Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTBC

TBC1D15 EVI5L

2.80e-0349302SM00164
DomainRabGAP-TBC

TBC1D15 EVI5L

3.27e-0353302PF00566
DomainTBC_RABGAP

TBC1D15 EVI5L

3.51e-0355302PS50086
DomainRab-GTPase-TBC_dom

TBC1D15 EVI5L

3.51e-0355302IPR000195
DomainRhoGEF

ARHGEF33 FGD6

5.32e-0368302SM00325
DomainDH_2

ARHGEF33 FGD6

5.63e-0370302PS50010
DomainRhoGEF

ARHGEF33 FGD6

5.63e-0370302PF00621
DomainDH-domain

ARHGEF33 FGD6

5.79e-0371302IPR000219
Domain-

ARHGEF33 FGD6

5.79e-03713021.20.900.10
DomainZnf_RING/FYVE/PHD

BIRC3 USP45 DTX3L FGD6

5.95e-03459304IPR013083
Domain-

COL6A6 ITGB4

6.27e-03743023.40.50.410
DomainVWFA

COL6A6 ITGB4

7.65e-0382302PS50234
DomainVWA

COL6A6 ITGB4

8.01e-0384302SM00327
DomainVWF_A

COL6A6 ITGB4

1.10e-0299302IPR002035
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

TBC1D15 DDX60L PFKM PRRC2C SDAD1 EVI5L BAG5 PANK4 NOC3L

3.08e-06144031930833792
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

TBC1D15 PFKM ORC3 SDAD1 PANK4

1.28e-0456031535241646
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

BIRC3 TBC1D15 PFKM HSP90AB4P DNAH5 SDAD1 NOC3L

2.11e-04142531730948266
Pubmed

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.

DTX3L PANK4

3.29e-043031234285210
Pubmed

Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma.

BIRC3 BAG5

4.49e-043531220855536
Pubmed

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.

PFKM ITGB4

5.87e-044031238418556
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

RLF TBC1D15 DTX3L ORC3 SDAD1 NOC3L

5.93e-04120331629180619
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

TBC1D15 EVI5L

6.79e-044331219077034
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

TBC1D15 EVI5L

6.79e-044331217646400
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

PFKM DNAH5 SDAD1

8.38e-0420831333230847
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF33 FGD6

2.16e-0366192722
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

BIRC3 DDX60L DTX3L INHBA FGD6

1.64e-071833158f7f5000645f24f20a8d7700c4df1f8953a1780b
DiseaseX-12063 measurement

STK31 DNAH5 KCTD8

9.73e-04186313EFO_0021283
Diseaselongevity

STK10 PFKM SDAD1

3.25e-03284313EFO_0004300
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

STK10 PTPRA PROS1

5.91e-03352313EFO_0007015
Diseaseverbal-numerical reasoning measurement

STK31 BAG5

8.36e-03131312EFO_0008394

Protein segments in the cluster

PeptideGeneStartEntry
KQAEAECKSKEEVMA

EVI5L

631

Q96CN4
ICAVQEIIEDCMKKQ

BAG5

156

Q9UL15
EKVKSCRCSMEEKVT

ARHGEF33

56

A8MVX0
LQEERTCKVCMDKEV

BIRC3

551

Q13489
KVVMLVEECQCKVKT

CER1

231

O95813
IKKDIQNMIVEECGC

INHBA

411

P08476
CEKLSVEEEMKKCIQ

KCTD8

431

Q6ZWB6
KCTMCKEKLEREAAE

SPINK5

806

Q9NQ38
VSCMKEAQKSICDII

HSP90AB4P

381

Q58FF6
ADKIMEEKCISEKQA

DDX60L

921

Q5H9U9
TDMCKKLFEVEEVNC

PNLIPRP1

106

P54315
CVQVTKDVTKAMDEK

PFKM

351

P08237
RTCEECNFKVKMVDE

ITGB4

646

P16144
KVDKEDVMTCLIKGC

PANK4

141

Q9NVE7
SELDKKEKGICVICM

DTX3L

551

Q8TDB6
VVQEICTEEACKEMK

COL6A6

606

A6NMZ7
DCSLEIKKEVVQCMG

DNAH5

3136

Q8TE73
IVMVTNLKERKECKC

PTPRA

336

P18433
LISEMCCEAVKKLFK

NOC3L

376

Q8WTT2
MDCCVDIKSKEEESV

ORC3

156

Q9UBD5
EEMLKTEEACKAIDK

NRK

1296

Q7Z2Y5
ELQKMKEQEKECELE

PRRC2C

576

Q9Y520
LKQLECCKERFEVKM

SDAD1

301

Q9NVU7
VMLSNKKDCKDVDEC

PROS1

191

P07225
TKEEMIQRINKCCED

SIX6OS1

26

Q8N1H7
EEIKTENLDKCMEKT

STK31

996

Q9BXU1
MKLCEEKCETDEIQK

USP45

166

Q70EL2
EDEEMKASVCKTIAC

RLF

386

Q13129
ICDKERECLMKKQEL

STK10

721

O94804
LSAMDVEKCTKPCKD

FGD6

606

Q6ZV73
CCAILESEKQQIMEK

TBC1D15

566

Q8TC07
DLITCLEKEKEPCKM

ZNF429

51

Q86V71
ETLVKDCIKEVCLEM

ZBED9

841

Q6R2W3