Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-directed DNA polymerase activity	POLA1 REV3L POLQ	9.77e-05	25	72	3	GO:0003887
GeneOntologyMolecularFunction	nucleotidyltransferase activity	PARP4 POLA1 REV3L POLQ PAPOLG	2.22e-04	152	72	5	GO:0016779
GeneOntologyMolecularFunction	DNA polymerase activity	POLA1 REV3L POLQ	3.46e-04	38	72	3	GO:0034061
GeneOntologyBiologicalProcess	DNA-templated DNA replication	WDHD1 BRCA2 POLA1 REV3L MCM10 RRM1 POLQ	2.91e-06	178	72	7	GO:0006261
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	POLA1 REV3L RRM1 POLQ	2.36e-05	48	72	4	GO:0000731
HumanPheno	Leukonychia	DSP PEX1 PLCD1 KIF11	4.37e-07	14	25	4	HP:0001820
HumanPheno	Abnormality of nail color	DSP PEX1 PLCD1 KIF11	1.67e-06	19	25	4	HP:0100643
Domain	RNaseH-like_dom	REXO4 SUPT6H POLA1 REV3L POLQ	5.97e-06	69	70	5	IPR012337
Domain	-	REXO4 POLA1 REV3L POLQ	2.86e-05	47	70	4	3.30.420.10
Domain	-	POLA1 REV3L	4.14e-05	3	70	2	3.90.1600.10
Domain	DNA_pol_palm_dom	POLA1 REV3L	4.14e-05	3	70	2	IPR023211
Domain	DNA_POLYMERASE_B	POLA1 REV3L	4.14e-05	3	70	2	PS00116
Domain	DNA-dir_DNA_pol_B_CS	POLA1 REV3L	4.14e-05	3	70	2	IPR017964
Domain	DNA-dir_DNA_pol_B	POLA1 REV3L	8.27e-05	4	70	2	IPR006172
Domain	DNA-dir_DNA_pol_B_exonuc	POLA1 REV3L	8.27e-05	4	70	2	IPR006133
Domain	DNA-dir_DNA_pol_B_multi_dom	POLA1 REV3L	8.27e-05	4	70	2	IPR006134
Domain	DNA_pol_B_exo1	POLA1 REV3L	8.27e-05	4	70	2	PF03104
Domain	DNA_pol_B	POLA1 REV3L	8.27e-05	4	70	2	PF00136
Domain	POLBc	POLA1 REV3L	8.27e-05	4	70	2	SM00486
Domain	Plectin_repeat	DSP PPL	2.87e-04	7	70	2	IPR001101
Domain	Plectin	DSP PPL	2.87e-04	7	70	2	PF00681
Domain	PLEC	DSP PPL	2.87e-04	7	70	2	SM00250
Domain	-	ELOA IWS1	1.05e-03	13	70	2	1.20.930.10
Domain	TFIIS_N	ELOA IWS1	1.05e-03	13	70	2	PS51319
Domain	Med26	ELOA IWS1	1.05e-03	13	70	2	PF08711
Domain	TFIIS_N	ELOA IWS1	1.22e-03	14	70	2	IPR017923
Domain	Znf_FYVE_PHD	KDM3A KMT2C RSF1 KAT6B	2.26e-03	147	70	4	IPR011011
Domain	PHD	KMT2C RSF1 KAT6B	2.81e-03	75	70	3	PF00628
Domain	Znf_PHD-finger	KMT2C RSF1 KAT6B	3.25e-03	79	70	3	IPR019787
Domain	tRNA-bd_arm	DSP RPRD2	3.62e-03	24	70	2	IPR010978
Pubmed	Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication.	WDHD1 POLA1 MCM10	8.51e-09	3	72	3	17761813
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ELOA AP2A2 BRCA2 SUPT6H RPRD2 REV3L MCM10 POLQ	2.05e-08	222	72	8	37071664
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	SMAP1 AP2A2 MYO1E VWA8 DSP CEBPZ SUPT6H POLA1 ANP32A LARS1 RRM1 NUDC ACBD3 GOLGB1 KIF11 IWS1	2.48e-08	1415	72	16	28515276
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	KMT2C POLQ GOLGB1 PPL KIF11 PHTF1 PAPOLG	2.62e-07	208	72	7	33230847
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ELOA AP2A2 DSP CEBPZ LMLN RSF1 FUNDC2 TMSB10 POLQ GOLGB1 PPL KIF11 PHTF1 PTK7	1.31e-06	1442	72	14	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A KMT2C VWA8 SUPT6H HS2ST1 SLMAP LARS1 RPRD2 KAT6B	1.48e-06	529	72	9	14621295
Pubmed	Proteomic analysis of SET-binding proteins.	KDM3A SUPT6H ANP32A ANP32D	1.61e-06	41	72	4	17309103
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	AP2A2 MYO1E VWA8 CEBPZ POLA1 HS2ST1 LTN1 PEX1 FUNDC2 GOLGB1	3.45e-06	754	72	10	33060197
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	C11orf98 REXO4 AP2A2 DSP CEBPZ MYO9B POLA1 RSF1 LTN1 LARS1 MCM10 RRM1 KIF11	3.69e-06	1353	72	13	29467282
Pubmed	Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication.	POLA1 MCM10	4.23e-06	2	72	2	17699597
Pubmed	Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis.	DSP PPL	4.23e-06	2	72	2	34815391
Pubmed	Physical interactions between Mcm10, DNA, and DNA polymerase alpha.	POLA1 MCM10	4.23e-06	2	72	2	19608746
Pubmed	Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain.	REV3L POLQ	4.23e-06	2	72	2	32838755
Pubmed	Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin.	ACBD3 GOLGB1	4.23e-06	2	72	2	11590181
Pubmed	Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.	SUPT6H IWS1	4.23e-06	2	72	2	30208029
Pubmed	BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.	BRCA2 MCM10	1.27e-05	3	72	2	34645815
Pubmed	Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation.	RAG1 PAK2	1.27e-05	3	72	2	36103814
Pubmed	Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage.	ANP32A ANP32D	1.27e-05	3	72	2	36370958
Pubmed	RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells.	WDHD1 MCM10	1.27e-05	3	72	2	25602958
Pubmed	Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses.	RAG1 TLR5	1.27e-05	3	72	2	22323829
Pubmed	Modulation of oncogenic potential by alternative gene use in human prostate cancer.	ANP32A ANP32D	1.27e-05	3	72	2	10086381
Pubmed	The expression and distributions of ANP32A in the developing brain.	ANP32A ANP32D	1.27e-05	3	72	2	25866766
Pubmed	Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci.	ANP32A ANP32D	1.27e-05	3	72	2	8970164
Pubmed	Low Polymerase Activity Attributed to PA Drives the Acquisition of the PB2 E627K Mutation of H7N9 Avian Influenza Virus in Mammals.	ANP32A ANP32D	1.27e-05	3	72	2	31213560
Pubmed	A transgenic insertion causing cryptorchidism in mice.	BRCA2 RXFP2	1.27e-05	3	72	2	11353515
Pubmed	Regulation of neonatal IgA production by the maternal microbiota.	RAG1 TLR5	1.27e-05	3	72	2	33619092
Pubmed	PHAPI/pp32 suppresses tumorigenesis by stimulating apoptosis.	ANP32A ANP32D	1.27e-05	3	72	2	19121999
