Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

RAB6D DNAH3 ABCA12 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV SHOC1 HSP90AB2P ABCC2 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9 RAB26 RAB5B RAB6A

4.00e-0877516924GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

RAB6D DNAH3 ABCA12 TRPM2 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV SHOC1 HSP90AB2P ABCC2 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9 RAB26 RAB5B RAB6A

4.28e-0883916925GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

RAB6D DNAH3 ABCA12 TRPM2 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV SHOC1 HSP90AB2P ABCC2 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9 RAB26 RAB5B RAB6A

4.38e-0884016925GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

RAB6D DNAH3 ABCA12 TRPM2 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV SHOC1 HSP90AB2P ABCC2 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9 RAB26 RAB5B RAB6A

4.38e-0884016925GO:0016818
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

3.21e-07181695GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

3.44e-06281695GO:0051959
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPV1 TRPM2 GRIA1 SLC3A2 CUL5 PKD1 TRPM1 ATP2B1 MCOLN2

5.68e-061511699GO:0015085
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

1.43e-05371695GO:0045505
GeneOntologyMolecularFunctionmyosin V binding

GRIA1 RAB6B RAB3C RAB6A

2.16e-05201694GO:0031489
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 ABCA12 ABCC11 YTHDC2 SRCAP FANCM SHOC1 HSP90AB2P ABCC2 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9

2.43e-0544116914GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 ABCA12 ABCC11 YTHDC2 SRCAP FANCM DNAH17 SHOC1 HSP90AB2P ABCC2 DSCC1 DNAH5 DNAH6 DHX34 ATP2B1 DNAH9

6.90e-0561416916GO:0140657
GeneOntologyMolecularFunctioncalcium channel activity

TRPV1 TRPM2 GRIA1 CUL5 PKD1 TRPM1 MCOLN2

1.15e-041291697GO:0005262
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPV1 TRPM2 GRIA1 MCOLN2

1.30e-04311694GO:0099604
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

3.18e-04701695GO:0003777
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

TRPV1 TRPM2 MCOLN2

4.43e-04181693GO:0015278
GeneOntologyMolecularFunctionGTPase activity

RAB6D RAB6B RAB3C RAB6C RHEB RRAGC RHOV RAB26 RAB5B RAB6A

6.73e-0434116910GO:0003924
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

7.00e-0451692GO:0140444
GeneOntologyMolecularFunctionmyosin binding

MYOC GRIA1 RAB6B RAB3C RAB6A

7.78e-04851695GO:0017022
GeneOntologyBiologicalProcessmicrotubule-based movement

ADCY10 CFAP47 DNAH3 HIF1A CFAP73 HOATZ LAMP1 CFAP65 AGBL4 RGN DNAH17 SYNE2 WDR35 PRKCZ DNAH5 DNAH6 DNAH9 RAB6A ARHGAP21

2.47e-0849316919GO:0007018
GeneOntologyBiologicalProcessmicrotubule-based process

ADCY10 CFAP47 FLNA DNAH3 HIF1A CFAP73 HOATZ LAMP1 CUL7 RAB6C CFAP65 AGBL4 RGN BRCA1 DNAH17 SYNE2 PKD1 WDR35 PRKCZ DNAH5 DNAH6 DNAH9 RAB6A ARHGAP21

5.86e-06105816924GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based transport

ADCY10 HIF1A LAMP1 AGBL4 SYNE2 WDR35 PRKCZ DNAH5 DNAH9 RAB6A ARHGAP21

7.98e-0625316911GO:0099111
GeneOntologyBiologicalProcesscilium movement

ADCY10 CFAP47 DNAH3 CFAP73 HOATZ CFAP65 RGN DNAH17 DNAH5 DNAH6 DNAH9

1.07e-0526116911GO:0003341
GeneOntologyBiologicalProcessorganelle transport along microtubule

HIF1A LAMP1 AGBL4 SYNE2 PRKCZ RAB6A ARHGAP21

1.51e-05971697GO:0072384
GeneOntologyBiologicalProcessintermediate filament organization

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

3.49e-05751696GO:0045109
GeneOntologyBiologicalProcesscilium movement involved in cell motility

CFAP47 DNAH3 HOATZ CFAP65 RGN DNAH17 DNAH5 DNAH6 DNAH9

6.07e-052101699GO:0060294
GeneOntologyBiologicalProcessnodal receptor complex assembly

LEFTY2 LEFTY1

6.67e-0521692GO:0038099
GeneOntologyBiologicalProcessnegative regulation of nodal receptor complex assembly

LEFTY2 LEFTY1

6.67e-0521692GO:1900124
GeneOntologyBiologicalProcessregulation of nodal receptor complex assembly

LEFTY2 LEFTY1

6.67e-0521692GO:1900123
GeneOntologyBiologicalProcesscilium-dependent cell motility

CFAP47 DNAH3 HOATZ CFAP65 RGN DNAH17 DNAH5 DNAH6 DNAH9

7.27e-052151699GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

CFAP47 DNAH3 HOATZ CFAP65 RGN DNAH17 DNAH5 DNAH6 DNAH9

7.27e-052151699GO:0001539
GeneOntologyBiologicalProcessintracellular transport

RAB6D FLNA HIF1A PRR5L CLTCL1 ABCA12 SYNE1 EI24 LAMP1 SEC31A RAB6B SDAD1 RAB6C WDR91 AGBL4 BRCA1 TMEM87B SYNE2 ITSN2 PKD1 WDR35 LRP2 SERAC1 PRKCZ RAB5B RAB6A ARHGAP21

8.56e-05149616927GO:0046907
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

KALRN GRIA1 PLCB1 TRPM1 HOMER2

1.22e-04591695GO:0007215
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

1.65e-04991696GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

1.75e-041001696GO:0045103
GeneOntologyBiologicalProcessintra-Golgi vesicle-mediated transport

RAB6D RAB6B RAB6C RAB6A

1.87e-04351694GO:0006891
GeneOntologyBiologicalProcesscerebral cortex development

FLNA HIF1A GRIA1 CUL5 SYNE2 PLCB1 NCOA1

2.13e-041471697GO:0021987
GeneOntologyBiologicalProcesstransport along microtubule

HIF1A LAMP1 AGBL4 SYNE2 WDR35 PRKCZ RAB6A ARHGAP21

2.26e-041971698GO:0010970
GeneOntologyBiologicalProcesscytosolic transport

RAB6D CLTCL1 LAMP1 RAB6B RAB6C TMEM87B RAB6A

2.41e-041501697GO:0016482
GeneOntologyBiologicalProcessaxoneme assembly

CFAP47 CFAP73 HOATZ CFAP65 DNAH17 DNAH5

2.79e-041091696GO:0035082
GeneOntologyBiologicalProcessretrograde transport, endosome to Golgi

RAB6D CLTCL1 RAB6B RAB6C TMEM87B RAB6A

2.79e-041091696GO:0042147
GeneOntologyBiologicalProcessendosomal transport

RAB6D FLNA CLTCL1 RAB6B RAB6C WDR91 TMEM87B ITSN2 LRP2 RAB6A

3.19e-0432016910GO:0016197
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

1.65e-06251725GO:0005858
GeneOntologyCellularComponentmotile cilium

ADCY10 CFAP47 DNAH3 HIF1A CFAP73 CFAP65 MROH2B DNAH17 PKD1 DNAH5 DNAH6 DNAH9 BRWD1

8.07e-0635517213GO:0031514
GeneOntologyCellularComponentcell projection membrane

TRPV1 GRIA1 ITGA3 KCNH1 SYNE2 PKD1 LRP2 FGD5 ABCC2 PLEKHO1 ATP2B1 UTRN BRWD1

6.09e-0543117213GO:0031253
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

8.12e-05541725GO:0030286
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH5 DNAH9

1.14e-04121723GO:0036157
GeneOntologyCellularComponenttransport vesicle membrane

CLTCL1 ABCA12 GRIA1 LAMP1 SEC31A RAB3C FER1L5 ATP2B1 RAB26 RAB5B

1.63e-0429317210GO:0030658
GeneOntologyCellularComponentcytoplasmic region

DNAH3 HIF1A CFAP73 AGBL4 DNAH17 WDR35 PRKCZ DNAH5 DNAH6 DNAH9 BRWD1

2.03e-0436017211GO:0099568
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH3 HIF1A CFAP73 AGBL4 DNAH17 WDR35 DNAH5 DNAH6 DNAH9 BRWD1

3.07e-0431717210GO:0032838
GeneOntologyCellularComponentaxoneme

DNAH3 CFAP73 DNAH17 WDR35 DNAH5 DNAH6 DNAH9 BRWD1

3.25e-042071728GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 CFAP73 DNAH17 WDR35 DNAH5 DNAH6 DNAH9 BRWD1

3.36e-042081728GO:0097014
GeneOntologyCellularComponentdendritic spine membrane

TRPV1 GRIA1 ATP2B1

4.08e-04181723GO:0032591
GeneOntologyCellularComponentcilium

ADCY10 CFAP47 DNAH3 HIF1A CFAP73 MYOC HOATZ CFAP65 AGBL4 MROH2B DNAH17 PKD1 WDR35 SCLT1 DNAH5 DNAH6 DNAH9 BRWD1

4.50e-0489817218GO:0005929
GeneOntologyCellularComponentcytoplasmic vesicle membrane

