Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

VLDLR THBS1 EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 PADI2 FBN3 RYR2 CRB2

9.99e-087497515GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

THBS1 FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 FBN3

5.24e-07188758GO:0005201
GeneOntologyMolecularFunctiongrowth factor binding

THBS1 IGF1R LRP2 LTBP2 LTBP3 EPHA7

2.67e-05156756GO:0019838
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1 LRP2

2.75e-0516753GO:0005041
GeneOntologyMolecularFunctionproteoglycan binding

THBS1 FN1 LRP1 CTSL

4.01e-0551754GO:0043394
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1 LRP2

6.45e-0521753GO:0030228
GeneOntologyMolecularFunctionprotein-arginine omega-N symmetric methyltransferase activity

PRMT9 PRMT7

8.31e-054752GO:0035243
GeneOntologyMolecularFunctionsulfur compound binding

THBS1 FN1 EFEMP2 TENM1 LRP1 LTBP2 RYR2

2.10e-04323757GO:1901681
GeneOntologyMolecularFunctionpeptidase regulator activity

WFDC13 THBS1 FN1 CTSL RECK CRB2

4.11e-04257756GO:0061134
GeneOntologyMolecularFunctionheparin binding

THBS1 FN1 EFEMP2 TENM1 LTBP2

7.81e-04192755GO:0008201
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN2 EFEMP2

8.97e-0412752GO:0030023
GeneOntologyMolecularFunctionarginine N-methyltransferase activity

PRMT9 PRMT7

8.97e-0412752GO:0016273
GeneOntologyMolecularFunctionprotein-arginine N-methyltransferase activity

PRMT9 PRMT7

8.97e-0412752GO:0016274
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

IGF1R LRP2

1.06e-0313752GO:0031994
GeneOntologyMolecularFunctionaxon guidance receptor activity

HMCN2 EPHA7

1.06e-0313752GO:0008046
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN2 EFEMP2

1.23e-0314752GO:0097493
GeneOntologyMolecularFunctionhistone H4 methyltransferase activity

NSD1 PRMT7

1.83e-0317752GO:0140939
GeneOntologyMolecularFunctioninsulin-like growth factor binding

IGF1R LRP2

2.28e-0319752GO:0005520
GeneOntologyMolecularFunctionhistone methyltransferase activity

NSD1 PRMT9 PRMT7

2.42e-0371753GO:0042054
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP1

2.53e-0320752GO:0034185
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

VLDLR THBS1 PRICKLE1 ZMYND8 TENM1 LRP1 PPP1R16B TRIOBP CDK5RAP2 PRKCH XAF1 SSH2 BECN1 GBA2 PDLIM5 EPHA7

2.59e-0611897216GO:0044087
GeneOntologyBiologicalProcesstube development

THBS1 EGF FN1 PRICKLE1 EFEMP2 LRP1 PPP1R16B MUC19 LRP2 LTBP3 C6 BECN1 CTSL RECK RYR2 EPHA7

2.07e-0514027216GO:0035295
GeneOntologyBiologicalProcesstube morphogenesis

THBS1 EGF FN1 PRICKLE1 EFEMP2 LRP1 PPP1R16B LRP2 C6 BECN1 CTSL RECK RYR2 EPHA7

2.91e-0511257214GO:0035239
GeneOntologyBiologicalProcessneuron development

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 ZMYND8 TENM1 LRP1 LRP2 TRIOBP BECN1 GBA2 PDLIM5 CRB2 EPHA7

3.49e-0514637216GO:0048666
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

THBS1 FBN2 LRP1 LRP2 BAMBI LTBP2 LTBP3 BECN1 CRB2

4.45e-05482729GO:0007178
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 TRIOBP PDLIM5 EPHA7

5.33e-057487211GO:0048667
GeneOntologyBiologicalProcesstranscytosis

IGF1R LRP1 LRP2

7.83e-0524723GO:0045056
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

THBS1 EGF FN1 EIF2B2 LRP1 PPP1R16B BAMBI FGD5 C6 RECK PDLIM5 CRB2 EPHA7

9.02e-0510907213GO:0022603
GeneOntologyBiologicalProcessregulation of cell junction assembly

VLDLR THBS1 PRICKLE1 LRP1 PRKCH PDLIM5 EPHA7

1.01e-04309727GO:1901888
GeneOntologyBiologicalProcesscirculatory system development

THBS1 IGF1R EGF FN1 PRICKLE1 EFEMP2 LRP1 PPP1R16B LRP2 C6 BECN1 RECK PDLIM5 RYR2 CRB2

1.13e-0414427215GO:0072359
GeneOntologyBiologicalProcessregulation of cellular component size

FN1 EIF2B2 TENM1 LRP1 TRIOBP SSH2 GBA2 EPHA7

1.17e-04426728GO:0032535
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.19e-045722GO:1905167
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.19e-045722GO:0061642
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

THBS1 FBN2 LRP1 LRP2 BAMBI LTBP2 LTBP3 CRB2

1.58e-04445728GO:0141091
GeneOntologyBiologicalProcessfilopodium assembly

ZMYND8 TENM1 PPP1R16B FGD5

1.60e-0478724GO:0046847
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

THBS1 IGF1R FBN2 LRP1 BAMBI LTBP2 LTBP3

1.70e-04336727GO:0071560
GeneOntologyBiologicalProcessaorta development

PRICKLE1 EFEMP2 LRP1 LRP2

1.77e-0480724GO:0035904
GeneOntologyBiologicalProcessembryonic morphogenesis

FBN2 FN1 PRICKLE1 ARMC5 NSD1 LRP2 TRIOBP RECK RYR2 CRB2

1.77e-047137210GO:0048598
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

THBS1 IGF1R FBN2 LRP1 BAMBI LTBP2 LTBP3

1.93e-04343727GO:0071559
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

THBS1 IGF1R FBN2 EGF PRICKLE1 LRP1 LRP2 BAMBI LTBP2 LTBP3 BECN1 CRB2 EPHA7

2.09e-0411867213GO:0007167
GeneOntologyBiologicalProcesscell morphogenesis

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 TRIOBP BAMBI FGD5 PDLIM5 EPHA7

2.23e-0411947213GO:0000902
GeneOntologyBiologicalProcessgastrulation with mouth forming second

PRICKLE1 NSD1 CRB2

2.46e-0435723GO:0001702
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

2.50e-047722GO:1904352
GeneOntologyBiologicalProcesstissue morphogenesis

IGF1R EGF PRICKLE1 ARMC5 EFEMP2 LRP2 CTSL RYR2 CRB2 EPHA7

2.66e-047507210GO:0048729
GeneOntologyBiologicalProcessantigen processing and presentation of peptide or polysaccharide antigen via MHC class II

THBS1 HLA-DQA2 CTSL

3.15e-0438723GO:0002504
GeneOntologyBiologicalProcesspeptidyl-arginine methylation, to asymmetrical-dimethyl arginine

PRMT9 PRMT7

3.32e-048722GO:0019919
GeneOntologyBiologicalProcessblood vessel development

THBS1 EGF FN1 PRICKLE1 EFEMP2 LRP1 PPP1R16B LRP2 C6 BECN1 RECK

3.56e-049297211GO:0001568
GeneOntologyBiologicalProcessamyloid-beta clearance

IGF1R LRP1 LRP2

3.67e-0440723GO:0097242
GeneOntologyBiologicalProcessphosphatidylinositol 3-kinase/protein kinase B signal transduction

THBS1 IGF1R EGF FN1 PPP1R16B LRP2 BECN1

3.70e-04382727GO:0043491
GeneOntologyBiologicalProcessestablishment of cell polarity

IGF1R MCPH1 PRICKLE1 CDK5RAP2 CRB2

3.87e-04177725GO:0030010
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

THBS1 LRP1 EPHA7

3.95e-0441723GO:1901889
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

THBS1 FBN2 LRP1 BAMBI LTBP2 LTBP3

4.05e-04276726GO:0007179
GeneOntologyBiologicalProcesspeptidyl-arginine omega-N-methylation

