Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1D CACNA1G	5.28e-06	5	163	3	GO:0086007
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved SA node cell action potential	CACNA1D CACNA1G	6.62e-05	2	163	2	GO:0086059
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1D CACNA1G	1.82e-04	14	163	3	GO:0008331
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in AV node cell action potential	CACNA1C CACNA1G	1.98e-04	3	163	2	GO:0086056
GeneOntologyBiologicalProcess	regulation of DNA damage checkpoint	WDR76 FEM1B BRCA1 BRCA2 ETAA1	1.19e-06	24	166	5	GO:2000001
GeneOntologyBiologicalProcess	postreplication repair	REV3L USP10 BRCA1 SPRTN REV1	1.29e-05	38	166	5	GO:0006301
GeneOntologyBiologicalProcess	DNA replication	REV3L FANCM ESCO1 ORC2 BRCA1 TBRG1 BRCA2 NFRKB ETAA1 ANKRD17 REV1	4.69e-05	312	166	11	GO:0006260
GeneOntologyBiologicalProcess	translesion synthesis	REV3L USP10 SPRTN REV1	5.27e-05	26	166	4	GO:0019985
GeneOntologyBiologicalProcess	regulation of cell cycle checkpoint	WDR76 FEM1B BRCA1 BRCA2 ETAA1	6.09e-05	52	166	5	GO:1901976
GeneOntologyCellularComponent	chromatin	POU6F2 SATB2 BAZ2B TRPS1 GON4L SRCAP WDR76 FANCM EZH2 CREBBP ESCO1 CREM FOXR2 ORC2 YEATS2 PPARGC1A HOXD13 NFATC3 KLF5 NFRKB ANKRD17 MYOCD SPRTN NFAT5 FOXK1 TBP	1.20e-04	1480	167	26	GO:0000785
HumanPheno	Short long bone	DYNC2H1 TRPS1 ZNF407 SRCAP FANCM EZH2 KIAA0753 IARS2 BRCA1 BRCA2 HOXD13 UBAP2L ASXL2	1.47e-05	278	60	13	HP:0003026
HumanPheno	Cafe-au-lait spot	PLXND1 REV3L FANCM CREBBP USF3 BRCA1 BRCA2 UBAP2L CAPRIN1	2.61e-05	137	60	9	HP:0000957
HumanPheno	Abnormal long bone morphology	TPO SATB2 CENPE DYNC2H1 TRPS1 ZNF407 PLXND1 REV3L SRCAP FANCM EZH2 CREBBP KIAA0753 ZNF469 IARS2 BRCA1 BRCA2 HOXD13 UBAP2L KCNH1 ASXL2 HERC1	8.40e-05	821	60	22	HP:0011314
HumanPheno	Multiple cafe-au-lait spots	PLXND1 REV3L FANCM USF3 BRCA1 BRCA2	9.13e-05	64	60	6	HP:0007565
HumanPheno	Abnormal fingertip morphology	CFTR ZNF407 SRCAP FANCM EZH2 CREBBP RUSC2 BRCA1 BRCA2 CAPRIN1	1.07e-04	203	60	10	HP:0001211
HumanPheno	Abnormal morphology of bones of the upper limbs	SATB2 DYNC2H1 TRPS1 PLXND1 REV3L SRCAP FANCM EZH2 CREBBP KIAA0753 BRCA1 BRCA2 HOXD13 KCNH1 ASXL2	1.10e-04	436	60	15	HP:0040065
HumanPheno	Abnormality of thumb phalanx	SATB2 SRCAP FANCM EZH2 CREBBP BRCA1 BRCA2 HOXD13 UBAP2L KCNH1	1.16e-04	205	60	10	HP:0009602
HumanPheno	Thin upper lip vermilion	CACNA1C SATB2 CENPE TRPS1 ZNF407 SRCAP CREBBP BRCA1 UBAP2L SASS6 ANKRD17 ASXL2 CAPRIN1	1.18e-04	339	60	13	HP:0000219
HumanPheno	Thin lips	CACNA1C SATB2 CENPE TRPS1 ZNF407 SRCAP CREBBP BRCA1 UBAP2L SASS6 ANKRD17 ASXL2 CAPRIN1	1.18e-04	339	60	13	HP:0000213
HumanPheno	Abnormal toe phalanx morphology	SATB2 FANCM CREBBP KIAA0753 BRCA1 BRCA2 HOXD13 KCNH1	1.22e-04	130	60	8	HP:0010161
HumanPheno	Pyridoxine-responsive sideroblastic anemia	FANCM PNPO BRCA1 BRCA2	1.30e-04	23	60	4	HP:0005522
HumanPheno	Sclerosis of distal finger phalanx	TRPS1 SRCAP	1.36e-04	2	60	2	HP:0100915
HumanPheno	Ivory epiphyses of the distal phalanges of the hand	TRPS1 SRCAP	1.36e-04	2	60	2	HP:0010252
HumanPheno	Aplasia/hypoplasia involving forearm bones	DYNC2H1 PLXND1 REV3L FANCM BRCA1 BRCA2 HOXD13	1.50e-04	100	60	7	HP:0006503
HumanPheno	Triangular shaped phalanges of the hand	SATB2 SRCAP FANCM EZH2 CREBBP BRCA1 BRCA2 HOXD13 UBAP2L KCNH1	1.65e-04	214	60	10	HP:0009774
HumanPheno	Prominent fingertip pads	ZNF407 EZH2 CREBBP RUSC2 CAPRIN1	1.81e-04	46	60	5	HP:0001212
HumanPheno	Clinodactyly	SATB2 CENPE TRPS1 PLXND1 REV3L SRCAP FANCM EZH2 CREBBP KIAA0753 BRCA1 BRCA2 HOXD13 UBAP2L CACNA1G SPRTN CAPRIN1	2.21e-04	574	60	17	HP:0030084
HumanPheno	Prominent digit pad	ZNF407 EZH2 CREBBP RUSC2 CAPRIN1	2.22e-04	48	60	5	HP:0011298
HumanPheno	Abnormality of the tubular bones	SATB2 DYNC2H1 TRPS1 ZNF407 SRCAP FANCM EZH2 CREBBP KIAA0753 ZNF469 IARS2 BRCA1 BRCA2 HOXD13 UBAP2L KCNH1 ASXL2 HERC1	2.24e-04	632	60	18	HP:0100713
HumanPheno	Abnormality of the long tubular bones	SATB2 DYNC2H1 TRPS1 ZNF407 SRCAP FANCM EZH2 CREBBP KIAA0753 ZNF469 IARS2 BRCA1 BRCA2 HOXD13 UBAP2L KCNH1 ASXL2 HERC1	2.24e-04	632	60	18	HP:0100714
HumanPheno	Broad hallux	SATB2 CREBBP KIAA0753 HOXD13 UBAP2L KCNH1	2.39e-04	76	60	6	HP:0010055
HumanPheno	Varicocele	POU6F2 SRCAP BRCA2	3.17e-04	12	60	3	HP:0012871
HumanPheno	Abnormal upper limb bone morphology	SATB2 DYNC2H1 TRPS1 PLXND1 REV3L SRCAP FANCM EZH2 CREBBP KIAA0753 BRCA1 BRCA2 HOXD13 KCNH1 ASXL2	3.53e-04	484	60	15	HP:0040070
HumanPheno	Aplasia/Hypoplasia of the radius	PLXND1 REV3L FANCM BRCA1 BRCA2 HOXD13	3.62e-04	82	60	6	HP:0006501
HumanPheno	Thin vermilion border	CACNA1C SATB2 CENPE TRPS1 ZNF407 SRCAP CREBBP IARS2 BRCA1 UBAP2L SASS6 ANKRD17 ASXL2 CAPRIN1	3.77e-04	433	60	14	HP:0000233
Domain	DUF3697_Uba2	UBAP2 UBAP2L	7.85e-05	2	166	2	IPR022166
Domain	DUF3697	UBAP2 UBAP2L	7.85e-05	2	166	2	PF12478
Domain	VDCCAlpha1	CACNA1C CACNA1D CACNA1G	7.90e-05	10	166	3	IPR002077
Domain	CAC1F_C	CACNA1C CACNA1D	2.34e-04	3	166	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D	2.34e-04	3	166	2	PF16885
Domain	Helicase_C	TTF2 SRCAP FANCM DDX1 SUPV3L1 DDX60L	3.88e-04	107	166	6	PF00271
Domain	HELICc	TTF2 SRCAP FANCM DDX1 SUPV3L1 DDX60L	3.88e-04	107	166	6	SM00490
Domain	Helicase_C	TTF2 SRCAP FANCM DDX1 SUPV3L1 DDX60L	4.08e-04	108	166	6	IPR001650
Domain	HELICASE_CTER	TTF2 SRCAP FANCM DDX1 SUPV3L1 DDX60L	4.29e-04	109	166	6	PS51194
Domain	HELICASE_ATP_BIND_1	TTF2 SRCAP FANCM DDX1 SUPV3L1 DDX60L	4.29e-04	109	166	6	PS51192
Domain	VDCC_L_a1su	CACNA1C CACNA1D	4.66e-04	4	166	2	IPR005446
Domain	Ion_trans_dom	CACNA1C CACNA1D TRPM7 KCND2 KCNH1 CACNA1G	5.44e-04	114	166	6	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D TRPM7 KCND2 KCNH1 CACNA1G	5.44e-04	114	166	6	PF00520
Pathway	BIOCARTA_CARM_ER_PATHWAY	CREBBP PPARGC1A BRCA1 TBP	3.42e-05	26	102	4	M2499
Pubmed	Human transcription factor protein interaction networks.	SATB2 UBAP2 ATXN7L1 TRPS1 CCDC85C GON4L SRCAP CREBBP DDX1 YEATS2 BRCA1 NFATC3 UBAP2L KLF5 ZBTB21 NFRKB TNRC6A ANKRD17 SCAF11 ASXL2 QSER1 HERC1 PSMD14 CAPRIN1 FOXK1 MYB TBL1X TBP	4.97e-10	1429	172	28	35140242
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNA1C CPAMD8 POU6F2 ATXN7L1 DTNB TRPS1 CCDC85C GRIK1 CREBBP ESCO1 ANKRD44 YEATS2 USP10 USF3 PTPRJ ZNF544 MBNL2 UBAP2L RPTOR EEPD1 FECH ANKRD17 SCAF11 QSER1 NFAT5 MLPH TBL1X	5.49e-09	1489	172	27	28611215
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TTF2 FLNC SATB2 HIPK1 TRPS1 REV3L CREBBP CREM FOXR2 ORC2 PHKA2 IARS2 HOXD13 ZBTB21 ANKRD17 ASXL2 QSER1 FOXK1 TBL1X TBP	1.09e-08	857	172	20	25609649
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SLAIN2 TTF2 UBAP2 USP24 CCDC85C PTPN23 SRCAP CREBBP YEATS2 USP10 UBAP2L NFRKB QSER1 PEAK1 MAP4K4	1.12e-07	549	172	15	38280479