MRC1 CLTCL1 ABCA12 TRPM2 ABCC11 GRIA1 LAMP1 SEC31A RAB3C CFAP65 WDR91 RHOV KCNH1 PKD1 OSBPL9 LRP2 FER1L5 ATP2B1 RAB26 RAB5B RAB6A ARHGAP21 MCOLN2

4.62e-04130717223GO:0030659
GeneOntologyCellularComponentvesicle membrane

MRC1 CLTCL1 ABCA12 TRPM2 ABCC11 GRIA1 LAMP1 SEC31A RAB3C CFAP65 WDR91 RHOV KCNH1 PKD1 OSBPL9 LRP2 FER1L5 ATP2B1 RAB26 RAB5B RAB6A ARHGAP21 MCOLN2

5.58e-04132517223GO:0012506
GeneOntologyCellularComponentfilopodium membrane

ITGA3 SYNE2 UTRN

6.53e-04211723GO:0031527
GeneOntologyCellularComponentexocytic vesicle membrane

GRIA1 LAMP1 RAB3C FER1L5 ATP2B1 RAB26 RAB5B

7.17e-041791727GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

GRIA1 LAMP1 RAB3C FER1L5 ATP2B1 RAB26 RAB5B

7.17e-041791727GO:0030672
GeneOntologyCellularComponentleading edge membrane

TRPV1 GRIA1 KCNH1 SYNE2 FGD5 PLEKHO1 ATP2B1

1.81e-032101727GO:0031256
HumanPhenoRetinal arterial occlusion

CYP1B1 MYOC ADA2

1.31e-055573HP:0025326
DomainSpectrin

DRP2 TRIO KALRN SYNE1 SPTB SYNE2 UTRN

7.71e-10231647PF00435
DomainSpectrin_repeat

DRP2 TRIO KALRN SYNE1 SPTB SYNE2 UTRN

4.70e-09291647IPR002017
DomainSPEC

DRP2 TRIO KALRN SYNE1 SPTB SYNE2 UTRN

9.91e-09321647SM00150
DomainSpectrin/alpha-actinin

DRP2 TRIO KALRN SYNE1 SPTB SYNE2 UTRN

9.91e-09321647IPR018159
Domain-

ADCY10 DNAH3 ABCA12 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV ABCC2 DNAH5 DNAH6 DHX34 DNAH9 RAB26 RAB5B RAB6A CHST3

6.45e-07746164223.40.50.300
DomainACTININ_2

FLNA SYNE1 SPTB SYNE2 UTRN

1.45e-06231645PS00020
DomainACTININ_1

FLNA SYNE1 SPTB SYNE2 UTRN

1.45e-06231645PS00019
DomainActinin_actin-bd_CS

FLNA SYNE1 SPTB SYNE2 UTRN

1.45e-06231645IPR001589
DomainKeratin_I

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

2.24e-06441646IPR002957
DomainP-loop_NTPase

ADCY10 DNAH3 ABCA12 ABCC11 YTHDC2 SRCAP FANCM RAB6B RAB3C RAB6C RHEB RRAGC RHOV ABCC2 DNAH5 DNAH6 DHX34 DNAH9 RAB26 RAB5B RAB6A CHST3

5.23e-0684816422IPR027417
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644IPR013602
DomainDHC_N2