PRMT9 PRMT7

4.26e-049722GO:0035247
GeneOntologyBiologicalProcessneuron projection morphogenesis

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 PDLIM5 EPHA7

4.52e-048027210GO:0048812
GeneOntologyBiologicalProcessvasculature development

THBS1 EGF FN1 PRICKLE1 EFEMP2 LRP1 PPP1R16B LRP2 C6 BECN1 RECK

5.07e-049697211GO:0001944
GeneOntologyBiologicalProcessblood vessel morphogenesis

THBS1 EGF FN1 EFEMP2 LRP1 PPP1R16B LRP2 C6 BECN1 RECK

5.22e-048177210GO:0048514
GeneOntologyBiologicalProcesscell junction organization

VLDLR THBS1 IGF1R HMCN2 FN1 PRICKLE1 ZMYND8 LRP1 PRKCH PDLIM5 EPHA7

5.30e-049747211GO:0034330
GeneOntologyBiologicalProcesspeptidyl-arginine N-methylation

PRMT9 PRMT7

5.31e-0410722GO:0035246
GeneOntologyBiologicalProcessnegative regulation of metallopeptidase activity

LRP1 RECK

5.31e-0410722GO:1905049
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 PDLIM5 EPHA7

5.32e-048197210GO:0120039
GeneOntologyBiologicalProcessregulation of peptidase activity

WFDC13 THBS1 LRP1 CTSL RECK CRB2 EPHA7

5.33e-04406727GO:0052547
GeneOntologyBiologicalProcesscell projection morphogenesis

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 PDLIM5 EPHA7

5.69e-048267210GO:0048858
GeneOntologyBiologicalProcessapoptotic cell clearance

THBS1 LRP1 BECN1

6.30e-0448723GO:0043277
GeneOntologyBiologicalProcessdevelopmental cell growth

FN1 PRICKLE1 EIF2B2 LRP1 PDLIM5 EPHA7

6.40e-04301726GO:0048588
GeneOntologyBiologicalProcesspeptidyl-arginine methylation

PRMT9 PRMT7

6.48e-0411722GO:0018216
GeneOntologyBiologicalProcessresponse to vitamin E

IGF1R BECN1

6.48e-0411722GO:0033197
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

VLDLR IGF1R FN1 EIF2B2 ZMYND8 TENM1 LRP1 PPP1R16B PDLIM5 EPHA7

6.84e-048467210GO:0120035
GeneOntologyBiologicalProcesscell-substrate junction organization

THBS1 FN1 PRICKLE1 LRP1

7.04e-04115724GO:0150115
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

THBS1 IGF1R FBN2 LRP1 LRP2 BAMBI LTBP2 LTBP3 BECN1 CRB2

7.09e-048507210GO:0071363
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

7.75e-0412722GO:1905165
GeneOntologyBiologicalProcessaxonogenesis

IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 LRP1 LRP2 EPHA7

7.83e-04566728GO:0007409
GeneOntologyBiologicalProcessregulation of cell projection organization

VLDLR IGF1R FN1 EIF2B2 ZMYND8 TENM1 LRP1 PPP1R16B PDLIM5 EPHA7

7.97e-048637210GO:0031344
GeneOntologyBiologicalProcesscell junction assembly

VLDLR THBS1 FN1 PRICKLE1 LRP1 PRKCH PDLIM5 EPHA7

8.10e-04569728GO:0034329
GeneOntologyBiologicalProcesscentral nervous system development

VLDLR IGF1R EGF MCPH1 EIF2B2 LRP1 LRP2 CDK5RAP2 GBA2 PADI2 RECK EPHA7

8.35e-0411977212GO:0007417
GeneOntologyBiologicalProcessnegative regulation of peptidase activity

WFDC13 THBS1 LRP1 RECK CRB2

8.39e-04210725GO:0010466
GeneOntologyBiologicalProcessgastrulation

FN1 PRICKLE1 ARMC5 NSD1 CRB2

8.76e-04212725GO:0007369
GeneOntologyBiologicalProcessregulation of extent of cell growth

FN1 EIF2B2 LRP1 EPHA7

8.79e-04122724GO:0061387
GeneOntologyBiologicalProcesspositive regulation of axon extension

FN1 EIF2B2 LRP1

9.39e-0455723GO:0045773
GeneOntologyBiologicalProcessresponse to growth factor

THBS1 IGF1R FBN2 LRP1 LRP2 BAMBI LTBP2 LTBP3 BECN1 CRB2

9.49e-048837210GO:0070848
GeneOntologyBiologicalProcesspositive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

THBS1 IGF1R EGF FN1 BECN1

9.72e-04217725GO:0051897
GeneOntologyBiologicalProcessregulation of filopodium assembly

ZMYND8 TENM1 PPP1R16B

1.04e-0357723GO:0051489
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

1.06e-0314722GO:1904350
GeneOntologyBiologicalProcesspeptidyl-arginine modification

PRMT9 PRMT7

1.06e-0314722GO:0018195
GeneOntologyBiologicalProcessregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

THBS1 IGF1R EGF FN1 PPP1R16B BECN1

1.10e-03334726GO:0051896
GeneOntologyBiologicalProcessregulation of proteolysis

WFDC13 THBS1 EGF PRICKLE1 LRP1 CTSL RECK CRB2 EPHA7

1.14e-03748729GO:0030162
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

VLDLR EGF FCER2 LRP1 LRP2 CTSL

1.15e-03337726GO:0006898
GeneOntologyBiologicalProcessartery development

PRICKLE1 EFEMP2 LRP1 LRP2

1.21e-03133724GO:0060840
GeneOntologyBiologicalProcessengulfment of apoptotic cell

THBS1 BECN1

1.23e-0315722GO:0043652
GeneOntologyBiologicalProcessregulation of protein polymerization

TENM1 TRIOBP CDK5RAP2 SSH2 GBA2

1.28e-03231725GO:0032271
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

THBS1 FBN2 LRP1 LRP2 BAMBI CRB2

1.33e-03347726GO:0090092
GeneOntologyBiologicalProcessregulation of anatomical structure size

FN1 EIF2B2 TENM1 LRP1 TRIOBP SSH2 GBA2 EPHA7

1.38e-03618728GO:0090066
GeneOntologyBiologicalProcessanimal organ morphogenesis

THBS1 IGF1R FBN2 PRICKLE1 EFEMP2 MUC19 LRP2 TRIOBP LTBP3 CTSL RYR2 CRB2

1.38e-0312697212GO:0009887
GeneOntologyBiologicalProcessantigen processing and presentation

THBS1 FCER2 HLA-DQA2 CTSL

1.43e-03139724GO:0019882
GeneOntologyBiologicalProcessregulation of protein localization to membrane

LYPLAL1 ZMYND8 LRP1 PRKCH SLC5A3

1.44e-03237725GO:1905475
GeneOntologyBiologicalProcessneuron projection development

VLDLR IGF1R HMCN2 FN1 PRICKLE1 EIF2B2 ZMYND8 LRP1 LRP2 TRIOBP PDLIM5 EPHA7

1.54e-0312857212GO:0031175
GeneOntologyBiologicalProcessnegative regulation of cell-substrate junction organization

THBS1 LRP1

1.58e-0317722GO:0150118
GeneOntologyBiologicalProcessnegative regulation of focal adhesion assembly

THBS1 LRP1

1.58e-0317722GO:0051895
GeneOntologyBiologicalProcesspositive regulation of axon regeneration

IGF1R LRP1

1.58e-0317722GO:0048680
GeneOntologyCellularComponentcollagen-containing extracellular matrix

THBS1 EYS FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 ALB LTBP3 CTSL

2.48e-065307411GO:0062023
GeneOntologyCellularComponentextracellular matrix

THBS1 EYS FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 ALB LTBP3 CTSL FBN3

