Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkinase activity

NEK6 ATR BMP2K WEE1 LRRK2 PI4K2A PTK6 CCNE1 ULK3 JAK2 ITPKC EGFR MTOR PKM EPHA3 EPHA5

1.52e-0576412116GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

NEK6 ATR BMP2K WEE1 LRRK2 PI4K2A PTK6 ULK3 JAK2 ITPKC EGFR MTOR PKM EPHA3 EPHA5

2.55e-0570912115GO:0016773
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

WEE1 PTK6 JAK2 EGFR PKM EPHA3 EPHA5

2.92e-051451217GO:0004713
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

NEK6 ATR BMP2K WEE1 LRRK2 PI4K2A POLR3A PTK6 CCNE1 ULK3 JAK2 ITPKC EGFR MTOR PKM EPHA3 EPHA5

5.07e-0593812117GO:0016772
GeneOntologyMolecularFunctionacetylcholine binding

ACHE CHRNA7 CHRFAM7A

5.94e-05131213GO:0042166
GeneOntologyMolecularFunctionprotein kinase activity

NEK6 ATR BMP2K WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR MTOR PKM EPHA3 EPHA5

7.20e-0560012113GO:0004672
GeneOntologyMolecularFunctionadenylate cyclase binding

CHRNA7 ADCYAP1R1 CHRFAM7A

1.15e-04161213GO:0008179
GeneOntologyMolecularFunctionnon-membrane spanning protein tyrosine kinase activity

WEE1 PTK6 JAK2 PKM

1.72e-04461214GO:0004715
GeneOntologyMolecularFunctionamyloid-beta binding

ACHE APBB3 CHRNA7 CHRFAM7A VBP1

3.92e-041021215GO:0001540
GeneOntologyMolecularFunctionGPI-linked ephrin receptor activity

EPHA3 EPHA5

7.50e-0471212GO:0005004
GeneOntologyMolecularFunctionmagnesium ion binding

NEK6 WEE1 LRRK2 PI4K2A ATP9B POLR3A PKM

7.77e-042471217GO:0000287
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BRIP1 ATRX CHD8 DDX1 CHD6

1.06e-031271215GO:0008094
GeneOntologyBiologicalProcesspeptidyl-serine modification

NEK6 ATR LRRK2 CHRNA7 ULK3 POGLUT1 EGFR MTOR DMD CHRFAM7A

1.89e-0531912110GO:0018209
GeneOntologyBiologicalProcessregulation of DNA replication

ATR ATRX JADE3 WEE1 JADE1 PTK6 EGFR

2.59e-051471217GO:0006275
GeneOntologyBiologicalProcesspositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

3.41e-0521212GO:0001988
GeneOntologyBiologicalProcesspancreas regeneration

REG1A REG1B

3.41e-0521212GO:1990798
GeneOntologyBiologicalProcessneuron development

HEXA WEE1 ACHE LRRK2 CASP6 REG1A REG1B NIBAN2 ADGRV1 TTC3 CHRNA7 PTK6 SEMA4C JAK2 EGFR MTOR RORB DMD CHRFAM7A SLC23A2 EPHA3 EPHA5

3.83e-05146312122GO:0048666
GeneOntologyBiologicalProcessneuron projection development

WEE1 ACHE LRRK2 CASP6 REG1A REG1B NIBAN2 ADGRV1 TTC3 CHRNA7 PTK6 SEMA4C JAK2 EGFR MTOR DMD CHRFAM7A SLC23A2 EPHA3 EPHA5

5.64e-05128512120GO:0031175
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

METTL3 BMP2K DTX1 LRRK2 NIBAN2 POGLUT1

5.73e-051141216GO:0008593
GeneOntologyBiologicalProcessprotein autophosphorylation

NEK6 ATR LRRK2 PTK6 ULK3 JAK2 EGFR MTOR

6.07e-052281218GO:0046777
GeneOntologyBiologicalProcessneuron projection morphogenesis

WEE1 ACHE LRRK2 REG1A REG1B NIBAN2 TTC3 CHRNA7 SEMA4C EGFR DMD CHRFAM7A SLC23A2 EPHA3 EPHA5

7.19e-0580212115GO:0048812
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

NEK6 ATR LRRK2 CHRNA7 ULK3 EGFR MTOR DMD CHRFAM7A

8.38e-053071219GO:0018105
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

WEE1 ACHE LRRK2 REG1A REG1B NIBAN2 TTC3 CHRNA7 SEMA4C EGFR DMD CHRFAM7A SLC23A2 EPHA3 EPHA5

9.08e-0581912115GO:0120039
GeneOntologyBiologicalProcessDNA replication

CHAF1B ATR ATRX JADE3 WEE1 JADE1 PTK6 CCNE1 EGFR

9.48e-053121219GO:0006260
GeneOntologyBiologicalProcesscell projection morphogenesis

WEE1 ACHE LRRK2 REG1A REG1B NIBAN2 TTC3 CHRNA7 SEMA4C EGFR DMD CHRFAM7A SLC23A2 EPHA3 EPHA5

9.98e-0582612115GO:0048858
GeneOntologyBiologicalProcesspositive regulation of acinar cell proliferation

REG1A REG1B

1.02e-0431212GO:1904699
GeneOntologyBiologicalProcessbaroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

1.02e-0431212GO:0001982
GeneOntologyBiologicalProcesssynaptic transmission, cholinergic

ACHE CHRNA7 DMD CHRFAM7A

1.28e-04441214GO:0007271
GeneOntologyBiologicalProcessregulation of amyloid fibril formation

CHRNA7 CHRFAM7A VBP1

1.78e-04191213GO:1905906
GeneOntologyBiologicalProcessgeneration of ovulation cycle rhythm

CHRNA7 CHRFAM7A

2.03e-0441212GO:0060112
GeneOntologyBiologicalProcessNotch signaling pathway

METTL3 BMP2K IFT172 DTX1 LRRK2 NIBAN2 POGLUT1

2.43e-042101217GO:0007219
GeneOntologyBiologicalProcesssensory processing

CHRNA7 CHRFAM7A

3.37e-0451212GO:0050893
GeneOntologyBiologicalProcessregulation of acinar cell proliferation

REG1A REG1B

3.37e-0451212GO:1904697
GeneOntologyBiologicalProcesspositive regulation of cytoplasmic translational initiation

METTL3 MTOR

3.37e-0451212GO:1904690
GeneOntologyBiologicalProcessacinar cell proliferation

REG1A REG1B

3.37e-0451212GO:1990863
GeneOntologyBiologicalProcesspositive regulation of DNA replication

ATRX WEE1 PTK6 EGFR

3.74e-04581214GO:0045740
GeneOntologyCellularComponentneuronal cell body

DRP2 ACHE LRRK2 PI4K2A CYGB CASP6 REG1A REG1B CNKSR2 CHRNA7 TRPM5 CLCN2 MTOR IGSF9B DMD CHRFAM7A CD200 EPHA5

1.49e-0683512118GO:0043025
GeneOntologyCellularComponentcell body

DRP2 ACHE LRRK2 PI4K2A CYGB CASP6 REG1A REG1B CNKSR2 CHRNA7 TRPM5 CLCN2 MTOR IGSF9B DMD GNB2 CHRFAM7A CD200 EPHA5

1.61e-0692912119GO:0044297
GeneOntologyCellularComponentsomatodendritic compartment

DRP2 ACHE LRRK2 PI4K2A CYGB CASP6 REG1A REG1B CNKSR2 CHRNA7 TRPM5 CLCN2 MTOR IGSF9B DMD CHRFAM7A CD200 EPHA3 EPHA5

8.03e-05122812119GO:0036477
GeneOntologyCellularComponentspine apparatus membrane

CHRNA7 CHRFAM7A

9.93e-0531212GO:0098897
GeneOntologyCellularComponentneuron projection membrane

REG1A REG1B ADGRV1 CHRNA7 CHRFAM7A

1.14e-04821215GO:0032589
GeneOntologyCellularComponentsyntrophin complex

SNTG1 DMD

1.98e-0441212GO:0016013
GeneOntologyCellularComponentdystrophin-associated glycoprotein complex

