Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PCMTD1 PRAMEF1 PRAMEF2 PRAMEF13 RPTOR PRAMEF14	3.51e-05	95	129	6	GO:0140767
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PCMTD1 PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	1.91e-04	82	129	5	GO:1990756
GeneOntologyMolecularFunction	synaptic receptor adaptor activity	SHANK3 SHANK2	2.46e-04	4	129	2	GO:0030160
GeneOntologyMolecularFunction	molecular adaptor activity	ANK3 NUP98 ATG14 KCTD1 PCMTD1 PPP1R13L PRAMEF1 PRAMEF2 PRAMEF13 SHANK3 NLRP6 SHANK2 RACK1 ANAPC1 RPTOR PRAMEF14 CIDEC SUPT7L EIF4G1 HCFC2	4.35e-04	1356	129	20	GO:0060090
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	4.39e-04	55	129	4	GO:0042974
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	ANK3 NUP98 ATG14 KCTD1 PCMTD1 PPP1R13L PRAMEF1 PRAMEF2 PRAMEF13 SHANK3 NLRP6 SHANK2 RACK1 RPTOR PRAMEF14 CIDEC SUPT7L HCFC2	4.78e-04	1160	129	18	GO:0030674
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	CDC20B PCMTD1 PRAMEF1 PRAMEF2 PRAMEF13 ANAPC1 PRAMEF14 DCAF4L1	6.49e-05	212	133	8	GO:0031461
GeneOntologyCellularComponent	ubiquitin ligase complex	CDC20B PCMTD1 PRAMEF1 PRAMEF2 ASB12 PRAMEF13 ANAPC1 PRAMEF14 ABTB1 DCAF4L1	8.71e-05	352	133	10	GO:0000151
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	2.26e-04	47	133	4	GO:0031462
GeneOntologyCellularComponent	transferase complex	CDC20B ATG14 PFKL PCMTD1 PRAMEF1 PRAMEF2 ASB12 PRAMEF13 MAP3K5 PHKA1 ANAPC1 PRAMEF14 SUPT7L ABTB1 HCFC2 DCAF4L1	4.15e-04	963	133	16	GO:1990234
Domain	Ank_2	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	3.47e-09	215	130	13	PF12796
Domain	-	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	1.92e-08	248	130	13	1.25.40.20
Domain	ANK	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	2.22e-08	251	130	13	SM00248
Domain	ANK_REPEAT	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	2.44e-08	253	130	13	PS50088
Domain	Ankyrin_rpt-contain_dom	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	2.55e-08	254	130	13	IPR020683
Domain	ANK_REP_REGION	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	2.55e-08	254	130	13	PS50297
Domain	Ankyrin_rpt	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	3.68e-08	262	130	13	IPR002110
Domain	Ank	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 ANKRD46 ANKRD44 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	6.65e-08	228	130	12	PF00023
Domain	ARM-type_fold	MROH9 ARFGEF1 WDFY4 NCDN UPF2 RPTOR PI4KA MROH2B EIF4G1 EIF3K ULK4 ATM TARBP1	7.16e-07	339	130	13	IPR016024
Domain	LamGL	PAPPA USH2A	2.86e-04	4	130	2	SM00560
Domain	LamG-like	PAPPA USH2A	2.86e-04	4	130	2	IPR006558
Domain	PRAME_family	PRAMEF1 PRAMEF2 PRAMEF13	2.94e-04	19	130	3	IPR026271
Domain	VWF_A	ITGA11 HMCN2 ANAPC1 SEC24B C2	6.41e-04	99	130	5	IPR002035
Domain	-	PRAMEF1 PRAMEF2 PRAMEF13 ADGRA2 NLRC4 NLRP6 LRCH4 ADGRA3	1.85e-03	321	130	8	3.80.10.10
Domain	MIF4G	UPF2 EIF4G1	2.09e-03	10	130	2	SM00543
Domain	MIF4G	UPF2 EIF4G1	2.09e-03	10	130	2	PF02854
Domain	MIF4G-like_typ-3	UPF2 EIF4G1	2.09e-03	10	130	2	IPR003890
Domain	L_dom-like	PRAMEF1 PRAMEF2 PRAMEF13 ADGRA2 NLRC4 NLRP6 LRCH4 ADGRA3	2.11e-03	328	130	8	IPR032675
Domain	WD40	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	2.26e-03	259	130	7	PF00400
Domain	-	SEMA7A CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	2.32e-03	333	130	8	2.130.10.10