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644IPR011704
DomainMT

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644PF12777
DomainAAA_8

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644PF12780
DomainAAA_5

DNAH3 DNAH5 DNAH6 DNAH9

5.36e-06141644PF07728
DomainDHC_fam

DNAH3 DNAH5 DNAH6 DNAH9

7.25e-06151644IPR026983
DomainDynein_heavy

DNAH3 DNAH5 DNAH6 DNAH9

7.25e-06151644PF03028
DomainDynein_heavy_dom

DNAH3 DNAH5 DNAH6 DNAH9

7.25e-06151644IPR004273
DomainPAS

HIF1A PASK PER3 KCNH1 NCOA1

8.16e-06321645SM00091
DomainPAS

HIF1A PASK PER3 KCNH1 NCOA1

1.11e-05341645PS50112
DomainPAS

HIF1A PASK PER3 KCNH1 NCOA1

1.11e-05341645IPR000014
DomainPH_dom-like

TRIO KALRN TNS2 ARHGAP12 ITSN2 OSBPL9 PLCB1 FGD5 PLEKHM3 PLCL1 PLEKHO1 HOMER2 ARHGAP21 ARAP2

2.46e-0542616414IPR011993
DomainRas

RAB6B RAB3C RAB6C RHEB RHOV RAB26 RAB5B RAB6A

2.71e-051361648PF00071
DomainCH

CFAP47 FLNA SYNE1 SPTB SYNE2 UTRN

3.45e-05701646PF00307
DomainPH

TRIO KALRN ARHGAP12 ITSN2 OSBPL9 FGD5 PLEKHM3 PLEKHO1 ARHGAP21 ARAP2

3.57e-0522916410PF00169
DomainPH

TRIO KALRN ARHGAP12 ITSN2 OSBPL9 FGD5 PLEKHM3 PLCL1 PLEKHO1 ARHGAP21 ARAP2

3.58e-0527816411SM00233
DomainPH_DOMAIN

TRIO KALRN ARHGAP12 ITSN2 OSBPL9 FGD5 PLEKHM3 PLCL1 PLEKHO1 ARHGAP21 ARAP2

3.70e-0527916411PS50003
Domain-

CFAP47 FLNA SYNE1 SPTB SYNE2 UTRN

3.74e-057116461.10.418.10
DomainPH_domain

TRIO KALRN ARHGAP12 ITSN2 OSBPL9 FGD5 PLEKHM3 PLCL1 PLEKHO1 ARHGAP21 ARAP2

3.82e-0528016411IPR001849
DomainIF

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

4.05e-05721646PS00226
Domain-

TRIO KALRN TNS2 ARHGAP12 ITSN2 OSBPL9 FGD5 PLEKHM3 PLCL1 PLEKHO1 HOMER2 ARHGAP21 ARAP2

4.30e-05391164132.30.29.30
DomainRAB

RAB6B RAB3C RAB6C RAB26 RAB5B RAB6A

4.38e-05731646PS51419
DomainCH

CFAP47 FLNA SYNE1 SPTB SYNE2 UTRN

4.38e-05731646PS50021
DomainFilament

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

4.38e-05731646PF00038
DomainCH-domain

CFAP47 FLNA SYNE1 SPTB SYNE2 UTRN

5.11e-05751646IPR001715
DomainIF

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

5.50e-05761646IPR001664
DomainPAS

HIF1A PASK KCNH1 NCOA1

6.28e-05251644PF00989
DomainPAS_fold

HIF1A PASK KCNH1 NCOA1

6.28e-05251644IPR013767
DomainLRDF

LEFTY2 LEFTY1

7.66e-0521642IPR003942
DomainSmall_GTPase

RAB6B RAB3C RAB6C RHEB RHOV RAB26 RAB5B RAB6A

8.58e-051601648IPR001806
DomainGFP-like

SVEP1 EGFL6 ADGRL4

1.04e-04111643IPR023413
Domain-

SVEP1 EGFL6 ADGRL4

1.04e-041116432.40.155.10
DomainSmall_GTP-bd_dom

RAB6B RAB3C RAB6C RHEB RHOV RAB26 RAB5B RAB6A

1.16e-041671648IPR005225
DomainCH

FLNA SYNE1 SPTB SYNE2 UTRN

2.65e-04651645SM00033
DomainAAA

DNAH3 ABCA12 ABCC11 ABCC2 DNAH5 DNAH6 DNAH9

2.84e-041441647SM00382
DomainAAA+_ATPase

DNAH3 ABCA12 ABCC11 ABCC2 DNAH5 DNAH6 DNAH9

2.84e-041441647IPR003593
DomainFilament

KRT31 KRT33A KRT27 KRT33B KRT25

4.01e-04711645SM01391
DomainKASH

SYNE1 SYNE2

4.55e-0441642IPR012315
DomainKASH

SYNE1 SYNE2

4.55e-0441642PS51049
DomainKASH

SYNE1 SYNE2

4.55e-0441642SM01249
DomainKASH

SYNE1 SYNE2

4.55e-0441642PF10541
DomainERCC4

EME1 FANCM

7.53e-0451642SM00891
DomainERCC4_domain

EME1 FANCM

7.53e-0451642IPR006166
DomainERCC4

EME1 FANCM

7.53e-0451642PF02732
DomainEGF_CA

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

9.64e-04861645PF07645
DomainPAS_fold_3

HIF1A PER3 KCNH1

1.03e-03231643IPR013655
DomainPAS_3

HIF1A PER3 KCNH1

1.03e-03231643PF08447
DomainEF-hand_dom_typ1

DRP2 UTRN

1.12e-0361642IPR015153
DomainEF-hand_dom_typ2

DRP2 UTRN

1.12e-0361642IPR015154
DomainEF-hand_2

DRP2 UTRN

1.12e-0361642PF09068
DomainEF-hand_3

DRP2 UTRN

1.12e-0361642PF09069
DomainPAS-assoc_C

HIF1A PER3 KCNH1

1.17e-03241643IPR000700
DomainPAC

HIF1A PER3 KCNH1

1.49e-03261643IPR001610
DomainPAC

HIF1A PER3 KCNH1

1.49e-03261643PS50113
DomainPAC

HIF1A PER3 KCNH1

1.49e-03261643SM00086
DomainTLV_coat

ERVV-2 ERVV-1

1.56e-0371642PF00429
DomainEGF_Ca-bd_CS

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

1.65e-03971645IPR018097
DomainEGF_CA

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

1.81e-03991645PS01187
DomainASX_HYDROXYL

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

1.89e-031001645PS00010
DomainCullin_neddylation_domain

CUL7 CUL5

2.07e-0381642IPR019559
DomainDHC_N1

DNAH5 DNAH9

2.07e-0381642PF08385
DomainCullin_Nedd8

CUL7 CUL5

2.07e-0381642PF10557
DomainCullin_Nedd8

CUL7 CUL5

2.07e-0381642SM00884
DomainTLV/ENV_coat_polyprotein

ERVV-2 ERVV-1

2.07e-0381642IPR018154
DomainDynein_heavy_dom-1

DNAH5 DNAH9

2.07e-0381642IPR013594
DomainIntermediate_filament_CS

KRT31 KRT33A KRT33B KRT34

2.28e-03631644IPR018039
DomainEGF-type_Asp/Asn_hydroxyl_site

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

2.44e-031061645IPR000152
DomainCullin_homology

CUL7 CUL5

2.65e-0391642IPR016158
DomainRhoGEF

TRIO KALRN ITSN2 FGD5

3.02e-03681644SM00325
DomainCullin

CUL7 CUL5

3.29e-03101642PF00888
DomainPAS_9

PASK KCNH1

3.29e-03101642PF13426
DomainCULLIN_2

CUL7 CUL5

3.29e-03101642PS50069
DomainCullin_N

CUL7 CUL5

3.29e-03101642IPR001373
DomainCULLIN_1

CUL7 CUL5

3.29e-03101642PS01256
DomainC2_dom

TNS2 TC2N ITSN2 PLCB1 PLCL1 FER1L5

3.30e-031641646IPR000008
DomainIon_trans_dom

TRPV1 TRPM2 KCNH1 TRPM1 MCOLN2

3.34e-031141645IPR005821
DomainIon_trans

TRPV1 TRPM2 KCNH1 TRPM1 MCOLN2

3.34e-031141645PF00520
DomainRhoGEF

TRIO KALRN ITSN2 FGD5

3.35e-03701644PF00621
DomainDH_2

TRIO KALRN ITSN2 FGD5

3.35e-03701644PS50010
Domain-

TRIO KALRN ITSN2 FGD5

3.53e-037116441.20.900.10
DomainDH-domain

TRIO KALRN ITSN2 FGD5

3.53e-03711644IPR000219
DomainPKD_channel

PKD1 MCOLN2

4.00e-03111642PF08016
DomainPKD1_2_channel

PKD1 MCOLN2

4.00e-03111642IPR013122
DomainEGF_CA

SVEP1 EGFL6 ADGRL4 FAT1 LRP2

4.46e-031221645SM00179
DomainDEAH_ATP_HELICASE

YTHDC2 FANCM DHX34

4.48e-03381643PS00690
DomainDUF4599

SPATA31C2 SPATA31C1

4.77e-03121642PF15371
DomainDUF4599

SPATA31C2 SPATA31C1

4.77e-03121642IPR027970
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

5.28e-06271365M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

5.57e-05431365M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

6.96e-05451365M47670
PathwayREACTOME_TRP_CHANNELS

TRPV1 TRPM2 TRPM1 MCOLN2

1.42e-04281364MM14943
PathwayREACTOME_TRP_CHANNELS

TRPV1 TRPM2 TRPM1 MCOLN2

1.42e-04281364M27241
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

1.92e-04871366MM15351
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MRPS31 FLNA EME1 CLTCL1 KRT31 KRT33A KRT33B KRT34 SYNE1 GRIA1 SRP72 SRCAP PRPF8 RAB3C CHRNB3 SLC3A2 BRCA1 SACS ARHGAP12 SYNE2 ITSN2 OGDHL ABCC2 DNAH6 ATP2B1 ARHGAP21 ZNF292

3.17e-0914421732735575683
Pubmed

Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation.

KRT31 KRT33A KRT33B KRT34

8.80e-096173410559501
Pubmed

Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

KRT31 KRT33A KRT33B KRT34

7.31e-08917349756910
Pubmed

Human hair keratins.

KRT31 KRT33A KRT33B KRT34

7.31e-08917347686952
Pubmed

The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.

KRT31 KRT33A KRT33B KRT34

1.21e-0710173410391933
Pubmed

The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.

KRT33A KRT27 KRT33B KRT25

2.84e-0712173415617563
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH6 DNAH9

4.82e-074173311175280
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH17 DNAH5 DNAH6

5.69e-071417349373155
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPV1 TRPM2 PKD1 TRPM1 MCOLN2

6.09e-0733173519834762
Pubmed

New consensus nomenclature for mammalian keratins.

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

7.46e-0763173616831889
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLNA TRIO KALRN SYNE1 SPTB LARS1 GRIA1 SRP72 YTHDC2 SLC3A2 CUL5 AGBL4 USP5 SACS ITSN2 OSBPL9 OGDHL PLCL1 DNAH6 ATP2B1 UTRN ARHGAP21 TARS1

7.67e-0714311732337142655
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

DRP2 ITGA3 SLC3A2 RHEB UBE2N SYNE2 ITSN2 PLCB1 NCOA1 FGD5 FER1L5 ATP2B1 TARBP1 RAB6A KNL1

8.06e-076381731531182584
Pubmed

Lineage-specific functions of TET1 in the postimplantation mouse embryo.

LEFTY2 LEFTY1 TET1

1.20e-065173328504700
Pubmed

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity.

RAB6D RAB6B RAB3C RAB26 RAB5B RAB6A

1.65e-0672173616923123
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPV1 TRPM2 PKD1 TRPM1 MCOLN2

2.67e-0644173519322198
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ABCA12 L1TD1 YTHDC2 ITGA3 CUL7 SRCAP TRIM66 PASK FAT1 TC2N BRCA1 LRP2 XYLB OSMR DHX34 GARRE1 ARAP2 KNL1 BRWD1

3.33e-0611161731931753913
Pubmed

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly.

LEFTY2 LEFTY1 LRP2

4.17e-067173332876567
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH9

4.17e-067173331178125
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TRIO KALRN SYNE1 GRIA1 RAB3C UBE2N PLCB1 PLCL1 HOMER2

5.10e-06251173927507650
Pubmed

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.

BRCA1 UBE2N UBE2W

6.65e-068173317873885
Pubmed

Broad mesodermal and endodermal deletion of Nodal at postgastrulation stages results solely in left/right axial defects.

LEFTY2 LEFTY1 DNAH5

6.65e-068173318773491
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRIO KALRN ACO1 SYNE1 SPTB LARS1 SEC31A PRPF8 TRIM66 SACS PKD1 LRP2 UTRN RAB5B TARBP1 RAB6A ARHGAP21 TARS1 ZNF292 BRWD1

6.87e-0612851732035914814
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPV1 TRPM2 TRPM1 MCOLN2

6.89e-0625173416382100
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

MRPS31 ZNF717 FLNA SYNE1 PRPF8 SLC3A2 PKD1 OSBPL9 DNAH9 MCOLN2

7.25e-063331731032665550
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FLNA PRR5L CENPN SEC31A RBM28 SRCAP MFAP3 VILL KCNH1 TET1 LRP2 OGDHL PRKCZ NFAT5 ATP2B1 UTRN ARHGAP21 BRWD1

8.59e-0610841731811544199
Pubmed

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.

LAMP1 LEFTY2 LEFTY1 LRP2

9.49e-0627173431308417
Pubmed

An introduction to TRP channels.

TRPV1 TRPM2 TRPM1 MCOLN2

9.49e-0627173416460286
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

GRIA1 CHRNB3 SLC3A2 ADGRL4 CUL5 TC2N TMEM87B PKD1 SHOC1 NCOA1 XYLB SCLT1 TARBP1 MCOLN2

9.56e-066861731429987050
Pubmed

Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.

RAB6B RAB3C RAB26 RAB5B RAB6A

1.06e-0558173511856727
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNA ABCA12 SYNE1 TNS2 CUL7 KCNH1 OSMR DNAH5

1.28e-05214173822199357
Pubmed

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.

RAB6B RAB3C RAB26 RAB5B RAB6A

1.36e-0561173512578829
Pubmed

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain.

RAB6B RAB3C RAB26 RAB5B RAB6A

1.48e-0562173511773082
Pubmed

Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination.

BRCA1 UBE2N UBE2W

1.94e-0511173319712108
Pubmed

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.