SNTG1 DMD UTRN

2.01e-04201213GO:0016010
GeneOntologyCellularComponentcell projection membrane

PKD1L1 REG1A REG1B ADGRV1 CHRNA7 EGFR SNTG1 DMD CHRFAM7A UTRN

2.07e-0443112110GO:0031253
GeneOntologyCellularComponentleading edge membrane

REG1A REG1B ADGRV1 CHRNA7 EGFR SNTG1 CHRFAM7A

2.24e-042101217GO:0031256
GeneOntologyCellularComponentglycoprotein complex

SNTG1 DMD UTRN

3.96e-04251213GO:0090665
GeneOntologyCellularComponentdendrite

DRP2 ACHE LRRK2 PI4K2A REG1A REG1B CHRNA7 TRPM5 CLCN2 MTOR IGSF9B CHRFAM7A EPHA3 EPHA5

4.46e-0485812114GO:0030425
GeneOntologyCellularComponentdendritic tree

DRP2 ACHE LRRK2 PI4K2A REG1A REG1B CHRNA7 TRPM5 CLCN2 MTOR IGSF9B CHRFAM7A EPHA3 EPHA5

4.57e-0486012114GO:0097447
GeneOntologyCellularComponentmultivesicular body, internal vesicle

LRRK2 EGFR

4.91e-0461212GO:0097487
GeneOntologyCellularComponentpostsynaptic membrane

ACHE CNKSR2 CHRNA7 SEMA4C LRFN2 IGSF9B DMD CHRFAM7A UTRN

5.89e-044051219GO:0045211
GeneOntologyCellularComponentpostsynapse

DRP2 ATR ACHE LRRK2 CNKSR2 CHRNA7 SEMA4C JAK2 LRFN2 MTOR IGSF9B DMD CHRFAM7A UTRN CD200

7.99e-04101812115GO:0098794
GeneOntologyCellularComponentspine apparatus

CHRNA7 CHRFAM7A

1.16e-0391212GO:0097444
GeneOntologyCellularComponentmembrane raft

LRRK2 PI4K2A CHRNA7 ADCYAP1R1 JAK2 EGFR DMD CHRFAM7A

1.23e-033621218GO:0045121
GeneOntologyCellularComponentmembrane microdomain

LRRK2 PI4K2A CHRNA7 ADCYAP1R1 JAK2 EGFR DMD CHRFAM7A

1.28e-033641218GO:0098857
GeneOntologyCellularComponenttransport vesicle membrane

ATR LRRK2 PI4K2A SEMA4C AP1B1 CNIH1 DMD

1.60e-032931217GO:0030658
GeneOntologyCellularComponentmonoatomic ion channel complex

PKD1L1 KCNK16 CHRNA7 TRPM5 CLCN2 KCNG1 KCNG4 CHRFAM7A

1.62e-033781218GO:0034702
GeneOntologyCellularComponentplasma membrane raft

LRRK2 CHRNA7 ADCYAP1R1 JAK2 CHRFAM7A

1.66e-031471215GO:0044853
GeneOntologyCellularComponentasymmetric synapse

DRP2 CNKSR2 CHRNA7 SEMA4C LRFN2 IGSF9B DMD CHRFAM7A CD200

1.84e-034771219GO:0032279
GeneOntologyCellularComponentsynaptic membrane

ACHE PI4K2A CNKSR2 CHRNA7 SEMA4C LRFN2 IGSF9B DMD CHRFAM7A UTRN

2.09e-0358312110GO:0097060
GeneOntologyCellularComponentnuclear body

SETD1A METTL3 NEK6 ATR ATRX BMP2K DTX1 APBB3 JADE1 DDX1 PTK6 ITPKC MTOR

2.21e-0390312113GO:0016604
GeneOntologyCellularComponentcell leading edge

REG1A REG1B ADGRV1 CHRNA7 PTK6 EGFR SNTG1 DMD CHRFAM7A

2.53e-035001219GO:0031252
GeneOntologyCellularComponentpostsynaptic specialization

DRP2 CNKSR2 CHRNA7 SEMA4C LRFN2 IGSF9B DMD CHRFAM7A CD200

2.63e-035031219GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

DRP2 CNKSR2 CHRNA7 SEMA4C LRFN2 IGSF9B DMD CHRFAM7A CD200

3.41e-035231219GO:0098984
GeneOntologyCellularComponentsite of polarized growth

LRRK2 PI4K2A REG1A REG1B CHRNA7 CHRFAM7A

3.58e-032531216GO:0030427
GeneOntologyCellularComponentmethyltransferase complex

SETD1A METTL3 CHD8 UTY

3.60e-031081214GO:0034708
GeneOntologyCellularComponentexocytic vesicle membrane

ATR LRRK2 PI4K2A SEMA4C DMD

3.89e-031791215GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATR LRRK2 PI4K2A SEMA4C DMD

3.89e-031791215GO:0030672
MousePhenoairway basal cell hyperplasia

CHRNA7 CHRFAM7A

5.70e-0521062MP:0011115
MousePhenoabnormal airway basal cell differentiation

CHRNA7 CHRFAM7A

5.70e-0521062MP:0011114
MousePhenoabnormal airway basal cell morphology

CHRNA7 CHRFAM7A

5.70e-0521062MP:0011113
DomainEF-hand_dom_typ1

DRP2 DMD UTRN

5.36e-0661223IPR015153
DomainEF-hand_dom_typ2

DRP2 DMD UTRN

5.36e-0661223IPR015154
DomainEF-hand_2

DRP2 DMD UTRN

5.36e-0661223PF09068
DomainEF-hand_3

DRP2 DMD UTRN

5.36e-0661223PF09069
DomainDystrophin

DMD UTRN

4.23e-0521222IPR016344
DomainKinase-like_dom

NEK6 ATR BMP2K WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR MTOR DMD EPHA3 EPHA5

