Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA topoisomerase type I (single strand cut, ATP-independent) activity

TOP1MT TOP3B TOP1

2.45e-0641713GO:0003917
GeneOntologyMolecularFunctionsupercoiled DNA binding

HMGB1 HMGB2 TOP1

1.21e-0561713GO:0097100
GeneOntologyMolecularFunctionfour-way junction DNA binding

HMGB1 HMGB2 HMGB3 MECP2

1.82e-05191714GO:0000400
GeneOntologyMolecularFunctionDNA binding, bending

HMGB1 HMGB2 HMGB3 TOP1

2.26e-05201714GO:0008301
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP1MT TOP3B TOP1

3.35e-0581713GO:0003916
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

7.29e-0521712GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

7.29e-0521712GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

2.18e-0431712GO:0043993
GeneOntologyMolecularFunctionRAGE receptor binding

HMGB1 HMGB2 S100A8

2.60e-04151713GO:0050786
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP MCM3AP EP300

2.60e-04151713GO:0010484
GeneOntologyMolecularFunctionDNA secondary structure binding

HMGB1 HMGB2 HMGB3 MECP2

4.11e-04411714GO:0000217
GeneOntologyMolecularFunctionN-acetyltransferase activity

NAT8L NAA15 CREBBP MCM3AP EP300

5.54e-04781715GO:0008080
GeneOntologyBiologicalProcessDNA topological change

HMGB1 HMGB2 TOP1MT TOP3B TOP1

8.48e-09101695GO:0006265
GeneOntologyBiologicalProcessDNA conformation change

MCM8 HMGB1 HMGB2 HMGB3 RAD54B TOP1MT DNA2 TOP3B TOP1

7.88e-08941699GO:0071103
GeneOntologyBiologicalProcessDNA damage response

CUL4A CIDEB SMG1 VPS72 FLYWCH1 MCM8 UACA SGK1 RRM2B HMGB1 HMGB2 SSRP1 CREBBP RINT1 YEATS4 PSME4 SMC3 RAD54B PRKDC DNA2 MNDA TOP3B EP300

3.76e-0695916923GO:0006974
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

NAA15 CREBBP NAA25 EP300

7.33e-06161694GO:0006474
GeneOntologyBiologicalProcessDNA metabolic process

CUL4A SMG1 VPS72 MCM8 RRM2B HMGB1 HMGB2 HMGB3 SSRP1 CREBBP YEATS4 PSME4 SMC3 PRIM1 RAD54B XRN1 PRKDC TOP1MT DNA2 TOP3B TOP1 PGBD5 AURKB

2.59e-05108116923GO:0006259
GeneOntologyBiologicalProcessDNA geometric change

MCM8 HMGB1 HMGB2 HMGB3 RAD54B DNA2

7.57e-05861696GO:0032392
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

NAA15 CREBBP NAA25 EP300

8.80e-05291694GO:0031365
GeneOntologyBiologicalProcessDNA repair

CUL4A SMG1 VPS72 MCM8 RRM2B HMGB1 HMGB2 SSRP1 CREBBP YEATS4 PSME4 SMC3 RAD54B PRKDC DNA2 TOP3B

8.89e-0564816916GO:0006281
DomainHMG_boxA_CS

HMGB1 HMGB2 HMGB3

7.15e-0731683IPR017967
DomainHMG_box_2

HMGB1 HMGB2 HMGB3

5.77e-0591683PF09011
DomainTPR-contain_dom

NAA15 TMTC2 NAA25 VPS13A PDCD11 TTC13 PRKDC LONRF2

6.46e-051501688IPR013026
DomainDNA_brk_join_enz

TOP1MT TOP1

8.04e-0521682IPR011010
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

8.04e-0521682IPR014744
DomainTopoI_cat_a/b-sub_euk

TOP1MT TOP1

8.04e-0521682IPR014727
DomainZnF_TAZ

CREBBP EP300

8.04e-0521682SM00551
DomainTopoI

TOP1MT TOP1

8.04e-0521682IPR001631
DomainTopoI_cat_a-hlx-sub_euk

TOP1MT TOP1

8.04e-0521682IPR014711
DomainTopoI_C_dom

TOP1MT TOP1

8.04e-0521682IPR025834
Domain-

TOP1MT TOP1

8.04e-05216821.10.132.10
Domain-

CREBBP EP300

8.04e-05216821.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

8.04e-0521682IPR010303
Domain-

CREBBP EP300

8.04e-05216821.10.1630.10
DomainCreb_binding

CREBBP EP300

8.04e-0521682PF09030
Domainzf-TAZ

CREBBP EP300

8.04e-0521682PF02135
DomainZF_TAZ

CREBBP EP300

8.04e-0521682PS50134
DomainTopoisom_I

TOP1MT TOP1

8.04e-0521682PF01028
DomainTopoI_AS

TOP1MT TOP1

8.04e-0521682IPR018521
DomainDNA_topo_domain1

TOP1MT TOP1

8.04e-0521682IPR013034
DomainTopoI_DNA-bd_mixed-a/b_euk

TOP1MT TOP1

8.04e-0521682IPR013030
DomainKAT11

CREBBP EP300

8.04e-0521682SM01250
Domain-

TOP1MT TOP1

8.04e-05216821.10.10.41
DomainTopoI_euk

TOP1MT TOP1

8.04e-0521682IPR013499
DomainZnf_TAZ

CREBBP EP300

8.04e-0521682IPR000197
Domain-

TOP1MT TOP1

8.04e-05216822.170.11.10
DomainKIX

CREBBP EP300

8.04e-0521682PF02172
DomainTopo_C_assoc

TOP1MT TOP1

8.04e-0521682PF14370
DomainHAT_KAT11

CREBBP EP300

8.04e-0521682PF08214
DomainKIX

CREBBP EP300

8.04e-0521682PS50952
DomainTopoisom_I_N

TOP1MT TOP1

8.04e-0521682PF02919
DomainTOPEUc

TOP1MT TOP1

8.04e-0521682SM00435
DomainCBP_P300_HAT

CREBBP EP300

8.04e-0521682IPR031162
DomainDUF902

CREBBP EP300

8.04e-0521682PF06001
DomainTopoI_cat_euk

TOP1MT TOP1

8.04e-0521682IPR013500
DomainTopoI_DNA-bd_euk

TOP1MT TOP1

8.04e-0521682IPR008336
Domain-

TOP1MT TOP1

8.04e-05216823.90.15.10
Domain-

CREBBP EP300

8.04e-05216821.10.246.20
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

8.04e-0521682IPR013178
DomainKIX_dom

CREBBP EP300

8.04e-0521682IPR003101
DomainCBP_P300_HAT

CREBBP EP300

8.04e-0521682PS51727
DomainTOPOISOMERASE_I_EUK

TOP1MT TOP1

8.04e-0521682PS00176
DomainHMG_BOX_1

HMGB1 HMGB2 HMGB3

8.19e-05101683PS00353
DomainARM-type_fold

SMG1 DOCK9 APOB HEATR1 ODAD2 PSME4 RNPEP CEBPZ PRKDC WDFY3 ARMH3

2.57e-0433916811IPR016024
DomainHEAT_REPEAT

SMG1 HEATR1 ODAD2 PSME4 PRKDC

4.19e-04701685PS50077
DomainNebulin

NRAP NEB

4.77e-0441682PF00880
DomainNEBULIN

NRAP NEB

4.77e-0441682PS51216
DomainNEBU

NRAP NEB

4.77e-0441682SM00227
DomainNebulin

NRAP NEB

4.77e-0441682IPR013998
DomainDUF3338

FRMD4B FRMD4A

4.77e-0441682PF11819
DomainDUF3338

FRMD4B FRMD4A

4.77e-0441682IPR021774
DomainNebulin_repeat

NRAP NEB

4.77e-0441682IPR000900
DomainTPR_REGION

NAA15 TMTC2 NAA25 VPS13A TTC13 PRKDC LONRF2

7.43e-041651687PS50293
DomainTPR

NAA15 TMTC2 NAA25 VPS13A TTC13 PRKDC LONRF2

7.43e-041651687PS50005
DomainHnRNP_R/Q_splicing_fac

RBM47 SYNCRIP

7.90e-0451682IPR006535
DomainFATC

SMG1 PRKDC

7.90e-0451682PF02260
DomainNuc_rcpt_coact

CREBBP EP300

1.18e-0361682IPR009110
DomainFAT

SMG1 PRKDC

1.18e-0361682PS51189
DomainFATC

SMG1 PRKDC

1.18e-0361682PS51190
DomainFATC_dom

SMG1 PRKDC

1.18e-0361682IPR003152
DomainPIK_FAT

SMG1 PRKDC

1.18e-0361682IPR014009
DomainFATC

SMG1 PRKDC

1.18e-0361682SM01343
DomainTPR-like_helical_dom

SAMD9 NAA15 TMTC2 NAA25 PDCD11 TTC13 PRKDC LONRF2

1.25e-032331688IPR011990
DomainHMG_box

HMGB1 HMGB2 HMGB3 SSRP1

1.31e-03531684PF00505
DomainHMG_BOX_2

HMGB1 HMGB2 HMGB3 SSRP1

1.41e-03541684PS50118
DomainHMG

HMGB1 HMGB2 HMGB3 SSRP1

1.41e-03541684SM00398
Domain-

HMGB1 HMGB2 HMGB3 SSRP1

1.51e-035516841.10.30.10
DomainHMG_box_dom

HMGB1 HMGB2 HMGB3 SSRP1

2.79e-03651684IPR009071
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 PDE6A ANK2 HMGB1 HMGB2 HMGB3 SPG11 RGS11 APOB VPS36 HEATR1 SSRP1 NEB PLA2G4D MECP2 CHRNA1 RINT1 CEBPZ VPS13A XRN1 PRKDC TOP1MT TASOR MNDA TOP3B TOP1 DOP1A SYNCRIP