Domain	SOCS_box	ASB15 ASB12 ASB9	2.33e-03	38	130	3	PF07525
Domain	WD40/YVTN_repeat-like_dom	SEMA7A CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	2.41e-03	335	130	8	IPR015943
Domain	SOCS_box	ASB15 ASB12 ASB9	2.51e-03	39	130	3	SM00969
Domain	SOCS_box	ASB15 ASB12 ASB9	2.51e-03	39	130	3	IPR001496
Domain	SOCS	ASB15 ASB12 ASB9	2.51e-03	39	130	3	PS50225
Domain	Tyr_kinase_rcpt_2_CS	ROS1 LTK	2.54e-03	11	130	2	IPR002011
Domain	WD40	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	2.74e-03	268	130	7	SM00320
Domain	ARM-like	MROH9 ARFGEF1 WDFY4 RPTOR MROH2B ULK4 TARBP1	2.85e-03	270	130	7	IPR011989
Domain	WD40_repeat	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	2.97e-03	272	130	7	IPR001680
Domain	C8	MUC19 FCGBP	3.03e-03	12	130	2	PF08742
Domain	TIL	MUC19 FCGBP	3.03e-03	12	130	2	PF01826
Domain	RECEPTOR_TYR_KIN_II	ROS1 LTK	3.03e-03	12	130	2	PS00239
Domain	WD_REPEATS_1	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	3.35e-03	278	130	7	PS00678
Domain	WD_REPEATS_2	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	3.42e-03	279	130	7	PS50082
Domain	WD_REPEATS_REGION	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	3.42e-03	279	130	7	PS50294
Domain	Unchr_dom_Cys-rich	MUC19 FCGBP	3.57e-03	13	130	2	IPR014853
Domain	C8	MUC19 FCGBP	3.57e-03	13	130	2	SM00832
Domain	TIL_dom	MUC19 FCGBP	4.14e-03	14	130	2	IPR002919
Domain	-	MROH9 ARFGEF1 WDFY4 RPTOR MROH2B ULK4	4.63e-03	222	130	6	1.25.10.10
Domain	-	UPF2 EIF4G1	4.76e-03	15	130	2	1.25.40.180
Domain	PI3/4_kinase_CS	PI4KA ATM	4.76e-03	15	130	2	IPR018936
Domain	MIF4-like	UPF2 EIF4G1	4.76e-03	15	130	2	IPR016021
Domain	WD40_repeat_dom	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	4.80e-03	297	130	7	IPR017986
Domain	TLC	CLN8 TRAM2	5.41e-03	16	130	2	SM00724
Domain	VWF_type-D	MUC19 FCGBP	5.41e-03	16	130	2	IPR001846
Domain	-	PI4KA ATM	5.41e-03	16	130	2	1.10.1070.11
Domain	VWFD	MUC19 FCGBP	5.41e-03	16	130	2	PS51233
Domain	PI3Kc	PI4KA ATM	5.41e-03	16	130	2	SM00146
Domain	TLC	CLN8 TRAM2	5.41e-03	16	130	2	PS50922
Domain	VWD	MUC19 FCGBP	5.41e-03	16	130	2	SM00216
Domain	TRAM_LAG1_CLN8	CLN8 TRAM2	5.41e-03	16	130	2	PF03798
Domain	TLC-dom	CLN8 TRAM2	5.41e-03	16	130	2	IPR006634
Domain	VWD	MUC19 FCGBP	5.41e-03	16	130	2	PF00094
Domain	WD40_repeat_CS	CDC20B WDFY4 RACK1 HERC1 WDR17	5.83e-03	164	130	5	IPR019775
Domain	PI3_PI4_kinase	PI4KA ATM	6.84e-03	18	130	2	PF00454
Domain	PI3_4_KINASE_1	PI4KA ATM	6.84e-03	18	130	2	PS00915
Domain	PI3_4_KINASE_2	PI4KA ATM	6.84e-03	18	130	2	PS00916
Domain	PI3/4_kinase_cat_dom	PI4KA ATM	6.84e-03	18	130	2	IPR000403
Domain	PI3_4_KINASE_3	PI4KA ATM	6.84e-03	18	130	2	PS50290
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CLN8 EPRS1 ANK3 PFKL ANKRD50 PRAMEF1 PRAMEF2 PRAMEF13 WDFY4 NCDN PAXBP1 RACK1 PI4KA PRAMEF14 HERC1 UTRN MINDY1 DSE	2.04e-07	1084	134	18	11544199
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	6.18e-07	18	134	4	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	6.18e-07	18	134	4	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	6.18e-07	18	134	4	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	6.18e-07	18	134	4	14675769
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	7.81e-07	19	134	4	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	9.73e-07	20	134	4	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	9.73e-07	20	134	4	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	9.73e-07	20	134	4	21425410