3.06e-066567412GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

THBS1 EYS FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 ALB LTBP3 CTSL FBN3

3.15e-066587412GO:0030312
GeneOntologyCellularComponentmicrofibril

FBN2 EFEMP2 FBN3

1.19e-0513743GO:0001527
GeneOntologyCellularComponentplatelet alpha granule lumen

THBS1 EGF FN1 ALB

9.37e-0567744GO:0031093
GeneOntologyCellularComponentplatelet alpha granule

THBS1 EGF FN1 ALB

3.33e-0493744GO:0031091
GeneOntologyCellularComponentfibrinogen complex

THBS1 FN1

3.41e-048742GO:0005577
GeneOntologyCellularComponentendocytic vesicle

EGF HLA-DQA2 LRP1 LRP2 BECN1 CTSL ATP6V0A2

4.18e-04384747GO:0030139
GeneOntologyCellularComponentbasement membrane

HMCN2 FN1 EFEMP2 ALB

9.27e-04122744GO:0005604
GeneOntologyCellularComponentendocytic vesicle membrane

EGF HLA-DQA2 LRP1 LRP2 ATP6V0A2

9.34e-04212745GO:0030666
GeneOntologyCellularComponentside of membrane

THBS1 FCER2 HLA-DQA2 LRP1 LRP2 SLAMF7 BECN1 CTSL RECK RYR2

9.94e-048757410GO:0098552
GeneOntologyCellularComponentlysosomal membrane

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 ATP6V0A2

1.24e-03462747GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 ATP6V0A2

1.24e-03462747GO:0098852
GeneOntologyCellularComponentvacuole

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 BECN1 PADI2 CTSL ATP6V0A2

1.37e-039137410GO:0005773
GeneOntologyCellularComponentvacuolar membrane

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 ATP6V0A2

2.10e-03507747GO:0005774
GeneOntologyCellularComponentlysosome

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 PADI2 CTSL ATP6V0A2

2.20e-03811749GO:0005764
GeneOntologyCellularComponentlytic vacuole

VLDLR EGF HLA-DQA2 LRP1 LRP2 ZFYVE26 PADI2 CTSL ATP6V0A2

2.20e-03811749GO:0000323
GeneOntologyCellularComponentexternal side of plasma membrane

THBS1 FCER2 HLA-DQA2 LRP1 LRP2 SLAMF7 CTSL

2.39e-03519747GO:0009897
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

EGF HLA-DQA2 LRP2

2.78e-0379743GO:0030669
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LRP1 LRP2

2.88e-0380743GO:0005905
DomainEGF-like_CS

VLDLR THBS1 EYS FBN2 HMCN2 EGF FN1 TMEM8B EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 C6 FBN3 CRB2 EPHA7

8.29e-182617418IPR013032
DomainEGF_1

VLDLR THBS1 EYS FBN2 HMCN2 EGF FN1 TMEM8B EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 C6 FBN3 CRB2

1.34e-162557417PS00022
DomainEGF_2

VLDLR THBS1 EYS FBN2 HMCN2 EGF TMEM8B EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 C6 FBN3 CRB2 EPHA7

2.55e-162657417PS01186
DomainEGF_3

VLDLR THBS1 EYS FBN2 HMCN2 EGF TMEM8B EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 C6 FBN3 CRB2

8.32e-162357416PS50026
DomainEGF_CA

VLDLR THBS1 EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

1.53e-151227413SM00179
DomainEGF-like_Ca-bd_dom

VLDLR THBS1 EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

1.90e-151247413IPR001881
DomainEGF_Ca-bd_CS

VLDLR EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

3.21e-15977412IPR018097
DomainEGF_CA

VLDLR EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

4.14e-15997412PS01187
DomainASX_HYDROXYL

VLDLR EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

4.69e-151007412PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR EYS FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

9.65e-151067412IPR000152
DomainEGF_CA

VLDLR THBS1 FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3

3.36e-14867411PF07645
DomainGrowth_fac_rcpt_

VLDLR EYS IGF1R FBN2 HMCN2 EGF EFEMP2 LRP1 LRP2 LTBP2 LTBP3 FBN3 EPHA7

3.92e-141567413IPR009030
DomainEGF-like_dom

VLDLR THBS1 EYS FBN2 HMCN2 EGF EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 C6 FBN3 CRB2

4.44e-142497415IPR000742
DomainEGF

VLDLR THBS1 EYS FBN2 EGF TMEM8B EFEMP2 TENM1 LRP1 LRP2 LTBP2 LTBP3 FBN3 CRB2

3.95e-132357414SM00181
DomaincEGF

FBN2 EFEMP2 LRP1 LRP2 LTBP3 FBN3

6.80e-1026746IPR026823
DomaincEGF

FBN2 EFEMP2 LRP1 LRP2 LTBP3 FBN3

6.80e-1026746PF12662
DomainTB

FBN2 LTBP2 LTBP3 FBN3

7.87e-097744PF00683
Domain-

VLDLR TRIM2 EGF TENM1 LRP1 LRP2

9.25e-09397462.120.10.30
Domain-

FBN2 LTBP2 LTBP3 FBN3

1.57e-0887443.90.290.10
Domain6-blade_b-propeller_TolB-like

VLDLR TRIM2 EGF TENM1 LRP1 LRP2

2.60e-0846746IPR011042
DomainTB

FBN2 LTBP2 LTBP3 FBN3

2.82e-089744PS51364
DomainTB_dom

FBN2 LTBP2 LTBP3 FBN3

2.82e-089744IPR017878
DomainEGF

VLDLR EYS EGF LRP1 LRP2 LTBP2 FBN3 CRB2

3.56e-08126748PF00008
DomainhEGF

EYS FBN2 LTBP3 FBN3 CRB2

7.79e-0828745PF12661
DomainLdl_recept_b

VLDLR EGF LRP1 LRP2

2.21e-0714744PF00058
DomainLDLRB

VLDLR EGF LRP1 LRP2

2.21e-0714744PS51120
DomainLY

VLDLR EGF LRP1 LRP2

3.00e-0715744SM00135
DomainLDLR_classB_rpt

VLDLR EGF LRP1 LRP2

3.00e-0715744IPR000033
DomainLDLR_class-A_CS

VLDLR LRP1 LRP2 C6

1.86e-0540744IPR023415
DomainLdl_recept_a

VLDLR LRP1 LRP2 C6

2.99e-0545744PF00057
DomainLDLRA_1

VLDLR LRP1 LRP2 C6

3.87e-0548744PS01209
DomainLDLRA_2

VLDLR LRP1 LRP2 C6

4.20e-0549744PS50068
DomainLDrepeatLR_classA_rpt

VLDLR LRP1 LRP2 C6

4.20e-0549744IPR002172
DomainLDLa

VLDLR LRP1 LRP2 C6

4.20e-0549744SM00192
DomainFBN

FBN2 FBN3

4.63e-053742IPR011398
DomainSAM_MT_PRMT

PRMT9 PRMT7

5.48e-049742PS51678
DomainArg_MeTrfase

PRMT9 PRMT7

5.48e-049742IPR025799
Domain-

VLDLR LRP1 LRP2

8.02e-04467434.10.400.10
DomainZnf_TRAF

XAF1 FBXO30

9.96e-0412742IPR001293
DomainZF_TRAF

XAF1 FBXO30

1.17e-0313742PS50145
DomainNHL

TRIM2 TENM1

1.17e-0313742PS51125
DomainTIL_dom

MUC19 LRP2

1.37e-0314742IPR002919
DomainLaminin_G

THBS1 EYS CRB2

1.58e-0358743IPR001791
DomainEGF_extracell

TENM1 LRP2 LTBP2

1.74e-0360743IPR013111
DomainEGF_2

TENM1 LRP2 LTBP2

1.74e-0360743PF07974
DomainZnf_FYVE_PHD

ZMYND8 NSD1 ZFYVE26 FGD5

2.77e-03147744IPR011011
DomainPWWP

ZMYND8 NSD1

2.81e-0320742SM00293
DomainPWWP

ZMYND8 NSD1

3.71e-0323742PF00855
DomainPWWP_dom

ZMYND8 NSD1

3.71e-0323742IPR000313
DomainPWWP

ZMYND8 NSD1

4.04e-0324742PS50812
DomainFYVE

ZFYVE26 FGD5

5.87e-0329742PF01363
DomainFYVE

ZFYVE26 FGD5

5.87e-0329742SM00064
Domain-

THBS1 EYS CRB2

6.37e-03957432.60.120.200
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 FN1 EFEMP2 LTBP2 LTBP3 FBN3