Pubmed	Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.	MAP3K1 BRCA1 BRCA2	1.19e-07	3	172	3	20809358
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BTBD8 HIPK1 GON4L CSMD3 RUSC2 FEM1B YEATS2 UBAP2L STARD9 NAV3 ASXL2 MAPKBP1 NFAT5	1.39e-07	407	172	13	12693553
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SLAIN2 FLNC SATB2 CREBBP DNTTIP2 YEATS2 USP10 BRCA2 UBAP2L ZBTB21 NFRKB CAPRIN1 FOXK1	3.73e-07	444	172	13	34795231
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DMTF1 GAS2L3 SPOPL PTPN23 SRCAP DNTTIP2 KIAA0753 FEM1B PPARGC1A UBAP2L KCNH1 FECH NFRKB ANKRD17 ASXL2 QSER1 PEAK1 HERC1 NFAT5 SLC29A1	4.79e-07	1084	172	20	11544199
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	SLAIN2 TTF2 GTSF1 SATB2 BAZ2B CREBBP DDX1 CCDC7 YEATS2 BRCA1 HOXD13 KLF5 ZBTB21 NFRKB ASXL2 QSER1 PSMD14 CAPRIN1 FOXK1 MYB	6.27e-07	1103	172	20	34189442
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TTF2 SATB2 DYNC2H1 TRPS1 GON4L EZH2 FAM90A1 CREBBP YEATS2 HOXD13 NFRKB FOXK1	7.81e-07	398	172	12	35016035
Pubmed	Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.	MAP3K1 BRCA1 BRCA2	1.18e-06	5	172	3	18355772
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DYNC2H1 BAZ2B PTPN23 ZNF407 FANCM ESCO1 KIAA0753 MYOF USF3 EEPD1 PEAK1 PLEKHH2 ZNF160	1.20e-06	493	172	13	15368895
Pubmed	ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2.	DDX1 USP10 UBAP2L TNRC6A CAPRIN1	1.23e-06	38	172	5	30629181
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SLAIN2 UAP1 UBAP2 TRPM7 CCDC85C DDX1 KIAA0753 RUSC2 NFATC3 STARD9 RPTOR ZBTB21 ANKRD17 PEAK1 MAP4K4 CNOT4 FOXK1	1.47e-06	861	172	17	36931259
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CENPE DYNC2H1 HIPK1 SRCAP CREBBP DDX1 YEATS2 BRCA2 NFATC3 RPTOR TNRC6A SASS6 SPRTN FOXK1	1.53e-06	588	172	14	38580884
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BAZ2B ATXN7L1 REV3L CREBBP YEATS2 BRCA1 BRCA2 ZBTB21 REV1	1.79e-06	222	172	9	37071664
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TTF2 VRK2 BAZ2B SRCAP WDR76 FANCM EZH2 ESCO1 CREM DNTTIP2 ORC2 YEATS2 BRCA1 TBRG1 KLF5 NFRKB SCAF11 ASXL2 QSER1 FOXK1 TBL1X	1.89e-06	1294	172	21	30804502
Pubmed	Breast cancer susceptibility variants alter risks in familial disease.	MAP3K1 BRCA1 BRCA2	2.35e-06	6	172	3	19617217
Pubmed	A census of human transcription factors: function, expression and evolution.	DMTF1 POU6F2 SATB2 TRPS1 GON4L EZH2 CREM FOXR2 YEATS2 USF3 HOXD13 NFATC3 KLF5 ZNF160 NFAT5 FOXK1 MYB	3.00e-06	908	172	17	19274049
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SLAIN2 ATXN7L1 TRPS1 REV3L SRCAP CREBBP DNTTIP2 YEATS2 ZNF469 MCTP1 BRCA1 RPTOR FECH ZBTB21 NFRKB TNRC6A ANKRD17 FOXK1 TBP	3.05e-06	1116	172	19	31753913
Pubmed	ETAA1 acts at stalled replication forks to maintain genome integrity.	FANCM BRCA1 BRCA2 ETAA1	3.24e-06	21	172	4	27723720
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1D CACNA1G	4.10e-06	7	172	3	12900400
Pubmed	Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization.	USP10 UBAP2L CAPRIN1	4.10e-06	7	172	3	32302570
Pubmed	Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2.	PTPRJ C5 MYB	4.10e-06	7	172	3	1347918
Pubmed	EZH2-CCF-cGAS Axis Promotes Breast Cancer Metastasis.	USP24 EZH2 USP10	4.10e-06	7	172	3	35163710
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	TTF2 POU6F2 TRPS1 ZNF407 EZH2 CREBBP ORC2 PPARGC1A BRCA1 BRCA2 HOXD13 NFATC3 MYOCD MYB TBL1X TBP	8.21e-06	877	172	16	20211142
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRPS1 CREBBP ORC2 KLF5 ZBTB21 NFRKB QSER1 FOXK1 TBL1X	8.24e-06	268	172	9	33640491
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	EZH2 DDX1 BRCA1 BRCA2 KLF5 QSER1 TBL1X	8.71e-06	146	172	7	23892456
Pubmed	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.	CREBBP ORC2 BRCA1 BRCA2	9.28e-06	27	172	4	17525332
Pubmed	Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.	REV3L BRCA1 BRCA2 REV1	1.08e-05	28	172	4	19661089
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BAZ2B SRCAP WDR76 EZH2 DNTTIP2 ORC2 BRCA1 HOXD13 ZBTB21 NFRKB SCAF11 QSER1 FOXK1	1.16e-05	608	172	13	36089195
Pubmed	The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.	ANKRD17 ASXL2 FOXK1	1.39e-05	10	172	3	19815555
Pubmed	Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.	MAP3K1 BRCA1 BRCA2	1.39e-05	10	172	3	37592023
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	SRCAP FANCM ESCO1 BRCA1 BRCA2 HERC1 REV1	1.40e-05	157	172	7	30686591
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SLAIN2 SATB2 UBAP2 PLXND1 USP10 RPTOR ZBTB21 TNRC6A ANKRD17 SCAF11 CACNA1G MAP4K4	1.42e-05	529	172	12	14621295
Pubmed	Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.	DYNC2H1 RHBDD2 TBRG1 PTPRJ	1.43e-05	30	172	4	27568566
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	FLNC EZH2 CREBBP	1.90e-05	11	172	3	24349473
Pubmed	Association of BRCA1/2 mutations with ovarian cancer prognosis: An updated meta-analysis.	BRCA1 BRCA2	2.43e-05	2	172	2	29480828
Pubmed	A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.	BRCA1 BRCA2	2.43e-05	2	172	2	17924331
Pubmed	Attitudes, knowledge, risk perceptions and decision-making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses.	BRCA1 BRCA2	2.43e-05	2	172	2	12833555
Pubmed	Randomised trial of a decision aid and its timing for women being tested for a BRCA1/2 mutation.	BRCA1 BRCA2	2.43e-05	2	172	2	14735173
Pubmed	Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.	BRCA1 BRCA2	2.43e-05	2	172	2	16032702
Pubmed	Oral contraceptive use and BRCA penetrance: a case-only study.	BRCA1 BRCA2	2.43e-05	2	172	2	19549808
Pubmed	Prevalence of BRCA1 and BRCA2 Mutations Among Patients With Ovarian, Primary Peritoneal, and Fallopian Tube Cancer in India: A Multicenter Cross-Sectional Study.	BRCA1 BRCA2	2.43e-05	2	172	2	34101484
Pubmed	Olaparib monotherapy in patients with advanced relapsed ovarian cancer and a germline BRCA1/2 mutation: a multistudy analysis of response rates and safety.	BRCA1 BRCA2	2.43e-05	2	172	2	26961146
Pubmed	Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study.	BRCA1 BRCA2	2.43e-05	2	172	2	20512419
Pubmed	Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus.	BRCA1 BRCA2	2.43e-05	2	172	2	37804357
Pubmed	Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.	BRCA1 BRCA2	2.43e-05	2	172	2	22053997
Pubmed	BRCA mutations in women with inflammatory breast cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	29044548
Pubmed	Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.	BRCA1 BRCA2	2.43e-05	2	172	2	33834176
Pubmed	Should genetic testing for BRCA1/2 be permitted for minors? Opinions of BRCA mutation carriers and their adult offspring.	BRCA1 BRCA2	2.43e-05	2	172	2	18200524
Pubmed	Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.	BRCA1 BRCA2	2.43e-05	2	172	2	29298688