Pubmed	Tumor suppression and potentiation by manipulation of pp32 expression.	ANP32A ANP32D	1.27e-05	3	72	2	11360199
Pubmed	ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia.	ANP32A ANP32D	1.27e-05	3	72	2	29269781
Pubmed	PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A.	ANP32A ANP32D	1.27e-05	3	72	2	38421166
Pubmed	The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells.	SUPT6H IWS1	1.27e-05	3	72	2	25590759
Pubmed	ANP32A regulates histone H3 acetylation and promotes leukemogenesis.	ANP32A ANP32D	1.27e-05	3	72	2	29467488
Pubmed	Identification of sequences required for inhibition of oncogene-mediated transformation by pp32.	ANP32A ANP32D	1.27e-05	3	72	2	10400610
Pubmed	Generation and characterization of LANP/pp32 null mice.	ANP32A ANP32D	1.27e-05	3	72	2	15060138
Pubmed	Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin.	DSP PPL	1.27e-05	3	72	2	9412476
Pubmed	Inhibition of Histone Acetylation by ANP32A Induces Memory Deficits.	ANP32A ANP32D	1.27e-05	3	72	2	29782322
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	WDHD1 BRCA2 RSF1 RPRD2 POLQ	1.93e-05	157	72	5	30686591
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ELOA WDHD1 CEBPZ FUNDC2 RPRD2 MCM10 TEX9 ACBD3 PAPOLG	2.03e-05	733	72	9	34672954
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ELOA DSP RSF1 LARS1 PAK2 RPRD2 NUDC ACBD3 GOLGB1 KIF11	2.21e-05	934	72	10	33916271
Pubmed	The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.	SUPT6H IWS1	2.53e-05	4	72	2	19141475
Pubmed	Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa.	ANP32A ANP32D	2.53e-05	4	72	2	10657254
Pubmed	Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.	ANP32A ANP32D	2.53e-05	4	72	2	28472990
Pubmed	Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex.	ANP32A ANP32D	2.53e-05	4	72	2	19136565
Pubmed	Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis.	ANP32A ANP32D	2.53e-05	4	72	2	12807913
Pubmed	ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response.	ANP32A ANP32D	2.53e-05	4	72	2	32231671
Pubmed	The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1.	ANP32A ANP32D	2.53e-05	4	72	2	9353121
Pubmed	Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus.	ANP32A ANP32D	2.53e-05	4	72	2	37074204
Pubmed	Generation and characterization of the Anp32e-deficient mouse.	ANP32A ANP32D	2.53e-05	4	72	2	21049064
Pubmed	ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.	ANP32A ANP32D	2.53e-05	4	72	2	30209244
Pubmed	Cpd-1 null mice display a subtle neurological phenotype.	ANP32A ANP32D	2.53e-05	4	72	2	20844742
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	BRCA2 VWA8 DSP SUPT6H LARS1 PEX1 NUDC ACBD3 GOLGB1	2.54e-05	754	72	9	35906200
Pubmed	Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.	BRCA2 REV3L POLQ	2.69e-05	28	72	3	19661089
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A ELOA WDHD1 DSP KAT6B PPL ALPI IWS1 PAPOLG	3.11e-05	774	72	9	15302935
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	DSP LARS1 RRM1 GOLGB1 KIF11	3.61e-05	179	72	5	36261009
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	C11orf98 AP2A2 MYO1E VWA8 CEBPZ ANP32A LTN1 LARS1 RRM1 NUDC ALPI IWS1	3.73e-05	1440	72	12	30833792
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KDM3A ELOA REXO4 POLA1 RSF1 MCM10 IWS1 PAPOLG	3.73e-05	608	72	8	36089195
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SMAP1 KDM3A BRCA2 PAK2 MCM10 NUDC PAPOLG	3.80e-05	444	72	7	34795231
Pubmed	Structural bases for recognition of Anp32/LANP proteins.	ANP32A ANP32D	4.21e-05	5	72	2	18410380
Pubmed	Iws1 and Spt6 Regulate Trimethylation of Histone H3 on Lysine 36 through Akt Signaling and are Essential for Mouse Embryonic Genome Activation.	SUPT6H IWS1	4.21e-05	5	72	2	30846735
Pubmed	The Anp32 family of proteins containing leucine-rich repeats.	ANP32A ANP32D	4.21e-05	5	72	2	15895553
Pubmed	Relatively frequent switching of transcription start sites during cerebellar development.	ANP32A ANP32D	4.21e-05	5	72	2	28610618
Pubmed	The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.	ANP32A ANP32D	4.21e-05	5	72	2	17557114
Pubmed	LANP mediates neuritic pathology in Spinocerebellar ataxia type 1.	ANP32A ANP32D	4.21e-05	5	72	2	22884877
Pubmed	Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development.	ANP32A ANP32D	4.21e-05	5	72	2	21636789
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	SUPT6H RSF1 NKTR ACBD3 IWS1	4.57e-05	188	72	5	29721183
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	WDHD1 SUPT6H POLA1 LARS1 RRM1 NUDC ACBD3 KIF11	5.23e-05	638	72	8	33239621
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KMT2C WDHD1 CEBPZ SUPT6H RSF1 NUDC IWS1	5.37e-05	469	72	7	27634302
Pubmed	Chromosomal location of three unconventional myosin heavy chain genes in the mouse.	MYO1E MYO9B	6.31e-05	6	72	2	8954808
Pubmed	The mouse orthologue of the human ionotropic glutamate receptor-like gene (GRINL1A) maps(1) to mouse chromosome 9.	ANP32A ANP32D	6.31e-05	6	72	2	12063408
Pubmed	Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentin.	DSP PPL	6.31e-05	6	72	2	12366696
Pubmed	A human MAP kinase interactome.	KMT2C DSP DIAPH2 NAV3 PAK2 NKTR GOLGB1	6.71e-05	486	72	7	20936779
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	SMAP1 LARS1 DIAPH2 NUDC ACBD3 GOLGB1	7.46e-05	339	72	6	37232246
