Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD2 RGPD1 UBE2I MUL1	6.30e-05	36	120	4	GO:0019789
GeneOntologyMolecularFunction	fructose-bisphosphate aldolase activity	ALDOA ALDOC	1.07e-04	3	120	2	GO:0004332
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO1B3 SLCO1B7 SLCO4C1	1.62e-04	18	120	3	GO:0015347
GeneOntologyMolecularFunction	carbon-carbon lyase activity	BCKDHA ALDOA ALDOC HDC	3.58e-04	56	120	4	GO:0016830
GeneOntologyBiologicalProcess	regulation of defecation	NPSR1 CRHR2	3.14e-05	2	116	2	GO:2000292
GeneOntologyBiologicalProcess	negative regulation of defecation	NPSR1 CRHR2	3.14e-05	2	116	2	GO:2000293
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO1B3 SLCO1B7 SLCO4C1	7.51e-05	15	116	3	GO:0043252
GeneOntologyBiologicalProcess	monoatomic ion transport	ATP5F1E SESTD1 HTR2C PMPCB CAMK2A NPSR1 OTOP2 SLCO1B3 ATP10A CRHR2 SLCO1B7 ADRA1A SLCO4C1 KCNE1 KCNG4 SCN7A UBR3 LRRC8B EPB41 ATP5F1EP2	7.71e-05	1374	116	20	GO:0006811
Domain	OA_transporter	SLCO1B3 SLCO1B7 SLCO4C1	5.19e-05	12	118	3	IPR004156
Domain	OATP	SLCO1B3 SLCO1B7 SLCO4C1	5.19e-05	12	118	3	PF03137
Domain	FBA_I	ALDOA ALDOC	1.18e-04	3	118	2	IPR000741
Domain	Glycolytic	ALDOA ALDOC	1.18e-04	3	118	2	PF00274
Domain	Aldolase_I_AS	ALDOA ALDOC	1.18e-04	3	118	2	IPR029768
Domain	ALDOLASE_CLASS_I	ALDOA ALDOC	1.18e-04	3	118	2	PS00158
Domain	Peptidase_M13_C	ECE1 ECEL1	8.14e-04	7	118	2	IPR018497
Domain	Peptidase_M13	ECE1 ECEL1	8.14e-04	7	118	2	IPR000718
Domain	Peptidase_M13_N	ECE1 ECEL1	8.14e-04	7	118	2	PF05649
Domain	Peptidase_M13_N	ECE1 ECEL1	8.14e-04	7	118	2	IPR008753
Domain	Rab_bind	RGPD2 RGPD1	8.14e-04	7	118	2	PF16704
Domain	GCC2_Rab_bind	RGPD2 RGPD1	8.14e-04	7	118	2	IPR032023
Domain	Peptidase_M13	ECE1 ECEL1	8.14e-04	7	118	2	PF01431
Domain	MYTH4	PLEKHH1 MYO15A	1.38e-03	9	118	2	PS51016
Domain	MyTH4	PLEKHH1 MYO15A	1.38e-03	9	118	2	SM00139
Domain	MyTH4_dom	PLEKHH1 MYO15A	1.38e-03	9	118	2	IPR000857
Domain	MyTH4	PLEKHH1 MYO15A	1.38e-03	9	118	2	PF00784
Domain	Kazal_2	SLCO1B3 SLCO1B7 SLCO4C1	1.51e-03	36	118	3	PF07648
Domain	FN3	COL6A3 DSCAM MDGA2 ROS1 EPHA10 EPHB1	1.66e-03	199	118	6	PS50853
Domain	-	RGPD2 RGPD1	1.72e-03	10	118	2	1.10.220.60
Domain	-	ECE1 ADAMTS10 ADAMTS6 ECEL1	1.73e-03	81	118	4	3.40.390.10
Domain	MetalloPept_cat_dom	ECE1 ADAMTS10 ADAMTS6 ECEL1	1.73e-03	81	118	4	IPR024079
Domain	IQ	CAMTA2 SCN7A ASPM MYO15A	1.73e-03	81	118	4	SM00015
Domain	IL-1_rcpt_fam	IL18R1 IL1RAPL2	2.10e-03	11	118	2	IPR015621
Domain	Grip	RGPD2 RGPD1	2.10e-03	11	118	2	SM00755
Domain	GRIP	RGPD2 RGPD1	2.10e-03	11	118	2	PF01465
Domain	FN3_dom	COL6A3 DSCAM MDGA2 ROS1 EPHA10 EPHB1	2.13e-03	209	118	6	IPR003961
Domain	Ran_BP1	RGPD2 RGPD1	2.51e-03	12	118	2	PF00638
Domain	RANBD1	RGPD2 RGPD1	2.51e-03	12	118	2	PS50196
Domain	GRIP_dom	RGPD2 RGPD1	2.51e-03	12	118	2	IPR000237
Domain	GRIP	RGPD2 RGPD1	2.51e-03	12	118	2	PS50913
Domain	IQ_motif_EF-hand-BS	CAMTA2 SCN7A ASPM MYO15A	2.55e-03	90	118	4	IPR000048
Domain	RanBD	RGPD2 RGPD1	2.95e-03	13	118	2	SM00160
Domain	Ran_bind_dom	RGPD2 RGPD1	2.95e-03	13	118	2	IPR000156
Domain	FERM_M	PLEKHH1 MYO15A EPB41	3.06e-03	46	118	3	PF00373
Domain	-	RGPD2 RGPD1 PLEKHN1 CIT SHC3 PLEKHH1 MTMR2 EPB41	3.40e-03	391	118	8	2.30.29.30
Domain	RECEPTOR_TYR_KIN_V_2	EPHA10 EPHB1	3.43e-03	14	118	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA10 EPHB1	3.43e-03	14	118	2	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHA10 EPHB1	3.43e-03	14	118	2	IPR001426
Domain	P_typ_ATPase_c	ATP9A ATP10A	3.43e-03	14	118	2	IPR032630
Domain	P-type_ATPase_N	ATP9A ATP10A	3.43e-03	14	118	2	IPR032631
Domain	EphA2_TM	EPHA10 EPHB1	3.43e-03	14	118	2	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHA10 EPHB1	3.43e-03	14	118	2	IPR001090
Domain	P-type_ATPase_IV	ATP9A ATP10A	3.43e-03	14	118	2	IPR006539
Domain	Eph_TM	EPHA10 EPHB1	3.43e-03	14	118	2	IPR027936
Domain	PLAC	ADAMTS10 ADAMTS6	3.43e-03	14	118	2	PF08686
Domain	EPH_lbd	EPHA10 EPHB1	3.43e-03	14	118	2	SM00615
Domain	Ephrin_lbd	EPHA10 EPHB1	3.43e-03	14	118	2	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHA10 EPHB1	3.43e-03	14	118	2	IPR016257
Domain	EPH_LBD	EPHA10 EPHB1	3.43e-03	14	118	2	PS51550
Domain	PhoLip_ATPase_C	ATP9A ATP10A	3.43e-03	14	118	2	PF16212
Domain	PhoLip_ATPase_N	ATP9A ATP10A	3.43e-03	14	118	2	PF16209
Domain	ZINC_PROTEASE	ECE1 ADAMTS10 ADAMTS6 ECEL1	3.46e-03	98	118	4	PS00142
Domain	FERM_central	PLEKHH1 MYO15A EPB41	3.67e-03	49	118	3	IPR019748
Domain	FERM_domain	PLEKHH1 MYO15A EPB41	3.67e-03	49	118	3	IPR000299
Domain	KAZAL_2	SLCO1B3 SLCO1B7 SLCO4C1	3.88e-03	50	118	3	PS51465
Domain	FERM_1	PLEKHH1 MYO15A EPB41	3.88e-03	50	118	3	PS00660
Domain	FERM_2	PLEKHH1 MYO15A EPB41	3.88e-03	50	118	3	PS00661
Domain	FERM_3	PLEKHH1 MYO15A EPB41	3.88e-03	50	118	3	PS50057
Domain	Band_41_domain	PLEKHH1 MYO15A EPB41	3.88e-03	50	118	3	IPR019749
Domain	B41	PLEKHH1 MYO15A EPB41	3.88e-03	50	118	3	SM00295
Domain	Kazal_dom	SLCO1B3 SLCO1B7 SLCO4C1	4.11e-03	51	118	3	IPR002350
Domain	DUF1605	DHX40 DHX15	5.06e-03	17	118	2	IPR011709
Domain	OB_NTP_bind	DHX40 DHX15	5.06e-03	17	118	2	PF07717