LEFTY2 LEFTY1 PKD1

1.94e-0511173327272319
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

MRPS31 FLNA UBE2NL CLTCL1 KRT31 KRT27 KRT33B LARS1 SRP72 YTHDC2 PRPF8 RAB6B RAB3C SLC3A2 UBE2N HSP90AB2P KRT25 RAB6A

1.96e-0511531731829845934
Pubmed

In with the TRP channels: intracellular functions for TRPM1 and TRPM2.

TRPM2 TRPM1

2.46e-052173219887679
Pubmed

A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells.

TRPV1 TRPM1

2.46e-052173219439586
Pubmed

A clinical and molecular genetic study of Egyptian and Saudi Arabian patients with primary congenital glaucoma (PCG).

CYP1B1 MYOC

2.46e-052173217224759
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

2.46e-052173211792814
Pubmed

Mutation spectrum of CYP1B1 and MYOC genes in Korean patients with primary congenital glaucoma.

CYP1B1 MYOC

2.46e-052173221850185
Pubmed

Molecular basis for involvement of CYP1B1 in MYOC upregulation and its potential implication in glaucoma pathogenesis.

CYP1B1 MYOC

2.46e-052173223028769
Pubmed

Rab6-Mediated Polarized Transport of Synaptic Vesicle Precursors Is Essential for the Establishment of Neuronal Polarity and Brain Formation.

RAB6B RAB6A

2.46e-052173238830762
Pubmed

LEFTY, a member of the transforming growth factor-beta superfamily, inhibits uterine stromal cell differentiation: a novel autocrine role.

LEFTY2 LEFTY1

2.46e-052173220056823
Pubmed

Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

LEFTY2 LEFTY1

2.46e-052173210053005
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-2 ERVV-1

2.46e-052173218826608
Pubmed

Myocilin gene implicated in primary congenital glaucoma.

CYP1B1 MYOC

2.46e-052173215733270
Pubmed

Mutation analysis of human LEFTY A and LEFTY B genes in children with Ivemark syndrome.

LEFTY2 LEFTY1

2.46e-052173211100524
Pubmed

Contributions of MYOC and CYP1B1 mutations to JOAG.

CYP1B1 MYOC

2.46e-052173218385784
Pubmed

Effect of hypoxia on the expression of iron regulatory proteins 1 and the mechanisms involved.

HIF1A ACO1

2.46e-052173221360641
Pubmed

[Two variants in MYOC and CYP1B1 genes in a Chinese family with primary angle-closure glaucoma].

CYP1B1 MYOC

2.46e-052173218841557
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

2.46e-052173226858404
Pubmed

Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.

ERVV-2 ERVV-1

2.46e-052173223555306
Pubmed

Genotype/phenotype correlation in primary congenital glaucoma patients from different ethnic groups of the Israeli population.

CYP1B1 MYOC

2.46e-052173221168818
Pubmed

Genotype/Phenotype Correlation in Primary Congenital Glaucoma Patients in the Lebanese Population: A Pilot Study.

CYP1B1 MYOC

2.46e-052173224940937
Pubmed

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes.

HIF1A TET1

2.46e-052173231935962
Pubmed

FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma.

HIF1A FAT1

2.46e-052173227536856
Pubmed

Screening of CYP1B1 and MYOC in Moroccan families with primary congenital glaucoma: three novel mutations in CYP1B1.

CYP1B1 MYOC

2.46e-052173220664688
Pubmed

14-3-3 proteins regulate cullin 7-mediated Eag1 degradation.

CUL7 KCNH1

2.46e-052173236717938
Pubmed

Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer.

HIF1A PRKCZ

2.46e-052173214744756
Pubmed

CYP1B1 and MYOC Mutations in Vietnamese Primary Congenital Glaucoma Patients.

CYP1B1 MYOC

2.46e-052173226550974
Pubmed

CYP1B1 mutations in French patients with early-onset primary open-angle glaucoma.

CYP1B1 MYOC

2.46e-052173215342693
Pubmed

Lefty1 Ameliorates Post-infarction Fibrosis by Suppressing p-Smad2 and p-ERK1/2 Signaling Pathways.

LEFTY2 LEFTY1

2.46e-052173233409963
Pubmed

CYP1B1 and MYOC variants in neonatal-onset versus infantile-onset primary congenital glaucoma.

CYP1B1 MYOC

2.46e-052173234526297
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

2.46e-052173224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

2.46e-052173224586179
Pubmed

Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.

LEFTY2 LEFTY1

2.46e-052173217038673
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

2.46e-052173217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

2.46e-052173231578382
Pubmed

Sequence analysis of MYOC and CYP1B1 in a Chinese pedigree of primary open-angle glaucoma.

CYP1B1 MYOC

2.46e-052173221655360
Pubmed

Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells.

YTHDC2 TET1

2.46e-052173237474847
Pubmed

Isolation, characterization, and function of EBAF/LEFTY B: role in infertility.

LEFTY2 LEFTY1

2.46e-052173221401636
Pubmed

FANCM regulates repair pathway choice at stalled replication forks.

FANCM BRCA1

2.46e-052173233882298
Pubmed

Occurrence of MYOC and CYP1B1 variants in juvenile open angle glaucoma Brazilian patients.

CYP1B1 MYOC

2.46e-052173230484747
Pubmed

LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway.

LEFTY2 LEFTY1

2.46e-052173232745796
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

2.46e-052173224931616
Pubmed

Sequence analysis of MYOC and CYP1B1 in a Chinese pedigree of juvenile glaucoma with goniodysgenesis.

CYP1B1 MYOC

2.46e-052173219668597
Pubmed

High frequency of HIF-1alpha overexpression in BRCA1 related breast cancer.

HIF1A BRCA1

2.46e-052173218030615
Pubmed

New perspectives in aqueous humor secretion and in glaucoma: the ciliary body as a multifunctional neuroendocrine gland.

CYP1B1 MYOC

2.46e-052173217321191
Pubmed

Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells.

RAB6C RAB6A

2.46e-052173211054569
Pubmed

CYP1B1 and MYOC mutations in 116 Chinese patients with primary congenital glaucoma.

CYP1B1 MYOC

2.46e-052173218852424
Pubmed

Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells.

LEFTY2 LEFTY1

2.46e-052173224147624
Pubmed

Hypoxia-induced TET1 facilitates trophoblast cell migration and invasion through HIF1α signaling pathway.

HIF1A TET1

2.46e-052173228808304
Pubmed

The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia.

HIF1A ACO1

2.46e-052173230415773
Pubmed

Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage.

TRPV1 TRPM2

2.46e-052173223458684
Pubmed

Differential expression of type I hair keratins.

KRT33A KRT33B

2.46e-05217321689759
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

2.46e-052173222768332
Pubmed

Lefty antagonises TGF-beta1 induced epithelial-mesenchymal transition in tubular epithelial cells.

LEFTY2 LEFTY1

2.46e-052173220171171
Pubmed

Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.

LEFTY2 LEFTY1

2.46e-05217329496783
Pubmed

A functional role of LEFTY during progesterone therapy for endometrial carcinoma.

LEFTY2 LEFTY1

2.46e-052173229268772
Pubmed

SLC3A2 and SLC7A2 Mediate the Exogenous Putrescine-Induced Adipocyte Differentiation.

SLC3A2 SLC7A2

2.46e-052173236572564
Pubmed

Screening of common CYP1B1 mutations in Iranian POAG patients using a microarray-based PrASE protocol.

CYP1B1 MYOC

2.46e-052173219096718
Pubmed

Melatonergic system-based two-gene index is prognostic in human gliomas.

CYP1B1 ASMT

2.46e-052173226510398
Pubmed

LEFTY2 inhibits endometrial receptivity by downregulating Orai1 expression and store-operated Ca2+ entry.

LEFTY2 LEFTY1

2.46e-052173229230527
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

2.46e-052173217267447
Pubmed

HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.

HIF1A NFAT5

2.46e-052173230982460
Pubmed

A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms.

KRT33A KRT33B

2.46e-05217327565656
Pubmed

Anti-inflammatory effects of Lefty-1 in renal tubulointerstitial inflammation via regulation of the NF-κB pathway.

LEFTY2 LEFTY1

2.46e-052173229286065
Pubmed

RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated.

HIF1A YTHDC2

2.46e-052173226996300
Pubmed

The inheritance of juvenile onset primary open angle glaucoma.

CYP1B1 MYOC

2.46e-052173227779752
Pubmed

Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility.

