Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloendopeptidase activity	MMP12 MMP16 MMP24	1.91e-04	120	19	3	GO:0004222
GeneOntologyMolecularFunction	ATPase activator activity	DNAJB6 DNAJA2	4.18e-04	32	19	2	GO:0001671
GeneOntologyMolecularFunction	metallopeptidase activity	MMP12 MMP16 MMP24	8.52e-04	200	19	3	GO:0008237
GeneOntologyMolecularFunction	ATPase regulator activity	DNAJB6 DNAJA2	1.19e-03	54	19	2	GO:0060590
GeneOntologyMolecularFunction	Hsp70 protein binding	DNAJB6 DNAJA2	1.62e-03	63	19	2	GO:0030544
GeneOntologyMolecularFunction	cadherin binding	MMP24 EHD1 PAK4	3.84e-03	339	19	3	GO:0045296
GeneOntologyMolecularFunction	unfolded protein binding	DNAJB6 DNAJA2	6.30e-03	126	19	2	GO:0051082
GeneOntologyMolecularFunction	endopeptidase activity	MMP12 MMP16 MMP24	7.44e-03	430	19	3	GO:0004175
GeneOntologyBiologicalProcess	collagen catabolic process	MMP12 MMP16 MMP24	1.51e-05	53	19	3	GO:0030574
GeneOntologyBiologicalProcess	chorio-allantoic fusion	DNAJB6 ERF	3.60e-05	10	19	2	GO:0060710
GeneOntologyBiologicalProcess	labyrinthine layer morphogenesis	DNAJB6 ERF	3.00e-04	28	19	2	GO:0060713
GeneOntologyBiologicalProcess	collagen metabolic process	MMP12 MMP16 MMP24	3.22e-04	148	19	3	GO:0032963
GeneOntologyBiologicalProcess	extracellular matrix organization	MMP12 DNAJB6 MMP16 MMP24	3.43e-04	377	19	4	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	MMP12 DNAJB6 MMP16 MMP24	3.46e-04	378	19	4	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	MMP12 DNAJB6 MMP16 MMP24	3.49e-04	379	19	4	GO:0045229
GeneOntologyBiologicalProcess	embryonic placenta morphogenesis	DNAJB6 ERF	4.17e-04	33	19	2	GO:0060669
GeneOntologyBiologicalProcess	cell differentiation involved in embryonic placenta development	DNAJB6 ERF	4.43e-04	34	19	2	GO:0060706
GeneOntologyBiologicalProcess	response to temperature stimulus	DNAJB6 MMP24 DNAJA2	8.69e-04	208	19	3	GO:0009266
GeneOntologyCellularComponent	ciliary pocket membrane	EHD1 EHD3	2.35e-06	3	19	2	GO:0020018
GeneOntologyCellularComponent	ciliary pocket	EHD1 EHD3	2.35e-06	3	19	2	GO:0020016
GeneOntologyCellularComponent	extracellular matrix	MMP12 MMP16 MMP24 COL6A5 HNRNPM	2.42e-04	656	19	5	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	MMP12 MMP16 MMP24 COL6A5 HNRNPM	2.45e-04	658	19	5	GO:0030312
GeneOntologyCellularComponent	nuclear inner membrane	IFFO1 PLPP6	1.30e-03	59	19	2	GO:0005637
Domain	Hemopexin_CS	MMP12 MMP16 MMP24	6.01e-07	17	19	3	IPR018486
Domain	Pept_M10A_stromelysin-type	MMP12 MMP16 MMP24	7.21e-07	18	19	3	IPR016293
Domain	EHD1/EHD3	EHD1 EHD3	9.80e-07	2	19	2	IPR029951
Domain	Peptidoglycan-bd-like	MMP12 MMP16 MMP24	1.01e-06	20	19	3	IPR002477
Domain	PG_binding_1	MMP12 MMP16 MMP24	1.01e-06	20	19	3	PF01471
Domain	HEMOPEXIN	MMP12 MMP16 MMP24	1.56e-06	23	19	3	PS00024
Domain	-	MMP12 MMP16 MMP24	1.56e-06	23	19	3	2.110.10.10