Domain	Ig-like_fold	GP6 COL6A3 DSCAM GBE1 MDGA2 CAMTA2 IL18R1 IL1RAPL2 ROS1 EPHA10 EPHB1	5.11e-03	706	118	11	IPR013783
Domain	7TM_GPCR_Srsx	HTR2C GPR50 SSTR1 ADRA1A	5.57e-03	112	118	4	SM01381
Domain	PH_dom-like	RGPD2 RGPD1 PLEKHN1 CIT SHC3 PLEKHH1 MTMR2 EPB41	5.67e-03	426	118	8	IPR011993
Domain	HA2	DHX40 DHX15	5.67e-03	18	118	2	SM00847
Domain	HA2	DHX40 DHX15	5.67e-03	18	118	2	PF04408
Domain	Helicase-assoc_dom	DHX40 DHX15	5.67e-03	18	118	2	IPR007502
Domain	PLAC	ADAMTS10 ADAMTS6	6.31e-03	19	118	2	PS50900
Domain	PLAC	ADAMTS10 ADAMTS6	6.31e-03	19	118	2	IPR010909
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD2 RGPD1 UBE2I	3.57e-06	9	123	3	28877029
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD2 RGPD1 UBE2I	5.09e-06	10	123	3	27160050
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MED20 RPL38 DHX40 NOL10 ATP9A CIT DDX10 SHKBP1 NSUN5 TMEM161A ARRB1 PNPLA6 UTP25 EIF2S2 OS9 MED12 EPB41 ARMC8	5.58e-06	1497	123	18	31527615
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL38 PMPCB DHX40 NOL10 DDX10 DHX15 USP5 NSUN5 CS PNPLA6 EIF2S2 ASPM PRKDC NUP93 ALDH9A1 ALDOA MED12	5.88e-06	1353	123	17	29467282
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD2 RGPD1 UBE2I	6.98e-06	11	123	3	34110283
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	INPP4A CAMK2A ATP9A NT5DC3 CIT DHX15 USP31 USP5 CS PNPLA6 EIF2S2 MTMR2 USP4 ALDOA ALDOC CNOT1 ARMC8	1.22e-05	1431	123	17	37142655
Pubmed	ASPM and citron kinase co-localize to the midbody ring during cytokinesis.	CIT ASPM	1.24e-05	2	123	2	17534152
Pubmed	Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A.	ALDOA ALDOC	1.24e-05	2	123	2	3009179
Pubmed	Molecular analysis of 23 Pakistani families with autosomal recessive primary microcephaly using targeted next-generation sequencing.	ASPM WDR62	1.24e-05	2	123	2	27784895
Pubmed	MED12 exon 2 and TERT promoter mutations in primary and recurrent breast fibroepithelial lesions.	TERT MED12	1.24e-05	2	123	2	34597441
Pubmed	Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.	SLCO1B3 SLCO4C1	1.24e-05	2	123	2	14993604
Pubmed	TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.	TERT MED12	1.24e-05	2	123	2	26355235
Pubmed	EPB41 suppresses the Wnt/β-catenin signaling in non-small cell lung cancer by sponging ALDOC.	ALDOC EPB41	1.24e-05	2	123	2	33242559
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	1.24e-05	2	123	2	27779234
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RGPD2 GAPVD1 RGPD1 DHX15 ARRB1 PER3 UBE2I WRAP73 ASPM SMARCD1 PRKDC VPS28 NUP93 CNOT1 WDR62	1.48e-05	1155	123	15	20360068
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DHX40 TERT DHX15 SLIT2 ASPM HERC1 DNAH5	2.09e-05	234	123	7	36243803
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GAPVD1 RPL38 NOL10 DDX10 DHX15 USP5 UTP25 PRKDC NUP93 CNOT1 MED12	2.17e-05	653	123	11	22586326
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 MFAP2 ADAMTS6	3.39e-05	18	123	3	35503090
Pubmed	Coordinated metabolic responses to cyclophilin D deletion in the developing heart.	ATP5F1E CS ATP5F1EP2	3.39e-05	18	123	3	38414851
Pubmed	Mode of interactions of human aldolase isozymes with cytoskeletons.	ALDOA ALDOC	3.71e-05	3	123	2	9244396
Pubmed	Aldolase positively regulates of the canonical Wnt signaling pathway.	ALDOA ALDOC	3.71e-05	3	123	2	24993527
Pubmed	G6PC3, ALDOA and CS induction accompanies mir-122 down-regulation in the mechanical asphyxia and can serve as hypoxia biomarkers.	CS ALDOA	3.71e-05	3	123	2	27793029
Pubmed	Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	18296417
Pubmed	Cloning, characterization and mapping of the human ATP5E gene, identification of pseudogene ATP5EP1, and definition of the ATP5E motif.	ATP5F1E ATP5F1EP2	3.71e-05	3	123	2	10727396
Pubmed	DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase.	TERT PRKDC	3.71e-05	3	123	2	15190070
Pubmed	Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.	TERT ROS1	3.71e-05	3	123	2	27153396
Pubmed	Hippocampal transcriptional and neurogenic changes evoked by combination yohimbine and imipramine treatment.	HTR2C SSTR1	3.71e-05	3	123	2	25784603
Pubmed	Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	18492796
Pubmed	Differential Expression of OATP1B3 Mediates Unconjugated Testosterone Influx.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	28389619
Pubmed	Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	23986199
Pubmed	Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	20949553
Pubmed	Cell-free mRNA concentrations of CRH, PLAC1, and selectin-P are increased in the plasma of pregnant women with preeclampsia.	SELP PLAC1	3.71e-05	3	123	2	17554801
Pubmed	MED12, TERT promoter and RBM15 mutations in primary and recurrent phyllodes tumours.	TERT MED12	3.71e-05	3	123	2	29315289
Pubmed	Synergistic interaction between genetics and disease on pravastatin disposition.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	24613363
Pubmed	Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1).	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	10833452