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	AP2A2 WDHD1 MYO1E DSP POLA1 RPRD2	7.58e-05	340	72	6	24332808
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	DSP CEBPZ PPL KIF11 IWS1	7.71e-05	210	72	5	16565220
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	KDM3A WDHD1 POLA1 LARS1 PEX1 RPRD2 GOLGB1	8.62e-05	506	72	7	30890647
Pubmed	Exons 5-15 of kazrin are dispensable for murine epidermal morphogenesis and homeostasis.	DSP PPL	8.82e-05	7	72	2	22513779
Pubmed	Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.	BRCA2 POLA1	8.82e-05	7	72	2	28757209
Pubmed	The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.	SUPT6H IWS1	8.82e-05	7	72	2	17234882
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	KMT2C WDHD1 POLA1 RSF1 RPRD2 NKTR MCM10 NUDC	8.93e-05	689	72	8	36543142
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KMT2C AP2A2 GNPTAB RPRD2 KAT6B	1.07e-04	225	72	5	12168954
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	WDHD1 MYO1E GOLGB1 PPL	1.08e-04	118	72	4	30979931
Pubmed	Gene essentiality and synthetic lethality in haploid human cells.	AP2A2 HS2ST1 SLMAP LARS1 RPRD2	1.16e-04	229	72	5	26472760
Pubmed	Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.	WDHD1 MCM10	1.17e-04	8	72	2	19805216
Pubmed	DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ.	POLA1 REV3L	1.17e-04	8	72	2	22465957
Pubmed	Impaired motor coordination in mice that lack punc.	ANP32A ANP32D	1.17e-04	8	72	2	11486040
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	ELOA PARP4 MYO9B GNPTAB LARS1 NAV3 PLCD1 PPL	1.35e-04	732	72	8	34732716
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3A KMT2C DSP CEBPZ PAK2 RPRD2 NUDC	1.43e-04	549	72	7	38280479
Pubmed	Compartmentalized control of skin immunity by resident commensals.	RAG1 TLR5	1.51e-04	9	72	2	22837383
Pubmed	Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex.	ANP32A ANP32D	1.51e-04	9	72	2	11830591
Pubmed	Genetic polymorphisms in double-strand break DNA repair genes associated with risk of oral premalignant lesions.	RAG1 BRCA2	1.51e-04	9	72	2	18579371
Pubmed	Plakin proteins are coordinately cleaved during apoptosis but preferentially through the action of different caspases.	DSP PPL	1.51e-04	9	72	2	15500642
Pubmed	MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice.	RAG1 TLR5	1.51e-04	9	72	2	22466646
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3A ELOA PAK2 RPRD2	1.57e-04	130	72	4	35545047
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ELOA AP2A2 VWA8 SUPT6H HS2ST1 LTN1 KIF11	1.61e-04	560	72	7	35241646
Pubmed	TNF is required for TLR ligand-mediated but not protease-mediated allergic airway inflammation.	RAG1 TLR5	1.88e-04	10	72	2	28758900
Pubmed	Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.	TLR5 IRAK4 PAK2 PLCD1	2.15e-04	141	72	4	20056178
Pubmed	De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair.	SUPT6H RSF1	2.30e-04	11	72	2	31045206
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM3A KMT2C KAT6B	2.30e-04	57	72	3	18022353
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	MYO1E ANP32A LARS1 RRM1 KIF11 IWS1	2.45e-04	422	72	6	27342126
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ELOA REXO4 MYO1E DSP CEBPZ SLMAP LARS1 NUDC PPL KIF11	2.57e-04	1257	72	10	36526897
Interaction	NUP43 interactions	KDM3A REXO4 BRCA2 DSP CEBPZ SUPT6H POLA1 LMLN RSF1 NKTR NUDC IWS1	1.46e-06	625	70	12	int:NUP43
Interaction	SNRNP40 interactions	KDM3A REXO4 BRCA2 MYO1E CEBPZ SUPT6H POLA1 RSF1 TMSB10 NKTR PAPOLG	1.15e-05	637	70	11	int:SNRNP40
Interaction	SOX2 interactions	ELOA KMT2C PARP4 REXO4 MYO1E DSP MYO9B GNPTAB ANP32A LARS1 NAV3 PAK2 PLCD1 SLFN5 KAT6B PPL	2.26e-05	1422	70	16	int:SOX2
Interaction	KCNA3 interactions	KMT2C DSP LARS1 PAK2 RRM1 POLQ NUDC GOLGB1 PPL KIF11 PHTF1 PAPOLG	4.15e-05	871	70	12	int:KCNA3
Interaction	H3-3A interactions	KDM3A ELOA KMT2C REXO4 POLA1 RSF1 MCM10 NUDC KIF11 IWS1 PAPOLG	5.08e-05	749	70	11	int:H3-3A
GeneFamily	DNA polymerases	POLA1 REV3L POLQ	2.81e-05	23	47	3	535
GeneFamily	ANP32 acidic nuclear phosphoproteins	ANP32A ANP32D	6.58e-05	5	47	2	27
GeneFamily	EF-hand domain containing\|Plakins	DSP PPL	1.83e-04	8	47	2	939
GeneFamily	PHD finger proteins	KMT2C RSF1 KAT6B	1.65e-03	90	47	3	88
Coexpression	HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	WDHD1 BRCA2 POLA1 ANP32A MCM10 ANP32D RRM1 NUDC	1.08e-08	155	72	8	MM1259
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	FAP WDHD1 CEBPZ GNPTAB RSF1 SLMAP NKTR REV3L POLQ GOLGB1 KIF11 IWS1	2.13e-07	656	72	12	M18979
Coexpression	HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	WDHD1 BRCA2 POLA1 ANP32A MCM10 RRM1 NUDC	2.16e-07	153	72	7	M5588
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	BRCA2 MYO1E POLA1 HS2ST1 NKTR RRM1	1.78e-05	198	72	6	M3195
Coexpression	GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	SMAP1 AP2A2 MYO1E GNPTAB RPRD2 ACBD3	1.83e-05	199	72	6	M9498
Coexpression	GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN	ELOA ENPP3 ANP32A LTN1 PLCD1 DUS1L	1.83e-05	199	72	6	M5092
Coexpression	GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP	KDM3A MYO9B LTN1 PAK2 REV3L KAT6B	1.88e-05	200	72	6	M3277
Coexpression	PUJANA_BRCA2_PCC_NETWORK	RAG1 WDHD1 BRCA2 POLA1 PEX1 PAK2 RRM1 KIF11	2.20e-05	426	72	8	M9516