Pubmed	Fertility in women with BRCA mutations: a case-control study.	BRCA1 BRCA2	2.43e-05	2	172	2	19200971
Pubmed	Prevalence of BRCA mutations and founder effect in high-risk Hispanic families.	BRCA1 BRCA2	2.43e-05	2	172	2	16030099
Pubmed	Prevalence of BRCA1 and BRCA2 large genomic rearrangements in Tunisian high risk breast/ovarian cancer families: Implications for genetic testing.	BRCA1 BRCA2	2.43e-05	2	172	2	28212807
Pubmed	Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	11448436
Pubmed	Rapid evolution of BRCA1 and BRCA2 in humans and other primates.	BRCA1 BRCA2	2.43e-05	2	172	2	25011685
Pubmed	Breast magnetic resonance imaging for screening high-risk women.	BRCA1 BRCA2	2.43e-05	2	172	2	23928241
Pubmed	Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	35980168
Pubmed	Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.	BRCA1 BRCA2	2.43e-05	2	172	2	11377596
Pubmed	BRCA mutations and risk of prostate cancer in Ashkenazi Jews.	BRCA1 BRCA2	2.43e-05	2	172	2	15131025
Pubmed	Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology.	CACNA1C EZH2	2.43e-05	2	172	2	29501388
Pubmed	Broad BRCA1 and BRCA2 mutational spectrum and high incidence of recurrent and novel mutations in the eastern Spain population.	BRCA1 BRCA2	2.43e-05	2	172	2	20033483
Pubmed	Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.	BRCA1 BRCA2	2.43e-05	2	172	2	28862356
Pubmed	BRCA1 and BRCA2 germline mutations in Moroccan breast/ovarian cancer families: novel mutations and unclassified variants.	BRCA1 BRCA2	2.43e-05	2	172	2	22425665
Pubmed	BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies.	BRCA1 BRCA2	2.43e-05	2	172	2	18752448
Pubmed	Peritoneal washing cytology in patients with BRCA1 or BRCA2 mutations undergoing risk-reducing salpingo-oophorectomies: a 10-year experience and reappraisal of its clinical utility.	BRCA1 BRCA2	2.43e-05	2	172	2	22425664
Pubmed	Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.	BRCA1 BRCA2	2.43e-05	2	172	2	22970155
Pubmed	Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study.	BRCA1 BRCA2	2.43e-05	2	172	2	34304065
Pubmed	Absence of 185delAG and 6174delT Mutations among Breast Cancer Patients of Eastern India.	BRCA1 BRCA2	2.43e-05	2	172	2	26625823
Pubmed	Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	26852015
Pubmed	Meta-analysis of BRCA1 and BRCA2 penetrance.	BRCA1 BRCA2	2.43e-05	2	172	2	17416853
Pubmed	Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment.	BRCA1 BRCA2	2.43e-05	2	172	2	18175183
Pubmed	Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients.	BRCA1 BRCA2	2.43e-05	2	172	2	38057686
Pubmed	Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.	BRCA1 BRCA2	2.43e-05	2	172	2	27914478
Pubmed	BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations.	BRCA1 BRCA2	2.43e-05	2	172	2	16455195
Pubmed	The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial.	BRCA1 BRCA2	2.43e-05	2	172	2	23810788
Pubmed	Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.	BRCA1 BRCA2	2.43e-05	2	172	2	29727326
Pubmed	Risk reducing surgery with peritoneal staging in BRCA1-2 mutation carriers. A prospective study.	BRCA1 BRCA2	2.43e-05	2	172	2	35871032
Pubmed	Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.	BRCA1 BRCA2	2.43e-05	2	172	2	22739995
Pubmed	The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study.	BRCA1 BRCA2	2.43e-05	2	172	2	27794048
Pubmed	Breast cancer surgery trend changes since the introduction of BRCA1/2 mutation screening: a retrospective cohort analysis of 158 mutation carriers treated at a single institution.	BRCA1 BRCA2	2.43e-05	2	172	2	20972632
Pubmed	BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients.	BRCA1 BRCA2	2.43e-05	2	172	2	19499246
Pubmed	Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.	BRCA1 BRCA2	2.43e-05	2	172	2	19656164
Pubmed	Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.	BRCA1 BRCA2	2.43e-05	2	172	2	15986445
Pubmed	Identification and characterization of human FOXK1 gene in silico.	FOXR2 FOXK1	2.43e-05	2	172	2	15202027
Pubmed	Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	18165636
Pubmed	Large genomic rearrangements in BRCA1 and BRCA2: implications for patient care.	BRCA1 BRCA2	2.43e-05	2	172	2	23615136
Pubmed	Clinicopathologic features and BRCA mutations in primary fallopian tube cancer in Japanese women.	BRCA1 BRCA2	2.43e-05	2	172	2	29982601
Pubmed	Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers.	BRCA1 BRCA2	2.43e-05	2	172	2	28343309
Pubmed	BRCA1 and BRCA2 genetic testing in Hispanic patients: mutation prevalence and evaluation of the BRCAPRO risk assessment model.	BRCA1 BRCA2	2.43e-05	2	172	2	17925560
Pubmed	Intratumor Heterogeneity of Homologous Recombination Deficiency in Primary Breast Cancer.	BRCA1 BRCA2	2.43e-05	2	172	2	27601588
Pubmed	Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers.	BRCA1 BRCA2	2.43e-05	2	172	2	23918944
Pubmed	Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms.	BRCA1 BRCA2	2.43e-05	2	172	2	33558422
Pubmed	Breast cancer risk associated with BRCA1/2 variants in the Pakistani population.	BRCA1 BRCA2	2.43e-05	2	172	2	30430339
Pubmed	Satisfaction with prophylactic risk-reducing salpingo-oophorectomy in BRCA mutation carriers is very high and little dependent on the participants' characteristics at surgery: a prospective study.	BRCA1 BRCA2	2.43e-05	2	172	2	33534430
Pubmed	BRCA 1, 2 mutation and earlier menopause: could BRCA 1,2 be used as predictor of menopause?	BRCA1 BRCA2	2.43e-05	2	172	2	34137566
Pubmed	BRCA1/2 Mutation Detection in the Tumor Tissue from Selected Polish Patients with Breast Cancer Using Next Generation Sequencing.	BRCA1 BRCA2	2.43e-05	2	172	2	33918338
Pubmed	Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mutation Carriers.	BRCA1 BRCA2	2.43e-05	2	172	2	26181175
Pubmed	Mutational analysis of BRCA1 and BRCA2 in Mediterranean Spanish women with early-onset breast cancer: identification of three novel pathogenic mutations.	BRCA1 BRCA2	2.43e-05	2	172	2	14517958
Interaction	HNF4A interactions	SATB2 TRPS1 SRCAP EZH2 CREBBP YEATS2 PPARGC1A ZBTB21 NFRKB ASXL2 QSER1 TBL1X TBP	5.16e-07	275	167	13	int:HNF4A
Interaction	CARD8 interactions	FLNC SRCAP YEATS2 BRCA2 HOXD13 NFRKB PEAK1	6.31e-07	60	167	7	int:CARD8
Interaction	FHL2 interactions	CACNA1C POU6F2 HIPK1 CFTR EZH2 CREBBP YEATS2 BRCA1 ANKRD17 ASXL2 QSER1 NFAT5 FOXK1 TBL1X REV1	1.12e-06	396	167	15	int:FHL2
Interaction	KIZ interactions	FANCM KIAA0753 TNRC6A SASS6 PSMD14	2.56e-06	27	167	5	int:KIZ
Interaction	HDAC1 interactions	SATB2 TRPM7 TRPS1 USP24 CCDC85C GON4L WDR76 EZH2 CREBBP ESCO1 CREM DDX1 YEATS2 ZNF800 BRCA1 BRCA2 KLF5 ZBTB21 TNRC6A ANKRD17 NUDCD1 CAPRIN1 FOXK1 TBL1X TBP	4.84e-06	1108	167	25	int:HDAC1