Pubmed	Interaction Between Sex and Organic Anion-Transporting Polypeptide 1b2 on the Pharmacokinetics of Regorafenib and Its Metabolites Regorafenib-N-Oxide and Regorafenib-Glucuronide in Mice.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	30955241
Pubmed	Influence of drug formulation on OATP1B-mediated transport of paclitaxel.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	24755470
Pubmed	OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	29337310
Pubmed	Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.	PRKDC ALDOA	3.71e-05	3	123	2	29084207
Pubmed	Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	31967785
Pubmed	E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model.	SELP PRKDC	3.71e-05	3	123	2	23922938
Pubmed	Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments.	ALDOA ALDOC	3.71e-05	3	123	2	6696436
Pubmed	Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	18413659
Pubmed	Phospholipase D2 directly interacts with aldolase via Its PH domain.	ALDOA ALDOC	3.71e-05	3	123	2	11876650
Pubmed	Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2.	SLCO1B3 SLCO1B7	3.71e-05	3	123	2	19400585
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAPVD1 PMPCB DHX40 SHKBP1 USP5 EIF2S2 MTMR2 OS9 PRKDC NGLY1 NUP93 ALDH9A1 ARMC8	4.32e-05	974	123	13	28675297
Pubmed	Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.	SLCO1B3 SLCO1B7	7.41e-05	4	123	2	22294745
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B3 SLCO1B7	7.41e-05	4	123	2	20644253
Pubmed	EGFR trans-activation by urotensin II receptor is mediated by β-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy.	UTS2R ARRB1	7.41e-05	4	123	2	21369867
Pubmed	Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2.	SLCO1B3 SLCO1B7	7.41e-05	4	123	2	25280775
Pubmed	A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.	HTR2C ARRB1	7.41e-05	4	123	2	16319069
Pubmed	DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.	TERT PRKDC	7.41e-05	4	123	2	17145779
Pubmed	Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling.	ECE1 ARRB1	7.41e-05	4	123	2	19531493
Pubmed	The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by β-Arrestin1 binding with P300-Sp1 to regulate hTERT transcription.	TERT ARRB1	7.41e-05	4	123	2	28425985
Pubmed	Endothelin-converting enzyme 1 and β-arrestins exert spatiotemporal control of substance P-induced inflammatory signals.	ECE1 ARRB1	7.41e-05	4	123	2	24898255
Pubmed	Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.	ALDOA ALDOC	7.41e-05	4	123	2	11399750
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B3 SLCO1B7	7.41e-05	4	123	2	27777271
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MED20 RPP21 ECE1 DHX15 USP5 CS RFLNB TTLL6 RIPOR1 ROS1 NUP93	7.91e-05	754	123	11	35906200
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B3 SLCO1B7	1.23e-04	5	123	2	24194565
Pubmed	Multiple members of a third subfamily of P-type ATPases identified by genomic sequences and ESTs.	ATP9A ATP10A	1.23e-04	5	123	2	9548971
Pubmed	Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.	HTR2C ARRB1	1.23e-04	5	123	2	18768750
Pubmed	Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations.	ALDOA ALDOC	1.23e-04	5	123	2	3674018
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD2 GAPVD1 RPL38 INPP4A RGPD1 CNOT1 MED12 WDR62	1.26e-04	418	123	8	34709266
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	GBE1 DHX15 USP5 SMARCD1 PRKDC MED12	1.37e-04	220	123	6	35785414
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	MED20 GBE1 CIT DHX15 NSUN5 UBE2I EIF2S2 SMARCD1 PRKDC NUP93 ALDOA CNOT1 MED12	1.50e-04	1103	123	13	34189442
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GAPVD1 RPL38 PMPCB NOL10 DDX10 DHX15 CS EIF2S2 PRKDC NUP93 ALDOA ALDOC DNAH5 CNOT1 ARMC8	1.58e-04	1425	123	15	30948266
Pubmed	The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development.	PLEKHH1 SLIT2 KCNE1	1.63e-04	30	123	3	39366945
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	RPL38 FSIP2 USP5 CS SCN7A ALDH9A1 ALDOA ALDOC ATP5F1EP2	1.72e-04	558	123	9	35063084
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	RGPD2 INPP4A RGPD1 NOL10 IL18R1 TNNI3K UBR3 ECEL1	1.84e-04	442	123	8	15815621
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B3 SLCO1B7	1.84e-04	6	123	2	22232210
Pubmed	MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission.	UBE2I MUL1	1.84e-04	6	123	2	19407830
Pubmed	Analysis of DNA methylation and histone modification profiles of liver-specific transporters.	SLCO1B3 SLCO1B7	1.84e-04	6	123	2	19047482
Pubmed	Functional activity of serotoninergic and melatoninergic systems expressed in the skin.	HTR2C GPR50	1.84e-04	6	123	2	12767050
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GAPVD1 RPL38 DHX15 USP5 CS UBE2I EIF2S2 MTMR2 RIPOR1 PRKDC HERC1 ALDH9A1 ALDOA ALDOC CNOT1	1.98e-04	1455	123	15	22863883
Pubmed	Human and mouse proteases: a comparative genomic approach.	MED20 USP31 USP5 USP4	2.01e-04	81	123	4	12838346
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	HTR2C SSTR1 ADAMTS6 MTMR2	2.31e-04	84	123	4	15123239