5.49e-0554212213IPR011009
DomainWD40/YVTN_repeat-like_dom

CHAF1B IFT172 LRRK2 WDR27 BIRC6 WDFY4 SEMA4C PWP2 GNB2 WDR17

7.03e-0533512210IPR015943
DomainK_chnl_volt-dep_Kv6

KCNG1 KCNG4

1.26e-0431222IPR003969
DomainTPR-like_helical_dom

ATR IFT172 TTC3 XAB2 TTC7B MTOR PDCD11 UTY

1.48e-042331228IPR011990
DomainPI3_PI4_kinase

ATR PI4K2A MTOR

2.07e-04181223PF00454
DomainZF_ZZ_2

DRP2 DMD UTRN

2.07e-04181223PS50135
DomainPI3_4_KINASE_1

ATR PI4K2A MTOR

2.07e-04181223PS00915
DomainPI3_4_KINASE_2

ATR PI4K2A MTOR

2.07e-04181223PS00916
DomainZF_ZZ_1

DRP2 DMD UTRN

2.07e-04181223PS01357
DomainPI3/4_kinase_cat_dom

ATR PI4K2A MTOR

2.07e-04181223IPR000403
DomainZZ

DRP2 DMD UTRN

2.07e-04181223PF00569
DomainPI3_4_KINASE_3

ATR PI4K2A MTOR

2.07e-04181223PS50290
DomainZnf_ZZ

DRP2 DMD UTRN

2.44e-04191223IPR000433
DomainZnF_ZZ

DRP2 DMD UTRN

2.44e-04191223SM00291
DomainWW

DRP2 APBB3 DMD UTRN

2.49e-04471224PF00397
DomainWW

DRP2 APBB3 DMD UTRN

2.70e-04481224SM00456
DomainTyr_kinase_cat_dom

PTK6 JAK2 EGFR EPHA3 EPHA5

2.78e-04881225IPR020635
DomainTyrKc

PTK6 JAK2 EGFR EPHA3 EPHA5

2.78e-04881225SM00219
DomainSer-Thr/Tyr_kinase_cat_dom

NEK6 PTK6 JAK2 EGFR EPHA3 EPHA5

2.92e-041381226IPR001245
Domain-

CHAF1B IFT172 LRRK2 WDR27 BIRC6 WDFY4 SEMA4C GNB2 WDR17

3.41e-0433312292.130.10.10
DomainWW_DOMAIN_1

DRP2 APBB3 DMD UTRN

3.42e-04511224PS01159
DomainWW_DOMAIN_2

DRP2 APBB3 DMD UTRN

3.42e-04511224PS50020
DomainWW_dom

DRP2 APBB3 DMD UTRN

3.68e-04521224IPR001202
DomainWD40

CHAF1B IFT172 LRRK2 WDR27 WDFY4 PWP2 GNB2 WDR17

3.81e-042681228SM00320
DomainFATC

ATR MTOR

4.18e-0451222PF02260
DomainWD40_repeat

CHAF1B IFT172 LRRK2 WDR27 WDFY4 PWP2 GNB2 WDR17

4.20e-042721228IPR001680
Domain-

ATR TTC3 XAB2 TTC7B MTOR PDCD11 UTY

4.24e-0420712271.25.40.10
DomainPROTEIN_KINASE_TYR

PTK6 JAK2 EGFR EPHA3 EPHA5

4.37e-04971225PS00109
DomainTyr_kinase_AS

PTK6 JAK2 EGFR EPHA3 EPHA5

4.37e-04971225IPR008266
DomainSpectrin

DRP2 DMD UTRN

4.38e-04231223PF00435
DomainEphrin_rec_like

ELAPOR1 EPHA3 EPHA5

5.63e-04251223SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

ELAPOR1 EPHA3 EPHA5

5.63e-04251223IPR011641
DomainBRK

CHD8 CHD6

6.24e-0461222SM00592
DomainBRK_domain

CHD8 CHD6

6.24e-0461222IPR006576
DomainFAT

ATR MTOR

6.24e-0461222PS51189
DomainFATC

ATR MTOR

6.24e-0461222PS51190
DomainFAT

ATR MTOR

6.24e-0461222PF02259
DomainPIK-rel_kinase_FAT

ATR MTOR

6.24e-0461222IPR003151
DomainFATC_dom

ATR MTOR

6.24e-0461222IPR003152
DomainPIK_FAT

ATR MTOR

6.24e-0461222IPR014009
DomainBRK

CHD8 CHD6

6.24e-0461222PF07533
DomainFATC

ATR MTOR

6.24e-0461222SM01343
DomainDEXDc

BRIP1 ATRX CHD8 DDX1 CHD6

7.45e-041091225SM00487
DomainWD40_repeat_dom

CHAF1B IFT172 LRRK2 WDR27 WDFY4 PWP2 GNB2 WDR17

7.48e-042971228IPR017986
DomainHelicase_ATP-bd

BRIP1 ATRX CHD8 DDX1 CHD6

7.76e-041101225IPR014001
DomainProtein_kinase_ATP_BS

NEK6 WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR EPHA3 EPHA5

8.63e-043791229IPR017441
DomainPROTEIN_KINASE_ATP

NEK6 BMP2K WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR EPHA3 EPHA5

8.65e-0445912210PS00107
DomainSpectrin_repeat

DRP2 DMD UTRN

8.78e-04291223IPR002017
DomainEPL1

JADE3 JADE1

1.15e-0381222PF10513
DomainEnhancer_polycomb-like_N

JADE3 JADE1

1.15e-0381222IPR019542
DomainSNF2_N

ATRX CHD8 CHD6

1.17e-03321223IPR000330
DomainSNF2_N

ATRX CHD8 CHD6

1.17e-03321223PF00176
DomainSPEC

DRP2 DMD UTRN

1.17e-03321223SM00150
DomainSpectrin/alpha-actinin

DRP2 DMD UTRN

1.17e-03321223IPR018159
DomainProt_kinase_dom

NEK6 BMP2K WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR EPHA3 EPHA5

1.39e-0348912210IPR000719
DomainPROTEIN_KINASE_DOM

NEK6 BMP2K WEE1 LRRK2 PTK6 ULK3 JAK2 EGFR EPHA3 EPHA5

1.48e-0349312210PS50011
Domain-

HEXA MANBA AGL

1.53e-033512233.20.20.80
DomainDNA/RNA_helicase_DEAH_CS

BRIP1 CHD8 CHD6

1.53e-03351223IPR002464
DomainWD40

CHAF1B IFT172 WDR27 WDFY4 PWP2 GNB2 WDR17

1.57e-032591227PF00400
DomainPkinase_Tyr

PTK6 JAK2 EGFR EPHA3 EPHA5

1.58e-031291225PF07714
DomainGprotein_B

CHAF1B GNB2

1.84e-03101222IPR001632
DomainHAT

XAB2 PDCD11

1.84e-03101222SM00386
DomainHAT

XAB2 PDCD11

1.84e-03101222IPR003107
DomainGlyco_hydro_catalytic_dom

HEXA MANBA AGL

1.94e-03381223IPR013781
DomainDEAH_ATP_HELICASE

BRIP1 CHD8 CHD6

1.94e-03381223PS00690
DomainWD_REPEATS_1

CHAF1B IFT172 WDR27 WDFY4 PWP2 GNB2 WDR17

2.35e-032781227PS00678
DomainWD_REPEATS_2

CHAF1B IFT172 WDR27 WDFY4 PWP2 GNB2 WDR17

2.40e-032791227PS50082
DomainWD_REPEATS_REGION

CHAF1B IFT172 WDR27 WDFY4 PWP2 GNB2 WDR17

2.40e-032791227PS50294
DomainTPR-contain_dom

TTC3 XAB2 TTC7B PDCD11 UTY

3.05e-031501225IPR013026
Domain-

ATR LRRK2 WDFY4 AP1B1 MTOR ANKAR

3.39e-0322212261.25.10.10
DomainGrowth_fac_rcpt_

ATRN EGFR ELAPOR1 EPHA3 EPHA5

3.61e-031561225IPR009030
DomainRECEPTOR_TYR_KIN_V_2

EPHA3 EPHA5

3.66e-03141222PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA3 EPHA5

3.66e-03141222PS00790
DomainTyr_kinase_rcpt_V_CS

EPHA3 EPHA5

3.66e-03141222IPR001426
DomainEphA2_TM

EPHA3 EPHA5

3.66e-03141222PF14575
DomainEphrin_rcpt_lig-bd_dom

EPHA3 EPHA5

3.66e-03141222IPR001090
DomainEph_TM

EPHA3 EPHA5

3.66e-03141222IPR027936
DomainEPH_lbd

EPHA3 EPHA5

3.66e-03141222SM00615
DomainEphrin_lbd

EPHA3 EPHA5

3.66e-03141222PF01404
DomainTyr_kinase_ephrin_rcpt

EPHA3 EPHA5

3.66e-03141222IPR016257
DomainEPH_LBD

EPHA3 EPHA5

3.66e-03141222PS51550
DomainPI3/4_kinase_CS

ATR MTOR

4.20e-03151222IPR018936
DomainTPR_2

TTC3 XAB2 TTC7B

4.26e-03501223PF07719
DomainTPR_2

TTC3 XAB2 TTC7B

4.26e-03501223IPR013105
DomainWD40_repeat_CS

CHAF1B WDFY4 PWP2 GNB2 WDR17

4.46e-031641225IPR019775
Domain-

ATR MTOR

4.78e-031612221.10.1070.11
DomainPI3Kc

ATR MTOR

4.78e-03161222SM00146
DomainGlobin-like

ATR CYGB

4.78e-03161222IPR009050
DomainGlycoside_hydrolase_SF

HEXA MANBA AGL

5.02e-03531223IPR017853
DomainQuinoprotein_ADH-like_supfam

WDR27 PWP2 WDR17

5.02e-03531223IPR011047
DomainTPR_8

XAB2 TTC7B UTY

5.02e-03531223PF13181
DomainHelicase_C

ATRX CHD8 DDX1 CHD6

5.33e-031071224PF00271
DomainHELICc

ATRX CHD8 DDX1 CHD6

5.33e-031071224SM00490
DomainHelicase_C

ATRX CHD8 DDX1 CHD6

5.51e-031081224IPR001650
DomainHELICASE_CTER

ATRX CHD8 DDX1 CHD6

5.69e-031091224PS51194
PathwayREACTOME_PTK6_PROMOTES_HIF1A_STABILIZATION

LRRK2 PTK6 EGFR

6.22e-066973M27754
PathwayREACTOME_PTK6_PROMOTES_HIF1A_STABILIZATION

LRRK2 PTK6 EGFR

6.22e-066973MM15500
Pubmed

Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.