9.13e-1014421752835575683
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CASP8AP2 SLC4A7 NAA15 ANK2 UACA CYP51A1 SPG11 SEC22B HEATR1 DNAJC22 SSRP1 MRPL39 RINT1 TRMT10C CCDC88A SLC25A40 SNX6 CEBPZ MACO1 VPS13A PDCD11 TTC13 DNA2 PLOD2 TOP3B SYNCRIP

3.26e-0814871752633957083
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

SLC4A7 NAA15 HMGB1 RNF213 SEC22B HEATR1 IDH2 SSRP1 MRPL39 RINT1 IGF2BP1 TRMT10C MIGA2 SLC25A40 SNX6 MACO1 VPS13A PDCD11 TTC13 HADH TOP3B TOP1 PGBD5 MOV10 SYNCRIP CHP1

3.67e-0814961752632877691
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CUL4A FLYWCH1 UACA MATN2 APOB HEATR1 SSRP1 MYO5C NEDD9 S100A8 IGF2BP1 SMC3 CEBPZ PDCD11 PRKDC TOP1MT TOP1 MOV10 SYNCRIP AURKB

7.73e-089491752036574265
Pubmed

Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.

HMGB1 HMGB2 HMGB3

1.25e-073175331621076
Pubmed

High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro.

HMGB1 HMGB2 PRKDC

1.25e-07317539722660
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SMG1 HMGB1 HMGB2 HMGB3 HEATR1 SSRP1 IGF2BP1 TRMT10C CEBPZ XRN1 PDCD11 PRKDC RBM47 HNRNPLL TOP3B TOP1 MOV10 SYNCRIP

1.57e-078071751822681889
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FLYWCH1 UACA RNF213 IGDCC4 OGFOD1 DNAH5 MOV10

8.36e-07101175710997877
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

UACA RNF213 SEC22B MCM3AP CTDP1 EP300 CHP1

1.02e-06104175731240132
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

CUL4A UACA RNF213 HEATR1 SSRP1 SNX6 CEBPZ MCM3AP XRN1 PDCD11 TASOR

1.09e-063321751125693804
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 SAMD9 NAA15 MCM8 RINT1 CCDC88A PSME4 RAD54B PRSS21 XRN1 OGFOD1 DNA2 RBM47 TASOR IQGAP3

1.18e-066501751538777146
Pubmed

CRL4-DCAF12 Ubiquitin Ligase Controls MOV10 RNA Helicase during Spermatogenesis and T Cell Activation.

CUL4A IL17RB MOV10

1.24e-065175334065512
Pubmed

Distinct embryonic expression and localization of CBP and p300 histone acetyltransferases at the mouse alphaA-crystallin locus in lens.

CREBBP CRYAA EP300

1.24e-065175317467007
Pubmed

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses.

HMGB1 HMGB2 HMGB3

1.24e-065175319890330
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SEC22B HEATR1 IDH2 SSRP1 IGF2BP1 SMC3 CEBPZ PDCD11 PRKDC DNAH5 HNRNPLL TOP1 IQGAP3 MOV10 AURKB

3.12e-067041751529955894
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SMG1 CASP8AP2 SPAST FLYWCH1 HECTD4 SPG11 FRMD4B CCDC88A PSME4 PDCD11 DNA2 CRAMP1 IGSF3

3.15e-065291751314621295
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CUL4A HTRA1 VPS72 MCM8 UACA GPT QTRT2 RNF213 SSRP1 CREBBP MECP2 YEATS4 MCM3AP XRN1 WDFY3 DNA2 TOP1 EP300 AURKB

3.95e-0611161751931753913
Pubmed

A unique SUMO-2-interacting motif within LANA is essential for KSHV latency.

CREBBP PRKDC EP300

4.32e-067175324278015
Pubmed

In vitro acetylation of HMGB-1 and -2 proteins by CBP: the role of the acidic tail.

HMGB1 HMGB2 CREBBP

4.32e-067175315005629
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

PPP3CC SMC3 XRN1 PRKDC TOP1 MOV10

5.37e-0687175617148452
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SAMD9 NAA15 UACA HMGB1 HMGB2 HEATR1 SSRP1 MECP2 MRPL39 TRMT10C SMC3 CEBPZ PRIM1 PDCD11 PRKDC TOP1 IQGAP3 MOV10 SYNCRIP AURKB

5.92e-0612571752036526897
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

HEATR1 SSRP1 IGF2BP1 SMC3 CEBPZ XRN1 PDCD11 PRKDC TASOR TOP3B TOP1 IQGAP3 MOV10 SYNCRIP AURKB

7.67e-067591751535915203
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

HMGB2 IDH2 SSRP1 IGF2BP1 TRMT10C PRKDC TOP1 SYNCRIP AURKB CHP1

8.23e-063341751030425250
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

NAA15 JMJD4 QTRT2 SEC22B HEATR1 MRPL39 IGF2BP1 TRMT10C SNX6 SMC3 MACO1 XRN1 TTC13 PRKDC HNRNPLL ABTB2 SYNCRIP

9.50e-069741751728675297
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HMGB1 SEC22B APOB HEATR1 IDH2 SSRP1 S100A8 IGF2BP1 TRMT10C RNPEP SMC3 CEBPZ PRIM1 PDCD11 PRKDC DNAH5 HNRNPLL TOP1 IQGAP3 TMEM117 SYNCRIP

1.09e-0514251752130948266
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

HMGB1 HEATR1 SSRP1 MECP2 IGF2BP1 SMC3 VPS13A PDCD11 TOP1 MOV10 SYNCRIP

1.27e-054301751138172120
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

SMG1 UACA HMGB1 QTRT2 RNF213 SEC22B HEATR1 IDH2 SSRP1 RINT1 IGF2BP1 TRMT10C CEBPZ MACO1 COMMD10 PDCD11 PRKDC PLOD2 MOV10 SYNCRIP CHP1

1.28e-0514401752130833792
Pubmed

The functions of the HIV1 protein Vpr and its action through the DCAF1.DDB1.Cullin4 ubiquitin ligase.

CUL4A CREBBP EP300

1.46e-0510175320347598
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CUL4A CASP8AP2 ANXA4 HMGB1 RNF213 HMGB2 HMGB3 SSRP1 CREBBP RNPEP SMC3 PRIM1 PRKDC HNRNPLL TOP1 EP300 AURKB

1.59e-0510141751732416067
Pubmed

Interaction proteomics of the HMGA chromatin architectural factors.

HMGB1 HMGB2 HMGB3 SYNCRIP

2.00e-0532175418850631
Pubmed

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

CREBBP CRYAA EP300

2.01e-0511175324038357
Pubmed

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

HEATR1 SPATA2 CREBBP SLC25A40 SP140L VPS13A PRKDC ARMH3 CRAMP1 SYNCRIP AURKB

2.23e-054571751132968282
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

UACA DOCK9 HMGB1 HMGB2 HMGB3 SSRP1 EFHB HMGB1P1 MRPL39 S100A8 IGF2BP1 TRMT10C SMC3 PDCD11 PRKDC TOP1 MOV10 SYNCRIP

2.29e-0511531751829845934
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

2.52e-052175227881875
Pubmed

Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.

TOP1MT TOP1

2.52e-052175222911747
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

2.52e-052175234845315
Pubmed

Cloning and analysis of an HMG gene from the lamprey Lampetra fluviatilis: gene duplication in vertebrate evolution.

HMGB1 HMGB2

2.52e-05217529016958
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

2.52e-052175219729597
Pubmed

A series of Greek children with pure hereditary spastic paraplegia: clinical features and genetic findings.

SPAST GPT

2.52e-052175227260292
Pubmed

Hmg4, a new member of the Hmg1/2 gene family.

HMGB1 HMGB3

2.52e-05217529598312
Pubmed

CYP2C9 and ABCG2 polymorphisms as risk factors for developing adverse drug reactions in renal transplant patients taking fluvastatin: a case-control study.

CYP2C9 ABCG2

2.52e-052175224024895
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

2.52e-052175239287984
Pubmed

Evidence for a shared structural role for HMG1 and linker histones B4 and H1 in organizing chromatin.

