Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24	1.34e-13	37	32	7	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24	1.64e-13	38	32	7	GO:0070001
GeneOntologyMolecularFunction	endopeptidase activity	ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 USP9X	2.90e-07	430	32	8	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	ERVK-8 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 USP9Y ERVK-24 USP9X	5.86e-07	654	32	9	GO:0008233
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-8 ERVK-6 ERVK-7	6.11e-07	11	32	3	GO:0004523
GeneOntologyMolecularFunction	structural molecule activity	ERVK-8 LAMA2 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 IGF1R ERVK-9 ERVK-24	7.84e-07	891	32	10	GO:0005198
GeneOntologyMolecularFunction	zinc ion binding	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 SEC24A NR1H4	7.84e-07	891	32	10	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 LOXL2 SEC24A NR1H4	1.29e-06	1189	32	11	GO:0046914
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-8 ERVK-6 ERVK-7	1.34e-06	14	32	3	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-8 ERVK-6 ERVK-7	4.88e-06	21	32	3	GO:0035613
GeneOntologyMolecularFunction	protein-hormone receptor activity	ADIPOR1 IGF1R ADIPOR2	5.64e-06	22	32	3	GO:0016500
GeneOntologyMolecularFunction	adiponectin binding	ADIPOR1 ADIPOR2	7.46e-06	3	32	2	GO:0055100
GeneOntologyMolecularFunction	adipokinetic hormone receptor activity	ADIPOR1 ADIPOR2	1.49e-05	4	32	2	GO:0097003
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-8 ERVK-6 ERVK-7	2.80e-05	37	32	3	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-8 ERVK-6 ERVK-7	3.04e-05	38	32	3	GO:0034061
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-8 ERVK-6 ERVK-7	5.42e-05	46	32	3	GO:0016893
GeneOntologyMolecularFunction	co-SMAD binding	USP9Y USP9X	1.63e-04	12	32	2	GO:0070410
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-8 ERVK-6 ERVK-7	2.72e-04	79	32	3	GO:0004521
GeneOntologyMolecularFunction	hormone binding	ADIPOR1 IGF1R ADIPOR2	5.93e-04	103	32	3	GO:0042562
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-8 ERVK-6 ERVK-7	1.33e-03	136	32	3	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity	ERVK-8 ERVK-6 ERVK-7	1.33e-03	136	32	3	GO:0004519
GeneOntologyMolecularFunction	transcription coregulator binding	RUNX1 NFATC1 NR1H4	1.44e-03	140	32	3	GO:0001221
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-8 ERVK-6 ERVK-7	1.82e-03	152	32	3	GO:0016779
GeneOntologyMolecularFunction	transcription coactivator binding	RUNX1 NFATC1	3.38e-03	54	32	2	GO:0001223
GeneOntologyMolecularFunction	nuclease activity	ERVK-8 ERVK-6 ERVK-7	5.92e-03	231	32	3	GO:0004518
GeneOntologyMolecularFunction	SMAD binding	USP9Y USP9X	8.36e-03	86	32	2	GO:0046332
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-8 ERVK-6 ERVK-7	8.36e-03	262	32	3	GO:0140097
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9 IL4R	7.22e-09	85	36	6	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9 IL4R	7.22e-09	85	36	6	GO:0000768
GeneOntologyBiologicalProcess	syncytium formation	ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9 IL4R	9.55e-09	89	36	6	GO:0006949
GeneOntologyBiologicalProcess	viral process	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24	1.07e-06	464	36	8	GO:0016032
GeneOntologyBiologicalProcess	DNA integration	ERVK-8 ERVK-6 ERVK-7	1.38e-06	13	36	3	GO:0015074
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9 RUNX1 NFATC1 PTPRM IL4R LOXL2 ADIPOR2	2.87e-05	1483	36	11	GO:0048646
GeneOntologyBiologicalProcess	positive regulation of cold-induced thermogenesis	ADIPOR1 IGF1R IL4R ADIPOR2	2.94e-05	102	36	4	GO:0120162
GeneOntologyBiologicalProcess	immunoglobulin production	IGLV8-61 IGLV5-48 IGLV5-45 IL4R IGLV5-37	5.86e-05	241	36	5	GO:0002377
GeneOntologyBiologicalProcess	adiponectin-activated signaling pathway	ADIPOR1 ADIPOR2	6.19e-05	7	36	2	GO:0033211
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-8 ERVK-6 ERVK-7	8.00e-05	48	36	3	GO:0000731
GeneOntologyBiologicalProcess	regulation of cold-induced thermogenesis	ADIPOR1 IGF1R IL4R ADIPOR2	1.39e-04	152	36	4	GO:0120161
GeneOntologyBiologicalProcess	cold-induced thermogenesis	ADIPOR1 IGF1R IL4R ADIPOR2	1.54e-04	156	36	4	GO:0106106
GeneOntologyBiologicalProcess	adaptive thermogenesis	ADIPOR1 IGF1R IL4R ADIPOR2	2.44e-04	176	36	4	GO:1990845
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	IGF1R RUNX1 USP9Y NFATC1 USP9X	2.77e-04	336	36	5	GO:0071560
GeneOntologyBiologicalProcess	response to transforming growth factor beta	IGF1R RUNX1 USP9Y NFATC1 USP9X	3.05e-04	343	36	5	GO:0071559
GeneOntologyBiologicalProcess	temperature homeostasis	ADIPOR1 IGF1R IL4R ADIPOR2	3.67e-04	196	36	4	GO:0001659
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-8 ERVK-6 ERVK-7	4.08e-04	83	36	3	GO:0006278