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	1.46e-06	22	134	4	31729367
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	EPRS1 TTC28 PFKL ANKRD50 ADCY6 NCDN AIFM2 DNAJC10 UPF2 SLC22A4 SHCBP1 LRCH4 EXOC4	1.51e-06	650	134	13	38777146
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	1.76e-06	23	134	4	19480014
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	EPRS1 ITGA11 GLT1D1 PCMTD1 PRAMEF1 PRAMEF2 PRAMEF13 SHANK3 PI4KA PRAMEF14 NAV3 EXOC4	2.06e-06	564	134	12	21565611
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	2.50e-06	25	134	4	12620990
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	2.50e-06	25	134	4	37451217
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	2.95e-06	26	134	4	18500982
Pubmed	The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.	SHANK3 SHANK2 ROS1	3.09e-06	8	134	3	10958799
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EPRS1 NUP98 ARFGEF1 NCDN RPTOR PI4KA DHCR24 SEC24B EIF4G1 POFUT1 TRAPPC3 ATP2B4 TARBP1 MINDY1 EXOC4	3.79e-06	942	134	15	31073040
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	4.01e-06	28	134	4	25089626
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	5.34e-06	30	134	4	38786026
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	6.97e-06	32	134	4	37889087
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	1.01e-05	35	134	4	19389355
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	EPRS1 ANK3 MYO18A PFKL SHANK3 NCDN SHANK2 RACK1 UPF2 RPTOR PI4KA EIF4G1 PACS2 RAI14 TRAPPC3 UTRN ATP2B4 EXOC4	1.02e-05	1431	134	18	37142655
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	PRAMEF1 MDM2 PRAMEF2 PRAMEF13 LPCAT3 PRAMEF14 LRCH4 UTRN DCAF4L1	1.24e-05	363	134	9	14691545
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ANK3 PAK6 PPP1R13L SHANK2 RACK1 PI4KA SEC24B EIF4G1 RAI14 UTRN ATP2B4	1.28e-05	565	134	11	25468996
Pubmed	Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.	SHANK3 SHANK2	1.47e-05	2	134	2	33126897
Pubmed	ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.	MDM2 ATM	1.47e-05	2	134	2	11331603
Pubmed	Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.	SHANK3 SHANK2	1.47e-05	2	134	2	22699619
Pubmed	Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.	SHANK3 SHANK2	1.47e-05	2	134	2	31052177
Pubmed	Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.	SHANK3 SHANK2	1.47e-05	2	134	2	27199660
Pubmed	Characterization of the Shank family of synaptic proteins. Multiple genes, alternative splicing, and differential expression in brain and development.	SHANK3 SHANK2	1.47e-05	2	134	2	10506216
Pubmed	ATM phosphorylation of Mdm2 Ser394 regulates the amplitude and duration of the DNA damage response in mice.	MDM2 ATM	1.47e-05	2	134	2	22624716
Pubmed	Expression profiles of the autism-related SHANK proteins in the human brain.	SHANK3 SHANK2	1.47e-05	2	134	2	37953224
Pubmed	Shank2/3 double knockout-based screening of cortical subregions links the retrosplenial area to the loss of social memory in autism spectrum disorders.	SHANK3 SHANK2	1.47e-05	2	134	2	36100669
Pubmed	Proline-rich synapse-associated protein-1 and 2 (ProSAP1/Shank2 and ProSAP2/Shank3)-scaffolding proteins are also present in postsynaptic specializations of the peripheral nervous system.	SHANK3 SHANK2	1.47e-05	2	134	2	20800661