Domain	Hemopexin-like_dom	MMP12 MMP16 MMP24	1.56e-06	23	19	3	IPR000585
Domain	HEMOPEXIN_2	MMP12 MMP16 MMP24	1.56e-06	23	19	3	PS51642
Domain	Hemopexin-like_repeat	MMP12 MMP16 MMP24	1.56e-06	23	19	3	IPR018487
Domain	Hemopexin	MMP12 MMP16 MMP24	1.56e-06	23	19	3	PF00045
Domain	HX	MMP12 MMP16 MMP24	1.56e-06	23	19	3	SM00120
Domain	Pept_M10A	MMP12 MMP16 MMP24	1.56e-06	23	19	3	IPR021190
Domain	M10A_MMP	MMP12 MMP16 MMP24	1.56e-06	23	19	3	IPR033739
Domain	Peptidase_M10	MMP12 MMP16 MMP24	1.78e-06	24	19	3	PF00413
Domain	ZnMc	MMP12 MMP16 MMP24	3.21e-06	29	19	3	SM00235
Domain	Peptidase_Metallo	MMP12 MMP16 MMP24	3.21e-06	29	19	3	IPR006026
Domain	DUF3377	MMP16 MMP24	5.88e-06	4	19	2	PF11857
Domain	Pept_M10A_metallopeptidase_C	MMP16 MMP24	5.88e-06	4	19	2	IPR021805
Domain	CYSTEINE_SWITCH	MMP12 MMP16 MMP24	9.28e-06	41	19	3	PS00546
Domain	EHD_N	EHD1 EHD3	9.79e-06	5	19	2	PF16880
Domain	EHD_N	EHD1 EHD3	9.79e-06	5	19	2	IPR031692
Domain	Pept_M10_metallopeptidase	MMP12 MMP16 MMP24	1.07e-05	43	19	3	IPR001818
Domain	EF-hand_4	EHD1 EHD3	4.39e-05	10	19	2	PF12763
Domain	EH	EHD1 EHD3	5.36e-05	11	19	2	PS50031
Domain	EH	EHD1 EHD3	5.36e-05	11	19	2	SM00027
Domain	EH_dom	EHD1 EHD3	5.36e-05	11	19	2	IPR000261
Domain	-	MMP12 MMP16 MMP24	7.24e-05	81	19	3	3.40.390.10
Domain	MetalloPept_cat_dom	MMP12 MMP16 MMP24	7.24e-05	81	19	3	IPR024079
Domain	G_DYNAMIN_dom	EHD1 EHD3	8.86e-05	14	19	2	IPR030381
Domain	G_DYNAMIN_2	EHD1 EHD3	8.86e-05	14	19	2	PS51718
Domain	Dynamin_N	EHD1 EHD3	1.02e-04	15	19	2	PF00350
Domain	Dynamin_SF	EHD1 EHD3	1.02e-04	15	19	2	IPR022812
Domain	Pept_M10A_Zn_BS	MMP12 MMP16	1.02e-04	15	19	2	IPR021158
Domain	Dynamin_GTPase	EHD1 EHD3	1.02e-04	15	19	2	IPR001401
Domain	ZINC_PROTEASE	MMP12 MMP16 MMP24	1.28e-04	98	19	3	PS00142
Domain	DnaJ_domain_CS	DNAJB6 DNAJA2	3.39e-04	27	19	2	IPR018253
Domain	DnaJ	DNAJB6 DNAJA2	1.08e-03	48	19	2	PF00226
Domain	DnaJ	DNAJB6 DNAJA2	1.12e-03	49	19	2	SM00271
Domain	DNAJ_1	DNAJB6 DNAJA2	1.12e-03	49	19	2	PS00636
Domain	DNAJ_2	DNAJB6 DNAJA2	1.12e-03	49	19	2	PS50076
Domain	-	DNAJB6 DNAJA2	1.12e-03	49	19	2	1.10.287.110
Domain	DnaJ_domain	DNAJB6 DNAJA2	1.21e-03	51	19	2	IPR001623
Domain	RRM	RBM6 RBM33 HNRNPM	1.31e-03	217	19	3	SM00360
Domain	RRM_dom	RBM6 RBM33 HNRNPM	1.49e-03	227	19	3	IPR000504
Domain	RRM	RBM6 RBM33 HNRNPM	1.54e-03	230	19	3	PS50102
Domain	-	RBM6 RBM33 HNRNPM	1.83e-03	244	19	3	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	RBM6 RBM33 HNRNPM	2.14e-03	258	19	3	IPR012677
Domain	EF-hand_1	EHD1 EHD3	1.03e-02	152	19	2	PF00036
Domain	EF_Hand_1_Ca_BS	EHD1 EHD3	1.34e-02	175	19	2	IPR018247
Domain	EF_HAND_1	EHD1 EHD3	1.80e-02	204	19	2	PS00018
Domain	EF_HAND_2	EHD1 EHD3	2.27e-02	231	19	2	PS50222
Domain	EF_hand_dom	EHD1 EHD3	2.29e-02	232	19	2	IPR002048
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP12 MMP16 MMP24	5.22e-06	29	17	3	MM15981
