Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-membrane adaptor activity

ATG16L1 SYNE3 ATG14

2.06e-0445513GO:0043495
GeneOntologyMolecularFunctionS-methyltransferase activity

ASMT MTR

3.47e-0411512GO:0008172
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH9

9.53e-0418512GO:0008569
GeneOntologyMolecularFunctionmethyltransferase activity

EED ASMT MTR METTL6

2.13e-03213514GO:0008168
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH9

2.32e-0328512GO:0051959
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

EED ASMT MTR METTL6

2.55e-03224514GO:0016741
GeneOntologyCellularComponentaxoneme

ATG16L1 DNAH2 ATG14 TTLL10 DNAH9

1.62e-04207525GO:0005930
GeneOntologyCellularComponentciliary plasm

ATG16L1 DNAH2 ATG14 TTLL10 DNAH9

1.65e-04208525GO:0097014
GeneOntologyCellularComponenttransferase complex

ATG16L1 EED FBXO31 KAT8 ATG14 PRKDC MED27 QTRT1 DCAF4

5.55e-04963529GO:1990234
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

ATG16L1 DNAH2 ATG14 TTLL10 DNAH9

1.13e-03317525GO:0032838
GeneOntologyCellularComponentphagophore assembly site membrane

ATG16L1 ATG14

1.36e-0322522GO:0034045
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH9

1.76e-0325522GO:0005858
GeneOntologyCellularComponentcytoplasmic region

ATG16L1 DNAH2 ATG14 TTLL10 DNAH9

1.97e-03360525GO:0099568
DomainATPase_dyneun-rel_AAA

MDN1 DNAH2 DNAH9

7.25e-0614523IPR011704
DomainAAA_5

MDN1 DNAH2 DNAH9

7.25e-0614523PF07728
DomainDynein_heavy_dom-1

DNAH2 DNAH9

2.11e-048522IPR013594
DomainDHC_N1

DNAH2 DNAH9

2.11e-048522PF08385
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH9

6.77e-0414522IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH9

6.77e-0414522IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH9

6.77e-0414522IPR013602
DomainDHC_N2

DNAH2 DNAH9

6.77e-0414522PF08393
DomainMT

DNAH2 DNAH9

6.77e-0414522PF12777
DomainAAA_8

DNAH2 DNAH9

6.77e-0414522PF12780
DomainDHC_fam

DNAH2 DNAH9

7.80e-0415522IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH9

7.80e-0415522IPR004273
DomainDynein_heavy

DNAH2 DNAH9

7.80e-0415522PF03028
DomainWD40

PWP1 ATG16L1 EED DCAF4

5.81e-03259524PF00400
DomainWD40

PWP1 ATG16L1 EED DCAF4

6.54e-03268524SM00320
DomainF-box-like

FBXO31 FBXO41

6.67e-0344522PF12937
DomainWD40_repeat

PWP1 ATG16L1 EED DCAF4

6.89e-03272524IPR001680
DomainWD_REPEATS_1

PWP1 ATG16L1 EED DCAF4

7.43e-03278524PS00678
DomainWD_REPEATS_2

PWP1 ATG16L1 EED DCAF4

7.52e-03279524PS50082
DomainWD_REPEATS_REGION

PWP1 ATG16L1 EED DCAF4

7.52e-03279524PS50294
DomainAAA+_ATPase

MDN1 DNAH2 DNAH9

7.53e-03144523IPR003593
DomainAAA

MDN1 DNAH2 DNAH9

7.53e-03144523SM00382
Pubmed

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.

ATG16L1 ATG14 PRKDC

5.47e-071153328973896
Pubmed

Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.

KLF7 KLF6 KLF1

7.28e-071253315937668
Pubmed

A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence.

ATG16L1 ATG14

6.83e-06353230335568
Pubmed

Mammalian SP/KLF transcription factors: bring in the family.

KLF7 KLF6 KLF1

7.51e-062553315820306
Pubmed

The histone chaperone ASF1 regulates the activation of ATM and DNA-PKcs in response to DNA double-strand breaks.

KAT8 PRKDC

1.36e-05453229954236
Pubmed

Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina.

GSTT1 MTR

3.40e-05653217450230
Pubmed

The parasitophorous vacuole membrane of Toxoplasma gondii is targeted for disruption by ubiquitin-like conjugation systems of autophagy.

ATG16L1 ATG14

3.40e-05653224931121
Pubmed

Polymorphisms in genes involved in DNA repair and metabolism of xenobiotics in individual susceptibility to sporadic diffuse gastric cancer.