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	KMT2C WDHD1 BRCA2 CEBPZ SUPT6H RSF1 LARS1 PAK2 SLFN5 KIF11	2.68e-05	721	72	10	M10237
Coexpression	DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.00e-05	323	72	7	M2156
Coexpression	BIDUS_METASTASIS_UP	WDHD1 DSP PAK2 MCM10 RRM1 KIF11	3.30e-05	221	72	6	M15866
Coexpression	KAUFFMANN_DNA_REPAIR_GENES	PARP4 BRCA2 POLA1 REV3L RRM1 POLQ	4.12e-05	230	72	6	M11563
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KDM3A WDHD1 BRCA2 MYO9B LTN1 NAV3 REV3L KAT6B ACBD3 KIF11	1.12e-04	856	72	10	M4500
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	1.18e-04	402	72	7	MM454
Coexpression	VILLANUEVA_LIVER_CANCER_KRT19_UP	IFT57 POLA1 GNPTAB MCM10 RRM1	1.22e-04	175	72	5	M336
Coexpression	GSE14415_INDUCED_VS_NATURAL_TREG_DN	WDHD1 POLA1 TEX9 RRM1 KIF11	1.43e-04	181	72	5	M2969
Coexpression	WANG_CLIM2_TARGETS_DN	ELOA CEBPZ PEX1 ACBD3 DUS1L	1.47e-04	182	72	5	M8577
Coexpression	BURTON_ADIPOGENESIS_3	POLA1 MCM10 RRM1 KIF11	1.75e-04	101	72	4	M1577
Coexpression	GSE45365_WT_VS_IFNAR_KO_BCELL_DN	WDHD1 ENPP3 HS2ST1 POLQ KIF11	1.88e-04	192	72	5	M9987
Coexpression	BURTON_ADIPOGENESIS_3	POLA1 MCM10 RRM1 KIF11	1.96e-04	104	72	4	MM1180
Coexpression	STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN	WDHD1 MCM10 RRM1	1.97e-04	41	72	3	M19002
Coexpression	TABULA_MURIS_SENIS_MARROW_CD4_POSITIVE_ALPHA_BETA_T_CELL_AGEING	ANP32A TMSB10 ANP32D	2.11e-04	42	72	3	MM3791
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN	REXO4 LMLN FUNDC2 TEX9 ETFRF1	2.12e-04	197	72	5	M6525
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN	AP2A2 FUNDC2 TEX9 ETFRF1 DUS1L	2.17e-04	198	72	5	M6516
Coexpression	GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN	AP2A2 HS2ST1 TLR5 DIAPH2 PAK2	2.17e-04	198	72	5	M7228
Coexpression	GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN	KMT2C VWA8 ENPP3 TLR5 RALGAPA2	2.17e-04	198	72	5	M8624
Coexpression	GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_DN	PTPRB CEBPZ MYO9B PHTF1 IWS1	2.22e-04	199	72	5	M8770
Coexpression	GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP	POLA1 MCM10 RRM1 POLQ KIF11	2.27e-04	200	72	5	M3577
Coexpression	GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP	PARP4 POLA1 HS2ST1 DIAPH2 RRM1	2.27e-04	200	72	5	M9922
Coexpression	GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN	ELOA AP2A2 DSP ANP32A NUDC	2.27e-04	200	72	5	M4352
Coexpression	GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN	WDHD1 RPRD2 REV3L ULK2 GOLGB1	2.27e-04	200	72	5	M7418
Coexpression	TABULA_MURIS_SENIS_LIVER_MATURE_NK_T_CELL_AGEING	PAK2 TMSB10 KAT6B NUDC	3.17e-04	118	72	4	MM3754
Coexpression	BENPORATH_NANOG_TARGETS	KDM3A WDHD1 CEBPZ GNPTAB ANP32A LARS1 PEX1 TMSB10 NKTR IWS1	3.56e-04	988	72	10	M6616
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	SMAP1 BRCA2 CEBPZ POLA1 SLMAP REV3L TEX9 POLQ IWS1	8.21e-07	311	70	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	B cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Fetal Liver, avg-1	RAG1 WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 POLQ KIF11 PTK7	1.09e-06	418	70	10	GSM538350_500
CoexpressionAtlas	B cells, proB.FrA.BM, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Bone marrow, avg-2	RAG1 WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 POLQ KIF11	5.03e-06	388	70	9	GSM538352_500
CoexpressionAtlas	Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2	RAG1 WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11 PTK7	7.85e-06	410	70	9	GSM791122_500
CoexpressionAtlas	B cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Fetal Liver, avg-2	RAG1 WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 POLQ KIF11	9.34e-06	419	70	9	GSM538348_500
CoexpressionAtlas	B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Fetal Liver, avg-1	RAG1 WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 POLQ KIF11	9.89e-06	422	70	9	GSM538357_500
CoexpressionAtlas	B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2	RAG1 WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 POLQ KIF11	9.89e-06	422	70	9	GSM538355_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	CEBPZ POLA1 ANP32A TEX9 POLQ KAT6B IWS1 PAPOLG	1.22e-05	328	70	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	SMAP1 BRCA2 SLC17A1 CEBPZ POLA1 LMLN SLMAP REV3L MCM10 TEX9 POLQ PHTF1 IWS1	1.80e-05	989	70	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	SMAP1 FAP BRCA2 POLA1 RSF1 ANP32A SLMAP DIAPH2 REV3L MCM10 RRM1 KIF11 IWS1 PAPOLG	5.14e-05	1257	70	14	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	VWA8 IFT57 CEBPZ POLA1 ANP32A TEX9 POLQ KAT6B IWS1 PAPOLG	5.38e-05	654	70	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	BRCA2 CEBPZ RSF1 TEX9 POLQ IWS1	5.74e-05	204	70	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3	RAG1 WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	5.89e-05	409	70	8	GSM399452_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	BRCA2 CEBPZ POLA1 RSF1 ANP32A TEX9 POLQ KIF11 IWS1	6.08e-05	532	70	9	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	alpha beta T cells, T.ISP.Th, 4- 8+ TCR-/lo 24hi, Thymus, avg-3	RAG1 WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	6.74e-05	417	70	8	GSM399403_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3	WDHD1 MYO1E DSP POLA1 MCM10 RRM1 POLQ KIF11	6.97e-05	419	70	8	GSM476664_500