GeneOntologyBiologicalProcess	adaptive immune response	TRAV8-4 IGLV8-61 IGLV5-48 TRAV6 IGLV5-45 IL4R IGLV5-37	5.30e-04	838	36	7	GO:0002250
GeneOntologyBiologicalProcess	DNA biosynthetic process	ERVK-8 ERVK-6 ERVK-7 NFATC1	5.48e-04	218	36	4	GO:0071897
GeneOntologyBiologicalProcess	production of molecular mediator of immune response	IGLV8-61 IGLV5-48 IGLV5-45 IL4R IGLV5-37	6.36e-04	403	36	5	GO:0002440
GeneOntologyBiologicalProcess	positive regulation of secretion by cell	SLC6A4 RUNX1 IL4R SEC24A NR1H4	6.43e-04	404	36	5	GO:1903532
GeneOntologyCellularComponent	immunoglobulin complex	IGLV8-61 IGLV5-48 IGLV5-45 IGLV5-37	2.06e-04	166	37	4	GO:0019814
Domain	AdipoR/HlyIII-related	ADIPOR1 ADIPOR2	9.39e-05	11	25	2	IPR004254
Domain	HlyIII	ADIPOR1 ADIPOR2	9.39e-05	11	25	2	PF03006
Domain	Galactose-bd-like	LAMA2 PTPRM GLB1L	2.62e-04	94	25	3	IPR008979
Domain	zf-CCHC	ERVK-5 ERVK-6	4.28e-04	23	25	2	PF00098
Domain	ZF_CCHC	ERVK-5 ERVK-6	9.96e-04	35	25	2	PS50158
Domain	FN3	IGF1R PTPRM IL4R	1.87e-03	185	25	3	SM00060
Domain	p53-like_TF_DNA-bd	RUNX1 NFATC1	2.27e-03	53	25	2	IPR008967
Domain	FN3	IGF1R PTPRM IL4R	2.31e-03	199	25	3	PS50853
Domain	ZnF_C2HC	ERVK-5 ERVK-6	2.45e-03	55	25	2	SM00343
Domain	Znf_CCHC	ERVK-5 ERVK-6	2.45e-03	55	25	2	IPR001878
Domain	FN3_dom	IGF1R PTPRM IL4R	2.65e-03	209	25	3	IPR003961
Domain	Retrov_capsid_C	ERVK-5 ERVK-6	2.81e-03	59	25	2	IPR008916
Domain	USP_CS	USP9Y USP9X	3.50e-03	66	25	2	IPR018200
Domain	USP_1	USP9Y USP9X	3.93e-03	70	25	2	PS00972
Domain	UCH	USP9Y USP9X	4.04e-03	71	25	2	PF00443
Domain	USP_2	USP9Y USP9X	4.04e-03	71	25	2	PS00973
Domain	USP_3	USP9Y USP9X	4.15e-03	72	25	2	PS50235
Domain	USP_dom	USP9Y USP9X	4.15e-03	72	25	2	IPR028889
Domain	Peptidase_C19_UCH	USP9Y USP9X	4.15e-03	72	25	2	IPR001394
Domain	-	LAMA2 GLB1L	4.26e-03	73	25	2	2.60.120.260
Domain	ARM-type_fold	CTIF USP9Y USP9X	1.01e-02	339	25	3	IPR016024
Domain	-	IGF1R NFATC1 PTPRM IL4R	1.10e-02	663	25	4	2.60.40.10
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	2.57e-05	6	19	2	MM14630
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	4.80e-05	8	19	2	M26990
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	7.70e-05	10	19	2	M39539
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	7.70e-05	10	19	2	MM15824
Pathway	WP_TH17_CELL_DIFFERENTIATION_PATHWAY	RUNX1 NFATC1 IL4R	1.03e-04	69	19	3	M45541
Pathway	WP_ULCERATIVE_COLITIS_SIGNALING	NFATC1 IL4R	2.60e-04	18	19	2	M45536
Pathway	BIOCARTA_HDAC_PATHWAY	IGF1R NFATC1	5.07e-04	25	19	2	M1547
Pathway	BIOCARTA_HDAC_PATHWAY	IGF1R NFATC1	5.49e-04	26	19	2	MM1371
Pathway	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	ATG14 SEC24A	6.84e-04	29	19	2	M1062
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-8 ERVK-5 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24	7.60e-14	94	37	8	21542922
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-8 ERVK-6 ERVK-19 ERVK-21 ERVK-9	8.10e-13	12	37	5	14557543
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-19 ERVK-7 ERVK-21	5.41e-12	5	37	4	12629516
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-24	4.43e-09	4	37	3	10469592
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-5 ERVK-6 ERVK-19	4.43e-09	4	37	3	7983737
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-5 ERVK-6 ERVK-7	1.11e-08	5	37	3	11401426
Pubmed	Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.	ERVK-6 ERVK-19 ERVK-9	2.21e-08	6	37	3	15063128
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVK-6 ERVK-19 ERVK-21	1.32e-07	10	37	3	12970426
Pubmed	Sequence and evolution of the human germline V lambda repertoire.	IGLV8-61 IGLV5-48 IGLV5-45 IGLV5-37	2.22e-07	49	37	4	8951372
Pubmed	Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.	RUNX1 USP9Y USP9X	2.42e-07	12	37	3	23861879
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-21 ERVK-9 ERVK-24	8.94e-07	18	37	3	18664271
Pubmed	Adiponectin receptor-1 expression is decreased in the pancreas of obese mice.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19062045
Pubmed	Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	20028965
Pubmed	Lack of any prognostic relationship between adiponectin receptor (Adipo R1/R2) expression for early/advanced stage gastric cancer.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	24969908
Pubmed	Adiponectin and adiponectin receptor in relation to colorectal cancer progression.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	21351255
Pubmed	Arterial stiffness is associated with increased monocyte expression of adiponectin receptor mRNA and protein in patients with coronary artery disease.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	22534793
Pubmed	Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15331527
Pubmed	Omental fat expression of adiponectin and adiponectin receptors in non-obese women with PCOS: a preliminary study.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19909601