CHRNA7 DMD CHRFAM7A

4.42e-083124324833065
Pubmed

gamma-Syntrophin scaffolding is spatially and functionally distinct from that of the alpha/beta syntrophins.

DRP2 SNTG1 DMD UTRN

4.98e-0811124416857187
Pubmed

Sperm epidermal growth factor receptor (EGFR) mediates α7 acetylcholine receptor (AChR) activation to promote fertilization.

CHRNA7 EGFR CHRFAM7A

1.76e-074124322577141
Pubmed

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway.

CHRNA7 JAK2 CHRFAM7A

1.76e-074124316025117
Pubmed

Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.

MYH7 MTOR DMD

1.76e-074124325139234
Pubmed

α7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage.

CHRNA7 JAK2 CHRFAM7A

1.76e-074124328529954
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATRN NEK6 ATRX RNF213 WDR27 ATP9B ADGRV1 TTC3 PTK6 ZNF331 JAK2 POGLUT1 LRFN2 EGFR TBC1D22A ANKAR PLEKHA2 CHD6 IGSF9B UTRN

3.23e-0714891242028611215
Pubmed

Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.

DRP2 DMD UTRN

4.40e-075124311430802
Pubmed

Presynaptic type III neuregulin1-ErbB signaling targets {alpha}7 nicotinic acetylcholine receptors to axons.

CHRNA7 EGFR CHRFAM7A

4.40e-075124318458158
Pubmed

Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse.

DRP2 DMD UTRN

8.78e-07612439245586
Pubmed

Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion.

CHRNA7 DMD CHRFAM7A

8.78e-076124312079404
Pubmed

Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex.

DRP2 DMD UTRN

8.78e-076124310767429
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH7 NEK6 ATR ATRX BMP2K JADE3 WEE1 PTK6 CCNE1 ULK3 JAK2 AP1B1 EGFR IGSF9B UTRN

9.27e-079101241536736316
Pubmed

The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring.

ACHE CHRNA7 CHRFAM7A

1.53e-067124325683697
Pubmed

The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer.

LRRK2 PTK6 EGFR

2.45e-068124326751287
Pubmed

Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3.

CHRNA7 ADCYAP1R1 CHRFAM7A

5.21e-0610124318162309
Pubmed

Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.

ACHE DMD UTRN

7.15e-0611124310995443
Pubmed

Developmental alterations of the septohippocampal cholinergic projection in a lissencephalic mouse model.

ACHE CHRNA7 CHRFAM7A

9.51e-0612124326079645
Pubmed

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.

BRIP1 ATR ATRX

1.23e-0513124319064565
Pubmed

The protein tyrosine kinase family of the human genome.

PTK6 JAK2 EGFR EPHA3 EPHA5

1.23e-0583124511114734
Pubmed

Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.

DMD UTRN

1.26e-052124210525423
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRNA7 CHRFAM7A

1.26e-052124234453977
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.26e-052124223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRNA7 CHRFAM7A

1.26e-052124228258105
Pubmed

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

DMD UTRN

1.26e-052124228790199
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRNA7 CHRFAM7A

1.26e-052124219344760
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

1.26e-052124229114104
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRNA7 CHRFAM7A

1.26e-052124224836856
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRNA7 CHRFAM7A

1.26e-052124215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRNA7 CHRFAM7A

1.26e-052124235678315
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRNA7 CHRFAM7A

1.26e-052124212628457
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRNA7 CHRFAM7A

1.26e-052124222246862
Pubmed

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

DMD UTRN

1.26e-052124226974331
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRNA7 CHRFAM7A

1.26e-05212421400473
Pubmed

Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.

DMD UTRN

1.26e-05212427987307
Pubmed

Comparative analysis of the human dystrophin and utrophin gene structures.

DMD UTRN

1.26e-052124211861579
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRNA7 CHRFAM7A

1.26e-052124226937017
Pubmed

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

DMD UTRN

1.26e-052124230914715
Pubmed

A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm.

JAK2 EGFR

1.26e-052124228550306
Pubmed

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.

DMD UTRN

1.26e-052124217889902
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRNA7 CHRFAM7A

1.26e-052124216650968
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRNA7 CHRFAM7A

1.26e-052124224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRNA7 CHRFAM7A

1.26e-052124229261717
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRNA7 CHRFAM7A

1.26e-052124218199426
Pubmed

Cleavage of the Arg-Ile bond in the native polypeptide chain of human pancreatic stone protein.

REG1A REG1B

1.26e-05212423108036
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRNA7 CHRFAM7A

1.26e-052124218077004
Pubmed

The human reg gene encodes pancreatic stone protein.

REG1A REG1B

1.26e-05212422764894
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRNA7 CHRFAM7A

1.26e-052124219462340
Pubmed

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.

DMD UTRN

1.26e-052124237626761
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.26e-052124211790782
Pubmed

Pancreatic acinar-specific overexpression of Reg2 gene offered no protection against either experimental diabetes or pancreatitis in mice.

REG1A REG1B

1.26e-052124220489047
Pubmed

The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.

DMD UTRN

1.26e-052124226516677
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRNA7 CHRFAM7A

1.26e-052124237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRNA7 CHRFAM7A

1.26e-052124219631623
Pubmed

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

DMD UTRN

1.26e-052124222209498
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRNA7 CHRFAM7A

1.26e-052124215770102
Pubmed

Pancreatic regenerating gene overexpression in the nonobese diabetic mouse during active diabetogenesis.

REG1A REG1B

1.26e-05212428522062
Pubmed

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

DMD UTRN

1.26e-052124210694796
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRNA7 CHRFAM7A

1.26e-052124220720594
Pubmed

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.

CHRNA7 CHRFAM7A

1.26e-052124219368846
Pubmed

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

DMD UTRN

1.26e-052124224337461
Pubmed

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.

DMD UTRN

1.26e-052124211297940
Pubmed

The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.

CHRNA7 CHRFAM7A

1.26e-052124234514543
Pubmed

α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.

CHRNA7 CHRFAM7A

1.26e-052124222183893
Pubmed

Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.26e-052124212606407
Pubmed

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.

DMD UTRN

1.26e-052124222388933
Pubmed

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.

CHRNA7 CHRFAM7A

1.26e-052124224349346
Pubmed

Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.

CHRNA7 CHRFAM7A

1.26e-052124216319313
Pubmed

EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis.

MTOR EPHA3

1.26e-052124231262977
Pubmed

Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.

CHRNA7 CHRFAM7A

1.26e-052124225797465
Pubmed

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.

CHRNA7 CHRFAM7A

1.26e-052124229197398
Pubmed

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

CHRNA7 CHRFAM7A

1.26e-052124238178134
Pubmed

In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

1.26e-052124223325242
Pubmed

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.

DMD UTRN

1.26e-052124228785010
Pubmed

Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice.

REG1A REG1B

1.26e-052124223986224
Pubmed

Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.

DMD UTRN

1.26e-052124216307000
Pubmed

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.

CHRNA7 CHRFAM7A

1.26e-052124221901321
Pubmed

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

EGFR MTOR

1.26e-052124215657358
Pubmed

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.

DMD UTRN

1.26e-052124221949353
Pubmed

Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.

CHRNA7 CHRFAM7A

1.26e-052124220624304
Pubmed

Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

DMD UTRN

1.26e-052124223097179
Pubmed

The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.

DMD UTRN

1.26e-052124215501597
Pubmed

Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth.

CHRNA7 CHRFAM7A

1.26e-052124210800961
Pubmed

Characterization of allelic variants at chromosome 15q14 in schizophrenia.

