Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCTP synthase activity

CTPS2 CTPS1

1.88e-052872GO:0003883
GeneOntologyMolecularFunctionligase activity, forming carbon-nitrogen bonds

CTPS2 TTLL9 GART CTPS1

8.36e-0553874GO:0016879
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN4 HCN1 SCN2A

1.93e-0426873GO:0005248
GeneOntologyMolecularFunctionuridylyltransferase activity

UAP1 TUT4

3.89e-047872GO:0070569
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

HCN4 HCN1

8.26e-0410872GO:0005222
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A2 ATP12A

8.26e-0410872GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A2 ATP12A

8.26e-0410872GO:0005391
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

HCN4 HCN1 SCN2A ATP1A2 ATP12A

9.11e-04171875GO:0015081
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A2 ATP12A

1.01e-0311872GO:0008556
GeneOntologyBiologicalProcessmembrane depolarization during action potential

PTPN3 HCN4 SCN2A ATP1A2

1.50e-0536864GO:0086010
GeneOntologyBiologicalProcess'de novo' CTP biosynthetic process

CTPS2 CTPS1

1.72e-052862GO:0044210
GeneOntologyBiologicalProcesssodium ion transmembrane transport

PTPN3 HCN4 HECW2 HCN1 SCN2A ATP1A2 ATP12A

2.63e-05208867GO:0035725
GeneOntologyBiologicalProcesspositive regulation of non-canonical Wnt signaling pathway

GPC3 CSNK1D CSNK1E

5.46e-0518863GO:2000052
GeneOntologyBiologicalProcessnucleobase biosynthetic process

CTPS2 GART CTPS1

5.46e-0518863GO:0046112
GeneOntologyBiologicalProcesssodium ion transport

PTPN3 HCN4 HECW2 HCN1 SCN2A ATP1A2 ATP12A

1.52e-04275867GO:0006814
GeneOntologyBiologicalProcessmembrane depolarization

PTPN3 HCN4 HCN1 SCN2A ATP1A2

1.52e-04121865GO:0051899
GeneOntologyCellularComponentcytoophidium

CTPS2 CTPS1

5.12e-053872GO:0097268
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN1

1.02e-044872GO:0098855
GeneOntologyCellularComponentmale pronucleus

RIF1 TBP

4.72e-048872GO:0001940
DomainCTP_synthase_N

CTPS2 CTPS1

2.05e-052852IPR017456
DomainGATase1_CTP_Synthase

CTPS2 CTPS1

2.05e-052852IPR033828
DomainCTP_synthase

CTPS2 CTPS1

2.05e-052852IPR004468
DomainCTP_synth_N

CTPS2 CTPS1

2.05e-052852PF06418
DomainIon_trans_N

HCN4 HCN1

1.22e-044852IPR013621
DomainIon_trans_N

HCN4 HCN1

1.22e-044852PF08412
DomainHnRNP-L/PTB

PTBP2 PTBP1

2.03e-045852IPR006536
DomainGATase

CTPS2 CTPS1

2.03e-045852PF00117
DomainGATASE_TYPE_1

CTPS2 CTPS1

3.03e-046852PS51273
DomainGATASE

CTPS2 CTPS1

3.03e-046852IPR017926
DomainP-type_ATPase_IIC

ATP1A2 ATP12A

3.03e-046852IPR005775
Domain-

CTPS2 CTPS1

9.00e-04108523.40.50.880
DomainClass_I_gatase-like

CTPS2 CTPS1

1.31e-0312852IPR029062
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN4 HCN1

1.80e-0314852IPR003938
DomainPept_M10A_Zn_BS

MMP1 MMP7

2.07e-0315852IPR021158
DomaincNMP-bd_CS

HCN4 HCN1

2.36e-0316852IPR018488
DomainATPase_P-typ_TM_dom

ATP1A2 ATP12A

2.36e-0316852IPR023298
Domain-

ATP1A2 ATP12A

2.36e-03168521.20.1110.10
DomainATPase_P-typ_cation-transptr_C

ATP1A2 ATP12A

2.66e-0317852IPR006068
DomainCation_ATPase_C

ATP1A2 ATP12A

2.66e-0317852PF00689
DomainCation_ATPase_N

ATP1A2 ATP12A

2.99e-0318852PF00690
DomainCation_ATPase_N

ATP1A2 ATP12A

2.99e-0318852SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A2 ATP12A

3.33e-0319852IPR004014
DomainPG_binding_1

MMP1 MMP7

3.69e-0320852PF01471
DomainPeptidoglycan-bd-like

MMP1 MMP7

3.69e-0320852IPR002477
DomainSpectrin

SYNE3 TRIO

4.87e-0323852PF00435
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

RIF1 ABCF1 TTLL9 PTBP2 TLN1 NEMF BAZ1B PSME3 RBM28 PTBP1 SHOC2 CNN3 ARCN1

9.18e-09653871333742100
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

GSTM3 UAP1 MYH11 ABCF1 EPPK1 TLN1 GART SRM PSME3 ALDH1A1 PTBP1 KYNU HYDIN ARCN1

1.33e-08807871430575818
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

RIF1 TUT4 SALL1 PTBP2 SHOC2 CNN3 TOP2B TBP

4.62e-0820387822083510
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZC3H7A RIF1 ABCF1 CSNK1E NEMF SMC6 BAZ1B RBM28 PTBP1 L3MBTL3 TOP2B ARCN1