Pubmed	SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis.	SHANK3 SHANK2	1.47e-05	2	134	2	36845137
Pubmed	Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma.	ATM WDR17	1.47e-05	2	134	2	26536348
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	NUP98 VTA1 NCDN MSTO1 AIFM2 DHCR24 POFUT1	1.93e-05	212	134	7	33462405
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANK3 BTBD9 SHANK3 NCDN MAP3K5 SHANK2 RACK1 ANAPC1 RPTOR PI4KA EIF4G1 TRAPPC3 ATP2B4 CDH11	2.24e-05	963	134	14	28671696
Pubmed	HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.	TTC28 RACK1 EIF4G1 UTRN EXOC4	2.26e-05	87	134	5	33711283
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	CLN8 ABL2 MYO18A RAB11FIP1 SHANK2 LPCAT3 SEC24B RAI14 HERC1 UTRN ATP2B4 TARBP1	2.36e-05	719	134	12	35337019
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	SEC16B DDX19A ANK3 VTA1 PHKA1 PI4KA RAI14 EXOC4	2.50e-05	304	134	8	32235678
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	EPRS1 NUP98 BCAR1 RAB11FIP1 PPP1R13L RPTOR SHCBP1 EIF4G1 ANKRD52 EXOC4	2.70e-05	503	134	10	16964243
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	ARFGEF1 ANKRD50 SNX19 ANKRD46 RPTOR PI4KA LPCAT3 SEC24B LRCH4 RAI14	2.74e-05	504	134	10	34432599
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	3.03e-05	46	134	4	17287250
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF1 PRAMEF2 PRAMEF13	3.66e-05	17	134	3	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF1 PRAMEF2 PRAMEF13	3.66e-05	17	134	3	37781892
Pubmed	ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.	ASB15 ASB12 ASB9	3.66e-05	17	134	3	16325183
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ABL2 ANK3 ANKRD50 RAB11FIP1 PI4KA RAI14 UTRN ATP2B4 EXOC4	3.94e-05	421	134	9	36976175
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	4.23e-05	50	134	4	31806660
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF1 PRAMEF2 PRAMEF13	4.37e-05	18	134	3	39181896
Pubmed	Regulation of cellular response to oncogenic and oxidative stress by Seladin-1.	MDM2 DHCR24	4.41e-05	3	134	2	15577914
Pubmed	Curcumin enhances the antitumor effect of ABT-737 via activation of the ROS-ASK1-JNK pathway in hepatocellular carcinoma cells.	MAP3K5 ROS1	4.41e-05	3	134	2	26707143
Pubmed	Hepatitis C virus impairs p53 via persistent overexpression of 3beta-hydroxysterol Delta24-reductase.	MDM2 DHCR24	4.41e-05	3	134	2	19861417
Pubmed	Translational neurobiology in Shank mutant mice--model systems for neuropsychiatric disorders.	SHANK3 SHANK2	4.41e-05	3	134	2	25917711
Pubmed	ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage.	MDM2 ATM	4.41e-05	3	134	2	19015526
Pubmed	Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.	SHANK3 SHANK2	4.41e-05	3	134	2	29970989
Pubmed	Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.	MDM2 ATM	4.41e-05	3	134	2	26965143
Pubmed	Aberrant expression of NLRP3, NLRC4 and NLRP6 inflammasomes in patients with primary immune thrombocytopenia.	NLRC4 NLRP6	4.41e-05	3	134	2	30802690
Pubmed	S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.	SHANK3 SHANK2	4.41e-05	3	134	2	34741005
Pubmed	Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.	ADGRA2 ADGRA3	4.41e-05	3	134	2	15021905
Pubmed	The Shank family of scaffold proteins.	SHANK3 SHANK2	4.41e-05	3	134	2	10806096
Pubmed	Allosteric changes in HDM2 by the ATM phosphomimetic S395D mutation: implications on HDM2 function.	MDM2 ATM	4.41e-05	3	134	2	31652301
