Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction6-phosphofructokinase activity

PFKL PFKM

1.02e-0431172GO:0003872
GeneOntologyBiologicalProcessglycolytic process through glucose-6-phosphate

GALE FOXK2 PFKL PFKM

1.13e-05251174GO:0061620
GeneOntologyBiologicalProcessepithelium development

FLG FLNB ABL1 CEBPA KRT19 COL27A1 PDZD7 RIPK4 SIPA1 TEK KRT23 ESRP2 FOXP4 FASN SALL2 MEGF8 ZFP36L1 TMEM132E PKP3 PKHD1 NUMB FOXP3

2.37e-05146911722GO:0060429
GeneOntologyBiologicalProcessglycolytic process through fructose-6-phosphate

GALE FOXK2 PFKL PFKM

2.75e-05311174GO:0061615
GeneOntologyBiologicalProcessepithelial cell differentiation

FLG FLNB ABL1 CEBPA KRT19 COL27A1 PDZD7 SIPA1 KRT23 FOXP4 FASN ZFP36L1 TMEM132E PKHD1 NUMB FOXP3

3.26e-0587011716GO:0030855
GeneOntologyCellularComponent6-phosphofructokinase complex

PFKL PFKM

9.28e-0531172GO:0005945
Domain6-Pfructokinase_euk

PFKL PFKM

1.14e-0431162IPR009161
DomainPHOSPHOFRUCTOKINASE

PFKL PFKM

1.14e-0431162PS00433
DomainPhosphofructokinase_CS

PFKL PFKM

1.14e-0431162IPR015912
DomainPFK

PFKL PFKM

1.14e-0431162PF00365
DomainATP_PFK

PFKL PFKM

1.14e-0431162IPR022953
DomainPhosphofructokinase_dom

PFKL PFKM

1.14e-0431162IPR000023
DomainFOXP-CC

FOXP4 FOXP3

2.28e-0441162PF16159
DomainFOXP-CC

FOXP4 FOXP3

2.28e-0441162IPR032354
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXK2 ABL1 ZNF48 LPAR5 KIF26A BICRA EMID1 GRIN2D MDFI FAAP100 ADGRA2 CIC ZNF503 ESRP2 JUNB FASN CELSR3 MEGF8 ARAP1 BAHCC1

1.16e-0911051192035748872
Pubmed

Regulatory T-cells and micrometastasis in lymph nodes of stage I NSCLC.

KRT19 FOXP3

1.16e-052119225503147
Pubmed

Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.

PFKL PFKM

1.16e-052119229655163
Pubmed

Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.

ABL1 ERN1

1.16e-052119228380378
Pubmed

Isozyme analysis of human polymorphonuclear leukocyte phosphofructokinase from insulin resistant individuals.

PFKL PFKM

1.16e-05211928780720
Pubmed

Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.

ABL1 GRIN2D

1.16e-052119210777567
Pubmed

The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.

PFKL PFKM

1.16e-05211926444532
Pubmed

Clinicopathological characterization and prognostic implication of FOXP3 and CK19 expression in papillary thyroid carcinoma and concomitant Hashimoto's thyroiditis.

KRT19 FOXP3

1.16e-052119232606302
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

1.16e-052119229317596
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

1.16e-052119233766086
Pubmed

Regulatory T cells sense effector T-cell activation through synchronized JunB expression.

JUNB FOXP3

1.16e-052119231017652
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

1.16e-052119229651654
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

1.16e-052119231110197
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

1.16e-052119235057644
Pubmed

SIRT3 promotes the invasion and metastasis of cervical cancer cells by regulating fatty acid synthase.

SIRT3 FASN

1.16e-052119231677030
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

1.16e-052119231786200
Pubmed

The glycolytic enzyme phosphofructokinase-1 assembles into filaments.

PFKL PFKM

1.16e-052119228646105
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

BICRA APC2 DDN CIC PLCH2 NUMB IRF2BPL MAML2 ARAP1

1.81e-05430119935044719
Pubmed

Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.

GRIN2C GRIN2D KCNB1

2.56e-0517119324086760
Pubmed

Gene structure and chromosomal localization of the mouse NMDA receptor channel subunits.

ABL1 GRIN2C GRIN2D

3.07e-051811939011744
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

3.47e-05311929718984
Pubmed

Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.

PFKL PFKM

3.47e-05311927825568
Pubmed

Bcr/Abl P190 interaction with Spa-1, a GTPase activating protein for the small GTPase Rap1.

ABL1 SIPA1

3.47e-053119218813851
Pubmed

Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.

PFKL PFKM

3.47e-05311926444721
Pubmed

Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.

PFKL PFKM

3.47e-053119211137296
Pubmed

JunB regulates homeostasis and suppressive functions of effector regulatory T cells.

JUNB FOXP3

3.47e-053119230559442
Pubmed

Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers.

SIRT3 FOXP3

3.47e-053119225109285
Pubmed

c-Abl-mediated tyrosine phosphorylation of JunB is required for Adriamycin-induced expression of p21.

ABL1 JUNB

3.47e-053119226217035
Pubmed

Reciprocal effects of C/EBPalpha and PKCdelta on JunB expression and monocytic differentiation depend upon the C/EBPalpha basic region.

CEBPA JUNB

3.47e-053119212522006
Pubmed

JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation.

JUNB FOXP3

3.47e-053119221371435
Pubmed

Phosphofructokinase isozyme expression during myoblast differentiation.

PFKL PFKM

3.47e-05311922521854
Pubmed

Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.

PFKL PFKM

3.47e-053119233141153
Pubmed

Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.