CoexpressionAtlas	alpha beta T cells, preT.DN2B.Th, Lin-/lo CD25hi CD44+ cKitint, Thymus, avg-2	RAG1 WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	7.08e-05	420	70	8	GSM791141_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	ELOA BRCA2 CEBPZ POLA1 GNPTAB LMLN NKTR TEX9 POLQ IWS1 PAPOLG	8.10e-05	831	70	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	alpha beta T cells, T.DN4.Th, Lin-/lo CD25- CD44- CD28+, Thymus, avg-3	RAG1 MCM10 RRM1 KIF11	1.79e-04	85	70	4	GSM791154_100
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	WDHD1 BRCA2 DSP POLA1 ENPP3 LARS1 MCM10 TEX9 NUDC KIF11	2.30e-04	781	70	10	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	SMAP1 FAP BRCA2 POLA1 RSF1 ANP32A SLMAP DIAPH2 REV3L MCM10 RRM1 KIF11 IWS1 PAPOLG	2.49e-04	1459	70	14	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	alpha beta T cells, preT.DN3-4.Th, Lin-/lo CD25int CD44- CD28+, Thymus, avg-3	RAG1 WDHD1 BRCA2 POLA1 MCM10 RRM1 KIF11	3.30e-04	397	70	7	GSM791143_500
CoexpressionAtlas	alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3	RAG1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.35e-04	398	70	7	GSM399397_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000	SMAP1 FAP BRCA2 SLC17A1 SLFN5 REV3L TEX9 ETFRF1 ULK2 GOLGB1 IWS1	3.38e-04	979	70	11	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000
CoexpressionAtlas	B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Bone marrow, avg-2	RAG1 WDHD1 BRCA2 IFT57 POLA1 RRM1 KIF11	3.40e-04	399	70	7	GSM538345_500
CoexpressionAtlas	B cells, proB.FrBC.FL, CD19+ IgM- CD43+ CD24+ AA4.1+ CD45R+, Fetal Liver, avg-3	RAG1 WDHD1 POLA1 MCM10 RRM1 POLQ KIF11	3.45e-04	400	70	7	GSM538358_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	BRCA2 IFT57 CEBPZ POLA1 ANP32A TEX9 POLQ KAT6B CTSK IWS1 PAPOLG	3.50e-04	983	70	11	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	Stem Cells, SC.MEP.BM, Lineage- Kit+ Sca1- CD34- FcgR-/low, Bone marrow, avg-2	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.50e-04	401	70	7	GSM791108_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	4.00e-04	410	70	7	GSM538387_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	BRCA2 POLA1 TEX9 POLQ IWS1	4.31e-04	192	70	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	alpha beta T cells, preT.DN2.Th, Lin-/lo CD25hi CD44+ cKit+, Thymus, avg-3	RAG1 WDHD1 IFT57 POLA1 MCM10 RRM1 KIF11	4.62e-04	420	70	7	GSM791136_500
CoexpressionAtlas	B cells, MLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R-, Bone marrow, avg-2	WDHD1 BRCA2 IFT57 POLA1 MCM10 RRM1 KIF11	4.75e-04	422	70	7	GSM791124_500
CoexpressionAtlas	Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	4.82e-04	423	70	7	GSM791126_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	SMAP1 BRCA2 POLA1 ANP32A SLMAP DIAPH2 MCM10 ULK2 KIF11 PHTF1 PAPOLG	6.58e-04	1060	70	11	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	WDHD1 POLA1 LTN1 KIF11	7.32e-04	123	70	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	B cells, proB.CLP.BM, AA4.1+ CD117+ IL7R+ CD45R- CD24- CD19- IgM-, Bone marrow, avg-1	RAG1 BRCA2 IFT57 POLA1 RRM1 KIF11	8.67e-04	338	70	6	GSM538347_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	BRCA2 CEBPZ POLA1 RSF1 ANP32A TEX9 IWS1	8.86e-04	469	70	7	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_top-relative-expression-ranked_1000	SMAP1 PTPRB DSP ANP32A SLMAP DIAPH2 RPRD2 TMSB10 PPL	9.64e-04	774	70	9	gudmap_developingLowerUrinaryTract_P1_bladder_1000_B
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	BRCA2 POLA1 ANP32A TEX9 IWS1	1.01e-03	232	70	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	SMAP1 ELOA BRCA2 GNPTAB NKTR REV3L ACBD3 IWS1 PAPOLG	1.02e-03	780	70	9	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	BRCA2 SUPT6H ANP32A SLMAP TEX9 ACBD3 GOLGB1 IWS1	1.06e-03	629	70	8	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	WDHD1 BRCA2 CEBPZ POLA1 ENPP3 LARS1 MCM10 NUDC KIF11	1.16e-03	795	70	9	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000	WDHD1 BRCA2 DSP POLA1 ENPP3 LARS1 MCM10 NUDC KIF11	1.20e-03	799	70	9	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlas	kidney_e13.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	PTPRB LTN1 SLFN5	1.24e-03	64	70	3	gudmap_kidney_e13.5_Podocyte_MafB_k1_1000
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	1.66e-08	179	72	7	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	1.66e-08	179	72	7	80112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PTPRB WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	2.50e-08	190	72	7	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	COVID-19_Severe-T/NK_proliferative\|World / disease group, cell group and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.32e-08	198	72	7	48045689d0969ff0a14eee7086b8e19b0d6b6065
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	e98ff036d04fc78dffef156bdc0d644532274067
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	7feedb0bf84a3361c8ab5b6674ff64e8ff140c23
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	123fbf2122aa221d8cbf3aef9361ba0982c07695
ToppCell	COVID-19_Severe-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Severe / Disease group, lineage and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	ddae7fe7633661f15d3c79f5187415ffbfecce67