Interaction	H2BC21 interactions	BTBD8 ATXN7L1 SRCAP WDR76 EZH2 CREBBP ESCO1 DNTTIP2 ORC2 YEATS2 PPARGC1A USF3 BRCA1 SCAF11 DDX60L QSER1 PSMD14 MAP4K4 TBL1X	5.35e-06	696	167	19	int:H2BC21
Interaction	YTHDF3 interactions	UBAP2 CFTR DDX1 USP10 BRCA1 UBAP2L KLF5 TNRC6A ANKRD17 CAPRIN1 CNOT4	6.78e-06	246	167	11	int:YTHDF3
Interaction	UBAP2L interactions	UBAP2 EZH2 DDX1 YEATS2 USP10 BRCA1 UBAP2L RPTOR TNRC6A ANKRD17 CAPRIN1 CNOT4	7.48e-06	298	167	12	int:UBAP2L
Interaction	TP63 interactions	FLNC SATB2 CENPE PTPN23 YEATS2 BRCA1 BRCA2 KLF5 AGBL2 PSMD14 CAPRIN1 FOXK1	9.14e-06	304	167	12	int:TP63
Interaction	WWTR1 interactions	SLAIN2 TTF2 UBAP2 USP24 CCDC85C PTPN23 SRCAP CREBBP YEATS2 USP10 KLF5 QSER1 PEAK1 MAP4K4	1.18e-05	422	167	14	int:WWTR1
Interaction	FOXN1 interactions	TTF2 SATB2 HOXD13 MAPKBP1 TBP	1.91e-05	40	167	5	int:FOXN1
Interaction	CNOT9 interactions	UBAP2 KIAA0753 UBAP2L TNRC6A SASS6 ANKRD17 MAP4K4 CAPRIN1 CNOT4 MYB	2.37e-05	231	167	10	int:CNOT9
Interaction	DAZL interactions	UBAP2 DDX1 USP10 MBNL2 UBAP2L TNRC6A ANKRD17 CAPRIN1	2.86e-05	145	167	8	int:DAZL
Interaction	YWHAG interactions	SLAIN2 UAP1 UBAP2 TRPM7 CFTR USP24 CCDC85C EZH2 DNTTIP2 DDX1 MAP3K1 KIAA0753 RUSC2 IARS2 LRFN4 NFATC3 STARD9 RPTOR ZBTB21 ANKRD17 SCAF11 PEAK1 MAP4K4 CNOT4 FOXK1	3.63e-05	1248	167	25	int:YWHAG
Interaction	ZBTB10 interactions	ATXN7L1 DDX1 USP10 UBAP2L KLF5 TNRC6A CAPRIN1 MYB	3.82e-05	151	167	8	int:ZBTB10
Interaction	MEX3B interactions	UBAP2 DDX1 RUSC2 USP10 UBAP2L TNRC6A ANKRD17 CAPRIN1 CNOT4	1.01e-04	222	167	9	int:MEX3B
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCM BRCA1 BRCA2	2.08e-04	20	106	3	548
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	DMTF1 GON4L EZH2 MYB	2.62e-04	53	106	4	532
GeneFamily	Nuclear factors of activated T-cells	NFATC3 NFAT5	3.37e-04	5	106	2	665
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D CACNA1G	4.62e-04	26	106	3	253
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CPAMD8 C5	1.19e-03	9	106	2	1234
GeneFamily	X-linked mental retardation\|RNA helicases	FANCM SUPV3L1	1.81e-03	11	106	2	1168
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF134 TRPS1 ZNF407 ZNF251 ZNF800 ZNF469 ZNF713 ZNF544 KLF5 ZBTB21 ZNF160	3.25e-03	718	106	11	28
Coexpression	GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP	CACNA1D SATB2 VRK2 DTNB GON4L PLXND1 MYOF PTPRJ CNOT4 TBL1X	7.06e-07	200	168	10	M3901
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	ATXN7L1 MAP3K1 ACOD1 USF3 HERC1 NFAT5 MAP4K4 MYB TBL1X	3.84e-06	189	168	9	M3112
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	UBAP2 USP24 CREBBP YEATS2 BRCA1 HERC1 NFAT5 MAP4K4	2.21e-05	180	168	8	M8239
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	DMTF1 BAZ2B USP24 REV3L CREBBP FEM1B ORC2 NAV3 SCAF11 CNOT4	2.54e-05	300	168	10	M8702
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	SLAIN2 SATB2 SYT3 CENPE TRPM7 HIPK1 TRPS1 REV3L FANCM EZH2 KIAA0753 ORC2 ZNF800 IARS2 BRCA2 UBAP2L FECH ETAA1 BAMBI CACNA1G ASXL2 QSER1 NUDCD1 ZNF160 PLEKHO1 CNOT4	3.80e-06	1252	164	26	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	TTF2 MGAM GAS2L3 CENPE TRPM7 DTNB SRCAP CREBBP ESCO1 MAP3K1 PPARGC1A BRCA1 KCND2 UBAP2L KCNH1 TNRC6A ANKRD17 SCAF11 HERC1 CNOT4	4.32e-06	806	164	20	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000	CACNA1C POU6F2 SATB2 LRRC75B CENPE TRPS1 EZH2 CREBBP DDX1 RUSC2 ANKRD44 PPARGC1A MYOF PTPRJ BRCA2 KLF5 NAV3 PALM3 BAMBI CACNA1G QSER1 PEAK1	6.66e-06	978	164	22	Facebase_RNAseq_e10.5_Mandibular Arch_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	MGAM GAS2L3 CENPE TRPM7 TRPS1 GRIK1 SRCAP CREBBP ESCO1 MAP3K1 ZNF800 KCND2 UBAP2L ANKRD17 SCAF11 ASXL2 HERC1 NFAT5 CNOT4	1.51e-05	804	164	19	gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	DPEP1 MGAM LRRC75B GAS2L3 TRPS1 ADAMTS5 SRCAP CREBBP ESCO1 C4orf54 MAP3K1 ZNF800 STARD9 TNRC6A MYOCD SCAF11 HERC1 MLPH	4.64e-05	797	164	18	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	DPEP1 MGAM LRRC75B GAS2L3 TRPM7 TRPS1 GRIK1 SRCAP CREBBP ESCO1 MBNL2 STARD9 TNRC6A MYOCD SCAF11 HERC1 CNOT4 TBL1X	4.80e-05	799	164	18	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	TTF2 POU6F2 CENPE WDR76 EPB41L4A FANCM ESCO1 DNTTIP2 ZNF800 BRCA1 BRCA2 ETAA1 SCAF11 PLEKHO1	6.89e-05	532	164	14	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	CENPE TRPM7 TRPS1 REV3L WDR76 FANCM EZH2 DNTTIP2 ORC2 ZNF800 IARS2 BRCA1 BRCA2 SUPV3L1 ETAA1 SASS6 SCAF11 QSER1 NUDCD1 ZNF160 PSMD14 PLEKHO1 CNOT4	1.03e-04	1257	164	23	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500	POU6F2 CENPE TRPS1 REV3L BRCA1 BRCA2 SUPV3L1 PALM3 BAMBI SCAF11 PEAK1 SPRTN TBP	1.21e-04	492	164	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	CENPE TRPM7 TRPS1 REV3L WDR76 FANCM EZH2 DNTTIP2 ORC2 ZNF800 IARS2 BRCA1 BRCA2 SUPV3L1 ETAA1 PALM3 SASS6 SCAF11 QSER1 NUDCD1 ZNF160 PSMD14 PLEKHO1 CNOT4 MYB	1.42e-04	1459	164	25	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	GTSF1 TRPM7 DTNB SRCAP CREBBP ESCO1 MAP3K1 TFR2 M1AP ZNF800 KCND2 ANKRD17 SCAF11 PEAK1 HERC1 NFAT5 CNOT4	1.47e-04	795	164	17	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_500	CACNA1D TRPS1 REV3L MYOCD ASXL2 NFAT5 CAPRIN1	1.61e-04	149	164	7	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3	SATB2 SYT3 CENPE TRPS1 REV3L BRCA2 PALM3 BAMBI PEAK1	1.70e-04	255	164	9	Facebase_RNAseq_e10.5_Maxillary Arch_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5	CACNA1C SATB2 TRPS1 CREBBP ANKRD44 BRCA2 BAMBI CACNA1G QSER1 PEAK1	2.61e-04	331	164	10	Facebase_RNAseq_e10.5_Mandibular Arch_1000_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#2	CACNA1C SATB2 CENPE TRPS1 FANCM ANKRD44 PTPRJ BRCA2 MBNL2 STARD9 NAV3 PALM3 SCAF11 CACNA1G	2.71e-04	607	164	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K2
CoexpressionAtlas	alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3	TTF2 GAS2L3 CENPE PLXND1 WDR76 EZH2 BRCA1 BRCA2 SASS6 QSER1 MYB	2.77e-04	398	164	11	GSM399397_500
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	HIPK1 USP24 GON4L PTPN23 KIAA0753 IARS2 USF3 NFATC3 UBAP2L TSSK3 CCDC191	4.89e-11	166	171	11	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GAS2L3 CFTR CCDC168 EPB41L4A CFAP65 SPRTN	6.10e-07	79	171	6	cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	GAS2L3 CFTR CCDC168 EPB41L4A CFAP65 SPRTN	6.10e-07	79	171	6	19fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SPOPL CREBBP MAP3K1 NFATC3 SCAF11 ASXL2 SPRTN NFAT5	6.35e-07	186	171	8	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTF2 GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2 SASS6	7.16e-07	189	171	8	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UAP1 TRPS1 CD164 MAP3K1 SGK3 KCNH1 SCAF11 CAPRIN1	1.02e-06	198	171	8	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	TTF2 GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2 SASS6	1.10e-06	200	171	8	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1D GRIK1 CSMD3 MAP3K1 PPARGC1A MCTP1 KCND2 PLEKHH2	1.10e-06	200	171	8	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	USP24 PLXND1 TMEM132B GZMK NAV3 TPRG1 SPRTN	1.73e-06	148	171	7	db046a02a00829910bf9d7dbda068e730aa78f00