4.25e-07759871235915203
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

RIF1 EPPK1 TRIO CSNK1D CSNK1E TLN1 GART SH3KBP1 ARHGAP29 ALS2 PSME3 MGA ARCN1

4.57e-07916871332203420
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SCYL2 RIF1 SETD2 ABCF1 TLN1 GART BAZ1B SRP54 PSME3 CTPS1 CNN3 TOP2B ARCN1

5.69e-07934871333916271
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ZC3H7A RIF1 ABCF1 TLN1 GART SRM BAZ1B SRP54 PSME3 RBM28 PTBP1 CTPS1 MGA TOP2B ARCN1

1.24e-061353871529467282
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

CTPS2 CSNK1D CSNK1E MGA DMXL1

1.40e-067687527542412
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

UAP1 TUT4 CSNK1D CSNK1E HECW2 PLCB2 PSME3 MMP1 MMP7 ATP1A2 DMXL1

2.13e-06730871134857952
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZC3H7A SETD2 TUT4 TRIO CSNK1E MTR FAM3C RBM28 CTPS1 MGA PRRC1

2.21e-06733871134672954
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

FOCAD RIF1 SETD2 ADIPOR1 ACADS SQLE NEMF SMC6 ITM2C PSME3 ATP12A KYNU PRRC1

2.33e-061061871333845483
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RIF1 ABCF1 TRIO CSNK1E TLN1 GART NEMF SMC6 MTR BAZ1B PSME3 PTBP1 CTPS1 TOP2B ARCN1

2.35e-061425871530948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH11 ABCF1 NRXN2 TRIO CSNK1D HECW2 TLN1 SCN2A SH3KBP1 ITM2C BCAS1 ATP1A2 PTBP1 TNS1 ARCN1

2.47e-061431871537142655
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

GSTM3 ZC3H7A ABCF1 SYNE3 CSNK1E TLN1 SRM MTR ASCC2 BAZ1B SRP54 ITM2C RBM28 TOP2B DMXL1

3.95e-061487871533957083
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RIF1 CSNK1D TLN1 PSME3 RBM28 CTPS1 CNN3 ARCN1

4.28e-0637087822922362
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RIF1 SETD2 SALL1 PTBP2 SMC6 BAZ1B RBM28 PTBP1 SSX1 MGA L3MBTL3 TOP2B

4.55e-06954871236373674
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TUT4 ABCF1 ACADS TRIO HCN4 CSNK1E HCN1 SH3KBP1 ITM2C ATP1A2 PTBP1 SHOC2 ARCN1

5.04e-061139871336417873
Pubmed

Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.

CALB2 TRIO

6.19e-06287211050238
Pubmed

REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma.

CSNK1E PSME3

6.19e-06287229795381
Pubmed

Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.

CSNK1D CSNK1E

6.19e-06287219043076
Pubmed

Alternative splicing of brain-specific PTB defines a tissue-specific isoform pattern that predicts distinct functional roles.

PTBP2 PTBP1

6.19e-06287212213192
Pubmed

CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.

CSNK1D CSNK1E

6.19e-06287224424021
Pubmed

PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.

PTBP2 PTBP1

6.19e-06287227681424
Pubmed

SPEF2- and HYDIN-Mutant Cilia Lack the Central Pair-associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics.

SPEF2 HYDIN

6.19e-06287231545650
Pubmed

The matrix metalloproteinase-7 and pro-enzyme of metalloproteinase-1 as a potential marker for patients with rectal cancer without distant metastasis.

MMP1 MMP7

6.19e-06287225549795
Pubmed

Peripheral N- and C-terminal domains determine deactivation kinetics of HCN channels.

HCN4 HCN1

6.19e-06287217548059
Pubmed

Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells.

HCN4 HCN1

6.19e-06287221456027
Pubmed

Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.

CSNK1D CSNK1E

6.19e-0628729632646
Pubmed

Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli.

HCN4 HCN1

6.19e-06287211675786
Pubmed

[Change of matrix metalloproteinase-1 and matrix metalloproteinase-7 in serum and bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis and sarcoidosis].

MMP1 MMP7

6.19e-06287220979817
Pubmed

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.

MMP1 MMP7

6.19e-06287218447576
Pubmed

Association between promoters polymorphisms of matrix metalloproteinases and risk of digestive cancers: a meta-analysis.

MMP1 MMP7

6.19e-06287223644699
Pubmed

Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.

CSNK1D CSNK1E

6.19e-06287225404202
Pubmed

Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells.

HCN4 HCN1

6.19e-06287219135060
Pubmed

Genetic polymorphisms in Matrix Metalloproteinases -1 and -7 and susceptibility to gastric cancer: an association study and meta-analysis.

MMP1 MMP7

6.19e-06287223893803
Pubmed

Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells.

PTBP2 PTBP1

6.19e-06287221768390
Pubmed

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.

PTBP2 PTBP1

6.19e-06287217606642
Pubmed

Bladder cancer risk associated with genotypic polymorphism of the matrix metalloproteinase-1 and 7 in North Indian population.

MMP1 MMP7

6.19e-06287220826916
Pubmed

An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.

CSNK1D CSNK1E

6.19e-06287222981886
Pubmed

REGγ deficiency promotes premature aging via the casein kinase 1 pathway.

CSNK1D PSME3

6.19e-06287223766372
Pubmed

Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.

CTPS2 CTPS1

6.19e-06287220739275
Pubmed

Influence of matrix metalloproteinase gene polymorphisms in healthy North Indians compared to variations in other ethnic groups worldwide.

