Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF140 ARNT ZNF35 FEZF1 ZNF460 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529 NR1H4	1.77e-04	1412	74	15	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF140 ARNT ZNF35 FEZF1 ZNF460 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529 NR1H4	2.53e-04	1459	74	15	GO:0000977
Domain	ZINC_FINGER_C2H2_2	ZNF140 ZNF35 FEZF1 ZNF460 HELZ2 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	2.07e-07	775	72	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF140 ZNF35 FEZF1 ZNF460 HELZ2 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	2.14e-07	777	72	15	PS00028
Domain	Znf_C2H2-like	ZNF140 ZNF35 FEZF1 ZNF460 HELZ2 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	2.91e-07	796	72	15	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	ZNF140 ZNF35 FEZF1 ZNF460 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	3.41e-07	694	72	14	IPR013087
Domain	ZnF_C2H2	ZNF140 ZNF35 FEZF1 ZNF460 HELZ2 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	3.53e-07	808	72	15	SM00355
Domain	-	ZNF140 ZNF35 FEZF1 ZNF460 AEBP2 ZNF324 ZNF621 ZNF350 ZNF619 ZFP69B BCL6 SNAI3 ZNF529	1.70e-06	679	72	13	3.30.160.60
Domain	Znf_C2H2	ZNF140 ZNF35 FEZF1 ZNF460 AEBP2 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	1.99e-06	805	72	14	IPR007087
Domain	zf-C2H2	ZNF140 ZNF35 FEZF1 ZNF460 ZNF324 ZNF621 ZNF350 ZNF619 ZFP69B BCL6 SNAI3 ZNF529	1.23e-05	693	72	12	PF00096
Domain	TOM1	TOM1L2 TOM1	4.39e-05	3	72	2	IPR014645
Domain	-	TOM1L2 TOM1	2.18e-04	6	72	2	1.20.58.160
Domain	GAT	TOM1L2 TOM1	2.18e-04	6	72	2	PS50909
Domain	GAT_dom	TOM1L2 TOM1	2.18e-04	6	72	2	IPR004152
Domain	GAT	TOM1L2 TOM1	2.18e-04	6	72	2	PF03127
Domain	DUF3585	MICALL1 MICAL1	3.04e-04	7	72	2	IPR022735
Domain	DUF3585	MICALL1 MICAL1	3.04e-04	7	72	2	PF12130
Domain	KRAB	ZNF140 ZNF460 ZNF324 ZNF621 ZNF350 ZFP69B ZNF529	4.53e-04	358	72	7	PS50805
Domain	KRAB	ZNF140 ZNF460 ZNF324 ZNF621 ZNF350 ZFP69B ZNF529	4.53e-04	358	72	7	PF01352
Domain	VHS	TOM1L2 TOM1	5.18e-04	9	72	2	PF00790
Domain	VHS	TOM1L2 TOM1	5.18e-04	9	72	2	PS50179
Domain	VHS	TOM1L2 TOM1	5.18e-04	9	72	2	SM00288
Domain	VHS_dom	TOM1L2 TOM1	5.18e-04	9	72	2	IPR002014
Domain	KRAB	ZNF140 ZNF460 ZNF324 ZNF621 ZNF350 ZFP69B ZNF529	5.43e-04	369	72	7	SM00349
Domain	KRAB	ZNF140 ZNF460 ZNF324 ZNF621 ZNF350 ZFP69B ZNF529	5.52e-04	370	72	7	IPR001909
Domain	zf-C2H2_6	ZNF140 FEZF1 ZNF324 ZNF621 ZNF619 ZFP69B	1.33e-03	314	72	6	PF13912
Domain	G-protein_beta_WD-40_rep	DAW1 WDR86 TAF5	4.33e-03	85	72	3	IPR020472
Domain	-	TOM1L2 TOM1	4.49e-03	26	72	2	1.25.40.90
Domain	Cys-rich_flank_reg_C	NTRK2 ADGRA2 ADGRA3	5.08e-03	90	72	3	IPR000483