CHRNA7 CHRFAM7A

1.26e-052124216417613
Pubmed

Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.

CHRNA7 CHRFAM7A

1.26e-052124211834293
Pubmed

Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells.

AP1B1 EGFR

1.26e-052124223205726
Pubmed

Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.

DMD UTRN

1.26e-052124218973234
Pubmed

RegII is a beta-cell protein and autoantigen in diabetes of NOD mice.

REG1A REG1B

1.26e-052124217192462
Pubmed

Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis.

CHRNA7 CHRFAM7A

1.26e-052124234512319
Pubmed

Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation.

REG1A REG1B

1.26e-05212428654365
Pubmed

Visual acuity is reduced in alpha 7 nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.26e-052124222281823
Pubmed

Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.

DMD UTRN

1.26e-052124227881412
Pubmed

Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium.

CHRNA7 CHRFAM7A

1.26e-052124212391028
Pubmed

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.

DMD UTRN

1.26e-052124229065908
Pubmed

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.

DMD UTRN

1.26e-052124231039133
Pubmed

Mouse muscle denervation increases expression of an alpha7 nicotinic receptor with unusual pharmacology.

CHRNA7 CHRFAM7A

1.26e-052124212562921
Pubmed

Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.

DMD UTRN

1.26e-05212428159184
Pubmed

Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.

DMD UTRN

1.26e-052124210679963
Pubmed

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.

DMD UTRN

1.26e-052124221565990
Pubmed

Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.

DMD UTRN

1.26e-05212428186702
InteractionDRP2 interactions

DRP2 SNTG1 DMD UTRN

3.95e-07111214int:DRP2
InteractionSNTG1 interactions

DRP2 SNTG1 PLEKHA2 DMD UTRN

1.27e-06321215int:SNTG1
InteractionREG1B interactions

REG1A REG1B GNB2

4.17e-0661213int:REG1B
InteractionLINC01139 interactions

LRRK2 PTK6 EGFR

4.17e-0661213int:LINC01139
Cytoband6p21.2-p21.1

KCNK16 LRFN2

7.24e-06212426p21.2-p21.1
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 DMD UTRN

9.22e-051890391
GeneFamilyWD repeat domain containing

CHAF1B IFT172 WDR27 WDFY4 PWP2 GNB2 WDR17

3.32e-04262907362
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ATRN REG1A REG1B

1.11e-03419031298
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA3 EPHA5

2.14e-03149021095
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACHE CYGB ADCYAP1R1 GPR83 SNTG1 CHD6

7.59e-06169123678eb70dd916724e476eabccf18fb7fcec4210308
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B WEE1 LRRK2 RBP4 PTK6 EGFR

7.59e-0616912368f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell356C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

JADE3 ACHE CHRNA7 POGLUT1 SNX11 CD200

7.59e-06169123644d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

JADE3 ACHE CHRNA7 POGLUT1 SNX11 CD200

7.85e-061701236513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTX1 WDFY4 CCNE1 JAK2 PLEKHA2 ZNF292

7.85e-0617012366210ee3bf29059e6149c047bb7e02c5f59441519
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYH7 JADE3 ACHE POGLUT1 CHRFAM7A CD200

1.09e-05180123632d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYH7 JADE3 ACHE POGLUT1 CHRFAM7A CD200

1.09e-051801236067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI4K2A ITPKC EGFR DMD UTRN UTY

1.27e-051851236eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

MANBA NEK6 BMP2K LRRK2 WDFY4 TBC1D22A

1.43e-05189123614f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACHE TTC3 GPR83 SNTG1 WDR17 EPHA5

1.52e-0519112365d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACHE TTC3 GPR83 SNTG1 WDR17 EPHA5

1.52e-05191123673dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ATRN ATR ATRX ADGRV1 BIRC6 UTRN

1.62e-051931236abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACHE JAK2 POGLUT1 SNX11 CHRFAM7A CD200

1.97e-052001236a4c41509ca936e137230a6ae548c90f18a566d12
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ATRX RNF213 BIRC6 JAK2 UTRN ZNF292

1.97e-05200123612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Npsr1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBXO47 CLDN23 KCNG1 PADI6

7.52e-058112345d9b08bc1ae6ecb894c88c9784fdc4203682d087
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K POLR3A FANCC UTY ALG13

7.76e-0515812351d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PKD1L1 CYGB IL18R1 UTRN UTY

9.25e-051641235b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRP2 GCM2 ACHE CNKSR2 IGSF9B

9.25e-0516412353caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell356C-Myeloid-Dendritic-cDC_activated|356C / Donor, Lineage, Cell class and subclass (all cells)

ACHE CHRNA7 POGLUT1 SNX11 CD200

1.01e-04167123543a9375fdbafd7450c553e4620e21537e08639dd
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYGB MTX2 KCNG1 KCNG4 WDR17

1.01e-04167123555c3c68af269fcf40f2b080ae4489523609ad388
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ACHE CYGB CCNE1 MTX2 CHD6

1.06e-041691235c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCellmetastatic_Lymph_Node-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

ZNF331 PKM RORB DMD CD200

1.06e-0416912353d48acea7482bbe5bb9da4c3af5f9b0c9800122f
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

BMP2K ACHE POGLUT1 SNX11 CD200

1.09e-0417012354ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NEK6 CYGB LRFN2 RORB CD200

1.09e-041701235a50e558d0b38100ccbdccb90647fe93e85bffd86
ToppCellILEUM-non-inflamed-(3)_mature_DC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MYH7 NEK6 ACHE POGLUT1 CD200

1.09e-04170123560151394460e6f27a42fab434e8b7b2adc78b128
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NEK6 JADE3 ACHE POGLUT1 CD200

1.13e-041711235341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WEE1 CHRNA7 EGFR KCNG1 CHRFAM7A

1.19e-041731235af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7 MANBA KCNK16 IL18R1 CD200

1.25e-0417512350992de1c7bffcb6890584357a7a0a8955927da6c
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1B LRRK2 RBP4 PTK6 EGFR

1.29e-04176123533323c97afe509147956b8df9f92ca6b0537e604
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACHE WDFY4 CHRNA7 POGLUT1 CHRFAM7A

1.32e-041771235aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACHE WDFY4 CHRNA7 POGLUT1 CHRFAM7A

1.32e-041771235d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACHE WDFY4 CHRNA7 POGLUT1 CHRFAM7A

1.32e-04177123570ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RBP4 ELAPOR1 RORB DMD

1.32e-041771235426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE RBP4 RASGEF1A KCNG4 CD200

1.39e-0417912357c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|356C / Donor, Lineage, Cell class and subclass (all cells)

SETD1A POLR3A CLCN2 MTOR PWP2

1.39e-041791235f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GCM2 ZPLD1 RBP4 KCNK16 ELAPOR1

1.43e-0418012350c5d9245b8a7cc34ad52522d31559906cda55bdf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TTC3 SERINC1 CD200 EPHA3

1.45e-0496123456e993d37b7958abe56682422536045550e29b41
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CHRNA7 ADCYAP1R1 EGFR KCNG1 CHRFAM7A

1.47e-04181123503a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-2|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AARS2 KCNG1 ANKAR PWP2 CD200

1.47e-04181123575035a3211e524bb659b82e6979f7d3a3121ae70
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 LRFN2 IGSF9B CD200 EPHA3

1.47e-0418112355f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 NIBAN2 CLDN23 AARS2 PDCD11

1.47e-041811235709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSPAN12 LRFN2 IGSF9B CD200 EPHA3

1.47e-041811235c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellB_cells-Naive_B_cells_|World / Immune cells in Kidney/Urine in Lupus Nephritis

DTX1 WDFY4 KCNG1 PLEKHA2 CD200

1.51e-04182123563c3b63315276b66667d49fab09661ac320e7a36
ToppCellfacs-Kidney-nan-3m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 ATRN RBP4 SEMA4C CD200

1.51e-0418212354c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRODH2 SLC10A2 CLCN2 EGFR AGL

1.54e-041831235d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHAF1B BRIP1 ZFAND4 CCNE1 ALG13

