Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.63e-1826288GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.59e-1552288GO:0005272
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN10A KCNE2 PIEZO2 PKD1L2 PKDREJ SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.30e-143432812GO:0005261
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.37e-144652813GO:0046873
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN10A SLC6A7 SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.87e-141712810GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.61e-146642814GO:0008324
GeneOntologyMolecularFunctiontransmembrane transporter activity

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 ABCA6 PKDREJ SLC9C2 ABCA8 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.11e-1311802816GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN10A KCNE2 PIEZO2 PKD1L2 PKDREJ SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.11e-134592812GO:0005216
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.19e-137932814GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.20e-136272813GO:0022890
GeneOntologyMolecularFunctiontransporter activity

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 ABCA6 PKDREJ SLC9C2 ABCA8 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.21e-1212892816GO:0005215
GeneOntologyMolecularFunctionchannel activity

SCN10A KCNE2 PIEZO2 PKD1L2 PKDREJ SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.00e-125252812GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCN10A KCNE2 PIEZO2 PKD1L2 PKDREJ SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.04e-125262812GO:0022803
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.79e-127582813GO:0015318
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

7.38e-1214285GO:0031402
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

2.40e-1026285GO:0031420
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN10A SCN1A SCN2A

1.66e-0617283GO:0099508
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN10A SCN5A

2.83e-056282GO:0086006
GeneOntologyMolecularFunctiongated channel activity

SCN10A KCNE2 PIEZO2 SCN1A SCN2A

9.10e-05334285GO:0022836
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

SCN10A KCNE2 SCN1A SCN2A

1.15e-04182284GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

SCN10A KCNE2 SCN1A SCN2A

1.20e-04184284GO:0022832
GeneOntologyMolecularFunctioncalmodulin binding

WFS1 SCN2A SCN3A SCN5A

2.83e-04230284GO:0005516
GeneOntologyMolecularFunctiontransmembrane transporter binding

SCN10A KCNE2 SCN5A

1.76e-03172283GO:0044325
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA6 ABCA8

2.14e-0349282GO:0140359
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A7 ABCA6 SLC9C2 ABCA8

4.18e-03477284GO:0022804
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA6 ABCA8

1.02e-02109282GO:0042626
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.21e-1762289GO:0086002
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.13e-1636288GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.79e-1587289GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.33e-1593289GO:0086003
GeneOntologyBiologicalProcessneuronal action potential

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.41e-1463288GO:0019228
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.97e-14127289GO:0070252
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN10A SLC6A7 SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

9.81e-142082810GO:0035725
GeneOntologyBiologicalProcessactin filament-based movement

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.28e-13153289GO:0030048
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.28e-13167289GO:0060048
GeneOntologyBiologicalProcesssodium ion transport

SCN10A SLC6A7 SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.60e-122752810GO:0006814
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.66e-12112288GO:0019226
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 WFS1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.94e-1211572815GO:0006812
GeneOntologyBiologicalProcessmembrane depolarization

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.13e-12121288GO:0051899
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.45e-129422814GO:0098655
GeneOntologyBiologicalProcessaction potential

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.90e-12201289GO:0001508
GeneOntologyBiologicalProcessmetal ion transport

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 WFS1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.70e-1210002814GO:0030001
GeneOntologyBiologicalProcessstriated muscle contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

7.77e-12217289GO:0006941
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.30e-1111152814GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

SCN10A SLC6A7 KCNE2 PIEZO2 PKD1L2 PKDREJ SLC9C2 WFS1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.44e-1113742815GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.25e-119222813GO:0098662
GeneOntologyBiologicalProcessheart contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.32e-10298289GO:0060047
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SCN10A SLC6A7 KCNE2 PKD1L2 PKDREJ SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.77e-1010172813GO:0098660
GeneOntologyBiologicalProcessheart process

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.82e-10309289GO:0003015
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN10A PIEZO2 PKD1L2 PKDREJ SCN1A SCN9A

6.66e-1075286GO:0050982
GeneOntologyBiologicalProcessregulation of membrane potential

SCN10A KCNE2 PIEZO2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.67e-095592810GO:0042391
GeneOntologyBiologicalProcessmuscle contraction

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.77e-09400289GO:0006936
GeneOntologyBiologicalProcessmuscle system process

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.68e-08547289GO:0003012
GeneOntologyBiologicalProcessdetection of external stimulus

SCN10A PIEZO2 PKD1L2 PKDREJ SCN1A SCN9A

1.03e-07173286GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN10A PIEZO2 PKD1L2 PKDREJ SCN1A SCN9A

1.10e-07175286GO:0009582
GeneOntologyBiologicalProcessblood circulation

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.14e-07648289GO:0008015
GeneOntologyBiologicalProcesscirculatory system process

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.24e-07733289GO:0003013
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

SCN10A PIEZO2 WFS1 SCN1A SCN8A SCN9A

6.75e-07238286GO:0050954
GeneOntologyBiologicalProcessresponse to mechanical stimulus

SCN10A PIEZO2 PKD1L2 PKDREJ SCN1A SCN9A

8.38e-07247286GO:0009612
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN10A PIEZO2 SCN1A SCN9A

1.02e-0657284GO:0050974
GeneOntologyBiologicalProcessactin filament-based process

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.01e-06912289GO:0030029
GeneOntologyBiologicalProcessdetection of stimulus

SCN10A OR2T29 OR2T5 PIEZO2 PKD1L2 PKDREJ SCN1A SCN9A

3.62e-06722288GO:0051606
GeneOntologyBiologicalProcessbehavioral response to pain

SCN10A SCN3A SCN9A

1.08e-0532283GO:0048266
GeneOntologyBiologicalProcessbehavior

SCN10A CLSTN2 WFS1 SCN1A SCN2A SCN3A SCN8A SCN9A

1.69e-05891288GO:0007610
GeneOntologyBiologicalProcessmulticellular organismal response to stress

SCN10A KCNE2 SCN3A SCN9A

2.43e-05126284GO:0033555
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN10A SCN1A SCN9A

2.67e-0543283GO:0062149
GeneOntologyBiologicalProcessbundle of His cell action potential

SCN10A SCN5A

3.72e-057282GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

SCN10A SCN5A

3.72e-057282GO:0086028
GeneOntologyBiologicalProcessresponse to pain

SCN10A SCN3A SCN9A

4.47e-0551283GO:0048265
GeneOntologyBiologicalProcesssensory perception

SCN10A OR2T29 OR2T5 PIEZO2 WFS1 SCN1A SCN8A SCN9A

6.34e-051072288GO:0007600
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN10A SCN5A

7.94e-0510282GO:0060371
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

SCN10A OR2T29 OR2T5 PIEZO2 SCN1A SCN9A

1.09e-04582286GO:0050906
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

SCN10A SCN5A

1.16e-0412282GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

SCN10A SCN5A

1.16e-0412282GO:0086016
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

SCN10A SCN5A

1.85e-0415282GO:0086069
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

SCN10A SCN5A

1.85e-0415282GO:0086067
GeneOntologyBiologicalProcessimport across plasma membrane

SLC6A7 KCNE2 SLC9C2 SCN5A

2.50e-04230284GO:0098739
GeneOntologyBiologicalProcesscardiac conduction

SCN10A KCNE2 SCN5A

3.32e-04100283GO:0061337
GeneOntologyBiologicalProcesssensory perception of pain

SCN10A SCN1A SCN9A

3.83e-04105283GO:0019233
GeneOntologyBiologicalProcessnerve development

SCN1A SCN2A SCN8A

4.27e-04109283GO:0021675
GeneOntologyBiologicalProcessregulation of striated muscle contraction

SCN10A SCN4A SCN5A

4.50e-04111283GO:0006942
GeneOntologyBiologicalProcessregulation of ventricular cardiac muscle cell membrane repolarization

KCNE2 SCN5A

5.23e-0425282GO:0060307
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

SCN10A SCN9A

5.66e-0426282GO:0050965
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

SLC9C2 SCN5A

6.11e-0427282GO:0098719
GeneOntologyBiologicalProcessregulation of heart rate

SCN10A KCNE2 SCN5A

6.98e-04129283GO:0002027
GeneOntologyBiologicalProcessventricular cardiac muscle cell membrane repolarization