Pubmed	The role of AdipoR1 and AdipoR2 in liver fibrosis.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	29237572
Pubmed	Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17416799
Pubmed	Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	28145500
Pubmed	AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	33420419
Pubmed	Adiponectin receptor expression predicts favorable prognosis in cases of hepatocellular carcinoma.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	24619866
Pubmed	Influence of insulin resistance on adiponectin receptor expression in breast cancer.	ADIPOR1 IGF1R	1.10e-06	2	37	2	19524379
Pubmed	Overexpression of adiponectin receptors potentiates the antiinflammatory action of subeffective dose of globular adiponectin in vascular endothelial cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18988888
Pubmed	Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19549705
Pubmed	Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25392268
Pubmed	Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18923878
Pubmed	Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15918014
Pubmed	The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18842004
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	1.10e-06	2	37	2	9060628
Pubmed	Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17216283
Pubmed	Dual action of adiponectin on insulin secretion in insulin-resistant mice.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15358228
Pubmed	Regulation of adiponectin receptor gene expression in diabetic mice.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15613685
Pubmed	Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16724230
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	1.10e-06	2	37	2	9460924
Pubmed	Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.	USP9Y USP9X	1.10e-06	2	37	2	12925892
Pubmed	Demonstration of adiponectin receptors 1 and 2 mRNA expression in human breast cancer cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17123704
Pubmed	AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	30890562
Pubmed	The regulation of adiponectin receptors in human prostate cancer cell lines.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16899222
Pubmed	Polymorphisms in adiponectin receptor genes are associated with lipodystrophy-related phenotypes in HIV-infected patients receiving antiretroviral therapy.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	26111083
Pubmed	Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17001470
Pubmed	Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	36429712
Pubmed	Expression of adiponectin receptors in mouse adrenal glands and the adrenocortical Y-1 cell line: adiponectin regulates steroidogenesis.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19878661
Pubmed	Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.	USP9Y USP9X	1.10e-06	2	37	2	12895410
Pubmed	Variations in ADIPOR1 But Not ADIPOR2 are Associated With Hypertriglyceridemia and Diabetes in an Admixed Latin American Population.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	29145541
Pubmed	AdipoR-increased intracellular ROS promotes cPLA2 and COX-2 expressions via activation of PKC and p300 in adiponectin-stimulated human alveolar type II cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	27288489
Pubmed	Adiponectin receptor expression in gastric carcinoma: implications in tumor development and progression.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	23358721
Pubmed	Expression profiles of adiponectin receptors in mouse embryos.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15939384
Pubmed	Expression and biologic significance of adiponectin receptors in papillary thyroid carcinoma.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	22907586
Pubmed	Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25892445
Pubmed	Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling properties.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	23255609
Pubmed	Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17716299
Pubmed	Low-abundant adiponectin receptors in visceral adipose tissue of humans and rats are further reduced in diabetic animals.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	20470935
Pubmed	Adipo-R1 and adipo-R2 expression in colorectal adenomas and carcinomas.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25640382
Pubmed	The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	33851685
Pubmed	Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17459059
Pubmed	Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18310295
Pubmed	The effect of renal transplantation on adiponectin and its isoforms and receptors.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17697862