CFAP47 CFAP65

2.46e-052173233472045
InteractionKRT6C interactions

KRT31 KRT27 KRT33B KRT34 INPPL1 CUL7 KRT25

3.07e-06761667int:KRT6C
InteractionTRIO interactions

FLNA TRIO KALRN LAMP1 ADA2 RHEB BRCA1 ITSN2

3.36e-061091668int:TRIO
InteractionKRT5 interactions

KRT31 KRT27 KRT33B KRT34 INPPL1 CUL7 PRPF8 CUL5 FGD5 KRT25

4.69e-0619316610int:KRT5
InteractionKRT3 interactions

KRT31 KRT27 KRT33B KRT34 INPPL1 CUL5 KRT25

8.22e-06881667int:KRT3
InteractionKRT79 interactions

KRT31 KRT27 KRT33B KRT34 INPPL1 KRT25

8.96e-06591666int:KRT79
InteractionKRT85 interactions

KRT31 KRT27 KRT33B KRT34 PRPF8 KRT25

1.09e-05611666int:KRT85
InteractionKRT74 interactions

KRT31 KRT27 KRT33B KRT34 KRT25

1.26e-05371665int:KRT74
InteractionKRT6B interactions

KRT31 KRT27 KRT33B INPPL1 PRPF8 CUL5 FGD5 KRT25

1.39e-051321668int:KRT6B
InteractionKRT71 interactions

KRT31 KRT27 KRT33B KRT34 KRT25

2.67e-05431665int:KRT71
InteractionLAMP2 interactions

HIF1A OSTM1 EI24 LAMP1 SLC3A2 RHEB RRAGC ADGRL4 SLC7A2 SYNE2 OSBPL9 LRP2 PLCB1 PLEKHM3 ATP2B1 RAB6A

4.53e-0560916616int:LAMP2
InteractionRAB11B interactions

TRPV1 CUL7 USP5 UBE2N ABCC2 SCLT1 RAB5B RAB6A

5.06e-051581668int:RAB11B
InteractionRAB6C interactions

RAB6B RAB6C RAB6A

6.31e-05101663int:RAB6C
InteractionRAC1 interactions

CYP1B1 FLNA TRIO KALRN INPPL1 ITGA3 SLC3A2 RHEB SLC7A2 MFAP3 FAT1 MAP4K5 ARHGAP12 LRP2 FGD5 OSMR ATP2B1 UTRN GARRE1 HOMER2 ARHGAP21 ARAP2

6.35e-05106316622int:RAC1
InteractionKRT81 interactions

KRT31 KRT27 KRT33B KRT34 KRT25

7.44e-05531665int:KRT81
InteractionKRT78 interactions

KRT31 KRT27 KRT33B KRT34 KRT25 KNL1

8.30e-05871666int:KRT78
CytobandEnsembl 112 genes in cytogenetic band chr17q21

EME1 KRT31 KRT33A KRT27 KRT33B KRT34 ITGA3 BRCA1 KRT25

8.47e-054731739chr17q21
Cytoband17q21.2

KRT27 KRT33B KRT34 KRT25

1.47e-0470173417q21.2
GeneFamilyKeratins, type I

KRT31 KRT33A KRT27 KRT33B KRT34 KRT25

3.22e-08281256608
GeneFamilyDyneins, axonemal

DNAH3 DNAH17 DNAH5 DNAH6 DNAH9

8.44e-08171255536
GeneFamilyRAB, member RAS oncogene GTPases

RAB6B RAB3C RAB6C RAB26 RAB5B RAB6A

5.73e-06651256388
GeneFamilyTransient receptor potential cation channels

TRPV1 TRPM2 TRPM1 MCOLN2

3.92e-05281254249
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB ARHGAP12 OSBPL9 FGD5 PLEKHM3 PLEKHO1 ARHGAP21 ARAP2

9.33e-052061258682
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

2.82e-04412521252
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO KALRN ITSN2 FGD5

1.13e-03661254722
GeneFamilyCullins

CUL7 CUL5

1.29e-03812521032
GeneFamilyUbiquitin conjugating enzymes E2

UBE2NL UBE2N UBE2W

2.84e-03411253102
GeneFamilyATP binding cassette subfamily C

ABCC11 ABCC2

3.52e-03131252807
CoexpressionGABRIELY_MIR21_TARGETS

MGAT4A YTHDC2 RAB6C RRAGC PER3 SYNE2 TET1 ITSN2 SERAC1 NFAT5 UTRN ARHGAP21 KNL1 ZNF292

7.41e-0928917114M2196
CoexpressionPGF_UP.V1_DN

TRIO KRT31 SPTB GRIA1 SRCAP SVEP1 PKD1 DHX34 HOMER2

4.64e-061901719M2673
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

FLNA KRT31 KRT33A KRT27 KRT33B KRT34 LAD1 PIWIL2 MFAP3 TC2N RHOV PKD1 PLCB1 KRT25 RAB6A HOMER2

6.03e-0665017116MM1042
CoexpressionMARTINEZ_TP53_TARGETS_DN

FLNA KRT31 KRT33A KRT27 KRT33B KRT34 LAD1 PIWIL2 MFAP3 TC2N RHOV PKD1 PLCB1 KRT25 RAB6A HOMER2

7.17e-0665917116MM1040
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_DN

FLNA KRT31 KRT33A KRT27 KRT34 LAD1 PIWIL2 MFAP3 TC2N RHOV PKD1 PLCB1 KRT25 RAB6A HOMER2

1.21e-0561017115M3854
CoexpressionMARTINEZ_TP53_TARGETS_DN

FLNA KRT31 KRT33A KRT27 KRT34 LAD1 PIWIL2 MFAP3 TC2N RHOV PKD1 PLCB1 KRT25 RAB6A HOMER2

1.33e-0561517115M8673
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

GALNT14 HIF1A TRIO PLCB1 NCOA1 NFAT5 DNAH5 BRWD1

1.59e-051691718M39230
CoexpressionGSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP

MRPS31 CENPN OSTM1 ACO1 CRAT WDR91 XYLB KNL1

2.61e-051811718M6857
CoexpressionFEKIR_HEPARG_SIDE_POP_VS_HEPARG_UP

FLNA ITGA3 FAT1 SACS ABCC2 PLEKHO1

2.79e-05901716M48360
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

CUL7 SLC3A2 RRAGC PER3 RNF103 MAP4K5 NFIL3 ARHGAP12 ITSN2 PKD1 NCOA1 NFAT5 DHX34 ATP2B1 RAB6A GARRE1 BRWD1

2.90e-0582217117M6782
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

4.71e-0531717110M40298
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

HIF1A TRIO FAT1 BRCA1 SACS MAP4K5 ARHGAP12 SYNE2 ITSN2 NCOA1 OSMR ATP2B1 RAB6A GARRE1 ARAP2 ZNF292 CHST3

4.80e-0585617117M4500
CoexpressionBROWNE_HCMV_INFECTION_20HR_DN

TRIO KRT34 ACO1 SYNE1 ITGA3 ATP2B1

5.67e-051021716M5601
CoexpressionTANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA

KRT31 KRT33A KRT33B KRT34 SLC3A2 TARBP1

5.67e-051021716M14455
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

MRPS31 CFAP47 DNAH3 CFAP73 SYNE1 RGS22 HOATZ FABP6 AGBL4 DNAH5 DNAH6 DNAH9

1.53e-1119317312ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

1.18e-1017817311de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

1.78e-101851731118a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

1.99e-10187173119e10ed56090d82589bc457788282f664b70ace4b
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

1.99e-1018717311f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.23e-101891731127329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

MRPS31 CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 AGBL4 DNAH5 DNAH6 DNAH9

2.23e-10189173113e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

2.50e-101911731146c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

2.50e-1019117311995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

2.50e-1019117311a37f20172b85566b9039254a89680e37fd503fd5
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.50e-10191173111c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

2.50e-10191173112a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

2.50e-10191173112d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.50e-1019117311e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.50e-10191173119d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.64e-1019217311d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.64e-1019217311354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.64e-1019217311eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH3 CFAP73 SYNE1 RGS22 HOATZ AGBL4 SHOC1 DNAH5 DNAH6 DNAH9

2.95e-10194173114a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 AGBL4 DNAH5 DNAH6 DNAH9

2.95e-1019417311958e648138676d46698090b4046cb484083ae449
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH3 CFAP73 SYNE1 RGS22 CFAP65 AGBL4 SYNE2 DNAH5 DNAH6 DNAH9

3.48e-101971731174a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP47 DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

3.87e-10199173112de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFAP47 DNAH3 CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

4.08e-1020017311721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

4.08e-102001731185c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

4.08e-102001731112bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.49e-0918117310dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP47 DNAH3 CFAP73 RGS22 FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

2.63e-0918217310fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH6 DNAH9

3.08e-09185173103e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH6 DNAH9

3.60e-091881731034b11f72ca73153d02edcd09b38983ad1a504659
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH6 DNAH9

3.60e-091881731061a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH6 DNAH9

3.60e-09188173102b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

3.78e-0918917310a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH5 DNAH9

3.78e-0918917310c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH6 DNAH9

3.78e-091891731068a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 AGBL4 DNAH6 DNAH9

3.78e-0918917310b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.19e-09191173107b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.19e-0919117310fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH9

4.19e-0919117310ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.19e-0919117310c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.19e-0919117310cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP73 MUC15 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.19e-0919117310b4e335e798c9617356b8e24412f9270c42dce656
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH9

4.19e-09191173106228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 AGBL4 DNAH5 DNAH6 DNAH9

4.63e-09193173100e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.63e-0919317310aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 HOATZ CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

4.86e-091941731043be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

5.11e-091951731007a6bcef6af93ed87df455dee624037cb75e011a
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 RGS22 FABP6 AGBL4 SYNE2 DNAH5 DNAH6 DNAH9