Pubmed	Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.	MDM2 ATM	4.41e-05	3	134	2	23405218
Pubmed	Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.	MDM2 ATM	4.41e-05	3	134	2	15788536
Pubmed	DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction.	MDM2 ATM	4.41e-05	3	134	2	22976441
Pubmed	Statins use a novel Nijmegen breakage syndrome-1-dependent pathway to accelerate DNA repair in vascular smooth muscle cells.	MDM2 ATM	4.41e-05	3	134	2	18723444
Pubmed	Ribosomal RACK1:Protein Kinase C βII Phosphorylates Eukaryotic Initiation Factor 4G1 at S1093 To Modulate Cap-Dependent and -Independent Translation Initiation.	RACK1 EIF4G1	4.41e-05	3	134	2	30012863
Pubmed	Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding.	RACK1 EIF4G1	4.41e-05	3	134	2	30012864
Pubmed	Modeling autism by SHANK gene mutations in mice.	SHANK3 SHANK2	4.41e-05	3	134	2	23583105
Pubmed	Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients.	SHANK3 SHANK2	4.41e-05	3	134	2	32564287
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	EPRS1 SEC16B NUP98 MYO18A ADCY6 PAXBP1 ANAPC1 RPTOR SHCBP1 EIF4G1 PACS2 ATM	4.81e-05	774	134	12	15302935
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ANK3 NUP98 BCAR1 RAB11FIP1 PPP1R13L SNX19 PHKA1 PI4KA SEC24B RAI14 HERC1 ANKRD52 UTRN ATP2B4	5.64e-05	1049	134	14	27880917
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ANK3 BTBD9 SHANK3 NCDN MAP3K5 SHANK2 RACK1	5.65e-05	251	134	7	27507650
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ANK3 PFKL BTBD9 BCAR1 NCDN ANKRD44 UBE2E2 SHANK2 RPTOR LPCAT3 SLC16A14 USP40 DIP2C RAI14 OLFM2 UTRN EXOC4	6.16e-05	1489	134	17	28611215
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	DDX19A NUP98 PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14 SF3B6 SUPT7L	6.34e-05	347	134	8	16033648
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PFKL RAB11FIP1 PAXBP1 SHANK2 RACK1 ANAPC1 PI4KA DHCR24 SF3B6 SUPT7L SEC24B EIF4G1 LRCH4 EIF3K RAI14 HCFC2 UTRN	6.58e-05	1497	134	17	31527615
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EPRS1 DDX19A VTA1 PFKL RACK1 UPF2 RPTOR PI4KA SF3B6 SHCBP1 SEC24B EIF4G1 RAI14 ANKRD52 UTRN EXOC4	6.85e-05	1353	134	16	29467282
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	EPRS1 ARFGEF1 PFKL NCDN TRAPPC3 EXOC4	8.04e-05	183	134	6	23956138
Pubmed	SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.	SHANK3 SHANK2	8.80e-05	4	134	2	23897824
Pubmed	LRRK2 interacts with ATM and regulates Mdm2-p53 cell proliferation axis in response to genotoxic stress.	MDM2 ATM	8.80e-05	4	134	2	28973420
Pubmed	ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.	MDM2 ATM	8.80e-05	4	134	2	16082221
Pubmed	GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.	PPP1R13L ATM	8.80e-05	4	134	2	30128886
Pubmed	Genetic polymorphisms in ATM, ERCC1, APE1 and iASPP genes and lung cancer risk in a population of southeast China.	PPP1R13L ATM	8.80e-05	4	134	2	20354815
Pubmed	Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.	ADCY6 USH2A	8.80e-05	4	134	2	37127773
Pubmed	p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2).	PAK6 MDM2	8.80e-05	4	134	2	23132866
Pubmed	Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.	SHANK3 SHANK2	8.80e-05	4	134	2	23468870