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.44e-08	199	72	7	6b1304417cf9c44ca70d2bfc2b5acc1a206f25b6
ToppCell	severe-T/NK_proliferative\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	9d6e7e2d6cfa8c96bbb5c187815df96ecaa5475c
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Severe / Disease, condition lineage and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	0892603e604c2a945dd720685d45970f855bd5d3
ToppCell	mild-T/NK_proliferative\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	25b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCell	severe-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	d341f4e500377a5bef82c24bf64704b981053336
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	04bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_non-vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	f6b5320cdfe640a71e6e2df26f30d42e64b1c921
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	3.56e-08	200	72	7	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ	3.05e-07	167	72	6	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 POLA1 MCM10 POLQ KIF11	3.27e-07	169	72	6	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 POLA1 MCM10 POLQ KIF11	3.27e-07	169	72	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP BRCA2 RXFP2 MCM10 POLQ KIF11	3.50e-07	171	72	6	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAP BRCA2 RXFP2 MCM10 POLQ KIF11	3.50e-07	171	72	6	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 POLA1 MCM10 RRM1 POLQ KIF11	4.73e-07	180	72	6	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	5.05e-07	182	72	6	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	5.22e-07	183	72	6	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POLA1 MCM10 RRM1 POLQ CTSK KIF11	5.38e-07	184	72	6	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDHD1 POLA1 MCM10 RRM1 POLQ KIF11	6.11e-07	188	72	6	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDHD1 POLA1 MCM10 RRM1 POLQ KIF11	6.70e-07	191	72	6	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDHD1 POLA1 MCM10 RRM1 POLQ KIF11	6.70e-07	191	72	6	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	Control-Lymphoid_T/NK-T/NK_proliferative\|Control / Disease group, lineage and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	9bbb124001fba7450f4639f47f9b720a483e7242
ToppCell	Control-Lymphocyte-T_NK-T_NK_proliferative\|Control / Disease, Lineage and Cell Type	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	17744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.34e-07	194	72	6	e14f66f7584909621b776292fbd52808273fd2ee
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ	7.56e-07	195	72	6	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDHD1 POLA1 MCM10 RRM1 CTSK KIF11	7.56e-07	195	72	6	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ	7.56e-07	195	72	6	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.56e-07	195	72	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Healthy/Control-T/NK_proliferative\|Healthy/Control / Disease group and Cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.56e-07	195	72	6	957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ	7.56e-07	195	72	6	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 POLA1 MCM10 RRM1 POLQ	7.79e-07	196	72	6	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.79e-07	196	72	6	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	Healthy-T/NK_proliferative\|Healthy / disease group, cell group and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.79e-07	196	72	6	91e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCell	Control-T/NK_proliferative\|Control / Disease condition and Cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	7.79e-07	196	72	6	7b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCell	severe_COVID-19-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	4b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCell	Healthy-T/NK_proliferative\|World / disease group, cell group and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCell	Healthy/Control-T/NK_proliferative\|World / Disease group and Cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	4a4d3083938783d6f5b87da02f10e501917da0b4
ToppCell	COVID-19_Severe-T/NK_proliferative\|COVID-19_Severe / Disease condition and Cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	21861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCell	Healthy_donor-T/NK_proliferative\|Healthy_donor / disease group, cell group and cell class (v2)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.02e-07	197	72	6	b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCell	COVID-19_Moderate-T/NK_proliferative\|COVID-19_Moderate / disease group, cell group and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.26e-07	198	72	6	166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCell	severe_COVID-19-T/NK_proliferative\|severe_COVID-19 / disease group, cell group and cell class (v2)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.26e-07	198	72	6	ed86b0247006befe55400c287d334d2202b470bd
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.26e-07	198	72	6	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	(0)_NK_Dividing\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.26e-07	198	72	6	5ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	11c3d9fe811a4619347f47d2b0e94066e3085625