5.11e-091951731021dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KALRN SYNE1 GRIA1 CSMD3 AGBL4 KCNH1 PKD1 PLCB1 ATP2B1 TARBP1

5.37e-0919617310676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH3 SYNE1 HOATZ AGBL4 SYNE2 OSMR DNAH5 DNAH6 DNAH9

5.37e-09196173106d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH3 SYNE1 HOATZ AGBL4 SYNE2 OSMR DNAH5 DNAH6 DNAH9

5.37e-0919617310af4cdc61830685a888a1209826c23bcf54a43084
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP47 DNAH3 CFAP73 SYNE1 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

6.51e-09200173106a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

KALRN SYNE1 GRIA1 CSMD3 AGBL4 KCNH1 PKD1 PLCB1 ATP2B1 TARBP1

6.51e-092001731048d801219bc771d6c7e151dc88ca4c179988de85
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

MRPS31 CFAP47 DNAH3 CFAP73 RGS22 HOATZ CFAP65 DNAH5 DNAH6 DNAH9

6.51e-0920017310bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

6.51e-09200173109ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH9

2.83e-081741739b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH9

2.83e-08174173900cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH9

2.97e-081751739b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCellPCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH9

2.97e-081751739c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

3.97e-0818117395a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

3.97e-081811739a4e891603645f694687e68e585744ddc1a3c8697
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 FABP6 CFAP65 AGBL4 DNAH6 DNAH9

4.17e-0818217397ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

4.37e-081831739cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

4.37e-081831739b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 KALRN ABCA12 RGS22 CSMD3 FAT1 LRP2 DNAH5 DNAH9

4.58e-0818417392cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 KALRN ABCA12 RGS22 CSMD3 FAT1 LRP2 DNAH5 DNAH9

4.58e-0818417392b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH6 DNAH9

4.58e-0818417395daff849625f2f41d56615569c0ed59cd733b34c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRP2 KALRN ABCA12 RGS22 CSMD3 FAT1 LRP2 DNAH5 DNAH9

4.58e-081841739ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

DNAH3 CFAP73 MUC15 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

4.79e-0818517390998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH3 CFAP73 RGS22 FABP6 CFAP65 AGBL4 DNAH6 DNAH9

4.79e-08185173930f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH3 CFAP73 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

5.26e-081871739e61992de4f98eeea08b43213850769d923f8db48
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

CFAP73 RGS22 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

5.51e-081881739803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

6.31e-0819117399f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

6.31e-0819117395129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

6.31e-081911739df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

6.31e-081911739b78547dae8328244a47c83346447bdd787efbcae
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP73 MUC15 HOATZ FABP6 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

6.31e-081911739c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

6.59e-081921739097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 CFAP73 SYNE1 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

6.59e-081921739be592e661367affced9ebe80849b466e6adb3a34
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 CFAP73 MUC15 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

6.59e-0819217396c269d2426f76559d2ed3bf2169eb4be5fc7ad6d
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 CFAP73 SYNE1 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

6.89e-0819317390b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MRPS31 CFAP73 SYNE1 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.21e-081941739b4ce60c06568123008b1081d644733cb91c28f51
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DNAH3 CFAP73 RGS22 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

7.21e-0819417391ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MRPS31 CFAP73 SYNE1 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.21e-0819417397a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.21e-081941739b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 SYNE1 AGBL4 SYNE2 DNAH5 DNAH6 DNAH9

7.53e-081951739fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH3 CFAP73 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.53e-081951739cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-08195173993b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DNAH3 CFAP73 SYNE1 AGBL4 SYNE2 DNAH5 DNAH6 DNAH9

7.53e-081951739eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.53e-081951739d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 MUC15 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-081951739649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-0819517390e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 RGS22 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-081951739581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 MUC15 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-081951739129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 DNAH3 CFAP73 MUC15 HOATZ FABP6 DNAH5 DNAH6 DNAH9

7.53e-0819517393e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.53e-081951739e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 CFAP73 MUC15 RGS22 CFAP65 SLC7A2 DNAH5 DNAH6 DNAH9

7.87e-08196173927b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.87e-081961739a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRPS31 CFAP73 RGS22 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.87e-081961739009e83c7251cf300be78b263634d233a8d972a68
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CFAP47 DNAH3 CFAP73 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.87e-0819617391cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP47 DNAH3 CFAP73 HOATZ FABP6 CFAP65 DNAH5 DNAH6 DNAH9

7.87e-08196173969f5081e06d84ec1d9695762df801a9d0df1984b
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO GRIA1 ATP2B1 ZNF292

2.12e-06171654DOID:0060307 (is_implicated_in)
DiseaseColorectal Carcinoma

CYP1B1 DNAH3 ZNF560 KALRN ABCA12 SYNE1 CSMD3 RHEB FAT1 SACS TOMM40L CD226 LRP2 PRKCZ ABCC2 ZNF292

2.27e-0670216516C0009402
DiseaseGLAUCOMA 3, PRIMARY CONGENITAL, A

CYP1B1 MYOC

3.11e-0521652C1856439
DiseaseGlaucoma of childhood

CYP1B1 MYOC

3.11e-0521652C2981140
DiseaseGLAUCOMA 1, OPEN ANGLE, A

CYP1B1 MYOC

3.11e-0521652C1842028
Diseaseretinal degeneration (implicated_via_orthology)

RAB6D RAB6B RAB6C RAB6A

3.40e-05331654DOID:8466 (implicated_via_orthology)
DiseaseSitus ambiguus

LEFTY2 DNAH5 DNAH9

7.44e-05151653C0266642
DiseaseBipolar Disorder

HIF1A SYNE1 TRPM2 GRIA1 CHRNB3 TAAR6 PER3 ASMT PLCB1 PRKCZ PLEKHO1

8.29e-0547716511C0005586
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.85e-0441652cv:CN293514
DiseaseMammary Carcinoma, Human

CYP1B1 FLNA HIF1A SYNE1 CUL5 PER3 BRCA1 KCNH1 ITSN2 NCOA1 FGD5

1.91e-0452516511C4704874
DiseaseMammary Neoplasms, Human

CYP1B1 FLNA HIF1A SYNE1 CUL5 PER3 BRCA1 KCNH1 ITSN2 NCOA1 FGD5

1.91e-0452516511C1257931
DiseaseMammary Neoplasms

CYP1B1 FLNA HIF1A SYNE1 CUL5 PER3 BRCA1 KCNH1 ITSN2 NCOA1 FGD5

1.98e-0452716511C1458155
DiseaseIntellectual Disability

TRIO SYNE1 GRIA1 RBM28 BRCA1 SACS LRP2 SERAC1 ZMYM6 ZNF292

2.23e-0444716510C3714756
DiseaseBreast Carcinoma

CYP1B1 FLNA HIF1A SYNE1 CUL5 PER3 BRCA1 KCNH1 ITSN2 NCOA1 FGD5

2.36e-0453816511C0678222
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

3.07e-0451652C1450051
DiseaseHydrophthalmos

CYP1B1 MYOC

3.07e-0451652C0020302
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

3.07e-0451652C0410190
Diseasecerebellum growth measurement

TAAR6 DNAH9

3.07e-0451652EFO_0009327
Diseaseresponse to bevacizumab, Proteinuria

TRIO DNAH5

3.07e-0451652EFO_0005943, HP_0000093
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

4.59e-0461652cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

4.59e-0461652C0410189
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

4.59e-0461652EFO_0021525
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

ABCA12 BSX MAP4K5 ATP2B1

6.14e-04691654EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

6.41e-0471652C0751337
Diseasepuberty onset measurement

TRPM2 MAP4K5 PLCL1 NFAT5 BRWD1

7.03e-041251655EFO_0005677
Diseasechemotherapy-induced alopecia, methylcobalamin deficiency type cblE

TRIO DNAH5

8.51e-0481652EFO_0005400, MONDO_0009354
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

8.51e-0481652EFO_0010913
Diseasesialic acid-binding Ig-like lectin 12 measurement

KALRN MAP4K5

8.51e-0481652EFO_0802066
Diseasepsoriasis

OSTM1 ACO1 SPATA31C2 SPATA31C1 SYNE2 GRHL3 IL23R

9.02e-042731657EFO_0000676
DiseaseDisproportionate short stature

FLNA CUL7 WDR35 CHST3

9.29e-04771654C0878659
DiseaseColorectal Neoplasms

CYP1B1 ABCA12 SYNE1 FAT1 CD226 ABCC2 ZNF292

9.82e-042771657C0009404
DiseaseMalignant neoplasm of breast

CYP1B1 FLNA HIF1A KALRN SYNE1 CUL5 PER3 BRCA1 KCNH1 SYNE2 ITSN2 PLCB1 NCOA1 FGD5 DNAH9

1.07e-03107416515C0006142
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 40

BRCA1 DHX34

1.09e-0391652C4225275
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

1.09e-0391652EFO_0007645
DiseaseSitus ambiguous

LEFTY2 DNAH9

1.09e-0391652C1167664
Diseaselung non-small cell carcinoma (is_implicated_in)

HIF1A SLC3A2 FAT1 BRCA1 ABCC2

1.13e-031391655DOID:3908 (is_implicated_in)
Diseasebeverage consumption measurement