MMP1 MMP7

6.19e-06287220192597
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RIF1 ABCF1 EPPK1 TLN1 GART BAZ1B ITM2C RBM28 PTBP1 MGA TOP2B ARCN1

9.28e-061024871224711643
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SCYL2 SETD2 TLN1 BAZ1B PSME3 CTPS1 MGA CNN3 ARCN1

9.81e-0654987938280479
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

GSTM3 RIF1 ABCF1 EPPK1 CTPS2 TLN1 GART NEMF PBK PSME3 PTBP1 CTPS1 TOP2B ARCN1

1.07e-051415871428515276
Pubmed

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

CSNK1D CSNK1E PYGM CTPS1

1.13e-055587435945219
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

PTPN3 ABCF1 EPPK1 CSNK1D CSNK1E GART ASCC2 BAZ1B RBM28 PTBP1 CTPS1 ITIH2 ARCN1

1.44e-051257871336526897
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SCYL2 RIF1 EPPK1 PTBP2 TLN1 SRP54 PTBP1 SHOC2 ARCN1

1.56e-0558287920467437
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SALL1 TLN1 BAZ1B SRP54 PSME3 MGA L3MBTL3 TOP2B

1.60e-0544487834795231
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

GSTM3 PTPN3 EPPK1 CSNK1D CSNK1E GART MTR PYGM ALS2 PSME3 BCAS1 CTPS1 FABP4

1.80e-051284871317353931
Pubmed

MRG15 is required for pre-mRNA splicing and spermatogenesis.

PTBP2 PTBP1

1.85e-05387227573846
Pubmed

Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia.

CSNK1E FABP4

1.85e-05387227236410
Pubmed

Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.

CSNK1D CSNK1E

1.85e-05387227439882
Pubmed

HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age-dependent changes.

HCN4 HCN1

1.85e-05387233181864
Pubmed

Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.

CTPS2 CTPS1

1.85e-05387216179339
Pubmed

MMP1, 2, 3, 7, and 9 gene polymorphisms and urinary cancer risk: a meta-analysis.

MMP1 MMP7

1.85e-05387226301605
Pubmed

CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.

CSNK1D CSNK1E

1.85e-05387219805222
Pubmed

Ventricular HCN channels decrease the repolarization reserve in the hypertrophic heart.

HCN4 HCN1

1.85e-05387222652004
Pubmed

Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.

CSNK1D CSNK1E

1.85e-05387212270714
Pubmed

No association between matrix metalloproteinase (MMP)-1, MMP-3, and MMP-7 SNPs and endometrial cancer risk.

MMP1 MMP7

1.85e-05387219435861
Pubmed

Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating.

HCN4 HCN1

1.85e-05387221187420
Pubmed

Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties.

MMP1 MMP7

1.85e-0538727896811
Pubmed

Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.

CSNK1D CSNK1E

1.85e-05387222384121
Pubmed

Expression of human nPTB is limited by extreme suboptimal codon content.

PTBP2 PTBP1

1.85e-05387218335065
Pubmed

Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart.

HCN4 HCN1

1.85e-05387221945247
Pubmed

Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.

HCN4 HCN1

1.85e-05387222006928
Pubmed

The association of matrix metalloproteinases polymorphisms and interleukins in advanced age-related macular degeneration.

MMP1 MMP7

1.85e-05387229947568
Pubmed

EP3 activation facilitates bladder excitability via HCN channels on ICCs.

HCN4 HCN1

1.85e-05387228131828
Pubmed

The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.

PTBP2 PTBP1

1.85e-05387212667457
Pubmed

Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.

CSNK1D CSNK1E

1.85e-05387225724478
Pubmed

A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.

CSNK1D CSNK1E

1.85e-05387225665722
Pubmed

The splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNA.

PTBP2 TOP2B

1.85e-05387221186367
Pubmed

CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.

CSNK1D CSNK1E

1.85e-05387232321936
Pubmed

E-cadherin and metalloproteinase-1 and -7 polymorphisms in colorectal cancer.

MMP1 MMP7

1.85e-05387219634113
Pubmed

Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.

PTBP2 PTBP1

1.85e-05387227791185
Pubmed

Polypyrimidine tract binding protein 2 stabilizes phosphoglycerate kinase 2 mRNA in murine male germ cells by binding to its 3'UTR.

PTBP2 PTBP1

1.85e-05387217329592
Pubmed

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

CSNK1D CSNK1E

1.85e-05387228963394
Pubmed

Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.

CSNK1D CSNK1E

1.85e-05387231353086
Pubmed

Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.

CSNK1D CSNK1E

1.85e-0538728786104
Pubmed

Association of matrix metalloproteinases 1, 7, and 9 gene polymorphisms with genetic susceptibility to colorectal carcinoma in a Han Chinese population.

MMP1 MMP7

1.85e-05387220662554
Pubmed

PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells.

PTBP2 PTBP1

1.85e-05387226416554
Pubmed

Expression of Matrix Metalloproteinases in Intraductal Papillary Mucinous Neoplasm of the Pancreas.

MMP1 MMP7

1.85e-05387231366549
Pubmed

Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma.