7.83e-0937586M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 FN1 EFEMP2 LTBP2 LTBP3 FBN3

2.33e-0844586M26969
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 FN1 EFEMP2 LTBP2 LTBP3

1.83e-0732585MM14854
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 FN1 EFEMP2 LTBP2 LTBP3

5.11e-0739585MM14601
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 FBN2 FN1 EFEMP2 COL6A5 LTBP2 LTBP3 CTSL FBN3

3.39e-06300589M610
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 FBN2 FN1 EFEMP2 COL6A5 LTBP2 LTBP3 CTSL

9.81e-06258588MM14572
PathwayWP_COMPLEMENT_SYSTEM

THBS1 FCER2 LRP2 ALB C6

4.54e-0596585M39581
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

THBS1 EGF BAMBI LTBP3

9.92e-0559584M39886
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN2 LTBP2 FBN3

1.43e-0425583M39713
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN2 FN1 COL6A5 CTSL FBN3

2.70e-04140585M587
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

BAMBI LTBP2 LTBP3

5.03e-0438583MM14874
PathwayPID_UPA_UPAR_PATHWAY

VLDLR FN1 LRP1

6.77e-0442583M174
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

VLDLR THBS1 FN1 EFEMP2 ZMYND8 LRP1 PPP1R16B LRP2 TRIOBP LTBP3 PJA1 BECN1 PADI2 CTSL RECK PDLIM5

1.21e-081285751635914814
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN2 FN1 FBN3

3.85e-08475325034023
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

THBS1 LRP1 LRP2

3.85e-0847537775583
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LRP1 LRP2

9.60e-08575318685438
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

THBS1 FBN2 HMCN2 FN1 COL6A5 LTBP2 CTSL

1.08e-0717575728071719
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LRP1 LRP2

3.35e-07775312169628
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

THBS1 FBN2 LRP1 LRP2 LTBP3

4.75e-077175533541421
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

THBS1 FBN2 FN1 EFEMP2 LTBP2

1.24e-068675528327460
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

THBS1 HMCN2 FN1 EFEMP2 COL6A5 LTBP2

1.71e-0616775622159717
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1 LRP2

3.45e-061475315082773
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP1 LRP2

3.45e-061475317389516
Pubmed

Megalin/gp330 mediates uptake of albumin in renal proximal tubule.

LRP2 ALB

4.59e-0627528898021
Pubmed

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans.

THBS1 LRP1

4.59e-06275214991768
Pubmed

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

LTBP2 LTBP3

4.59e-0627527798248
Pubmed

Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I.

IGF1R LRP2

4.59e-06275216306401
Pubmed

Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein.

THBS1 LRP1

4.59e-0627529045712
Pubmed

Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1).

THBS1 LRP1

4.59e-06275217154366
Pubmed

Regulation of T-lymphocyte motility, adhesion and de-adhesion by a cell surface mechanism directed by low density lipoprotein receptor-related protein 1 and endogenous thrombospondin-1.

THBS1 LRP1

4.59e-06275224877199
Pubmed

OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation.

OTUB2 PJA1

4.59e-06275235611163
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

4.59e-06275234445520
Pubmed

Further delineation of familial polycystic ovary syndrome (PCOS) via whole-exome sequencing: PCOS-related rare FBN3 and FN1 gene variants are identified.

FN1 FBN3

4.59e-06275235141985
Pubmed

Differences in susceptibility of inbred and outbred infant mice to enterotoxigenic Escherichia coli of bovine, porcine and human origin.

FBN2 FN1

4.59e-0627522179554
Pubmed

8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.

LTBP2 LTBP3

4.59e-0627529602168
Pubmed

FN1-EGF gene fusions are recurrent in calcifying aponeurotic fibroma.

EGF FN1

4.59e-06275226691015
Pubmed

Clinical and cellular features in patients with primary autosomal recessive microcephaly and a novel CDK5RAP2 mutation.

MCPH1 CDK5RAP2

4.59e-06275223587236
Pubmed

Three-dimensional visualization of extracellular matrix networks during murine development.

FBN2 FN1

4.59e-06275229352963
Pubmed

The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.

FN1 LRP1

4.59e-06275211867643
Pubmed

Incorporation of thrombospondin into fibrin clots.

THBS1 FN1

4.59e-0627523997886
Pubmed

Antigen-induced regulation of T-cell motility, interaction with antigen-presenting cells and activation through endogenous thrombospondin-1 and its receptors.

THBS1 LRP1

4.59e-06275225393517
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

VLDLR LRP1

4.59e-06275215327526
Pubmed

LRP1 is required for novobiocin-mediated fibronectin turnover.

FN1 LRP1

4.59e-06275230061663
Pubmed

Mechanisms of albumin uptake by proximal tubular cells.

LRP2 ALB

4.59e-06275211158855
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

THBS1 FBN2 FN1 EFEMP2

4.99e-065275430389913
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LRP1 LRP2

7.68e-061875310827173
Pubmed

Integral and associated lysosomal membrane proteins.

EGF LRP1 LRP2 ZFYVE26 ATP6V0A2

8.12e-0612675517897319
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

THBS1 EYS EGF FN1 ARPC1A LRP2 CDK5RAP2 PRKCH ALB PADI2 CRB2

1.11e-051016751119056867
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP1 LRP2

1.25e-052175321337463
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

VLDLR THBS1

1.37e-05375218032585
Pubmed

IGFBP-3 can either inhibit or enhance EGF-mediated growth of breast epithelial cells dependent upon the presence of fibronectin.

EGF FN1

1.37e-05375220851879
Pubmed

Hemoglobin inhibits albumin uptake by proximal tubule cells: implications for sickle cell disease.

LRP2 ALB

1.37e-05375228356267
Pubmed

TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.

THBS1 FN1

1.37e-05375218042364
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LRP1

1.37e-05375218367731
Pubmed

In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin.

THBS1 FN1

1.37e-05375211773026
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

VLDLR LRP1

1.37e-05375211931574
Pubmed

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.

LRP2 ALB

1.37e-05375210811843
Pubmed

Genetic heterogeneity in Pakistani microcephaly families revisited.

MCPH1 CDK5RAP2

1.37e-05375228004384
Pubmed

Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis.

THBS1 BECN1

1.37e-05375228174297
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

VLDLR LRP1

1.37e-05375218277139
Pubmed

Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair.

VLDLR THBS1

1.37e-05375238147128
Pubmed

Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

LTBP2 LTBP3

1.37e-05375221700711
Pubmed

Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis.

THBS1 LRP1

1.37e-05375218653767
Pubmed

Elevated glucose induction of thrombospondin-1 up-regulates fibronectin synthesis in proximal renal tubular epithelial cells through TGF-beta1 dependent and TGF-beta1 independent pathways.

THBS1 FN1

1.37e-05375216495290
Pubmed

Novel mutations in genes causing hereditary spastic paraplegia and Charcot-Marie-Tooth neuropathy identified by an optimized protocol for homozygosity mapping based on whole-exome sequencing.

ZFYVE26 GBA2

1.37e-05375226492578
Pubmed

Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action.

LTBP2 LTBP3

1.37e-05375210743502
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

THBS1 HMCN2 FN1 LTBP2 LTBP3

1.66e-0514675527068509
Pubmed

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.

