| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | GTPase regulator activity | 8.15e-05 | 507 | 42 | 7 | GO:0030695 | |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | 8.15e-05 | 507 | 42 | 7 | GO:0060589 | |
| GeneOntologyBiologicalProcess | regulation of transcription by RNA polymerase III | 3.22e-05 | 32 | 40 | 3 | GO:0006359 | |
| GeneOntologyCellularComponent | transcription elongation factor complex | 1.55e-04 | 56 | 39 | 3 | GO:0008023 | |
| GeneOntologyCellularComponent | cell division site | 4.47e-04 | 80 | 39 | 3 | GO:0032153 | |
| GeneOntologyCellularComponent | Golgi medial cisterna | 8.37e-04 | 23 | 39 | 2 | GO:0005797 | |
| Domain | Gonadal | 4.70e-06 | 2 | 41 | 2 | IPR010849 | |
| Domain | DGCR6 | 4.70e-06 | 2 | 41 | 2 | PF07324 | |
| Domain | IQ | 1.75e-05 | 71 | 41 | 4 | PF00612 | |
| Domain | IQ_motif_EF-hand-BS | 4.45e-05 | 90 | 41 | 4 | IPR000048 | |
| Domain | IQ | 5.07e-05 | 93 | 41 | 4 | PS50096 | |
| Domain | IQ | 7.44e-04 | 81 | 41 | 3 | SM00015 | |
| Domain | ZnF_U1 | 1.84e-03 | 29 | 41 | 2 | SM00451 | |
| Domain | Znf_U1 | 1.84e-03 | 29 | 41 | 2 | IPR003604 | |
| Domain | Quinoprotein_ADH-like_supfam | 6.04e-03 | 53 | 41 | 2 | IPR011047 | |
| Domain | Ca/CaM-dep_Ca-dep_prot_Kinase | 1.01e-02 | 69 | 41 | 2 | IPR020636 | |
| Domain | EF_HAND_1 | 1.01e-02 | 204 | 41 | 3 | PS00018 | |
| Pubmed | 2.86e-08 | 251 | 44 | 7 | 28077445 | ||
| Pubmed | 4.84e-07 | 233 | 44 | 6 | 37704626 | ||
| Pubmed | Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells. | 1.50e-06 | 283 | 44 | 6 | 30585729 | |
| Pubmed | NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling. | 1.56e-06 | 2 | 44 | 2 | 16488889 | |
| Pubmed | 1.56e-06 | 2 | 44 | 2 | 15821931 | ||
| Pubmed | 1.56e-06 | 2 | 44 | 2 | 22832905 | ||
| Pubmed | 1.56e-06 | 2 | 44 | 2 | 9605865 | ||
| Pubmed | 1.56e-06 | 2 | 44 | 2 | 11157784 | ||
| Pubmed | 4.26e-06 | 529 | 44 | 7 | 14621295 | ||
| Pubmed | 4.31e-06 | 340 | 44 | 6 | 29478914 | ||
| Pubmed | Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids. | 4.69e-06 | 3 | 44 | 2 | 8529672 | |
| Pubmed | Integration of cytogenetic with recombinational and physical maps of mouse chromosome 16. | 1.56e-05 | 5 | 44 | 2 | 10395793 | |
| Pubmed | Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma. | 2.31e-05 | 1257 | 44 | 9 | 36526897 | |
| Pubmed | 2.46e-05 | 963 | 44 | 8 | 28671696 | ||
| Pubmed | 3.49e-05 | 733 | 44 | 7 | 34672954 | ||
| Pubmed | 3.54e-05 | 1014 | 44 | 8 | 32416067 | ||
| Pubmed | MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons. | 5.60e-05 | 1082 | 44 | 8 | 38697112 | |
| Pubmed | 6.74e-05 | 1442 | 44 | 9 | 35575683 | ||
| Pubmed | 7.51e-05 | 177 | 44 | 4 | 26206133 | ||
| Pubmed | Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event. | 8.36e-05 | 182 | 44 | 4 | 26527279 | |