ITSN2 NCOA1 PLCL1 SCLT1

1.23e-03831654EFO_0010088
Diseasealanine measurement

CLTCL1 SLC7A2 KCNH1 MAP4K5

1.40e-03861654EFO_0009765
Diseasewaist-hip ratio

PRR5L YTHDC2 CFAP65 MEP1A AGBL4 TRIM66 SLC7A2 DNAH17 SYNE2 PKD1 WDR35 HSP90AB2P NFAT5 RAB26 ARHGAP21 KNL1

1.47e-03122616516EFO_0004343
Diseaselevel of Ceramide (d40:1) in blood serum

MAP4K5 SYNE2

1.65e-03111652OBA_2045185
DiseaseNeurodevelopmental Disorders

TRIO SRCAP KCNH1 ZNF292

1.87e-03931654C1535926
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.98e-03121652DOID:11726 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

TRIO KALRN ITGA3 RAB3C KCNH1

2.28e-031631655DOID:1826 (implicated_via_orthology)
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

2.33e-03131652EFO_0005939, EFO_0007018
Diseasereticulocyte measurement

FLNA SPTB PRPF8 CUL5 FAT1 CD226 MAP4K5 NFIL3 DNAH17 SYNE2 PLCB1 OSMR ATP2B1 ARHGAP21

2.46e-03105316514EFO_0010700
Diseaseretinal vasculature measurement

TRIO PIWIL2 NFIL3 PLCB1 PLCL1 OSMR DNAH5 DNAH9 KNL1

2.62e-035171659EFO_0010554
Diseasediffuse large B-cell lymphoma

ITSN2 NCOA1

2.71e-03141652EFO_0000403
Diseasehepatic encephalopathy (biomarker_via_orthology)

HIF1A GRIA1

3.11e-03151652DOID:13413 (biomarker_via_orthology)
DiseaseMental Depression

HIF1A GRIA1 CHRNB3 PER3 BRCA1 ASMT

3.14e-032541656C0011570
Diseasebody surface area

LRRC66 SPATA31C2 GRIA1 SPATA31C1 AGBL4 TRIM66 MFAP3 MAP4K5 NFIL3 ITSN2

3.45e-0364316510EFO_0022196
DiseaseSpondyloepiphyseal Dysplasia

FLNA CHST3

3.54e-03161652C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLNA CHST3

3.54e-03161652C3541456
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

3.54e-03161652EFO_0021490
DiseaseSchwartz-Jampel Syndrome, Type 1

FLNA CHST3

3.54e-03161652C4551479
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA1 SEC31A

3.54e-03161652DOID:331 (implicated_via_orthology)
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKD1 SCLT1

3.54e-03161652DOID:0110861 (implicated_via_orthology)
DiseaseSchwartz-Jampel Syndrome

FLNA CHST3

3.54e-03161652C0036391
DiseaseMelnick-Needles Syndrome

FLNA CHST3

3.54e-03161652C0025237
DiseaseAutistic Disorder

GRIA1 CUL7 CSMD3 PASK ASMT ZNF292

3.59e-032611656C0004352
DiseaseNasal Cavity Polyp

ITSN2 NCOA1 RAB5B

3.64e-03551653EFO_1000391
Diseasegrip strength measurement

GRIA1 MFAP3 PKD1 NCOA1 PLCL1 NFAT5 RAB6A

3.66e-033501657EFO_0006941
DiseaseVan Buchem disease

FLNA CHST3

4.00e-03171652C0432272
Diseasevital capacity

SYNE1 PCDHA12 PIWIL2 SVEP1 ADGRL4 TRIM66 LRP2 PLCB1 NCOA1 PLCL1 XYLB HSP90AB2P NFAT5 UTRN HOMER2

4.08e-03123616515EFO_0004312
Diseaseneuroblastoma

TRIO KALRN L1TD1 DNAH5

4.15e-031161654EFO_0000621
Diseasehematocrit

KALRN ACO1 ADGRL4 FABP6 FAT1 KCNH1 MAP4K5 LRP2 PLCB1 FGD5 OSMR NFAT5 ARHGAP21

4.61e-03101116513EFO_0004348
DiseaseSjogren syndrome

ITSN2 NCOA1 NFAT5

4.65e-03601653EFO_0000699
Diseaseamino acid measurement

PRR5L CLTCL1 ABCA12 SYNE1 PASK SLC7A2 PER3 MAP4K5 LRP2 MCOLN2

4.99e-0367816510EFO_0005134
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA CHST3

4.99e-03191652DOID:2256 (is_implicated_in)
DiseaseOsteochondrodysplasias

FLNA CHST3

4.99e-03191652C0029422
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

4.99e-03191652DOID:10003 (implicated_via_orthology)
DiseaseDyschondroplasias

FLNA CHST3

4.99e-03191652C0013366
Diseasephosphatidylcholine measurement

AGBL4 MAP4K5 SYNE2 PLCB1 NCOA1 ZMYM6

5.40e-032841656EFO_0010226
DiseaseMultiple Epiphyseal Dysplasia

FLNA CHST3

5.53e-03201652C0026760
Diseaseselenium measurement, response to dietary selenium supplementation