GRIN2C GRIN2D

3.47e-053119235867797
Pubmed

Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.

PFKL PFKM

3.47e-0531192156693
Pubmed

Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.

PFKL PFKM

3.47e-05311926451249
Pubmed

Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model.

GRIN2C GRIN2D

3.47e-053119233421565
Pubmed

Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels.

GRIN2C GRIN2D

3.47e-05311929480759
Pubmed

Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.

PFKL PFKM

3.47e-05311922960695
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

PFKL FOXP4 FASN CLK3 ACIN1 IRF2BPL RBM34 FOXP3

4.28e-05370119822922362
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CASC3 FLNB FOXK2 BICRA PFKL TARS2 MAP3K12 DENND2B CASK FOXP4 PTPN13 PKP3 NUMB C1orf159 TMEM143 ARAP1

4.95e-0514891191628611215
Pubmed

Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua.

CIC FOXP3

6.93e-054119234895467
Pubmed

The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway.

ABL1 GRAP2

6.93e-054119220079431
Pubmed

IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis.

ERN1 KRT19

6.93e-054119235170357
Pubmed

Identification and characterization of T reg-like cells in zebrafish.

FOXP4 FOXP3

6.93e-054119229066577
Pubmed

Activation of extracellular signal-regulated kinase 2 by a novel Abl-binding protein, ST5.

ABL1 DENND2B

6.93e-05411929632734
Pubmed

Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs.

GRIN2C GRIN2D

6.93e-054119236309015
Pubmed

PD-1+ memory phenotype CD4+ T cells expressing C/EBPalpha underlie T cell immunodepression in senescence and leukemia.

CEBPA SIPA1

6.93e-054119219805226
Pubmed

Functional correlation of NMDA receptor epsilon subunits expression with the properties of single-channel and synaptic currents in the developing cerebellum.

GRIN2C GRIN2D

6.93e-05411928699248
Pubmed

Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel.

GRIN2C GRIN2D

6.93e-05411929768843
Pubmed

Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.

FOXK2 RIPK4 JUNB PTPN13 RNF5 CLK3 RBM34

7.49e-05296119734186245
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

FLNB SPTLC2 PFKL TARS2 EXOC8 SORCS1 KRT23 PCF11 FASN RNF5

8.01e-056471191026618866
Pubmed

Synapse-selective impairment of NMDA receptor functions in mice lacking NMDA receptor epsilon 1 or epsilon 2 subunit.

GRIN2C GRIN2D

1.15e-04511929147327
Pubmed

Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain.

GRIN2C GRIN2D

1.15e-045119221945132
Pubmed

Roles of the glutamate receptor epsilon2 and delta2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex.

GRIN2C GRIN2D

1.15e-045119211488959
Pubmed

Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina.

GRIN2C GRIN2D

1.15e-04511927510577
Pubmed

Altered expressions and splicing profiles of Acin1 transcripts differentially modulate brown adipogenesis through an alternative splicing mechanism.

ERN1 ACIN1

1.15e-045119232629174
Pubmed

Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord.

GRIN2C GRIN2D

1.15e-04511927929904
Pubmed

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design.

GRIN2C GRIN2D

1.15e-045119226919761
Pubmed

Distinct distributions of five NMDA receptor channel subunit mRNAs in the brainstem.

GRIN2C GRIN2D

1.15e-04511927518475
Pubmed

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum.

GRIN2C GRIN2D

1.15e-04511927518474
Pubmed

Neurotransmission and bipolar disorder: a systematic family-based association study.

GRIN2C GRIN2D

1.15e-045119218444252
Pubmed

Distinct gene expression of the N-methyl-D-aspartate receptor channel subunit in peripheral neurons of the mouse sensory ganglia and adrenal gland.

GRIN2C GRIN2D

1.15e-04511928015722
Pubmed

Inducible and reversible NR1 knockout reveals crucial role of the NMDA receptor in preserving remote memories in the brain.

GRIN2C GRIN2D

1.15e-045119215003177
Pubmed

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions.

GRIN2C GRIN2D

1.15e-04511927723623
Pubmed

Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor.

GRIN2C GRIN2D

1.15e-045119212082569
Pubmed

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

GRIN2C GRIN2D

1.15e-04511921493227
Pubmed

N-methyl-D-aspartic acid receptor structure and function.

GRIN2C GRIN2D

1.15e-04511928036251
Pubmed

NMDA receptor activation by HIV-Tat protein is clade dependent.

GRIN2C GRIN2D

1.15e-045119219020013
Pubmed

Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.

SIRT3 FOXP3

1.15e-045119225681462
Pubmed

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.

GRIN2C GRIN2D

1.15e-045119226875626
Pubmed

Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene.

GRIN2C GRIN2D

1.15e-04511928756432
Pubmed

Differential interaction of NMDA receptor subtypes with the post-synaptic density-95 family of membrane associated guanylate kinase proteins.

GRIN2C GRIN2D

1.15e-045119218233995
Pubmed

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.

CIC FOXP3

1.15e-045119228855737
Pubmed

During embryogenesis, esrp1 expression is restricted to a subset of epithelial cells and is associated with splicing of a number of developmentally important genes.

CASK ESRP2

1.15e-045119223233200
Pubmed

Maternal synchronization of gestational length and lung maturation.

CEBPA TEK FASN

1.64e-0431119322096492
Pubmed

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.

GRIN2C GRIN2D

1.73e-046119223665428
Pubmed

Altered gene expression of the N-methyl-D-aspartate receptor channel subunits in Purkinje cells of the staggerer mutant mouse.