HMGB1 HMGB2

2.52e-05217528599938
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

2.52e-052175220717166
Pubmed

DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.

PRKDC TOP1

2.52e-052175226578593
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

2.52e-052175225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

2.52e-052175211559821
Pubmed

P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation.

IDH2 CREBBP

2.52e-052175230526058
Pubmed

The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma.

HMGB1 HMGB2

2.52e-052175225060178
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

2.52e-052175232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

2.52e-052175219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

2.52e-052175224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

2.52e-052175221847097
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

2.52e-052175234813504
Pubmed

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.

TOP1MT TOP1

2.52e-052175226305952
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

2.52e-052175220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

2.52e-052175224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

2.52e-052175237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

2.52e-052175211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

2.52e-052175210918613
Pubmed

Mitochondrial topoisomerase I sites in the regulatory D-loop region of mitochondrial DNA.

TOP1MT TOP1

2.52e-052175218826252
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

2.52e-052175235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

2.52e-052175231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

2.52e-052175230888860
Pubmed

cDNA sequence and structure of a trout HMG-2 gene. Evidence for a trout-specific 3'-untranslated region.

HMGB1 HMGB2

2.52e-05217527607539
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

2.52e-052175227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

2.52e-052175219272189
Pubmed

HMGB proteins and arthritis.

HMGB1 HMGB2

2.52e-052175228916968
Pubmed

Recent integrations of mammalian Hmg retropseudogenes.

HMGB1 HMGB2

2.52e-052175217406091
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

2.52e-052175232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

2.52e-052175230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

2.52e-052175221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

2.52e-05217529811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

2.52e-052175224089570
Pubmed

SNARE protein SEC22B regulates early embryonic development.

SEC22B COMMD10

2.52e-052175231391476
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

2.52e-052175215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

2.52e-052175239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

2.52e-052175222303793
Pubmed

Interactions of HMGB Proteins with the Genome and the Impact on Disease.

HMGB1 HMGB2

2.52e-052175234680084
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

2.52e-052175234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

2.52e-052175234019788
Pubmed

The influence of the major histocompatibility complex on development of autoimmune diabetes in RIP-B7.1 mice.

CD80 PRKDC

2.52e-052175215983204
Pubmed

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.

ODAD2 DNAH5

2.52e-052175224203976
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

2.52e-052175215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

2.52e-052175229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

2.52e-052175224551300
Pubmed

Progressive Changes in a Distributed Neural Circuit Underlie Breathing Abnormalities in Mice Lacking MeCP2.

MECP2 HOXB1

2.52e-052175227194336
Pubmed

Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines.

ABCG2 TOP1

2.52e-052175226801902
Pubmed

Association of HMGB1 and HMGB2 genetic polymorphisms with lung cancer chemotherapy response.

HMGB1 HMGB2

2.52e-052175224684392
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

2.52e-052175233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

2.52e-05217529018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

2.52e-052175224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

2.52e-052175230135524
Pubmed

DNA-dependent protein kinase interacts functionally with the RNA polymerase II complex recruited at the human immunodeficiency virus (HIV) long terminal repeat and plays an important role in HIV gene expression.

CTDP1 PRKDC

2.52e-052175221450944
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

2.52e-052175216596650
Pubmed

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures.

HMGB1 HMGB2

2.52e-05217528339930
Pubmed

Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.

HMGB1 HMGB2

2.52e-05217529600082
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

2.52e-052175229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

2.52e-052175210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

2.52e-052175227380996
InteractionCTDP1 interactions

UACA HMGB1 RNF213 SEC22B MCM3AP CTDP1 PRKDC TOP3B EP300 AURKB CHP1

1.92e-0620717411int:CTDP1
InteractionIWS1 interactions

HMGB1 SSRP1 MECP2 CCDC88A CTDP1 TOP1 EP300 MOV10

7.56e-061161748int:IWS1
InteractionHMGB3 interactions

HMGB1 HMGB2 HMGB3 SSRP1 MECP2 TOP1 MOV10

1.50e-05921747int:HMGB3
GeneFamilyTopoisomerases

TOP1MT TOP3B TOP1

5.76e-06612131050
GeneFamilyCanonical high mobility group

HMGB1 HMGB2 HMGB3

4.64e-05111213511
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

SLC4A7 MECP2 FBXO38 RINT1 PSME4 PGAP1 MCM3AP VPS13A HERC3 EP300 DOP1A

1.05e-0720017411M9889
CoexpressionFISCHER_DREAM_TARGETS

CASP8AP2 NAA15 MCM8 UACA CYP51A1 HMGB1 HMGB2 HMGB3 HEATR1 SSRP1 YEATS4 SLC25A40 SMC3 PRIM1 RAD54B MTBP PRKDC HADH DNA2 TOP1 IQGAP3 SYNCRIP AURKB

1.28e-0796917423M149
CoexpressionFEVR_CTNNB1_TARGETS_DN

CASP8AP2 CYP2C9 SLC4A7 NAA15 MATN2 HMGB1 HMGB2 HMGB3 SSRP1 RWDD3 SLC13A1 SMC3 PRIM1 MTBP HADH AURKB

1.00e-0655517416M2343
CoexpressionONKEN_UVEAL_MELANOMA_UP

CASP8AP2 HTRA1 SPAST ANK2 SGK1 ANXA4 DOCK9 CYP51A1 HMGB2 IDH2 FRMD4B PSME4 PGAP1 MCM3AP RAD54B PRKDC ABTB2 SYNCRIP

5.76e-0679017418M12490
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CASP8AP2 NAA15 MATN2 RRM2B HMGB1 SPG11 RINT1 TRMT10C CCDC88A YEATS4 CSGALNACT2 SMC3 CEBPZ RAD54B TASOR SLC16A7

8.45e-0665617416M18979
CoexpressionNUYTTEN_EZH2_TARGETS_DN

SLC4A7 SPAST MCM8 RRM2B JMJD4 HMGB1 HMGB2 HMGB3 HEATR1 DNAJC22 SSRP1 SMC3 PRIM1 RAD54B MTBP TOP1MT DNA2 RBM47 IQGAP3 AURKB

1.62e-05102317420M17122
CoexpressionKAUFFMANN_DNA_REPAIR_GENES

RRM2B HMGB1 HMGB2 SSRP1 SMC3 RAD54B PRKDC TOP3B TOP1

2.46e-052301749M11563
CoexpressionBUSSLINGER_DUODENAL_LATE_IMMATURE_ENTEROCYTES

CIDEB CYP2C9 SLC4A7 ANXA4 APOB MEP1A ABCG2 RBM47

2.52e-051771748M40028
CoexpressionISHIDA_E2F_TARGETS

HMGB2 HMGB3 PRIM1 DNA2 AURKB

2.70e-05531745M1945
CoexpressionGCNP_SHH_UP_LATE.V1_UP

CUL4A NAA15 IDH2 SERPINB9 PSME4 CD80 AURKB CHP1

2.96e-051811748M2641
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP

RNF213 NEB FRMD4B YEATS4 PRIM1 PLOD2 HNRNPLL AURKB

3.20e-051831748M2993
CoexpressionISHIDA_E2F_TARGETS

HMGB2 HMGB3 PRIM1 DNA2 AURKB

3.24e-05551745MM1264
CoexpressionGSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP

SMG1 NAT8L RRM2B DNAJC22 SSRP1 NEB PRKDC RSPH9

6.00e-052001748M6044
CoexpressionGSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP

UACA RNF213 IL18R1 NRP2 HOXB1 SERPINB9 ABTB2 MCOLN3

6.00e-052001748M6256
CoexpressionGSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_UP

NAA15 ANXA4 FRMD4B SERPINB9 PPP3CC CD80 DNA2 CRAMP1

6.00e-052001748M9261
CoexpressionGOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP

ANXA4 HMGB3 S100A8 SERPINB9 PRIM1 DNA2 IQGAP3 AURKB

6.00e-052001748M3041
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

CIDEB CYP2C9 SLC4A7 UACA SGK1 APOB MIGA2 ABCG2 INPP5J

6.19e-052591749M40029
CoexpressionJOHNSTONE_PARVB_TARGETS_2_DN

DOCK9 SEC22B SLC25A40 SMC3 VPS13A XRN1 HADH SLC16A7 HNRNPLL SYNCRIP

1.07e-0434417410M2239
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP

VPS72 HEATR1 FRMD4A SLC13A1 OGFOD1 ZNF749 HABP2 TOP3B PGBD5 IL17RB

1.21e-0434917410M283
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

SLC4A7 TMTC2 DNAH14 RBM47 DNAH5 PLOD2 SLC16A7

1.41e-041691747M39230
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

CIDEB SMG1 SAMD9 SLC4A7 DOCK9 HECTD4 HMGB1 RNF213 SPG11 IL18R1 CREBBP MECP2 NEDD9 SERPINB9 CCDC88A PPP3CC CSGALNACT2 SMC3 XRN1 TASOR SLC16A7 HNRNPLL EP300

