Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR3	2.58e-05	4	42	2	GO:0005219
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR3	6.44e-05	6	42	2	GO:0048763
GeneOntologyMolecularFunction	phosphatidylcholine transfer activity	SCP2 ABCA3	6.44e-05	6	42	2	GO:0120019
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNG4 ITGAV RYR1	1.23e-04	46	42	3	GO:0005245
GeneOntologyMolecularFunction	calcium channel activity	CACNG4 ITGAV RYR1 RYR3	1.54e-04	129	42	4	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNG4 ITGAV RYR1 RYR3	2.81e-04	151	42	4	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNQ3 CACNG4 ITGAV RYR1	2.88e-04	152	42	4	GO:0022843
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNQ3 CACNG4 ITGAV RYR1	5.70e-04	182	42	4	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNQ3 CACNG4 ITGAV RYR1	5.94e-04	184	42	4	GO:0022832
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR3	6.47e-04	18	42	2	GO:0015278
GeneOntologyMolecularFunction	gated channel activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	6.50e-04	334	42	5	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	7.33e-04	343	42	5	GO:0005261
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	SCP2 ABCA3	8.01e-04	20	42	2	GO:0008525
GeneOntologyMolecularFunction	phospholipid transfer activity	SCP2 ABCA3	1.36e-03	26	42	2	GO:0120014
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	RYR1 RYR3	1.93e-03	31	42	2	GO:0099604
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR1 RYR3	2.19e-03	33	42	2	GO:0005217
GeneOntologyMolecularFunction	monoatomic ion channel activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	2.65e-03	459	42	5	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	2.80e-03	465	42	5	GO:0046873
GeneOntologyMolecularFunction	demethylase activity	ALKBH5 KDM5C	3.86e-03	44	42	2	GO:0032451
GeneOntologyMolecularFunction	calcium ion binding	AIF1 PCDHA11 MYOF CDH9 RYR1 RYR3	4.53e-03	749	42	6	GO:0005509
GeneOntologyMolecularFunction	channel activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	4.70e-03	525	42	5	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNQ3 CACNG4 ITGAV RYR1 RYR3	4.74e-03	526	42	5	GO:0022803
GeneOntologyBiologicalProcess	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	ANK2 RYR1 RYR3	6.24e-05	37	43	3	GO:0014808
GeneOntologyBiologicalProcess	release of sequestered calcium ion into cytosol by endoplasmic reticulum	ANK2 RYR1 RYR3	7.32e-05	39	43	3	GO:1903514
GeneOntologyBiologicalProcess	positive regulation of sterol transport	SCP2 ABCA3 ZDHHC8	7.90e-05	40	43	3	GO:0032373
GeneOntologyBiologicalProcess	positive regulation of cholesterol transport	SCP2 ABCA3 ZDHHC8	7.90e-05	40	43	3	GO:0032376
GeneOntologyBiologicalProcess	parallel actin filament bundle assembly	AIF1 FMN2	8.86e-05	7	43	2	GO:0030046
GeneOntologyBiologicalProcess	intracellular calcium ion homeostasis	NPY1R CAV2 ANK2 ITGAV RYR1 RYR3	9.44e-05	359	43	6	GO:0006874
GeneOntologyBiologicalProcess	sarcoplasmic reticulum calcium ion transport	ANK2 RYR1 RYR3	1.05e-04	44	43	3	GO:0070296
GeneOntologyBiologicalProcess	muscle system process	ADK AIF1 MYOF NPY1R ANK2 RYR1 RYR3	1.25e-04	547	43	7	GO:0003012
GeneOntologyBiologicalProcess	calcium ion homeostasis	NPY1R CAV2 ANK2 ITGAV RYR1 RYR3	1.46e-04	389	43	6	GO:0055074
GeneOntologyBiologicalProcess	T-tubule organization	MYOF ANK2	1.51e-04	9	43	2	GO:0033292
GeneOntologyBiologicalProcess	muscle cell development	MYOF PBRM1 CAV2 ANK2 RYR1	1.96e-04	259	43	5	GO:0055001
GeneOntologyBiologicalProcess	cellular response to caffeine	RYR1 RYR3	2.31e-04	11	43	2	GO:0071313
GeneOntologyBiologicalProcess	release of sequestered calcium ion into cytosol	ANK2 ITGAV RYR1 RYR3	2.40e-04	146	43	4	GO:0051209
GeneOntologyBiologicalProcess	negative regulation of sequestering of calcium ion	ANK2 ITGAV RYR1 RYR3	2.46e-04	147	43	4	GO:0051283
GeneOntologyBiologicalProcess	regulation of sequestering of calcium ion	ANK2 ITGAV RYR1 RYR3	2.59e-04	149	43	4	GO:0051282
GeneOntologyBiologicalProcess	sequestering of calcium ion	ANK2 ITGAV RYR1 RYR3	2.87e-04	153	43	4	GO:0051208
GeneOntologyBiologicalProcess	cell-cell adhesion	ADK AIF1 KIFAP3 PCDHA11 MIA3 PBRM1 ITGAV CDH9 HSPH1	3.15e-04	1077	43	9	GO:0098609
GeneOntologyBiologicalProcess	cellular response to purine-containing compound	RYR1 RYR3	3.80e-04	14	43	2	GO:0071415
GeneOntologyBiologicalProcess	regulation of lipid transport	SCP2 ABCA3 ITGAV ZDHHC8	5.20e-04	179	43	4	GO:0032368
GeneOntologyCellularComponent	sarcolemma	CACNG4 CAV2 ANK2 RYR1 RYR3	4.79e-05	190	44	5	GO:0042383
GeneOntologyCellularComponent	junctional membrane complex	RYR1 RYR3	1.54e-04	9	44	2	GO:0030314
GeneOntologyCellularComponent	calcium channel complex	CACNG4 RYR1 RYR3	4.88e-04	73	44	3	GO:0034704
GeneOntologyCellularComponent	T-tubule	CACNG4 ANK2 RYR1	6.15e-04	79	44	3	GO:0030315