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2 MYB	3.85e-06	167	171	7	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FANCM TFR2 ZNF544 CD226 GZMK MAPKBP1 ZNF160	6.07e-06	179	171	7	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 SATB2 MAP3K1 KIRREL1 PLEKHH2 NFAT5 TBL1X	6.53e-06	181	171	7	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARP6 RUSC2 LRFN4 KLF5 KIRREL1 CACNA1G NUDCD1	7.02e-06	183	171	7	ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM CFTR CSMD3 LRP1B PPARGC1A NAV3 MYOCD	7.27e-06	184	171	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM CFTR CSMD3 LRP1B PPARGC1A NAV3 MYOCD	7.27e-06	184	171	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM CFTR CSMD3 LRP1B PPARGC1A NAV3 MYOCD	7.27e-06	184	171	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	TRPM7 HIPK1 USP24 ZNF407 ANKRD44 HERC1 NFAT5	8.36e-06	188	171	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BTBD8 GRIK1 ADAMTS5 EEPD1 KIRREL1 PLEKHO1 MYB	8.36e-06	188	171	7	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 MAP3K1 MYOF KLF5 MYO3B KIRREL1 PLEKHH2	8.96e-06	190	171	7	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GAS2L3 CENPE FANCM EZH2 BRCA1 BRCA2 SASS6	9.92e-06	193	171	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	UAP1 DYNC2H1 TRPS1 ADAMTS5 ANKRD44 TPRG1 PLEKHH2	9.92e-06	193	171	7	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 SATB2 MAP3K1 MYOF PTPRJ KIRREL1 PLEKHH2	1.03e-05	194	171	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GAS2L3 TRPS1 SGK3 PTPRJ EEPD1 SIGLEC10 TPRG1	1.06e-05	195	171	7	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SATB2 CFTR LRFN4 HOXD13 KLF5 MLPH MYB	1.13e-05	197	171	7	e14a0e8a893c72356afc5508e3531ae0b23bfe16
ToppCell	5'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SATB2 CFTR LRFN4 HOXD13 KLF5 MLPH MYB	1.13e-05	197	171	7	19cf283537c853fa902852e7b8ac1139729a931a
ToppCell	5'-Adult-Distal_Rectal-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SATB2 CFTR LRFN4 HOXD13 KLF5 MLPH MYB	1.17e-05	198	171	7	9c0535099750698daac5d6b4d39fb19fecf4ffde
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPS1 CD164 MAP3K1 KCNH1 SCAF11 MAP4K4 CAPRIN1	1.21e-05	199	171	7	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	MGAM CENPE CCDC168 WDR76 FAM90A1 M1AP TSSK3	1.21e-05	199	171	7	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	BAZ2B DTNB TRPS1 ZNF407 PTPRJ TNRC6A HERC1	1.21e-05	199	171	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TTF2 GAS2L3 CENPE EZH2 BRCA1 BRCA2 SASS6	1.21e-05	199	171	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TTF2 GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	1.25e-05	200	171	7	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	TTF2 CENPE BAZ2B WDR76 EZH2 BRCA1 BRCA2	1.25e-05	200	171	7	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	TTF2 CENPE BAZ2B WDR76 EZH2 BRCA1 BRCA2	1.25e-05	200	171	7	dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	CSMD3 CCDC7 PPARGC1A ZNF469 TBRG1 BRCA2 DDX60L	1.25e-05	200	171	7	fe772d98c461c973dfc082e1fc50117c27ced804
ToppCell	MS-IIF-Lymphocyte-T/NK-dn_T\|IIF / Disease, condition lineage and cell class	TPO USP24 EZH2 NFATC3 RPTOR GZMK MYB	1.25e-05	200	171	7	c34fff02992cba6bcc2308019cb00b94e1227300
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TTF2 GAS2L3 CENPE BRCA1 BRCA2 SASS6	4.00e-05	163	171	6	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CENPE WDR76 EZH2 BRCA1 BRCA2 MYB	4.43e-05	166	171	6	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	4.90e-05	169	171	6	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	MGAM FLNC GAS2L3 PTPRJ MYOCD DDX60L	5.06e-05	170	171	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	control-dn_T\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GTSF1 UAP1 EZH2 GZMK TSSK3 MYB	5.06e-05	170	171	6	839f62860b4a52d06e6a8fce7632195c7310b89d
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	SATB2 TRPS1 CREM UBAP2L SPRTN MYB	5.23e-05	171	171	6	0d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	5.58e-05	173	171	6	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	5.76e-05	174	171	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GTSF1 DTNB TFR2 NFATC3 CD226 GZMK	5.76e-05	174	171	6	ccc79febfcf588d8294ffc712338be96de8a5033
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTF2 GAS2L3 CENPE EZH2 BRCA2 SIGLEC10	5.76e-05	174	171	6	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 SYT3 CENPE EZH2 BRCA1 BRCA2	5.76e-05	174	171	6	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	SATB2 UAP1 VRK2 CREBBP ZNF713 STARD9	5.94e-05	175	171	6	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 SYT3 ADAMTS5 FOXR2 SERPINA9 BMP15	6.13e-05	176	171	6	c0a084f7a8645262d61971f094689e02bf15b113
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TPO POU6F2 SATB2 LRP1B MCTP1 PLEKHH2	6.13e-05	176	171	6	0710689e66deba179b0a8038cdd56b4834984f12
ToppCell	facs-Heart-RV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 SYT3 ADAMTS5 FOXR2 SERPINA9 BMP15	6.13e-05	176	171	6	cccf9201f6e2da7524b911a5961d3b227edab222
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAS2L3 WDR76 EZH2 BRCA1 ETAA1 SPRTN	6.13e-05	176	171	6	9e719e6323597ecfc758c957256872cd4ae24d4d
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	ZNF134 PCDH12 LRP1B SLC13A4 EFCAB12 NAV3	6.33e-05	177	171	6	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPE WDR76 EZH2 GZMK SASS6 SLC29A1	6.33e-05	177	171	6	8a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TPO POU6F2 SATB2 LRP1B MCTP1 PLEKHH2	6.53e-05	178	171	6	6f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|343B / Donor, Lineage, Cell class and subclass (all cells)	EPB41L4A ORC2 PHKA2 EEPD1 GZMK ASXL2	6.53e-05	178	171	6	5289ac61637224ae70ffbc2d164d73116f10af40
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	POU6F2 SATB2 CCDC168 PLXND1 KCNH1 PLEKHH2	6.53e-05	178	171	6	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 VRK2 CD177 EPB41L4A MYOF BAMBI	6.73e-05	179	171	6	7aa4137f672dadb3be92009cde6e0ea60a15372d