1.45e-04149217423M40023
CoexpressionTIEN_INTESTINE_PROBIOTICS_6HR_DN

SPAST SGK1 DOCK9 SPATA2 YEATS4 PSME4 SNX6

1.46e-041701747M19990
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 FBLN7 MCM8 HMGB1 PRIM1 RAD54B MTBP PRKDC DNA2

7.91e-081951749cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HMGB1 HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 HADH AURKB

9.41e-08199174999778178e3ec121802db938db8c5475d19b43fec
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 FBLN7 MCM8 RAD54B PRKDC DNA2 IQGAP3 AURKB

5.42e-07179174888d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB NAT8L HTRA1 APOB SLC13A1 HABP2 ABCG2 THNSL2

6.67e-0718417483d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SAMD9 RNF213 SERPINB9 CD80 XRN1 HNRNPLL ABTB2 MOV10

9.56e-07193174822455801194bd8c73c5c397f5eac4f723429c383
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 FBLN7 MCM8 HMGB1 PRIM1 RAD54B MTBP DNA2

1.03e-06195174856d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 FBLN7 MCM8 PRIM1 RAD54B MTBP PRKDC DNA2

1.07e-061961748df366d76ea55f49e349d622effa57c1535df8400
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

HMGB2 HMGB3 IDH2 SSRP1 MRPL39 RNPEP DNA2 AURKB

1.07e-06196174836ed1918f70b6f5760bb088b15ce422998055cc7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MCF2L2 OVCH1 FRMD4A CCDC88A ABCG2 DNA2 IQGAP3 AURKB

1.12e-061971748d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCell10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HMGB1 HMGB2 HMGB3 YEATS4 PPP3CC SMC3 HADH AURKB

1.20e-0619917488daf945fc93169b0a4fa3ef9f4a87eedd52e314a
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

HMGB1 HMGB2 HMGB3 SMC3 PRIM1 PRKDC HADH AURKB

1.25e-062001748548a0f486ab8745da107f2815914dbf873a6e3c8
ToppCellC_02|World / shred on cell type and cluster

CIDEB SLC4A7 SGK1 MATN2 APOB MEP1A ABCG2

3.98e-061651747a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

HMGB3 S100A8 CCDC88A WDFY3 MNDA IQGAP3 AURKB

5.44e-061731747783b8fa08b9d8f597f251793eae164151662f1f9
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMGB2 SMC3 PRIM1 RAD54B MTBP CRAMP1 AURKB

5.65e-061741747c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ANK2 MCM8 HMGB3 MTBP ABCG2 IQGAP3 AURKB

5.87e-061751747bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

SAMD9 SGK1 RNF213 FRMD4B PGAP1 XRN1 LONRF2

6.56e-061781747ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SAMD9 RNF213 NAA25 PGAP1 XRN1 TOP1 MOV10

6.80e-061791747af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 HTRA1 MCM8 HMGB2 PRIM1 RAD54B IQGAP3

6.80e-0617917479dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HMGB1 HMGB2 HMGB3 NMU FBXL5 IQGAP3 AURKB

6.80e-0617917476718cadcc2d3b64717ed84244ef1242d392662dc
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PDE6A S100A8 CSGALNACT2 GOLGA1 EP300

6.99e-06681745f1cbc6d72489272c1eb6200f64b8b6444719acda
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMG1 CCDC88A PGAP1 XRN1 MNDA RSPH9 EP300

7.58e-061821747f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 PHYHIP IDH2 KCNJ1 SLC16A7 TOP3B INPP5J

7.86e-061831747f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L HTRA1 APOB SLC13A1 HABP2 ABCG2 THNSL2

8.14e-061841747c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L HTRA1 APOB SLC13A1 HABP2 ABCG2 THNSL2

8.14e-0618417477c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L HTRA1 APOB SLC13A1 HABP2 ABCG2 THNSL2

8.14e-06184174745577ff91c3b2b303acd97239dde2463ea7a429c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 PHYHIP IDH2 KCNJ1 SLC16A7 TOP3B INPP5J

8.14e-0618417478939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|bone_marrow / Manually curated celltypes from each tissue

HMGB2 HMGB3 S100A8 CCDC88A RBM47 MNDA AURKB

8.74e-061861747e82d5e7a976b9cfa2b4640c7a7cd1cfea19c4806
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

SAMD9 RNF213 NAA25 PGAP1 XRN1 TOP1 MOV10

9.37e-0618817476f8946d4710f6e32c937213f99b790b098b8819c
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGS11 ODAD2 CFAP100 PPP1R36 DNAH5 RSPH9 RSPH10B

9.70e-061891747b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGS11 ODAD2 CFAP100 PPP1R36 DNAH5 RSPH9 RSPH10B

9.70e-0618917474e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HMGB1 HMGB2 HMGB3 FBXL5 CCDC88A IQGAP3 AURKB

1.00e-051901747cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RRM2B FBXL5 SLC25A40 RABGEF1 HERC3 DNA2 IQGAP3

1.00e-0519017473f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

CYP51A1 RNF213 HEATR1 ANKRD36C IL18R1 PRKDC DNA2

1.04e-0519117479454f642c3621370fa23640b631301346b300950
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAT8L SLC4A7 ANK2 IDH2 NEB KCNJ1 SLC16A7

1.07e-051921747ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RRM2B FBXL5 SLC25A40 RABGEF1 HERC3 DNA2 IQGAP3

1.07e-051921747c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SLC4A7 MCF2L2 RNF213 ANKRD36C RSPH10B2 VPS13A

1.11e-0519317479337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 PHYHIP IDH2 KCNJ1 PGAP1 SLC16A7 INPP5J

1.11e-051931747fa8bcf2a5ab7b08fae98a1466a936995142b4309
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMGB1 HMGB2 HMGB3 PRIM1 RAD54B IQGAP3 AURKB

1.15e-0519417473a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CASP8AP2 FBLN7 MCM8 PRIM1 RAD54B MTBP DNA2

1.19e-051951747b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SAMD9 RNF213 NAA25 XRN1 MNDA MOV10 DOP1A

1.19e-051951747b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellMonocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FRMD4B NRP2 S100A8 FRMD4A CCDC88A RBM47 MNDA

1.23e-051961747ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCell3'-Child09-12|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SAMD9 SGK1 RNF213 APOB MEP1A SLC13A1 ABCG2

1.23e-0519617471bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCellMonocytes-IL1B+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SGK1 FRMD4B NRP2 FRMD4A CCDC88A RBM47 MNDA

1.23e-0519617477bc0735d324ac5a1661434cda4116ddd58296730
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 SLC4A7 MCF2L2 RNF213 ANKRD36C VPS13A XRN1

1.27e-05197174757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellASK452-Immune-Macrophages|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SGK1 S100A8 SERPINB9 CCDC88A RBM47 MNDA TOP1

1.31e-05198174792293d389bf7d76ba057613e573c2595676ded85
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK2 MATN2 NEB CHRNA1 IGDCC4 GSG1L IGSF3

1.31e-05198174755e583321f60c95898d93cd0d2615c6692db52ec
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

SAMD9 RNF213 IDH2 SERPINB9 PGAP1 XRN1 DOP1A

1.31e-051981747ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAT8L SGK1 CHRNA1 MEP1A FRMD4A CCDC88A MNDA

1.31e-0519817470b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

HMGB2 HMGB3 S100A8 CCDC88A MNDA IQGAP3 AURKB

1.31e-0519817475c92687b853ebb00960adbef6552f9d460bc6886
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HMGB1 HMGB2 IDH2 PPP3CC SMC3 HADH AURKB

1.35e-0519917475478b78349b5d8d57f30bb650dcbd5fdb84283d6
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMGB1 HMGB2 PRIM1 MNDA IQGAP3 IL17RB AURKB

1.35e-05199174713ff6c26ebcc663ef8e5559ab9be99dab848abe7
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-0519917474394dcd1809f49e9bada8f5e115d5123356eae3e
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-051991747c0ea391bb347b99b94b5d7f02612ede938986745
ToppCelltumor_Lung-T/NK_cells-Undetermined|tumor_Lung / Location, Cell class and cell subclass

HMGB1 HMGB2 HMGB3 IDH2 YEATS4 SMC3 AURKB

1.35e-0519917472e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCell10x5'-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

HMGB1 HMGB2 HMGB3 ABCG2 IQGAP3 IL17RB AURKB

1.35e-051991747dee1cf8ee850a2bd57349418a9bcc0948fe9ac9e
ToppCellnormal_Lung-T/NK_cells-Undetermined|T/NK_cells / Location, Cell class and cell subclass

HMGB1 HMGB2 HMGB3 IDH2 PRIM1 IQGAP3 AURKB

1.35e-0519917474142d5b1b20212508f95841fdac4efb7655616cb
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-05199174796af1f289552f38f2dfa181192eb3276f4c7d70b
ToppCellremission-T/NK_proliferative|World / disease stage, cell group and cell class