GeneOntologyCellularComponent	perinuclear region of cytoplasm	AIF1 FMN2 SYNRG CAV2 ANK2 ZDHHC8 RYR1 RYR3	6.52e-04	934	44	8	GO:0048471
Domain	Ryanrecept_TM4-6	RYR1 RYR3	1.55e-05	3	43	2	IPR009460
Domain	RyR	RYR1 RYR3	1.55e-05	3	43	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR3	1.55e-05	3	43	2	IPR003032
Domain	RR_TM4-6	RYR1 RYR3	1.55e-05	3	43	2	PF06459
Domain	Ryan_recept	RYR1 RYR3	1.55e-05	3	43	2	IPR013333
Domain	RIH_assoc	RYR1 RYR3	7.72e-05	6	43	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR3	7.72e-05	6	43	2	IPR013662
Domain	RIH_dom	RYR1 RYR3	7.72e-05	6	43	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR3	7.72e-05	6	43	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR3	7.72e-05	6	43	2	IPR015925
Domain	-	RYR1 RYR3	7.72e-05	6	43	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR3	7.72e-05	6	43	2	PF01365
Domain	Ins145_P3_rec	RYR1 RYR3	7.72e-05	6	43	2	PF08709
Domain	MIR	RYR1 RYR3	2.30e-04	10	43	2	PS50919
Domain	MIR	RYR1 RYR3	2.30e-04	10	43	2	PF02815
Domain	MIR	RYR1 RYR3	2.30e-04	10	43	2	SM00472
Domain	MIR_motif	RYR1 RYR3	2.30e-04	10	43	2	IPR016093
Domain	BAH	MTA2 PBRM1	2.81e-04	11	43	2	SM00439
Domain	BAH	MTA2 PBRM1	2.81e-04	11	43	2	PF01426
Domain	BAH	MTA2 PBRM1	2.81e-04	11	43	2	PS51038
Domain	BAH_dom	MTA2 PBRM1	2.81e-04	11	43	2	IPR001025
Domain	-	ARID3C KDM5C	5.33e-04	15	43	2	1.10.150.60
Domain	BRIGHT	ARID3C KDM5C	5.33e-04	15	43	2	SM00501
Domain	ARID_dom	ARID3C KDM5C	5.33e-04	15	43	2	IPR001606
Domain	ARID	ARID3C KDM5C	5.33e-04	15	43	2	PS51011
Domain	ARID	ARID3C KDM5C	5.33e-04	15	43	2	PF01388
Domain	Ion_trans_dom	KCNQ3 RYR1 RYR3	2.29e-03	114	43	3	IPR005821
Domain	Ion_trans	KCNQ3 RYR1 RYR3	2.29e-03	114	43	3	PF00520
Domain	-	AIF1 SYNRG RYR1 RYR3	3.00e-03	261	43	4	1.10.238.10
Domain	EF-hand-dom_pair	AIF1 SYNRG RYR1 RYR3	4.21e-03	287	43	4	IPR011992
Pubmed	Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.	RYR1 RYR3	1.56e-06	2	44	2	12565913
Pubmed	Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.	RYR1 RYR3	1.56e-06	2	44	2	9489997
Pubmed	Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.	RYR1 RYR3	1.56e-06	2	44	2	9192302
Pubmed	The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.	RYR1 RYR3	1.56e-06	2	44	2	12640042
Pubmed	Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.	RYR1 RYR3	1.56e-06	2	44	2	7556644
Pubmed	Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.	RYR1 RYR3	1.56e-06	2	44	2	14592949
Pubmed	Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.	RYR1 RYR3	1.56e-06	2	44	2	15894801
Pubmed	Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.	RYR1 RYR3	1.56e-06	2	44	2	9799464
Pubmed	Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.	RYR1 RYR3	1.56e-06	2	44	2	9817784
Pubmed	Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.	RYR1 RYR3	1.56e-06	2	44	2	17118445
Pubmed	RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.	RYR1 RYR3	1.56e-06	2	44	2	11500519
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR3	4.69e-06	3	44	2	18403125
Pubmed	Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.	RYR1 RYR3	4.69e-06	3	44	2	11171121
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	RYR1 RYR3	4.69e-06	3	44	2	18313230
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR3	4.69e-06	3	44	2	18434746
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR3	4.69e-06	3	44	2	9204703
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR3	4.69e-06	3	44	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR3	4.69e-06	3	44	2	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR3	4.69e-06	3	44	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR3	4.69e-06	3	44	2	9242641
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR3	4.69e-06	3	44	2	22948152
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR3	4.69e-06	3	44	2	10788707
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR3	4.69e-06	3	44	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR3	4.69e-06	3	44	2	7621815
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR3	4.69e-06	3	44	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR3	4.69e-06	3	44	2	11159936
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR3	4.69e-06	3	44	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR3	4.69e-06	3	44	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR3	4.69e-06	3	44	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR3	4.69e-06	3	44	2	7635066
Pubmed	Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.	KIFAP3 ANK2 RYR1	7.49e-06	30	44	3	20080650
Pubmed	Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.	RYR1 RYR3	9.37e-06	4	44	2	22100703
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR3	9.37e-06	4	44	2	18206662
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR3	9.37e-06	4	44	2	23413940
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR3	9.37e-06	4	44	2	9384575
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR3	9.37e-06	4	44	2	9607712