GALNT15 LRP2 ALB

1.89e-052475331740596
Pubmed

Microcephaly genes and risk of late-onset Alzheimer disease.

MCPH1 CDK5RAP2

2.75e-05475221297427
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP2 LTBP3

2.75e-05475215611103
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

2.75e-05475212413896
Pubmed

A fibronectin-independent mechanism of collagen fibrillogenesis in adult liver remodeling.

THBS1 FN1

2.75e-05475221320502
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LRP1

2.75e-05475215863833
Pubmed

Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans.

THBS1 EFEMP2

2.75e-05475230355232
Pubmed

Extracellular fibrillar structure of latent TGF beta binding protein-1: role in TGF beta-dependent endothelial-mesenchymal transformation during endocardial cushion tissue formation in mouse embryonic heart.

LTBP2 LTBP3

2.75e-0547529008713
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP2 LTBP3

2.75e-05475211104663
Pubmed

Suppressor of cytokine signaling-2 limits intestinal growth and enterotrophic actions of IGF-I in vivo.

IGF1R EGF

2.75e-05475216574995
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

VLDLR LRP1

2.75e-05475215840700
Pubmed

Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2.

LTBP2 LTBP3

2.75e-05475234481123
Pubmed

Bcl-2 expression modulates cell adhesion and migration promoting branching of ureteric bud cells.

THBS1 FN1

2.75e-05475217133361
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

2.75e-05475211421580
Pubmed

Sex-dependent association of common variants of microcephaly genes with brain structure.

MCPH1 CDK5RAP2

2.75e-05475220080800
Pubmed

Epidermal growth factor and tumor necrosis factor α cooperatively promote the motility of hepatocellular carcinoma cell lines via synergistic induction of fibronectin by NF-κB/p65.

EGF FN1

2.75e-05475228844984
Pubmed

Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

FN1 LTBP3

2.75e-05475216157329
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

OTUB2 FN1 MCPH1 MUC19 LRP2 ALB C6 FBN3 DNAH14

2.93e-0573675929676528
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

THBS1 FN1 ALB CTSL EPHA7

2.99e-0516575514718574
Pubmed

Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration.

VLDLR THBS1

4.57e-05575218946489
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2

4.57e-05575219047013
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

VLDLR LRP1

4.57e-0557528013374
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

4.57e-05575216101684
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

VLDLR LRP1

4.57e-05575230700132
Pubmed

Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor.

THBS1 FN1

4.57e-05575215799029
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBN2 EFEMP2

4.57e-05575217255108
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

VLDLR LRP1

4.57e-05575212746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

VLDLR LRP1

4.57e-05575218992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

VLDLR LRP1

4.57e-05575223959870
Pubmed

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.

OTUB2 TRIOBP ALB PDLIM5

4.62e-059175430472188
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF607 ZNF257 ZNF587 ZNF417 ZNF563

4.64e-0518175537372979
Pubmed

RUNX1 and TGF-β signaling cross talk regulates Ca2+ ion channels expression and activity during megakaryocyte development.

THBS1 BAMBI LTBP2

6.00e-053575332281291
Pubmed

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.

IGF1R EGF FN1 PRICKLE1

6.18e-059875419834535
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

6.84e-0567529837937
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

VLDLR LRP1

6.84e-05675216478678
Pubmed

Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners.

EGF FN1

6.84e-05675230082873
Pubmed

Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor.

EGF PRKCH

6.84e-05675222732145
Pubmed

High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.

THBS1 FBN2

6.84e-05675218254948
Pubmed

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.

ALB CTSL

6.84e-05675228827407
Pubmed

Mapping of human and murine genes for latent TGF-beta binding protein-2 (LTBP2).

LTBP2 LTBP3

6.84e-0567527719025
Pubmed

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody.

ZFYVE26 BECN1

6.84e-05675220208530
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR IGF1R LRP1 LRP2

6.95e-0510175423382219
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

GALNT15 OTUB2 MCPH1 INTS2 LYPLAL1 EIF2B2 ZMYND8 CDK5RAP2 PRMT7 GBA2 CRB2

6.95e-051242751130973865
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

EYS EGF HLA-DQA2 RECK RYR2

7.27e-0519975523382691
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

THBS1 EYS TNRC18 ZMYND8 NSD1 CTSL

8.37e-0533275637433992
InteractionDYRK1A interactions

VLDLR THBS1 FN1 EFEMP2 LRP2 TRIOBP CDK5RAP2 LTBP3 PJA1 RECK PDLIM5

5.91e-065527511int:DYRK1A
InteractionCUBN interactions

LRP1 LRP2 ALB

2.18e-0515753int:CUBN
Cytoband9p13.3

TMEM8B GBA2 RECK

2.60e-04757539p13.3
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1 LRP2

7.05e-0613543634
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP2 LTBP3

5.23e-054542628
GeneFamilyFibulins

HMCN2 EFEMP2

2.42e-048542556
GeneFamilyProtein arginine methyltransferases

PRMT9 PRMT7

3.11e-049542691
GeneFamilyPWWP domain containing

ZMYND8 NSD1

1.95e-03225421147
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE26 FGD5

3.85e-033154281
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 EYS FBN2 HMCN2 FN1 EFEMP2 LTBP2 LTBP3 FBN3

4.99e-09196759M3008
CoexpressionNABA_CORE_MATRISOME

THBS1 EYS FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 LTBP3 FBN3

6.24e-092757510M5884
CoexpressionTAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP

THBS1 FN1 FCER2 PPP1R16B XAF1 SLAMF7 SLC5A3

7.38e-07176757M15588
CoexpressionNABA_CORE_MATRISOME

THBS1 FBN2 HMCN2 FN1 EFEMP2 COL6A5 LTBP2 LTBP3

1.06e-06270758MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

THBS1 FBN2 HMCN2 FN1 EFEMP2 LTBP2 LTBP3

1.28e-06191757MM17059
CoexpressionNABA_MATRISOME

THBS1 EYS FBN2 HMCN2 EGF FN1 EFEMP2 MUC19 COL6A5 LTBP2 LTBP3 CTSL FBN3

6.25e-0610267513M5889
CoexpressionGSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN

IGF1R LYPLAL1 CDK5RAP2 BAMBI PRMT7 PDLIM5

2.38e-05200756M4585
CoexpressionCHANDRAN_METASTASIS_UP

FN1 ZNF587 ZMYND8 NSD1 PDLIM5 CRB2

3.05e-05209756M16036
CoexpressionCHICAS_RB1_TARGETS_CONFLUENT

GALNT15 THBS1 FBN2 FN1 PRICKLE1 EFEMP2 TRIOBP XAF1 LTBP2

3.44e-05567759M2129
CoexpressionSIMBULAN_UV_RESPONSE_IMMORTALIZED_DN

THBS1 IGF1R FN1

9.55e-0531753M3732
CoexpressionBOQUEST_STEM_CELL_UP

TENM1 LRP1 LTBP2 C6 RECK SLC5A3

1.04e-04261756M1834
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

GALNT15 VLDLR THBS1 LRP1 LRP2 COL6A5 XAF1 LTBP2 LTBP3 CTSL RECK PDLIM5

1.46e-057787412gudmap_kidney_adult_RenalCapsule_1000
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HMCN2 FN1 PPP1R16B PRKCH XAF1 FGD5

3.22e-081897576463890d8dbee4bc198f91628a5f784970de786a
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 FN1 EFEMP2 BAMBI LTBP2 LTBP3 RECK

4.74e-08200757be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 FN1 EFEMP2 BAMBI LTBP2 LTBP3 RECK

4.74e-082007578e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 FN1 EFEMP2 BAMBI LTBP2 LTBP3 RECK

4.74e-08200757c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

FBN2 FN1 TENM1 COL6A5 LTBP2 RYR2

5.30e-07176756852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

FBN2 FN1 TENM1 COL6A5 LTBP2 RYR2

5.30e-07176756d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

5.85e-071797568f9e538c822940785130297712b75131812a4603
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNT15 HMCN2 FN1 PRICKLE1 LRP1 LTBP2