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	GBE1 USP5 UTP25 USP4 PRKDC ALDOA ALDOC	2.32e-04	344	123	7	30333137
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DHX40 DDX10 SHKBP1 USP5 CS WRAP73 USP4 NUP93 ALDH9A1 ALDOA CNOT1 ARMC8	2.42e-04	1005	123	12	19615732
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PMPCB SOCS6 ECE1 PLEKHN1 USP31 EVA1C USP5 TMEM161A PNPLA6 HERC1	2.47e-04	719	123	10	35337019
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD2 RGPD1	2.58e-04	7	123	2	9037092
Pubmed	β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR.	ACKR4 ARRB1	2.58e-04	7	123	2	23341447
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD2 RGPD1	2.58e-04	7	123	2	15710750
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD2 RGPD1	2.58e-04	7	123	2	11353387
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD2 RGPD1	2.58e-04	7	123	2	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD2 RGPD1	2.58e-04	7	123	2	38838144
Pubmed	The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells.	EIF2S2 PRKDC	2.58e-04	7	123	2	11739746
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD2 RGPD1	2.58e-04	7	123	2	7559465
Pubmed	The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization.	GPR50 ARRB1	2.58e-04	7	123	2	16778767
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD2 RGPD1	2.58e-04	7	123	2	17372272
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD2 RGPD1	2.58e-04	7	123	2	38657106
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD2 RGPD1	2.58e-04	7	123	2	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD2 RGPD1	2.58e-04	7	123	2	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD2 RGPD1	2.58e-04	7	123	2	25187515
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD2 RGPD1	2.58e-04	7	123	2	8603673
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD2 RGPD1	2.58e-04	7	123	2	26632511
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD2 RGPD1	2.58e-04	7	123	2	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD2 RGPD1	2.58e-04	7	123	2	23818861
Pubmed	DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45.	EIF2S2 PRKDC	2.58e-04	7	123	2	9442054
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD2 RGPD1	2.58e-04	7	123	2	23536549
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD2 RGPD1	2.58e-04	7	123	2	12191015
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PLEKHH1 MYO15A EPB41	1.36e-03	50	79	3	1293
GeneFamily	Immunoglobulin like domain containing	GP6 DSCAM MDGA2 IL18R1 IL1RAPL2	1.57e-03	193	79	5	594
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA10 EPHB1	1.66e-03	14	79	2	1095
GeneFamily	Ubiquitin specific peptidases	USP31 USP5 USP4	1.88e-03	56	79	3	366
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL18R1 IL1RAPL2	1.91e-03	15	79	2	1296
GeneFamily	ATPase phospholipid transporting	ATP9A ATP10A	1.91e-03	15	79	2	1210
GeneFamily	DEAH-box helicases	DHX40 DHX15	2.17e-03	16	79	2	500
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS6	3.07e-03	19	79	2	50
GeneFamily	Fibronectin type III domain containing	DSCAM ROS1 EPHA10 EPHB1	5.31e-03	160	79	4	555
ToppCell	control-unassigned\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MED20 SOCS6 PIK3R6 SLCO4C1 UBR3 NUP93 EPB41	1.37e-06	199	123	7	5db7c8089172ac8e796613b3cef618d87007a0ab
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SELP UTS2R HTR2C CIT CRHR2 SCN7A	3.15e-06	145	123	6	78f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 MDGA2 ECE1 MFAP2 MEGF6 EPHB1	9.27e-06	175	123	6	2e54961846c65b185d9bd6e305dd81205579d890
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLCO1B3 MDGA2 CIT RFLNB MEGF6 ASPM	9.27e-06	175	123	6	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 MDGA2 ECE1 MFAP2 MEGF6 EPHB1	9.27e-06	175	123	6	efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KLHL6 SELP ECE1 EVA1C RFLNB MEGF6	1.39e-05	188	123	6	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	SELP UTS2R ADAMTS10 SLIT2 MEGF6 SCN7A	1.39e-05	188	123	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IL18R1 ATP10A PIK3R6 KCNE1 HDC	1.43e-05	189	123	6	7ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell	P15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KLHL6 SELP ECE1 RFLNB MEGF6 HDC	1.48e-05	190	123	6	d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCell	P03-Endothelial-large_vessel_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KLHL6 ECE1 EVA1C RFLNB MEGF6 ALDOC	1.52e-05	191	123	6	b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLAC1 COL6A3 SLITRK4 OTOP2 SLIT2 SCN7A	1.62e-05	193	123	6	e5016959f24370579a8770787e96869f264cf7b3
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KLHL6 SELP ECE1 RFLNB MEGF6 HDC	1.62e-05	193	123	6	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP SLCO1B3 EVA1C ARRB1 ADAMTS6 EPHB1	1.62e-05	193	123	6	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tmem163_Arhgap25\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GLIPR1 NPSR1 PIK3R6 IL1RAPL2 RAVER2	1.85e-05	117	123	5	e1a14b8413a6f4b194217a90eb2c5f95ab14522e