GSTT1 MTR

4.76e-05753217617021
Pubmed

Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation.

ATG16L1 ATG14

4.76e-05753223878278
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH9

4.76e-05753231178125
Pubmed

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

ATG16L1 ATG14

6.34e-05853230853401
Pubmed

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

ATG16L1 ATG14

6.34e-05853223262492
Pubmed

HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins.

EED PRKDC

6.34e-05853215875659
Pubmed

Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design.

EED PRKDC

6.34e-05853216075307
Pubmed

Variable drug metabolism genes in Arab population.

GSTT1 MTR

6.34e-05853215111988
Pubmed

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.

ATG16L1 ATG14

8.15e-05953226649827
Pubmed

The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy.

ATG16L1 ATG14

8.15e-05953225825496
Pubmed

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.

ATG16L1 ATG14

1.02e-041053226764600
Pubmed

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.

ATG16L1 ATG14

1.02e-041053221220506
Pubmed

Connexins modulate autophagosome biogenesis.

ATG16L1 ATG14

1.02e-041053224705551
Pubmed

Pharmacogenetic analyses of a phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil and leucovorin plus either oxaliplatin or cisplatin: a study of the arbeitsgemeinschaft internistische onkologie.

GSTT1 MTR

1.24e-041153219332728
Pubmed

Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: impact of air pollution and genetic polymorphisms.

GSTT1 MTR

1.24e-041153220723587
Pubmed

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.

ATG16L1 ATG14

1.24e-041153226764599
Pubmed

Functional interaction between autophagy and ciliogenesis.

ATG16L1 ATG14

1.24e-041153224089209
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

MYO1G EED SYNE3 MDN1 PRKDC

1.69e-0434053529478914
Pubmed

IRGM governs the core autophagy machinery to conduct antimicrobial defense.

ATG16L1 ATG14

1.76e-041353225891078
Pubmed

Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemia.

GSTT1 MTR

1.76e-041353219774638
Pubmed

Chromosomal aberrations in railroad transit workers: effect of genetic polymorphisms.

GSTT1 MTR

2.05e-041453219177501
Pubmed

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

ATG16L1 ATG14

2.36e-041553230245008
Pubmed

Identification of potential protein interactors of Lrrk2.

MDN1 PRKDC

2.36e-041553217400507
Pubmed

Pharmacogenetic analyses of hematotoxicity in advanced gastric cancer patients receiving biweekly fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a translational study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

GSTT1 MTR

2.36e-041553219074750
Pubmed

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

KAT8 PRKDC

3.05e-041753220479123
Pubmed

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.

MTR C1orf167

4.25e-042053223824729
Pubmed

Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2.

KLF1 MTR

5.16e-042253226166573
Pubmed

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

ATG16L1 ATG14

5.16e-042253228890335
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

MELTF SYNE3 ARHGAP10 PXDC1 GFRA3 METTL6

6.02e-0468653629987050
Pubmed

Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival.

ATG16L1 ATG14

9.01e-042953236198274
Pubmed

Multimodal Hox5 activity generates motor neuron diversity.

KLF7 KLF6

9.01e-042953239289460
Pubmed

A pancreatic cancer-specific expression profile.

PWP1 MED27

1.10e-03325328895530
Pubmed

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

GSTT1 MTR

1.10e-033253220437058
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

LRIG3 AMIGO2

1.24e-033453218848646
Pubmed

Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.

GSTT1 MTR

1.31e-033553218992148
GeneFamilyZinc fingers C2H2-type|Kruppel like factors

KLF7 KLF6 KLF1

7.40e-0618393624
GeneFamilyDyneins, axonemal

DNAH2 DNAH9

6.04e-0417392536
GeneFamilyAutophagy related

ATG16L1 ATG14

2.29e-03333921022
GeneFamilyWD repeat domain containing

PWP1 ATG16L1 EED DCAF4

2.38e-03262394362
GeneFamilyCyclins|F-boxes other

FBXO31 FBXO41

3.19e-0339392560
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP23 ARHGAP10

5.20e-0350392721
GeneFamilyProteases, serine

TMPRSS9 PRSS50

8.15e-0363392738
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RGS22 DNAH2 CC2D2A TTLL10 DNAH9

2.72e-061855355e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RGS22 DNAH2 CC2D2A TTLL10 DNAH9