1.54e-0418312356c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 CNKSR2 ADGRV1 DMD EPHA5

1.58e-0418412352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 CNKSR2 ADGRV1 DMD EPHA5

1.58e-041841235ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 CNKSR2 ADGRV1 DMD EPHA5

1.58e-0418412352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSPAN12 CHRNA7 EGFR KCNG1 CHRFAM7A

1.63e-0418512354c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 ELAPOR1 SNTG1 RORB UTRN

1.63e-0418512355a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellIPF-Myeloid-DC_Mature|World / Disease state, Lineage and Cell class

BMP2K JADE3 ACHE POGLUT1 CD200

1.67e-041861235d0d3953d9b199e0e792990b8551efb993393fe7e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSPAN12 CHRNA7 EGFR KCNG1 CHRFAM7A

1.67e-041861235fef543f188edb0d1704d9c6ace366a0f8017bf53
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 FANCC EGFR CD200 LYG1

1.67e-0418612355c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

BRIP1 RNF213 BIRC6 UTY ZNF292

1.67e-0418612358571956890fc9894d766ba294a28e376b4aba428
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SETD1A POLR3A CLCN2 MTOR PWP2

1.71e-041871235c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

MANBA NEK6 JADE3 LRRK2 WDFY4

1.71e-0418712354e64be635f445276e71f2937f33f041c3a4204ab
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATRN PRODH2 SNTG1 DMD SLC23A2

1.71e-041871235f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDFY4 TIMP3 KCNG1 PLEKHA2 CD200

1.71e-041871235d01926be1c8846a25fb6706e26b56b808b69f8f0
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

MANBA NEK6 BMP2K JADE3 WDFY4

1.71e-041871235af1327559f7e01bec070881cae52834917c3da65
ToppCellCOPD-Myeloid-DC_Mature|COPD / Disease state, Lineage and Cell class

BMP2K JADE3 ACHE POGLUT1 CD200

1.75e-041881235de93ccb53edb8599da9e312db0e3af604c21f673
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC3 GPR83 LRP10 PKM TECPR1

1.75e-041881235e0184d9f6687d7ecb8fc461294ff7208f49c437c
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRP2 RBP4 CYGB ADCYAP1R1 FAM237B

1.75e-041881235bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

ZNF331 ITPKC EGFR CD200 ALG13

1.80e-04189123546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SETD1A POLR3A CLCN2 MTOR PWP2

1.80e-04189123599b01893da9f9f7c9528afaffad178285211738b
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ATRX REG1A TTC3 CHD6 ZNF292

1.80e-041891235a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACHE RBP4 RASGEF1A KCNK16 CD200

1.80e-041891235fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DTX1 WDFY4 KCNG1 PLEKHA2 CD200

1.84e-041901235112706d64ee73b55dcf76f33ca064ab1fc6ce87f
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBP4 CYGB TIMP3 SNTG1 EPHA5

1.84e-04190123597772e69e6f51ebffbb5433ca7b40f1048723220
ToppCellfacs-Skin-Anagen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX1 LRP10 SERINC1 PKM UTY

1.84e-041901235888ded899f0513d41bf655896d59ae8ef74e0978
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC3 GPR83 LRP10 PKM TECPR1

1.84e-0419012358f5e71a0861ee4e8f3ce45e8a7f18fb9d6036a3c
ToppCelldroplet-Lung-nan-18m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBP4 CYGB TIMP3 SNTG1 EPHA5

1.84e-04190123572c2b824acdc43139e6635785df3ed3feb58ec46
ToppCellfacs-Skin-Anagen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX1 LRP10 SERINC1 PKM UTY

1.84e-0419012353466cebab16964e94da130d0673fa32e7d90b5ed
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

MANBA NEK6 BMP2K JADE3 WDFY4

1.84e-0419012351e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RNF213 BIRC6 IL18R1 UTY ZNF292

1.88e-0419112359454f642c3621370fa23640b631301346b300950
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TIMP3 IGSF9B DMD UTRN EPHA3

1.88e-04191123504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellCOVID-19_Severe-B_intermediate|World / disease group, cell group and cell class

JADE3 DTX1 CNKSR2 WDFY4 DMD

1.88e-041911235f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACHE CHRNA7 ADCYAP1R1 EGFR CHRFAM7A

1.93e-0419212353abee376c37c3646da33ac381aa63d50a01607a6
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ATRN SNTG1 CHD6 UTRN ZNF292

1.93e-041921235916fbec1c7ab7969bda711886ac88e877e30c280
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 ACHE RBP4 RASGEF1A CD200

1.93e-041921235550a6574a93acadb43c449094565c73ca51a0c5c
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK16 ADGRV1 PRODH2 ELAPOR1 SNTG1

1.93e-0419212355692bd57093852d442400383850f416c497dcc7d
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

BMP2K ACHE POGLUT1 SNX11 CD200

1.98e-041931235024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ATRN SNTG1 CHD6 UTRN ZNF292

1.98e-041931235e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 ACHE RBP4 RASGEF1A CD200

1.98e-0419312357fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-Naive_B_cells|lymph-node_spleen / Manually curated celltypes from each tissue

WDFY4 AP1B1 KCNG1 PLEKHA2 CD200

2.03e-04194123520967afbadb3cf80ba9f4d7ebda4e64389252e70
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

MANBA BMP2K WDFY4 ZNF331 AP1B1

2.07e-041951235c172c5599379c29123340621a36bfb1fc90c2115
ToppCellcontrol-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BMP2K WDFY4 KCNG1 PLEKHA2 CD200

2.07e-041951235ff7956624b36df34e55295b295a71585accf07bd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

ATRX TTC3 ELAPOR1 EPHA3 ZNF292

2.12e-04196123538da0751941adca650fe9b383d9f343153978eb5
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTX1 WDFY4 KCNG1 PLEKHA2 CD200

2.12e-041961235d7e6c89cb49933b4a86d26d15f6772f2481d37ef
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn|World / Primary Cells by Cluster

ATRX TTC3 ELAPOR1 EPHA3 ZNF292

2.12e-041961235721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DTX1 WDFY4 KCNG1 PLEKHA2 CD200

2.12e-041961235fcbfd8c4771d99a45fc53e482ef98edabe8ef591
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 DRP2 TTC3 DMD CD200

2.12e-04196123597ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DTX1 WDFY4 KCNG1 PLEKHA2 CD200

2.12e-041961235f45cb8f714ae7ac800768df65f299b98a2d42962
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MANBA BMP2K WDFY4 ZNF331 CD300E

2.12e-0419612357026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HEXA MANBA ATP9B ZNF331 CHRFAM7A

2.12e-0419612355fe6534af65d43eeacd4b031310242b4f706008b
ToppCellmild-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BMP2K WDFY4 KCNG1 PLEKHA2 CD200

2.12e-0419612351988088dd7e1ba947339fd1331beed482955e607
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NEK6 APBB3 AARS2 CD300E

2.13e-041061234005ca899efc5ad0c9c17b2697022b594c8cea2c1
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ACHE ULK3 ELAPOR1 CD200 LYG1

2.18e-0419712354f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 SEMA4C UTRN IMPG2 ZNF292

2.18e-041971235e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell390C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NEK6 BMP2K ACHE POGLUT1 CD200

2.18e-041971235311438418f3d697e54222da111014c887fd815f5
DiseaseSquamous cell carcinoma of lung

ATR BMP2K EGFR EPHA3 EPHA5

1.81e-07321195C0149782
DiseaseLarge cell carcinoma of lung

ATR MTOR EPHA3 EPHA5

8.29e-06321194C0345958
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

DRP2 SNTG1 DMD UTRN

1.34e-05361194DOID:11723 (implicated_via_orthology)
DiseaseMalignant Neoplasms

ATR BIRC6 CCNE1 EGFR MTOR EPHA3

1.38e-051281196C0006826
Diseasecolon cancer (biomarker_via_orthology)