Pubmed	Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	21186369
Pubmed	Expressions of adiponectin receptors in placenta and their correlation with preeclampsia.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19487733
Pubmed	Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18466348
Pubmed	Association of ADIPOR2 with liver function tests in type 2 diabetic subjects.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18719649
Pubmed	Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	18971219
Pubmed	Crystal structures of the human adiponectin receptors.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25855295
Pubmed	Adiponectin receptor signaling on dendritic cells blunts antitumor immunity.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25261236
Pubmed	Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15105989
Pubmed	Adiponectin receptors are downregulated in human gastric cancer.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	20336470
Pubmed	Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17327425
Pubmed	Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	24742672
Pubmed	Structural insights into adiponectin receptors suggest ceramidase activity.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	28329765
Pubmed	Localization of novel adiponectin receptor constructs.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17118803
Pubmed	in vitro Anti-Proliferative Effect of Adiponectin on Human Endometriotic Stromal Cells through AdipoR1 and AdipoR2 Gene Receptor Expression.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	26459399
Pubmed	Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16205883
Pubmed	Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16700915
Pubmed	A monoclonal antibody activating AdipoR for type 2 diabetes and nonalcoholic steatohepatitis.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	37948516
Pubmed	Expression of adiponectin receptors and its possible implication in the human endometrium.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16601138
Pubmed	AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	22000082
Pubmed	Adiponectin regulate growth hormone secretion via adiponectin receptor mediated Ca(2+) signalling in rat somatotrophs in vitro.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19500219
Pubmed	Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	17878241
Pubmed	Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16609881
Pubmed	Myocardial mitochondrial dysfunction in mice lacking adiponectin receptor 1.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25982881
Pubmed	Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	16505255
Pubmed	The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.	USP9Y USP9X	1.10e-06	2	37	2	8922996
Pubmed	Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	25575462
Pubmed	The distribution of adiponectin receptors on human peripheral blood mononuclear cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19120283
Pubmed	Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	19671624
Pubmed	Expression of adiponectin receptors in pancreatic beta cells.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	14651988
Pubmed	Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	32750056
Pubmed	Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish.	ADIPOR1 ADIPOR2	1.10e-06	2	37	2	15983228
Pubmed	Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	16678125
Pubmed	Identification of adiponectin and its receptors in human osteoblast-like cells and association of T45G polymorphism in exon 2 of adiponectin gene with lumbar spine bone mineral density in Korean women.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	17054465
Pubmed	Differential effects of adiponectin in osteoblast-like cells.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	24673523
Pubmed	The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	15757860
Pubmed	Adiponectin receptor binding proteins--recent advances in elucidating adiponectin signalling pathways.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	20875820
Pubmed	Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	21889885
Pubmed	Relationships of plasma adiponectin level and adiponectin receptors 1 and 2 gene expression to insulin sensitivity and glucose and fat metabolism in monozygotic and dizygotic twins.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	17426101
Pubmed	Evidence for decreased expression of APPL1 associated with reduced insulin and adiponectin receptors expression in PCOS patients.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	27075719
Pubmed	Adiponectin and its receptors are expressed in bone-forming cells.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	15454091