GRIN2C GRIN2D

1.73e-04611928996814
Pubmed

Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine.

GRIN2C GRIN2D

1.73e-046119225760043
Pubmed

Regulation by afadin of cyclical activation and inactivation of Rap1, Rac1, and RhoA small G proteins at leading edges of moving NIH3T3 cells.

SIPA1 ARAP1

1.73e-046119219589776
Pubmed

Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo.

GRIN2C GRIN2D

1.73e-04611929458051
Pubmed

NMDA receptor GluRepsilon/NR2 subunits are essential for postsynaptic localization and protein stability of GluRzeta1/NR1 subunit.

GRIN2C GRIN2D

1.73e-046119215317856
Pubmed

Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment.

JUNB FOXP3

1.73e-046119233361391
Pubmed

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core.

CASC3 ACIN1

1.73e-046119216314458
Pubmed

Genetic mapping in the mouse of four loci related to the jun family of transcriptional activators.

ABL1 JUNB

2.41e-04711921887331
Pubmed

Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus.

GRIN2C GRIN2D

2.41e-047119212103442
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2C GRIN2D

2.41e-047119223267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2C GRIN2D

2.41e-047119219036954
Pubmed

Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes.

PTPN13 HOXC8

2.41e-047119227025388
Pubmed

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

GRIN2C GRIN2D

2.41e-047119222940423
Pubmed

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.

GRIN2C GRIN2D

2.41e-047119222833210
Pubmed

CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development.

CEBPA ERN1 KRT19

2.57e-0436119330635284
Pubmed

HIV-1 subtypes B and C Tat differentially impact synaptic plasticity expression and implicates HIV-associated neurocognitive disorders.

GRIN2C GRIN2D JUNB

3.02e-0438119325613138
Pubmed

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.

GRIN2C GRIN2D

3.21e-04811928563977
Pubmed

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.

GRIN2C GRIN2D

3.21e-04811927695237
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2C GRIN2D

3.21e-048119217360663
Pubmed

Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.

GRIN2C GRIN2D

3.21e-04811928724036
Pubmed

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.

GRIN2C GRIN2D

3.21e-04811928822372
Pubmed

Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production.

GRIN2C GRIN2D

3.21e-048119221106831
Pubmed

Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.

GRIN2C GRIN2D

3.21e-048119210448428
Pubmed

Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.

GRIN2C GRIN2D

3.21e-04811928955056
InteractionTOP3B interactions

FOXK2 ABL1 ZNF48 LPAR5 KIF26A BICRA EMID1 GRIN2D PFKL MDFI FAAP100 ADGRA2 CIC ZNF503 ESRP2 JUNB FASN ERLIN2 CELSR3 MEGF8 RMDN1 ACIN1 ARAP1 BAHCC1

3.20e-06147011724int:TOP3B
Cytoband17q25

FOXK2 GRIN2C FASN

1.45e-0439119317q25
Cytoband11q13

SIPA1 KCNK4 NDUFS8 PCF11

2.62e-04118119411q13
CytobandEnsembl 112 genes in cytogenetic band chr15q24

ISLR LMAN1L CLK3 STOML1

2.98e-041221194chr15q24
CytobandEnsembl 112 genes in cytogenetic band chr17q25

FOXK2 GRIN2C FAAP100 FASN BAHCC1

1.27e-033071195chr17q25
Cytoband14q24.3

SPTLC2 NUMB IRF2BPL

1.86e-0393119314q24.3
CytobandEnsembl 112 genes in cytogenetic band chr14q24

SPTLC2 ZFP36L1 NUMB IRF2BPL

1.88e-032001194chr14q24
Cytoband19q13.33

ODAD1 GRIN2D TMEM143

2.70e-03106119319q13.33
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

4.31e-0478321201
GeneFamilyAnkyrin repeat domain containing

ANKRD13B ANKRD65 RIPK4 ANKZF1 ANKRD53 ARAP1

8.64e-04242836403
GeneFamilyForkhead boxes

FOXK2 FOXP4 FOXP3

1.01e-0343833508
CoexpressionPEREZ_TP53_TARGETS

FNIP2 FLG ANKRD65 CEBPA LPAR5 KIF26A COL27A1 APC2 KCP RIPK4 KRT23 ESRP2 JUNB FOXP4 KCNB1 CLK3 IRF2BPL ARAP1

7.10e-06120111818M4391
CoexpressionBENPORATH_SUZ12_TARGETS

DCHS2 LINC02875 COL27A1 CDC20B HLX RIPK4 GRIN2D ADGRA2 KCNK4 ZNF503 SORCS1 KL HOXC8 NEUROD2 TMEM132E PODN

1.66e-05103511816M9898
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

KRT19 GLB1L3 CYP4B1 RIPK4 PTPN13 SRGAP3 PLCH2

7.24e-0718711978407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellkidney_cells-Hypertensive_with+without-CKD|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

KRT19 SPTLC2 ZNF503 PTPN13 SRGAP3 PKHD1 IRF2BPL

7.51e-07188119790188b60ff893754f7938fe8edab79758827168e
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ANKRD65 CEBPA COL27A1 ESRP2 FASN PTPN13 CDCA7

7.78e-0718911972d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT19 EMID1 RIPK4 PFKL MDFI KRT23 PKP3

8.64e-07192119718546b4d5e39aafa97186104d47cfda02eb5f4b5
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLG DCHS2 CDC20B VWA7 PKHD1 PODN SH2D7

8.95e-071931197315840bc48899f3a36d57b19197509de19716e3d
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 GLB1L3 RIPK4 MDFI NEUROD2 SRGAP3 PLCH2

