHQCAVCWRSF	ZBTB45	426	Q96K62
CARCWTEYGIRHFPC	TSNARE1	31	Q96NA8
EKPYWCHHCGKTFCS	ZSCAN21	441	Q9Y5A6
FLSCYWCLGCPVLKH	TBC1D8B	811	Q0IIM8
EKGYAICGLAWHPTC	WDHD1	271	O75717
ICGLAWHPTCGRISY	WDHD1	276	O75717
THLGKRPYVCSECWK	ZSCAN25	396	Q6NSZ9
HTGERPYECSECWKS	ZNF256	541	Q9Y2P7
PYKCEECGKAFHWCS	ZNF682	256	O95780
ECGKAFHWCSPFVRH	ZNF682	261	O95780
SWCRTGLADPHSLCY	RAET1G	21	Q6H3X3
VQKACCPGYWGSRCH	STAB1	96	Q9NY15
CYDWIHRPGCRCKNS	SPRY1	286	O43609
ACSDFVEHIWKPGSC	PRAG1	16	Q86YV5
QKCLEFGHWTYECTG	ZCCHC10	46	Q8TBK6
EAARAWCHCTSSQYP	nan	151	Q8NA96
HECGTKYPVEWAKFC	ZC2HC1A	301	Q96GY0
RIHTGEKPYECKECW	ZFP82	386	Q8N141
LYECDECGKVFTWHA	ZNF140	356	P52738
ISCDGCDEIAPWHRY	ZZEF1	1781	O43149
KPYRCKVCDTAFTWH	ZNF611	396	Q8N823
CYSGGADACIHSWKI	STRN4	506	Q9NRL3
ETRPCTGGKCYHYTW	THSD7B	1421	Q9C0I4
CTACPPRRYKSSWGH	EDA2R	41	Q9HAV5
SVRTGKKRYWCHECG	ZNF235	311	Q14590
PCLCIYHKSCIDSWF	ZNRF1	201	Q8ND25
WRIHTGEKPYECREC	ZNF181	256	Q2M3W8
STTPRRCACTAGYHW	TNFRSF11A	106	Q9Y6Q6
SSHVCFWEDCPREGK	ZIC5	456	Q96T25
THTGEKPYKCTWEGC	KLF5	396	Q13887
QPTYCSHCREFIWGV	PRKCH	181	P24723