Pubmed	Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans.	ADIPOR1 ADIPOR2	3.30e-06	3	37	2	16955209
Cytoband	22q11.2	IGLV8-61 IGLV5-48 IGLV5-45 IGLV5-37	2.45e-06	120	36	4	22q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr22q11	IGLV8-61 IGLV5-48 IGLV5-45 IGLV5-37 RGL4	1.85e-05	419	36	5	chr22q11
Cytoband	1q22	GLMP ERVK-7	9.29e-04	57	36	2	1q22
GeneFamily	Adiponectin receptors\|Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	1.05e-06	2	19	2	293
GeneFamily	Immunoglobulin lambda locus at 22q11.2	IGLV8-61 IGLV5-48 IGLV5-45 IGLV5-37	2.01e-06	89	19	4	353
GeneFamily	Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	5.72e-05	11	19	2	930
GeneFamily	Ubiquitin specific peptidases	USP9Y USP9X	1.56e-03	56	19	2	366
GeneFamily	T-cell receptor alpha locus at 14q11.2	TRAV8-4 TRAV6	6.61e-03	117	19	2	371
GeneFamily	Fibronectin type III domain containing	IGF1R PTPRM	1.21e-02	160	19	2	555
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	SLC6A4 LAMA2 IL4R ADIPOR2	6.74e-06	190	29	4	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 RUNX1 USP9X LOXL2	7.62e-06	196	29	4	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 RUNX1 USP9X LOXL2	7.62e-06	196	29	4	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC6A4 PTPRM IL4R ADIPOR2	7.62e-06	196	29	4	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	SLC6A4 PTPRM IL4R ADIPOR2	7.77e-06	197	29	4	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	SLC6A4 PTPRM IL4R ADIPOR2	7.77e-06	197	29	4	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLC6A4 PTPRM IL4R ADIPOR2	8.25e-06	200	29	4	746e8f61411f8e68b988152ab36561991f716a0a
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SPATA20 ATG14 USP9Y	1.42e-04	157	29	3	542944030cd9b3f3559e64f9f6598694d74003c0
ToppCell	normal_Lung-B_lymphocytes-MALT_B_cells\|normal_Lung / Location, Cell class and cell subclass	IGLV8-61 IGLV5-48 IGLV5-45	1.48e-04	159	29	3	fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SLC6A4 RUNX1 ADIPOR2	1.51e-04	160	29	3	694bf1f1952bd8ab444819f533da24fa2b73f701
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 KIAA1549L GLB1L	1.74e-04	168	29	3	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LOXL2 NR1H4	1.77e-04	169	29	3	8bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LOXL2 NR1H4	1.77e-04	169	29	3	bb43abad2c049b7f4d307737347290e01b3339a3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 LOXL2 NR1H4	1.77e-04	169	29	3	5f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV8-61 IGLV5-48 IGLV5-45	1.90e-04	173	29	3	0ca2169a275404118038c0489a48062879488765
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGLV8-61 IGLV5-48 IGLV5-45	2.00e-04	176	29	3	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.00e-04	176	29	3	e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.03e-04	177	29	3	71919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGLV8-61 IGLV5-45 IGLV5-37	2.06e-04	178	29	3	2e51c1596022b7047994ee13c18375bad19a54a5
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KIAA1549L LOXL2	2.06e-04	178	29	3	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KIAA1549L LOXL2	2.06e-04	178	29	3	d348a9550db940d204706529759dc51e30506b5f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTIF PTPRM LOXL2	2.13e-04	180	29	3	544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGLV8-61 IGLV5-45 IGLV5-37	2.17e-04	181	29	3	e7d9910f6143055645b6f03b1018282e6c215f10
ToppCell	normal_Lymph_Node-B_lymphocytes-Plasma_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	IGLV8-61 IGLV5-48 IGLV5-37	2.17e-04	181	29	3	949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV8-61 IGLV5-48 IGLV5-45	2.17e-04	181	29	3	e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.24e-04	183	29	3	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.27e-04	184	29	3	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.27e-04	184	29	3	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.27e-04	184	29	3	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.27e-04	184	29	3	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	droplet-Lung-LUNG-1m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.31e-04	185	29	3	53a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.31e-04	185	29	3	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 IGF1R RUNX1	2.31e-04	185	29	3	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.35e-04	186	29	3	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.35e-04	186	29	3	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.38e-04	187	29	3	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.38e-04	187	29	3	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	SLC6A4 PTPRM ADIPOR2	2.38e-04	187	29	3	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	KIAA1549L PTPRM IL4R	2.38e-04	187	29	3	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D122\|Adult / Lineage, Cell type, age group and donor	SLC6A4 PTPRM ADIPOR2	2.42e-04	188	29	3	02a62888e9db29d20133eeca1686d302545a39c9