1.03e-0619711971e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 FASN PTPN13 PKP3

1.06e-061981197655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

KRT19 CYP4B1 RIPK4 FOXP4 PKP3 PKHD1 CACNA2D3

1.14e-0620011972dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FNIP2 ANKRD65 CEBPA ZNF503 FBLN2 SRGAP3 CACNA2D3

1.14e-0620011974a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCelldistal-Epithelial-Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLG KRT19 GLB1L3 CYP4B1 MDFI PKP3 PNLIPRP3

1.14e-0620011975c14f0c09bb8b3daf6d649032e888a7880c52b73
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 GLB1L3 CYP4B1 RIPK4 MDFI PKP3 PLCH2

1.14e-0620011970594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs|GI_large-bowel / Manually curated celltypes from each tissue

DENND2B KL PTPN13 PKHD1 DNAH6 FOXP3

4.93e-0616211969a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

FLNB MDFI ZNF503 SORCS1 SLC4A10 BAHCC1

5.67e-061661196773673a5d0430640439845b264740bfbbdad0cb2
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

EMID1 MDFI ZNF503 SORCS1 KL SLC4A10

6.49e-06170119697df5ffb328196c46568975d2d97722bcc753bf5
ToppCelldroplet-Marrow-nan-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXK2 POT1 MDFI TARS2 MEGF8 BAHCC1

7.42e-06174119655cc8300489d11322724159ec7d0e1d32a702e91
ToppCellfacs-Marrow-T_cells-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 PTPN13 ZFP36L1 GRAP2 IRF2BPL FOXP3

7.66e-061751196d3d574962c0a4a0d64db120320f0d04e11d2c9d8
ToppCellfacs-Marrow-T_cells|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 PTPN13 ZFP36L1 GRAP2 IRF2BPL FOXP3

7.66e-0617511964d77fade9ab87b79ac206d074b0e2ef8930c044e
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KRT19 CYP4B1 RIPK4 PKP3 PKHD1 CACNA2D3

8.45e-0617811961817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CYP4B1 ITGA10 MDFI TEK TMEM132E

8.72e-061791196025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KRT19 CYP4B1 RIPK4 PKP3 PKHD1 CACNA2D3

9.59e-061821196cc79e0cc21e2fdc4ef77f052818d27b9f707aec1
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KRT19 CYP4B1 RIPK4 PKP3 PKHD1 CACNA2D3

9.89e-061831196274483009b309289e4cb84beedf6806430db6ff6
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ANKRD65 KRT19 GLB1L3 CYP4B1 RIPK4 PLCH2

1.02e-0518411961f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

ERN1 EMID1 SORCS1 ZFP36L1 SRGAP3 SLC4A10

1.02e-051841196d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

EMID1 ZNF503 SORCS1 ZFP36L1 SRGAP3 SLC4A10

1.02e-051841196479e60f76c191253e23699c9dd7ef7efc08c59ad
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABL1 C1RL FBLN2 ZFP36L1 PODN CACNA2D3

1.05e-0518511969faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellfacs-Skin-nan-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 C1RL ISLR FBLN2 SRGAP3 PODN

1.05e-0518511968433a337625ff8398520e223ef92bf9bb0beb14c
ToppCellfacs-Skin-nan-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 C1RL ISLR FBLN2 SRGAP3 PODN

1.05e-051851196049d793d043d5d434f143025de49dd210d18756c
ToppCellfacs-Skin-nan-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT4 C1RL ISLR FBLN2 SRGAP3 PODN

1.05e-05185119663200c42565eea596f9b00728e70e544b8d50a7f
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA MDFI JUNB FOXP4 ZFP36L1 PLCH2

1.08e-051861196bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP4B1 RIPK4 FOXP4 PTPN13 PKHD1 CACNA2D3

1.08e-0518611964e94158db52df41d71e67b02b9895a358eebee0f
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT19 CYP4B1 RIPK4 KRT23 PKP3 PLCH2

1.12e-051871196380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT19 CYP4B1 RIPK4 KRT23 PKP3 PLCH2

1.12e-0518711965b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT19 CYP4B1 RIPK4 KRT23 PKP3 PLCH2

1.12e-051871196796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT19 CYP4B1 RIPK4 KRT23 ESRP2 PLCH2

1.12e-051871196fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT19 CYP4B1 RIPK4 KRT23 ESRP2 PLCH2

1.15e-0518811968ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL27A1 EMID1 ITGA10 DENND2B PTPN13 MAML2

1.15e-051881196997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT19 CYP4B1 RIPK4 KRT23 ESRP2 PLCH2

1.15e-051881196137ed9958044fab7a13648affb469585d1c48cf6
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEBPA MDFI JUNB FOXP4 ZFP36L1 PLCH2

1.19e-051891196965e0e388251e7318f8b463816dc96ccb4658677
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDFI VWA7 PCF11 JUNB ZFP36L1 NUMB

1.22e-05190119692456f6f7eced6e4c4371f495254a65d061c8d0b
ToppCellfacs-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEBPA KRT19 RIPK4 KRT23 ESRP2 PLCH2

1.34e-0519311968e934f127bc763e905c788beabfa867bd559b682
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CYP4B1 TEK ADGRA2 ZNF503 KCNB1

1.34e-051931196d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell18-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

KRT19 RIPK4 JUNB ZFP36L1 PKP3 PLCH2

1.34e-0519311965067b0db24f96e26cf3f9437736415f694e7a614
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCP AGBL4 PTPN13 SRGAP3 PKHD1 CACNA2D3