| Pubmed | FAM184B CEP131 SF3B1 GOLGA5 ARGLU1 SUPT6H NUCB2 UTP14A SUPT16H | 8.52e-05 | 1487 | 44 | 9 | 33957083 | |
| Pubmed | MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development. | 8.78e-05 | 358 | 44 | 5 | 32460013 | |
| Pubmed | SR protein kinases promote splicing of nonconsensus introns. | 9.13e-05 | 361 | 44 | 5 | 26167880 | |
| Pubmed | 1.02e-04 | 12 | 44 | 2 | 9383280 | ||
| Pubmed | TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression. | 1.02e-04 | 12 | 44 | 2 | 30479348 | |
| Pubmed | Transcription factor Foxp3 and its protein partners form a complex regulatory network. | 1.02e-04 | 370 | 44 | 5 | 22922362 | |
| Pubmed | 1.21e-04 | 13 | 44 | 2 | 11700028 | ||
| Pubmed | TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions. | 1.47e-04 | 922 | 44 | 7 | 27609421 | |
| Pubmed | 1.50e-04 | 1247 | 44 | 8 | 27684187 | ||
| Pubmed | LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. | 1.63e-04 | 15 | 44 | 2 | 14976552 | |
| Pubmed | 1.65e-04 | 653 | 44 | 6 | 22586326 | ||
| Pubmed | 1.80e-04 | 222 | 44 | 4 | 37071664 | ||
| Pubmed | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers. | 1.81e-04 | 954 | 44 | 7 | 36373674 | |
| Pubmed | MYC multimers shield stalled replication forks from RNA polymerase. | 2.25e-04 | 989 | 44 | 7 | 36424410 | |
| Pubmed | The contribution of de novo coding mutations to autism spectrum disorder. | 2.36e-04 | 18 | 44 | 2 | 25363768 | |
| Pubmed | Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells. | 2.36e-04 | 18 | 44 | 2 | 20064376 | |
| Pubmed | Defining the human deubiquitinating enzyme interaction landscape. | 2.48e-04 | 1005 | 44 | 7 | 19615732 | |
| Pubmed | p130Cas mediates the transforming properties of the anaplastic lymphoma kinase. | 2.64e-04 | 19 | 44 | 2 | 16105984 | |
| Pubmed | 2.87e-04 | 251 | 44 | 4 | 29778605 | ||
| Pubmed | Cloning and comparative mapping of the DiGeorge syndrome critical region in the mouse. | 2.93e-04 | 20 | 44 | 2 | 9740669 | |
| Pubmed | SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response. | 3.23e-04 | 259 | 44 | 4 | 30404004 | |
| Pubmed | 3.42e-04 | 107 | 44 | 3 | 11347906 | ||
| Pubmed | The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis. | 3.69e-04 | 759 | 44 | 6 | 35915203 | |
| Pubmed | 3.81e-04 | 1431 | 44 | 8 | 37142655 | ||
| Pubmed | Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. | 4.39e-04 | 281 | 44 | 4 | 28706196 | |
| Pubmed | 4.39e-04 | 281 | 44 | 4 | 24163370 | ||
| Pubmed | Physiological and pathophysiological characteristics of ataxin-3 isoforms. | 4.39e-04 | 281 | 44 | 4 | 30455355 | |
| Pubmed | 4.61e-04 | 25 | 44 | 2 | 22689267 | ||
| Pubmed | Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity. | 4.99e-04 | 26 | 44 | 2 | 33298525 | |
| Pubmed | The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. | 5.10e-04 | 807 | 44 | 6 | 22681889 | |