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGLV5-48 IGLV5-45 IGLV5-37	2.42e-04	188	29	3	6844cebca177fdf38b21a40d606230a033717a3a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.46e-04	189	29	3	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.46e-04	189	29	3	287e59104687fe1665232c52993889f0f2c97f17
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV5-48 IGLV5-45 SEC24A	2.46e-04	189	29	3	a1bda6ed5c52a5d33d229018cb5982cae6305533
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.46e-04	189	29	3	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	droplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.46e-04	189	29	3	6d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.46e-04	189	29	3	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.50e-04	190	29	3	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	droplet-Limb_Muscle\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX1 IL4R LOXL2	2.50e-04	190	29	3	06c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTIF PTPRM LOXL2	2.50e-04	190	29	3	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	SLC6A4 PTPRM ADIPOR2	2.50e-04	190	29	3	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	IGF1R USP9Y PTPRM	2.50e-04	190	29	3	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC6A4 IGF1R PTPRM	2.50e-04	190	29	3	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8\|bone_marrow / Manually curated celltypes from each tissue	USP9Y PTPRM TRAV6	2.54e-04	191	29	3	db7b8f8826bf19d6eeee14319570a9e6e99ab2cb
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMA2 KIAA1549L LOXL2	2.58e-04	192	29	3	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTIF PTPRM LOXL2	2.58e-04	192	29	3	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMA2 KIAA1549L LOXL2	2.58e-04	192	29	3	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 RUNX1 LOXL2	2.58e-04	192	29	3	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LOXL2 NR1H4	2.62e-04	193	29	3	64edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 IL4R LOXL2	2.66e-04	194	29	3	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA2 LOXL2 NR1H4	2.66e-04	194	29	3	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC6A4 PTPRM ADIPOR2	2.66e-04	194	29	3	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 IL4R LOXL2	2.66e-04	194	29	3	ee6b5fb4e993a4c0dc556091b8fefd56bdc70d8f
ToppCell	droplet-Lung-1m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC6A4 RUNX1 ADIPOR2	2.66e-04	194	29	3	d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCell	droplet-Lung-LUNG-1m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A4 RUNX1 ADIPOR2	2.66e-04	194	29	3	621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 IL4R LOXL2	2.70e-04	195	29	3	841fde528ecb293e07b5e00e499d1e9f0b0dce14
ToppCell	mLN-B_cell-B_cell_IgG_Plasma\|mLN / Region, Cell class and subclass	IGLV8-61 IGLV5-48 IGLV5-45	2.74e-04	196	29	3	03b79f237e4f7ebab46b277d05377569c6342cf7
ToppCell	mLN-(2)_B_cell-(21)_B_cell_IgG_Plasma\|mLN / shred on region, Cell_type, and subtype	IGLV8-61 IGLV5-48 IGLV5-45	2.74e-04	196	29	3	e8b12b046d42a58e6f4d9419ab05a5c55e764f34
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A4 IL4R ADIPOR2	2.78e-04	197	29	3	6ac8d3e3f573e3848ab33e4df66dfaf8f948ea6c
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A4 IL4R ADIPOR2	2.78e-04	197	29	3	e3be7758a92f12e0a423394822957e1b7f995110
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC6A4 PTPRM IL4R	2.82e-04	198	29	3	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	LAM-Endothelial-VasEndo-2\|Endothelial / Condition, Lineage and Cell class	SLC6A4 IL4R ADIPOR2	2.82e-04	198	29	3	92bccaec01f1dbb17d5efcba30f7f800f674ca96
ToppCell	ASK452-Endothelial-Endothelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	SLC6A4 PTPRM LOXL2	2.82e-04	198	29	3	e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-T-T_CD4\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TRAV8-4 TRAV6 RGL4	2.82e-04	198	29	3	8d86b5c875d4663ea4d61f50a4eaff1883d97641
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLC6A4 PTPRM ADIPOR2	2.86e-04	199	29	3	fff88d2bba262583bb726900ae01e44954b72eb9
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	SLC6A4 PTPRM LOXL2	2.86e-04	199	29	3	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	wk_15-18-Hematologic_Lymphocytic-T_&_ILC-CD4_T\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TRAV8-4 TRAV6 RGL4	2.86e-04	199	29	3	992bc4f0dc4189f18773c55976eb124c3827e08b
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLC6A4 PTPRM IL4R	2.86e-04	199	29	3	68412bc39639edc4045437d62548f7101b9f1989
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLC6A4 IL4R ADIPOR2	2.86e-04	199	29	3	772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial\|6m / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 RUNX1 LOXL2	2.90e-04	200	29	3	2cc98abf11f5b58707de45a2282f03d47f00f035