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP12 MMP16 MMP24	5.80e-06	30	17	3	M39652
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	MMP12 MMP16 MMP24 COL6A5	8.90e-06	114	17	4	MM14571
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	MMP12 MMP16 MMP24 COL6A5	2.01e-05	140	17	4	M587
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	MMP12 MMP16 MMP24	2.14e-05	46	17	3	M46450
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MMP12 MMP16 MMP24 COL6A5	2.16e-04	258	17	4	MM14572
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MMP12 MMP16 MMP24 COL6A5	3.84e-04	300	17	4	M610
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP16 MMP24	7.07e-04	33	17	2	M26976
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP16 MMP24	9.38e-04	38	17	2	MM14611
Pathway	WP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES	CPT1C PLPP6 EHD1 EHD3	9.45e-04	381	17	4	M48063
Pathway	REACTOME_COLLAGEN_DEGRADATION	MMP12 COL6A5	1.82e-03	53	17	2	MM14566
Pathway	REACTOME_COLLAGEN_DEGRADATION	MMP12 COL6A5	2.64e-03	64	17	2	M26953
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP12 MMP16 MMP24	7.71e-08	16	19	3	10949577
Pubmed	Matrix metalloproteinases.	MMP12 MMP16 MMP24	2.11e-07	22	19	3	10419448
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP12 MMP16 MMP24	2.11e-07	22	19	3	23421805
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP12 MMP16 MMP24	2.78e-07	24	19	3	15734845
Pubmed	Zic2 promotes tumor growth and metastasis via PAK4 in hepatocellular carcinoma.	ZIC2 PAK4	2.83e-07	2	19	2	28577975
Pubmed	SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.	EHD1 EHD3	2.83e-07	2	19	2	26226295
Pubmed	Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.	EHD1 EHD3	8.48e-07	3	19	2	24019528
Pubmed	EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.	EHD1 EHD3	8.48e-07	3	19	2	12121420
Pubmed	Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.	EHD1 EHD3	8.48e-07	3	19	2	25686250
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	MMP12 MMP16 MMP24	9.76e-07	36	19	3	20587546
Pubmed	Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane.	EHD1 EHD3	1.70e-06	4	19	2	15020713
Pubmed	Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans.	EHD1 EHD3	1.70e-06	4	19	2	17233914
Pubmed	Interactions between EHD proteins and Rab11-FIP2: a role for EHD3 in early endosomal transport.	EHD1 EHD3	1.70e-06	4	19	2	16251358
Pubmed	EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.	EHD1 EHD3	1.70e-06	4	19	2	10673336
Pubmed	Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).	MMP16 MMP24	1.70e-06	4	19	2	35062057
Pubmed	C-terminal EH-domain-containing proteins: consensus for a role in endocytic trafficking, EH?	EHD1 EHD3	1.70e-06	4	19	2	16155252
Pubmed	Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function.	EHD1 EHD3	1.70e-06	4	19	2	29212907