Domain	LRRCT	NTRK2 ADGRA2 ADGRA3	5.08e-03	90	72	3	SM00082
Domain	HRM	ADGRA2 ADGRA3	5.19e-03	28	72	2	PF02793
Domain	ENTH_VHS	TOM1L2 TOM1	5.56e-03	29	72	2	IPR008942
Domain	GPS	ADGRA2 ADGRA3	7.59e-03	34	72	2	SM00303
Domain	GPS	ADGRA2 ADGRA3	8.03e-03	35	72	2	PF01825
Domain	GPS	ADGRA2 ADGRA3	8.48e-03	36	72	2	PS50221
Domain	GPS	ADGRA2 ADGRA3	8.95e-03	37	72	2	IPR000203
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	NAT1 ARNT LMOD1 ZNF350 BCL6 XRCC5 NR1H4 CDK4	3.24e-06	421	74	8	19692168
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MICALL1 PIKFYVE ABCA2 ARHGEF40 CLTCL1 SZT2 INTS1 HELZ2 CLASP2 SRGAP2 ADGRA2 BAHD1	3.56e-06	1105	74	12	35748872
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	PIKFYVE HELZ2 BCL6 DDX6	9.59e-06	62	74	4	16147992
Pubmed	BCL6--regulated by AhR/ARNT and wild-type MEF2B--drives expression of germinal center markers MYBL1 and LMO2.	ARNT BCL6	1.34e-05	3	74	2	25769544
Pubmed	Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome.	TOM1L2 TOM1	1.34e-05	3	74	2	23023224
Pubmed	Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.	ADGRA2 ADGRA3	1.34e-05	3	74	2	15021905
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	ARNT LMOD1 ZNF350 BCL6 XRCC5 NR1H4 CDK4	1.52e-05	374	74	7	19625176
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MICALL1 IFT140 ABCA2 SZT2 ANKRD50 ADGRA2 BAHD1 STAB1	1.70e-05	529	74	8	14621295
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	ARNT LMOD1 ZNF350 BCL6 XRCC5 NR1H4 CDK4	1.72e-05	381	74	7	18676680
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	ARNT LMOD1 ZNF350 BCL6 XRCC5 NR1H4 CDK4	1.75e-05	382	74	7	19170196
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ASNSD1 PTCHD1 ARNT UBR5 SZT2 RECQL5 INTS1 AEBP2 CLASP2 BAHD1 DDX6 CDK4	2.23e-05	1327	74	12	32694731
Pubmed	Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.	TFB2M PNP	2.67e-05	4	74	2	12068295
Pubmed	Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles.	TOM1L2 TOM1	2.67e-05	4	74	2	32311122
Pubmed	MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.	MICALL1 MICAL1	4.45e-05	5	74	2	12110185
Pubmed	Recruitment of clathrin onto endosomes by the Tom1-Tollip complex.	TOM1L2 TOM1	4.45e-05	5	74	2	16412388
Pubmed	The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.	MICALL1 MICAL1	4.45e-05	5	74	2	18094055
Pubmed	Ku proteins function as corepressors to regulate farnesoid X receptor-mediated gene expression.	XRCC5 NR1H4	4.45e-05	5	74	2	19833092
Pubmed	MICAL-1 isoforms, novel rab1 interacting proteins.	MICALL1 MICAL1	4.45e-05	5	74	2	12788069