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	INSL5 PLEKHN1 SHKBP1 MEGF6 ECEL1	2.64e-05	126	123	5	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|healthy_donor / Disease condition, Lineage, Cell class and subclass	COL6A3 ADRA1A LAMP3 DNAH5 ATP5F1EP2	4.08e-05	138	123	5	97f5dc17522462133e582b508ad0ef036e656872
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ecel1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	UTS2R GPR50 LAMP3 ECEL1	5.00e-05	73	123	4	857efa05fc1b86d0aa2636321cb5ee1faa171a63
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ecel1-Inhibitory_Gad1Gad2_Htr3a.Ecel1_(Interneuron,__(candidate_CGE-derived_6))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	UTS2R GPR50 LAMP3 ECEL1	5.00e-05	73	123	4	0e4f7b850a211cfe0e5ba3be64105ef6b8ce64e1
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ecel1-Inhibitory_Gad1Gad2_Htr3a.Ecel1_(Interneuron,__(candidate_CGE-derived_6))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	UTS2R GPR50 LAMP3 ECEL1	5.00e-05	73	123	4	9c76e895eb526b3450a906e1db68be17740dbb7b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SSTR1 CRHR2 TNNI3K IL1RAPL2 ECEL1	5.69e-05	148	123	5	4d43efee96a6493abd78e9ca41aab73db0c80626
ToppCell	Myeloid-Myeloid-E_(Neutrophils)\|Myeloid / shred on cell class and cell subclass (v4)	GLIPR1 COL6A3 SLCO4C1 RFLNB HDC	6.07e-05	150	123	5	1bffb8d86b737ac43be902d9468041aef3542f1f
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GLIPR1 OTOP2 TERT IL1RAPL2	6.17e-05	77	123	4	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PER3 SLCO4C1 LAMP3 ROS1 DNAH5	7.09e-05	155	123	5	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UTS2R HTR2C CIT CRHR2 SCN7A	7.09e-05	155	123	5	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SELP MAGEE1 SLCO4C1 ATP5F1EP2 WDR62	7.53e-05	157	123	5	542944030cd9b3f3559e64f9f6598694d74003c0
ToppCell	droplet-Lung-30m-Hematologic-myeloid-neutrophil\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DSCAM GBE1 RFLNB DNAH5 HDC	8.73e-05	162	123	5	9c9a63adb692651ea5a52cc77b02c5ce11d0ccea
ToppCell	droplet-Lung-30m-Hematologic-myeloid-neutrophil-neutrophil\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DSCAM GBE1 RFLNB DNAH5 HDC	8.73e-05	162	123	5	1d29983b22f963b34e72cfd1eec328d2d7c4932f
ToppCell	Fetal_29-31_weeks-Immune-mast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KLHL6 SELP GP6 IL18R1 HDC	8.98e-05	163	123	5	03b2ec226adffba3ce893f3d12e549c841e662fd
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	COL6A3 HTR2C CIT SCN7A ALDOC	9.52e-05	165	123	5	c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 TERT IL18R1 ATP10A SCN7A	9.79e-05	166	123	5	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 TERT IL18R1 ATP10A SCN7A	9.79e-05	166	123	5	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOCS6 NSUN5 UTP25 MYO15A WDR62	1.04e-04	168	123	5	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBE1 ZDHHC17 ATP9A CS UBR3	1.04e-04	168	123	5	de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP ECE1 MFAP2 RFLNB MEGF6	1.06e-04	169	123	5	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP ECE1 MFAP2 RFLNB MEGF6	1.06e-04	169	123	5	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MDGA2 ATP10A ADRA1A ADAMTS6 ECEL1	1.09e-04	170	123	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MDGA2 ATP10A ADRA1A ADAMTS6 ECEL1	1.09e-04	170	123	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MDGA2 ATP10A ADRA1A ADAMTS6 ECEL1	1.09e-04	170	123	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GLIPR1 INPP4A IL18R1 ATP10A EPHB1	1.13e-04	171	123	5	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IL18R1 ATP10A PIK3R6 HDC	1.16e-04	172	123	5	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR162 SLIT2 RAVER2 ALDOC MED12	1.16e-04	172	123	5	e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 IL18R1 OS9 HERC1 HDC	1.16e-04	172	123	5	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IL18R1 ATP10A PIK3R6 HDC	1.16e-04	172	123	5	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 IL18R1 OS9 HERC1 HDC	1.16e-04	172	123	5	953b05f776348cff784e79c93df65841939d880f
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NPSR1 ECE1 SCN7A RIPOR1 EPHB1	1.22e-04	174	123	5	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	INPP4A MYO1H BCKDHA MED12 ATP5F1EP2	1.22e-04	174	123	5	a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UTS2R HTR2C CIT CRHR2 SCN7A	1.22e-04	174	123	5	a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCell	CV-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	GBE1 PIK3R6 ALDOA ALDOC WDR62	1.22e-04	174	123	5	26544cc5f51cb4dc1251e62d9f80b6c956194d38