Pubmed	EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.	EHD1 EHD3	1.70e-06	4	19	2	27189942
Pubmed	EH domain proteins regulate cardiac membrane protein targeting.	EHD1 EHD3	2.82e-06	5	19	2	20489164
Pubmed	mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.	MMP16 MMP24	2.82e-06	5	19	2	12661033
Pubmed	MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.	MMP16 MMP24	2.82e-06	5	19	2	29196321
Pubmed	MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.	EHD1 EHD3	4.24e-06	6	19	2	19864458
Pubmed	Membrane-type matrix metalloproteinases: Their functions and regulations.	MMP16 MMP24	5.93e-06	7	19	2	25794647
Pubmed	Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases.	MMP16 MMP24	5.93e-06	7	19	2	12879005
Pubmed	Myosin Vb interacts with Rab8a on a tubular network containing EHD1 and EHD3.	EHD1 EHD3	7.90e-06	8	19	2	17507647
Pubmed	Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29.	EHD1 EHD3	1.02e-05	9	19	2	11423532
Pubmed	The endocytic recycling regulatory protein EHD1 Is required for ocular lens development.	EHD1 EHD3	1.55e-05	11	19	2	26455409
Pubmed	Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes.	MMP12 MMP16	1.55e-05	11	19	2	10949161
Pubmed	Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.	MMP12 MMP16	3.38e-05	16	19	2	37701782
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	DNAJB6 DNAJA2 HNRNPM	3.73e-05	120	19	3	27320910
Pubmed	PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.	IFFO1 PAK4 ERF	4.73e-05	130	19	3	26598620
Pubmed	Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.	DNAJB6 DNAJA2	6.49e-05	22	19	2	11147971
Pubmed	The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.	DNAJB6 DNAJA2	7.10e-05	23	19	2	21231916
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	DNAJB6 DNAJA2 HNRNPM	8.14e-05	156	19	3	32850835
Pubmed	Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ERα) and Biochemical Characterization of the ERα-Hsp70 Interaction.	DNAJB6 DNAJA2	8.42e-05	25	19	2	27483141
Pubmed	Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.	DNAJB6 RBM33 DNAJA2 HNRNPM	1.03e-04	463	19	4	27503909
Pubmed	Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.	EHD1 EHD3	1.06e-04	28	19	2	26884322
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	RBM6 RBM33 HNRNPM	1.24e-04	180	19	3	35198878
Pubmed	UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.	DNAJB6 DNAJA2 PAK4 HNRNPM	1.29e-04	491	19	4	36273042
Pubmed	Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.	DNAJA2 HNRNPM	1.57e-04	34	19	2	16611982
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DNAJB6 RBM33 PAK4 ERF HNRNPM	1.92e-04	1038	19	5	26673895
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	DNAJB6 COL6A5 DNAJA2 HNRNPM	2.10e-04	558	19	4	27591049