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR3	9.37e-06	4	44	2	23482488
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	MTA2 MYOF MIA3 USP15 RPN2 HSPH1	1.07e-05	399	44	6	37536630
Pubmed	Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations.	PBRM1 KDM5C	1.56e-05	5	44	2	24029645
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR3	1.56e-05	5	44	2	23918386
Pubmed	A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.	KIFAP3 ANK2	1.56e-05	5	44	2	22632975
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR3	1.56e-05	5	44	2	19011160
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MTA2 AIF1 MYOF MIA3 CAV2 ITGAV USP15 RPN2 HSPH1	1.62e-05	1201	44	9	35696571
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR1 RYR3	2.34e-05	6	44	2	19549818
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	RYR1 RYR3	2.34e-05	6	44	2	26025922
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR1 RYR3	2.34e-05	6	44	2	23463619
Pubmed	Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.	RYR1 RYR3	2.34e-05	6	44	2	10444070
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR1 RYR3	2.34e-05	6	44	2	14592808
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR1 RYR3	2.34e-05	6	44	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR1 RYR3	2.34e-05	6	44	2	25966694
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR1 RYR3	2.34e-05	6	44	2	19009018
Pubmed	Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study.	FMN2 MIA3	2.34e-05	6	44	2	19955471
Pubmed	Tissue factor pathway inhibitor is required for cerebrovascular development in mice.	AIF1 F5	2.34e-05	6	44	2	32735640
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR1 RYR3	2.34e-05	6	44	2	16844763
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR1 RYR3	3.27e-05	7	44	2	11860456
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	RYR1 RYR3	3.27e-05	7	44	2	20962236
Pubmed	Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy.	FMN2 MIA3	4.36e-05	8	44	2	19336575
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 RYR3	4.36e-05	8	44	2	19033399
Pubmed	Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.	RYR1 RYR3	4.36e-05	8	44	2	21441923
Pubmed	ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.	RYR1 RYR3	4.36e-05	8	44	2	30563862
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	RYR1 RYR3	4.36e-05	8	44	2	11784029
Pubmed	Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.	RYR1 RYR3	5.60e-05	9	44	2	21858002
Pubmed	Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer.	PBRM1 KDM5C	5.60e-05	9	44	2	30355451
Pubmed	The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development.	AIF1 ITGAV	6.99e-05	10	44	2	35217866
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	RYR1 RYR3	1.02e-04	12	44	2	19095005
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	USP15 F5 TBX1 HSPH1	1.14e-04	197	44	4	20811636
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	KIFAP3 MIA3 PBRM1 WASHC4 ITGAV RPN2 STRIP1 EPM2AIP1	1.17e-04	1203	44	8	29180619
Pubmed	Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch.	MYOF USP15	1.21e-04	13	44	2	23146885
Pubmed	PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development.	AIF1 PBRM1	1.63e-04	15	44	2	37371026
Pubmed	Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia.	AIF1 ITGAV	2.10e-04	17	44	2	30647151
Pubmed	Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity.	USP15 STRIP1	2.10e-04	17	44	2	29299163
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	KCNQ3 ANK2	2.36e-04	18	44	2	37321992
Pubmed	Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome.	ZDHHC8 TBX1	2.36e-04	18	44	2	17097888
Pubmed	Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.	AIF1 PBRM1	2.64e-04	19	44	2	35173232
Pubmed	PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.	ANK2 RYR3	3.24e-04	21	44	2	39304345
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CDH9 RYR1	3.56e-04	22	44	2	26494785
Pubmed	A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.	TBX1 TNS3	3.89e-04	23	44	2	25217961
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	PBRM1 USP15 KDM5C HSPH1 STRIP1	4.23e-04	503	44	5	16964243
Pubmed	Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.	MTA2 PBRM1	4.24e-04	24	44	2	18454139
Pubmed	Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.	ZDHHC8 TBX1	4.24e-04	24	44	2	21821099
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	MTA2 USP15 HSPH1	4.67e-04	119	44	3	35776542
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ADK MYOF MIA3 RPN2 RYR1 HSPH1	5.10e-04	807	44	6	30575818
Pubmed	Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.	PAPPA CDH9	5.38e-04	27	44	2	24496616
Pubmed	Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region.	ZDHHC8 TBX1	5.79e-04	28	44	2	10963672
Pubmed	22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.	ZDHHC8 TBX1	6.21e-04	29	44	2	23077214