MMP1 MMP7

1.85e-05387217125518
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

MPV17 SETD2 TUT4 EPPK1 GART SMC6 BAZ1B PTBP1 CTPS1 MGA

1.92e-05754871035906200
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

HCN4 HCN1 PLCB2

1.95e-052187330270038
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

ZC3H7A ABCF1 GART NEMF BAZ1B RBM28 PTBP1 TOP2B ARCN1

2.01e-0560187933658012
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

ABCF1 CTPS2 CSNK1D TBCK GART PBK ASCC2 SRP54 PSME3 PTBP1 CTPS1 CNN3 TBP

2.71e-051335871329229926
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SCYL2 RIF1 PTBP2 TLN1 GART PSME3 CTPS1 TOP2B ARCN1

3.20e-0563887933239621
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

GSTM3 SRM BAZ1B SRP54 RBM28 PTBP1 CTPS1 TOP2B ARCN1

3.31e-0564187936057605
Pubmed

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.

CSNK1D CSNK1E

3.70e-05487229784789
Pubmed

Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.

CSNK1D CSNK1E

3.70e-05487237578019
Pubmed

Functional expression of the human HCN3 channel.

HCN4 HCN1

3.70e-05487216043489
Pubmed

Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.

AHRR ANKRA2

3.70e-05487217949687
Pubmed

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.

CSNK1D CSNK1E

3.70e-05487221422228
Pubmed

Polymorphism of Matrix Metalloproteinases Genes MMP1, MMP2, MMP3, and MMP7 and the Risk of Varicose Veins of Lower Extremities.

MMP1 MMP7

3.70e-05487228944430
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SETD2 SCN2A

3.70e-05487226637798
Pubmed

MMP expression in rheumatoid inflammation: the rs11568818 polymorphism is associated with MMP-7 expression at an extra-articular site.

MMP1 MMP7

3.70e-05487223343931
Pubmed

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.

CSNK1D CSNK1E

3.70e-05487220192920
Pubmed

Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels.

HCN4 HCN1

3.70e-0548729405696
Pubmed

Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels.

HCN4 HCN1

3.70e-05487212928435
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN1

3.88e-0410542250
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_200

MYH11 SALL1 DPP10 ZFHX4 TRIO BAZ1B TOP2B

6.35e-06170877DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_200
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#1_top-relative-expression-ranked_1000

RIF1 ABCF1 SH3KBP1 MTR PSME3 ALDH1A1 MGA TNS1

1.18e-05261878gudmap_developingGonad_e12.5_epididymis_k1_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes and mesonephros_emap-3226_top-relative-expression-ranked_1000

RIF1 ABCF1 ZFHX4 CSNK1D CSNK1E GART SH3KBP1 BAZ1B PSME3 PTBP1 MGA TNS1 DMXL1

3.80e-058448713gudmap_developingGonad_e11.5_testes and mesonephros_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RIF1 TUT4 ABCF1 PTBP2 NEMF SMC6 BAZ1B TOP2B

4.15e-05311878Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD2 TUT4 TLN1 SH3KBP1 BAZ1B SRP54 TOP2B

7.57e-081848771154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 SCN2A ITM2C ALDH1A1 MMP7 CNN3

1.50e-06181876beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GSTM3 CALB2 TRIO ALS2 ALDH1A1 TNS1

1.71e-061858763fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 SH3KBP1 SMC6 CNN3 TOP2B DMXL1

1.76e-0618687626f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 SH3KBP1 SMC6 CNN3 TOP2B DMXL1

1.82e-0618787691c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 SH3KBP1 SMC6 CNN3 TOP2B DMXL1

1.82e-06187876382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

2.12e-061928767aadc7c5bd03274f9861dde2febda5c37f8afc9c
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

UAP1 SRM SRP54 FAM3C ITM2C MCEE

2.18e-061938768074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TUT4 GPC3 ANKRA2 PTBP2 TBCK MTR

2.18e-06193876e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellILEUM-non-inflamed-(8)_Pericytes|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYH11 ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

2.38e-06196876b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCellCOVID-19-Heart-Adipocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CALB2 ZFHX4 GCKR ATP1A2 FABP4

1.26e-0515387593958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

UAP1 AHRR ZFHX4 ITM2C RBM28

1.92e-05167875f4943fb5001475ddab82a0273bcbb3fa68fdd7bd
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL1 HECW2 COLGALT2 CNN3 FABP4

1.97e-05168875ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPC3 HCN4 TTLL9 SPEF2 HYDIN

2.03e-05169875fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ITM2C ALDH1A1 CNN3 ITIH2

2.15e-05171875fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TUT4 ZFHX4 TLN1 ALDH1A1 CNN3

2.60e-051788750fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell10x5'-GI_large-bowel-Mast|GI_large-bowel / Manually curated celltypes from each tissue

CALB2 GPC3 TTLL9 ALDH1A1 TNS1

2.60e-05178875d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell10x5'-GI_large-bowel-Mast-Mast_cells|GI_large-bowel / Manually curated celltypes from each tissue

CALB2 GPC3 TTLL9 ALDH1A1 TNS1

2.60e-051788758fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|390C / Donor, Lineage, Cell class and subclass (all cells)

GPC3 SRM MMP1 ATP12A CNN3

2.97e-0518387528e1fc6498aaf8f42c4d6d4fa54ffff4c546d0d1
ToppCell390C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|390C / Donor, Lineage, Cell class and subclass (all cells)

GPC3 SRM MMP1 ATP12A CNN3

2.97e-05183875667d9107af17fd076ceff6b2cbcb78f892fd62d2
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GSTM3 CALB2 TRIO ALS2 TNS1

3.21e-05186875de55471dd5c842026b409cfebf67fe32f079a011
ToppCell11.5-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