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 FAM217A TMEM132B KCND2 BAMBI CACNA1G	6.94e-05	180	171	6	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TPO POU6F2 SATB2 LRP1B MCTP1 PLEKHH2	7.16e-05	181	171	6	9de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TPO POU6F2 SATB2 LRP1B MCTP1 CACNA1G	7.38e-05	182	171	6	cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	CENPE WDR76 EZH2 BRCA1 BRCA2 C18orf63	7.38e-05	182	171	6	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	UAP1 EZH2 IARS2 RPTOR GZMK ETAA1	7.38e-05	182	171	6	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 SATB2 MAP3K1 KIRREL1 PLEKHH2 TBL1X	7.61e-05	183	171	6	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CD177 GRIK1 EPB41L4A QRFPR KLF5 TBL1X	7.61e-05	183	171	6	439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	POU6F2 SATB2 PPARGC1A QRFPR KCNH1 PLEKHH2	7.84e-05	184	171	6	6475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	CENPE WDR76 EZH2 BRCA1 BRCA2 SERPINA9	8.08e-05	185	171	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	8.08e-05	185	171	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K1 ANKRD44 CD226 ANKRD17 MAP4K4 CAPRIN1	8.08e-05	185	171	6	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP3K1 ANKRD44 CD226 ANKRD17 MAP4K4 CAPRIN1	8.08e-05	185	171	6	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	FLNC ADAMTS5 EZH2 PPARGC1A FECH PLEKHH2	8.32e-05	186	171	6	6259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	8.57e-05	187	171	6	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRPM7 USP24 LRP1B PPARGC1A MYO3B	9.09e-05	189	171	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRPM7 DYNC2H1 USP24 LRP1B PPARGC1A	9.09e-05	189	171	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 PPARGC1A MYO3B ANKRD17 PLEKHH2 NFAT5	9.09e-05	189	171	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC ADAMTS5 CFAP65 MYOF KLF5 CACNA1G	9.35e-05	190	171	6	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D TRPM7 USP24 LRP1B PPARGC1A MYO3B	9.35e-05	190	171	6	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2H1 EZH2 BRCA1 BRCA2 ZBTB21 MYB	9.35e-05	190	171	6	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CENPE WDR76 EZH2 BRCA1 BRCA2 SASS6	9.63e-05	191	171	6	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C DPEP1 LARP6 ADAMTS5 FAM217A M1AP	9.63e-05	191	171	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TTF2 CENPE WDR76 EZH2 BRCA2 CD226	9.63e-05	191	171	6	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPE WDR76 EZH2 BRCA1 SERPINA9 SLC29A1	9.63e-05	191	171	6	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K1 MYOF KLF5 MYO3B KIRREL1 PLEKHH2	9.63e-05	191	171	6	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP3K1 MYOF KLF5 MYO3B KIRREL1 PLEKHH2	9.63e-05	191	171	6	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	GAS2L3 SGK3 PTPRJ EEPD1 TPRG1 DDX60L	9.91e-05	192	171	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MGAM CD177 ANKRD44 MCTP1 PTPRJ DDX60L	9.91e-05	192	171	6	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MAP3K1 MYOF PTPRJ KIRREL1 PLEKHH2	1.02e-04	193	171	6	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 MAP3K1 MYOF PTPRJ KIRREL1 PLEKHH2	1.02e-04	193	171	6	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 MAP3K1 NFATC3 MAP4K4 CAPRIN1 MYB	1.05e-04	194	171	6	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DMTF1 GTSF1 UAP1 UBAP2 ESCO1 CD226	1.05e-04	194	171	6	6be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CENPE WDR76 EZH2 BRCA1 BRCA2 GZMK	1.05e-04	194	171	6	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CPAMD8 LRP1B PTPRJ KLF5 MYO3B	1.05e-04	194	171	6	04bfc555743f7d8821439d05ae442d15e9886c59
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 CENPE WDR76 EZH2 BRCA1 BRCA2	1.05e-04	194	171	6	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CENPE WDR76 EZH2 BRCA1 BRCA2 GZMK	1.05e-04	194	171	6	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164 MAP3K1 NFATC3 MAP4K4 CAPRIN1 MYB	1.05e-04	194	171	6	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 MAP3K1 PALM3 ERVV-1 PLEKHH2 NFAT5	1.05e-04	194	171	6	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
Drug	Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; MCF7; HT_HG-U133A	CACNA1D CCDC85C SRCAP FEM1B BRCA1 BRCA2 KLF5 NFRKB PLEKHO1 CNOT4	1.59e-06	194	165	10	3454_DN
Drug	aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A	SATB2 DYNC2H1 CCDC85C PLXND1 CREM PHKA2 BRCA2 KLF5 NFAT5	1.20e-05	193	165	9	6964_DN
Drug	alpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A	SATB2 CREM FEM1B PHKA2 YEATS2 LRFN4 UBAP2L ETAA1 MAP4K4	1.36e-05	196	165	9	6970_DN
Drug	Riboflavine [83-88-5]; Down 200; 10.6uM; HL60; HG-U133A	BAZ2B CD164 USP24 PLXND1 WDR76 CREM ORC2 NFAT5 MLPH	1.36e-05	196	165	9	1767_DN
Drug	clozapine; Up 200; 10uM; MCF7; HT_HG-U133A	CACNA1D ZNF134 GON4L CREM MAP3K1 MYOF KLF5 MAPKBP1 SLC29A1	1.42e-05	197	165	9	6947_UP
Disease	alcohol consumption measurement	CACNA1C CACNA1D MGAM POU6F2 VRK2 TRPS1 WDR76 CSMD3 ACOD1 CCDC195 PTPRJ KCND2 RPTOR TNRC6A SCAF11 ASXL2 PEAK1 AGBL2 NFAT5 CNOT4	1.83e-05	1242	163	20	EFO_0007878
Disease	ductal carcinoma in situ (biomarker_via_orthology)	BRCA1 BRCA2	3.03e-05	2	163	2	DOID:0060074 (biomarker_via_orthology)
Disease	Hereditary site-specific ovarian cancer syndrome	BRCA1 BRCA2	3.03e-05	2	163	2	C4749652
Disease	Mobius Syndrome	PLXND1 REV3L	3.03e-05	2	163	2	C0221060
Disease	Mobius II syndrome	PLXND1 REV3L	3.03e-05	2	163	2	C0853240
Disease	hematocrit	SLAIN2 CACNA1C DPEP1 UBAP2 TRPS1 EPB41L4A TFR2 FEM1B PPARGC1A PTPRJ KCNH1 PSORS1C1 ANKRD17 ASXL2 SPRTN NFAT5 MYB	4.77e-05	1011	163	17	EFO_0004348
Disease	smoking status measurement	CACNA1C CACNA1D VRK2 SYT3 GATB ZNF407 GRIK1 REV3L TMEM132B CCDC195 MCTP1 KCND2 UBAP2L TNRC6A QSER1 HERC1 AGBL2 NFAT5	7.92e-05	1160	163	18	EFO_0006527
Disease	Colorectal Neoplasms	FLNC CPAMD8 SATB2 TRPM7 CFTR CABYR CD226 KLF5	1.62e-04	277	163	8	C0009404
Disease	hair colour measurement	DPEP1 ATXN7L1 TRPS1 TRMO REV3L MAP3K1 ZNF469 KCNH1 TPRG1 ASXL2 QSER1 MYB	1.69e-04	615	163	12	EFO_0007822
Disease	Hereditary breast ovarian cancer syndrome	BRCA1 BRCA2	1.81e-04	4	163	2	cv:C0677776
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	1.81e-04	4	163	2	DOID:0060173 (implicated_via_orthology)
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	DYNC2H1 MAP3K1 BRCA2 KCNH1	1.98e-04	52	163	4	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	Pancreatic Neoplasm	BRCA1 BRCA2 KLF5 ETAA1 SLC29A1	2.39e-04	100	163	5	C0030297
Disease	Malignant neoplasm of pancreas	BRCA1 BRCA2 KLF5 ETAA1 SLC29A1	2.62e-04	102	163	5	C0346647
Disease	hereditary breast ovarian cancer syndrome (is_implicated_in)	BRCA1 BRCA2	3.00e-04	5	163	2	DOID:5683 (is_implicated_in)
Disease	Fanconi Anemia	FANCM BRCA1 BRCA2	3.48e-04	25	163	3	C0015625
Disease	renal overload-type gout	SPATA31C2 SPATA31C1	4.48e-04	6	163	2	EFO_0021525
Disease	Adult only	BRCA1 BRCA2	4.48e-04	6	163	2	C3842001
Disease	sleep quality	CACNA1C TRPS1 EPB41L4A LRP1B NUDCD1	5.12e-04	118	163	5	EFO_0005272