2.80e-0618653576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

RGS22 DNAH2 CC2D2A TTLL10 DNAH9

3.35e-06193535aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RGS22 DNAH2 CC2D2A TTLL10 DNAH9

3.43e-061945351ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RGS22 DNAH2 CC2D2A TTLL10 DNAH9

3.61e-0619653527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

2.98e-051495346399c5a2f06d79f020dece252526f1c0c110d569
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

MYO1G RAMP1 SYT17 DNAH2

3.94e-05160534bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KLF1 DNAH2 TTLL10 GFRA3

4.34e-05164534b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RAMP1 ARHGAP23 SYT17 DNAH2

4.34e-0516453467c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EYS RGS22 DNAH2 DNAH9

4.34e-051645349e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KLF1 DNAH2 TTLL10 GFRA3

4.34e-05164534f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MYO1G ARHGAP23 SYT17 DNAH2

4.44e-051655349d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 KLF1 PRSS50 SIX3

4.55e-051665348d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 KLF1 PRSS50 SIX3

4.55e-05166534f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 KLF1 PRSS50 SIX3

4.55e-05166534a5074c96c6561273029aceb93402a7e038140f50
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNK1 LRIG3 PRSS50 MTR

4.76e-051685342e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMPRSS9 RAMP1 FBXO31 FBXO41

4.87e-0516953496aafb687b34d4b59f75c24e176b0b442e864245
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INSL5 DNAH2 TTLL10 DNAH9

5.34e-05173534c3762655caa79ac4879876f470d32578a3c93b01
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATG16L1 RAMP1 DNAH9 AMIGO2

5.34e-051735345295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

5.58e-051755344d36da7399c62c170cb603957b35a35efb2c3fbe
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

5.58e-051755342c39c1b112e873403ad2add8595cc256bf0b97a6
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

5.58e-05175534e4c9b3c6bde390a3892b112b673f93e118220eb9
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

5.96e-05178534255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

6.09e-051795347329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

6.09e-051795346e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 TMPRSS9 SYNE3 KLF1

6.09e-05179534ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

6.50e-051825347ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

RGS22 DNAH2 TTLL10 DNAH9

6.50e-05182534fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

6.50e-05182534e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSL5 DNAH9 GFRA3 AMIGO2

6.50e-05182534398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

6.78e-051845345daff849625f2f41d56615569c0ed59cd733b34c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

6.92e-0518553430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

6.92e-051855344fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

RGS22 DNAH2 TTLL10 DNAH9

6.92e-0518553418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

6.92e-05185534f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

7.07e-05186534f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CC2D2A TTLL10 DNAH9

7.07e-0518653485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.22e-051875349e10ed56090d82589bc457788282f664b70ace4b
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

RGS22 CC2D2A TTLL10 DNAH9

7.22e-051875341a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

7.22e-05187534e61992de4f98eeea08b43213850769d923f8db48
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

7.22e-05187534bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.37e-0518853434b11f72ca73153d02edcd09b38983ad1a504659
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 KLF1 ASMT PRSS50

7.37e-051885341a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

7.37e-05188534606907c865bd2f11bb6474932716550f7723d858
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.37e-0518853461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.37e-051885342b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

RGS22 DNAH2 TTLL10 DNAH9

7.37e-05188534803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

RGS22 DNAH2 TTLL10 DNAH9

7.37e-051885349a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGS22 DNAH2 TTLL10 DNAH9

7.52e-05189534a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RGS22 DNAH2 TTLL10 DNAH9

7.52e-0518953457ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RGS22 DNAH2 TTLL10 DNAH9

7.52e-05189534ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.52e-0518953468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RGS22 DNAH2 TTLL10 DNAH9

7.52e-05189534a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

KLF7 KLF6 ARHGAP10 MTR

7.52e-05189534a48df46274d51e84ffb40264646de7346104efb9
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

RGS22 DNAH2 TTLL10 DNAH9

7.52e-05189534b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

RGS22 DNAH2 TTLL10 DNAH9

7.52e-0518953427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

KLF1 PRSS50 DCAF4 AMIGO2

7.52e-0518953437d2c45debed1564a40a1085b8b310c50923b9e7
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RGS22 DNAH2 TTLL10 DNAH9

7.52e-0518953493b1026bb1ba759e5704561c9a5de14a30c08894
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

7.68e-05190534426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

RGS22 DNAH2 TTLL10 DNAH9

7.68e-05190534169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

RGS22 DNAH2 TTLL10 DNAH9

7.68e-051905340cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

RGS22 DNAH2 TTLL10 DNAH9

7.68e-051905347031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RGS22 DNAH2 TTLL10 DNAH9