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	LAMA2 RUNX1 LOXL2	2.90e-04	200	29	3	0f7431f670f3a175377cefae3479403a881bb8fb
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF1R IL4R RGL4	2.90e-04	200	29	3	6beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF1R IL4R RGL4	2.90e-04	200	29	3	026495aa7f1e7528a01d9199475cfc393677fc60
ToppCell	distal-Endothelial-Capillary-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SLC6A4 IL4R ADIPOR2	2.90e-04	200	29	3	ab96d3d801373459a2503ccfb665dc3f43bfb5a1
Drug	saran	RUNX1 NFATC1 NR1H4	1.09e-05	38	26	3	CID000062706
Drug	Pesticides	IGF1R NFATC1 IGLV8-61 ADIPOR2	2.42e-05	150	26	4	ctd:D010575
Drug	Chlorpromazine	RUNX1 NFATC1 GLB1L NR1H4 ADIPOR2 BAG4	3.40e-05	564	26	6	ctd:D002746
Drug	pinoline	SLC6A4 LOXL2	4.49e-05	9	26	2	CID000001868
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; PC3; HT_HG-U133A	RUNX1 LOXL2 GLB1L NR1H4	6.21e-05	191	26	4	3811_DN
Drug	Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; HL60; HG-U133A	IGF1R RUNX1 NFATC1 CANT1	6.60e-05	194	26	4	1404_UP
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	SPATA20 RUNX1 NFATC1 IL4R	6.73e-05	195	26	4	6163_DN
Drug	Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A	CTIF RUNX1 LOXL2 NR1H4	6.73e-05	195	26	4	3812_DN
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A	LAMA2 CTIF RUNX1 LOXL2	6.73e-05	195	26	4	3821_DN
Drug	Fusaric acid [536-69-6]; Up 200; 22.4uM; PC3; HT_HG-U133A	RUNX1 KIAA1549L USP9Y GLB1L	6.86e-05	196	26	4	3986_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A	CTIF IGF1R RUNX1 LOXL2	6.86e-05	196	26	4	6027_UP
Drug	Ribavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A	IL4R LOXL2 GLB1L SEC24A	6.86e-05	196	26	4	6018_UP
Drug	aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A	IGF1R RUNX1 CANT1 IL4R	7.00e-05	197	26	4	1145_DN
Drug	Dydrogesterone [152-62-5]; Up 200; 12.8uM; PC3; HT_HG-U133A	CTIF RUNX1 LOXL2 GLB1L	7.00e-05	197	26	4	4254_UP
Drug	Indoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A	LAMA2 RUNX1 USP9Y GLB1L	7.00e-05	197	26	4	4249_UP
Drug	PHA-00851261E [724719-49-7]; Up 200; 10uM; MCF7; HT_HG-U133A	CTIF RUNX1 PTPRM LOXL2	7.00e-05	197	26	4	3965_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A	CTIF IGF1R RUNX1 LOXL2	7.00e-05	197	26	4	5605_UP
Drug	Khellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A	CTIF IGF1R RUNX1 LOXL2	7.14e-05	198	26	4	6641_DN
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A	CTIF RUNX1 GLB1L BAG4	7.14e-05	198	26	4	3237_UP
Drug	Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	LAMA2 RUNX1 USP9Y LOXL2	7.14e-05	198	26	4	4145_UP
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; HL60; HT_HG-U133A	SPATA20 CTIF RUNX1 NFATC1	7.14e-05	198	26	4	2387_UP
Drug	Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; HL60; HG-U133A	IGF1R CANT1 SEC24A BAG4	7.14e-05	198	26	4	1551_UP
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; PC3; HT_HG-U133A	IGF1R PTPRM IL4R BAG4	7.14e-05	198	26	4	6329_DN
Drug	Pirlindole mesylate [60762-57-4]; Down 200; 12.4uM; HL60; HT_HG-U133A	LAMA2 SPATA20 RUNX1 IL4R	7.28e-05	199	26	4	3140_DN
Drug	Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A	CTIF RUNX1 LOXL2 GLB1L	7.28e-05	199	26	4	3891_DN
Drug	Tolazoline hydrochloride [59-97-2]; Up 200; 20.4uM; MCF7; HT_HG-U133A	RUNX1 NFATC1 USP9X SEC24A	7.28e-05	199	26	4	1500_UP
Drug	Flurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A	IGF1R USP9Y GLB1L NR1H4	7.42e-05	200	26	4	5634_UP
Drug	viloxazine	SLC6A4 LOXL2	8.22e-05	12	26	2	CID000005666
Drug	mazindol	SLC6A4 NFATC1 LOXL2	8.79e-05	76	26	3	CID000004020
Drug	Aurothioglucose	ADIPOR1 ADIPOR2	9.71e-05	13	26	2	ctd:D006051
Drug	ddTTP	ERVK-6 IGF1R IL4R	1.27e-04	86	26	3	CID000065051
Drug	picropodophyllin	IGF1R NR1H4	1.30e-04	15	26	2	ctd:C415032
Drug	Ar 1	ADIPOR1 ADIPOR2	1.69e-04	17	26	2	CID000009027
Drug	protriptyline	SLC6A4 LOXL2	1.90e-04	18	26	2	CID000004976
Drug	p-methoxyamphetamine	SLC6A4 LOXL2	2.12e-04	19	26	2	CID000031721
Drug	4-methylthioamphetamine	SLC6A4 LOXL2	2.12e-04	19	26	2	CID000151900
Drug	AC1L1GHZ	ERVK-6 IGF1R	2.35e-04	20	26	2	CID000003691
Drug	cis-9, trans-11-conjugated linoleic acid	ADIPOR1 ADIPOR2	3.13e-04	23	26	2	ctd:C503589
Drug	compound 23	SLC6A4 ERVK-6	3.41e-04	24	26	2	CID000447410
Drug	beta-CIT	SLC6A4 CANT1	3.41e-04	24	26	2	CID000108220
Drug	allene	ERVK-6 IGF1R	3.70e-04	25	26	2	CID000006335
Drug	acadesine	ADIPOR1 IGF1R ADIPOR2	3.92e-04	126	26	3	CID000017513
Drug	Ro 4-1284	SLC6A4 LOXL2	4.01e-04	26	26	2	CID000009345
Drug	tert-butyl hydroperoxide	SPATA20 NFATC1 IL4R LOXL2 NR1H4 ADIPOR2	4.43e-04	902	26	6	CID000006410
Drug	phentermine	SLC6A4 LOXL2	4.65e-04	28	26	2	CID000004771
Drug	iprindole	SLC6A4 LOXL2	4.65e-04	28	26	2	CID000021722
Drug	amfonelic acid	SLC6A4 LOXL2	5.00e-04	29	26	2	CID000002137