Disease	MYELODYSPLASTIC SYNDROME	FANCM EZH2 BRCA1 BRCA2	5.25e-04	67	163	4	C3463824
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	CACNA1D VRK2 ZNF407 GRIK1 REV3L TMEM132B CCDC195 MCTP1 KCND2 UBAP2L TNRC6A HERC1 NFAT5	5.32e-04	801	163	13	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Miller Dieker syndrome	FANCM BRCA1 BRCA2	5.44e-04	29	163	3	C0265219
Disease	Colorectal Carcinoma	DPEP1 FLNC CPAMD8 SATB2 TRPM7 CFTR CSMD3 CABYR CD226 KLF5 ETAA1 SLC29A1	5.55e-04	702	163	12	C0009402
Disease	colorectal cancer (is_implicated_in)	EZH2 LRP1B BRCA1 PTPRJ BAMBI	5.74e-04	121	163	5	DOID:9256 (is_implicated_in)
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	DYNC2H1 KIAA0753	6.25e-04	7	163	2	DOID:0050592 (is_implicated_in)
Disease	Manic Disorder	CACNA1C CACNA1D STARD9 PLEKHO1	6.54e-04	71	163	4	C0024713
Disease	stomach cancer (is_implicated_in)	EZH2 LRP1B MAP3K1 BRCA1	6.89e-04	72	163	4	DOID:10534 (is_implicated_in)
Disease	reticulocyte count	UBAP2 DTNB TRPS1 MAP3K1 TFR2 USP10 ZNF800 ZNF469 PTPRJ CD226 EEPD1 NFRKB PALM3 ASXL2 HERC1	7.15e-04	1045	163	15	EFO_0007986
Disease	testosterone measurement	CACNA1D SATB2 VRK2 SPEM3 CENPE TRPS1 CCDC85C SRCAP WDR76 CSMD3 KIAA0753 ZNF800 PTPRJ C18orf63 PALM3 MYOCD TBL1X	7.22e-04	1275	163	17	EFO_0004908
Disease	mood instability measurement	VRK2 LRP1B TNRC6A AGBL2 FOXK1	7.41e-04	128	163	5	EFO_0008475
Disease	cutaneous squamous cell carcinoma	TRPS1 BRCA2 TPRG1	7.99e-04	33	163	3	EFO_1001927
Disease	Nephroblastoma	POU6F2 BRCA2	8.31e-04	8	163	2	cv:C0027708
Disease	eosinophil cationic protein measurement	SPATA31C2 SPATA31C1	8.31e-04	8	163	2	EFO_0010913
Disease	Hereditary Wilms tumor	POU6F2 BRCA2	8.31e-04	8	163	2	cv:C0677779
Disease	Kidney Wilms tumor	POU6F2 BRCA2	8.31e-04	8	163	2	cv:CN305775
Disease	Manic	CACNA1C CACNA1D STARD9 PLEKHO1	9.32e-04	78	163	4	C0338831
Disease	Depression, Bipolar	CACNA1C CACNA1D STARD9 PLEKHO1	9.77e-04	79	163	4	C0005587
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1D DTNB	1.03e-03	36	163	3	DOID:11723 (implicated_via_orthology)
Disease	longitudinal alcohol consumption measurement	SPATA31C2 SPATA31C1	1.06e-03	9	163	2	EFO_0007645
Disease	Pancreatic carcinoma, familial	BRCA1 BRCA2	1.06e-03	9	163	2	C2931038
Disease	colorectal carcinoma (is_marker_for)	EZH2 BRCA1 BRCA2	1.12e-03	37	163	3	DOID:0080199 (is_marker_for)
Disease	cataract	CPAMD8 LRP1B ZNF800 BAMBI NFAT5	1.14e-03	141	163	5	MONDO_0005129
Disease	venous thromboembolism, factor VII measurement	TTF2 PTPRJ ZNF160	1.21e-03	38	163	3	EFO_0004286, EFO_0004619
Disease	Fanconi anemia (is_implicated_in)	BRCA1 BRCA2	1.33e-03	10	163	2	DOID:13636 (is_implicated_in)
Disease	venous thromboembolism, von Willebrand factor measurement	TTF2 PTPRJ ZNF160	1.62e-03	42	163	3	EFO_0004286, EFO_0004629
Disease	colorectal cancer (is_marker_for)	EZH2 BRCA1 BRCA2 BAMBI MAP4K4	1.84e-03	157	163	5	DOID:9256 (is_marker_for)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	MAP3K1 BRCA1 BRCA2	1.98e-03	45	163	3	DOID:3748 (is_implicated_in)
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C VRK2 PTPRJ TNRC6A	2.09e-03	97	163	4	EFO_0007878, EFO_0009458
Disease	dimethylglycine measurement	CSMD3 ANKRD44 CACNA1G	2.11e-03	46	163	3	EFO_0010476
Disease	uric acid measurement	DPEP1 TRPM7 DYNC2H1 EZH2 DDX1 MYOF PSORS1C1 ASXL2 NFAT5 FOXK1	2.17e-03	610	163	10	EFO_0004761
Disease	intraocular pressure measurement	TTF2 POU6F2 DYNC2H1 MYOF ZNF469 PTPRJ KLF5 BAMBI MLPH	2.17e-03	509	163	9	EFO_0004695
Disease	Benign tumor of pancreas	BRCA1 BRCA2	2.27e-03	13	163	2	C0347284
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C2 SPATA31C1	2.27e-03	13	163	2	EFO_0005939, EFO_0007018
Disease	Skin Abnormalities	ZNF469 SUPV3L1	2.27e-03	13	163	2	C0037268
Disease	Adenoid Cystic Carcinoma	SRCAP CREBBP BRCA1 MYB	2.33e-03	100	163	4	C0010606
Disease	lung adenocarcinoma (is_implicated_in)	LRP1B PTPRJ MAP4K4	2.53e-03	49	163	3	DOID:3910 (is_implicated_in)
Disease	nephroblastoma (is_implicated_in)	POU6F2 BRCA2	2.64e-03	14	163	2	DOID:2154 (is_implicated_in)
Disease	Chromosome Breakage	EZH2 BRCA1	2.64e-03	14	163	2	C0376628
Disease	Chromosome Breaks	EZH2 BRCA1	2.64e-03	14	163	2	C0333704
Disease	Hereditary Breast and Ovarian Cancer Syndrome	BRCA1 BRCA2	2.64e-03	14	163	2	C0677776
Disease	smoking behavior	CACNA1D POU6F2 ZNF407 REV3L TMEM132B MCTP1 NAV3	2.97e-03	341	163	7	EFO_0004318
Disease	Lymphoma, Follicular, Grade 2	EZH2 CREBBP	3.04e-03	15	163	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	EZH2 CREBBP	3.04e-03	15	163	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	EZH2 CREBBP	3.04e-03	15	163	2	C1956130
Disease	Autosomal recessive primary microcephaly	CENPE SASS6	3.04e-03	15	163	2	cv:C3711387
Disease	Lymphoma, Large-Cell, Follicular	EZH2 CREBBP	3.04e-03	15	163	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	EZH2 CREBBP	3.04e-03	15	163	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	EZH2 CREBBP	3.04e-03	15	163	2	C0079758
Disease	response to olanzapine	CACNA1C SPOPL	3.04e-03	15	163	2	GO_0097333
Disease	unipolar depression, cognitive function measurement	ADAMTS5 SGK3	3.04e-03	15	163	2	EFO_0003761, EFO_0008354
Disease	Huntington's disease (is_marker_for)	CREBBP PPARGC1A TBP	3.17e-03	53	163	3	DOID:12858 (is_marker_for)
Disease	waist-hip ratio	CPAMD8 VRK2 DYNC2H1 ATXN7L1 CFTR ZNF407 PLXND1 CFAP65 YEATS2 MYO3B TNRC6A ETAA1 NAV3 MAPKBP1 NFAT5	3.38e-03	1226	163	15	EFO_0004343
Disease	amygdala volume change measurement	SPATA31C2 SPATA31C1	3.46e-03	16	163	2	EFO_0021490
Disease	nervousness	PTPRJ AGBL2	3.46e-03	16	163	2	NCIT_C74532
Disease	Antibody Deficiency Syndrome	CACNA1C C5	3.91e-03	17	163	2	C0003257
Disease	Limb Deformities, Congenital	CACNA1C HOXD13	3.91e-03	17	163	2	C0206762
Disease	diastolic blood pressure, systolic blood pressure	CACNA1C CACNA1D DPEP1 DYNC2H1 TRPS1 PPARGC1A ZNF800 PSORS1C1 MYOCD NFAT5	4.22e-03	670	163	10	EFO_0006335, EFO_0006336
Disease	level of Sphingomyelin (d34:1) in blood serum	USP24 ANKRD17	4.38e-03	18	163	2	OBA_2045175
Disease	Bone marrow hypocellularity	FANCM BRCA2	4.38e-03	18	163	2	C1855710
Disease	age at onset, Parkinson disease	TRPS1 QSER1	4.38e-03	18	163	2	EFO_0004847, MONDO_0005180
Disease	peripheral arterial disease, traffic air pollution measurement	SPOPL TRPS1 CCDC7 MCTP1 CNOT4	4.55e-03	194	163	5	EFO_0004265, EFO_0007908
Disease	Pancreatic carcinoma	BRCA1 BRCA2	4.88e-03	19	163	2	C0235974
Disease	unipolar depression, response to bupropion, mood disorder	CCDC195 NAV3	4.88e-03	19	163	2	EFO_0003761, EFO_0004247, EFO_0006326
Disease	pursuit maintenance gain measurement	CACNA1D SPATA31C2 SPATA31C1 DDX60L	4.90e-03	123	163	4	EFO_0008433
Disease	neuroimaging measurement, brain volume measurement	TRPS1 ESCO1 MAP3K1 PPARGC1A NAV3 NFAT5	5.26e-03	286	163	6	EFO_0004346, EFO_0006930