TRIO DNAH5

5.53e-03201652EFO_0006331, EFO_0600021

Protein segments in the cluster

PeptideGeneStartEntry
AEQWKTNEAQAIETA

UBE2N

126

P61088
VVEQWKTNEAQAIET

UBE2NL

126

Q5JXB2
EVYQKIETVNESWNA

ACO1

611

P21399
KTVNNFVQRDTFVVW

ADGRL4

196

Q9HBW9
FISQVVQDWKFVAQV

CHRNB3

411

Q05901
FVKNSNNALAWEKTT

EGFL6

481

Q8IUX8
RQESVTKQQWFDLFS

CUL5

31

Q93034
NAQCVWVITAVNTNK

CSMD3

571

Q7Z407
SIEQVLNDFSQWKQI

ADAM21

271

Q9UKJ8
SFFSQVQEQKAVWQL

ABCA12

251

Q86UK0
ALSLSETQVKTWFQN

BSX

146

Q3C1V8
HSKAQVDAWQQIQTF

ACOT6

391

Q3I5F7
ADQIFVQLEKIWNSS

CRAT

226

P43155
AQWNENSLVSFSKII

ERVV-2

21

B6SEH9
ATSTEKSVAWQNSNE

ARAP2

311

Q8WZ64
NSFITKWKDTQVSQA

ARAP2

1311

Q8WZ64
WTAKQHFSFQEEEQI

ASMT

216

P46597
VFQQTESEEKTNRTW

ADCY10

751

Q96PN6
ESKWIQIQNTAAEKT

CFAP73

231

A6NFT4
ESAWVNKVFTAVNIL

SLC7A2

186

P52569
VVLVTAFNDWSKEKQ

ATP2B1

166

P20020
VTNKASFDNIQAWLT

RAB26

146

Q9ULW5
SWTGFQTKAEVEQVE

RBM28

646

Q9NW13
FENVNATNAIMTWKV

OSMR

341

Q99650
ESFNAVQDWSTQIKT

RAB3C

116

Q96E17
DITNQETFARAKTWV

RAB5B

101

P61020
TNVNSFQQTTKWIDD

RAB6A

96

P20340
TNLNSFQQTSKWIDD

RAB6B

96

Q9NRW1
TNVNSFQQTTKWIDD

RAB6C

96

Q9H0N0
TNVNSFQQTTKWIDD

RAB6D

96

Q53S08
NVSFSNLTVNTSWQK

ITSN2

861

Q9NZM3
WVSKNSVTFVAEQVS

OSBPL9

486

Q96SU4
AQWTFESAVQENISI

NSL1

76

Q96IY1
QFAVETIQNEWKVYV

FAT1

2966

Q14517
NTIKNFALQLSSEEW

MGAT4A

271

Q9UM21
AQEVDVNSFSWNLKE

PASK

731

Q96RG2
QEAQKASSATERTQW

LAD1

491

O00515
KAFDVTEAVNFWQQL

LEFTY1

176

O75610
WFTTQTEELNKQVVS

KRT31

246

Q15323
SENFTWSLVNDTVKT

MUC15

146

Q8N387
SKEQVANSAFVEQVW

HSP90AB2P

266

Q58FF8
WVETQATVIYNTKNS

HIF1A

316

Q16665
FLNNISKNEEIAFSW

CFAP65

1461

Q6ZU64
LQESAASVEQWKRQF

HOMER2

201

Q9NSB8
VVIEHFKSWNAENTT

FANCM

456

Q8IYD8
AQWNENSLVSFSKII

ERVV-1

21

B6SEH8
AKVYNWIQSQTVTQE

PER3

1156

P56645
NVTVKARVWNSTFIE

ITGA3

926

P26006
VAAEWRNTFNKDVVV

OGDHL

476

Q9ULD0
FSVQVTNIQDWSLKS

NFIL3

381

Q16649
VEKQVNNFLTSSWRD

CUL7

1151

Q14999
RLSNWESQQKVADVF

FGD5

966

Q6ZNL6
QISTQLDQEWKSFAA

KALRN

391

O60229
SKALVFEEATLSWQQ

ABCC11

471

Q96J66
TWETNIRKQSVANAF

MYOC

416

Q99972
FKTRQNNVAWLVVDS

KCNH1

241

O95259
EAWFNEKSASLQQQI

KRT27

276

Q7Z3Y8
EAWFNEKSASLQQQI

KRT25

271

Q7Z3Z0
WFATQTEELNKQVVS

KRT33A

246

O76009
DKQITNRNTVSWEQS

KNL1

706

Q8NG31
NEVRIDTNQKCVFSW

ABCC2

1186

Q92887
QRVFWTDTVQNKVFS

LRP2

436

P98164
VILSEFFNTTWQEAN

OSTM1

156

Q86WC4
LTVQNNWKAFTFVLS

PLEKHM3

371

Q6ZWE6
AISSAQLQDFDWQVK

COMMD8

111

Q9NX08
YFNLETVQVTWNASK

CRLF2

36

Q9HC73
VIFQENVSDENSWKS

NFAT5

476

O94916
SVAVFQNFISESWRK

LRRC66

261

Q68CR7
KWLVSDNFLNITNVA

MFAP3

101

P55082
QSDNDTVINDWFKVL

ARHGAP12

556

Q8IWW6
WFKVLSSTINNQAVE

ARHGAP12

566

Q8IWW6
SAWNSVQTAVINVFK

PRR5L

51

Q6MZQ0
DAKSQVWAFTYTQQI

GALNT14

456

Q96FL9
WNAAFLESSAKENQT

RHEB

141

Q15382
NSSIQKVNEWFSRSD

BRCA1

376

P38398
VQSKVETVESFDWQR

DNAH6

1396

Q9C0G6
NALSFVWNVNEEAKV

GRHL3

336

Q8TE85
VKFNLAEFQEVWQQS

DSCC1

281

Q9BVC3
QQKLSTADSVISIWF

DNAH17

1476

Q9UFH2
IVAKVESSQAFTWQA

DNAH17

1771

Q9UFH2
SIFWTQEVSQALAEN

DNAH3

1291

Q8TD57
KVTANNDKNRTFSVW

FLNA

331

P21333
VLSKVVNAIWFQDIA

EI24

136

O14681
KIVTEVQQDGQDFTW

FABP6

36

P51161
TTVEDVNQDNKTKTW

GARRE1

961

O15063
KAVQKSTSENQTEWN

CENPJ

676

Q9HC77
TNQTWNVKEFDTNFT

IL23R

261

Q5VWK5
VWFNFTVENVKESQR

AGBL4

81

Q5VU57
NSWFSTQVDTVATKV

SLC3A2

316

P08195
IYTNQNVVWSKFETI

ADA2

196

Q9NZK5
KAWDFLSENQLQTVN

CENPN

26

Q96H22
VVTAVNDHVLKVWNS

BRWD1

441

Q9NSI6
EARQKQTFITWTQKN

DUXB

101

A0A1W2PPF3
KAFDVTEAVNFWQQL

LEFTY2

176

O00292
VTKAFSVNIFKVWVQ

LAMP1

346

P11279
SVNIFKVWVQAFKVE

LAMP1

351

P11279
KDTVVFVNQWSVNHD

CYP1B1

416

Q16678
AQAQIVQSWKELADF

EME1

421

Q96AY2
AIESAVIKWSYQVQV

DNAH9

216

Q9NYC9
GTWQKVIQVVQSDSF

CD226

116

Q15762
VLDTAAEKNWQVTAV

GRIA1

161

P42261
FNVFNAWVQVKSERS

DHX34

646

Q14147
VEFIFVNVENWDNKS

RNF103

261

O00237
NVTVDVFVQWFQDLK

SLC19A3

256

Q9BZV2
ANTENWSKETLQNTV

SACS

3611

Q9NZJ4
QTNDKWTFQVTIEGE

CFAP47

2341

Q6ZTR5
FATFAQIQQKSILVW

MCOLN2

466

Q8IZK6
NLSRFVWKQATVASE

DRP2

196

Q13474
ERWTEQSQEFAAQTK

DNAH5

3501

Q8TE73
VVQFETINLNSASSW

MAP4K5

701

Q9Y4K4
RWTINDKQSLTFQNV

PKD1

966

P98161
TVSAWDADAQKNALV

PCDHA12

476

Q9UN75
QDAESQKFRWVSESQ

MRC1

51

P22897
SLWDVEFAKQLATVN

MRPS31

276

Q92665
NTVIAKVNNVVWDLD

TARS1

116

P26639
NVLEKVSSEWKNVSQ

UTRN

771

P46939
AFKTWRQQDSEQAVI

SERAC1

406

Q96JX3
KDDISNSSFVNFQIW

RRAGC

101

Q9HB90
VFVNNLSTVCEKVWT

TMEM26

131

Q6ZUK4
ETTKTWCVFNSSVQQ

SPATA31C2

291

B4DYI2
QTVVNQNWVLTDFLS

TAAR6

191

Q96RI8
STQVEKFINDITTWF

SYNE1

2306

Q8NF91
QNRETFWAEQVTEVK

SYNE2

4806

Q8WXH0
SNNIEAVNQWKETVI

TC2N

461

Q8N9U0
VVKVVDNWAFGQQTV

FER1L5

1311

A0AVI2
EQWFATQTEELNKQV

KRT34

286

O76011
DWFALAKQSQQTVST

RGS22

206

Q8NE09
KNTSFITSQELNWVK

PIWIL2

576

Q8TC59
QQKWDTERVFEVNAS

LARS1

21

Q9P2J5
WTNNTVTAINQSKSE

NCOA1

891

Q15788
EQDANLAKQFWISAS

HOATZ

31

Q6PI97
WTVRNFSQVLENTSK

MEP1A

436

Q16819
QSSDNINFLKVQWSS

INPPL1

786

O15357
TANWKFATVIFDQTR

SHOC1

616

Q5VXU9
NWKEQSAVVLATVDN

RGN

81

Q15493
NIWNDAKTVNVITTA

SDAD1

191

Q9NVU7
QETTKTWCIFNSSVQ

SPATA31C1

296

P0DKV0
LSAVVAAQSNWEKVV

SRP72

151

O76094
DVRQFWSNVEKVVQF

SRCAP

201

Q6ZRS2
SDVAWTIQLTQDFKQ

MROH2B

586

Q7Z745
KTLEQQDSANVTWQI

SVEP1

576

Q4LDE5
EASSNWSQAKRVLQE

PLEKHO1

361

Q53GL0
QETTQFWSQRVEDSK

TET1

186

Q8NFU7
VQSASRSNNWEDLVK

CLTCL1

1141

P53675
STQKNSSEQFEKWRF

CHST3

416

Q7LGC8
LFSNQIIWFVDDTNV

PRPF8

1771

Q6P2Q9
NKATESFAWNITVLK

PLCL1

1021

Q15111
SVVQPSSFQNITEKW

RHOV

111

Q96L33
KFLLQNSWQTADISA

TRPV1

266

Q8NER1
LVSIVNVVWTFANNS

TAS2R9

81

Q9NYW1
TFQQVQEHTDQIWKF

TRPM2

1051

O94759
LGWDFSTQQVKVVAV

XYLB

11

O75191
LSDKQWEQFQTLVQV

ZNF292

121

O60281
TNDVFKEINTQILFW

TEX30

201

Q5JUR7
NQEKTQAVELWQTVS

SCLT1

141

Q96NL6
DDFQAWLSITQKAVA

SPTB

1071

P11277
VAKEWTNEVFSLATN

PLCB1

126

Q9NQ66
VSATEVELSWNSFNK

VILL

146

O15195
NNTFFEVKSISNQVW

TRPM1

1076

Q7Z4N2
FFWQIVITNSNTSTQ

ZNF717

111

Q9BY31
FIVSIKTENTDASWN

TMEM87B

181

Q96K49
VNTNSENWAVVKAAL

YTHDC2

961

Q9H6S0
ALFKSVSVTQFWINA

ZMYM6

1246

O95789
AKAVFQTQQAKFLTW

TOMM40L

121

Q969M1
NEKSVQNSITQWIVD

UBE2W

26

Q96B02
SNTQLIFWANLKAFV

TARBP1

981

Q13395
QTEFEKNVWSFLKVN

SEC31A

466

O94979
VVTWNEQYQKLTTSD

WDR35

76

Q9P2L0
VQNFINWAVCSKTSV

TRIM66

201

O15016
TEISVLNFWKVHEQS

ARHGAP21

1811

Q5T5U3
FFAKQATELQNQAEW

WDR91

111

A4D1P6
QVDDFWSTALQAKSV

USP5

541

P45974
SQSNVKFVQDTSKFW

TNS2

1126

Q63HR2
QIASQLEQEWKAFAA

TRIO

421

O75962
QTSVSALQQEFWKIQ

ZNF560

86

Q96MR9
WFATQTEELNKQVVS

KRT33B

246

Q14525
WVQTEKHVFEQASSN

PRKCZ

296

Q05513
SATLDISKQWSNVFN

L1TD1

251

Q5T7N2