KCNE2 SCN5A

7.55e-0430282GO:0099625
GeneOntologyBiologicalProcessregulation of cardiac muscle cell membrane repolarization

KCNE2 SCN5A

7.55e-0430282GO:0099623
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception

SCN10A SCN9A

7.55e-0430282GO:0050961
GeneOntologyBiologicalProcesschemosensory behavior

WFS1 SCN9A

8.06e-0431282GO:0007635
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

SCN10A SCN1A

8.60e-0432282GO:0099505
GeneOntologyBiologicalProcessdetection of temperature stimulus

SCN10A SCN9A

9.14e-0433282GO:0016048
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

KCNE2 SLC9C2 SCN5A

9.23e-04142283GO:0098659
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

KCNE2 SLC9C2 SCN5A

9.23e-04142283GO:0099587
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

SCN10A SCN5A

9.71e-0434282GO:0086019
GeneOntologyBiologicalProcessventricular cardiac muscle cell action potential

KCNE2 SCN5A

1.15e-0337282GO:0086005
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

SCN10A SCN9A

1.21e-0338282GO:0050951
GeneOntologyBiologicalProcesscardiac muscle cell membrane repolarization

KCNE2 SCN5A

1.41e-0341282GO:0099622
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

KCNE2 SCN5A

1.41e-0341282GO:0086091
GeneOntologyBiologicalProcessregulation of membrane repolarization

KCNE2 SCN5A

1.41e-0341282GO:0060306
GeneOntologyBiologicalProcessresponse to abiotic stimulus

SCN10A PIEZO2 PKD1L2 PKDREJ SCN1A SCN2A SCN9A

1.86e-031361287GO:0009628
GeneOntologyBiologicalProcessadult walking behavior

SCN1A SCN8A

2.09e-0350282GO:0007628
GeneOntologyBiologicalProcessdetermination of adult lifespan

SCN1A SCN2A

2.43e-0354282GO:0008340
GeneOntologyBiologicalProcessregulation of muscle contraction

SCN10A SCN4A SCN5A

2.53e-03202283GO:0006937
GeneOntologyBiologicalProcessmembrane repolarization

KCNE2 SCN5A

2.62e-0356282GO:0086009
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

SCN10A SCN5A

2.90e-0359282GO:0086065
GeneOntologyBiologicalProcessregulation of proteasomal protein catabolic process

KCNE2 WFS1 CSNK2A2

2.94e-03213283GO:0061136
GeneOntologyBiologicalProcesswalking behavior

SCN1A SCN8A

3.00e-0360282GO:0090659
GeneOntologyBiologicalProcessregulation of membrane depolarization

SCN10A SCN5A

3.10e-0361282GO:0003254
GeneOntologyBiologicalProcessregulation of heart contraction

SCN10A KCNE2 SCN5A

4.56e-03249283GO:0008016
GeneOntologyBiologicalProcessregulation of proteolysis involved in protein catabolic process

KCNE2 WFS1 CSNK2A2

4.87e-03255283GO:1903050
GeneOntologyBiologicalProcessregulation of action potential

SCN5A SCN9A

5.39e-0381282GO:0098900
GeneOntologyBiologicalProcesspotassium ion transport

KCNE2 SLC9C2 SCN4A

5.82e-03272283GO:0006813
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

SCN10A SCN5A

6.47e-0389282GO:0055117
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

8.30e-2017288GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.45e-1729288GO:0034706
GeneOntologyCellularComponentcation channel complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.41e-11235289GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

9.59e-10378289GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.62e-08523289GO:1902495
GeneOntologyCellularComponenttransporter complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.50e-08550289GO:1990351
GeneOntologyCellularComponentplasma membrane protein complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.15e-07785289GO:0098797
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

2.42e-0620283GO:0033268
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

7.68e-0629283GO:0043194
GeneOntologyCellularComponentaxon

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.53e-05891288GO:0030424
GeneOntologyCellularComponentpresynaptic membrane

SCN10A SLC6A7 SCN1A SCN2A SCN8A

3.02e-05277285GO:0042734
GeneOntologyCellularComponentmembrane protein complex

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

9.63e-051498289GO:0098796
GeneOntologyCellularComponentintercalated disc

SCN1A SCN2A SCN5A

1.02e-0468283GO:0014704
GeneOntologyCellularComponentsynaptic membrane

SCN10A SLC6A7 CLSTN2 SCN1A SCN2A SCN8A

1.02e-04583286GO:0097060
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A SCN5A

1.59e-0479283GO:0030315
GeneOntologyCellularComponentmain axon

SCN1A SCN2A SCN8A

2.26e-0489283GO:0044304
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN2A SCN5A

2.66e-0494283GO:0044291
GeneOntologyCellularComponentpresynapse

SCN10A SLC6A7 WFS1 SCN1A SCN2A SCN8A

9.64e-04886286GO:0098793
GeneOntologyCellularComponentZ disc

SCN1A SCN5A SCN8A

1.06e-03151283GO:0030018
GeneOntologyCellularComponentI band

SCN1A SCN5A SCN8A

1.39e-03166283GO:0031674
GeneOntologyCellularComponentsarcolemma

SCN1A SCN2A SCN5A

2.05e-03190283GO:0042383
GeneOntologyCellularComponentglutamatergic synapse

SCN10A SLC6A7 CLSTN2 SCN2A SCN8A

4.19e-03817285GO:0098978
GeneOntologyCellularComponentsarcomere

SCN1A SCN5A SCN8A

4.39e-03249283GO:0030017
GeneOntologyCellularComponentmyofibril

SCN1A SCN5A SCN8A

5.67e-03273283GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

SCN1A SCN5A SCN8A

6.70e-03290283GO:0043292
HumanPhenoPhotosensitive tonic-clonic seizure

CILK1 SCN1A SCN2A SCN9A

3.43e-0815134HP:0007207
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

4.57e-0816134HP:0011172
HumanPhenoVisually-induced seizure

CILK1 SCN1A SCN2A SCN9A

7.65e-0818134HP:0020216
HumanPhenoReflex seizure

CILK1 SCN1A SCN2A SCN9A

1.82e-0722134HP:0020207
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

3.13e-0725134HP:0006813
HumanPhenoAbnormal autonomic nervous system physiology

SCN10A KCNE2 WFS1 SCN3A SCN5A SCN9A

3.65e-07130136HP:0012332
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

4.33e-0727134HP:0011171
HumanPhenoInfection-related seizure

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

6.99e-07145136HP:0032892
HumanPhenoSeizure precipitated by febrile infection

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

6.99e-07145136HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

6.99e-07145136HP:0002373
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

7.22e-078133HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

7.22e-078133HP:0200048
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A

1.05e-0681135HP:0020221
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

1.13e-0634134HP:0011169
HumanPhenoEEG with spike-wave complexes

CILK1 SCN1A SCN2A SCN8A SCN9A

1.58e-0688135HP:0010850
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

2.12e-0611133HP:0000466
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.71e-0642134HP:0002266
HumanPhenoBradycardia

SCN10A KCNE2 SCN4A SCN5A SCN9A

2.71e-0698135HP:0001662
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

2.82e-0612133HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

2.82e-0612133HP:0032898
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

3.66e-0613133HP:0007058
HumanPhenoStatus epilepticus

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

5.66e-06207136HP:0002133
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

5.81e-0615133HP:0011468
HumanPhenoBilateral tonic-clonic seizure with generalized onset