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	FMN2 CAV2 ANK2 ZDHHC8 TNS3	7.39e-04	569	44	5	30639242
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	MTA2 PBRM1 RPN2 ZNF639	8.01e-04	330	44	4	33301849
Pubmed	Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2.	ZDHHC8 TBX1	8.06e-04	33	44	2	10704284
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MTA2 MYOF WASHC4 TNS3 HSPH1 EPM2AIP1	9.54e-04	910	44	6	36736316
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	FMN2 ANK2 HSPH1 STRIP1	9.65e-04	347	44	4	17114649
Pubmed	Epicardial-myocardial signaling directing coronary vasculogenesis.	PBRM1 TBX1	1.01e-03	37	44	2	20299672
Pubmed	Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.	ZDHHC8 TBX1	1.01e-03	37	44	2	10337614
Pubmed	Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.	MYOF PBRM1 WASHC4	1.04e-03	157	44	3	12466305
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	MTA2 PBRM1 KDM5C	1.04e-03	157	44	3	30186101
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	RYR1 RYR3	1.07e-03	38	44	2	30786075
Pubmed	Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation.	KIFAP3 F5	1.13e-03	39	44	2	19064610
Pubmed	Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.	ZDHHC8 TBX1	1.24e-03	41	44	2	25452572
Cytoband	7p22.1	RSPH10B2 RSPH10B	9.44e-04	47	44	2	7p22.1
Cytoband	22q11.21	ZDHHC8 TBX1	5.13e-03	111	44	2	22q11.21
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR3	7.98e-06	3	30	2	287
GeneFamily	AT-rich interaction domain containing	ARID3C KDM5C	2.76e-04	15	30	2	418
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV F5 RYR3	6.60e-07	168	44	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-E_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	AIF1 MYOF CAV2 ANK2 HSPH1	1.48e-06	198	44	5	498f11441c0a0982738537bcfcfc2877866b7400
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 F5 RYR3	2.27e-05	168	44	4	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FMN2 ITGAV F5 RYR3	2.27e-05	168	44	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 F5 RYR3	2.48e-05	172	44	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	droplet-Marrow-nan-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 ABCA3 CAV2 TNS3	2.54e-05	173	44	4	6d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 F5 RYR3	2.78e-05	177	44	4	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 F5 RYR3	2.84e-05	178	44	4	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADK KCNQ3 MYOF ABCA3	3.03e-05	181	44	4	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KCNQ3 CACNG4 ABCA3 CAV2	3.17e-05	183	44	4	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FMN2 ANK2 TBX1 FAM149A	3.37e-05	186	44	4	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV RYR3	3.44e-05	187	44	4	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV F5	3.52e-05	188	44	4	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FMN2 ANK2 TBX1 FAM149A	3.52e-05	188	44	4	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV F5	3.52e-05	188	44	4	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV F5	3.82e-05	192	44	4	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 ITGAV F5	3.90e-05	193	44	4	3eaa0461618582a1754400624350d269d24e750a
ToppCell	368C\|World / Donor, Lineage, Cell class and subclass (all cells)	AIF1 PAPPA ANK2 HSPH1	4.22e-05	197	44	4	f41211923938e5d7bfe6bf24f604ab386f17ef10
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Astrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMN2 ANK2 ITGAV RYR3	4.22e-05	197	44	4	5bcf963f21d23edafef1e90dc1de24cd3b0fccce
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMN2 ANK2 ITGAV RYR3	4.22e-05	197	44	4	bd7e18a0fed085cfb8ed0e478d1f172a173febbe
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FMN2 ANK2 ITGAV RYR3	4.22e-05	197	44	4	7e06aee2add54eeff4a9927d9b04b5797160113b
ToppCell	moderate-Epithelial-Secretory\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYOF MIA3 CAV2 RPN2	4.30e-05	198	44	4	7ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 PBRM1 CAV2 ALKBH5	4.30e-05	198	44	4	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 PBRM1 CAV2 ALKBH5	4.30e-05	198	44	4	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FMN2 KIFAP3 KCNQ3 PREPL	4.30e-05	198	44	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTA2 PBRM1 CAV2 ALKBH5	4.39e-05	199	44	4	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c10-IFNG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FMN2 ANK2 RSPH10B	2.61e-04	126	44	3	d19382597ce5c6546731ac1fd33c7dcb7916b2ea
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGAV RYR1 RYR3	2.61e-04	126	44	3	9b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMN2 NPY1R RYR3	2.74e-04	128	44	3	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CACNG4 CDH9 TNS3	3.13e-04	134	44	3	d63fff23040eada31bc35ba1e05b7c6a663e0037