REG1A REG1B JAK2 MTOR

1.85e-05391194DOID:219 (biomarker_via_orthology)
DiseaseBladder Neoplasm

ACHE FANCC CCNE1 EGFR MTOR CHD6

2.29e-051401196C0005695
DiseaseMalignant neoplasm of urinary bladder

ACHE FANCC CCNE1 EGFR MTOR CHD6

2.38e-051411196C0005684
Diseaseliver cancer (biomarker_via_orthology)

CCNE1 JAK2

1.60e-0451192DOID:3571 (biomarker_via_orthology)
Diseaseschizophrenia (implicated_via_orthology)

SETD1A CHRNA7 MTOR CHRFAM7A

1.68e-04681194DOID:5419 (implicated_via_orthology)
Diseaseovarian neoplasm

BRIP1 ATR CCNE1 EGFR MTOR

2.16e-041341195C0919267
Diseasecognitive disorder (implicated_via_orthology)

CHRNA7 CHRFAM7A

2.39e-0461192DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRNA7 CHRFAM7A

2.39e-0461192DOID:7148 (biomarker_via_orthology)
DiseaseMalignant neoplasm of ovary

BRIP1 ATR CCNE1 EGFR MTOR

2.40e-041371195C1140680
DiseaseMental Retardation, X-Linked 1

CNKSR2 DMD ALG13

2.91e-04321193C2931498
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH7 EGFR TIMP3 DMD

3.14e-04801194DOID:12930 (implicated_via_orthology)
Diseaselithostathine-1-alpha measurement

REG1A REG1B

3.34e-0471192EFO_0801083
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD8 CHD6

3.34e-0471192DOID:0050834 (implicated_via_orthology)
Diseaseobsolete_interleukin-1 alpha measurement

REG1A REG1B

3.34e-0471192EFO_0802653
Diseaseinfertility (implicated_via_orthology)

METTL3 GCM2

3.34e-0471192DOID:5223 (implicated_via_orthology)
Diseasecervical cancer

JAK2 EGFR MTOR

3.49e-04341193C4048328
DiseaseUterine Cervical Neoplasm

JAK2 EGFR MTOR

3.81e-04351193C0007873
DiseaseGlioma

ATR ATRX CLCN2 EGFR

4.32e-04871194C0017638
DiseaseMuscular Dystrophy

ACHE DMD

4.44e-0481192C0026850
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma

REG1A TBC1D22A DMD

5.26e-04391193EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Diseasehigh grade glioma (is_marker_for)

CHAF1B EGFR MTOR

6.55e-04421193DOID:3070 (is_marker_for)
DiseaseMalignant Head and Neck Neoplasm

BRIP1 FANCC EGFR

7.51e-04441193C0278996
DiseaseAshkenazi Jewish disorders

HEXA FANCC

8.66e-04111192cv:CN118946
DiseaseNeoplasm Invasiveness

CHRNA7 EGFR TIMP3 PKM DMD

9.19e-041841195C0027626
DiseaseCardiomyopathy, Dilated

MYH7 EGFR DMD

9.69e-04481193C0007193
Diseasenicotine dependence (implicated_via_orthology)

CHRNA7 CHRFAM7A

1.04e-03121192DOID:0050742 (implicated_via_orthology)
DiseaseCardiomyopathy, Familial Idiopathic

MYH7 EGFR DMD

1.09e-03501193C1449563
Diseasepancreatic cancer (is_implicated_in)

ATR FANCC EGFR EPHA3

1.12e-031121194DOID:1793 (is_implicated_in)
DiseaseSquamous cell carcinoma of the head and neck

WEE1 CCNE1 EGFR

1.22e-03521193C1168401
DiseaseFanconi anemia

BRIP1 FANCC

1.42e-03141192cv:C0015625
Diseaseleukemia

BRIP1 FANCC JAK2

1.44e-03551193C0023418
DiseaseNeoplasm of uncertain or unknown behavior of bladder

FANCC MTOR

1.64e-03151192C0496930
DiseaseBenign neoplasm of bladder

FANCC MTOR

1.64e-03151192C0154017
DiseaseCarcinoma in situ of bladder

FANCC MTOR

1.64e-03151192C0154091
DiseaseDisorder of eye

TSPAN12 RBP4 ADGRV1 TIMP3 IMPG2

1.72e-032121195C0015397
Diseaserenal cell carcinoma (is_marker_for)

CCNE1 EGFR TIMP3 MTOR

1.83e-031281194DOID:4450 (is_marker_for)
Diseaseovarian carcinoma

BRIP1 PKD1L1 ADGRV1 AARS2 SNTG1 DMD

1.96e-033211196EFO_0001075
DiseaseIntellectual Disability

HEXA SETD1A CHD8 AP1B1 MTOR ZNF292 ALG13

2.29e-034471197C3714756
Diseasehypertension (biomarker_via_orthology)

MYH7 RBP4 CCNE1 EGFR PKM

2.31e-032271195DOID:10763 (biomarker_via_orthology)
DiseaseMalignant neoplasm of endometrium

ATR EGFR

2.37e-03181192C0007103
DiseaseBone marrow hypocellularity

BRIP1 FANCC

2.37e-03181192C1855710
DiseaseCarcinoma of bladder

FANCC MTOR

2.37e-03181192C0699885
DiseaseCarcinoma in situ of endometrium

ATR EGFR

2.37e-03181192C0346191
Diseasebreast carcinoma (is_marker_for)

BRIP1 EGFR TIMP3

2.43e-03661193DOID:3459 (is_marker_for)
DiseaseParkinson's disease (is_marker_for)

ACHE LRRK2 EGFR

2.54e-03671193DOID:14330 (is_marker_for)
DiseaseMYELODYSPLASTIC SYNDROME

BRIP1 ATRX FANCC

2.54e-03671193C3463824
Diseaseportal hypertension (implicated_via_orthology)

JAK2 MTOR

2.64e-03191192DOID:10762 (implicated_via_orthology)
Diseaseatherosclerosis (biomarker_via_orthology)

RBP4 JAK2

2.92e-03201192DOID:1936 (biomarker_via_orthology)
Diseasehemorrhoid

BRIP1 BIRC6 AP1B1 EGFR

3.01e-031471194EFO_0009552
Diseasemuscular dystrophy (implicated_via_orthology)

DMD UTRN

3.22e-03211192DOID:9884 (implicated_via_orthology)
DiseaseNystagmus

REG1A REG1B

3.22e-03211192HP_0000639
Diseasestatus epilepticus (implicated_via_orthology)

CASP6 MTOR

3.22e-03211192DOID:1824 (implicated_via_orthology)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

CHRNA7 JAK2 EGFR

3.37e-03741193DOID:3748 (is_marker_for)
DiseaseOvarian Serous Adenocarcinoma

LRRK2 JAK2

3.86e-03231192C1335177
DiseaseCarcinoma of lung

EGFR EPHA3

3.86e-03231192C0684249
DiseaseAlzheimer's disease (is_marker_for)

BRIP1 ATR CASP6 REG1A CHRNA7

3.93e-032571195DOID:10652 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MWNPNRELSEDCLYL