CILK1 SCN1A SCN2A SCN9A

6.45e-0652134HP:0025190
HumanPhenoCyanosis

SCN1A SCN2A SCN4A SCN8A SCN9A

6.52e-06117135HP:0000961
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

7.14e-0616133HP:0025101
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

8.65e-0617133HP:0032663
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

8.65e-0617133HP:0011151
HumanPhenoPes valgus

SCN1A SCN2A SCN4A SCN9A

8.70e-0656134HP:0008081
HumanPhenoFocal impaired awareness seizure

SCN1A SCN2A SCN3A SCN8A SCN9A

9.39e-06126135HP:0002384
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

1.04e-0518133HP:0032860
HumanPhenoSudden death

SCN10A KCNE2 SCN1A SCN5A SCN8A

1.14e-05131135HP:0001699
HumanPhenoAbnormal cardiac exercise stress test

SCN10A KCNE2 SCN5A

1.23e-0519133HP:0500018
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

1.44e-0520133HP:0032671
HumanPhenoGeneralized tonic seizure

SCN1A SCN2A SCN8A SCN9A

1.49e-0564134HP:0010818
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

1.68e-0521133HP:0004684
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A

1.68e-0566134HP:0010841
HumanPhenoDialeptic seizure

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

1.73e-05251136HP:0011146
HumanPhenoPoor fine motor coordination

PIEZO2 SCN1A SCN2A SCN9A

2.01e-0569134HP:0007010
HumanPhenoGeneralized myoclonic seizure

CILK1 SCN1A SCN2A SCN8A SCN9A

2.06e-05148135HP:0002123
HumanPhenoImpulsivity

SCN1A SCN2A SCN3A SCN8A SCN9A

2.13e-05149135HP:0100710
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A

2.23e-0523133HP:0100694
HumanPhenoEEG with generalized epileptiform discharges

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

2.63e-05270136HP:0011198
HumanPhenoTorsade de pointes

SCN10A KCNE2 SCN5A

2.89e-0525133HP:0001664
HumanPhenoHypokalemia

SCN10A KCNE2 SCN4A SCN5A

3.45e-0579134HP:0002900
HumanPhenoLimited knee extension

SCN1A SCN2A SCN9A

3.67e-0527133HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A SCN9A

3.67e-0527133HP:0031475
HumanPhenoFocal aware seizure

SCN1A SCN2A SCN9A

4.10e-0528133HP:0002349
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A SCN9A

4.57e-0529133HP:0032658
HumanPhenoProlonged QTc interval

SCN10A KCNE2 SCN5A

4.57e-0529133HP:0005184
HumanPhenoPoor motor coordination

PIEZO2 SCN1A SCN2A SCN9A

4.60e-0585134HP:0002275
HumanPhenoGeneralized non-motor (absence) seizure

CILK1 SCN1A SCN2A SCN8A SCN9A

4.78e-05176135HP:0002121
HumanPhenoProgressive gait ataxia

SCN1A SCN2A SCN9A

5.07e-0530133HP:0007240
HumanPhenoSinus bradycardia

SCN10A KCNE2 SCN5A

5.07e-0530133HP:0001688
HumanPhenoProgressive ataxia

SCN1A SCN2A SCN9A

5.07e-0530133HP:0001329
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.99e-055132HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.99e-055132HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.99e-055132HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.99e-055132HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.99e-055132HP:0032906
HumanPhenoAllodynia

SCN10A SCN9A

5.99e-055132HP:0012533
HumanPhenoCogwheel rigidity

SCN1A SCN2A SCN9A

6.17e-0532133HP:0002396
HumanPhenoObsessive-compulsive trait

SCN1A SCN2A SCN9A

6.78e-0533133HP:0008770
HumanPhenoInterictal epileptiform activity

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

6.78e-05319136HP:0011182
HumanPhenoAbnormal nervous system electrophysiology

CILK1 PIEZO2 NUP188 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A

7.28e-05924139HP:0001311
HumanPhenoCalcaneovalgus deformity

SCN1A SCN2A SCN9A

7.43e-0534133HP:0001848
HumanPhenoInterictal EEG abnormality

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

7.54e-05325136HP:0025373
HumanPhenoDeformed tarsal bones

SCN1A SCN2A SCN9A

8.11e-0535133HP:0008119
HumanPhenoLimitation of knee mobility

SCN1A SCN2A SCN9A

8.11e-0535133HP:0010501
HumanPhenoNon-motor seizure

CILK1 SCN1A SCN2A SCN8A SCN9A

8.21e-05197135HP:0033259
HumanPhenoLimitation of neck motion

SCN1A SCN2A SCN9A

8.83e-0536133HP:0005986
HumanPhenoAbnormal neck physiology

SCN1A SCN2A SCN9A

8.83e-0536133HP:0025669
HumanPhenoDisturbance of facial expression

SCN1A SCN2A SCN9A

8.83e-0536133HP:0005324
HumanPhenoNormal interictal EEG

SCN2A SCN8A

8.97e-056132HP:0002372
HumanPhenoAbnormal T-wave

SCN10A KCNE2 SCN5A

9.60e-0537133HP:0005135
HumanPhenoAbnormality of the autonomic nervous system

SCN10A KCNE2 WFS1 SCN3A SCN5A SCN9A

1.07e-04346136HP:0002270
HumanPhenoAbnormal tibia morphology

CILK1 SCN1A SCN2A SCN9A

1.14e-04107134HP:0002992
HumanPhenoFocal non-motor seizure

SCN1A SCN2A SCN8A

1.22e-0440133HP:0032679
HumanPhenoRigidity

SCN1A SCN2A SCN3A SCN8A SCN9A

1.22e-04214135HP:0002063
HumanPhenoAbnormality of central nervous system electrophysiology

CILK1 PIEZO2 NUP188 SCN1A SCN2A SCN3A SCN8A SCN9A

1.22e-04738138HP:0030178
HumanPhenoEyelid myoclonia seizure

SCN2A SCN8A

1.25e-047132HP:0032678
HumanPhenoAbnormal blood potassium concentration

SCN10A KCNE2 SCN4A SCN5A

1.41e-04113134HP:0011042
HumanPhenoEEG abnormality

CILK1 NUP188 SCN1A SCN2A SCN3A SCN8A SCN9A

1.54e-04548137HP:0002353
HumanPhenoMyoclonus

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

1.58e-04371136HP:0001336
HumanPhenoGeneralized-onset motor seizure

CILK1 SCN1A SCN2A SCN8A SCN9A

1.65e-04228135HP:0032677
HumanPhenoEEG with focal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A

1.66e-04118134HP:0011185
HumanPhenoPremature atrial contractions

KCNE2 SCN5A

1.67e-048132HP:0006699
HumanPhenoEpileptic encephalopathy

SCN1A SCN2A SCN3A SCN8A

1.72e-04119134HP:0200134
HumanPhenoReduced impulse control

CILK1 PIEZO2 WFS1 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A

1.80e-041032139HP:5200045
HumanPhenoAtypical absence seizure

SCN1A SCN2A SCN9A

1.85e-0446133HP:0007270
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN2A SCN9A

2.10e-0448133HP:0025100
HumanPhenoPermanent atrial fibrillation

KCNE2 SCN5A

2.14e-049132HP:0004754
HumanPhenoBilateral tonic-clonic seizure

CILK1 SCN1A SCN2A SCN3A SCN8A SCN9A

2.21e-04394136HP:0002069
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN2A SCN9A

2.24e-0449133HP:0007343
HumanPhenoFocal motor seizure

SCN1A SCN2A SCN8A SCN9A

2.49e-04131134HP:0011153
HumanPhenoBilateral tonic-clonic seizure with focal onset