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SHC3 SLIT2 ADRA1A LINC01553	1.25e-04	175	123	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SSTR1 ADRA1A ADAMTS6 SCN7A ALDOC	1.32e-04	177	123	5	fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5DC3 TERT ECEL1 EPHA10 WDR62	1.32e-04	177	123	5	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS10 ARRB1 RFLNB UTP25 PRKDC	1.36e-04	178	123	5	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SESTD1 DSCAM PLEKHN1 CIT ECEL1	1.39e-04	179	123	5	4f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCell	CV-Healthy-2\|CV / Virus stimulation, Condition and Cluster	ATP5F1E RPL38 CIT ASPM LAMP3	1.43e-04	180	123	5	e182e5c495dd82d4fcbf1a920086c70b064801f3
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM SSTR1 ECE1 CRHR2 PER3	1.43e-04	180	123	5	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP ECE1 ACKR4 MEGF6 TTLL6	1.47e-04	181	123	5	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SSTR1 CRHR2 TNNI3K ECEL1	1.51e-04	97	123	4	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDGA2 ROS1 MYO15A DNAH5 EPHA10	1.58e-04	184	123	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GBE1 SLCO1B3 IL18R1 USP31 EVA1C	1.58e-04	184	123	5	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRHR2 SLIT2 IL1RAPL2 RAVER2 SCN7A	1.58e-04	184	123	5	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDGA2 ROS1 MYO15A DNAH5 EPHA10	1.58e-04	184	123	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDGA2 ROS1 MYO15A DNAH5 EPHA10	1.58e-04	184	123	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CIT SHC3 IL1RAPL2 ROS1 DNAH5	1.67e-04	186	123	5	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KLHL6 SELP ECE1 RFLNB HDC	1.67e-04	186	123	5	153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP EVA1C ARRB1 ADAMTS6 EPHB1	1.67e-04	186	123	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MDGA2 IL18R1 ATP10A EVA1C ADAMTS6	1.75e-04	188	123	5	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SHC3 SLCO4C1 MEGF6 LAMP3 ROS1	1.80e-04	189	123	5	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP IL18R1 ADAMTS6 RIPOR1 MED12	1.80e-04	189	123	5	bccb3481ffed597c845fe860da658505316105b5
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 MDGA2 USP31 PIK3R6 EPHB1	1.80e-04	189	123	5	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	KLHL6 SLCO1B3 MEGF6 ASPM	1.84e-04	102	123	4	2c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ECE1 EVA1C RFLNB MEGF6 HDC	1.84e-04	190	123	5	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SELP ECE1 IL18R1 EVA1C ADAMTS6	1.84e-04	190	123	5	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	droplet-Marrow-nan-21m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIPR1 BCKDHA SOCS6 NUP93 ALDH9A1	1.84e-04	190	123	5	6c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C ADRA1A ADAMTS6 SCN7A ALDOC	1.88e-04	191	123	5	764c3a8829ae1253a0790744138266e81fc075ec
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 ACKR4 SLIT2 MFAP2 SCN7A	1.88e-04	191	123	5	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 MDGA2 ECE1 ATP10A ADRA1A	1.88e-04	191	123	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SESTD1 COL6A3 IL18R1 SLIT2 SCN7A	1.88e-04	191	123	5	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL6A3 ACKR4 SLIT2 MFAP2 SCN7A	1.88e-04	191	123	5	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL6 IL18R1 ATP10A PIK3R6 HDC	1.88e-04	191	123	5	468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HTR2C GPR50 EVA1C ECEL1	1.91e-04	103	123	4	d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP SLCO1B3 EVA1C ADAMTS6 EPHB1	1.93e-04	192	123	5	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	SESTD1 COL6A3 ECE1 SLIT2 SCN7A	1.93e-04	192	123	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 USP31 PIK3R6 RFLNB EPHB1	1.93e-04	192	123	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLCO4C1 MEGF6 LAMP3 ROS1 DNAH5	1.93e-04	192	123	5	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP SLCO1B3 EVA1C ADAMTS6 EPHB1	1.93e-04	192	123	5	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELP EVA1C ARRB1 ADAMTS6 EPHB1	1.93e-04	192	123	5	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ACKR4 SLIT2 MFAP2 SCN7A	1.93e-04	192	123	5	20ede290e01ad574afd122d72b59dbc52c595fad
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ACKR4 SLIT2 MFAP2 SCN7A	1.98e-04	193	123	5	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 ACKR4 SLIT2 MFAP2 SCN7A	1.98e-04	193	123	5	96c85b250d04b5f400512097d925061c6dc2906b
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL6A3 CAMK2A SLIT2 ADRA1A SCN7A	1.98e-04	193	123	5	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	SESTD1 COL6A3 ECE1 SLIT2 SCN7A	1.98e-04	193	123	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLIPR1 COL6A3 SLIT2 MFAP2 SCN7A	2.03e-04	194	123	5	e2db75f4de114631b8bda4e188f84446545538b7
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	SESTD1 COL6A3 ECE1 SLIT2 SCN7A	2.03e-04	194	123	5	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	SESTD1 COL6A3 ECE1 SLIT2 SCN7A	2.03e-04	194	123	5	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	SELP SSTR1 ECE1 EVA1C ADAMTS6	2.03e-04	194	123	5	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELP SSTR1 ECE1 EVA1C ADAMTS6	2.03e-04	194	123	5	fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	SESTD1 COL6A3 ECE1 SLIT2 SCN7A	2.03e-04	194	123	5	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	Differ-Basal\|World / shred by cell class for mouse tongue	GPR50 OTOP2 ALDOA ALDOC HDC	2.03e-04	194	123	5	851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	COL6A3 SLIT2 MFAP2 ADRA1A SCN7A	2.07e-04	195	123	5	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLCO1B3 USP31 EVA1C RFLNB RIPOR1	2.07e-04	195	123	5	56efeb58df19f357d7d5ce87348d4f196a595421