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	FHAD1 LMLN RSF1 SLFN5 TEX9 GOLGB1	8.51e-07	199	72	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Leuk-UTI-Lymphocyte-T_NK-T_NK_proliferative\|Leuk-UTI / Disease, Lineage and Cell Type	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	87113d398585076ece86b9098781e817f8ca241b
ToppCell	VE-cycling\|VE / Condition, Cell_class and T cell subcluster	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	47c47ebc318a0b98841ca2656837bbd068899559
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	36c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCell	COVID-19-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	2e9ee10a069afca5dbd9f0863cf90a66db1a6ffb
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCell	COVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Mild / Disease group, lineage and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	FHAD1 RSF1 SLFN5 REV3L GOLGB1 IWS1	8.51e-07	199	72	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	7beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCell	Healthy_donor-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	1311dfd74b991f48b047a439f04f9bf7dfaa0e7a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	WDHD1 BRCA2 POLA1 MCM10 POLQ KIF11	8.51e-07	199	72	6	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	VE-cycling-\|VE / Condition, Cell_class and T cell subcluster	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCell	Transverse-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	WDHD1 MYO1E MCM10 RRM1 POLQ KIF11	8.51e-07	199	72	6	170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 MYO1E POLA1 MCM10 RRM1 KIF11	8.76e-07	200	72	6	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Mild / Disease, condition lineage and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	6126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCell	Control-Control-Lymphocyte-T/NK-T/NK_proliferative\|Control / Disease, condition lineage and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	6cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCell	control-T/NK_proliferative\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	1da366e35a05f73253629663eeea1fed4ebd7b52
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 MYO1E POLA1 MCM10 RRM1 KIF11	8.76e-07	200	72	6	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	healthy_donor-Lymphocytic-Proliferative_Lymphocyte-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell	356C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	5d11a2c0021805e78d97dc1638bf73ca1faede66
ToppCell	BL-critical-LOC-Lymphoid-Treg\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	04d95a9102248e98eed069840ea6d3d23a243fd5
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-T/NK_proliferative\|Leuk-UTI / Disease, condition lineage and cell class	WDHD1 BRCA2 MCM10 RRM1 POLQ KIF11	8.76e-07	200	72	6	093e97395be23092229521cc55aaaee8befbc149
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7\|TCGA-Brain / Sample_Type by Project: Shred V9	WDHD1 BRCA2 MCM10 POLQ KIF11	2.79e-06	136	72	5	d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 MCM10 RRM1 POLQ KIF11	5.45e-06	156	72	5	955547dfeb1b1ad4957b4338701055726b22619f
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	WDHD1 BRCA2 MCM10 RRM1 KIF11	8.04e-06	169	72	5	a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 POLA1 MCM10 POLQ KIF11	8.04e-06	169	72	5	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	WDHD1 BRCA2 MCM10 RRM1 KIF11	8.04e-06	169	72	5	195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WDHD1 POLA1 MCM10 RRM1 KIF11	8.76e-06	172	72	5	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	WDHD1 BRCA2 MCM10 POLQ KIF11	9.53e-06	175	72	5	f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T\|Lung / Manually curated celltypes from each tissue	POLA1 MCM10 RRM1 POLQ KIF11	9.79e-06	176	72	5	a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BRCA2 MCM10 RRM1 POLQ KIF11	1.06e-05	179	72	5	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM10 RRM1 POLQ CTSK KIF11	1.15e-05	182	72	5	21dcab170ffeef89faa9fee5008568cb6e15c694
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; PC3; HT_HG-U133A	WDHD1 BRCA2 SUPT6H KAT6B ACBD3 PPL PAPOLG	2.63e-06	196	71	7	1794_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; HL60; HG-U133A	KDM3A WDHD1 RSF1 RPRD2 MCM10 KAT6B PAPOLG	2.91e-06	199	71	7	1763_DN
Drug	BuPdGTP	POLA1 ENPP3 REV3L POLQ	3.75e-06	34	71	4	CID000123713
Drug	pyrophosphate	MYO1E IFT57 MYO9B POLA1 ENPP3 LARS1 PLCD1 REV3L POLQ ALPI PAPOLG	5.41e-06	654	71	11	CID000001023
Drug	AC1L2J0W	POLA1 REV3L RRM1 POLQ	8.88e-06	42	71	4	CID000072957
Drug	iron center	RAG1 ENPP3 LARS1 RRM1 ALPI	9.14e-06	90	71	5	CID000029154
Drug	Clofarabine	POLA1 RRM1	9.59e-06	2	71	2	DB00631
Drug	captan	POLA1 REV3L RRM1 POLQ	1.40e-05	47	71	4	CID000008606
Drug	PG E	POLA1 TMSB10 PPL	1.92e-05	17	71	3	CID000031217
Drug	2'-deoxyadenosine 5'-triphosphate	POLA1 REV3L RRM1 POLQ PAPOLG	2.32e-05	109	71	5	CID000000622
Drug	CPG-oligonucleotide	PARP4 BRCA2 POLA1 TLR5 REV3L POLQ	2.38e-05	184	71	6	ctd:C408982
Drug	poly(vA	POLA1 REV3L POLQ	2.72e-05	19	71	3	CID000429118