1.38e-05194119693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellAT2|World / shred by cell class for parenchyma

GALE CEBPA KRT19 FASN PTPN13 TMEM41B

1.38e-051941196e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLG ANKRD65 KRT19 RIPK4 MDFI KRT23

1.42e-051951196dd8117dbd22892288f74a7314ab0b5080106936c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLG ANKRD65 KRT19 RIPK4 MDFI KRT23

1.42e-05195119682d87fdb39ec15be9057e2d2ba5c1afb5f97aafe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DNAAF9 AGBL4 PTPN13 SRGAP3 PKHD1 CACNA2D3

1.42e-0519511966477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellmild-dn_T|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

FLNB LPAR5 CYP4B1 CASK CDCA7 RAB27A

1.42e-051951196158f0f229bad71cc9b06b7399168982bbbbd1d47
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

KRT19 GLB1L3 RIPK4 MDFI SRGAP3 PLCH2

1.46e-0519611963b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCP AGBL4 PTPN13 SRGAP3 PKHD1 CACNA2D3

1.46e-0519611966ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCP AGBL4 PTPN13 SRGAP3 PKHD1 CACNA2D3

1.46e-051961196eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellmild_COVID-19-cDC|World / disease group, cell group and cell class (v2)

FNIP2 ANKRD65 ZNF503 FBLN2 SRGAP3 CACNA2D3

1.50e-05197119663e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLG KRT19 RIPK4 MDFI KRT23 PKP3

1.50e-051971196ac9c0c25cfeaabd53d332982c73fc6c47b0c6478
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLG KRT19 RIPK4 MDFI KRT23 PKP3

1.50e-051971196b57d2e3413ef6dd1da56c45087926f2f3eab876c
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT19 CYP4B1 RIPK4 MDFI SRGAP3 PKP3

1.50e-0519711965d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 GLB1L3 CYP4B1 RIPK4 SRGAP3 PLCH2

1.50e-051971196de772bd2b4cda843777ac879b1087e6444199dfb
ToppCellmild_COVID-19-cDC|mild_COVID-19 / disease group, cell group and cell class (v2)

FNIP2 ANKRD65 ZNF503 FBLN2 SRGAP3 CACNA2D3

1.50e-05197119644ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCell3'-Broncho-tracheal-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT19 CYP4B1 RIPK4 MDFI SRGAP3 PKP3

1.55e-051981196aa6e7218ee6230902854e66c444b544218b30c0e
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 PTPN13 PKP3

1.55e-05198119653e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KRT19 CYP4B1 COL27A1 ESRP2 PTPN13 ZFP36L1

1.55e-0519811961fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 PTPN13 PKP3

1.55e-05198119682bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCellmedial-Epithelial-Basal|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 GLB1L3 CYP4B1 RIPK4 MDFI PKP3

1.59e-051991196fa7584e3cc0f8cbdd6a76c6a0faee26b0922c4ae
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA10 ISLR ADGRA2 ANKRD53 FBLN2 PODN

1.59e-051991196dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellcellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT19 RIPK4 MDFI SRGAP3 PKP3 PLCH2

1.59e-051991196974f71b56f66243c78f2f297a1540e0e186df530
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLX ISLR MDFI ZNF503 ZFP36L1 CACNA2D3

1.59e-051991196a95aa72387c9558e0316898eaa9df4de8932af1b
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 PTPN13 PKP3

1.59e-0519911965b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCellmedial-Epithelial-Basal-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 GLB1L3 CYP4B1 RIPK4 MDFI PKP3

1.59e-051991196fc37f8868417308fb4410684d0d1e506cec30f35
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLX ISLR MDFI ZNF503 ZFP36L1 CACNA2D3

1.59e-051991196bb201deb281619113edcd1de2af2d3eb21b967b8
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANKRD13B ISLR TEK FBLN2 HOXC8 PODN

1.59e-05199119607b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 PTPN13 PKP3

1.59e-051991196bb2e839197b9a44b632c1bb716e48d885a1c8713
ToppCellmedial-2-Epithelial-Basal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 GLB1L3 CYP4B1 RIPK4 MDFI PKP3

1.59e-05199119610af93596cc6d5da4cf5052707ff5f7fc347dc84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA10 ISLR ADGRA2 ANKRD53 FBLN2 PODN

1.59e-051991196c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 CYP4B1 RIPK4 MDFI PKP3 PLCH2

1.64e-052001196afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GALE KRT19 CYP4B1 FOXP4 PTPN13 PKP3

1.64e-052001196c89f3cb36bb14c476d6a392bfd3ded1c8feecfeb
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD65 KRT19 CYP4B1 RIPK4 PTPN13 PKP3

1.64e-052001196d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABL1 CYP4B1 ISLR FBLN2 ZFP36L1 PODN

1.64e-052001196db6281b5d4032116310db379d9175d790994c99c
ToppCellproximal-3-Epithelial-Proximal_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 RIPK4 CDCA7 SRGAP3 PKP3 PLCH2

1.64e-0520011963a0c84f9a551fc2581ec3693481eada297d83f7b
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT19 CYP4B1 FOXP4 PKP3 PKHD1 CACNA2D3

1.64e-0520011968683445ad5b70748c4a1f12eb77d47623085147e
ToppCellproximal-Epithelial-Proximal_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 RIPK4 CDCA7 SRGAP3 PKP3 PLCH2

1.64e-052001196de9aec87c86ad0a1bd5e0737c2aae0ec6f269bca
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ZNF48 KRT19 RMDN1 PODN LIPT2 DNAH6