7.09e-071857568f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

THBS1 FN1 PRICKLE1 COL6A5 LTBP2 RYR2

7.55e-07187756e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

8.54e-07191756f663131a4810584c5854bd64ee7991a237b7707f
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THBS1 EGF PRICKLE1 PDLIM5 RYR2 ATP6V0A2

8.54e-071917567edc22e7e70697fb22690699efb352577162709b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

8.80e-0719275628eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

8.80e-07192756c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellLA|World / Chamber and Cluster_Paper

GALNT15 HMCN2 FN1 LRP1 LRP2 LTBP2

9.08e-07193756d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.08e-0719375652e918884877b6659cdca0496390e440f73694a9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.35e-0719475674a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

THBS1 HMCN2 FN1 PRICKLE1 LRP1 LTBP2

9.35e-07194756d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 FN1 EFEMP2 LRP1 COL6A5 RYR2

9.35e-071947566e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.35e-07194756b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.35e-07194756fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-071967568ad8efb631164b46f0c082572270188e5ead20bf
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

GALNT15 IGF1R PPP1R16B PRKCH FGD5 CTSL

9.93e-07196756e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-0719675622767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-07196756b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-071967569606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-07196756145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-07196756adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

9.93e-07196756d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

1.05e-06198756b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 FN1 LRP1 COL6A5 LTBP2 RYR2

1.05e-061987563ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

1.05e-06198756953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellfacs-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FN1 EFEMP2 LRP1 LTBP3 CTSL RECK

1.05e-06198756e85ae846e293687fd193f4d565525d8d3bd1faea
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH XAF1 FGD5

1.05e-061987568e45551224fbb30c0658ad47dd98335ecf165437
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

THBS1 FN1 EFEMP2 LRP1 COL6A5 RYR2

1.08e-06199756a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

THBS1 FN1 EFEMP2 LRP1 COL6A5 RECK

1.08e-0619975630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GALNT15 FN1 EFEMP2 LRP1 LTBP2 CTSL

1.12e-06200756cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

THBS1 EFEMP2 LRP1 LTBP2 LTBP3 EPHA7

1.12e-06200756a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN2 FN1 EFEMP2 BAMBI LTBP3 RECK

1.12e-06200756d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GALNT15 THBS1 FN1 LRP1 LTBP2 RYR2

1.12e-06200756cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRICKLE1 TENM1 LRP1 COL6A5 LTBP2 RYR2

1.12e-0620075658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 MUC19 LRP2 COL6A5 RYR2

7.54e-06160755c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 MUC19 LRP2 COL6A5 RYR2

7.54e-0616075525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

OTUB2 CXorf38 ARPC1A ZMYND8 SLAMF7

9.28e-06167755cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

FN1 FCER2 LRP1 CTSL CRB2

9.56e-061687558ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 ALAS2 LTBP2 C6 RYR2

9.83e-0616975512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCER2 PPP1R16B MUC19 LRP2 RYR2

1.20e-05176755c6484334187f64cd00cd35e77d8ae436556b4260
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R16B LRP2 FGD5 ALAS2 LTBP2

1.20e-051767550b3491451be02c18a16cdb875645be47eb867a7f
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 HLA-DQA2 XAF1 ZNF417

1.26e-05178755375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TNRC18 PRICKLE1 LRP2 LTBP2 RYR2

1.37e-05181755c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 TENM1 LRP2 RYR2 EPHA7

1.48e-051847552cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 TENM1 LRP2 RYR2 EPHA7

1.48e-05184755ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 TENM1 LRP2 RYR2 EPHA7

1.48e-051847552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FN1 EFEMP2 LRP1 CTSL

1.56e-05186755ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 FN1 COL6A5 LTBP2 RYR2

1.56e-051867555473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

GALNT15 HMCN2 FN1 LRP1 LTBP2

1.60e-051877554ea486991f66c29728d127171a07b81404ec0b78
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 FN1 HLA-DQA2 LRP1 FGD5

1.60e-051877557b24a324335c30c4b37795c43611b297274c804b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 FN1 HLA-DQA2 LRP1 CTSL

1.69e-05189755a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FN1 PPP1R16B PRKCH FGD5 PDLIM5

1.69e-05189755c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FN1 HLA-DQA2 LRP1 FGD5 CTSL

1.69e-05189755c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VLDLR FN1 BAMBI PDLIM5 RYR2

1.69e-05189755d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FN1 LRP1 LTBP3 EPHA7

1.77e-051917559214655dca96d766737c9f30b624d7fe7050342e
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PRICKLE1 TENM1 COL6A5 LTBP2 RYR2

1.77e-05191755e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PRICKLE1 TENM1 COL6A5 LTBP2 RYR2

1.77e-051917551726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GALNT15 THBS1 EFEMP2 LRP1 LTBP2

1.77e-051917554e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PRKCH XAF1 FGD5

1.82e-05192755bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell10x5'v1-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

THBS1 EGF PRICKLE1 PDLIM5 RYR2

1.82e-05192755b877d14be9d04ab0010e340909e3a23de92613db
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 EFEMP2 LRP1 COL6A5 RYR2

1.82e-05192755162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 FN1 LRP1 COL6A5 RYR2

1.82e-051927553d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HMCN2 PPP1R16B PRKCH FGD5

1.82e-051927553259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 EFEMP2 LRP1 COL6A5 RYR2

1.82e-05192755ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 EFEMP2 LRP1 LTBP3 CTSL

1.87e-0519375549600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PRKCH XAF1 FGD5

1.87e-051937556a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 PPP1R16B PRKCH XAF1 FGD5

1.87e-051937551f978e102a029a6beb10913052cd0a20c7253e8e
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FN1 EFEMP2 LRP1 LTBP3

1.87e-0519375545b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PRKCH XAF1 FGD5

1.87e-05193755287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PRKCH XAF1 FGD5

1.91e-05194755cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 PPP1R16B PRKCH XAF1 FGD5

1.91e-05194755f76808666fb875fc787751cbfd924d9be20a8192
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

IGF1R PRICKLE1 PDLIM5 RYR2 EPHA7

1.91e-0519475589812fb164065041357bb37a3c2d87028ec3de4e
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

GALNT15 FN1 LRP1 LTBP2 SSH2

1.91e-05194755234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 PPP1R16B PRKCH XAF1 FGD5

1.91e-05194755f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 PPP1R16B PRKCH XAF1 FGD5

1.91e-05194755e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 PPP1R16B PRKCH XAF1 FGD5

1.91e-05194755a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 FN1 PPP1R16B PRKCH FGD5

1.96e-05195755a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellP07-Mesenchymal|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS1 FN1 EFEMP2 LRP1 LTBP2

1.96e-05195755859764b605866b6c3e6edd0698670ca9c0f20745
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

GALNT15 HMCN2 FN1 LRP1 LTBP2

1.96e-05195755a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 LRP1 COL6A5 LTBP2 RYR2

1.96e-05195755df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 LRP1 COL6A5 LTBP2 RYR2

1.96e-051957554243190ad291d56694e2155954dbaa879c9d3844
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 HMCN2 PPP1R16B PRKCH FGD5

1.96e-05195755d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GALNT15 FN1 PPP1R16B PRKCH FGD5

1.96e-05195755752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCell(2)_5-FU|World / Stress and Cell class

THBS1 EFEMP2 LRP1 CTSL SLC5A3

1.96e-05195755e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 PPP1R16B PRKCH XAF1 FGD5

2.01e-05196755ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 PPP1R16B PRKCH XAF1 FGD5

2.01e-05196755023312af38f816a44b407e0daa32590d953caf99
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR IGF1R EGF CTSL SLC5A3

2.01e-05196755d74e899cc120146dded3a20716e22c7aca4f074a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH FGD5