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DNAJB6 DNAJA2 ZIC2 ERF HNRNPM	2.69e-04	1116	19	5	31753913
Pubmed	Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.	RBM6 CCDC85A	2.88e-04	46	19	2	21102462
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DNAJB6 RBM33 DNAJA2 HNRNPM	3.49e-04	638	19	4	33239621
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	DNAJB6 DNAJA2 EHD1 HNRNPM	3.68e-04	647	19	4	26618866
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	DNAJB6 DNAJA2 ERF HNRNPM	3.86e-04	655	19	4	35819319
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	IFFO1 DNAJA2 HNRNPM	4.74e-04	284	19	3	29459677
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DNAJB6 EHD1 PAK4 HNRNPM	5.17e-04	708	19	4	39231216
Interaction	MMP16 interactions	MMP12 MMP16 MMP24	5.75e-07	18	19	3	int:MMP16
Interaction	SCP2D1 interactions	EHD1 EHD3	2.52e-06	3	19	2	int:SCP2D1
Interaction	MMP1 interactions	MMP12 MMP16 MMP24	5.41e-06	37	19	3	int:MMP1
Interaction	EHD1 interactions	DNAJB6 DNAJA2 EHD1 EHD3	1.25e-05	157	19	4	int:EHD1
Interaction	RBSN interactions	IFFO1 EHD1 EHD3	2.99e-05	65	19	3	int:RBSN
Interaction	EHD2 interactions	DNAJB6 EHD1 EHD3	3.58e-05	69	19	3	int:EHD2
Interaction	MMP20 interactions	MMP16 MMP24	3.77e-05	10	19	2	int:MMP20
Interaction	MMP17 interactions	MMP16 MMP24	3.77e-05	10	19	2	int:MMP17
Interaction	MMP27 interactions	MMP16 MMP24	4.61e-05	11	19	2	int:MMP27
Interaction	MMP12 interactions	MMP12 MMP16	4.61e-05	11	19	2	int:MMP12
Interaction	MMP11 interactions	MMP16 MMP24	5.53e-05	12	19	2	int:MMP11
Interaction	RAB11FIP2 interactions	CCDC85A EHD1 EHD3	6.22e-05	83	19	3	int:RAB11FIP2
Interaction	KISS1 interactions	MMP16 MMP24	1.14e-04	17	19	2	int:KISS1
Interaction	MMP24 interactions	MMP16 MMP24	1.43e-04	19	19	2	int:MMP24
Interaction	NEK9 interactions	EPOP DNAJA2 PAK4	1.48e-04	111	19	3	int:NEK9
Interaction	EHD4 interactions	DNAJA2 EHD1 EHD3	2.25e-04	128	19	3	int:EHD4
Interaction	MMP8 interactions	MMP16 MMP24	2.49e-04	25	19	2	int:MMP8
Interaction	MMP10 interactions	MMP16 MMP24	3.61e-04	30	19	2	int:MMP10
Interaction	MMP13 interactions	MMP16 MMP24	3.85e-04	31	19	2	int:MMP13
Interaction	EHD3 interactions	EHD1 EHD3	4.11e-04	32	19	2	int:EHD3
Interaction	OXSM interactions	DNAJB6 HNRNPM	4.92e-04	35	19	2	int:OXSM
Interaction	SNW1 interactions	RBM6 RBM33 EHD1 PAK4 HNRNPM	5.20e-04	747	19	5	int:SNW1
Interaction	CIAO2A interactions	DNAJB6 PLPP6 ERF	5.44e-04	173	19	3	int:CIAO2A
Cytoband	7q36.3	DNAJB6 RBM33	4.45e-05	24	19	2	7q36.3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	DNAJB6 RBM33	1.96e-03	159	19	2	chr7q36
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	CPT1C PAK4 ERF	1.24e-02	1192	19	3	chr19q13
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP12 MMP16 MMP24	9.25e-07	24	15	3	891
GeneFamily	RNA binding motif containing	RBM6 RBM33 HNRNPM	6.61e-04	213	15	3	725