MYH11 SH3KBP1 ARHGAP29 PYGM FABP4

3.38e-05188875916971d8660fd20f616346953874e89d2cd13e88
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.47e-05189875324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.56e-0519087500fd993675faf53adf985b9316a18c8a33242029
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

3.56e-05190875136ca6da77a202874376af193a1dd71d810c76c4
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.56e-051908758cda09d761c6b504a744959d587c183f94f1beeb
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.65e-05191875beb5bb42bd53bce01339da9110d374901548793c
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.65e-051918756609d85fd2577633dcc067507304a6f9e5865ca3
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.65e-0519187580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 NRXN2 ALDH1A1 ATP1A2 TNS1

3.65e-051918755c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellCOVID-19_Moderate-Plasmablast|World / disease group, cell group and cell class

UAP1 PBK SRP54 FAM3C ITM2C

3.65e-05191875bb28703020c5296b65527094d2e5924348275e58
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TUT4 GPC3 ANKRA2 TBCK MTR

3.74e-05192875916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellCOVID-19_Moderate-Plasmablast|COVID-19_Moderate / disease group, cell group and cell class

UAP1 SRP54 FAM3C ITM2C MCEE

3.74e-0519287525c6c7a244190f82c7feab874bdec12490b7de4d
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 NRXN2 PYGM ALDH1A1 ATP1A2

3.83e-05193875fa45042d30f9cfeed10e23270a78f18551219cfa
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 NRXN2 PYGM ALDH1A1 ATP1A2

3.83e-05193875ab511ea9e09216a965b3ae5a94f8c3c1ae33d944
ToppCellfacs-Mammary_Gland|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UAP1 MYH11 SRM FAM3C CNN3

4.02e-0519587521cfcb751e548591fc8724a8329c294da6012e0f
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTLL9 SPEF2 DLEC1 BCAS1 HYDIN

4.02e-0519587579dc031258579ea328181dda33710dd897f1064a
ToppCellsevere-Plasmablast|severe / disease stage, cell group and cell class

UAP1 SRM SRP54 FAM3C ITM2C

4.02e-05195875e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GSTM3 SCN2A ITM2C MMP7 ATP12A

4.02e-051958750ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ARHGAP29 ATP1A2 TNS1 CNN3

4.22e-051978754d63a274828ebb951db78421c2823453d862cd49
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

PTPN3 ITM2C ALDH1A1 CNN3 FABP4

4.22e-05197875a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCellfacs-Heart|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM3C ITM2C ALDH1A1 ATP1A2 FABP4

4.22e-051978756a9571c0a3238b39214afdece93d7541bc8a0a70
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTM3 ZFHX4 ITM2C ALDH1A1 CNN3

4.22e-0519787505e303fff86db31f7b742324c64980eb2b9cff9a
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

UAP1 SRM SRP54 FAM3C ITM2C

4.22e-0519787599fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCellNon-neuronal-Dividing-Radial_Glia-late-42|World / Primary Cells by Cluster

ZFHX4 PBK ITM2C ATP1A2 CNN3

4.22e-051978750057aa4bce8684711b061710eab1d2b85e14e055
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

4.22e-05197875452be45f4aac8459dd860493171f5f715368d663
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTM3 GPC3 ZFHX4 PYGM ALDH1A1

4.22e-051978756b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Pericytes|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYH11 ARHGAP29 ATP1A2 TNS1 FABP4

4.22e-05197875608328608cef82adc867a449216839622253d486
ToppCellNon-neuronal-Dividing-Radial_Glia-late|World / Primary Cells by Cluster

ZFHX4 PBK ITM2C ATP1A2 CNN3

4.22e-051978759a65a54e097947601d8e382c4f4b4f5c2c1df51c
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 GPC3 SHOC2 TOP2B ARCN1

4.33e-051988752f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellsevere-Plasmablast|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UAP1 SRM FAM3C ITM2C MCEE

4.33e-051988750b1620ad4352ee5d599a72931aaceab4ca407498
ToppCellCOVID_vent-Lymphocytic-Plasma_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

UAP1 SRM SRP54 FAM3C ITM2C

4.33e-05198875e84c5f712e1dea548d0e2aba6625598f9671d3a0
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTM3 ZFHX4 ITM2C ALDH1A1 CNN3

4.33e-05198875cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 GPC3 SHOC2 TOP2B ARCN1

4.33e-05198875f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-B-Plasmablast|COVID-19_Severe / Disease, condition lineage and cell class

UAP1 SRM SRP54 FAM3C ITM2C

4.43e-05199875e6422b65e22e5aa8dfaebdae5be76dd78b978604
ToppCellsevere-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UAP1 PBK FAM3C ITM2C MCEE

4.43e-051998756ee4c2e6049860071169366b7e662d5c1a3cc54b
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 GPC3 PTBP1 TOP2B ARCN1

4.43e-051998758d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPC3 ZFHX4 TRIO ALDH1A1 CNN3

4.43e-05199875bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYH11 ITM2C ATP1A2 CTPS1 TNS1

4.43e-05199875056a28c36cd58dc695a5ae6f29b62135d6aad819
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYH11 PYGM ITM2C ATP1A2 TNS1

4.43e-05199875534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

4.43e-05199875bd9b36dcf61eaa628ce1b70d21c5783b64c29e8f
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 ATP1A2 TNS1 CNN3 FABP4

4.43e-05199875e751eb67510f8a5842dcfed44134160919cdb713
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TTLL9 HCN1 ITM2C ATP1A2 FABP4

4.43e-051998754e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgG_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

UAP1 SRM SRP54 FAM3C ITM2C

4.54e-05200875fee909730133ec9875e14f7deed2a351dd21dba4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte|3m / Sample Type, Dataset, Time_group, and Cell type.