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-051991747f305f3a454b7d2170429bad087480ccccca19acd
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEC22B FRMD4B FBXL5 S100A8 CSGALNACT2 RBM47 MNDA

1.35e-05199174786f2857ce60fbe59375411373ff49c684fd66ad0
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBLN7 MCM8 HMGB2 NMU DNA2 IQGAP3 AURKB

1.35e-0519917471d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Convalescent / Disease group, lineage and cell class

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-051991747893b78c661c529db07a5fcc3124d9b3d0f270fa5
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

SAMD9 SLC4A7 RNF213 ANKRD36C SP140L CEBPZ XRN1

1.35e-051991747952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-0519917475b18e18ddbf4bd53aa0d574d23092cb96da7f400
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-0519917476df65f4c2f9a125e0c7c4f597fefc05a97fc8831
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-Other_T|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.35e-051991747cb229aa3eb7b1cc47e76711b8fc18fce88a5cf08
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NAT8L MATN2 MCF2L2 OGFOD1 PGBD5 IL17RB AURKB

1.35e-0519917472b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCellmyeloid-pro-cDC|myeloid / Lineage and Cell class

IDH2 SSRP1 YEATS4 SMC3 PRIM1 HADH AURKB

1.40e-0520017474aa2308eeb94e0bdff4e02eb9e45ba8837ae14bf
ToppCellmild-HLA-DR-_S100A+_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HTRA1 SGK1 S100A8 CCDC88A RBM47 MNDA CHP1

1.40e-0520017476dd89835a9f7bebb4849cff8eecb82caf6e1acbf
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

MCM8 HMGB1 HMGB2 HMGB3 IDH2 SMC3 AURKB

1.40e-0520017474923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGK1 CHRNA1 MEP1A FRMD4A CCDC88A RBM47 MNDA

1.40e-05200174778d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HMGB1 HMGB2 CCDC88A PRIM1 MNDA IQGAP3 AURKB

1.40e-0520017475e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

MCM8 HMGB1 HMGB2 HMGB3 IDH2 SMC3 AURKB

1.40e-052001747dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Convalescent / Disease, condition lineage and cell class

HMGB2 HMGB3 IDH2 SSRP1 YEATS4 SMC3 AURKB

1.40e-05200174700538c4cbab5da00b3a366717d38a3ba5cfe3f65
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

MCM8 HMGB1 HMGB2 SSRP1 SMC3 PRKDC AURKB

1.40e-0520017477e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells|1m / Sample Type, Dataset, Time_group, and Cell type.

HMGB1 HMGB2 HMGB3 NMU SMC3 PRIM1 AURKB

1.40e-05200174713636463e44a99cd886926340bfb35880f95cca6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Stem_cells-Neuroepithelial_cell|1m / Sample Type, Dataset, Time_group, and Cell type.

HMGB1 HMGB2 HMGB3 NMU SMC3 PRIM1 AURKB

1.40e-0520017472a3874634cc4357a64ef9fd4a6bbdfd84236ebac
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

MCM8 HMGB1 HMGB2 SSRP1 SMC3 PRKDC AURKB

1.40e-0520017479775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|343B / Donor, Lineage, Cell class and subclass (all cells)

MCM8 PSME4 TTC13 IL17RB AURKB GRAP

1.40e-0513317468ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
ToppCellCOVID-19_Mild-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

GLB1L3 TMPRSS12 RGS11 RSPH10B2 FRMD4A GABRA2

1.88e-051401746b1429028c52f84127b894b93b55961badcd5246f
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GLB1L3 TMPRSS12 RGS11 RSPH10B2 FRMD4A GABRA2

2.11e-0514317469836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GLB1L3 TMPRSS12 RGS11 RSPH10B2 FRMD4A GABRA2

2.11e-0514317464622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

MATN2 METTL24 MTBP WDFY3 GOLGA1 GRAP

2.47e-0514717464ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L MATN2 FBXL5 S100A8 ARMH3 ABTB2

2.57e-051481746b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L MATN2 FBXL5 S100A8 ARMH3 ABTB2

2.57e-051481746ba277c898678dd36f8dc1d681301c71901b89055
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

HMGB1 HMGB2 HMGB3 IDH2 SSRP1 PRIM1

2.67e-051491746e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBLN7 HMGB3 MCOLN3 RSPH10B IL17RB AURKB

3.45e-051561746955547dfeb1b1ad4957b4338701055726b22619f
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAT8L HMGB2 S100A8 MNDA IQGAP3 AURKB

3.58e-051571746904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMGB2 NEB KCNJ1 PRIM1 RAD54B HERC3

3.98e-0516017465cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEB NAP1L6P NMU RAD54B IQGAP3 AURKB

4.12e-0516117462165897924c790fec43502283f1df221c56c1e9f
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

IL18R1 MYO5C S100A8 WDFY3 MNDA RSPH9

4.12e-05161174698c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATN2 CFAP100 HOXB1 GSG1L INPP5J TMEM117

4.26e-051621746b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellfacs-SCAT-Fat-18m-Epithelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB GPT DNAJC22 MEP1A INPP5J TMEM117

4.26e-051621746341fa357ad7bdbef30864e8062f161e60185ffc9
ToppCellfacs-SCAT-Fat-18m-Epithelial-epithelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB GPT DNAJC22 MEP1A INPP5J TMEM117

4.26e-0516217467215f6eb2b65dea455e2eec722a9c38e6958b120
ToppCellfacs-SCAT-Fat-18m-Epithelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB GPT DNAJC22 MEP1A INPP5J TMEM117

4.26e-0516217467fa93efa2039d68a4e8214fa143bcd3368349a2d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTRA1 SGK1 MCF2L2 FRMD4A SERPINB9 ABCG2

4.41e-051631746a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPT LONRF2 DNAH5 RSPH9 IQGAP3 AURKB

4.56e-0516417464307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPT LONRF2 DNAH5 RSPH9 IQGAP3 AURKB

4.56e-0516417461d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB GPT APOB MEP1A ABCG2 CHP1

4.72e-051651746ce79d217df88035457cd58f679e72dd98722ae22
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIDEB GPT MEP1A ABCG2 INPP5J CHP1

4.88e-05166174622b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

S100A8 FBXO38 CXorf58 MNDA ABTB2 MOV10

5.05e-051671746820472887f43b42ae7e44513ca3d5465fb4f71a7
DrugStallimycin

HMGB1 HMGB2 HMGB3 SSRP1 SMC3 PRIM1 TOP1MT TOP3B TOP1

1.05e-08801749CID000003115
DrugAC1L36FJ

HMGB1 HMGB2 HMGB3 SSRP1 PRKDC

4.54e-07211745CID000083911
DrugEdotecarinum

ABCG2 TOP1MT TOP3B TOP1

6.68e-07101744CID000151078
DrugBNP1350

ABCG2 TOP1MT TOP3B TOP1

1.56e-06121744CID000148202
DrugC20H16N2O5

HMGB1 HMGB2 TOP1MT TOP3B TOP1

1.73e-06271745CID000119122
DrugVincristine

CUL4A CYP2C9 SLC4A7 VPS72 SGK1 MATN2 HECTD4 HMGB1 RNF213 CREBBP MRPL39 S100A8 NAA25 PSME4 SP140L CD80 PRIM1 VPS13A ABCG2 PRKDC DNA2 ABTB2 IL17RB SYNCRIP AURKB

3.81e-06118217425ctd:D014750
DrugNSC 314622

TOP1MT TOP3B TOP1

4.34e-0651743CID000329826
Drug4-demethoxy-11-deoxy-4'-epi-daunorubicin

TOP1MT TOP3B TOP1

4.34e-0651743CID000158476
Drug4-demethyl-6-O-methyldoxorubicin

TOP1MT TOP3B TOP1

4.34e-0651743CID000126902
Drug2-bromo-dATP

TOP1MT TOP3B TOP1

4.34e-0651743CID000129443
DrugNSC622082

TOP1MT TOP3B TOP1

4.34e-0651743CID000494392
Drugeupolauridine

TOP1MT TOP3B TOP1

4.34e-0651743CID000072486
Drugd(GpG

HMGB1 HMGB2 HMGB3 SSRP1 PRKDC

6.63e-06351745CID000161113
Drugintoplicine

TOP1MT TOP3B TOP1

8.63e-0661743CID000065954
Druggalbacin

GPT TOP1MT TOP1

8.63e-0661743CID000234441
DrugUCE6

TOP1MT TOP3B TOP1

8.63e-0661743CID000127735
Drugethoxidine

TOP1MT TOP3B TOP1

8.63e-0661743CID000476777
DrugBE-10988

TOP1MT TOP3B TOP1

8.63e-0661743CID000126200
Drugsaintopin

TOP1MT TOP3B TOP1

8.63e-0661743CID000131350
Drugazalanstat

CYP2C9 CYP51A1 APOB CRAMP1

9.27e-06181744CID000060876
Drug10-hydroxycamptothecin

PDE6A ABCG2 TOP1MT TOP3B TOP1

1.30e-05401745CID000097226
DrugDemecolcine

CUL4A SLC4A7 VPS72 SGK1 RRM2B HECTD4 PSME4 SP140L SMC3 CD80 MACO1 PRIM1 PGAP1 VPS13A PRKDC DNA2 ABTB2 IL17RB SYNCRIP AURKB