Drug	milnacipran	SLC6A4 LOXL2	5.35e-04	30	26	2	CID000055480
Drug	tianeptine	SLC6A4 LOXL2	5.35e-04	30	26	2	CID000068870
Drug	mitotane	IGF1R CANT1	5.71e-04	31	26	2	CID000004211
Drug	O1-Pentyl-Mannose	IGF1R NFATC1	5.71e-04	31	26	2	CID000113556
Drug	AC1L3JHX	SLC6A4 RUNX1 IL4R	6.03e-04	146	26	3	CID000090206
Drug	AC1Q5H8E	IGF1R PTPRM IL4R	6.39e-04	149	26	3	CID000114813
Drug	rhamnose	IGF1R PTPRM IL4R GLB1L	6.69e-04	356	26	4	CID000000840
Drug	11-R	SLC6A4 NFATC1	7.29e-04	35	26	2	CID016058680
Drug	T1 d	RUNX1 IL4R ADIPOR2	7.86e-04	160	26	3	CID004369451
Drug	NSC311040	USP9Y USP9X	8.15e-04	37	26	2	CID000329293
Drug	Calcort	LAMA2 NFATC1	8.60e-04	38	26	2	CID000026709
Drug	Digoxin [20830-75-5]; Up 200; 5.2uM; HL60; HT_HG-U133A	LAMA2 RUNX1 SEC24A	9.37e-04	170	26	3	2423_UP
Drug	tetrabenazine	SLC6A4 LOXL2	9.52e-04	40	26	2	CID000006018
Drug	M-K-R	IGF1R ADIPOR2	9.52e-04	40	26	2	CID011662966
Drug	topa quinone	SLC6A4 LOXL2	9.52e-04	40	26	2	CID000123871
Drug	doxepin	SLC6A4 LOXL2	9.52e-04	40	26	2	CID000003158
Drug	vicriviroc	ERVK-6 IL4R	1.10e-03	43	26	2	CID003009355
Drug	nefazodone	SLC6A4 LOXL2	1.10e-03	43	26	2	CID000004449
Drug	Prenylamine lactate [69-43-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	LAMA2 RUNX1 LOXL2	1.11e-03	180	26	3	5070_UP
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; PC3; HT_HG-U133A	CTIF RUNX1 SEC24A	1.12e-03	181	26	3	4493_UP
Disease	obesity (biomarker_via_orthology)	ADIPOR1 IGF1R NR1H4 ADIPOR2	6.89e-06	147	25	4	DOID:9970 (biomarker_via_orthology)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	IGF1R NR1H4 ADIPOR2	2.27e-05	65	25	3	DOID:0080208 (biomarker_via_orthology)
Disease	hyperinsulinism (biomarker_via_orthology)	ADIPOR1 ADIPOR2	7.19e-05	15	25	2	DOID:2018 (biomarker_via_orthology)
Disease	non-alcoholic steatohepatitis (biomarker_via_orthology)	NR1H4 ADIPOR2	9.30e-05	17	25	2	DOID:0080547 (biomarker_via_orthology)
Disease	prostate adenocarcinoma (is_implicated_in)	ADIPOR1 IGF1R	1.30e-04	20	25	2	DOID:2526 (is_implicated_in)
Disease	blood chromium measurement	KIAA1549L PTPRM	2.21e-04	26	25	2	EFO_0007579
Disease	Subfertility, Female	ADIPOR1 ADIPOR2	2.57e-04	28	25	2	C0341869
Disease	Sterility, Postpartum	ADIPOR1 ADIPOR2	2.57e-04	28	25	2	C0038279
Disease	Female sterility	ADIPOR1 ADIPOR2	2.57e-04	28	25	2	C0917730
Disease	Female infertility	ADIPOR1 ADIPOR2	2.57e-04	28	25	2	C0021361
Disease	hyperuricemia	IGF1R NFATC1	3.58e-04	33	25	2	EFO_0009104
Disease	osteoarthritis (is_marker_for)	IGF1R IL4R	4.03e-04	35	25	2	DOID:8398 (is_marker_for)
Disease	liver cirrhosis (is_implicated_in)	SLC6A4 IGF1R	6.09e-04	43	25	2	DOID:5082 (is_implicated_in)
Disease	end stage renal disease (biomarker_via_orthology)	ADIPOR1 ADIPOR2	7.28e-04	47	25	2	DOID:783 (biomarker_via_orthology)
Disease	pancreatic ductal carcinoma (is_marker_for)	IGF1R IL4R	1.22e-03	61	25	2	DOID:3587 (is_marker_for)
Disease	mean platelet volume	SLC6A4 ATG14 ADIPOR1 RUNX1 NFATC1	1.46e-03	1020	25	5	EFO_0004584
Disease	Abnormality of refraction	LAMA2 IGF1R RUNX1 NFATC1	2.32e-03	673	25	4	HP_0000539
Disease	left ventricular structural measurement	IGF1R RUNX1	2.52e-03	88	25	2	EFO_0008205
Disease	childhood onset asthma	LAMA2 RUNX1 IL4R	2.75e-03	334	25	3	MONDO_0005405
Disease	Inhalant adrenergic use measurement	RUNX1 IL4R	2.99e-03	96	25	2	EFO_0009941
Disease	pancreatic cancer (is_marker_for)	IL4R BAG4	3.31e-03	101	25	2	DOID:1793 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EQPPYPSYNSNYWNS	BAG4	91	O95429
NSWNPLTPPITQYYN	CTIF	576	O43310
PWISLPNNGDYSAYY	ATG14	266	Q6ZNE5
FVPWLYYSFYCNPQP	ADIPOR2	231	Q86V24
YYSNLGFYPQQPEEW	NR1H4	76	Q96RI1
SYNIYWYQQKPGSPP	IGLV5-37	51	A0A075B6J1
VPWLYYSFYCSPQPR	ADIPOR1	221	Q96A54
QYDSWPHYPEYFQQP	LOXL2	26	Q9Y4K0
QAPANWYNDTYPLSP	CANT1	81	Q8WVQ1
WNPPSLPNGNLSYYI	IGF1R	631	P08069
SNYSYPYASPQTSPW	NFATC1	191	O95644
QALPHSYYWSAPAPY	LAMA2	576	P24043
YFIPTPPSSYRNQAW	KIAA1549L	1726	Q6ZVL6
SYYPSWYQQTPGQAP	IGLV8-61	56	A0A075B6I0
LFNWPPENTSVYYQP	RGL4	66	Q8IZJ4
PPVAYQYWPPAELQY	ERVK-19	206	Q9YNA8
PPVAYQYWPPAELQY	ERVK-21	206	P62683
PPVAYQYWPPAELQY	ERVK-24	206	P63145
PPVAYQYWPPAELQY	ERVK-5	206	Q9HDB9
PPVAYQYWPPAELQY	ERVK-6	206	Q7LDI9
PPVAYQYWPPAELQY	ERVK-7	206	P63130
PPVAYQYWPPAELQY	ERVK-8	206	P62685
PPVAYQYWPPAELQY	ERVK-9	206	P63126
PPVAYQYWPPAELQY	HERVK_113	206	P62684
LTWSNPYPPDNYLYN	IL4R	141	P24394
YVPWNYHEPQPGVYN	GLB1L	81	Q6UWU2
AAANYTNWAYVPFPP	ERVK-21	96	P61565
PYPPYSLADFSWNNI	GLMP	146	Q8WWB7
NKTYNGYWNTPLLPY	PTPRM	681	P28827
SYRIYWYQQKPGSPP	IGLV5-48	51	A0A075B6I7
IQPSPPWSYDQSYQY	RUNX1	246	Q01196
YTGNPQYTYNNWSPP	USP9X	2431	Q93008
TYRIYWYQQKPGSPP	IGLV5-45	51	A0A087WSX0
NLPPPLNWQYNYPST	SEC24A	131	O95486
PPVAYQYWPPAELQY	ERVK-9	206	P63128
SSVPPYLFWYVQYPN	TRAV8-4	46	P01737
PYLLQHAYNPVDWYP	SPATA20	71	Q8TB22
PYTGNPQYSYNNWSP	USP9Y	2431	O00507
PQLRLFQYNYPYWSI	SLC6A4	561	P31645
NYSPAYLQWYRQDPG	TRAV6	66	A0A075B6T7