SALL1 ZFHX4 ITM2C ATP1A2 CNN3

4.54e-0520087598d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SALL1 ZFHX4 PBK ATP1A2 CNN3

4.54e-0520087549197316231e45f8c9f007f55b036600f7195922
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

ZFHX4 NRXN2 TRIO CSNK1E HECTD4

4.54e-05200875c92e4fc0442404481fcac623d691dae6215b852d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPC3 ARHGAP29 FAM3C ITM2C MMP7

4.54e-05200875d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial-RG|3_mon / Sample Type, Dataset, Time_group, and Cell type.

SALL1 ZFHX4 PBK ATP1A2 CNN3

4.54e-05200875dea7928d6ceb7a347f56c6d0c9c7a56b7a2c0a80
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPC3 ARHGAP29 FAM3C ITM2C MMP7

4.54e-0520087533b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Macroglial|3m / Sample Type, Dataset, Time_group, and Cell type.

SALL1 ZFHX4 ITM2C ATP1A2 CNN3

4.54e-0520087538b51f337e183011e3ff32997ec26d8a424c6b78
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_cell-B_naive|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SCYL2 PLCB2 MGA KYNU

4.61e-0510187486acaa2502f61baa714ae988b73e3e73a71e897e
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

CALB2 ZFHX4 ALDH1A1 BCAS1

7.65e-0511587418174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

PTPN3 ZFHX4 HCN4 GCKR

7.92e-051168745ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 ATP12A SERPINA6 HYDIN

1.87e-0414587496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPC3 FAM3C ATP12A FABP4

1.87e-0414587407acbf086cffce0628accf078d31bf190f803988
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GART DLEC1 SERPINA6 HYDIN

2.13e-0415087453de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GART DLEC1 SERPINA6 HYDIN

2.13e-04150874e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 DLEC1 ATP12A HYDIN

2.41e-041558745f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CALB2 SALL1 PYGM L3MBTL3

2.41e-0415587499e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL9 DLEC1 ATP12A HYDIN

2.41e-041558740944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HECW2 MMP7 PRRC1 ARCN1

2.54e-041578744183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell10x5'-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

MYH11 CALB2 DPP10 ALS2

2.66e-04159874c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 ZFHX4 HCN1 HYDIN

2.73e-04160874c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 GCKR ALDH1A1 SERPINA6

2.73e-04160874c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 ZFHX4 HCN1 HYDIN

2.73e-0416087425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPC3 PYGM MMP1 MMP7

2.79e-041618740d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 PYGM ITM2C ALDH1A1

2.92e-04163874e526104a3a574ee860078ce7c049e7fec9443f37
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SPEF2 DLEC1 BCAS1 HYDIN

2.99e-041648740e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellCOVID-19-lung-Mesothelial|COVID-19 / Disease (COVID-19 only), tissue and cell type

CALB2 DPP10 ZFHX4 DLEC1

2.99e-0416487483303e2ba52008391b8dc3fae8225ab5bcb20063
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 SQLE ALDH1A1 ITIH2

3.06e-04165874d449a568664a81d9b5538e8f409301448a32ac37
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SETD2 HECTD4 MTR MGA

3.13e-0416687432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell10x5'-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

CALB2 ALS2 ALDH1A1 TNS1

3.28e-04168874650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP10 ZFHX4 SCN2A HYDIN

3.28e-04168874e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UAP1 TUT4 ITM2C ALDH1A1

3.28e-0416887474d6dbf9295933acdee785af9b73a94377d15412
ToppCell10x5'-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

CALB2 ALS2 ALDH1A1 TNS1

3.28e-04168874e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 GCKR ALDH1A1 ITIH2

3.28e-04168874b98af4043dfa5dfa4413e482879fad88de484675
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP10 ZFHX4 SCN2A HYDIN

3.28e-04168874b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 GCKR ALDH1A1 ITIH2

3.28e-04168874073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM3 GCKR ALDH1A1 ITIH2

3.35e-04169874f195467438c589f87224bde7da720dea072d110c
Diseasesick sinus syndrome (implicated_via_orthology)

HCN4 HCN1

2.51e-053862DOID:13884 (implicated_via_orthology)
Diseasetotal blood protein measurement

PTPN3 SETD2 ACADS SH3KBP1 ARHGAP29 GCKR KYNU HYDIN

5.08e-05449868EFO_0004536
DiseaseMalignant neoplasm of breast

RIF1 SETD2 CSNK1D SMC6 ARHGAP29 MTR DLEC1 COLGALT2 MMP1 TNS1 L3MBTL3 FABP4

6.50e-0510748612C0006142
Diseaseattention deficit hyperactivity disorder, bipolar disorder

SCN2A ASCC2 BCAS1

1.01e-0431863EFO_0003888, MONDO_0004985
DiseaseFamilial benign neonatal epilepsy

SCN2A ATP1A2

1.25e-046862C0220669
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A2 ATP12A

1.75e-047862DOID:0060178 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Najm type (implicated_via_orthology)

CSNK1D CSNK1E

1.75e-047862DOID:0060807 (implicated_via_orthology)
Diseasenon-high density lipoprotein cholesterol measurement