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGAV RYR1 RYR3	3.13e-04	134	44	3	cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PCDHA11 MYOF RYR3	3.34e-04	137	44	3	25b5370b63644351efddb8749ef174beca0581cd
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PCDHA11 RSPH10B RYR3	3.41e-04	138	44	3	05de2cef97c0912fb23f138dd45348f565a14d74
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NPY1R CAV2 RYR3	3.86e-04	144	44	3	7de962346ba9653d90dd13bb7d977fe44d200bba
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MIA3 RYR1 RYR3	3.86e-04	144	44	3	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	Ciliated_cells-A-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ODAD4 CACNG4 RSPH10B	4.70e-04	154	44	3	3b938e23324f7edb56797b4a76fb96ff588142cf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN2 F5 RYR3	4.79e-04	155	44	3	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN2 F5 RYR3	4.79e-04	155	44	3	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN2 F5 RYR3	4.79e-04	155	44	3	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RSPH10B2 CACNG4 FAM149A	4.97e-04	157	44	3	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AIF1 KCNQ3 FAM149A	4.97e-04	157	44	3	d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	FMN2 ANK2 RYR3	5.16e-04	159	44	3	f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD4+_Th\|normal_Pleural_Fluid / Location, Cell class and cell subclass	ABCA3 ANK2 RYR1	5.16e-04	159	44	3	ebd840ac2b07e62086ee7b5bb01c21804a0fdc7b
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AIF1 RYR1 FAM149A	5.35e-04	161	44	3	76c993a4533362db2250c88b3ee3ede55362d54e
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 ANK2 FAM149A	5.35e-04	161	44	3	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	AT1_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	CACNG4 CAV2 ANK2	5.45e-04	162	44	3	ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell	AT1-AT2_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	PAPPA CAV2 ANK2	5.45e-04	162	44	3	57d627259d27f39885bf416d74bcb6656db6e27b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	ADK ABCA3 FAM149A	5.54e-04	163	44	3	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FMN2 NPY1R F5	5.95e-04	167	44	3	c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AIF1 MYOF ASB4	5.95e-04	167	44	3	589c0acfeb4d70931b6726fb3331d85a54e74d56
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	5.95e-04	167	44	3	f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	F5 KDM5C HSPH1	5.95e-04	167	44	3	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	ABCA3 TBX1 RYR3	6.05e-04	168	44	3	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ3 ODAD4 RSPH10B	6.05e-04	168	44	3	fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KCNQ3 ODAD4 RSPH10B	6.05e-04	168	44	3	7edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	KIFAP3 ABCA3 ITGAV	6.05e-04	168	44	3	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7\|TCGA-Lung / Sample_Type by Project: Shred V9	SCP2 KCNQ3 FAM149A	6.16e-04	169	44	3	5f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	6.16e-04	169	44	3	46f0f0de9a0894c454f93032e7a7a800f47c8276
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AIF1 RYR1 FAM149A	6.16e-04	169	44	3	9c9bb1b32fc6e22359424a262178906c3954415d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AIF1 RYR1 FAM149A	6.26e-04	170	44	3	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 MYOF FAM149A	6.26e-04	170	44	3	067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCell	droplet-Spleen-SPLEEN-1m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 ANK2 TNS3	6.26e-04	170	44	3	670027daec5a10dfa12246f1497b58db21d32a22
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 TNS3 RYR3	6.37e-04	171	44	3	4a2e6ea9674bf23e8012ef0bb2bf19ce1f55fcd5
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ODAD4 CACNG4 TBX1	6.37e-04	171	44	3	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	droplet-Spleen-nan-18m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 TNS3 RYR3	6.48e-04	172	44	3	850e4c9e9003807c19695be4b13121b0808a9389
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	6.48e-04	172	44	3	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	facs-Marrow-KLS-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 TNS3 FAM149A	6.48e-04	172	44	3	979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCell	droplet-Spleen-nan-18m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 TNS3 RYR3	6.48e-04	172	44	3	018d8160cfcb7882475620dc678f48a69a0f643e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 RYR3	6.48e-04	172	44	3	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	facs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 TNS3 FAM149A	6.48e-04	172	44	3	f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	ZDHHC8 TNS3 STRIP1	6.59e-04	173	44	3	67f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCell	droplet-Thymus-nan-24m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 MYOF F5	6.70e-04	174	44	3	44c21521991ad4789783d73d5aa4993a22876886