1.64e-0520011964db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ZNF48 KRT19 RMDN1 PODN LIPT2 DNAH6

1.64e-052001196d46a19274c2836ce7494790ce513764dedcadc79
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 GLB1L3 RIPK4 NEUROD2 SRGAP3 PLCH2

1.64e-0520011968827653738a931e4a4545e0c7d75be12bed40740
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

KIF26A EMID1 SORCS1 FBLN2 TMEM132E PODN

1.64e-05200119616a3685c41194a0a4a772e4eee372160263480e0
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / Treatment groups by lineage, cell group, cell type

KRT19 CYP4B1 FOXP4 PKP3 PKHD1 CACNA2D3

1.64e-0520011969a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCellParenchymal-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD65 KRT19 CYP4B1 FASN PTPN13 PKP3

1.64e-0520011964e5b6cb014d9bcb58e13c7511c86c43e27c496e4
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT19 CYP4B1 RIPK4 KRT23 PKP3 PLCH2

1.64e-052001196ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCellBiopsy_Other_PF-Epithelial-Basal|Biopsy_Other_PF / Sample group, Lineage and Cell type

KRT19 GLB1L3 CYP4B1 RIPK4 SRGAP3 PLCH2

1.64e-0520011967098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCellproximal-Epithelial-Proximal_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 RIPK4 CDCA7 SRGAP3 PKP3 PLCH2

1.64e-052001196ff2afa5c0352c214525129f9ff85afc139fe44d2
ToppCelldistal-2-Epithelial-Basal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT19 GLB1L3 CYP4B1 MDFI ESRP2 PKP3

1.64e-0520011969beb128841c50241aa819261f21bf66f881ea125
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXK2 ADGRA2 FOXP4 HOXC8 TMEM143

2.81e-0513211954152529611eeacf0c547e2a134d5b98c45426b13
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

B3GNT4 ERN1 DDN GRIN2C SLC4A10

3.99e-0514211951175d4390d204ffa3a2d2fe24486f85d3b639b72
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

ITGA10 C1RL PTPN13 CDCA7 SLC4A10

4.71e-0514711954ba9a86ab7033688a9a2a2dc84c001a49af835b4
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

ERN1 CASK PTPN13 CDCA7 SLC4A10

5.69e-051531195d09bc7322b59f613d66673359ee6af1aea99ce87
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4B1 ODAD1 KL SALL2 STOML1

5.87e-051541195dcbc6705e91ec744801b621e5d0733a78a7a90ca
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TEK CASK SORCS1 FBLN2 KCNB1

6.06e-05155119577fdae85d36efb776db977eb424b32487ef222e4
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KRT19 CYP4B1 RIPK4 PKP3 PKHD1

6.43e-0515711959665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKRD65 GDPD3 ZNF503 KCNB1 CACNA2D3

6.43e-051571195f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANKRD65 GDPD3 ZNF503 KCNB1 CACNA2D3

6.43e-05157119514a8516346a89a89f1119b744625bd9844a74a03
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ISLR MDFI KL FBLN2 PODN

6.83e-051591195cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LILRB2 HLX ADGRA2 FBLN2 SLC4A10

7.04e-051601195c9fe3438f747e2a98e3f27a56ba4c12a3789c2f2
DrugMCI-176

CASC3 PFKM GRAP2

4.68e-0671183CID000063181
Druggeldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA

CEBPA BICRA RIPK4 MAP3K12 ESRP2 JUNB ZFP36L1 BAHCC1

7.61e-061931188864_DN
Drug3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A

ERN1 SPTLC2 ITGA10 SIRT3 HOXC8 ZFP36L1 STOML1 RBM34

8.52e-0619611885624_DN
DrugPenbutolol sulfate [38363-32-5]; Down 200; 5.8uM; HL60; HT_HG-U133A

SPTLC2 ITGA10 DDN MAP3K12 CASK ZFP36L1 STOML1 C1orf159

8.84e-0619711882972_DN
DrugS(-)-terguride hydrogen maleate [37686-85-4]; Up 200; 8.8uM; HL60; HT_HG-U133A

SPTLC2 BICRA GDPD3 DDN CASK SALL2 PKP3 ARAP1

9.52e-0619911883096_UP
DiseaseIntellectual Disability

GALE APC2 GRIN2D CIC KCNK4 FASN ERLIN2 SRGAP3 SLC4A10 ACIN1

1.12e-0544711610C3714756
Diseasecomplex cortical dysplasia with other brain malformations (is_implicated_in)

KIF26A APC2

9.15e-0541162DOID:0090131 (is_implicated_in)
Diseasespecific developmental disorder (implicated_via_orthology)

FOXP4 FOXP3

9.15e-0541162DOID:0060038 (implicated_via_orthology)
Diseaseglycogen storage disease (implicated_via_orthology)

PFKL PFKM

9.15e-0541162DOID:2747 (implicated_via_orthology)
DiseaseMental Retardation, Psychosocial

CIC FASN ERLIN2 SRGAP3 SLC4A10

2.28e-041391165C0025363
DiseaseProfound Mental Retardation

CIC FASN ERLIN2 SRGAP3 SLC4A10

2.28e-041391165C0020796
DiseaseMental deficiency

CIC FASN ERLIN2 SRGAP3 SLC4A10

2.28e-041391165C0917816
Diseaseoctanoylcarnitine measurement

FNIP2 COL27A1

5.42e-0491162EFO_0021042
DiseasePathological accumulation of air in tissues

CEBPA KL

9.86e-04121162C0013990
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

PDZD7 TMEM132E

1.16e-03131162C1846647
Diseaserevision of total hip arthroplasty

RIPK4 VWA7

1.35e-03141162EFO_0020973
Diseasecolorectal cancer (is_implicated_in)