| Pubmed | TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. | 5.79e-04 | 28 | 44 | 2 | 29653964 | |
| Pubmed | 5.79e-04 | 28 | 44 | 2 | 10963672 | ||
| Pubmed | Identification of 14-3-3epsilon substrates from embryonic murine brain. | 6.32e-04 | 132 | 44 | 3 | 16944949 | |
| Pubmed | 6.46e-04 | 133 | 44 | 3 | 15144186 | ||
| Pubmed | 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK. | 6.65e-04 | 30 | 44 | 2 | 16306228 | |
| Pubmed | 6.65e-04 | 30 | 44 | 2 | 9405660 | ||
| Pubmed | Isolation and characterization of proteins associated with histone H3 tails in vivo. | 6.65e-04 | 30 | 44 | 2 | 17403666 | |
| Pubmed | BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. | 7.11e-04 | 31 | 44 | 2 | 23086144 | |
| Pubmed | STK11 is required for the normal program of ciliated cell differentiation in airways. | 7.11e-04 | 31 | 44 | 2 | 31636950 | |
| Pubmed | 8.06e-04 | 33 | 44 | 2 | 10704284 | ||
| Pubmed | 8.95e-04 | 340 | 44 | 4 | 24332808 | ||
| Pubmed | Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism. | 9.05e-04 | 341 | 44 | 4 | 32971831 | |
| Pubmed | SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. | 9.15e-04 | 150 | 44 | 3 | 30154076 | |
| Pubmed | LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow. | 9.35e-04 | 344 | 44 | 4 | 30333137 | |
| Pubmed | CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality. | 9.72e-04 | 605 | 44 | 5 | 28977666 | |
| Pubmed | 1.01e-03 | 37 | 44 | 2 | 10337614 | ||
| Pubmed | Large-scale mapping of human protein-protein interactions by mass spectrometry. | 1.07e-03 | 1284 | 44 | 7 | 17353931 | |
| Pubmed | 1.07e-03 | 1285 | 44 | 7 | 35914814 | ||
| Pubmed | N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective. | 1.09e-03 | 934 | 44 | 6 | 33916271 | |
| Pubmed | H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. | 1.11e-03 | 1294 | 44 | 7 | 30804502 | |
| Pubmed | A bead-based approach for large-scale identification of in vitro kinase substrates. | 1.16e-03 | 163 | 44 | 3 | 22113938 | |
| Pubmed | 1.20e-03 | 634 | 44 | 5 | 34591612 | ||
| Pubmed | 1.23e-03 | 638 | 44 | 5 | 33239621 | ||
| Pubmed | BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression. | 1.24e-03 | 1318 | 44 | 7 | 30463901 | |
| Pubmed | 1.24e-03 | 41 | 44 | 2 | 25452572 | ||
| Interaction | DDX23 interactions | 5.66e-06 | 480 | 42 | 8 | int:DDX23 | |
| Interaction | PYHIN1 interactions | 8.32e-06 | 358 | 42 | 7 | int:PYHIN1 | |
| Cytoband | 17q11.2 | 1.65e-04 | 110 | 44 | 3 | 17q11.2 | |
| Cytoband | 17p13 | 4.94e-04 | 34 | 44 | 2 | 17p13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr17q11 | 6.01e-04 | 171 | 44 | 3 | chr17q11 | |
| GeneFamily | EF-hand domain containing | 1.72e-03 | 219 | 20 | 3 | 863 | |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | 2.15e-02 | 206 | 20 | 2 | 682 | |
| Drug | B202 | 3.48e-06 | 2 | 43 | 2 | CID006435965 | |