2.01e-051967558f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH FGD5

2.01e-0519675548b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THBS1 FN1 LRP1 LTBP2 CTSL

2.01e-05196755ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GALNT15 FN1 PPP1R16B PRKCH FGD5

2.01e-05196755473980c827443464d08a0be28c53e3536369b12a
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT15 THBS1 LRP1 LTBP3 RECK

2.01e-05196755b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

GALNT15 FN1 PPP1R16B PRKCH FGD5

2.01e-05196755b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT15 THBS1 LRP1 LTBP3 RECK

2.01e-05196755787c6cd92035e0b1108c2c086c42a229016e476b
DrugVanadates

VLDLR OTUB2 EGF FN1 PRICKLE1 CXorf38 LRP1 CDK5RAP2 BAMBI PRKCH XAF1 LTBP2 ALB LTBP3 BECN1 PDLIM5

4.14e-0613027516ctd:D014638
DrugInsulin, porcine

IGF1R HLA-DQA2 LRP2

9.59e-0613753DB00071
Drugallyl isocyanate

BAMBI ALB

1.07e-052752CID000015123
Drugfuniferine N-oxide

FBN2 LTBP2 LTBP3 ATP6V0A2

2.06e-0549754CID000191631
Drugdesmosine

FBN2 FN1 EFEMP2 FBN3

2.81e-0553754CID000025435
Drug17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A

VLDLR OTUB2 TRIM2 ZMYND8 LTBP2 SLC5A3

3.36e-051857566986_UP
DrugDAPH2

IGF1R EGF PRICKLE1 PRKCH

4.03e-0558754CID006711154
DrugNizatidine [76963-41-2]; Down 200; 12uM; HL60; HT_HG-U133A

TRIM2 FN1 ZMYND8 SLAMF7 PADI2 SLC5A3

4.50e-051957563047_DN
DrugNicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A

THBS1 EGF EFEMP2 PRMT7 RECK RYR2

4.77e-051977565775_DN
DrugPNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A

THBS1 TRIM2 FBN2 TMEM8B ZMYND8 PADI2

4.77e-051977566563_UP
DrugNSC226080

THBS1 IGF1R FBN2 EGF FN1 EIF2B2 LRP1 PRKCH BECN1 FBN3 RYR2

4.83e-057827511CID000005040
DrugPrednisolone [50-24-8]; Down 200; 11uM; MCF7; HT_HG-U133A

THBS1 TRIM2 NSD1 LRP2 CDK5RAP2 PADI2

4.90e-051987565526_DN
DrugPVLA

EGF FN1 ALB

5.05e-0522753CID000126094
Drugestradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A_EA

ASB8 NSD1 TRIOBP PRKCH PADI2 PDLIM5

5.19e-052007561079_DN
DrugAmiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; HL60; HT_HG-U133A

OTUB2 FN1 ZMYND8 NSD1 LRP2 PDLIM5

5.19e-052007562434_UP
Diseasemicrocephaly (is_implicated_in)

MCPH1 NSD1 CDK5RAP2

8.06e-078733DOID:10907 (is_implicated_in)
DiseaseZollinger-Ellison syndrome (is_marker_for)

IGF1R ALB

6.04e-062732DOID:0050782 (is_marker_for)
Diseasepancreatic ductal carcinoma (is_marker_for)

THBS1 IGF1R EGF ALB

1.62e-0561734DOID:3587 (is_marker_for)
Diseaseconnective tissue disease (implicated_via_orthology)

FBN2 FBN3

1.81e-053732DOID:65 (implicated_via_orthology)
Diseaseintraocular pressure measurement

FBN2 C10orf55 MCPH1 GNB1L TRIOBP BAMBI LTBP2 LTBP3

3.73e-05509738EFO_0004695
DiseaseCutis laxa, autosomal recessive

EFEMP2 ATP6V0A2

6.01e-055732cv:C3665335
Diseaseanthropometric measurement

IGF1R FN1 LTBP2 LTBP3 PDLIM5

6.19e-05168735EFO_0004302
Diseaseosteoarthritis (is_marker_for)

IGF1R FN1 BECN1

8.98e-0535733DOID:8398 (is_marker_for)
Diseaseendometrial cancer (is_implicated_in)

EGF MCPH1 EFEMP2

9.78e-0536733DOID:1380 (is_implicated_in)
Diseasecholesteryl ester 16:2 measurement

LTBP2 LTBP3

1.26e-047732EFO_0021435
Diseaseneuroblastoma (is_implicated_in)

IGF1R NSD1

2.68e-0410732DOID:769 (is_implicated_in)
DiseaseColorectal Carcinoma

FBN2 FN1 TENM1 LRP1 LRP2 XAF1 FBXO30 EPHA7

3.40e-04702738C0009402
Diseaseoptic cup area measurement

TRIOBP LTBP2 LTBP3

3.67e-0456733EFO_0006940
DiseaseMitral valve prolapse, response to surgery

LTBP2 LTBP3

3.92e-0412732EFO_0009951, HP_0001634
Diseasedementia (is_implicated_in)

VLDLR IGF1R

3.92e-0412732DOID:1307 (is_implicated_in)
Diseasestenosing tenosynovitis

LTBP2 LTBP3

3.92e-0412732EFO_0010822
Diseasecortical thickness

THBS1 IGF1R FBN2 MCPH1 LRP1 TRIOBP CDK5RAP2 SSH2 CRB2 EPHA7

4.02e-0411137310EFO_0004840
Diseaseacute kidney failure (biomarker_via_orthology)

IGF1R EGF FN1

4.72e-0461733DOID:3021 (biomarker_via_orthology)
Diseaseglaucoma

GNB1L TRIOBP LTBP2 LTBP3

5.87e-04154734MONDO_0005041
Diseasesevere aplastic anemia

FBN2 HLA-DQA2

6.21e-0415732EFO_0006927
DiseaseAutosomal recessive primary microcephaly

MCPH1 CDK5RAP2

6.21e-0415732cv:C3711387
Diseasemyocardial infarction (biomarker_via_orthology)

THBS1 IGF1R FN1 BECN1

6.77e-04160734DOID:5844 (biomarker_via_orthology)
DiseaseDiabetic Angiopathies

THBS1 ALB

7.08e-0416732C0011875
DiseaseMicroangiopathy, Diabetic

THBS1 ALB

7.08e-0416732C0025945
DiseaseSjogren's syndrome (implicated_via_orthology)

THBS1 MUC19

8.02e-0417732DOID:12894 (implicated_via_orthology)
Diseasehypertrophic cardiomyopathy (is_marker_for)

IGF1R BECN1

8.02e-0417732DOID:11984 (is_marker_for)
DiseaseCOVID-19, mortality

LRP2 TRIOBP LTBP2 LTBP3

8.49e-04170734EFO_0004352, MONDO_0100096
DiseaseFEV/FEC ratio

LYPLAL1 GNB1L LRP1 NSD1 LTBP2 LTBP3 SSH2 PJA1 CRB2 ATP6V0A2

8.61e-0412287310EFO_0004713
DiseaseGlioblastoma

EGF FN1 RECK

1.00e-0379733C0017636
Diseasedilated cardiomyopathy (implicated_via_orthology)

LTBP2 CTSL PDLIM5

1.04e-0380733DOID:12930 (implicated_via_orthology)
DiseaseGiant Cell Glioblastoma

EGF FN1 RECK

1.20e-0384733C0334588
DiseaseNephritis, Tubulointerstitial

THBS1 ALB

1.23e-0321732C0041349
Diseaseopen-angle glaucoma

GNB1L TRIOBP LTBP2 LTBP3

1.31e-03191734EFO_0004190
DiseasePrimary microcephaly

MCPH1 CDK5RAP2

1.35e-0322732C0431350
Diseasecholangiocarcinoma (is_implicated_in)