Drug	dercitin	POLA1 REV3L POLQ	2.72e-05	19	71	3	CID000130774
Drug	aucubigenin	POLA1 REV3L POLQ	2.72e-05	19	71	3	CID000163040
Drug	5-ClAU	POLA1 REV3L POLQ	2.72e-05	19	71	3	CID000126441
Drug	Fludarabine	POLA1 RRM1	2.87e-05	3	71	2	DB01073
Drug	N-ethylmaleimide	MYO1E MYO9B POLA1 REV3L POLQ GOLGB1 KIF11 ALPI PAPOLG	2.92e-05	511	71	9	CID000004362
Drug	OXT-ATP	POLA1 REV3L POLQ	3.19e-05	20	71	3	CID000454146
Drug	AC1MHT6K	POLA1 REV3L POLQ	3.19e-05	20	71	3	CID003010960
Drug	5-aminosalicylic acid; Down 200; 100uM; MCF7; HG-U133A	SUPT6H HS2ST1 GNPTAB PAK2 KIF11 PHTF1	3.59e-05	198	71	6	124_DN
Drug	AC1L3V16	POLA1 REV3L POLQ	3.71e-05	21	71	3	CID000122664
Drug	parazoanthoxanthin A	POLA1 REV3L POLQ	3.71e-05	21	71	3	CID000323259
Drug	3'-deoxythymidine	POLA1 REV3L RRM1 POLQ	3.96e-05	61	71	4	CID000005280
Drug	petasiphenol	POLA1 REV3L POLQ	4.29e-05	22	71	3	CID006438779
Drug	BVdUTP	POLA1 REV3L POLQ	4.29e-05	22	71	3	CID006438404
Drug	U-78036	POLA1 REV3L POLQ	4.29e-05	22	71	3	CID000072244
Drug	AC1LA211	POLA1 REV3L POLQ	4.29e-05	22	71	3	CID000480107
Drug	BrVarafUTP	POLA1 REV3L POLQ	5.61e-05	24	71	3	CID005273539
Drug	Cladribine	POLA1 RRM1	5.73e-05	4	71	2	DB00242
Drug	AC1L1CVV	POLA1 REV3L POLQ	7.18e-05	26	71	3	CID000027281
Drug	AC1Q6S3R	POLA1 REV3L RRM1 POLQ	7.20e-05	71	71	4	CID000000625
Drug	araTTP	POLA1 REV3L POLQ	8.06e-05	27	71	3	CID000072188
Drug	R)-PCV-TP	POLA1 REV3L POLQ	9.00e-05	28	71	3	CID000506602
Drug	AC1L1GVK	POLA1 REV3L RRM1 POLQ	9.40e-05	76	71	4	CID000003860
Drug	AC1LAIP3	POLA1 REV3L POLQ	1.00e-04	29	71	3	CID000469173
Drug	UC-3	POLA1 REV3L POLQ	1.00e-04	29	71	3	CID003000477
Drug	butylphenyl	POLA1 REV3L POLQ	1.23e-04	31	71	3	CID000143181
Drug	acyclovir triphosphate	POLA1 REV3L POLQ	1.35e-04	32	71	3	CID000084000
Drug	NSC343256	POLA1 ENPP3	1.43e-04	6	71	2	CID000335091
Drug	2'-chloro-2'-deoxyadenosine	POLA1 RRM1	1.43e-04	6	71	2	CID000100327
Drug	AC1L6XCD	POLA1 ENPP3	1.43e-04	6	71	2	CID000325952
Drug	AC1Q6S3Y	POLA1 REV3L RRM1 POLQ	1.81e-04	90	71	4	CID000000646
Drug	S)-HPMPA	POLA1 RRM1 POLQ	1.93e-04	36	71	3	CID000072253
Drug	9-ODA	POLA1 PPL	1.99e-04	7	71	2	CID000068167
Disease	candidiasis (implicated_via_orthology)	SMAP1 ELOA ANP32A ANP32D	3.27e-06	44	68	4	DOID:1508 (implicated_via_orthology)
Disease	cathepsin O measurement	GNPTAB CTSK	1.57e-05	3	68	2	EFO_0802375
Disease	ductal carcinoma in situ (is_implicated_in)	BRCA2 PAK2	1.09e-04	7	68	2	DOID:0060074 (is_implicated_in)
Disease	cathepsin S measurement	GNPTAB CTSK	1.45e-04	8	68	2	EFO_0008073
Disease	Prostatic Neoplasms	RAG1 KMT2C BRCA2 TLR5 IRAK4 RPRD2 PPL	5.38e-04	616	68	7	C0033578
Disease	Malignant neoplasm of prostate	RAG1 KMT2C BRCA2 TLR5 IRAK4 RPRD2 PPL	5.38e-04	616	68	7	C0376358
Disease	Neural Tube Defects	RRM1 PTK7	2.18e-03	30	68	2	C0027794

Protein segments in the cluster

Peptide	Gene	Start	Entry
QLKKKTGKLLNLSPQ	CTSK	151	P43235
EVLSKNKQKKQLRNP	DUS1L	366	Q6P1R4
SIANLPKLNKLKKLE	ANP32A	56	P39687
EETKNKPKLNIQIKT	DIAPH2	36	O60879
ILNKAQEPPKSKKVQ	AP2A2	286	O94973
LKRKSLQPNLQLSKK	RAG1	221	P15918
QLNNQKKPALKKLTL	IWS1	576	Q96ST2
AIQKIKKQKQRPSEE	KAT6B	16	Q8WYB5
NLNVQAKAKPLKKAT	KIAA1107	186	Q9UPP5
SNLLQVLQKPKSSLK	LTN1	516	O94822
IKNKNNFIQTKSIPK	PTPRB	766	P23467
KPKLKLKIINQNSVA	KMT2C	1201	Q8NEZ4
NQLKTKLPENLSSKV	GNPTAB	241	Q3T906
NKPEVNQKLTKKALI	KIF11	361	P52732
KKNLVKNKLFPQAIS	LMLN	111	Q96KR4
KKQPNSILKEIKNSL	LMOD2	486	Q6P5Q4
QLKKEIQALKDTKPQ	PPL	1271	O60437
LSNKKSLLQPKEKEE	NAV3	456	Q8IVL0
KAKKNANKPLLDEIV	ACBD3	466	Q9H3P7
QVLTKTNPNSIKKKQ	MCM10	671	Q7L590
LKNIFLKNKDVKNPE	ETFRF1	36	Q6IPR1
KYLPQQQKKKLQTDI	PARP4	16	Q9UKK3
TNLPLDKLSEQKEKK	RALGAPA2	661	Q2PPJ7
INLKLTTQPKKQKHL	GREB1L	201	Q9C091
RNVKKLAVTKPNNIK	POLA1	121	P09884
LPKVNKNKNSIVDPK	PLCD1	641	P51178
AAKKLQPIQKVAKNL	ALPI	41	P09923
LPAEILQKKKKQSLS	PAPOLG	496	Q9BWT3
AIKQINLQKQPKKEL	PAK2	276	Q13177
LQLNTEKEQKPRKKT	FHAD1	1091	B1AJZ9
APLVKIKQSLTKLKQ	IFT57	371	Q9NWB7
KSVLTDPAKLKKLQQ	KDM3A	511	Q9Y4C1
LALDNQKKLSKPQSI	BRCA2	1051	P51587
GKNLDSVQKLPKVNK	ELOA	471	Q14241
TLATEQPVKKNTLKK	ENPP3	6	O14638
KEKDNKTSFPLQIKQ	POLQ	1106	O75417
QNLVNKSKKIVQLKP	DSP	436	P15924
KNKRPDIKKVQQLLQ	IRAK4	441	Q9NWZ3
TEKLKNDQQAKIPLK	RSF1	371	Q96T23
NDQQAKIPLKKREIK	RSF1	376	Q96T23
NLKKKLDQLKSTLPD	RPRD2	301	Q5VT52
VKLLSPKQQQSKTKQ	PEX1	336	O43933
ENSSKKEVKIPKINN	CEBPZ	111	Q03701
KAKEQLKIRKSNQIP	FUNDC2	141	Q9BWH2
KIIQQNKKETSPQVK	REXO4	101	Q9GZR2
KSQINLIDKKWKPLQ	NKTR	1216	P30414
PKTQIAKEKLDQLKQ	LARS1	646	Q9P2J5
LPNTSTKKLLDNIKN	SLC17A1	56	Q14916
TEKKLPTKQTIAKLQ	HS2ST1	291	Q7LGA3
KDLKLLQKLNLSSNP	RXFP2	326	Q8WXD0
LPTSDEQKKQEILKK	NUDC	301	Q9Y266
SIANLPKLNKLKKLE	ANP32D	56	O95626
QLKRQKKTKAPQDVE	C11orf98	101	E9PRG8
ILILGNPKLKQNAKK	TAS2R1	276	Q9NYW7
NALKNIQLPKEEIKK	FAP	496	Q12884
QDIETLKKFLLNKKP	SUPT6H	831	Q7KZ85
QKEKIPKLLKVDSLN	REV3L	1591	O60673
KSIEQTQIKGLKNKP	PHTF1	26	Q9UMS5
KKPNKKEQLTLVNNV	PHTF1	691	Q9UMS5
NPIQFTLNKEKLKDK	RRM1	746	P23921
KENLNLSKKQKPLDF	WDHD1	1101	O75717
KNNLKLLREKGNNKP	SLMAP	786	Q14BN4
KPLTAEKLQKKDQQL	SMAP1	186	Q8IYB5
PKEKLAQSQKKVAQL	TTC23L	66	Q6PF05
AKLKKTETQEKNTLP	TMSB10	16	P63313
INKKNLSKSQILLGK	ULK2	41	Q8IYT8
KEKKKDNNIPLQTVA	TLR5	841	O60602
NKIPKDNKQRLEILK	VWA8	1776	A3KMH1
KLKSQPLSTKQKVAL	PTK7	896	Q13308
KTKNIDPVNKVQNKL	TEX9	106	Q8N6V9
ENQPLKKLVSFSKKN	SLFN5	611	Q08AF3
NLPKKSVIKNEKVNG	ZNF181	191	Q2M3W8
QPKLDELQKLISKKE	GOLGB1	1391	Q14789
QKQLPLKFSNTLELK	MYO1E	866	Q12965
KQIIPKNLLDSKSLK	MYO9B	786	Q13459