ABL1 POT1 PTPN13 FOXP3

1.35e-031211164DOID:9256 (is_implicated_in)
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

JUNB PTPN13

1.56e-03151162DOID:5520 (is_implicated_in)
DiseaseTinnitus

PTPN13 CDCA7 PKHD1 CACNA2D3

1.76e-031301164HP_0000360
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

CASK NEUROD2

1.77e-03161162C0393706
Diseaselifestyle measurement, anxiety disorder measurement

FOXK2 CEBPA SORCS1 UNC5D

2.13e-031371164EFO_0007795, EFO_0010724
Diseaseasthma

FLG CEBPA DNAAF9 VWA7 FBLN2 NEUROD2 ZFP36L1 CDCA7 SRGAP3

2.90e-037511169MONDO_0004979
Diseasedisease of metabolism (implicated_via_orthology)

PFKL PFKM

3.06e-03211162DOID:0014667 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

FLNB ABL1 APC2 GRIN2D TEK CIC SORCS1 FOXP4 FASN SRGAP3 FOXP3

3.42e-03107411611C0006142
DiseaseOvarian Serous Adenocarcinoma

ERN1 TEK

3.67e-03231162C1335177

Protein segments in the cluster

PeptideGeneStartEntry
HPRTSGGTRGVLSGN

ACIN1

6

Q9UKV3
FPGISSTDRGGLRGH

PABPN1L

226

A6NDY0
STDRGGLRGHPGSRG

PABPN1L

231

A6NDY0
AFKGGGGPRSTHALD

BAHCC1

736

Q9P281
PTGASDHFLGRRGSP

BAHCC1

2111

Q9P281
SAFPREVGGAGAGLH

ADGRA2

756

Q96PE1
LADHAGSGRRSGPSP

CLK3

11

P49761
EGQDTIRGHPGSSRG

FLG

511

P20930
DGQDTIRGHPGSSRG

FLG

2781

P20930
GRSEPSAFLRGHGSR

DENND2B

261

P78524
SSRLLHQPGGGRGGE

DDN

516

O94850
DSPFNSDRGGRGHGL

DNAJB8

116

Q8NHS0
SGPDGATGRGQRIHL

RAB27A

56

P51159
SLFRGEHHSRGGTGR

RBM34

41

P42696
SHRGGELGISLRPDG

PBLD

256

P30039
TFGSGGHLSLGRLLA

CAPN15

856

O75808
RPSSGPGSGGHVFRS

ANKRD13B

571

Q86YJ7
SSFLEVRPDGHGGAR

ANKRD53

421

Q8N9V6
RAPGFGRSGGHSLSP

PODN

26

Q7Z5L7
ESGLVAGGRVGTPHF

CASK

171

O14936
FRAPSIHGGSGGRGV

KRT19

31

P08727
AHLAGEAGSRIPGLG

PNLIPRP3

171

Q17RR3
SLLTGGRPAGVHLSG

HLX

201

Q14774
AEGFRNTLRGLGTPH

LPAR5

301

Q9H1C0
PGGTFQGRDLRGGAH

FOXP3

41

Q9BZS1
SRRHLEIFTPPGGGG

FOXK2

76

Q01167
AGVGDRLGSSLRHGI

KCNK4

136

Q9NYG8
VGLGTESTGRGKPHF

GLB1L3

66

Q8NCI6
RGRGHVGSVLGGLAS

LMAN1L

116

Q9HAT1
TPGEGGEDTLGRRFH

ISLR

346

O14498
LAAGGHRGLDGLPTT

FBLN2

296

P98095
GPGLHGGIVGRSADF

FLNB

556

O75369
ASRRGTHGGLVTGLP

IRF2BPL

226

Q9H1B7
RLGFSVRGGSEHGLG

PDZD7

96

Q9H5P4
LGHVQRGGTPSAFDR

PFKL

296

P17858
LGHVQRGGTPSAFDR

PFKM

296

P08237
GGRTPHDLFSSGLFR

MEGF8

351

Q7Z7M0
APTVHGGAGGARISL

KRT23

31

Q9C075
TGSDPQSGLGRHLGV

LILRB2

446

Q8N423
RVHELSASGAPGRGG

KIF26A

1566

Q9ULI4
TFRIRLGAHRGGSGE

GDPD3

36

Q7L5L3
GLGSASLHGGGPARR

FOXP4

426

Q8IVH2
GHGPTVGLLLSRGAS

ANKRD65

346

E5RJM6
DHLRGQAGFFSTPGG

EXOC8

131

Q8IYI6
RVPHDLLGGSGGFTL

FAAP100

206

Q0VG06
SRDRGSLGHVTFGGL

ODAD1

551

Q96M63
RGGALLTSTSGPGFH

ERLIN2

36

O94905
AARAGPPGGRSLHSS

NDUFS8

16

O00217
SGDLGGKFSIHPRLG

DCHS2

916

Q6V1P9
RFEGGHGPSGAAIRF

PCF11

916

O94913
GLLGGGSVTPRVHSA

MAML2

21

Q8IZL2
HNAFRGGGSLPESLR

GALE