THBS1 ALB

1.35e-0322732DOID:4947 (is_implicated_in)
DiseaseLewy Body Disease

IGF1R BECN1

1.35e-0322732C0752347
DiseaseAutosomal Recessive Primary Microcephaly

MCPH1 CDK5RAP2

1.35e-0322732C3711387
DiseaseKidney Diseases

EGF LRP2 ALB

1.37e-0388733C0022658
Diseasealcohol use disorder (implicated_via_orthology)

PRKCH SSH2 CTSL RYR2

1.41e-03195734DOID:1574 (implicated_via_orthology)
DiseaseNephritis, Interstitial

THBS1 ALB

1.61e-0324732C0027707
Diseasenephrotic syndrome (biomarker_via_orthology)

VLDLR CTSL

1.61e-0324732DOID:1184 (biomarker_via_orthology)
Diseasediabetes mellitus (implicated_via_orthology)

IGF1R LRP1

1.89e-0326732DOID:9351 (implicated_via_orthology)
Diseaseelectrocardiography

IGF1R TRIM2 C10orf55 HMCN2 PDLIM5 EPHA7

2.01e-03530736EFO_0004327
Diseasepancreatic cancer (is_marker_for)

THBS1 EGF ALB

2.03e-03101733DOID:1793 (is_marker_for)
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS CRB2

2.04e-0327732DOID:10584 (implicated_via_orthology)
DiseaseLiver Cirrhosis

THBS1 BAMBI ALB

2.15e-03103733C0023890
DiseaseHyalinosis, Segmental Glomerular

FN1 CRB2

2.19e-0328732C0086432
Diseasehyperthyroidism (biomarker_via_orthology)

IGF1R CTSL

2.19e-0328732DOID:7998 (biomarker_via_orthology)
DiseaseFibrosis, Liver

THBS1 BAMBI ALB

2.27e-03105733C0239946
Diseasesuicidal ideation

LTBP2 LTBP3

2.35e-0329732EFO_0004320

Protein segments in the cluster

PeptideGeneStartEntry
SHCIAEVENDEMPAD

ALB

311

P02768
LFPDDEVICNSMGEH

PRMT9

96

Q6P2P2
LAMEPESCGDIHCAG

ARMC5

181

Q96C12
EENPRVCDQGHCTNM

FBN3

1201

Q75N90
RCECEMGFDPTEDHR

FBN3

1386

Q75N90
MGFDPTEDHRACQDV

FBN3

1391

Q75N90
EIPNVCSHGDCMDTE

FBN3

1811

Q75N90
SENSVVAAGHDCCPM

ARPC1A

256

Q92747
CPLHCEQIGEMKAEV

CDK5RAP2

1811

Q96SN8
DENPCGIDSECINRM

NSD1

1901

Q96L73
CDQVQDPVCDTDHME

RECK

716

O95980
DPVCDTDHMEHNNLC

RECK

721

O95980
PLHCACMVSDADCVE

ASB8

56

Q9H765
KDFCTHEVEPMATEC

OTUB2

161

Q96DC9
AVMSPCGGEDIVADH

HLA-DQA2

16

P01906
CSRIACHEEPVMDLD

GNB1L

201

Q9BYB4
EHEPCFIVDCNMETS

MCPH1

581

Q8NEM0
ECIPNSCVHELCMEN

EYS

1201

Q5T1H1
SCVHELCMENEPGST

EYS

1206

Q5T1H1
VTCEMEVDECASAPC

CRB2

141

Q5IJ48
ECEEESIECGPGQMC

HMCN2

4906

Q8NDA2
QDCMDGSDEGPHCRE

LRP1

96

Q07954
MSGQTDVDHPLCEEC

BECN1

126

Q14457
GDVLVFMDAHCECHP

GALNT15

276

Q8N3T1
FVIHDGECMQECPSG

IGF1R

296

P08069
VEDVPVDGCTCPDAM

MUC19

1106

Q7Z5P9
HDACIEEACACDMEG

MUC19

1491

Q7Z5P9
AEESCQIVPFENDCM

FGD5

321

Q6ZNL6
CDDMEGQLVSIHSPE

FCER2

191

P06734
TGSMDPDVQLCHCIE

INTS2

1176

Q9H0H0
EPIEECMSSAHLCDN

LRP2

3666

P98164
DNSDERDCEMRTCHP

LRP2

3786

P98164
TICHGCEFPIEAGDM

PDLIM5

536

Q96HC4
PQVEEECCLEMHVRG

PADI2

606

Q9Y2J8
EAENAPRMHCSAEGE

EPHA7

241

Q15375
HSMDGAICPLEELCD

ALAS2

331

P22557
APIEEMEEKVHGCCR

PPP1R16B

551

Q96T49
CETCGEHIGVDHAQM

PRICKLE1

251

Q96MT3
LDLECMVPVSGHENC

BAMBI

211

Q13145
GSECICMSPEEDCSH

C6

781

P13671
ETDCCNPEDSGQLMV

GBA2

56

Q9HCG7
EIMVSDQDDCAPVGC

EGF

826

P01133
RSPCGDCEGFDVHIM

PRMT7

531

Q9NVM4
CPMAAHEEICTTNEG

FN1

461

P02751
MCTEAPEVCHLQEAD

COL6A5

991

A8TX70
FHESDQCPEECVMFE

DNAH14

556

Q0VDD8
GTVCEDVNECMGEEH

LTBP2

1171

Q14767
DVNECMGEEHCAPHG

LTBP2

1176

Q14767
THCQDINECAMPGVC

LTBP3

351

Q9NS15
DCPEHLESIDVMCQV

LYPLAL1

86

Q5VWZ2
HIPEEDQRDGCECEM

CXorf38

216

Q8TB03
VAECAPFCQGHEMAV

EIF2B2

191

P49770
TDVDECEIGAHNCDM

FBN2

1366

P35556
VAEHLEMCPASVVCC

FBXO30

76

Q8TB52
CVDVNECDMGAPCEQ

EFEMP2

201

O95967
EHEMNEIEVCPECYL

ZMYND8

246

Q9ULU4
EHGPENNPERAEMCC

RYR2

3251

Q92736
EKCPDSCAHEMESVA

PRR14L

1146

Q5THK1
DDIACINPEHCMLVC

SLC5A3

326

P53794
EDCLDPMCSNHGICV

TENM1

626

Q9UKZ4
ESEGPNMVIHVCDEA

SANBR

141

Q6NSI8
MEEVPGDALCEHFEA

TRIOBP

1

Q9H2D6
EPDCSSEDMDHGVLV

CTSL

266

P07711
VDTHMELDEVHCCPG

C10orf55

21

Q5SWW7
LEMSDCDVPAGEGQC

TNRC18

1291

O15417
MDGVGDQCDNCPLEH

THBS1

826

P07996
GHMEQDEDSCTAQPE

SSH2

801

Q76I76
AHPCEMCGLILEDVF

ZNF587

91

Q96SQ5
ECEEPVPKETMEEHC

XAF1

36

Q6GPH4
AHPCEMCGLILEDVF

ZNF417

91

Q8TAU3
ESVHADGNPYMCEEC

ZNF607

636

Q96SK3
HACDQPGIVVFCIMD

TMEM8B

276

A6NDV4
VTNLTCCMEHGEEDV

SLAMF7

146

Q9NQ25
DPCQSAECEEVIMGH

ZNF563

101

Q8TA94
CPFCGKIEEHSEDME

ZUP1

156

Q96AP4
AMCRECTEGEHAEHP

TRIM2

136

Q9C040
LVTEDHGAVGQEMCC

PJA1

581

Q8NG27
PDETESICMVCCREH

ZFYVE26

1811

Q68DK2
APENCTHLCTMQEDC

WFDC13

41

Q8IUB5
NHQVEDGCREMACEE

ATP6V0A2

711

Q9Y487
DCEDGSDESPEQCHM

VLDLR

96

P98155
VMCSHIAEDLCPERD

ZNF257

76

Q9Y2Q1
EMLCGHAPFEAENED

PRKCH

546

P24723