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	NTRK2 ADGRA2 ADGRA3	5.28e-05	34	74	3	18848646
Pubmed	A peptide aptamer to antagonize BCL-6 function.	BCL6 CDK4	6.66e-05	6	74	2	16331266
Pubmed	There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.	ADGRA2 ADGRA3	9.31e-05	7	74	2	12565841
Pubmed	The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia.	TOM1L2 TOM1	9.31e-05	7	74	2	37019113
Pubmed	HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia.	ARNT XRCC5	1.24e-04	8	74	2	35031618
Pubmed	MRE11 complex links RECQ5 helicase to sites of DNA damage.	UBR5 RECQL5	2.43e-04	11	74	2	19270065
Pubmed	Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart.	ACAN STAB1	2.91e-04	12	74	2	18296617
Pubmed	EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.	MICALL1 MICAL1	3.43e-04	13	74	2	26833786
Pubmed	Glycogen synthase kinase 3 β-dependent Snail degradation directs hepatocyte proliferation in normal liver regeneration.	NR1H4 CDK4	5.26e-04	16	74	2	21690373
Pubmed	Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.	DDX6 CDK4	5.95e-04	17	74	2	21383967
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF140 ZNF460 ZNF324 ZNF529	6.15e-04	181	74	4	37372979
Pubmed	Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking.	ARNT UBR5	6.68e-04	18	74	2	26598607
Pubmed	Defining the membrane proteome of NK cells.	ABCA2 CLTCL1 UBR5 INTS1 HELZ2 CLASP2 NUF2 XRCC5 DDX6	8.22e-04	1168	74	9	19946888
Pubmed	Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.	ARNT ACAN	8.28e-04	20	74	2	20495570
Pubmed	Identification of substrates of SMURF1 ubiquitin ligase activity utilizing protein microarrays.	TOM1L2 TOM1 ANKRD50	8.62e-04	87	74	3	20804422
Pubmed	HES1 is a novel downstream modifier of the SHH-GLI3 Axis in the development of preaxial polydactyly.	ACAN CDK4	9.14e-04	21	74	2	34928956
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	ARNT ACCS BCL6 XRCC5 CDK4	9.27e-04	351	74	5	20453000
Pubmed	Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays.	TOM1L2 ACAN NTRK2 TOM1	9.42e-04	203	74	4	19953087
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CLTCL1 SZT2 NTRK2 HELZ2 DDX6 STAB1	1.16e-03	552	74	6	10737800
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EEFSEC RECQL5 TOM1 INTS1 HELZ2 CLASP2 SRGAP2 TFB2M TAF5 DDX6	1.24e-03	1497	74	10	31527615
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	IFT140 DAW1 ACAN	1.29e-03	100	74	3	25807483
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PPP3CB UBR5 TOM1 INTS1 TFB2M XRCC5 DDX6 CDK4 PNP	1.37e-03	1257	74	9	37317656
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	UBR5 HELZ2 ADGRA2 STAB1	1.38e-03	225	74	4	12168954