36

Q14376
HEGLGVAVGGFPASR

APC2

2246

O95996
HTGIGKRGLFGTRSS

DNAH6

151

Q9C0G6
VRVLPGGGAHGSTRD

KCNB1

841

Q14721
GSLPSQRGGRTGALH

CASC3

46

O15234
PSAAHQGRGGRSGLL

B3GNT4

6

Q9C0J1
GRHSFSRRSGVPGTE

ERN1

721

O75460
QGLRDARGGPSHSAG

ANKZF1

246

Q9H8Y5
GTPFSLGVALSRGHG

CACNA2D3

611

Q8IZS8
LGAAHPDLRASGGSG

CEBPA

256

P49715
TASHGAGGTGGRRLE

FNIP2

821

Q9P278
PRQAGHGGTATDTGR

LINC02875

216

Q86X59
FTSIHGRGGGALLGD

C1RL

261

Q9NZP8
GTGRRFLGGLLDHTS

AGBL4

381

Q5VU57
GHLVRSTGPGGSFAK

DNAAF9

311

Q5TEA3
GALRESGGSGFRSPH

ABL1

671

P00519
AGERGHLGSRGFPGI

COL27A1

1101

Q8IZC6
HPSELGGTRRAGNGA

MDFI

106

Q99750
SGRGGSRAGSQHLTP

MAP3K12

686

Q12852
SVGRSHALVYGPGGS

HOXC8

31

P31273
GFSQSHGGRPEAARL

ITGA10

256

O75578
CPTVSRSGGFFGHRG

CDC20B

476

Q86Y33
HGYATGRLAPGIRGS

KL

246

Q9UEF7
TFGRGDTGLGHRDSS

CYP4B1

196

P13584
GTGTPSLLRGKRGGH

EMID1

411

Q96A84
LAATTGPRAHIGGGA

CELSR3

46

Q9NYQ7
DRRSQGGPHLSGAVG

GRAP2

161

O75791
RPGETLLIHSGSGGV

FASN

1666

P49327
LVIRHGGAGGSPSVT

BICRA

1246

Q9NZM4
LLSSHRFSGAGSGGP

C1orf159

331

Q96HA4
LGSQHPFSAGGVGRS

SALL2

281

Q9Y467
SLPGSRGERPHSFGS

C8B

26

P07358
RVTGRGGLATFHGPG

LIPT2

81

A6NK58
RHISENSFGPSGGLR

PTPN13

1226

Q12923
RGTLAHAFAPGEGLG

MMP20

186

O60882
SGAASPGLFQAGHRR

NUMB

421

P49757
LHRAEASGGLGGLTR

TARS2

436

Q9BW92
HEPFRRGTGVDLGQG

RNF5

141

Q99942
LHAPDASGGCGGSRR

TMEM132E

236

Q6IEE7
LNGREHRSGEPVGSG

KCP

316

Q6ZWJ8
HGGTSYGRGIRVLPE

POT1

266

Q9NUX5
HGRGEAITLRFDGSP

SIPA1

651

Q96FS4
VSAGLRGSHGARGEP

SIRT3

46

Q9NTG7
HGGSLLTIEGTGLRG

PKHD1

1586

P08F94
GGTEGLLFVRHPDGR

ESRP2

386

Q9H6T0
FQGGHGPAATLLRRS

RIPK4

816

P57078
DRSLLGLGLPSGGFH

ARAP1

1286

Q96P48
GSFRGRHPLPGSDSQ

CDCA7

141

Q9BWT1
LHTVGGPGSARPRAF

CIC

341

Q96RK0
GPGSARPRAFSHSGV

CIC

346

Q96RK0
SSHRSRGVGGAVPGA

PKP3

256

Q9Y446
GGGFPRRHSVTLPSS

ZFP36L1

46

Q07352
RGHLVLTPFGIGDGR

ZNF48

591

Q96MX3
LAHSFLARRPGGTQG

TMEM143

371

Q96AN5
RRSGGDTHSPPRGLG

SRGAP3

866

O43295
SRLPAGTSGSRGHCG

RMDN1

21

Q96DB5
AHSIGALGPTGRGVV

SPTLC2

346

O15270
DLTTGRGRVGHGVPD

STOML1

331

Q9UBI4
GGSRRLSHSLGLPGG

PLCH2

1271

O75038
HSGPELQRTGRIFGG

SLC4A10

471

Q6U841
QARLGLGTEGSGRHG

SH2D7

251

A6NKC9
GEGHPGPVRRFTTAS

TEK

526

Q02763
ELRTTGVFGHLGGRL

UNC5D

541

Q6UXZ4
RGHLGNGDRPSAGAT

nan

66

Q8N1X5
SAEGGPTGLAHGRIS

ZNF503

271

Q96F45
LPSTRGGRRSGHGAV

nan

111

Q6ZS52
VASSHSPAGGFPRGR

nan

201

Q5PR19
HTTPVGDGAAGTRGL

TMEM41B

16

Q5BJD5
STPRGFSHQGRPGRA

SORCS1

51

Q8WY21
PLLLFSHREGGGRGA

nan

26

Q6ZS46
GGHFDRSSSQPPRGG

VWA7

246

Q9Y334
QEEGGGPLGHTRRFG

VWA7

551

Q9Y334
LAVGTGRFSGPLHRA

TMEM251

16

Q8N6I4
TATGYGRAPGGLSLH

JUNB

16

P17275
LHPGVSSRFSGRGSG

IGKV1D-42

76

A0A075B6H8
RPTGHGLVFGSSAVR

NEUROD2

336

Q15784
GHRGRTLGLGTGYRD

GRIN2C

1186

Q14957
RGGDLGTRRGSAHFS

GRIN2D

1316

O15399