SCN1A SCN2A SCN8A

2.67e-0452133HP:0007334
HumanPhenoApneic episodes in infancy

SCN4A SCN5A

2.67e-0410132HP:0005949
HumanPhenoSudden unexpected death in epilepsy

SCN1A SCN8A

2.67e-0410132HP:0033258
HumanPhenoErythromelalgia

SCN10A SCN9A

2.67e-0410132HP:0032147
HumanPhenoProlonged QT interval

SCN10A KCNE2 SCN5A

2.99e-0454133HP:0001657
MousePhenoabnormal action potential

SCN10A SCN1A SCN2A SCN5A SCN8A SCN9A

3.20e-08133216MP:0005402
MousePhenoabnormal nervous system electrophysiology

SCN10A SCN1A SCN2A SCN5A SCN8A SCN9A

6.54e-06329216MP:0002272
MousePhenoventricular fibrillation

SCN1A SCN5A

4.49e-057212MP:0006110
MousePhenoabnormal stationary movement

SCN10A WFS1 SCN1A SCN8A

6.11e-05147214MP:0001388
MousePhenoabnormal breathing pattern

SCN10A SCN1A SCN2A SCN4A SCN8A

7.08e-05303215MP:0001951
MousePhenoincreased locomotor activity

CLSTN2 WFS1 SCN1A SCN2A

1.28e-04178214MP:0031391
MousePhenoimpaired ability to fire action potentials

SCN10A SCN1A

1.66e-0413212MP:0002578
MousePhenoabnormal respiration

SCN10A CILK1 SCN1A SCN2A SCN4A SCN8A

1.87e-04598216MP:0001943
MousePhenofibrillation

SCN1A SCN5A

1.93e-0414212MP:0006109
MousePhenosinus bradycardia

SCN10A SCN5A

1.93e-0414212MP:0010637
MousePhenoabnormal respiratory function

SCN10A SCN1A SCN2A SCN4A SCN8A

2.58e-04399215MP:0002327
MousePhenoakinesia

SCN1A SCN4A

4.44e-0421212MP:0002690
MousePhenoabnormal head movements

WFS1 SCN1A SCN8A

4.69e-04103213MP:0000436
MousePhenoincreased vertical activity

CLSTN2 PIEZO2 WFS1 CSNK2A2

4.70e-04250214MP:0002574
MousePhenoabnormal spatial reference memory

SLC6A7 CLSTN2 SCN1A

5.25e-04107213MP:0008414
MousePhenoabnormal spike wave discharge

SCN1A SCN8A

5.82e-0424212MP:0008840
MousePhenoventricular premature beat

SCN1A SCN5A

6.32e-0425212MP:0009732
MousePhenoapnea

SCN10A SCN1A

7.38e-0427212MP:0001957
MousePhenoimpaired muscle relaxation

SCN4A SCN8A

7.94e-0428212MP:0003157
MousePhenoabnormal seizure response to electrical stimulation

SCN1A SCN9A

1.04e-0332212MP:0001650
MousePhenohyperactivity

CLSTN2 PIEZO2 ZDHHC23 WFS1 CSNK2A2 SCN1A SCN2A

1.16e-031172217MP:0001399
MousePhenoabnormal single cell response

SCN10A SCN9A

1.24e-0335212MP:0003463
MousePhenoabsence seizures

SCN1A SCN8A

1.24e-0335212MP:0003216
MousePhenoabnormal mechanical nociception

SCN10A SCN9A

1.31e-0336212MP:0002734
MousePhenoabnormal respiratory system physiology

SCN10A CILK1 SCN1A SCN2A SCN4A SCN8A

1.62e-03897216MP:0002133
MousePhenononconvulsive seizures

SCN1A SCN8A

1.62e-0340212MP:0000948
MousePhenoabnormal spermatogonia morphology

WFS1 CSNK2A2

1.78e-0342212MP:0006378
MousePhenoseizures

SCN1A SCN5A SCN8A SCN9A

1.83e-03360214MP:0002064
MousePhenoabnormal social investigation

WFS1 SCN1A SCN2A

2.03e-03171213MP:0001360
DomainNa_channel_asu

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.72e-2210278IPR001696
DomainNa_trans_assoc

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.72e-2210278IPR010526
DomainNa_trans_assoc

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.72e-2210278PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

5.03e-186276PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

5.03e-186276IPR024583
DomainChannel_four-helix_dom

SCN10A SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.32e-1757279IPR027359
Domain-

SCN10A SLC9C2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.32e-17572791.20.120.350
DomainIQ_motif_EF-hand-BS

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.36e-1390278IPR000048
DomainIQ

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.71e-1393278PS50096
DomainIon_trans_dom

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.03e-12114278IPR005821
DomainIon_trans

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.03e-12114278PF00520
DomainIQ

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.83e-1181277SM00015
DomainIQ

SCN10A SCN1A SCN3A SCN4A SCN8A SCN9A

6.76e-1071276PF00612
DomainREJ_dom

PKD1L2 PKDREJ

1.21e-054272IPR014010
DomainREJ

PKD1L2 PKDREJ

1.21e-054272PS51111
DomainPKD_2

PKD1L2 PKDREJ

2.01e-055272IPR003915
DomainREJ

PKD1L2 PKDREJ

3.01e-056272PF02010
DomainPKD/REJ-like

PKD1L2 PKDREJ

3.01e-056272IPR002859
DomainPKD1_2_channel

PKD1L2 PKDREJ

1.10e-0411272IPR013122
DomainPKD_channel

PKD1L2 PKDREJ

1.10e-0411272PF08016
DomainABC_A

ABCA6 ABCA8

1.32e-0412272IPR026082
DomainLH2

PKD1L2 PKDREJ

3.04e-0418272SM00308
DomainPLAT

PKD1L2 PKDREJ

4.16e-0421272PS50095
DomainPLAT/LH2_dom

PKD1L2 PKDREJ

4.16e-0421272IPR001024
Domain-

PKD1L2 PKDREJ

4.16e-04212722.60.60.20
DomainPLAT

PKD1L2 PKDREJ

4.16e-0421272PF01477
DomainEF-hand-dom_pair

SCN1A SCN3A SCN8A SCN9A

7.25e-04287274IPR011992
DomainGPS

PKD1L2 PKDREJ

1.10e-0334272SM00303
DomainGPS

PKD1L2 PKDREJ

1.30e-0337272IPR000203
DomainABC_TRANSPORTER_2

ABCA6 ABCA8

2.18e-0348272PS50893
DomainABC_tran

ABCA6 ABCA8

2.18e-0348272PF00005
DomainABC_TRANSPORTER_1

ABCA6 ABCA8

2.27e-0349272PS00211
DomainABC_transporter-like

ABCA6 ABCA8

2.36e-0350272IPR003439
DomainAAA+_ATPase

ABCA6 ABCA8

1.83e-02144272IPR003593
DomainAAA

ABCA6 ABCA8

1.83e-02144272SM00382
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.53e-1731208M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.37e-1732208M27455
PathwayREACTOME_L1CAM_INTERACTIONS

SCN10A CSNK2A2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.90e-14121209M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.62e-14130209M27454
PathwayREACTOME_MUSCLE_CONTRACTION

SCN10A KCNE2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.27e-12203209M5485
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.87e-08367208M48346
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN10A CSNK2A2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

3.30e-08575209M29853
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

5.90e-0828204M45519
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

SCN10A SCN8A SCN9A

3.57e-0546203M46450
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

SCN2A SCN3A SCN9A

3.81e-0547203M42524
PathwayWP_RETT_SYNDROME

SCN1A SCN2A SCN8A

4.06e-0548203M39759
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

SCN10A CSNK2A2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.66e-051432209M509
PathwayREACTOME_SENSORY_PERCEPTION

OR2T29 OR2T5 SCN2A SCN3A SCN9A

1.62e-03636205M41834
PathwayKEGG_ABC_TRANSPORTERS

ABCA6 ABCA8

1.75e-0344202M11911
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.27e-25928816382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN10A SCN1A SCN2A SCN3A SCN8A SCN9A

1.53e-19628623652591
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN10A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

1.66e-191328715123669
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A

1.29e-17928615746173
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN4A SCN5A SCN8A

2.32e-16528517724025
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN10A KCNE2 SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A

1.54e-1313928816985003
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN5A SCN8A

1.83e-131228530175250
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

3.36e-13428417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

3.36e-13428435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

3.36e-13428429578003
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

1.68e-1252848812438
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN5A SCN8A SCN9A

1.68e-12528422875929
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

4.67e-10328319284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

4.67e-10328312610651
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

4.67e-10328333895391
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

4.67e-10328317928448
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

4.67e-10328323859570
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN10A SCN3A SCN9A

4.67e-10328319699781
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

4.67e-10328314973256
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

4.67e-10328318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

4.67e-10328317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

4.67e-10328332845893
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

4.67e-10328320038812
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

4.67e-10328328518218
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

1.87e-09428321156207
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

1.87e-09428335801810
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN10A SCN1A SCN9A

1.87e-09428322260870
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

1.87e-0942838974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

4.67e-0952831679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

4.67e-09528324337656
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN10A SCN8A SCN9A

9.33e-09628316029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN10A SCN3A SCN8A

9.33e-09628323711479
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

1.63e-08728315272007
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN10A SCN3A SCN9A

1.63e-08728324440715
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

1.63e-08728325818041
Pubmed

A role for Piezo2 in EPAC1-dependent mechanical allodynia.