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AIF1 RYR1 FAM149A	6.70e-04	174	44	3	6688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	6.70e-04	174	44	3	2afa5eea54b67c549c5058ece98296eee3829c11
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 RYR3	6.70e-04	174	44	3	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MTA2 TBX1 RSPH10B	6.81e-04	175	44	3	9a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FMN2 F5 RYR3	6.81e-04	175	44	3	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	FMN2 ANK2 F5	6.81e-04	175	44	3	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MTA2 TBX1 RSPH10B	6.81e-04	175	44	3	54c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MTA2 TBX1 RSPH10B	6.81e-04	175	44	3	2b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCell	facs-Skin-nan-24m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNG4 TBX1 TNS3	6.81e-04	175	44	3	f1166b567bca80dac3abe90c3dc544c831006640
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	FMN2 ANK2 F5	6.81e-04	175	44	3	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	AT1-AT2_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CACNG4 CAV2 ANK2	6.81e-04	175	44	3	9a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	KCNQ3 SYNRG MYOF	6.93e-04	176	44	3	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	RSPH10B2 PAPPA ANK2	6.93e-04	176	44	3	bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RSPH10B2 PAPPA ANK2	7.04e-04	177	44	3	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	wk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCDHA11 NPY1R CDH9	7.04e-04	177	44	3	15a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	7.04e-04	177	44	3	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PAPPA ASB4 ANK2	7.16e-04	178	44	3	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ODAD4 TNS3 HSPH1	7.16e-04	178	44	3	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AIF1 RYR1 FAM149A	7.16e-04	178	44	3	8c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PAPPA ASB4 ANK2	7.16e-04	178	44	3	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNQ3 ITGAV RYR3	7.16e-04	178	44	3	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	Mild-Treg\|Mild / Disease group and Cell class	F5 TNS3 FAM149A	7.16e-04	178	44	3	e669fd95278e145f55126d0e6be8fb2d6184dbbd
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AIF1 RYR1 FAM149A	7.27e-04	179	44	3	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	KIFAP3 KCNQ3 PREPL	7.27e-04	179	44	3	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPY1R CAV2 RYR3	7.39e-04	180	44	3	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AIF1 FMN2 F5	7.39e-04	180	44	3	d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCell	AT1-AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	PAPPA CACNG4 ANK2	7.39e-04	180	44	3	3c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYOF CDH9 RYR3	7.39e-04	180	44	3	e8841ef1239f9ee73ac4f4e11faca0742694f368
Drug	PCB 95	ADK RYR1 RYR3	8.00e-07	10	44	3	CID000038012
Drug	5'-adenylyl (beta,gamma-methylene)diphosphonate	RYR1 RYR3	3.65e-06	2	44	2	ctd:C005147
Drug	2-hydroxycarbazole	RYR1 RYR3	1.09e-05	3	44	2	CID000093551
Drug	1,1'-diheptyl-4,4'-bipyridinium	RYR1 RYR3	1.09e-05	3	44	2	CID000080262
Drug	cis-diammineplatinum(II	RYR1 RYR3	1.09e-05	3	44	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR3	1.09e-05	3	44	2	CID002750949
Drug	flubendiamide	RYR1 RYR3	1.09e-05	3	44	2	CID011193251
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR3	1.09e-05	3	44	2	CID005748312
Drug	8N3-cADPR	RYR1 RYR3	1.09e-05	3	44	2	CID000127713
Drug	aminodantrolene	RYR1 RYR3	1.09e-05	3	44	2	CID009570289
Drug	A-30	RYR1 RYR3	2.18e-05	4	44	2	CID003028528
Drug	PCB74	RYR1 RYR3	2.18e-05	4	44	2	CID000036218
Drug	148504-47-6	RYR1 RYR3	2.18e-05	4	44	2	CID006444275
Drug	Bastadin 10	RYR1 RYR3	2.18e-05	4	44	2	CID009589366
Drug	SC 38249	RYR1 RYR3	2.18e-05	4	44	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR3	2.18e-05	4	44	2	CID000035682
Drug	2,4-xylidinothiazoline	SAGE1 RYR1 RYR3	2.64e-05	30	44	3	CID000099296
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA	MTA2 NPY1R CAV2 PDE6B KDM5C	3.37e-05	192	44	5	849_DN
Drug	CNS 1145	CACNG4 RYR1 RYR3	3.53e-05	33	44	3	CID000190902
Drug	IHC-64	CACNG4 RYR1 RYR3	3.53e-05	33	44	3	CID000162753
Drug	carbamazepine; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	MTA2 NPY1R CAV2 WASHC4 ZNF639	3.54e-05	194	44	5	952_DN
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; HL60; HG-U133A	KIFAP3 MYOF CACNG4 PREPL EPM2AIP1	3.81e-05	197	44	5	2022_DN
Drug	Bumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A	MTA2 ADK KIFAP3 NPY1R F5	3.81e-05	197	44	5	7440_UP
Drug	borate	MTA2 SAGE1 RYR1 RYR3	3.84e-05	98	44	4	CID000007628