1.35e-0587817420ctd:D003703
Drugnitidine

TOP1MT TOP3B TOP1

1.50e-0571743CID000004501
DrugD01432

ABCG2 TOP1MT TOP1

1.50e-0571743CID011954228
DrugAC1L4GCF

TOP1MT TOP3B TOP1

1.50e-0571743CID000156514
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; HL60; HG-U133A

CUL4A FBXO38 RINT1 CCDC88A SMC3 MCM3AP PRKDC HADH DOP1A

2.16e-0519717491386_DN
DrugZINC03993519

ABCG2 TOP1MT TOP3B TOP1

2.16e-05221744CID006440178
Drug9-HME

TOP1MT TOP3B TOP1

2.39e-0581743CID003034753
DrugNSC-294410

TOP1MT TOP3B TOP1

2.39e-0581743CID000457914
DrugdPMC

APOB RNPEP SMC3

3.56e-0591743CID000125296
Drugardisin

TOP1MT TOP3B TOP1

3.56e-0591743CID000417291
DrugIST-622

TOP1MT TOP3B TOP1

3.56e-0591743CID003081749
Drugo-AMSA

TOP1MT TOP3B TOP1

3.56e-0591743CID000107747
Drugethidium bromide

CHRNA1 SLC13A1 SMC3 TOP1MT TOP3B TOP1

4.85e-05851746CID000003624
DrugdFdCTP

RRM2B PRIM1 ABCG2 TOP1

5.04e-05271744CID000130659
DrugAC1MZ4R5

TOP1MT TOP3B TOP1

5.06e-05101743CID003842392
Drugdiospyrin

TOP1MT TOP3B TOP1

5.06e-05101743CID000308140
DrugIrinotecan

TOP1MT TOP1

5.81e-0521742DB00762
DrugTopotecan

TOP1MT TOP1

5.81e-0521742DB01030
DrugAC-759

CYP2C9 SLC4A7 PRIM1 TOP1MT TOP3B TOP1

5.90e-05881746CID000005396
DrugMagnetite Nanoparticles

SMG1 CASP8AP2 SLC4A7 RRM2B CYP51A1 RNF213 HMGB2 CREBBP MECP2 FRMD4B NRP2 NEDD9 S100A8 IGF2BP1 SERPINB9 CCDC88A CSGALNACT2 CD80 MNDA ABTB2 MOV10 IGSF3 SYNCRIP GRAP

6.24e-05131017424ctd:D058185
DrugAC1L1COZ

NAA15 IDH2 CREBBP MCM3AP VPS13A EP300

6.69e-05901746CID000001996
Drug9-aminocamptothecin

ABCG2 TOP1MT TOP3B TOP1

6.74e-05291744CID000072402
Drugmerbarone

PRIM1 TOP1MT TOP1

6.92e-05111743CID004990817
DrugMDO-CPT

TOP1MT TOP3B TOP1

6.92e-05111743CID000072403
Drugp-acetaminobenzaldehyde thiosemicarbazone

RRM2B TOP1MT DNAH5 TOP3B TOP1

8.82e-05591745CID002733749
DrugSN-38G

ABO ABCG2 TOP1MT TOP3B TOP1

8.82e-05591745CID000443154
DrugAC1L6D6Y

TOP1MT TOP3B TOP1

9.17e-05121743CID000265082
DrugBD-40

TOP1MT TOP3B TOP1

9.17e-05121743CID000068853
DrugAC1L9QTR

TOP1MT TOP3B TOP1

9.17e-05121743CID000453215
Drugellipticine derivative

TOP1MT TOP3B TOP1

9.17e-05121743CID000434612
DrugNC-190

TOP1MT TOP3B TOP1

9.17e-05121743CID000129234
DrugSuccimer

SMG1 CASP8AP2 SLC4A7 RRM2B CYP51A1 RNF213 HMGB2 CREBBP MECP2 FRMD4B NRP2 S100A8 IGF2BP1 SERPINB9 CCDC88A CSGALNACT2 CD80 MNDA ABTB2 MOV10 IGSF3 SYNCRIP GRAP

9.96e-05126417423ctd:D004113
Drugvinblastine

IFNK SLC4A7 SPAST CHRNA1 ABCG2 TOP1MT TOP3B TOP1

1.06e-041891748CID000013342
Drug9-NC

ABCG2 TOP1MT TOP3B TOP1

1.13e-04331744CID000123613
Drugdiflomotecan

ABCG2 TOP1MT TOP3B TOP1

1.13e-04331744CID000219023
Drug4 pN

TOP1MT TOP3B TOP1

1.19e-04131743CID000078607
DrugAC1L8YYB

ABCG2 TOP1MT TOP3B TOP1

1.28e-04341744CID000435167
DrugDorzolamide hydrochloride [130693-82-2]; Up 200; 11uM; MCF7; HT_HG-U133A

SAMD9 JMJD4 NEB MECP2 NEDD9 PGAP1 HERC3 INPP5J

1.32e-0419517486259_UP
DrugAC1L1FWE

PPP3CC PRKDC TOP1MT TOP3B TOP1 AURKB

1.34e-041021746CID000003422
DrugLobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; HL60; HG-U133A

FBXL5 CCDC88A SLC25A40 SP140L SNX6 MCM3AP PDCD11 ARMH3

1.37e-0419617481770_DN
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

FBXL5 PGAP1 MCM3AP VPS13A DNA2 SLC16A7 IL17RB CHP1

1.37e-0419617486058_DN
DrugDicloxacillin

GPT HMGB1 S100A8

1.50e-04141743ctd:D004009
Drug9-hydroxyellipticine

TOP1MT TOP3B TOP1

1.50e-04141743CID000091643
DrugDX-8951f

ABCG2 TOP1MT TOP1

1.50e-04141743CID000151114
DrugAC1L7AJI

CYP2C9 CD80 ABCG2 PRKDC TOP1MT TOP3B TOP1 EP300 AURKB

1.63e-042561749CID000003750
Drugperylenediimide

TOP1MT TOP1

1.73e-0431742CID000066475
Drugchavibetol

TOP1MT TOP1

1.73e-0431742CID000596375
Drug2,2,5,5-tetramethylimidazolidin-4-one

TOP1MT TOP1

1.73e-0431742CID009812798
Drugv 2182

TOP1MT TOP1

1.73e-0431742CID000078632
Drugplakinidine A

TOP1MT TOP1

1.73e-0431742CID005468016
DrugN-ethylethylenediamine

TOP1MT TOP1

1.73e-0431742CID000066071
Drugpotassium hydroxide

PHYHIP APOB NRP2 PRIM1 PLOD2 CRAMP1

1.84e-041081746CID000014797
Drugtanshinone

CYP2C9 HMGB1 ABCG2

1.87e-04151743CID000114917
Drugprotoberberine

TOP1MT TOP3B TOP1

1.87e-04151743CID000114943
Druglurtotecan

ABCG2 TOP1MT TOP1

1.87e-04151743CID000060955
Drugmitoxantrone

IFNK GPT IGDCC4 ABCG2 TOP1MT TOP3B TOP1

1.87e-041541747CID000004212
Diseasemyocardial infarction

HTRA1 ABO VPS72 DOCK9 HECTD4 APOB IGF2BP1 NAA25 ABCG2 CCDC63

3.14e-0535016610EFO_0000612
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.15e-0521662180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.15e-0521662cv:C4551859
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.15e-0521662cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.15e-0521662DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.15e-0521662cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.15e-0521662C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.15e-0521662DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.15e-0521662C0035934
Diseasedrinking behavior

HECTD4 CCDC63

9.40e-0531662EFO_0004315
Diseasealcohol drinking

HECTD4 HEATR1 HMGB1P1 LONRF2 CCDC63

9.63e-05811665EFO_0004329
DiseaseNeurodevelopmental Disorders

SPAST ANK2 MECP2 SMC3 WDFY3

1.85e-04931665C1535926
DiseaseDiffuse Large B-Cell Lymphoma

SGK1 CREBBP ABCG2 EP300

2.63e-04551664C0079744
DiseaseLeukemia, Myelocytic, Acute

SGK1 ANXA4 IDH2 CREBBP S100A8 EP300

4.56e-041731666C0023467
DiseaseFlaccid Muscle Tone

RRM2B MECP2

4.65e-0461662C0026825
DiseaseNeonatal Hypotonia

RRM2B MECP2

4.65e-0461662C2267233
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB CHRNA1