SCN10A PIEZO2 SCN9A

1.63e-08728323575686
Pubmed

Significant determinants of mouse pain behaviour.

SCN10A SCN3A SCN9A

2.61e-08828325101983
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN4A SCN5A

2.61e-0882839412493
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN10A SCN3A SCN9A

3.91e-0892838854872
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

3.91e-08928317884088
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

1.02e-07122838169823
Pubmed

A high-density association screen of 155 ion transport genes for involvement with common migraine.

KCNE2 SCN5A SCN9A

1.02e-071228318676988
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

2.11e-07152839726281
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN10A SCN5A

6.25e-07228224642470
Pubmed

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

SCN1A SCN5A

6.25e-07228216054936
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

6.25e-07228229649454
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

6.25e-07228217805013
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

6.25e-07228220346423
Pubmed

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.

SCN1A SCN5A

6.25e-07228233712547
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

6.25e-07228226311622
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

6.25e-07228237901435
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

6.25e-07228233411788
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

6.25e-07228218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

6.25e-07228226410685
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

6.25e-07228231943325
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

6.25e-07228211834499
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

6.25e-07228210827969
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

6.25e-07228215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

6.25e-07228227690330
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

6.25e-07228219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

6.25e-07228235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

6.25e-07228211245985
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

6.25e-07228226861708
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN10A SCN5A

6.25e-07228215047701
Pubmed

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

SCN10A SCN9A

6.25e-07228216111501
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

6.25e-07228215760941
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

6.25e-07228227174182
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

6.25e-07228221377452
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

6.25e-0722821317301
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

6.25e-07228218601978
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN10A SCN5A

6.25e-07228224998131
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

6.25e-07228223965409
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

6.25e-07228223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

6.25e-07228227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

6.25e-07228233096315
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

6.25e-07228219465131
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

6.25e-07228224990319
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

6.25e-07228230944319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

6.25e-07228225172946
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

6.25e-07228216847056
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

6.25e-07228231439038
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN10A SCN5A

6.25e-07228224360055
Pubmed

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

SCN10A SCN5A

6.25e-07228231292628
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

6.25e-07228237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

6.25e-07228217881658
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

6.25e-07228230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

6.25e-07228223735284
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN10A SCN5A

6.25e-07228232330377
Pubmed

Brugada Syndrome

SCN10A KCNE2 SCN5A

9.35e-072428320301690
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

1.87e-06328224704313
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

1.87e-06328219270815
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

1.87e-06328228784306
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

1.87e-06328216052353
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

1.87e-06328232185219
Pubmed

Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.

SCN10A SCN9A

1.87e-06328238999942
Pubmed

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.

SCN10A SCN9A

1.87e-06328215314237
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

1.87e-06328232005694
Pubmed

The cell and molecular basis of mechanical, cold, and inflammatory pain.

SCN10A SCN9A

1.87e-06328218669863
Pubmed

Calmodulin mediates Ca2+ sensitivity of sodium channels.

SCN2A SCN5A

1.87e-06328215316014
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

1.87e-06328225155934
InteractionSCN11A interactions

SCN10A SCN1A SCN5A SCN8A SCN9A

5.71e-1215255int:SCN11A
InteractionSCN5A interactions

SCN10A SCN1A SCN5A SCN8A SCN9A

2.84e-0947255int:SCN5A
InteractionCACNA1D interactions

SCN10A SCN1A SCN5A SCN9A

1.92e-0824254int:CACNA1D
InteractionSCN1A interactions

SCN10A SCN1A SCN5A SCN9A

4.28e-0829254int:SCN1A
InteractionNEDD4L interactions

SCN10A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

8.96e-08320257int:NEDD4L
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

9.40e-088253int:SCN4B
InteractionSCN10A interactions

SCN10A SCN1A SCN5A

2.76e-0711253int:SCN10A
InteractionNALCN interactions

SCN1A SCN5A SCN9A

6.08e-0714253int:NALCN
InteractionCACNA1C interactions

KCNE2 SCN1A SCN5A SCN9A

9.16e-0761254int:CACNA1C
InteractionSCN8A interactions

SCN4A SCN5A SCN8A

1.90e-0620253int:SCN8A
InteractionSCN9A interactions

SCN1A SCN5A SCN9A

2.21e-0621253int:SCN9A
InteractionNEDD4 interactions

SCN10A SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

3.16e-06544257int:NEDD4
InteractionCACNA1B interactions

SCN1A SCN5A SCN9A

1.27e-0537253int:CACNA1B
InteractionCACNA1A interactions

SCN10A SCN1A SCN5A SCN9A

1.51e-05123254int:CACNA1A
InteractionABCA8 interactions

ABCA6 ABCA8

5.29e-059252int:ABCA8
InteractionABCA6 interactions

ABCA6 ABCA8

6.61e-0510252int:ABCA6
InteractionCALM1 interactions

WFS1 CSNK2A2 SCN1A SCN2A SCN4A SCN5A

9.38e-05626256int:CALM1
InteractionSCN4A interactions

SPPL2B SCN4A SCN8A

2.37e-0498253int:SCN4A
InteractionSNTA1 interactions

SCN1A SCN4A SCN5A

2.91e-04105253int:SNTA1
InteractionPIGW interactions

SPPL2B SCN4A

4.71e-0426252int:PIGW
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN9A

1.09e-06127284chr2q24
Cytoband2q24

SCN3A SCN9A

1.97e-05112822q24
Cytoband2q24.3

SCN1A SCN2A

4.28e-05162822q24.3
CytobandEnsembl 112 genes in cytogenetic band chr17q24

ABCA6 ABCA8

1.64e-0398282chr17q24
Cytoband1q44

OR2T29 OR2T5

2.06e-031102821q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T29 OR2T5

2.78e-03128282chr1q44
CytobandEnsembl 112 genes in cytogenetic band chr3p22

SCN10A SCN5A

5.64e-03184282chr3p22
CytobandEnsembl 112 genes in cytogenetic band chr3q13

TMEM39A ZDHHC23

8.03e-03221282chr3q13
GeneFamilySodium voltage-gated channel alpha subunits

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.40e-2491981203
GeneFamilyATP binding cassette subfamily A

ABCA6 ABCA8

9.45e-0514192805
GeneFamilyOlfactory receptors, family 2

OR2T29 OR2T5

6.18e-03113192149
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PKDREJ SCN1A SCN2A SCN3A

2.60e-0615528477fdae85d36efb776db977eb424b32487ef222e4
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC6A7 PIEZO2 ABCA6 ABCA8

2.74e-06157284f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC6A7 PIEZO2 ABCA6 ABCA8

2.81e-06158284e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

4.50e-06178284ad3de3e03a401dac64431a541899445262246347
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

PIEZO2 WFS1 SCN3A SCN9A

4.60e-06179284411620201a860716a8773b92f50f7b94ef34a586
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

4.81e-06181284e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

4.92e-0618228453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

5.02e-061832844d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PKD1L2 SCN2A SCN9A

5.13e-06184284ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PKD1L2 SCN2A SCN9A

5.13e-061842842cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PKD1L2 SCN2A SCN9A

5.13e-061842842b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

5.36e-0618628440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 SCN1A SCN2A SCN8A

5.36e-061862847278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

5.36e-0618628420340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CLSTN2 SCN2A SCN3A SCN9A

5.59e-06188284b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

PIEZO2 WFS1 SCN3A SCN9A

5.71e-06189284c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

PIEZO2 SCN3A SCN8A SCN9A

5.71e-061892846baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

5.83e-061902841f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

5.83e-061902842306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

5.95e-06191284a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

6.07e-061922849093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 WFS1 SCN3A SCN9A

6.07e-061922845f4f44f15d3a2846981e68296643a4634930a211
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLSTN2 PIEZO2 ABCA6 ABCA8

6.07e-06192284c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

6.07e-061922849ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIEZO2 WFS1 SCN3A SCN9A