PTPN3 SMC6 ITM2C GCKR BCAS1 PTBP1 L3MBTL3 HYDIN ARCN1

2.34e-04713869EFO_0005689
Diseasespleen volume

HECTD4 ASCC2 L3MBTL3

2.71e-0443863EFO_0600047
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

HCN1 SCN2A

2.98e-049862C3502809
Diseaseserum gamma-glutamyl transferase measurement

PTPN3 SETD2 SALL1 ACADS TLN1 HECTD4 BAZ1B GCKR PTBP1 L3MBTL3

3.27e-049148610EFO_0004532
Diseasethoracic aortic aneurysm (is_implicated_in)

MYH11 MMP1

4.54e-0411862DOID:14004 (is_implicated_in)
Diseasenervous system disease (implicated_via_orthology)

ATP1A2 ATP12A

5.44e-0412862DOID:863 (implicated_via_orthology)
Diseasealcohol consumption measurement, alcohol drinking

HECTD4 GCKR

5.44e-0412862EFO_0004329, EFO_0007878
Diseasefactor VII measurement

FOCAD SCN2A GCKR

5.62e-0455863EFO_0004619
Diseaseliver cirrhosis (implicated_via_orthology)

FOCAD MMP1

6.41e-0413862DOID:5082 (implicated_via_orthology)
Diseasecolonic neoplasm, overall survival

DPP10 HCN1

7.47e-0414862EFO_0000638, EFO_0004288
DiseaseC-reactive protein measurement

MPV17 PTPN3 SALL1 ACADS BAZ1B PSME3 GCKR PTBP1 SERPINA6 L3MBTL3 TOP2B

7.50e-0412068611EFO_0004458
Diseasehepatoblastoma (is_marker_for)

SALL1 GPC3

8.60e-0415862DOID:687 (is_marker_for)
Diseasediet measurement

SCYL2 TRIO PTBP2 HECW2 HCN1 SCN2A ASCC2 BAZ1B GCKR SHOC2

9.48e-0410498610EFO_0008111
Diseaseresting heart rate

MYH11 EPPK1 HCN4 GCKR

9.62e-04149864EFO_0004351
DiseaseTremor, Rubral

HCN1 ARCN1

9.81e-0416862C0750940
DiseaseAtaxia, Appendicular

HCN1 ARCN1

9.81e-0416862C0750937
DiseaseAtaxia, Motor

HCN1 ARCN1

9.81e-0416862C0278161
DiseaseAtaxia, Sensory

HCN1 ARCN1

9.81e-0416862C0240991
DiseaseAbnormal coordination

HCN1 ARCN1

9.81e-0416862C0520966
DiseaseAtaxia, Truncal

HCN1 ARCN1

9.81e-0416862C0427190
Diseaseprotein C measurement

BAZ1B GCKR

1.11e-0317862EFO_0004633
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

SETD2 TRIO

1.11e-0317862DOID:0060307 (is_implicated_in)
Diseasecystatin C measurement

SALL1 HECTD4 SRM BAZ1B GCKR BCAS1

1.16e-03402866EFO_0004617
Diseaseepilepsy (implicated_via_orthology)

TRIO SCN2A ATP1A2 ATP12A

1.34e-03163864DOID:1826 (implicated_via_orthology)
DiseaseHypertriglyceridemia

BAZ1B GCKR

1.39e-0319862EFO_0004211
Diseaseselenium measurement, response to dietary selenium supplementation

ZC3H7A TRIO

1.54e-0320862EFO_0006331, EFO_0600021
Diseasehaptoglobin measurement

CALB2 HYDIN

1.70e-0321862EFO_0004640
Diseasealcohol drinking

HECTD4 GCKR ALDH1A1

1.73e-0381863EFO_0004329
Diseaseanxiety disorder (implicated_via_orthology)

HCN1 SCN2A

1.87e-0322862DOID:2030 (implicated_via_orthology)
DiseaseAutism Spectrum Disorders

DPP10 NRXN2 NEMF

1.99e-0385863C1510586
Diseasenephrotic syndrome (implicated_via_orthology)