4.65e-0461662C1854678
Diseaseintercellular adhesion molecule 2 measurement

ABO NAA25

4.65e-0461662EFO_0008163
DiseaseMuscle Tone Atonic

RRM2B MECP2

4.65e-0461662C0427202
DiseaseFloppy Muscles

RRM2B MECP2

4.65e-0461662C0427201
Diseaseinterleukin-1 receptor-like 1 measurement

ABO IL18R1

4.65e-0461662EFO_0801713
DiseaseUnilateral Hypotonia

RRM2B MECP2

4.65e-0461662C0751330
Diseasehypertension (is_implicated_in)

HTRA1 CYP2C9 ABO SGK1 MOV10

6.24e-041211665DOID:10763 (is_implicated_in)
Diseaselithostathine-1-alpha measurement

HTRA1 ABO

6.49e-0471662EFO_0801083
Diseaseglypican-1 measurement

NRAP HABP2

6.49e-0471662EFO_0801649
Diseasecoffee consumption

LAMB4 HECTD4 NAA25

7.69e-04321663EFO_0004330
Diseasetea consumption measurement

HECTD4 PHYHIP FRMD4B NAA25 ABCG2

8.33e-041291665EFO_0010091
DiseasePrimary ciliary dyskinesia

ODAD2 DNAH5 RSPH9

1.09e-03361663cv:C0008780
Diseasevisceral heterotaxy (implicated_via_orthology)

ODAD2 PSME4 DNAH5

1.18e-03371663DOID:0050545 (implicated_via_orthology)
DiseaseDrug toxicity

CYP2C9 HMGB1 ABCG2 TOP1

1.31e-03841664C0013221
DiseaseAdverse reaction to drug

CYP2C9 HMGB1 ABCG2 TOP1

1.31e-03841664C0041755
Diseaseobstructive jaundice (biomarker_via_orthology)

GPT HMGB1

1.37e-03101662DOID:13603 (biomarker_via_orthology)
Diseaselipoprotein-associated phospholipase A(2) measurement

RNF213 APOB ABCG2

1.48e-03401663EFO_0004746
Diseasehigh grade glioma (implicated_via_orthology)

HMGB1 IDH2 CD80

1.96e-03441663DOID:3070 (implicated_via_orthology)
Diseasealcohol consumption measurement, alcohol drinking

HECTD4 CCDC63

2.00e-03121662EFO_0004329, EFO_0007878
DiseasePrimary Ciliary Dyskinesia

ODAD2 DNAH5 RSPH9

2.36e-03471663C4551720
DiseaseKartagener syndrome (implicated_via_orthology)

ODAD2 DNAH5

2.74e-03141662DOID:0050144 (implicated_via_orthology)
Diseaselipoprotein measurement

ABO APOB NAA25 TASOR

2.97e-031051664EFO_0004732
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

ABO APOB

3.15e-03151662EFO_0022328
Diseaseresponse to statin, LDL cholesterol change measurement

APOB ABCG2

3.15e-03151662EFO_0007804, GO_0036273
DiseaseMuscle hypotonia

RRM2B MECP2

4.05e-03171662C0026827
DiseaseMoyamoya Disease

HTRA1 RNF213

4.05e-03171662C0026654
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

ABO APOB

4.05e-03171662EFO_0022232
DiseaseX-12063 measurement

DNAH14 HMGB1P1 MACO1 DNAH5 PGBD5

4.12e-031861665EFO_0021283
Diseasecreatine kinase measurement

ABO NEB IQGAP3

4.51e-03591663EFO_0004534
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

ABO APOB MACO1 TOP1

4.79e-031201664EFO_0004611, EFO_0004639
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

ABO SPG11 APOB

4.96e-03611663EFO_0008317, EFO_0008596, EFO_0020946
Diseasediabetes mellitus (biomarker_via_orthology)

CYP51A1 ABCG2

5.05e-03191662DOID:9351 (biomarker_via_orthology)
Diseasecerebral infarction (is_marker_for)

HMGB1 APOB

5.05e-03191662DOID:3526 (is_marker_for)
Diseasefactor VIII measurement, Ischemic stroke

ABO HECTD4

5.05e-03191662EFO_0004630, HP_0002140
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