Pubmed	SMG7 is a critical regulator of p53 stability and function in DNA damage stress response.	MDM2 ATM	8.80e-05	4	134	2	27462439
Pubmed	ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.	MDM2 ATM	8.80e-05	4	134	2	19816404
Pubmed	The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.	SHANK3 SHANK2	8.80e-05	4	134	2	12626503
Pubmed	HDMX folds the nascent p53 mRNA following activation by the ATM kinase.	MDM2 ATM	8.80e-05	4	134	2	24813712
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA7A ADGRA2 KCNH3 MAP3K5 SHANK2 RPTOR PI4KA EIF4G1 USP40 DIP2C ULK4 POFUT1 LTK HERC1	9.78e-05	1105	134	14	35748872
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	MYO18A UBE2E2 RACK1 EIF4G1 RAI14 UTRN	1.02e-04	191	134	6	33762435
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ABL2 ANK3 BTBD9 SHANK3 NCDN SHANK2 PI4KA	1.14e-04	281	134	7	28706196
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABL2 TTC28 BCAR1 PAK6 RAB11FIP1 RPTOR PI4KA SEC24B EIF4G1 RAI14 UTRN EXOC4	1.31e-04	861	134	12	36931259
Pubmed	USP10 regulates p53 localization and stability by deubiquitinating p53.	MDM2 ATM	1.46e-04	5	134	2	20096447
Pubmed	Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.	NLRC4 NLRP6	1.46e-04	5	134	2	23071280
Pubmed	Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.	SHANK3 SHANK2	1.46e-04	5	134	2	16606358
Pubmed	ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.	MDM2 ATM	1.46e-04	5	134	2	19965871
Pubmed	A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.	MDM2 ATM	1.46e-04	5	134	2	22588298
Cytoband	1p36.21	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	3.62e-05	63	134	4	1p36.21
Cytoband	6q22	ROS1 DSE	2.34e-04	8	134	2	6q22
GeneFamily	Ankyrin repeat domain containing	ANK3 ANKRD50 ASB15 PPP1R13L ASB12 SHANK3 ANKRD46 ANKRD44 SHANK2 ASB9 ABTB1 RAI14 ANKRD52 ANKRD7	3.68e-11	242	96	14	403
GeneFamily	PRAME family	PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14	7.31e-06	24	96	4	686
GeneFamily	Immunoglobulin like domain containing\|Adhesion G protein-coupled receptors, subfamily A	ADGRA2 ADGRA3	8.34e-05	3	96	2	911
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD44 ANKRD52	4.13e-04	6	96	2	699
GeneFamily	WD repeat domain containing	CDC20B WDFY4 RACK1 RPTOR HERC1 WDR17 DCAF4L1	4.93e-04	262	96	7	362
GeneFamily	TLC domain containing	CLN8 TRAM2	1.22e-03	10	96	2	1374
GeneFamily	Maestro heat like repeat containing	MROH9 MROH2B	1.49e-03	11	96	2	636
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 TTC28 BTBD9 SHANK2 DIP2C HERC1 UTRN EXOC4	1.65e-07	199	134	8	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RASGRF2 SHANK3 HMCN2 DHH SLC16A14 UTRN	1.73e-06	189	134	7	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 TTC28 BTBD9 UBE2E2 SHANK2 DIP2C EXOC4	1.92e-06	192	134	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 TTC28 BTBD9 ANKRD44 SHANK2 DIP2C EXOC4	2.20e-06	196	134	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDC20B SUCNR1 WDFY4 KCNH3 HMCN2 TARBP1	5.37e-06	146	134	6	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RASGRF2 PPP1R13L GPR146 POFUT1 LTK ANKRD52	1.37e-05	172	134	6	d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA7A RASGRF2 ADGRA2 SHANK3 DHH SLC16A14	1.46e-05	174	134	6	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|tumor_Lung / Location, Cell class and cell subclass	ABL2 SEMA7A SUCNR1 FCGBP UBE2E2 OLFM2	1.89e-05	182	134	6	243779ba1009097f8fafa1a691e296ec3aeefc04