6.07e-06192284cbe57cda44232b183821ac633b60a2668265e616
ToppCellNeuroendocrine|World / Class top

PIEZO2 SCN3A SCN8A SCN9A

6.07e-061922840199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 WFS1 SCN3A SCN9A

6.07e-061922845e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLSTN2 PIEZO2 ABCA6 ABCA8

6.07e-06192284e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 SCN1A SCN2A SCN8A

6.20e-06193284be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLSTN2 PIEZO2 ABCA6 ABCA8

6.20e-061932849ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

6.20e-06193284040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 SCN1A SCN2A SCN8A

6.20e-061932840c652ebe22ce5d2927599dd97ef1920547858395
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 WFS1 SCN3A SCN9A

6.20e-06193284e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 SCN1A SCN2A SCN8A

6.20e-061932848689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 CLSTN2 SCN2A SCN3A

6.20e-06193284461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 CLSTN2 SCN2A SCN3A

6.20e-061932840dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

PIEZO2 WFS1 SCN3A SCN9A

6.33e-061942849441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.46e-061952848e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 WFS1 SCN3A SCN9A

6.46e-06195284fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 WFS1 SCN3A SCN9A

6.46e-0619528483d45ff5e5bc704448431149fffb2e4c1278f279
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLSTN2 PIEZO2 ABCA6 ABCA8

6.46e-06195284f54bc4454270ff06e85596f98199372b50d0179f
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.46e-06195284f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.59e-061962843e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

PIEZO2 WFS1 SCN3A SCN9A

6.59e-0619628436f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

6.72e-06197284b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 PIEZO2 ABCA6 ABCA8

6.72e-06197284c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A SCN3A SCN8A

6.86e-061982846d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellmedial-Endothelial-Lymphatic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.86e-0619828441983d405215b974044e2e9e6c212b134336a6fe
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A SCN3A SCN8A

6.86e-06198284c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellmedial-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.86e-06198284e4274584512a72270087a1ab104fab449a2f83bc
ToppCellmedial-Endothelial-Lymphatic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 WFS1 SCN3A SCN9A

6.86e-061982841760fede363544bc0fa2e22fe36aff522abd2525
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A SCN3A SCN8A

6.86e-061982844ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

CLSTN2 PIEZO2 ABCA6 ABCA8

7.00e-0619928412133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 WFS1 SCN3A SCN9A

7.00e-061992841587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 WFS1 SCN3A SCN9A

7.00e-06199284a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-06200284310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-06200284c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CLSTN2 PIEZO2 ABCA6 ABCA8

7.14e-0620028474e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-062002844fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-06200284f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-06200284cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A

7.14e-06200284961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

CLSTN2 ABCA6 ABCA8

9.12e-05140283b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCN10A TMCO5B ABCA6

9.32e-051412835ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A7 ABCA6 ABCA8

1.01e-04145283051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN10A SCN1A SCN9A

1.01e-0414528396712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A7 CLSTN2 SCN3A

1.12e-0415028347ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 ABCA6 ABCA8

1.12e-041502831270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLSTN2 ABCA6 ABCA8

1.12e-04150283156118ce1d69522624196410cba18b8354cd0bb4
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN10A PKDREJ SCN9A

1.31e-04158283f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN10A PKDREJ SCN9A

1.31e-041582838c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

KCNE2 PIEZO2 ABCA6

1.33e-041592833f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-041612839466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-04161283133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.38e-04161283cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A7 ZDHHC23 SCN2A

1.38e-04161283ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6|TCGA-Colorectal / Sample_Type by Project: Shred V9

KCNE2 ABCA8 SCN9A

1.41e-041622837f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.41e-0416228396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 ABCA6 ABCA8

1.43e-041632838e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 ABCA6 ABCA8

1.43e-04163283bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA8 SCN5A SCN9A

1.46e-0416428357301178e420983c0cb72178e288a3a0449fdda3
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

KCNE2 PIEZO2 ABCA6

1.46e-041642832ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.48e-04165283347b59aa625a8a960828b8620824d8ac48990e07
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

KCNE2 SCN3A SCN9A

1.48e-041652837b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.48e-041652831890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ABCA6 ABCA8 SCN9A

1.48e-041652836ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.48e-04165283507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A SCN3A SCN5A

1.48e-0416528339a25be081a5d59c7cf107a997d352793d5025fb
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-pDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ABCA6 SLC9C2 SCN9A

1.51e-041662839fa90d9d484563d44738bb2c6eb0775dffc4d549
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PIEZO2 ABCA6 SCN8A

1.51e-0416628365dafed953b01a9830b54309af75c7a561e88336
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA6 ABCA8 SCN9A

1.56e-0416828388c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

KCNE2 PIEZO2 SCN3A

1.59e-041692838889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA8 SCN5A SCN9A

1.59e-041692832456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PKDREJ SCN2A SCN3A

1.59e-041692830332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

ABCA6 ABCA8 SCN9A

1.59e-04169283a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellICU-SEP-Myeloid-pDC|ICU-SEP / Disease, Lineage and Cell Type

ABCA6 SLC9C2 SCN9A

1.65e-0417128372c448a0dc4c569bd6b465f9aa395f38034e7ea6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A7 CLSTN2 ZDHHC23

1.65e-04171283f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A7 CLSTN2 ZDHHC23

1.65e-041712836a489a75eeab2a2d48d604682e93599c20a945fe
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC6A7 CLSTN2 SCN3A

1.65e-041712839d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

KCNE2 ABCA8 SCN9A

1.68e-0417228394842346c84542a5243bd765e49f4af8bc5182db
DrugAPETx1, Anthopleura elegantissima

SCN10A SCN2A SCN3A SCN4A SCN8A

1.16e-146285ctd:C475726
DrugZonisamide

SCN1A SCN2A SCN3A SCN4A SCN5A SCN9A

2.39e-1417286DB00909
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN10A SCN2A SCN3A SCN8A

1.28e-108284ctd:C489827
DrugAC1L1MOZ

SCN10A SCN3A SCN4A SCN5A SCN9A

1.53e-1027285CID000031958
Drugmexiletine

SCN10A KCNE2 SCN3A SCN4A SCN5A SCN9A

1.68e-1066286CID000004178
Drugdibucaine

SCN10A ZDHHC23 SCN3A SCN4A SCN5A SCN9A

2.03e-1068286CID000003025
Drugflecainide

SCN10A KCNE2 SCN3A SCN4A SCN5A SCN9A

2.64e-1071286CID000003355
Drugtocainide

SCN10A SCN3A SCN4A SCN5A SCN9A

2.69e-1030285CID000038945
DrugSodium

SCN10A SCN2A SCN3A SCN5A SCN8A SCN9A

7.42e-1084286ctd:D012964
Drugbenzocaine

SCN10A SCN2A SCN3A SCN4A SCN9A

8.18e-1037285CID000002337
DrugTetrodotoxin

SCN2A SCN3A SCN5A SCN8A SCN9A

1.23e-0940285ctd:D013779
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A SCN9A