7.68e-0519053417829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAMP1 UGT2A1 TTLL10 SIX3

7.68e-051905342fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RGS22 DNAH2 TTLL10 DNAH9

7.83e-051915342a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

RGS22 DNAH2 TTLL10 DNAH9

7.83e-051915342d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RGS22 DNAH2 TTLL10 DNAH9

7.83e-0519153446c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

RGS22 DNAH2 TTLL10 DNAH9

7.83e-05191534995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RGS22 DNAH2 TTLL10 DNAH9

7.83e-05191534a37f20172b85566b9039254a89680e37fd503fd5
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

RGS22 DNAH2 TTLL10 DNAH9

7.99e-05192534097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellLAM-Epithelial-AirwayEpi|LAM / Condition, Lineage and Cell class

RGS22 DNAH2 TTLL10 DNAH9

7.99e-051925347404fc65be3b7bd09447725b43fa31819004dfee
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

RGS22 DNAH2 TTLL10 DNAH9

7.99e-051925349cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

SYT17 RGS22 DNAH2 DNAH9

7.99e-05192534354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

RAMP1 RGS22 TTLL10 DNAH9

8.15e-051935343e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 CC2D2A TTLL10 DNAH9

8.15e-05193534e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

RGS22 CC2D2A TTLL10 DNAH9

8.32e-051945347a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.32e-051945344a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRIG3 ARHGAP23 UGT2A1 SIX3

8.32e-051945342932f704656ca368565ec12f3452af3b18e8df12
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

RGS22 CC2D2A TTLL10 DNAH9

8.32e-05194534b4ce60c06568123008b1081d644733cb91c28f51
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

RGS22 DNAH2 TTLL10 DNAH9

8.32e-0519453443be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RGS22 DNAH2 TTLL10 DNAH9

8.49e-05195534d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 CC2D2A TTLL10 DNAH9

8.49e-051955343486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 CC2D2A TTLL10 DNAH9

8.49e-05195534e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RGS22 CC2D2A TTLL10 DNAH9

8.49e-0519553407a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RGS22 DNAH2 TTLL10 DNAH9

8.49e-05195534e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.65e-05196534a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RAMP1 CC2D2A TTLL10 DNAH9

8.65e-051965349a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.65e-0519653489ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.65e-05196534a156840330630e518bc85633dded6f2c3ead3b30
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 CC2D2A TTLL10 DNAH9

8.65e-05196534d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.65e-05196534009e83c7251cf300be78b263634d233a8d972a68
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RGS22 CC2D2A TTLL10 DNAH9

8.83e-051975346865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 DNAH2 TTLL10 DNAH9

8.83e-0519753474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 CC2D2A TTLL10 DNAH9

9.00e-05198534ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RGS22 DNAH2 TTLL10 DNAH9

9.18e-05199534542ec45c931b40738df1f3777b00c83be33a514a
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RGS22 DNAH2 TTLL10 DNAH9

9.18e-051995342498237b9e895ca4826a3378d9d40989968df72b
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RGS22 DNAH2 TTLL10 DNAH9

9.36e-052005349c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RGS22 DNAH2 TTLL10 DNAH9

9.36e-0520053452aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RGS22 DNAH2 TTLL10 DNAH9

9.36e-0520053412bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellSigmoid-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

ATG16L1 SYNE3 RAMP1 FBXO31

9.36e-0520053409deb831fc2c8a8867cc850f3aa094a5e48489ff
DiseaseHematological Disease

KLF1 MTR

8.15e-058512C0018939
Diseaseceramide measurement

LRIG3 EYS MDN1 TTLL10

7.31e-04235514EFO_0010222
Diseasecerebral white matter volume change measurement, age at assessment

NOCT FRMD4B

1.08e-0328512EFO_0008007, EFO_0021499
Diseaseresting heart rate

ARHGAP10 FRMD4B GFRA3

2.20e-03149513EFO_0004351
Diseasehomocysteine measurement

MTR C1orf167

2.89e-0346512EFO_0004578
Diseaseglucose metabolism measurement, age-related hearing impairment

LRIG3 RAMP1

3.68e-0352512EFO_0005782, EFO_0009367
Diseaseeosinophil count

MELTF RAMP1 MDN1 KLF7 SYT17 ATG14 PRKDC DCAF4

3.78e-031488518EFO_0004842
Diseaseacute lymphoblastic leukemia (is_implicated_in)