MPV17 SH3KBP1

2.22e-0324862DOID:1184 (implicated_via_orthology)
DiseaseAtaxia

HCN1 ARCN1

2.41e-0325862C0004134
DiseaseNeurodevelopmental Disorders

SETD2 TRIO SCN2A

2.57e-0393863C1535926

Protein segments in the cluster

PeptideGeneStartEntry
TMQFQGKLKFLFGQK

AHRR

241

A9YTQ3
GSQVVKLPFINFMKT

ARSK

51

Q6UWY0
GQKPLFKNLDFGIDM

ABCF1

636

Q8NE71
FPAAQVKKMGGLGLL

ACADS

66

P16219
NFLVMGGFQLLAKPA

ALS2

791

Q96Q42
QASVIKKFLQGFMAP

BAZ1B

1101

Q9UIG0
VLFGKGNSPLLQKMI

ASCC2

166

Q9H1I8
GLNFLAIKGPELMNK

SPATA5

686

Q8NB90
IFGPVQQIMKFKSLD

ALDH1A1

401

P00352
QGVAMGMKFILPNRF

ANKRA2

46

Q9H9E1
KLFMYGPLAGKVQDQ

DMXL1

1161

Q9Y485
GSKFFMTVPVKQGGR

DPP10

381

Q8N608
GKMRGFGFVQFKNLL

RBM28

151

Q9NW13
FGFNLKGGVDQKMPL

PTPN3

521

P26045
SFPYNKNGFKVGMKL

L3MBTL3

256

Q96JM7
DLRAVGLKKGMFFNP

HECW2

191

Q9P2P5
FKMASGAANVVGPKI

FAM3C

71

Q92520
PLQEKVVFGMFFLGA

ADIPOR1

166

Q96A54
EMQKFFGLPITGMLN

MMP7

61

P09237
SPIAGFLQKNKAGGM

MCEE

106

Q96PE7
TTGSFMIRGKKNFLP

NEMF

631

O60524
FVMSKVGALQQKIPG

MGA

1541

Q8IWI9
KFSPKAHGLIGQFMQ

ITIH2

851

P19823
KVFGNFPKLIMTQVS

GPC3

206

P51654
TPEIVKFLKQMVGGF

ATP12A

101

P54707
PDNFLMGLGKKGNLV

CSNK1D

131

P48730
IGGLSKNMFSNLPKL

NRXN2

1041

Q9P2S2
PGQLKQFSMFLGKFS

GSTM3

136

P21266
ALPKFAIRGMLKTFG

HECTD4

2356

Q9Y4D8
MLQPGVNKFSLRMFG

HCN4

221

Q9Y3Q4
MVKISFQPAVAGIKG

ITM2C

1

Q9NQX7
FNQLMKGLGQKPLYT

GCKR

121

Q14397
KMNSKNLGVIFGPSL

ARHGAP29

836

Q52LW3
VFQQGMKNKILIFGL

ATP1A2

941

P50993
MLQPGVNKFSLRMFG

HCN1

101

O60741
GLVNMFKGFQSKVLP

HYDIN

16

Q4G0P3
FVGFLMKNAPQFKAN

SQLE

306

Q14534
PVQENFLLKFQGMKL

CALB2

181

P22676
VGFATRKVAGMAKPN

FABP4

26

P15090
GAQKLVGANPFGKML

COLGALT2

506

Q8IYK4
FFKGLGPKRMLDAQV

BCAS1

556

O75363
KNVGFSVGRFCIMPK

DLEC1

501

Q9Y238
MSEQFKAKFPFGGLL

SALL1

666

Q9NSC2
GTVFFILPDKGKMNT

SERPINA6

261

P08185
GLLAAFPKLMNTGKQ

ARCN1

31

P48444
QGKTVAGIPNFILKM

FOCAD

806

Q5VW36
FLDMAPKGIIGNKAF

SPEF2

1476

Q9C093
FQNIMKMGPFSQILG

SRP54

336

P61011
VMFNGKKLPVNGFRS

TOP2B

276

Q02880
PFGKVTNILMLKGKN

PTBP2

81

Q9UKA9
KMVFTNNIPKSGFLI

SYNE3

766

Q6ZMZ3
QMQEFFGLKVTGKPD

MMP1

66

P03956
GFRSGAPMIKKIAFI

RIF1

281

Q5UIP0
SGSQIPLFQAMKKGL

EPPK1

371

P58107
DLFGAGKMFLPQVIK

MTR

721

Q99707
NGKTGMFPSNFIKEL

SH3KBP1

141

Q96B97
QKKPFLGVCLGMQLA

CTPS1

391

P17812
VAGGPSFIIQFLKMQ

SHOC2

561

Q9UQ13
SLGTVMYAVFNKGKP

SCYL2

251

Q6P3W7
LKKMLLDQGGFAPCF

MPV17

86

P39210
FIKGVAGNPMVKSVL

PRRC1

216

Q96M27
LGFKVTLPPFMCNKQ

SSX1

61

Q16384
IGNFIKAIQAYGMKP

CNN3

86

Q15417
LAANAIPKGFMDGKQ

MYH11

731

P35749
FQGTKVFVMPNGMLK

PSME3

96

P61289
KKIPFLGVCLGMQLA

CTPS2

391

Q9NRF8
KFKINIGKPFMINQG

ZFHX4

2941

Q86UP3
NKFFVPRTVMIGGKA

PYGM

596

P11217
FPAKFLDFKIQNMVG

TBP

246

P20226
QSFLQPGGKMVAAAK

TLN1

991

Q9Y490
FLTGQKMLPKHLQGG

SPATA31D1

1556

Q6ZQQ2
GLLSGSIKMNNKPLF

TNS1

171

Q9HBL0
PANKFQGMVFDFVTK

SCN2A

1516

Q99250
MLGPFKFGSNVNFVV

SMC6

61

Q96SB8
QVSKKFLPGMAIGYS

SRM

131

P19623
QKLGFGTGVNVYLMK

PBK

36

Q96KB5
GPYTAMLQNFKGKVI

TBCK

831

Q8TEA7
SEGKIPVKNFFQMFP

PLCB2

161

Q00722
GIMLTKNGPKVLEFN

GART

276

P22102
LKKENVIFFQQGMLP

UAP1

186

Q16222
QKTGFIKGPMFKGVA

SETD2

36

Q9BYW2
GNQIMPGFLNMKIKF

ZC3H7A

696

Q8IWR0
MKPVARSQGKGIFLF

TTLL9

166

Q3SXZ7
IMKAFINGRKLFGTP

TUT4

1251

Q5TAX3
PFGKVTNLLMLKGKN

PTBP1

81

P26599
GFSMPGFLFKNSIKV

TRIO

2206

O75962
PDNFLMGLGKKGNLV

CSNK1E

131

P49674
FLGNSLGLQPKMVKT

KYNU

71

Q16719