Drug	acetyldithio-CoA	CS ALDOA ALDOC	2.97e-06	6	122	3	CID003082679
Disease	worry measurement	GAPVD1 DSCAM MYO1H FBXL17 ECE1 UTP25 MTMR2	3.73e-06	154	122	7	EFO_0009589
Disease	mitochondrial complex V (ATP synthase) deficiency nuclear type 3 (implicated_via_orthology)	ATP5F1E ATP5F1EP2	1.70e-05	2	122	2	DOID:0060332 (implicated_via_orthology)
Disease	Seasonal Affective Disorder	HTR2C GPR50 PER3	3.71e-05	16	122	3	C0085159
Disease	Autosomal Recessive Primary Microcephaly	CIT ASPM WDR62	1.00e-04	22	122	3	C3711387
Disease	Primary microcephaly	CIT ASPM WDR62	1.00e-04	22	122	3	C0431350
Disease	Unipolar Depression	SELP HTR2C CAMK2A TERT ADRA1A ARRB1 MED12	1.05e-04	259	122	7	C0041696
Disease	bilirubin metabolic disorder (implicated_via_orthology)	SLCO1B3 SLCO1B7	1.68e-04	5	122	2	DOID:2741 (implicated_via_orthology)
Disease	Depressive disorder	SELP HTR2C CAMK2A NPSR1 CRHR2 PER3 MED12	2.06e-04	289	122	7	C0011581
Disease	Hirschsprung Disease	ECE1 UTP25 MED12	2.85e-04	31	122	3	C0019569
Disease	Lung diseases	TERT CRHR2 PRKDC DNAH5	3.13e-04	78	122	4	C0024115
Disease	microcephaly (implicated_via_orthology)	CIT ASPM WDR62	3.13e-04	32	122	3	DOID:10907 (implicated_via_orthology)
Disease	blindness (implicated_via_orthology)	PNPLA6 MYO15A	4.67e-04	8	122	2	DOID:1432 (implicated_via_orthology)
Disease	Major Depressive Disorder	HTR2C CAMK2A TERT ADRA1A ARRB1 MED12	5.35e-04	243	122	6	C1269683
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B3 SLCO1B7	5.99e-04	9	122	2	EFO_0800562
Disease	congestive heart failure (implicated_via_orthology)	ECE1 CS ARRB1	6.55e-04	41	122	3	DOID:6000 (implicated_via_orthology)
Disease	Mental Depression	HTR2C CAMK2A NPSR1 CRHR2 PER3 MED12	6.74e-04	254	122	6	C0011570
Disease	colitis (biomarker_via_orthology)	SELP CRHR2 ARRB1	7.04e-04	42	122	3	DOID:0060180 (biomarker_via_orthology)
Disease	Uterine leiomyoma, estrogen-receptor negative breast cancer	TERT DDX10	7.47e-04	10	122	2	EFO_1000650, HP_0000131
Disease	Gastric Adenocarcinoma	ROS1 EPHA10 EPHB1	8.62e-04	45	122	3	C0278701
Disease	gastrointestinal stromal tumor (is_implicated_in)	SLCO1B3 TERT	9.10e-04	11	122	2	DOID:9253 (is_implicated_in)
Disease	congestive heart failure (biomarker_via_orthology)	SELP ECE1 CS KCNE1	1.03e-03	107	122	4	DOID:6000 (biomarker_via_orthology)
Disease	urate measurement, bone density	GLIPR1 DSCAM PMPCB GBE1 SHC3 DDX10 FSIP2 PRKDC EPHB1	1.11e-03	619	122	9	EFO_0003923, EFO_0004531
Disease	alcohol and nicotine codependence	RGPD2 RGPD1	1.28e-03	13	122	2	EFO_0004776
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B3 SLCO1B7	1.28e-03	13	122	2	EFO_0800474
Disease	intraocular pressure measurement	COL6A3 OTOP2 FBXL17 DRAM2 CAMTA2 EVA1C ADAMTS6 ALDH9A1	1.29e-03	509	122	8	EFO_0004695
Disease	Hepatomegaly	DSCAM CAMK2A HDC	1.47e-03	54	122	3	C0019209
Disease	Kartagener syndrome (implicated_via_orthology)	SLIT2 DNAH5	1.49e-03	14	122	2	DOID:0050144 (implicated_via_orthology)
Disease	central nervous system cancer, glioblastoma multiforme	TERT RAVER2	1.49e-03	14	122	2	EFO_0000326, EFO_0000519
Disease	bipolar disorder, response to lithium ion	SESTD1 LAMP3	1.49e-03	14	122	2	GO_0010226, MONDO_0004985
Disease	Malignant neoplasm of breast	UTS2R MAGEE1 TERT DDX10 TMEM161A ADRA1A PER3 IL1RAPL2 EIF2S2 SMARCD1 ALDOA MED12	1.68e-03	1074	122	12	C0006142
Disease	Aganglionosis, Colonic	ECE1 UTP25	1.72e-03	15	122	2	C0085758
Disease	Autosomal recessive primary microcephaly	ASPM WDR62	1.72e-03	15	122	2	cv:C3711387
Disease	Aganglionosis, Rectosigmoid Colon	ECE1 UTP25	1.72e-03	15	122	2	C1257840
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	GAPVD1 FBXL17 GBE1 MDGA2 SHC3 SLIT2 TNNI3K PRKDC HERC1 EPHB1	1.85e-03	801	122	10	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Cocaine Abuse	HTR2C CAMK2A CRHR2 ADRA1A	1.94e-03	127	122	4	C0009171
Disease	primary autosomal recessive microcephaly (is_implicated_in)	ASPM WDR62	1.96e-03	16	122	2	DOID:0070296 (is_implicated_in)
Disease	Glycogen storage disease	GBE1 ALDOA	2.21e-03	17	122	2	cv:C0017919
Disease	Congenital Intestinal Aganglionosis	ECE1 UTP25	2.21e-03	17	122	2	C3661523
Disease	X-21441 measurement	SLCO1B3 SLCO1B7	2.21e-03	17	122	2	EFO_0800814
Disease	Adrenocortical carcinoma	TERT MED12	2.48e-03	18	122	2	C0206686
Disease	neuroticism measurement, cognitive function measurement	DSCAM MYO1H FBXL17 GBE1 ECE1 MTMR2 USP4 EPHB1	2.49e-03	566	122	8	EFO_0007660, EFO_0008354
Disease	primary ciliary dyskinesia (implicated_via_orthology)	SLIT2 DNAH5	2.77e-03	19	122	2	DOID:9562 (implicated_via_orthology)
Disease	aggressive behaviour measurement, ADHD symptom measurement	MYO1H FBXL17 MDGA2	2.84e-03	68	122	3	EFO_0007826, EFO_0007860