| Drug | B 207 | 2.09e-05 | 4 | 43 | 2 | CID000063369 | |
| Drug | Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A | 2.93e-05 | 191 | 43 | 5 | 6644_DN | |
| Drug | ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A | 3.24e-05 | 195 | 43 | 5 | 6918_UP | |
| Drug | Demecarium bromide [56-94-0]; Down 200; 5.6uM; HL60; HG-U133A | 3.32e-05 | 196 | 43 | 5 | 1781_DN | |
| Drug | Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A | 3.48e-05 | 198 | 43 | 5 | 2730_DN | |
| Drug | Riluzole hydrochloride; Down 200; 14.8uM; PC3; HT_HG-U133A | 3.56e-05 | 199 | 43 | 5 | 7365_DN | |
| Drug | Glipizide [29094-61-9]; Up 200; 9uM; HL60; HG-U133A | 3.65e-05 | 200 | 43 | 5 | 2008_UP | |
| Drug | Rolipram [61413-54-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A | 3.65e-05 | 200 | 43 | 5 | 6449_DN | |
| Disease | proline measurement, amino acid measurement | 1.88e-05 | 5 | 41 | 2 | EFO_0005134, EFO_0009773 | |
| Disease | Bardet-Biedl syndrome (implicated_via_orthology) | 1.03e-04 | 11 | 41 | 2 | DOID:1935 (implicated_via_orthology) | |
| Disease | proline measurement | 5.99e-04 | 26 | 41 | 2 | EFO_0009773 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| MHQVRDREMPEVVEI | 206 | Q5VTM2 | |
| IVEEQRKIHEERMKL | 226 | Q9NWB6 | |
| HIMMERERKRQEEEE | 21 | Q13227 | |
| VEHRIREEQRAMDQK | 126 | Q14129 | |
| QKRIEERHREMENAI | 51 | Q5BKX8 | |
| VHVVTLEDMREIEKN | 616 | Q9NTZ6 | |
| VHRVHELEEMVKDQE | 376 | Q86YS3 | |
| KDEIQGVIDEIRMHL | 716 | P20585 | |
| LRTEEKVVAEMEEHQ | 546 | Q9Y692 | |
| MELEELRHEKEMQRE | 466 | Q8TBA6 | |
| IAEVQEMEKHRIESE | 861 | Q6DN90 | |
| AREVETLRQEHRKEM | 851 | Q9ULE4 | |
| MHRDVKVENILLDER | 226 | Q96LW2 | |
| RELEEKMHEQEKIRE | 316 | H0YM25 | |
| EFMVEEHELRKERIQ | 406 | Q9BSJ2 | |
| EEERLRMREHVMNEV | 291 | P80303 | |
| RDILHETKTQMEVRE | 476 | Q9Y2F5 | |
| ERAVVHMDERREEQI | 81 | Q9H2U1 | |
| KVEARINEEIERVMH | 236 | Q13618 | |
| EEEIQREMVKLRREI | 246 | Q8NCU4 | |
| VEHRIREEQRAMDQK | 126 | Q9BY27 | |
| HRELRSEEENQEKMI | 336 | Q8TDC3 | |
| RDMTEVVHIKDRKEV | 396 | Q6ZMW3 | |
| DESIRRHMEQIEQRK | 751 | Q9BY12 | |
| EKGREEQERRHQMEL | 841 | Q9UPN4 | |
| VEGELEEMERKHQQL | 871 | P35580 | |
| LKEIFMQVEDERRHA | 1851 | P35580 | |
| HEKQQERVREQMEVV | 516 | Q16363 | |
| MLEKEQVAHIRAERD | 126 | Q9Y2H1 | |
| IKDEQDMVHIRREIE | 91 | O60285 | |
| RVMEIVDADEKVRHS | 201 | Q9Y5B9 | |
| RIMHDEVSETENIRK | 421 | Q13972 | |
| ALEHMQKQTIEERER | 171 | Q9BXT8 | |
| DAQMLIEDVKRIVHE | 856 | Q7KZ85 | |
| MREQHLTKEEREIRQ | 156 | O75533 | |
| HKILEDMERRGVEFV | 236 | Q3KQV9 | |
| NRHTIEMIEKEQREV | 1031 | Q92576 | |
| EELEDEEERNHRQMI | 581 | Q9BVJ6 | |
| ALEEVKEAMQRIHDR | 356 | Q9HCJ6 | |
| MLEELVSRIDEQVHR | 391 | Q8WUA7 | |
| IEKAEIHEKVVERRE | 226 | Q96NB3 | |
| KELVLMEHEGRDVVI | 786 | Q5TAH2 | |
| VIRHKEVMPREEEQA | 1336 | Q6ZQQ6 | |
| VIREEMERMLHVVDG | 111 | Q8NFA0 | |
| MSKEQVEEHVSRIRE | 26 | O95995 | |
| DREMEEAEERHQVEI | 81 | O95995 |