1.67e-093283ctd:C561228
Drugpilsicainide

SCN10A SCN3A SCN4A SCN5A SCN9A

2.55e-0946285CID000004820
Drugverapamil

SCN10A KCNE2 CILK1 ABCA6 ABCA8 SCN3A SCN4A SCN5A SCN9A

4.42e-09490289CID000002520
Druglamotrigine

SCN10A SCN2A SCN3A SCN4A SCN5A SCN9A

5.28e-09116286CID000003878
DrugScorpion Venoms

SCN2A SCN3A SCN4A SCN9A

5.53e-0918284ctd:D012604
DrugAPETx2 protein, Anthopleura elegantissima

SCN10A SCN2A SCN8A

6.66e-094283ctd:C501880
DrugLidocaine

SCN10A SCN5A SCN9A

6.66e-094283DB00281
Drugdiprafenone

SCN10A SCN3A SCN4A SCN9A

7.00e-0919284CID000071249
Drugtriamterene

SCN10A ZDHHC23 SCN3A SCN4A SCN9A

8.45e-0958285CID000005546
Drugsaxitoxin

SCN10A SCN2A SCN3A SCN4A SCN9A

1.51e-0865285CID000037165
DrugAC1L1CQC

SCN10A SCN3A SCN4A SCN5A SCN9A

1.51e-0865285CID000002012
Drugdisopyramide

SCN10A SCN3A SCN4A SCN5A SCN9A

1.64e-0866285CID000003114
DrugAC1NT1AF

SCN10A SCN3A SCN4A SCN9A

2.27e-0825284CID005322157
DrugPirmenolum

SCN10A SCN3A SCN4A SCN9A

2.68e-0826284CID000004853
Drug1, 3-diallylurea

SCN10A CILK1 SCN3A SCN4A SCN9A

2.93e-0874285CID000074537
Drugnefopam

SCN10A SCN3A SCN4A SCN9A

3.15e-0827284CID000004450
DrugPbTx-1

SCN10A SCN3A SCN4A SCN9A

3.15e-0827284CID006437089
Drugfenpropathrin

SCN10A SCN2A SCN3A

3.32e-086283ctd:C044267
Druglidocaine

SCN10A CILK1 SCN3A SCN4A SCN5A SCN9A

3.63e-08160286CID000003676
Drugparaben

SCN10A SCN3A SCN4A SCN9A

3.67e-0828284CID000007175
DrugNSC93767

SCN10A SCN3A SCN4A SCN9A

6.42e-0832284CID000005658
Drugcarbamazepine

SCN10A SCN2A SCN3A SCN4A SCN5A SCN9A

7.09e-08179286CID000002554
DrugNSC7524

SCN10A SCN2A SCN3A SCN4A SCN5A SCN9A

7.82e-08182286CID000005657
Drug5-hydroxypropafenone

SCN10A SCN3A SCN4A SCN9A

8.27e-0834284CID000107927
Drugpropafenone

SCN10A SCN3A SCN4A SCN5A SCN9A

1.21e-0798285CID000004932
Drugaprindine

SCN10A SCN3A SCN4A SCN9A

1.31e-0738284CID000002218
DrugMexiletine

SCN10A SCN5A SCN9A

1.39e-079283ctd:D008801
DrugAC1NPPZW

CILK1 SCN2A SCN4A SCN5A SCN9A

1.55e-07103285CID005183170
DrugS-ropivacaine

SCN10A SCN3A SCN4A SCN9A

1.62e-0740284CID000071273
Drugpyraclofos

KCNE2 SCN2A SCN4A SCN5A SCN9A

1.79e-07106285CID000093460
Drugquindine

SCN10A KCNE2 SCN3A SCN4A SCN5A SCN9A

2.33e-07219286CID000001065
Drugphenytoin

SCN10A SCN2A SCN3A SCN4A SCN5A SCN9A

2.33e-07219286CID000001775
Drugspiradoline

SCN10A SCN3A SCN4A SCN9A

2.88e-0746284CID000005620
Drugindoxacarb

SCN10A SCN3A SCN4A SCN9A

3.73e-0749284CID000107720
Drugbepridil

SCN10A SCN3A SCN4A SCN5A SCN9A

4.25e-07126285CID000002351
DrugAC1NSN3X

SCN10A SCN3A SCN4A SCN9A

5.55e-0754284CID005366189
Drugtetradotoxin

SCN10A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

6.65e-07428287CID000020382
Drugdecamethrin

SCN10A SCN1A SCN2A SCN3A SCN8A

8.83e-07146285ctd:C017180
Drugzonisamide

SCN10A SCN3A SCN4A SCN9A

9.72e-0762284CID000005734
Drugdofetilide

KCNE2 SCN4A SCN5A SCN9A

1.04e-0663284CID000071329
Drugresiniferatoxin

SCN10A SCN3A SCN4A SCN9A

1.25e-0666284CID000104826
Drugmoricizine

SCN4A SCN5A SCN9A

1.34e-0618283CID000034632
Drugamiodarone

SCN10A SCN3A SCN4A SCN5A SCN9A

1.39e-06160285CID000002156
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.46e-062282ctd:C502265
DrugHexylcaine

SCN10A SCN5A

1.46e-062282DB00473
DrugRanolazine

SCN5A SCN9A

1.46e-062282DB00243
DrugPhenytoin

SCN1A SCN5A

1.46e-062282DB00252
DrugFlecainide

SCN4A SCN5A

1.46e-062282DB01195
DrugGBR 12909

SCN10A SCN3A SCN4A SCN9A

1.50e-0669284CID000003455
DrugT2755

SCN10A SCN3A SCN4A SCN9A

1.68e-0671284CID000005514
Druggabapentin

SCN10A SCN3A SCN4A SCN5A SCN9A

1.82e-06169285CID000003446
Drugsotalol

KCNE2 SCN4A SCN5A SCN9A

1.88e-0673284CID000005253
Drugimide

SCN10A SCN3A SCN4A SCN9A

1.98e-0674284CID000443040
Drugisofagomine

SCN10A SCN4A SCN5A SCN9A

2.09e-0675284CID000447607
Drugdiphenhydramine

SCN10A SCN3A SCN4A SCN9A

2.09e-0675284CID000003100
Drugriluzole

SCN10A SCN3A SCN4A SCN5A SCN9A

2.10e-06174285CID000005070
Drugtoluene

SCN10A CLSTN2 SCN3A SCN4A SCN9A

2.16e-06175285CID000001140
Drugbupropion

SCN10A SCN3A SCN4A SCN9A

2.85e-0681284CID000000444
DrugQX-314

CILK1 SCN4A SCN5A SCN9A

3.00e-0682284CID000003925
Drugprocainamide

SCN10A SCN3A SCN4A SCN5A SCN9A

3.23e-06190285CID000004913
DrugMulticide

SCN2A SCN4A SCN9A

3.76e-0625283CID000024365
DrugDibucaine

SCN10A SCN5A

4.37e-063282DB00527
DrugDPI 201-106

SCN4A SCN5A SCN9A

5.35e-0628283CID000005190
Drugencainide

SCN4A SCN5A SCN9A

5.35e-0628283CID000048040
Drugcyfluthrin

SCN10A SCN2A SCN3A

5.96e-0629283ctd:C052570
Drugtrimethoprim

SCN10A SCN3A SCN4A SCN9A

6.36e-0699284CID000005578
Drugoxcarbazepine

SCN4A SCN5A SCN9A

6.61e-0630283CID000034312
Drugisradipine

SCN10A SCN3A SCN4A SCN9A

6.61e-06100284CID000003784
DrugFospropofol

SCN2A SCN4A

8.74e-064282DB06716
DrugPropofol

SCN2A SCN4A

8.74e-064282DB00818
DrugNSC15627

SCN4A SCN5A SCN9A

9.72e-0634283CID000002073
Drugsodium

SCN10A SLC6A7 KCNE2 SCN2A SCN3A SCN4A SCN5A SCN9A

1.26e-05944288CID000000923
Drugsipatrigine

SCN2A SCN4A SCN9A

1.26e-0537283CID000060803
Drugisoproterenol

SCN10A SLC6A7 KCNE2 SCN3A SCN4A SCN5A SCN9A

1.27e-05669287CID000003779
Drughydrochlorothiazide

SCN10A SCN3A SCN4A SCN9A

1.36e-05120284CID000003639
Drugranolazine

SCN4A SCN5A SCN9A

1.48e-0539283CID000056959
Drugbupivacaine

SCN10A SCN3A SCN4A SCN9A

1.60e-05125284CID000002474
Drugtriphosphoinositide

SCN10A KCNE2 SCN3A SCN4A SCN9A

1.87e-05273285CID009543520
Drugpotassium

SCN10A SLC6A7 KCNE2 SCN2A SCN3A SCN4A SCN5A SCN9A

2.02e-051008288CID000000813
Drugclenbuterol

SCN10A SCN3A SCN4A SCN9A

2.64e-05142284CID000002783
Drugsalbutamol

SCN10A SCN3A SCN4A SCN9A

2.95e-05146284CID000002083
Drugfluorocyclobutane

SCN2A SCN4A

3.05e-057282CID011051569
Drugprocaine

SCN10A SCN3A SCN4A SCN9A

3.54e-05153284CID000004914
Drugantipyrine

CILK1 CLSTN2 SCN4A

3.74e-0553283CID000002206
Drug5,5'-dimethyl-2,2'-bipyridine

CLSTN2 SCN5A

4.07e-058282CID000015664
DrugCocaine

SCN10A SCN5A

4.07e-058282DB00907
Drugdihydrochloride

SCN10A SCN3A SCN4A SCN9A

4.11e-05159284CID000070978
Drugcyclaine

SCN10A SCN5A

5.22e-059282CID000010770
Drugmethylglucamine

SCN4A SCN8A SCN9A

6.00e-0562283CID000004049
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.93e-2410268DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