ACHE

116

P22303
WYNRQNCILADEMGL

CHD8

826

Q9HCK8
NRMEEWGACYNAENI

ALG13

416

Q9NP73
GAWAQYSLTCMLQDI

BIRC6

2401

Q9NR09
MQNLNEDDAGSYWCK

CD300E

91

Q496F6
ALYQLMLDCWQKERN

EPHA5

906

P54756
LIGQDMSALYCWNSE

ADGRV1

3521

Q8WXG9
ELMQKVSGYQWCDIE

CCNE1

311

P24864
DVYDICWATDGNLMA

CHAF1B

131

Q13112
EWGQIFILDCLANYM

AP1B1

216

Q10567
DMCLNWLLNVYDTGR

DMD

3176

P11532
DNVWEVLILMEYCRA

BMP2K

121

Q9NSY1
WSLDLQMQEADISGY

CHRNA7

176

P36544
EAWYEGNLGAMLRCV

PRODH2

201

Q9UF12
KWAELANLINNCMDY

JAK2

776

O60674
NREDGYLWGLDNMIC

ITPKC

661

Q96DU7
IEWTFIDFGMDLQAC

MYH7

506

P12883
ELYGTWEMLCGNEVQ

NIBAN2

221

Q96TA1
VMSLEVICLANDQYW

ANKAR

721

Q7Z5J8
QMDDITCYWENLLSE

POGLUT1

351

Q8NBL1
NRLGRWLQDEMAFCY

PADI6

351

Q6TGC4
NCSALLNEEDVIYWM

IL18R1

236

Q13478
LSYSQDWLMCLQEEF

LRP10

131

Q7Z4F1
ENYTCLDQWAMEQFV

KCNK16

56

Q96T55
LLNSSMCLEDSRYNW

ATRN

1041

O75882
IVQYNDWLEEECGNM

ATP9B

666

O43861
SEPSAECWQNMYKLL

KIAA1109

2696

Q2LD37
ACDANGETQLMYKWA

ELAPOR1

341

Q6UXG2
QEMCALSFQEELAYW

KCNG4

136

Q8TDN1
DWQDCISGINSMIYC

BEND2

561

Q8NDZ0
ETVNGSWYIQDLCEM

CASP6

221

P55212
DGGCTIWYNEMQLLS

DDX1

646

Q92499
DKVCLWLGANVMLEY

VBP1

121

P61758
WSLGCLLYEMAALQS

NEK6

231

Q9HC98
VQEAACWALNNLLMY

LRRK2

366

Q5S007
NAYMEKCDENILWLD

PKM

146

P14618
LAGYDDFNCNIWDAM

GNB2

286

P62879
EMCALSFQEELLYWG

KCNG1

141

Q9UIX4
LWLCNMIGDVTTEQY

GPR83

266

Q9NYM4
WSLDLQMQEADISGY

CHRFAM7A

86

Q494W8
GAWTAYDMDICITIQ

DTX1

116

Q86Y01
AMELGRECLNLWGYE

METTL3

436

Q86U44
TLRLYFDDTGCWDMN

ADCYAP1R1

286

P41586
AALDLYVEQGQWDKC

IFT172

1416

Q9UG01
DIAWQVAEGMCYLES

PTK6

291

Q13882
ITFWNITLEDEGCYM

CD200

106

P41217
YESACKIWSGNEMLL

BRIP1

461

Q9BX63
NDNWLIKYDCPMDSS

PI4K2A

311

Q9BTU6
NWCVQIAKGMNYLED

EGFR

816

P00533
YMLAIILVNCDDDLW

APBB3

6

O95704
KELSTIMDENNQWYC

ATRX

251

P46100
EATDENLLCQMYLGW

ATR

2626

Q13535
WYNRKNCILADEMGL

CHD6

476

Q8TD26
AVQAMWARLYANCED

CYGB

26

Q8WWM9
MAQDSVDLSCDYQFW

FANCC

1

Q00597
AALYQLMLDCWQKDR

EPHA3

851

P29320
YELCDELGIMVWQDF

MANBA

401

O00462
LALMDLSESSNWGCY

LYG1

11

Q8N1E2
MFLQTLTAGWDELEC

FBXO47

166

Q5MNV8
LNIAQDFWDMYVDCL

FAM237B

91

A0A1B0GVD1
FCDISQGLSYTWNLM

PKD1L1

706

Q8TDX9
VDVELYQGLWDMCRE

CLDN23

41

Q96B33
FWLQELNEDLAEMGC

JADE3

146

Q92613
CVDMSLNWLLNVFDS

DRP2

471

Q13474
TWVDADLYCQNMNSG

REG1A

56

P05451
TWVDADLYCQNMNSG

REG1B

56

P48304
ASNILAYWVDGDMDL

SLC10A2

111

Q12908
SQWAFCMENILGLNL

PPEF1

506

O14829
NQAYGRDLMEAQEWC

MTOR

2071

P42345
MLLTAELYLQWCDEA

MTX2

121

O75431
EACMWGEYVDNTNLV

HEXA

456

P06865
VDMCINGVAGQDYWA

MS4A12

181

Q9NXJ0
ILDTQANCLLWYMDN

PLEKHA2

31

Q9HB19
CVDMCLNWLLNVYDT

UTRN

2931

P46939
AWMDLGTLYESCNQP

UTY

351

O14607
RLWLDYCQFLMDQGR

XAB2

111

Q9HCS7
ILRYAMSNCGWAQEE

SNX11

151

Q9Y5W9
IDAWDMTIAYCTNNA

NXPE2

526

Q96DL1
YMGWCEAREQDPLQD

SNTG1

286

Q9NSN8
GVCSYGMQLSWDIND

GCM2

11

O75603
IMEDWDFLQLQCALY

POLR3A

306

O14802
DQMNWCDSAIEYLLD

SMG9

186

Q9H0W8
QTMGRCWDENQYLLC

THNSL2

376

Q86YJ6
QIQRYCELMVELGEW

WDR17

831

Q8IZU2
YWMNLCEDGVTSIFE

IMPG2

136

Q9BZV3
YDLNDMDAAWLELTN

JADE1

141

Q6IE81
VFQAQWGDMYLSAIC

SEMA4C

316

Q9C0C4
WGDMYLSAICEYQLE

SEMA4C

321

Q9C0C4
ILYDIWNSGLDSEDM

SETD1A

1426

O15047
EEACNMAWELLTQVY

AARS2

146

Q5JTZ9
MEEGNSRCWYAALLS

SERINC1

186

Q9NRX5
WVMDYAIAACLQAQQ

CLCN2

106

P51788
IMNADILAYCQKEGW

CNIH1

106

O95406
VVDWMKGLDDCLQQY

CNKSR2

16

Q8WXI2
REDYQLVMVCDGDWE

RNF213

1921

Q63HN8
WVALLNLENMYGSQE

PDCD11

1661

Q14690
EEWQCLDMAQQNLYR

ZNF99

16

A8MXY4
WAEDDHMLIQNEYCN

WEE1

366

P30291
ATNLDGRWNVLMDYC

ZPLD1

221

Q8TCW7
VMLENYWNLVSLGLC

ZNF160

36

Q9HCG1
AAGMVAGWLINCYQD

ZNF778

26

Q96MU6
YDNWFNCLSMLVATE

RASGEF1A

266

Q8N9B8
LYVGDNWNKCDMVAI

TRPM5

801

Q9NZQ8
DAMCVGYDQWATSQL

SLC23A2

126

Q9UGH3
EDQGWYECKVLMLDQ

IGSF9B

106

Q9UPX0
LDLYSLSQDGVLCMW

PWP2

201

Q15269
LLNNWDVCADMVGTF

RBP4

81

P02753
AGQYWEMCKDSQLEF

TECPR1

21

Q7Z6L1
ETCQYTMEELHQLAW

RORB

236

Q92753
SRQLQQGDMYCAWEL

ZNF292

281

O60281
LCNFELWMNTADNLE

WDFY4

1466

Q6ZS81
ACLNSAQRDLYWDVM

ZNF331

21

Q9NQX6
MLDNCKYLASLGNWT

ZNF840P

71

A6NDX5
CDALSMLGEYDWALQ

TTC3

306

P53804
VELACGVWTYEQELM

TSPAN12

106

O95859
ADTYWCMSKLLDGIQ

TBC1D22A

361

Q8WUA7
QEEWECLDADQMNLY

ZNF829

46

Q3KNS6
QWEIMESLTSYGLEC

ZNF582

101

Q96NG8
GCQEESWLQSEYDEM

nan

336

Q3C1V9
AEILLRGMCEQSYWN

TTC7B

266

Q86TV6
ASLDYVIMWNLDECR

WDR27

91

A2RRH5
IWNNMELENDYCLND

ZFAND4

71

Q86XD8
NECLWTDMLSNFGYP

TIMP3

161

P35625
QWDSDNIYLIMEFCA

ULK3

81

Q6PHR2
FCNNLRSGDWMIDYV

AGL

956

P35573
GYDLCVLAMWDDTAT

LRFN2

486

Q9ULH4
LTLEQEYAMQCSWQE

NAT9

46

Q9BTE0