Drug	ICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA	MTA2 KIFAP3 MIA3 KDM5C ZNF639	3.99e-05	199	44	5	985_UP
Drug	MBED	RYR1 RYR3	5.45e-05	6	44	2	CID000129958
Drug	chloro-m-cresol	RYR1 RYR3	5.45e-05	6	44	2	CID000012008
Drug	AC1O528X	RYR1 RYR3	5.45e-05	6	44	2	CID006475857
Drug	NSC114784	RYR1 RYR3	5.45e-05	6	44	2	CID000419425
Drug	NSC692750	RYR1 RYR3	5.45e-05	6	44	2	CID000078910
Drug	Azumoleno	RYR1 RYR3	7.62e-05	7	44	2	CID000056259
Drug	mag-indo-1	RYR1 RYR3	7.62e-05	7	44	2	CID000131881
Drug	Br2BAPTA	RYR1 RYR3	7.62e-05	7	44	2	CID003081001
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR3	7.62e-05	7	44	2	CID009547999
Drug	CHEBI:564108	RYR1 RYR3	7.62e-05	7	44	2	CID006400637
Drug	DHBT	SYNRG PBRM1 CAV2 RYR1	8.19e-05	119	44	4	CID000001855
Drug	lactosyl lysosphingolipid	RYR1 RYR3	1.30e-04	9	44	2	CID006439268
Drug	FLA 365	RYR1 RYR3	1.30e-04	9	44	2	CID000072776
Drug	lanthanum	CACNG4 KDM5C RYR1 RYR3	1.37e-04	136	44	4	CID000023926
Drug	AC1N38XE	RYR1 RYR3	1.63e-04	10	44	2	CID004060965
Drug	Cinildipine	CACNG4 RYR1 RYR3	1.74e-04	56	44	3	CID000002752
Drug	4-hydroxyacetophenone	ADK SAGE1 CAV2	1.74e-04	56	44	3	CID000007469
Drug	BAPNA	PBRM1 RYR1 RYR3	1.83e-04	57	44	3	CID000013494
Drug	AC1N9ZZC	SCP2 ANK2 RYR1 RYR3	1.95e-04	149	44	4	CID004369374
Drug	PCB 66	RYR1 RYR3	1.99e-04	11	44	2	CID000036185
Drug	R 478	RYR1 RYR3	1.99e-04	11	44	2	CID000084223
Drug	8-amino-cADPR	RYR1 RYR3	1.99e-04	11	44	2	CID003081323
Drug	Bay K 8644	CACNG4 CAV2 RYR1 RYR3	2.00e-04	150	44	4	CID000002303
Drug	nilvadipine	CACNG4 RYR1 RYR3	2.13e-04	60	44	3	CID000004494
Drug	IAA-94	CACNG4 RYR1 RYR3	2.24e-04	61	44	3	CID000003667
Drug	manganese chloride	AIF1 PAPPA ITGAV USP15 PDE6B TBX1	2.31e-04	456	44	6	ctd:C025340
Drug	Ryanodine	RYR1 RYR3	2.38e-04	12	44	2	ctd:D012433
Drug	lercanidipine	CACNG4 RYR1 RYR3	2.47e-04	63	44	3	CID000065866
Drug	mibefradil	CACNG4 RYR1 RYR3	2.58e-04	64	44	3	CID000060662
Drug	AC1L1DXE	CACNG4 ANK2 TBX1 RYR1 RYR3	2.70e-04	299	44	5	CID000002548
Drug	NSC299933	RYR1 RYR3	2.81e-04	13	44	2	CID000431902
Drug	gallopamil	CACNG4 RYR1 RYR3	2.96e-04	67	44	3	CID000001234
Drug	NSC-695672	ADK RYR1 RYR3	2.96e-04	67	44	3	CID000393593
Drug	felodipine	CACNG4 PDE6B RYR1 RYR3	3.15e-04	169	44	4	CID000003333
Drug	AC1L2AC7	CACNG4 RYR1 RYR3	3.23e-04	69	44	3	CID000068733
Drug	bimoclomol	RYR1 RYR3	3.27e-04	14	44	2	CID009576891
Drug	NP-EGTA	RYR1 RYR3	3.27e-04	14	44	2	CID000183793
Drug	papaverine	CACNG4 PDE6B RYR1 RYR3	3.68e-04	176	44	4	CID000004680
Drug	FPL 64176	RYR1 RYR3	3.77e-04	15	44	2	CID000003423
Drug	Gvapspat amide	RYR1 RYR3	3.77e-04	15	44	2	CID000125015
Drug	CAS 298-57-7	CACNG4 RYR1 RYR3	3.81e-04	73	44	3	CID000002761
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	ABCA3 PDE6B HSPH1 ZNF639	3.92e-04	179	44	4	6184_UP
Drug	ethosuximide	CACNG4 RYR1 RYR3	3.97e-04	74	44	3	CID000003291
Drug	DM-nitrophen	RYR1 RYR3	4.31e-04	16	44	2	CID000003083
Drug	Ethacrynic acid [58-54-8]; Up 200; 13.2uM; HL60; HG-U133A	KIFAP3 SYNRG WASHC4 PREPL	4.63e-04	187	44	4	1565_UP
Drug	nisoldipine	CACNG4 RYR1 RYR3	4.63e-04	78	44	3	CID000004499
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNG4 RYR1 RYR3	4.81e-04	79	44	3	CID005287890
Drug	kazinol B	RYR1 RYR3	4.87e-04	17	44	2	CID000480869
Drug	Naftopidil dihydrochloride [57149-08-3]; Up 200; 8.6uM; HL60; HT_HG-U133A	PAPPA CACNG4 CAV2 ZNF639	4.91e-04	190	44	4	2911_UP
Drug	NSC759576	ADK CACNG4 RYR1 RYR3	5.01e-04	191	44	4	CID000003075
Drug	dihydropyridine	CACNG4 ANK2 RYR1 RYR3	5.21e-04	193	44	4	CID000104822
Drug	ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA	MTA2 NPY1R HSPH1 ZNF639	5.21e-04	193	44	4	979_DN
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; PC3; HT_HG-U133A	MYOF ABCA3 NPY1R ZNF639	5.21e-04	193	44	4	5074_DN
Drug	Etifenin [63245-28-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A	MYOF MIA3 PDE6B FAM149A	5.31e-04	194	44	4	4117_UP
Drug	17-AAG; Up 200; 1uM; PC3; HG-U133A	KIFAP3 CACNG4 NPY1R HSPH1	5.42e-04	195	44	4	450_UP
Drug	Xylazine [7361-61-7]; Up 200; 18.2uM; HL60; HT_HG-U133A	MTA2 PAPPA F5 RYR1	5.42e-04	195	44	4	2132_UP
Drug	radicicol; Up 200; 0.1uM; PC3; HT_HG-U133A	ADK SYNRG HSPH1 ZNF639	5.42e-04	195	44	4	5952_UP
Drug	methylcoumarin	RYR1 RYR3	5.48e-04	18	44	2	CID000007092
Drug	Benzamil hydrochloride [2898-76-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	CACNG4 TBX1 ZNF639 FAM149A	5.52e-04	196	44	4	3738_UP
Drug	chlorpromazine hydrochloride; Down 200; 10uM; MCF7; HG-U133A	ADK CACNG4 WASHC4 EPM2AIP1	5.52e-04	196	44	4	419_DN
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A	MYOF ABCA3 NPY1R TBX1	5.52e-04	196	44	4	4469_DN
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	CACNG4 NPY1R CAV2 TNS3	5.63e-04	197	44	4	2812_DN
Drug	Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A	MYOF CACNG4 F5 ZNF639	5.63e-04	197	44	4	6350_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; PC3; HT_HG-U133A	PAPPA CACNG4 PDE6B FAM149A	5.63e-04	197	44	4	4618_UP