GSTT1 MTR

4.10e-0355512DOID:9952 (is_implicated_in)
Diseasemultiple myeloma (is_implicated_in)

GSTT1 MTR

4.71e-0359512DOID:9538 (is_implicated_in)
DiseaseHallux valgus

EYS MTR

4.86e-0360512HP_0001822

Protein segments in the cluster

PeptideGeneStartEntry
SWRHIRAEGLDCSYT

ALKBH2

56

Q6NS38
CYTRIWSLHDARLLR

DCAF4

436

Q8WV16
LASHRAWDRTCRAVL

C1orf167

926

Q5SNV9
RRTTYLSGRWVCDDH

ATG14

241

Q6ZNE5
RIWTVDDYRLRHTLT

ATG16L1

391

Q676U5
NDYTCRLWSDSRHSR

AMIGO2

256

Q86SJ2
RTSYRCWGHLADAVR

ASMT

111

P46597
YWHRLCTCTDRRAEK

PKD1L1-AS1

96

Q9H7B7
RTIRSYRELADCTWH

RAMP1

61

O60894
CYLDSPWFRERIRAH

ARHGAP10

11

A1A4S6
LRSHDTLVRWYTANC

MDN1

176

Q9NU22
EYSADSLISRREHWR

EYS

1471

Q5T1H1
WVVIIYHTRRRNEDC

LRIG3

826

Q6UXM1
YLCRRPDSTWHSAEV

KAT8

61

Q9H7Z6
LHTDTIWRRRCREEY

FBXO31

101

Q5XUX0
TRDIHRNYVDCVRWL

EED

301

O75530
CEWRFARSDELTRHY

KLF7

256

O75840
WRDFRTLEAFHDTCR

MED27

296

Q6P2C8
TVIYICASSRWRRHQ

INSL5

36

Q9Y5Q6
HWTTREFEELRSCRE

METTL6

61

Q8TCB7
STLRRWYTERLRACH

FRMD4B

26

Q9Y2L6
WYTERLRACHQVLRT

FRMD4B

31

Q9Y2L6
CGWRFARSDELTRHY

KLF1

316

Q13351
LTRWNRYCTSTLRHF

CC2D2A

1516

Q9P2K1
VACLDIYWTVHRARS

GFRA3

111

O60609
TRTLLHAAEVCRDWR

FBXO41

566

Q8TF61
WSIRETLRYQRHASD

INO80D

346

Q53TQ3
GHITDDWDRRLCRTY

DNAH9

4116

Q9NYC9
ERYVTTVTSWCRRLT

C5orf34

526

Q96MH7
TRLWIHECFRVFSDR

DNAH2

2641

Q9P225
IRTSGECRHTLDYIW

NOCT

366

Q9UK39
DEYLAWQHTTLRRSC

GSTT1

96

P30711
IRTEWSDRSVLYLHR

PXDC1

41

Q5TGL8
YRSIRWLDRCIAAHQ

QTRT1

176

Q9BXR0
SRADVTEWRQCHLAR

MELTF

261

P08582
VEQWHSLRSRAECDR

SYT17

451

Q9BSW7
LVAHWRRYSATRAAL

SYNE3

371

Q6ZMZ3
RRLRATCHVVSDSWD

LRRC41

786

Q15345
SRADWCISHRTYDIG

RGS22

396

Q8NE09
LHERVRRELWAYCGS

MTR

1141

Q99707
HCFKERTRSLLREWY

SIX3

211

O95343
LYDCRSPDESHRMWR

PWP1

326

Q13610
WTELRRHEVTICNYE

PITHD1

176

Q9GZP4
WHRARSDDYLSRATR

ARHGAP23

346

Q9P227
IRWTSSLRRETSDYH

TMPRSS9

66

Q7Z410
SHRARVVLSWADYLR

SLC35C2

71

Q9NQQ7
WVQSYCRLSHCRSRS

PRKDC

3276

P78527
LSSRSRADCWRILEH

TNK1

636

Q13470
AYGWCSELIRHRRVH

ZNF232

396

Q9UNY5
VAHCLIWRDVIYSVR

PRSS50

151

Q9UI38
RFSRLSLHCSWDYRL

UGT2A1

266

P0DTE4
RIHDSRRDDYTLKWC

TTLL10

181

Q6ZVT0
GCEWRFARSDELTRH

KLF6

236

Q99612
CRRAWARDYLSSATD

MYO1G

831

B0I1T2