Disease	selenium measurement, response to dietary selenium supplementation	LRRC8B DNAH5	3.07e-03	20	122	2	EFO_0006331, EFO_0600021
Disease	chemokine (C-C motif) ligand 27 measurement	SLCO1B3 SLCO1B7 USP31	3.09e-03	70	122	3	EFO_0008082
Disease	amyloid-beta measurement	DSCAM NPSR1 NOL10 EVA1C OS9 PRKDC	3.65e-03	355	122	6	EFO_0005194
Disease	glioma	TERT RAVER2	3.71e-03	22	122	2	EFO_0005543
Disease	otitis media (implicated_via_orthology)	RPL38 DNAH5	3.71e-03	22	122	2	DOID:10754 (implicated_via_orthology)
Disease	Bipolar Disorder	HTR2C GPR50 DSCAM CAMK2A CRHR2 ADRA1A PER3	3.76e-03	477	122	7	C0005586

Protein segments in the cluster

Peptide	Gene	Start	Entry
TRYYLCLQLRQDIVA	EPB41	301	P11171
RVTIEYYSQLKTVCV	ALDH9A1	471	P49189
RCQYVTEKVLAAVYK	ALDOC	201	P09972
LVMYCRVYVVAKRES	ADRA1A	201	P35348
RCQYVTEKVLAAVYK	ALDOA	201	P04075
VQDRYYLCVSVTKKE	EXOC1L	31	A0A1B0GW35
VITYCLTIYVLRRQA	HTR2C	231	P28335
QEVAAAVIQRCYRKY	CAMTA2	1071	O94983
YVACTYQRVDCVKKL	ASB11	201	Q8WXH4
SYIRYSQICAKAVRD	ATP5F1E	11	P56381
TSRDYYINIRKALVT	DHX15	681	O43143
VILRYNENLSKYCIR	CIT	1711	O14578
TCLQAAYRGYKVRQL	ASPM	1806	Q8IZT6
KAAIVIQVRCRAYYQ	ASPM	2141	Q8IZT6
EYLKERRVYVTLTCA	ARRB1	46	P49407
SYIRYSQICAKVVRD	ATP5F1EP2	11	Q5VTU8
AALVYAARAYNCVLV	ATP10A	701	O60312
TAVLITRYDICIYKN	ADAMTS10	341	Q9H324
DNAVLITRYDICTYK	ADAMTS6	351	Q9UKP5
YKRAVYCIIGRCDVT	NUP93	386	Q8N1F7
YCYVDRNKRTAFVTL	RAVER2	96	Q9HCJ3
TYLSLQYRRDVVFCQ	INPP4A	666	Q96PE3
LYALVCETQRYSAVL	NSUN5	36	Q96P11
YNIVKFCRAIDIIYS	ACKR4	256	Q9NPB9
DYICQYLSTVRERRV	HDC	16	P19113
IVCSRKRAYSKEAVY	EPHB1	561	P54762
NAETIREVCTKYIYN	PMPCB	446	O75439
REVCTKYIYNRSPAI	PMPCB	451	O75439
QLEVVKSSSYCEYLR	PNPLA6	1211	Q8IY17
TVCVIYRVDLVLFYR	IL18R1	346	Q13478
CVNRQRDQVKRYYSV	GLIPR1	206	P48060
AKCINAVSFRDRIYV	KLHL6	506	Q8WZ60
KHVITCRYLSQRYID	MAGEE1	871	Q9HCI5
CYNIVKDRYVRVSNN	NGLY1	496	Q96IV0
CRVVRYLQVVLLYAS	NPSR1	121	Q6W5P4
ERYYARGCQFIVSKI	GPR162	161	Q16538
YSAGCVVRRKVVYLE	MYO15A	2906	Q9UKN7
DKEVANRYFTTVCVR	GAPVD1	1241	Q14C86
KHLSEVYRCVYKVRS	HERC1	1291	Q15751
SRKCYYIFIVETICV	KCNG4	256	Q8TDN1
YERIFSVRNTCIYLV	GPR50	136	Q13585
VCTLRELNKYRQYLT	FSIP2	131	Q5CZC0
ARQYYTKGNLVRICL	GP6	261	Q9HCN6
QINCIDSVIRYLKSY	PER3	536	P56645
NIAAVLCIATIYVRY	DRAM2	61	Q6UX65
VKYNTTRNAYRECLE	CRHR2	71	Q13324
VTAALYSVYRQKARV	MUL1	21	Q969V5
RITKINERYELCDTY	MTMR2	226	Q13614
VYKIRLRCQSSGYQR	LAMP3	401	Q9UQV4
DVYAKYVLRSICQQE	MED12	1276	Q93074
RCYVRDKEVNSQVYS	ATP9A	126	O75110
GACVALVSVRVYYKQ	EPHA10	196	Q5JZY3
LVSVRVYYKQCRATV	EPHA10	201	Q5JZY3
VYYKQCRATVRGLAT	EPHA10	206	Q5JZY3
RVRCYDTYQLSLKFE	NOL10	76	Q9BSC4
LRRYIKEYVTCHTCR	EIF2S2	271	P20042
KAECIVRLYDNFTVY	ECEL1	646	O95672
RYQCVYSLAEIFKVL	LRRC8B	301	Q6P9F7
KEQFYYERTVFLRCV	MDGA2	146	Q7Z553
LEYIRTVIYICASSR	INSL5	31	Q9Y5Q6
TRQALVIYYSFNIVC	OTOP2	321	Q7RTS6
YSALQVLSRRCYGKQ	EVA1C	216	P58658
LLSRSRYTQEYICQI	ARMC8	156	Q8IUR7
VYTLTNRRYLEKCIA	GBE1	461	Q04446
RYTAYRCKQLSDTSI	FBXL17	416	Q9UF56
CVAAKIYRNLYREGS	CS	211	O75390
VAVVCYLRSQVRATY	COL6A3	3056	P12111
SRKYCQNRYTDLVAI	SELP	56	P16109
QARVLESYRSCYVVE	KCNE1	96	P15382
ERAQRCFVSYVRSVY	DDX10	466	Q13206
VSEAERKAQVYYRAC	ECE1	171	P42892
TTKVYARIVCPIRYE	DHX40	676	Q8IX18
VAEKCVDYFQRFRRS	DNAH5	3156	Q8TE73
VCFYSLRRVYVINKE	MFAP2	121	P55001
YAAKRANANRVVICY	BCKDHA	221	P12694
AKKYVCTYLSVQERD	RGPD1	36	P0DJD0
KASKIETRGTRYQYC	MED20	106	Q9H944
YRQVYTTEARTVLRC	MEGF6	96	O75095
YVCEVSNRYGTAKVI	DSCAM	291	O60469
YQFTYRVTECGIRAK	PLAC1	71	Q9HBJ0
ENVLYVNCEKVSVYR	SLITRK4	36	Q8IW52
TCTVLYSKYDAQRLA	UTP25	716	Q68CQ4
YCLTVLSVDRYVAVV	SSTR1	146	P30872
YVVRRCANRQNLYTK	TRIM34	376	Q9BYJ4
LINTIRVVCASYEDY	PLEKHN1	291	Q494U1
VCRYFYSKVQQRRQE	SMARCD1	491	Q96GM5
EAREIQQRVVRVYCY	TMEM161A	356	Q9NX61
VRCSRYLYTLVITDK	RPL38	36	P63173
KYVCTYLSVQERDPR	RGPD2	46	P0DJD1
AVYTTTLDYNCRKTL	RFLNB	176	Q8N5W9
CYNSRIRYLEKSEVT	IL1RAPL2	141	Q9NP60
IEKYICYAEQTRAVL	NT5DC3	271	Q86UY8
TEELYQRIYAFCTRL	PIK3R6	91	Q5UE93
YVAYVAKDPVNRRAC	SHC3	266	Q92529
RFYCYTERTIAKRLV	RPP21	36	Q9H633
IAVAYTQFLVCYRLK	SHKBP1	206	Q8TBC3
KYLASCVQYRLVVRD	WRAP73	21	Q9P2S5
DACTRKSYVYFVIQV	SLCO1B7	481	G3V0H7
SACIAYIRITQYLDA	CAMK2A	426	Q9UQM7
VIVSSKYKQRYECRL	OS9	61	Q13438
EQYTRYQEVCRQRSK	SESTD1	256	Q86VW0
RDVVYNYITEKTTCR	LINC01553	36	A4QN01
TRCLIECRDEYKYNV	CNOT1	1711	A5YKK6
LESLYQAVCDRISRY	USP4	616	Q13107
IYCQNRVEYEKRVRA	UBE2I	136	P63279
VYYNCSCIERKTEIT	SLCO4C1	541	Q6ZQN7
RDNTCTRKFFIYVAI	SLCO1B3	526	Q9NPD5
YTAACSRLLVQYKAA	VPS28	66	Q9UK41
DNGCRITYYILEIRK	ROS1	1776	P08922
ISCRGERIRDYYQKQ	SLIT2	1451	O94813
SSCRYESVRRAAQQY	TTLL6	66	Q8N841
YATYCQRAVERTLRT	PLEKHH1	956	Q9ULM0
EGERYNYSKCTVVVR	PRKDC	1326	P78527
IVKATQYGIYERCRE	ZDHHC17	61	Q8IUH5
KYVAVACQDRNVRVY	WDR62	641	O43379
RTARIVNYLTTCLTY	UTS2R	291	Q9UKP6
QEYTRNVVRYCLEAL	UBR3	596	Q6ZT12
AVSATIIQRAYKNYR	SCN7A	1626	Q01118
EVCTQTAYILFYQRR	USP31	751	Q70CQ4
SKIDELYEAYCVQRR	RIPOR1	141	Q6ZS17
IVAIKRYRANTYCSK	TNNI3K	486	Q59H18
VNYERVREYCLKVLE	TTC9B	151	Q8N6N2
QYLCRFVIRQYTRID	SOCS6	501	O14544
SIIKPQNTYCVRRYA	TERT	731	O14746
QNTYCVRRYAVVQKA	TERT	736	O14746
CLATEKVKYTQRVDY	USP5	471	P45974
EEKGYRQYVLCTLSR	LRRC51	141	Q96E66
IQATYKRCLGRREYV	MYO1H	711	Q8N1T3