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	DNAJB6 DNAJA2	7.39e-04	49	15	2	584
GeneFamily	EF-hand domain containing	EHD1 EHD3	1.38e-02	219	15	2	863
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	RBM6 PLPP6 EHD1	5.73e-05	179	19	3	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMP16 CCDC85A EHD3	6.62e-05	188	19	3	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMP16 CCDC85A EHD3	6.83e-05	190	19	3	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MMP24 CCDC85A EHD1	7.61e-05	197	19	3	e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MMP24 CCDC85A EHD1	7.61e-05	197	19	3	69d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPOP PLPP6 EHD1	7.84e-05	199	19	3	26bb93347e6722abd174dfa62cab692ce2b7eb23
Drug	MMI270	MMP12 MMP16 MMP24	3.99e-07	18	19	3	CID000446504
Drug	DA-125	MMP12 MMP16 MMP24	1.27e-06	26	19	3	CID000114758
Drug	mercuric acetate	MMP12 MMP16 MMP24	1.97e-06	30	19	3	CID000015337
Drug	Batimastat	MMP12 MMP16	1.98e-06	3	19	2	DB03880
Drug	malolactomycin D	MMP12 MMP16 MMP24	2.41e-06	32	19	3	CID006449115
Drug	latanoprost acid	MMP12 MMP16 MMP24	4.77e-06	40	19	3	CID006441636
Drug	AC1L9M3B	MMP12 MMP16 MMP24	1.72e-05	61	19	3	CID000448562
Drug	4-aminophenyl	MMP12 MMP16 MMP24	1.81e-05	62	19	3	CID000181201
Drug	Marimastat	MMP12 MMP16	1.84e-05	8	19	2	DB00786
Drug	diacerein	MMP12 MMP16 MMP24	1.90e-05	63	19	3	CID000026248
Drug	AC1L1GXT	MMP12 MMP16 MMP24	3.08e-05	74	19	3	CID000003890
Drug	A0395	MMP12 MMP16 MMP24	3.20e-05	75	19	3	CID009906466
Drug	AC1NSU5S	MMP12 MMP16 MMP24	3.20e-05	75	19	3	CID005316299
Drug	1,10-phenanthroline	MMP12 MMP16 MMP24 ERF	6.24e-05	267	19	4	CID000001318
Drug	pirfenidone	MMP12 MMP16 MMP24	1.97e-04	138	19	3	CID000040632
Drug	Pro-leu-gly	MMP16 MMP24	2.12e-04	26	19	2	CID000169533
Disease	clear cell renal cell carcinoma (is_marker_for)	MMP12 PAK4	2.05e-04	33	19	2	DOID:4467 (is_marker_for)
Disease	biological sex	MMP16 CCDC85A	9.48e-03	230	19	2	PATO_0000047
Disease	Cleft palate, cleft lip	MMP16 PLPP6	1.37e-02	279	19	2	EFO_0003959, HP_0000175

Protein segments in the cluster

Peptide	Gene	Start	Entry
GGGPSGSGGGSHFSF	ERF	291	P50548
SGGGGESDGFFHPEG	RBM33	991	Q96EV2
GPGSGIGGDAHFDED	MMP12	186	P39900
SGFHGDSSPFDGEGG	MMP24	226	Q9Y5R2
GGSFAGSFGGAGGHA	HNRNPM	631	P52272
GPLGDSLGGDHFAGG	IFFO1	21	Q0D2I5
GGGFGPADDHGYGVS	CPT1C	706	Q8TCG5
EGSGGGGGMDDIFSH	DNAJA2	76	O60884
EGLNGGGGGGSHFDS	DNAJB6	71	O75190
GGGGGSHFDSPFEFG	DNAJB6	76	O75190
RGEEEEGGGGFPHFG	EPOP	116	A6NHQ4
FSGPKGGHGDDGIDG	COL6A5	1456	A8TX70
YGGSPDHKHGGGSGG	CCDC85A	366	Q96PX6
PFGHGYGEGAGEGID	EHD1	421	Q9H4M9
GRFAGHSEAGGGSGD	PAK4	136	O96013
RGGEGPGHDFRGGDF	RBM6	86	P78332
GGAFEGTLHGPFGHG	EHD3	411	Q9NZN3
PFGHGYGEGAGEGID	EHD3	421	Q9NZN3
GFHGDSSPFDGEGGF	MMP16	191	P51512
SPAHGGGGGGSRFEF	PLPP6	26	Q8IY26
FGDSAPGGGQHGLFG	ZIC2	126	O95409