ABO APOB NAA25

5.42e-03631663EFO_0001645, EFO_0004792
DiseaseAcute Myeloid Leukemia, M1

SGK1 ANXA4 IDH2 S100A8

5.52e-031251664C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

SGK1 ANXA4 IDH2 S100A8

5.52e-031251664C1879321

Protein segments in the cluster

PeptideGeneStartEntry
LEKLSRFHAKFTLEY

GPT

481

P24298
DFLEKIAKLYELHVF

CTDP1

231

Q9Y5B0
SERIVHDYKDIFKQA

EP300

1476

Q09472
SFLKAYVHEFKFRSI

RNPEP

436

Q9H4A4
YVAFLKLFLETAEKH

ABO

126

P16442
AAEFYVTHEILKKVA

CXorf58

71

Q96LI9
AVDKVELFLKEYLHF

NEDD9

451

Q14511
ELFLKEYLHFVKGAV

NEDD9

456

Q14511
AVVTYIAFHKLRKDY

ADGRG4

2761

Q8IZF6
YTKTVIEFRHKRKVF

GSG1L

241

Q6UXU4
QHFKVLREASGKYFL

GRAP

106

Q13588
ELFVVEKKLFIHEYI

ABCG2

446

Q9UNQ0
FAERIIHDYKDIFKQ

CREBBP

1511

Q92793
YSEQHKEAAFFKELV

ARMH3

646

Q5T2E6
LRYIAEKTEFFKHVA

DOP1A

861

Q5JWR5
LHVFDEYKRISQKDI

ANXA4

206

P09525
YEKDAFKREHLAEVT

CD80

121

P33681
FKAKFSLIQFHRIIE

CASP8AP2

1056

Q9UKL3
RLYEVKLVAFNKHED

IGDCC4

711

Q8TDY8
DHKVEEFIKSIFYSV

RAD54B

391

Q9Y620
RVKKIRDYAFVHFTS

RBM47

276

A0AV96
FKKHRAARIDHYVVE

RBSN

106

Q9H1K0
DRVSKEFIEFLKTFH

RABGEF1

136

Q9UJ41
KSADFHKREIEYFRK

RGS11

221

O94810
DHEVLTFIKYKVFDA

HNRNPLL

476

Q8WVV9
DAIRAIYAEDHKLVF

MON1B

151

Q7L1V2
SEHETRLVAKLFKDY

CHRNA1

21

P02708
KESKEHFFDLYRNSI

ANK2

3461

Q01484
IHRAVFYRDLEELKF

ANKRD36C

36

Q5JPF3
NTLFHAYKREEAIKE

RSPH10B

771

P0C881
NTLFHAYKREEAIKE

RSPH10B2

771

B2RC85
RKFGSKYLVDHEVHF

FBLN7

91

Q53RD9
ALVYRDRETLKFVKH

OGFOD1

501

Q8N543
KHFGYKLCIFERDVV

IL18R1

406

Q13478
RSVNTHDYAKVKEFI

MATN2

66

O00339
REINFEYLKHVVLKF

GOLGA1

691

Q92805
YAFFVQTCREEHKKK

HMGB1

16

P09429
DEKDNTKRFLFHYSK

NMU

96

P48645
KFFTRHIDLYDKDEI

MCM8

101

Q9UJA3
EFVNFFLLHYKKEVS

MCOLN3

316

Q8TDD5
FLYRHDFVKERGKLI

NRAP

1306

Q86VF7
YAFFVQTCREEHKKK

HMGB2

16

P26583
SFLVHESFLYKREKA

FLYWCH1

281

Q4VC44
KSFIEAVEKYFDHLI

GLB1L3

191

Q8NCI6
FKRLDKFAAEHTIFA

HADH

131

Q16836
ADRFKYHIVKQIFSG

HERC3

356

Q15034
ADLEKVFAEHKISYS

IGF2BP1

16

Q9NZI8
FTRRSKKLAVVHFFD

MCM3AP

466

O60318
HKYVVVYFREIDTKD

IL17RB

441

Q9NRM6
TAHFHLKRKIGYFVI

GABRA2

241

P47869
LVEFSHKELFDFYNK

COMMD10

176

Q9Y6G5
LHDIEFYKARVEELK

CCDC88A

336

Q3V6T2
RVKKLKDYAFIHFDE

SYNCRIP

366

O60506
FVYIEAAIRFKDLKN

MACO1

131

Q8N5G2
LYEFHNRTFLKELEK

MCF2L2

676

Q86YR7
SHFTKRDEEILLKYL

PDE6A

201

P16499
DLLYIRDHFDKKQVF

FAM151B

241

Q6UXP7
RDHFDKKQVFYDILE

FAM151B

246

Q6UXP7
EARAFVRKFKVSYSL

NRP2

516

O60462
EKVNKYLDFSLFKHR

SLC16A7

231

O60669
KEFAEKLESLLHRAY

MIGA2

231

Q7L4E1
VLYFILGLHFEEDKK

LONRF2

371

Q1L5Z9
KYLTLEGFHKFVIDR

HECTD4

3406

Q9Y4D8
NDYLEETHLKFRKFI

IQGAP3

1236

Q86VI3
KIETHLFAFEIYFRK

NAA15

671

Q9BXJ9
EVYHEKDIKVFFDKA

PLOD2

336

O00469
YVKVFEHFLENLDKS

PRIM1

391

P49642
ARFEKILKYFHVVAF

PGBD5

206

Q8N414
KKGVFQRVVAIFIHY

FBXO38

1161

Q6PIJ6
FHYIREALKSDKLAQ

QTRT2

391

Q9H974
ENLYFREKKFSVEVH

FRMD4A

261

Q9P2Q2
DLVASHFNLKEKEYF

FRMD4B

86

Q9Y2L6
HFNLKEKEYFGITFI

FRMD4B

91

Q9Y2L6
NLYFREKKFAVEVHD

FRMD4B

301

Q9Y2L6
HEQSFRVEKIFKYSH

HABP2

386

Q14520
VIRKGSKNDFFLHYI

APOB

816

P04114
FFKKADLTEYRHVTL

CSGALNACT2

236

Q8N6G5
TELEKEFHFNKYLSR

HOXB1

216

P14653
RFKDIFQEIFDKHYK

IDH2

261

P48735
VAKESDSVFVLKIYH

IGSF3

351

O75054
RHKYNFIADVVEKIA

HTRA1

166

Q92743
ELERLYAHESKLKSF

CCDC63

251

Q8NA47
IKYNRKISADFHVDL

DOCK9

406

Q9BZ29
YISALRKLFDQHKVE

DGAT2L6

311

Q6ZPD8
RFIHGKDVFEAFYKK

CUL4A

441

Q13619
EEFYHFLKVIAEKRL

JMJD4

381

Q9H9V9
RAHREIKDIFYKAIQ

CYP51A1

261

Q16850
HKITKYIDFDHVFSR

CRAMP1

221

Q96RY5
FHRIDNFLKEKKYSD

IFNK

166

Q9P0W0
ISRFEDTLKHYKVYK

CFAP100

246

Q494V2
ELELKARVFHFGEYK

CFAP100

456

Q494V2
FLVKVGFLKILHRYE

C20orf27

51

Q9GZN8
LAKVTYDFDKLVHEL

DNAH14

1801

Q0VDD8
QKFDTLLAAFRHYDK

EFHB

561

Q8N7U6
YAFFVQTCREEHKKK

HMGB3

16

O15347
FLKVKDYHDSVRRQI

LAMB4

1241

A4D0S4
KIFLFDTQHFISKER

HEATR1

2001

Q9H583
HAEERQKFFKYSVDE

FBXL5

176

Q9UKA1
NVICSIIFHKRFDYK

CYP2C9

176

P11712
SDRDKFVIFLDVKHF

CRYAA

66

P02489
AKLYEFVHSFQDEKR

DNAJC22

261

Q8N4W6
RHFKDVKLELEFYAD

DNA2

861

P51530
KKLAFAYLEDLHSEF

SEC22B

81

O75396
KVASAYFKDFHLLLI

SLC13A1

76

Q9BZW2
EVFFHRYYKKVAVKE

CEBPZ

811

Q03701
SVKFHEKIYDRILSI

DNAH5

1751

Q8TE73
KFIYGEKHVEVRTLA

DNAH5

3186

Q8TE73
FLGLKRVVTDKHFYF

HS3ST6

266

Q96QI5
TRKHFLDYFDAVIPK

MTBP

506

Q96DY7
AKYLREFHSVERKFA

NAP1L6P

66

A6NFF2
RYAREHLAKSKLEVF

PLA2G4D

386

Q86XP0
AFRSKVELIAYFEKV

MECP2

131

P51608
YFHVKVFDINLKEKF

MNDA

246

P41218
LKELEQKDFRLFHSY

METTL24

321

Q5JXM2
ALEIFQHSKYKVDFI

MRPL39

226

Q9NYK5
AKKLSSYFHFREPVE

RSPH9

181

Q9H1X1
FHAVYRDDLKKLLET

S100A8

26

P05109
KFEKEELESHRAVYI

SLC4A7

31

Q9Y6M7
FYGVKFRNKVSHIDV

SMC3

1186

Q9UQE7
YVELHRFVSKKVSED

SLC25A40

176

Q8TBP6
ITYKGFVHKVELDRV

MOV10

411

Q9HCE1
AKFKELIFQVRHTYE

RIT2

111

Q99578
VVKAYKESRVANLHF

SAMD9

451

Q5K651
LKEIIVFVESFIYKH

ODAD2

31

Q5T2S8
HIIKLTFEDFAVKFS

OVCH1

456

Q7RTY7
KVLLARHKAEEVFYA

SGK1

111

O00141
RHKAEEVFYAVKVLQ

SGK1

116

O00141
LFLRYHKEKEVVAVA

SMG1

531

Q96Q15
YAFFVQTCREEHKKK

HMGB1P1

16

B2RPK0
AHVVLKEEQKFRYLF

MEP1A

391

Q16819
TQFLQYFLEKREKHV

THNSL2

121

Q86YJ6
SIALRKAEDIDFKYH

PGAP1

106

Q75T13
LERVTHYFIDLNKKE

PHYHIP

31

Q92561
RTYHLCEVLFKVHKF

SNTG2

346

Q9NY99
VRVFHKQAFEYISIA

SPAST

116

Q9UBP0
EGLVYDTVFKHFKRH

SP140L

46

Q9H930
EFEKLSDFFKTHYRL

SSRP1

81

Q08945
HSVVEKYVSEFFKRG

TASOR

551

Q9UK61
DVTFLVEGKLFYAHK

ABTB2

846

Q8N961
KHSKDIARFTFDVYK

CIDEB

126

Q9UHD4
HFAFRLYDLDKDEKI

CHP1

116

Q99653
TRAEFQAKIDAVKHY

CNGA2

381

Q16280
VYLAREKKSHFIVAL

AURKB

91

Q96GD4
VRDFFPTVFVKEKHY

PROKR1

306

Q8TCW9
LKADEKYFISHILAF

RRM2B

81

Q7LG56
FRIESYDLHFVKFAI

INPP5J

606

Q15735
YFSEKEKRTIDFVHQ

SPG11

781

Q96JI7
HLTDYFTFKQECRIK

PPP3CC

151

P48454
FRLIVIEEKDVVYKH

RNF213

3146

Q63HN8
VLGHTLDVFKRKFHY

TOP3B

581

O95985
LDVFKRKFHYFVDSI

TOP3B

586

O95985
LKVFLHLADIYAKSE

PDCD11

1691

Q14690
TEHKRFLAFEVKEYS

RWDD3

226

Q9Y3V2
FKDDLFRKYVQFHES

SPATA2

11

Q9UM82
YFEKILHFIKDRILV

TTC13

616

Q8NBP0
KVFQLIFYFKEHERI

ZNF540

306

Q8NDQ6
ELHRFVSVSKLKYFF

YIF1A

81

O95070
KFFLDSYKLVIHQRI

ZNF749

591

O43361
FHKDIEAFKEEYKTA

VPS13A

2741

Q96RL7
IKLSFKEHGQIEFYR

VPS36

106

Q86VN1
LLKFTRHDYIFKDVF

WDFY3

486

Q8IZQ1
FYHAELKELSFIRAA

SERPINB9

111

P50453
VDHVFREVKDAAKLY

RINT1

611

Q6NUQ1
SAVYDVFVFHRLKIK

TMTC2

196

Q8N394
FEKYLVKLSDFDREH

XRN1

336

Q8IZH2
DHEYTTKEVFRKNFF

TOP1MT

101

Q969P6
DIALFHLKKAVRYND

TMPRSS12

171

Q86WS5
DKRVKDFLHAVYATL

SERPINE3

86

A8MV23
VFEKKYHQVDVRFPA

PPP1R36

331

Q96LQ0
RIIFVFDFKKVSLLH

nan

206

Q6ZUG5
YGRKFSKEDHVLFIK

PSME4

86

Q14997
FLLEYHNRVKDASAK

SNX6

216

Q9UNH7
TECRHKSIELFYKFV

PRKDC

1181

P78527
IEALKNRFKYFESDH

UACA

366

Q9BZF9
HLFLKYSFRKDIFGD

PRSS21

206

Q9Y6M0
FQKIFKEEYRIHITG

TMEM117

286

Q9H0C3
FKIIREAYKKYITAH

VPS72

316

Q15906
YKHETEFAELEVKTR

YEATS4

166

O95619
HEYTTKEIFRKNFFK

TOP1

266

P11387
FRHDKVYVIGSFVDK

TRMT10C

301

Q7L0Y3
KYRVDFHNFSKTVEV

KCNJ1

336

P48048
LAKKIYAHLFDFIVE

MYO5C

401

Q9NQX4
HYSAEKAVKFIEDRI

NAA25

296

Q14CX7
VKVAAHKLYESLGFR

NAT8L

251

Q8N9F0
SHIKYREEYEKFKAL

NEB

4736

P20929
KYHTVKDALDIVYHR

NEB

5276

P20929