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	PIKFYVE DNAH3 FEZF1 ZNF529	1.56e-03	233	74	4	37704626
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRA2 ADGRA3	1.75e-03	29	74	2	15203201
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	TOM1L2 ABCA2	1.75e-03	29	74	2	20167577
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	ZNF460 ZNF324 XRCC5	1.97e-03	116	74	3	21549307
Pubmed	Identification of interaction partners for individual SH3 domains of Fas ligand associated members of the PCH protein family in T lymphocytes.	MICALL1 SRGAP2	2.00e-03	31	74	2	19041431
Pubmed	Pooled-matrix protein interaction screens using Barcode Fusion Genetics.	ARNT BCL6 ZNF529 DDX6 CDK4	2.02e-03	419	74	5	27107012
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOM1L2 PPP3CB UBE2Q1 AEBP2 CLASP2 SRGAP2 TFB2M ANKRD50	2.12e-03	1084	74	8	11544199
Cytoband	1p34.2	SZT2 ZFP69B ZMYM6	1.06e-04	57	73	3	1p34.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF140 ZNF35 FEZF1 ZNF460 ZNF324 ZNF621 ZNF350 ZNF518B ZNF619 ZFP69B BCL6 SNAI3 ZNF529	3.84e-08	718	49	13	28
GeneFamily	Immunoglobulin like domain containing\|Adhesion G protein-coupled receptors, subfamily A	ADGRA2 ADGRA3	2.15e-05	3	49	2	911
Coexpression	GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN	TOM1L2 ZNF460 ZFP69B BCL6 DDX6 STAB1	1.87e-05	197	73	6	M8339
Coexpression	GSE17721_POLYIC_VS_CPG_16H_BMDC_DN	ASNSD1 PIKFYVE PPP3CB NUF2 TFB2M CDK4	2.04e-05	200	73	6	M3951
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A	MICALL1 ARNT RECQL5 TOM1 INTS1 ZNF324 ZNF350	3.17e-06	196	73	7	5005_DN
Disease	4-hydroxyphenylacetylglutamine measurement	DNAH3 ACSM3	1.71e-05	3	71	2	EFO_0800688
Disease	X-17676 measurement	DNAH3 ACSM3	1.58e-04	8	71	2	EFO_0800785
Disease	progression free survival, urinary bladder cancer	IFT140 AEBP2	3.71e-04	12	71	2	EFO_0004920, MONDO_0001187
Disease	adverse effect, response to xenobiotic stimulus	ABCA2 BCL6 ADARB2	3.94e-04	59	71	3	EFO_0009658, GO_0009410
Disease	beta-hydroxyisovalerate measurement	ACSM3 THEM5	5.10e-04	14	71	2	EFO_0800125
Disease	monocyte count	TOM1L2 PCED1A EEFSEC NEURL3 GALM UBE2Q1 SZT2 THEM5 NUF2 BCL6	1.19e-03	1320	71	10	EFO_0005091
Disease	lymphoma	BCL6 DDX6	1.52e-03	24	71	2	EFO_0000574
Disease	urinary uromodulin measurement	DNAH3 ACSM3 GRAMD1C	1.63e-03	96	71	3	EFO_0005663
Disease	neuroblastoma	ARHGEF40 SERPINB8 NUF2	2.79e-03	116	71	3	EFO_0000621
Disease	Global developmental delay	SZT2 INTS1 DDX6	4.09e-03	133	71	3	C0557874
Disease	severe acute respiratory syndrome, COVID-19	MICALL1 NTRK2 AEBP2 SRGAP2 ADARB2	4.48e-03	447	71	5	EFO_0000694, MONDO_0100096