Disease	Adenocarcinoma of prostate	BRCA1 BRCA2	5.40e-03	20	163	2	C0007112
Disease	Lymphoma, Follicular	EZH2 CREBBP	5.40e-03	20	163	2	C0024301
Disease	visceral adipose tissue measurement	CACNA1C TRPS1 YEATS2 RPTOR MYO3B TNRC6A AGBL2 NFAT5	5.44e-03	481	163	8	EFO_0004765

Protein segments in the cluster

Peptide	Gene	Start	Entry
CPTQGTRKNHESNSS	FAM223B	56	A6NKX1
NTPLQDKGNSTHSRN	CFTR	886	P13569
GAEVSPSATTNQNHK	BTN3A3	561	O00478
PSATTNQNHKLQART	BTN3A3	566	O00478
NQPHGTNSSSVAIAI	CSMD3	3621	Q7Z407
NQLPSGHSKVVTLSQ	CCDC7	1336	Q96M83
TPKVNSVTSHGSNKV	ADAMTS5	856	Q9UNA0
QNSGKHSLGSVQSTA	BAZ2B	1501	Q9UIF8
GLQCKQTHPTNSTSG	GRIK1	876	P39086
QSPTVVLGAHSLSKN	GZMK	76	P49863
VKTQHPDNSAGKISS	FCRL4	496	Q96PJ5
QASHLPGQQIATSLS	CREBBP	2326	Q92793
GESSVAQQPLHTAQK	GATB	41	O75879
KSVPLQVSLANSAHQ	ERVV-2	81	B6SEH9
VNQTSVHVDLGSQPK	CABYR	236	O75952
STVGAQNSQKTTIHS	CD177	266	Q8N6Q3
QNSQKTTIHSAPPGV	CD177	271	Q8N6Q3
TAPHKNSASVQNSSV	ANKRD17	2186	O75179
GTSKPLHSSGINVNA	CAPRIN1	496	Q14444
SGVPNSNTNSSVQHV	DMTF1	426	Q9Y222
VKRSSGLQQTHPNSF	EFCAB12	491	Q6NXP0
PAHTFTNISTKNPQG	EEPD1	471	Q7L9B9
HNSNNGVSPLSAKLE	ATXN7L1	701	Q9ULK2
QSHPATQQQLGKTLQ	ASXL2	1011	Q76L83
IVNKTFSPAQRHGNS	QRFPR	351	Q96P65
KPLHNQSSVISGQAQ	QSER1	311	Q2KHR3
SASISQKNHLPQDSQ	PTPN23	1471	Q9H3S7
NTLKTTHVVNLGSNQ	NUDCD1	426	Q96RS6
QLLQSASTGAQHKPS	PALM3	96	A6NDB9
PHTGQLFVNVTNASS	PCDH12	651	Q9NPG4
TNHSSPEAQSKQTGR	MAP4K4	576	O95819
GSPNITSVSHNSVKV	PTPRJ	821	Q12913
NGSDIKVVHNTAVPN	LRP1B	3076	Q9NZR2
HGSSQKIINTAGTSN	MCTP1	236	Q6DN14
TTGKGPSTHTQIDQQ	M1AP	6	Q8TC57
IQTVPASHLQQGTAS	NFRKB	1261	Q6P4R8
LSADKNTTQHPNVTT	CD164	21	Q04900
NSTLTKVLNSTGNHT	ERVFC1-1	361	P60608
PQAASKTHGLLQAVS	FAM90A1	241	Q86YD7
SKTLPATQGQANSSH	HIPK1	46	Q86Z02
SPASNIVTEHKNNLA	GTSF1	131	Q8WW33
SQSHISLGNIPVQSK	CFAP65	1441	Q6ZU64
SNVTVKHNGVPSQTS	MGAM	911	O43451
PSNVTVKHNGVPSQT	MGAM	1806	O43451
NVGIHVPTVVNSNKS	FANCM	1956	Q8IYD8
KVKQQQHSPESSSGS	HERC1	126	Q15751
VTASSSKHSGPENNQ	BMP15	276	O95972
SSKPSIRQHLSGNQF	CCDC85C	401	A6NKD9
SGASGEILQNTKPHQ	DDX60L	551	Q5H9U9
KHSPNQATNQLSIIA	CCDC195	186	A0A1B0GUA6
GANVNHTTVTNSTPL	FEM1B	111	Q9UK73
IVKSQHSGNAQVTQT	DDX1	266	Q92499
KSVPLQVSLANSAHQ	ERVV-1	81	B6SEH8
GPNAKSVQREQSLHS	EZH2	266	Q15910
NVAANHPNASTVGLV	PLXND1	181	Q9Y4D7
APITHGNVKTNANHS	PEAK1	36	Q9H792
NLKTQQSQHPTDALS	TPO	106	P07202
TQSNHSGIATSQKKP	NAV3	231	Q8IVL0
QKQSNSKAVPQGSAH	FAM205A	976	Q6ZU69
QGSAHSVSKISQPSG	FAM205A	986	Q6ZU69
CPTQGTRKNHESNSS	FAM223A	56	Q8IWN6
NHVTARVLNPSGAKT	FLNC	1286	Q14315
KTFRIPNANVSGSHQ	KCND2	536	Q9NZV8
QAASTSGVPDHAKLQ	KCNH1	801	O95259
LTPHSKQQQGSSLRQ	LRRC75B	121	Q2VPJ9
AATNKLSPSGHQNLF	LARP6	356	Q9BRS8
SQPAVATSFQKNSHL	MYB	206	P10242
HSAPVNAVDNSGKTA	ANKRD44	861	Q8N8A2
RPKSSQIGAVVSHQS	PNPO	161	Q9NVS9
EKQLTSNTVQQHPST	NFAT5	121	O94916
ASQPSHQSDAGKQGL	MYOCD	211	Q8IZQ8
STPAGHVTNQCKVNQ	PLEKHH2	1276	Q8IVE3
QSKHLNPGSISVQTS	ETAA1	691	Q9NY74
SQSQHLQAKPTTLSL	PPARGC1A	246	Q9UBK2
FGKVNNIPSQSTRHS	BRCA1	1231	P38398
LGQSTNPSVIQSHLK	DYNC2H1	1441	Q8NCM8
TTQRPLHINKAGSSQ	CACNA1C	1771	Q13936
QAKQARNHSGTTIPT	BAMBI	81	Q13145
KPQSINTVSAHLQSS	BRCA2	1061	P51587
LPKAQSGSVLSVHSQ	CACNA1G	2071	O43497
SAQTVAKSQHSTKGP	GAS2L3	631	Q86XJ1
HTIGQTSNSLTNQEP	BTBD8	86	Q5XKL5
NLQHKDSSVPNTGTA	C5	1231	P01031
LSGQQPAHTTQQRSK	CPAMD8	496	Q8IZJ3
SLQNVSLSAPGNKQH	CCDC191	506	Q8NCU4
SHGVGLQQNALKSSP	HOXD13	141	P35453
ISQQLGNKTPAEVSH	GON4L	2181	Q3T8J9
EQKQAAQATGSPHTS	DTNB	521	O60941
AVTQNGKHAVPTNSL	FOXK1	621	P85037
FKAQRGSLPNSATHQ	AGBL2	31	Q5U5Z8
QSPFTNHAAAAGRKT	C17orf80	441	Q9BSJ5
KSNGTSAVFNPSVLH	MBNL2	286	Q5VZF2
TSAQLQQHAAFIPTG	MBNL2	306	Q5VZF2
TASPFSGLQKAQSVH	MAPKBP1	1186	O60336
SGLQKAQSVHSLVPQ	MAPKBP1	1191	O60336
NAATQTKPLHIGNAA	ACOD1	201	A6NK06
SEQSPLQKQGIHSPS	FOXR2	136	Q6PJQ5
NKVGSTNVSTLVNVH	KIRREL1	291	Q96J84
APQQHSILSNQTSKS	ESCO1	551	Q5FWF5
QPQTHFTQTILKSTS	CCDC168	1601	Q8NDH2
TTETAQHAQGAKPQV	FECH	46	P22830
SNSHIVSEPGKNVTL	CD226	136	Q15762
EPNLSVHSQKSTQNS	FAM217A	66	Q8IXS0
EHNSSSLKQNPAAAV	C4orf54	561	D6RIA3
SKSAHVQTQTGQNSI	CREM	21	Q03060
ANLTTLAGTHTNIPK	DPEP1	56	P16444
EKPQTSTNNLAGKHT	EPB41L4A	656	Q9HCS5
PSITNPIKTANQHQG	SLC13A4	216	Q9UKG4
LQGIPSSSHVSNNMS	SCAF11	1301	Q99590
SAKNTSHPGSGTKVQ	SASS6	546	Q6UVJ0
SSQKLHSTSQNINLG	SGK3	136	Q96BR1
HNHNSIGKQVPTSTN	CACNA1D	1741	Q01668
NKNPHVTSRATQLTT	CENPE	2366	Q02224
QHTNLSSQSNITPKF	C18orf63	421	Q68DL7
VGTAAHQTNRQEKSP	MLPH	431	Q9BV36
QNPVTGLLSASHEQK	PHKA2	26	P46019
QTTSNLGHLNKPSIQ	PSMD14	176	O00487
VQTKGRPHSQCLNSS	MAP3K1	956	Q13233
ITINVPQSSKGHSAS	ORC2	131	Q13416
AKLGNSSVSPNVGHL	RUSC2	1021	Q8N2Y8
GGLPSAQSHQQVTSL	SYT3	206	Q9BQG1
SLQGHPTDLQTSNVK	SLAIN2	391	Q9P270
AFPVSNTHVKTSNLA	SPATA31C2	606	B4DYI2
NGSSQKTFHSQLLRP	TMEM132B	986	Q14DG7
QLHQPSQTSVGQAAS	POU6F2	411	P78424
LASLGKTNEQSPHSQ	SATB2	261	Q9UPW6
LNTQTQPKAHTTGDR	ST6GALNAC1	86	Q9NSC7
LVRSVSGASNHQPNS	IARS2	41	Q9NSE4
SKQNKQVHASHTPGT	STARD9	2066	Q9P2P6
VQNSTSASGPKQDHV	STARD9	2821	Q9P2P6
TVQPNGKQASHVSCT	SUPV3L1	261	Q8IYB8
SQPHSKSRVQQTTVS	KIAA0753	526	Q2KHM9
QAFPVSNTHVKTSNL	SPATA31C1	611	P0DKV0
TQGANHTPVISAHQT	SRCAP	2406	Q6ZRS2
TLAHSKQPGNTAPNL	PLEKHO1	96	Q53GL0
LTQSAPASPTNKGVH	RPTOR	856	Q8N122
SNSQPTNESHSIKAI	SLC29A1	271	Q99808
SNPSIAQARINSHVK	SERPINA9	166	Q86WD7
TSSHSLQQGQQPTSL	CNOT4	556	O95628
TTTSAGVSHQNPSKN	TBL1X	176	O60907
GVSHQNPSKNREATV	TBL1X	181	O60907
SQRHSTPQNKNAVSV	DNTTIP2	336	Q5QJE6
AQGSLTKSHSAQQPV	TRPS1	1006	Q9UHF7
TKSHSAQQPVLVSQT	TRPS1	1011	Q9UHF7
NQHTPNTVSQSDSKT	TRMO	181	Q9BU70
ASAKQHGVNLSTPTP	UBAP2	936	Q5T6F2
TQHGIVKNPSPASSS	ZBTB21	596	Q9ULJ3
SNLATHQVIHTGTKP	ZNF160	466	Q9HCG1
TSSKQHGVNVSVNAS	UBAP2L	936	Q14157
LGNPSSTAQHVFKVS	REV3L	91	O60673
GITQDSHPQKNTGLT	SPEM3	751	A0A1B0GUW6
SHPQKNTGLTQEAGI	SPEM3	756	A0A1B0GUW6
NGHTPSSNGALKTQD	REV1	226	Q9UBZ9
GQAPQLFHSQTLTTA	TBP	116	P20226
QQQKGVSFPTHLSIS	TSSK3	221	Q96PN8
SHPVSQTQHASGQKL	RHBDD2	266	Q6NTF9
DSVNISGHTNTNTLK	SPOPL	166	Q6IQ16
QKSHSQRALGTQTPA	PSORS1C1	6	Q9UIG5
PAIQNAHKNSTGSGR	TPRG1	221	Q6ZUI0
SSVLSPSFQLQSHKN	NFATC3	71	Q12968
TQTSQLSLQPKHHGT	USF3	1531	Q68DE3
SQNGKDNPTTARHAL	UAP1	411	Q16222
QNGSSKNSHLVSPAV	SPRTN	306	Q9H040
NHASVNASPKTALTG	ZNF469	1986	Q96JG9
NAFSGKSTLIQHQVT	ZNF251	601	Q9BRH9
NSSSAVHTESNKLQP	WDR76	111	Q9H967
SKQQHQPSASSILES	USP24	1146	Q9UPU5
GNLFSHSVSLNEQKP	ZNF544	276	Q6NX49
LVNGHANSAVPNSVS	USP10	176	Q14694
PSITHSPQNELKGTN	ZNF800	421	Q2TB10
PLNSDTQGNSIKHNS	ZNF713	206	Q8N859
ESTKNTLQAAHGNSV	ZNF407	396	Q9C0G0
ETTKGAPVATNHQSR	SIGLEC10	66	Q96LC7
SVLKQVDSPNHSGQT	TFR2	531	Q9UP52
QHLKSPSQGSPIQSS	TBRG1	396	Q3YBR2
VNTSLDQNSSKHGAI	TNRC6A	1546	Q8NDV7
KHGVVNTLSSSLPQG	TRPM7	1291	Q96QT4
STKGQSINVHTPNSQ	VRK2	326	Q86Y07
SINVHTPNSQKVDSQ	VRK2	331	Q86Y07
HVNTSKAGLPAQTAL	ZNF134	36	P52741
KIHSSQSSPQQAVLT	YEATS2	1036	Q9ULM3
SQVPQQSHFTKTTTG	TTF2	471	Q9UNY4
AGLNTHTSAVPQTAV	KLF5	261	Q13887
LKLSHVQSQTNGGPS	LRFN4	551	Q6PJG9
SSNSPAVTEKNGHSQ	MYO3B	1181	Q8WXR4
AVTEKNGHSQAQSSP	MYO3B	1186	Q8WXR4
TLHSTFQPNISQGKL	MYOF	1746	Q9NZM1