4.93e-2410268DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

5.42e-2312268DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN10A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

1.05e-12163268DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

3.43e-0922264DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

5.08e-089263C3502809
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

1.73e-0713263C0751122
DiseaseRomano-Ward Syndrome

SCN10A KCNE2 SCN5A

3.38e-0716263C0035828
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

7.47e-072262C4551549
DiseaseB Virus Infection

SCN8A SCN9A

2.24e-063262C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

2.24e-063262cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

2.24e-063262C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

2.24e-063262C0019372
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN10A SCN9A

2.24e-063262C1833661
DiseasePrimary Erythermalgia

SCN10A SCN9A

2.24e-063262C0014805
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A

2.47e-06109264C0014544
DiseaseBrugada ECG Pattern

SCN10A SCN5A

4.47e-064262C1721096
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

1.12e-056262C0220669
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN10A SCN9A

1.56e-057262C0020075
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.56e-057262C0149886
Diseaselong QT syndrome (is_implicated_in)

KCNE2 SCN5A

1.56e-057262DOID:2843 (is_implicated_in)
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.56e-057262C0751057
Diseaseelectrocardiography, PR interval

SCN10A SCN5A

1.56e-057262EFO_0004327, EFO_0004462
DiseaseCongenital Pain Insensitivity

SCN10A SCN9A

1.56e-057262C0002768
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

2.08e-058262C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

2.08e-058262C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

2.08e-058262C0338479
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

2.08e-058262C0438414
DiseaseVentricular Fibrillation

SCN10A KCNE2

2.08e-058262C0042510
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

2.08e-058262C0751120
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

2.08e-058262C0393703
DiseaseFebrile Convulsions

SCN1A SCN2A

2.68e-059262C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

2.68e-059262C0014550
Diseasesupraventricular ectopy

SCN10A SCN5A

2.68e-059262EFO_0009277
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

3.35e-0510262C0917800
DiseaseCongenital long QT syndrome

KCNE2 SCN5A

4.09e-0511262cv:C1141890
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

4.09e-0511262C0393702
DiseaseLong QT Syndrome

KCNE2 SCN5A

4.09e-0511262C0023976
DiseaseLong QT syndrome

KCNE2 SCN5A

4.90e-0512262cv:C0023976
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A

5.14e-0582263C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A

5.14e-0582263C0751111
DiseaseAura

SCN1A SCN2A SCN8A

5.14e-0582263C0236018
DiseaseBrugada Syndrome 1

SCN10A SCN5A

5.79e-0513262C4551804
DiseaseT wave morphology measurement

SCN10A SCN5A

6.75e-0514262EFO_0008398
Diseasefamilial atrial fibrillation (is_implicated_in)

KCNE2 SCN5A

6.75e-0514262DOID:0050650 (is_implicated_in)
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A

7.48e-0593263C1535926
DiseaseMMR-related febrile seizures

SCN1A SCN2A

7.78e-0515262EFO_0006519
DiseaseP wave duration

SCN10A SCN5A

7.78e-0515262EFO_0005094
DiseaseNeuralgia, Supraorbital

SCN10A SCN9A

8.89e-0516262C0038870
DiseaseNeuralgia, Iliohypogastric Nerve

SCN10A SCN9A

8.89e-0516262C0423712
DiseaseNeuralgia, Perineal

SCN10A SCN9A

8.89e-0516262C0423711
DiseaseNeuralgia

SCN10A SCN9A

8.89e-0516262C0027796
DiseaseNeuralgia, Atypical

SCN10A SCN9A

8.89e-0516262C0234247
DiseaseNeuralgia, Stump

SCN10A SCN9A

8.89e-0516262C0234249
DiseaseParoxysmal Nerve Pain

SCN10A SCN9A

8.89e-0516262C0751373
DiseaseNerve Pain

SCN10A SCN9A

8.89e-0516262C0751372
DiseaseNeuralgia, Ilioinguinal

SCN10A SCN9A

8.89e-0516262C0751371
DiseaseNeuralgia, Vidian

SCN10A SCN9A

8.89e-0516262C0042656
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

8.89e-0516262C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.13e-0418262HP_0002373
DiseaseBrugada syndrome

SCN10A SCN5A

1.26e-0419262MONDO_0015263
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

KCNE2 SCN5A

1.71e-0422262C1843687
DiseaseBrugada Syndrome (disorder)

SCN10A SCN5A

2.04e-0424262C1142166
Diseasecardiovascular age measurement

SCN10A SCN5A

2.99e-0429262EFO_0803380
DiseaseParoxysmal atrial fibrillation

SCN10A KCNE2 SCN5A

3.45e-04156263C0235480
Diseasefamilial atrial fibrillation

SCN10A KCNE2 SCN5A

3.45e-04156263C3468561
DiseasePersistent atrial fibrillation

SCN10A KCNE2 SCN5A

3.45e-04156263C2585653
DiseaseAtrial Fibrillation

SCN10A KCNE2 SCN5A

3.71e-04160263C0004238
Diseaseheart function measurement

SCN10A SCN5A

4.12e-0434262EFO_0004311
DiseaseQRS complex, QRS duration

SCN10A SCN5A

7.22e-0445262EFO_0005054, EFO_0005055
Diseaseapolipoprotein B to apolipoprotein A1 ratio

ABCA6 ABCA8

8.56e-0449262EFO_0021897

Protein segments in the cluster

PeptideGeneStartEntry
MYLIFYIENMQYLLI

ABCA6

1076

Q8N139
VNVLILYYAFLMEYI

DEXI

36

O95424
YYVINVEFPVVTLYM

CLSTN2

456

Q9H4D0
VVILFYGAAVYTYML

OR2T5

251

Q6IEZ7
VDAENFYYVILYLMV

KCNE2

41

Q9Y6J6
LIYFLFLLYYMVVQG

PKD1L2

2191

Q7Z442
VVILFYGAAVYTYML

OR2T29

251

Q8NH02
YQILTDFDIRFYMYE

CSNK2A2

126

P19784
YKYFQYLTFMVLVFI

TMCO5B

241

A8MYB1
EVNLYMYLYFVIFII

SCN4A

1266

P35499
YLYVAILIFFLAYVV

PKDREJ

1966

Q9NTG1
EYNLYMYIYFVIFII

SCN5A

1441

Q14524
LYMYIYFVVFIIFGS

SCN9A

1431

Q15858
NLYMYLYFVIFIIFG

SCN3A

1441

Q9NY46
IYYNMIIAYVLFYLF

SLC6A7

131

Q99884
SLYMYLYFVIFIIFG

SCN1A

1456

P35498
LYFLVFVFIYLMSYI

ABCA8

1076

O94911
YFIFEYMKENLYQLI

CILK1

76

Q9UPZ9
NVYMYLYFVIFIIFG

SCN10A

1391

Q9Y5Y9
IYLLVALFIQYINIY

TMEM39A

81

Q9NV64
MLVLLYYFYDLLVYV

SPPL2B

236

Q8TCT7
NLYMYLYFVIFIIFG

SCN2A

1446

Q99250
VIYTMLVLIFIYTYQ

PIEZO2

741

Q9H5I5
QSMLLEIIFLYYAYF

NUP188

211

Q5SRE5
DNIYMYIYFVIFIIF

SCN8A

1436

Q9UQD0
LFSLGYMYYVFLQEV

ZDHHC23

146

Q8IYP9
ISINYYFMFLYVLES

SLC9C2

641

Q5TAH2
LLYVYLLYLFFRMAQ

WFS1

506

O76024