Disease	autistic disorder (is_implicated_in)	PTCHD1 NTRK2	4.62e-03	42	71	2	DOID:12849 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VHCLVGFTLTHRRFN	NAT1	231	P18440
RHNIEGIFTFVDHRC	ARNT	366	P27540
EHRNRVFHDFRNGLC	DDX6	371	P26196
IRHRAICFNLSAHIE	AEBP2	406	Q6ZN18
HGRLFINRIFHISAD	GRAMD1C	326	Q8IYS0
FHRTHFLRELQGCAT	ARHGEF40	1136	Q8TER5
FRFVFSDQVHRLCLG	ACCS	456	Q96QU6
LGLFVFTHHCARRRD	ADGRA2	1061	Q96PE1
LSFSAFFVVHHCVNR	ADGRA3	1036	Q8IWK6
RGLHRQALAFHFCKA	ANKRD50	101	Q9ULJ7
IHRQFFSNCTVDRVH	RAMP3	96	O60896
CHAEVVARRAFLHFL	ADARB2	431	Q9NS39
CLLGRLTELRTFNHH	NR1H4	446	Q96RI1
CQEHAAVLLHRAFLV	INTS1	2151	Q8N201
TLTELRFHNQRHICG	LMOD1	416	P29536
LSGIINFIHFREACR	NUF2	121	Q9BZD4
VRQFCSGSGHHLVRF	PCED1A	96	Q9H1Q7
HTFRGHTAEIVCLSF	DAW1	171	Q8N136
FRDGLAFCAILHRHR	MICALL1	31	Q8N3F8
VLERLCVNGHFFHRS	MICAL1	706	Q8TDZ2
LSRHHAFCFRGISAV	ACAN	666	P16112
AIAHTANTFRLHFCG	OR9G4	171	Q8NGQ1
LFLCRHSSHRGVFLS	PORCN	86	Q9H237
HIRRFVHGQGCVQII	PIKFYVE	1281	Q9Y2I7
FCARVHHAASGRVLE	GALM	256	Q96C23
HHFGVRHRFCTQTLG	GUCD1	76	Q96NT3
LFGLCFFHAVVQERR	DNAH3	3671	Q8TD57
RGLDFLHANCIVHRD	CDK4	126	P11802
VRQFHGLLVKRFHCA	ABCA2	1436	Q9BZC7
VFLCRHVYDFRHGRI	BAHD1	761	Q8TBE0
TCGARFVQVAHLRAH	BCL6	606	P41182
QCLFSAHVLHLRGVL	ASNSD1	46	Q9NWL6
CLQGFVGREVLSFHR	CXorf38	31	Q8TB03
QVQRSHCGHFLEVAR	HELZ2	1861	Q9BYK8
STLFLLRGNHECRHL	PPP3CB	151	P16298
HKFVICRLDQHIFSG	SDIM1	116	Q6ZPB5
ARDHFSLVRIHCFQG	IFT140	981	Q96RY7
IVARHCGLRVFGFSL	PNP	226	P00491
QVLVRFRHHNVYCSL	RTL1	751	A6NKG5
SRVCVHCHRNLGLIF	SYTL5	61	Q8TDW5
RIFAGHLADVNCTRF	TAF5	621	Q15542
FLHLTCSVRLRGQHS	SZT2	1566	Q5T011
LHRGLRTCFSRLGHF	PTCHD1	6	Q96NR3
GFRQASTLCRHKIIH	FEZF1	296	A0PJY2
FHLLKHCFGRRSATV	TFB2M	321	Q9H5Q4
FIRHHKTNCILFCGR	SERPINB8	356	P50452
RQLHCHLQVGRVFTC	SNAI3	171	Q3KNW1
RHAKCFQRLAIFGSV	ACSM3	11	Q53FZ2
FRFAQLCGLHIVIHA	CLTCL1	1266	P53675
SGCAAIRFIIRHTHV	CLASP2	196	O75122
HFVHRDLATRNCLVG	NTRK2	671	Q16620
LIRHFFHGRARCESE	RECQL5	966	O94762
GKAFSCFSHLIVHQR	ZNF35	396	P13682
DIHTNTCRLAFHGIL	EEFSEC	436	P57772
AFCRTTNLIRHFSIH	ZNF460	456	Q14592
CGRAFRERPALFHHQ	ZNF324	486	O75467
MIRRCFQVAARLGHH	THEM5	1	Q8N1Q8
CGHRFHVLVASQDFV	TOM1	81	O60784
CIRFISRHGLQHEGI	SRGAP2	511	O75044
RAHRQLVFRYHVVGC	STAB1	1636	Q9NY15
CIAHRRTTFHDGIVF	NEURL3	36	Q96EH8
GFIQKTCLIAHQRFH	ZNF350	326	Q9GZX5
AFGCRSLFIVHQRIH	ZNF621	271	Q6ZSS3
AFTHCFIHRERLVAE	ZMYM6	1006	O95789
CGKAFFQIRHLRQHE	ZFP69B	396	Q9UJL9
CGKAFRRFSHLTRHQ	ZNF140	306	P52738
FCGKSFRVHAQLTRH	ZNF529	286	Q6P280
CGHRFHILVANRDFI	TOM1L2	81	Q6ZVM7
FRGHTFIINCIQVHG	WDR86	311	Q86TI4
ERHVHRLECNGVIFT	ZNF619	61	Q8N2I2
RFQRLFQCLLHRALH	XRCC5	486	P13010
FISHRCDGNRNILHA	UBR5	911	O95071
IFHRGHERFRIASAC	UBE2Q1	51	Q7Z7E8
CQLGIRRHHVRLTYQ	ZNF518B	981	Q9C0D4