Drug	Gliclazide [21187-98-4]; Up 200; 12.4uM; PC3; HT_HG-U133A	PAPPA CACNG4 PBRM1 TBX1	5.63e-04	197	44	4	5089_UP
Drug	Sulfachloropyridazine [80-32-0]; Up 200; 14uM; HL60; HT_HG-U133A	MTA2 KCNQ3 RYR1 RYR3	5.63e-04	197	44	4	2191_UP
Drug	Enoxacin [74011-58-8]; Up 200; 12.4uM; HL60; HG-U133A	ADK SCP2 KIFAP3 EPM2AIP1	5.63e-04	197	44	4	1597_UP
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; HL60; HT_HG-U133A	MTA2 PAPPA CACNG4 ZNF639	5.63e-04	197	44	4	3045_UP
Drug	Metrizamide [31112-62-6]; Up 200; 5uM; MCF7; HT_HG-U133A	MTA2 MYOF MIA3 NPY1R	5.63e-04	197	44	4	3255_UP
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	MTA2 SYNRG MYOF WASHC4	5.63e-04	197	44	4	6999_DN
Drug	Bezafibrate [41859-67-0]; Up 200; 11uM; PC3; HT_HG-U133A	PAPPA CACNG4 F5 ZNF639	5.63e-04	197	44	4	6653_UP
Drug	Vidarabine [5536-17-4]; Up 200; 15uM; MCF7; HT_HG-U133A	MTA2 MYOF CACNG4 ZNF639	5.63e-04	197	44	4	3445_UP
Drug	Nadide [53-84-9]; Down 200; 6uM; HL60; HT_HG-U133A	MTA2 CAV2 ANK2 F5	5.74e-04	198	44	4	2529_DN
Drug	Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HT_HG-U133A	CACNG4 TBX1 RYR1 ZNF639	5.74e-04	198	44	4	4074_UP
Drug	Flutamide [13311-84-7]; Up 200; 14.4uM; HL60; HT_HG-U133A	PAPPA CACNG4 ANK2 TBX1	5.74e-04	198	44	4	2358_UP
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR3	5.93e-06	3	42	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR3	5.93e-06	3	42	2	DOID:8545 (implicated_via_orthology)
Disease	Papillary Renal Cell Carcinoma	FMN2 PBRM1 KDM5C RYR1	3.33e-05	128	42	4	C1306837
Disease	Renal Cell Carcinoma	FMN2 PBRM1 KDM5C RYR1	3.33e-05	128	42	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	FMN2 PBRM1 KDM5C RYR1	3.33e-05	128	42	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	FMN2 PBRM1 KDM5C RYR1	3.33e-05	128	42	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	FMN2 PBRM1 KDM5C RYR1	3.33e-05	128	42	4	C1266044
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	FMN2 PBRM1 KDM5C RYR1	5.86e-05	148	42	4	C0279702
Disease	Acute Cerebrovascular Accidents	ANK2 ITGAV F5	6.32e-05	54	42	3	C0751956
Disease	Cerebrovascular accident	ANK2 ITGAV F5	9.57e-05	62	42	3	C0038454
Disease	Nonorganic psychosis	NPY1R PBRM1 TBX1	1.32e-04	69	42	3	C0349204
Disease	intellectual disability (implicated_via_orthology)	ANK2 ITGAV KDM5C	1.69e-04	75	42	3	DOID:1059 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	PBRM1 KDM5C RYR1 RYR3	1.70e-04	195	42	4	DOID:1574 (implicated_via_orthology)
Disease	Myocardial Infarction	PAPPA MIA3 F5	3.39e-04	95	42	3	C0027051
Disease	temporal lobe epilepsy (is_marker_for)	ADK NPY1R	3.70e-04	20	42	2	DOID:3328 (is_marker_for)
Disease	Psychotic Disorders	NPY1R PBRM1 TBX1	4.06e-04	101	42	3	C0033975
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	KIFAP3 F5	4.08e-04	21	42	2	EFO_0004286, EFO_0004792
Disease	venous thromboembolism, tissue plasminogen activator measurement	KIFAP3 F5	4.91e-04	23	42	2	EFO_0004286, EFO_0004791
Disease	sensorineural hearing loss (is_implicated_in)	F5 TBX1	1.02e-03	33	42	2	DOID:10003 (is_implicated_in)
Disease	LDL peak particle diameter measurement, total fat intake measurement	KCNQ3 MIA3	1.08e-03	34	42	2	EFO_0007677, EFO_0007678
Disease	autism spectrum disorder (implicated_via_orthology)	ABCA3 KDM5C TBX1	1.33e-03	152	42	3	DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DKDFLDKYSLKPNDQ	ADK	41	P55263
EEQFKQLYELDADPK	ARID3C	101	A6NKF2
YKAEVNARDDDFKSP	ASB4	241	Q9Y574
AKRKYQEDSDPERSD	ALKBH5	56	Q6P6C2
EDSDPEKALRNEYFE	ABCA3	506	Q99758
EKYGKDFNDIRQDFL	MTA2	281	O94776
DRSYDKLNRDTDQPK	ANK2	2756	Q01484
KYERPKDDREEEFNT	RSPH10B	746	P0C881
KYERPKDDREEEFNT	RSPH10B2	746	B2RC85
NDNDPEFDKSEYKVS	PCDHA11	236	Q9Y5I1
KEYFKLCPENFRDED	PBRM1	1041	Q86U86
PAYFADRTQNEKEDK	FAM149A	561	A5PLN7
LKKDYDDFRRQPDHD	KIAA2026	836	Q5HYC2
PAEAEKKEDNRYSDL	KCNQ3	666	O43525
NDPFIQKEKENLSYD	HSPH1	76	Q92598
FYNRKDGKPFDEQDE	PDE6B	401	P35913
SDQDNKDPRYFFSLK	PAPPA	161	Q13219
DEPFQNVTLDAYKDK	NPY1R	181	P25929
DPSDKRDEDKKNHYN	CACNG4	166	Q9UBN1
QQNKEDEKIFDPDRY	EPM2AIP1	446	Q7L775
GNRDYAKDDPLEFKS	ITGAV	106	P06756
EYADPEKFADSDQDR	CAV2	26	P51636
ENAKSLDKPEQFLYE	FMN2	1426	Q9NZ56
RKFYNKSEDEDEPDM	RYR1	4861	P21817
DINDNEPKFTKDLYT	CDH9	151	Q9ULB4
DPENQTLRKDYEKTF	KIFAP3	251	Q92845
ENRDYKDFTKQDLPT	SYNRG	981	Q9UMZ2
QNKDSDYLKNDNPEE	MIA3	846	Q5JRA6
DEVKRDDPKFYESNI	F5	571	P12259
KEYDLPDAKSRALDN	ODAD4	351	Q96NG3
QDNLDAFNERDPYKA	STRIP1	361	Q5VSL9
AFNERDPYKADDSRE	STRIP1	366	Q5VSL9
NASKDDRFPDYGKVE	TNS3	281	Q68CZ2
NSRDYPDLAEEAGKK	SCP2	31	P22307
EINKQFLDDPKYSSD	AIF1	26	P55008
RQPDLKYFDNKDDDS	ZNF639	46	Q9UID6
AEPDNKNVYKFELDT	RPN2	451	P04844
SKDELLYKPDSNEFA	SAGE1	771	Q9NXZ1
FFRKFYNKSEDDDEP	RYR3	4691	Q15413
DLKKRYFDENAAEDF	USP15	756	Q9Y4E8
GDNKRNERFYTEKDP	PREPL	236	Q4J6C6
IKDQNDHKYPFDRAE	WASHC4	876	Q2M389
DKEDDFRAPLYKNVD	ZDHHC8	81	Q9ULC8
VDPRKDSEKYAEENF	TBX1	246	O43435
CNTRPFDNEEKDKEY	KDM5C	176	P41229
FKLYRGKSDENEDPS	MYOF	1501	Q9NZM1