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF2 ADCY6 DHH OLFM2 UTRN ATP2B4	2.13e-05	186	134	6	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	EPRS1 EXD1 ASTE1 PAK6 PAXBP1 UTRN	2.40e-05	190	134	6	373629dde5eda722424c5e6087763f0c5db67cf4
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ANK3 ARFGEF1 BTBD9 ANKRD44 ATM HERC1	2.55e-05	192	134	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 OPRD1 ANKRD44 ATM HERC1 UTRN	2.62e-05	193	134	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTC28 RASGRF2 SHANK3 HMCN2 SLC16A14 UTRN	2.78e-05	195	134	6	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	ANK3 SHANK2 DHCR24 RAI14 ROS1 ATP2B4	2.78e-05	195	134	6	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	ANK3 SHANK2 DHCR24 RAI14 ROS1 ATP2B4	2.78e-05	195	134	6	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	Sepsis-Int-URO-Lymphocyte-B-Plasmablast\|Int-URO / Disease, condition lineage and cell class	KCTD1 PPP1R13L ANKRD46 AIFM2 SHCBP1 LTK	2.86e-05	196	134	6	e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	RNF175 MSTO1 HERC1 UTRN ATP2B4 DCAF4L1	3.03e-05	198	134	6	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 TTC28 BTBD9 SHANK2 DIP2C EXOC4	3.03e-05	198	134	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 ARFGEF1 ANKRD44 ATM HERC1 UTRN	3.11e-05	199	134	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANK3 BTBD9 MSTO1 TRAPPC3 WDR17 UTRN	3.11e-05	199	134	6	121de4e02585de3a3010398387c523bacf8ce546
Disease	nighttime rest measurement	SEC16B MYO18A DNAJC10	1.37e-04	24	124	3	EFO_0007827
Disease	Alcoholic Intoxication, Chronic	RASGRF2 AKR1A1 OPRD1 RACK1 ANAPC1 CDH11 ANKRD7	1.44e-04	268	124	7	C0001973
Disease	isovalerylcarnitine measurement	IVD SLC22A4	3.63e-04	7	124	2	EFO_0020019
Disease	depressive symptom measurement, response to antidepressant	WDFY4 ANKRD44 DIP2C ATP2B4	5.27e-04	88	124	4	EFO_0007006, GO_0036276
Disease	obesity	SEC16B TTC28 NUP98 HNF4G RPTOR EXOC4	5.58e-04	241	124	6	EFO_0001073
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	SEC16B HNF4G SNX19 ANKRD44 RPTOR TRAM2 ATP2B4	8.99e-04	364	124	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	testosterone measurement	ANK3 TTC28 MAU2 ADCY6 NLRC4 IVD UBE2E2 ANAPC1 UGT2B10 C2 TRAM2 USH2A UTRN ATP2B4	9.55e-04	1275	124	14	EFO_0004908
Disease	body fat percentage	SEC16B HNF4G SNX19 ANKRD44 RPTOR ULK4 TRAM2 ATP2B4	1.09e-03	488	124	8	EFO_0007800
Disease	lower face morphology measurement	MROH9 ITGA11 ANAPC1 NAV3	1.18e-03	109	124	4	EFO_0010948
Disease	DNA methylation	TEX261 SEC16B ANKRD50 ANKRD44 MROH2B USH2A ATP2B4 CDH11 EXOC4	1.85e-03	656	124	9	GO_0006306
Disease	eye morphology measurement	CLN8 PHKA1 NAV3 ULK4 PAPPA	2.32e-03	218	124	5	EFO_0007858
Disease	Colorectal Carcinoma	RASGRF2 ARFGEF1 PAK6 NCDN VSTM4 EIF4G1 DIP2C OLFM2 EXOC4	2.91e-03	702	124	9	C0009402
Disease	bipolar I disorder	ANK3 SHANK2 DHH ATP2B4	3.01e-03	141	124	4	EFO_0009963
Disease	bipolar disorder	ANK3 MAU2 SNX19 SHANK2 DHH RPTOR ATP2B4 TARBP1	3.09e-03	577	124	8	MONDO_0004985
Disease	psychotic symptoms	ANK3 WDFY4 DIP2C	3.78e-03	74	124	3	EFO_0005940
Disease	melanoma	MDM2 MAP3K5 UGT2B10 ROS1 ATM	4.03e-03	248	124	5	C0025202
Disease	interleukin 18 measurement	NLRC4 ANKRD44 AIFM2	4.07e-03	76	124	3	EFO_0004581
Disease	carnitine measurement	ANK3 IVD SLC22A4	4.07e-03	76	124	3	EFO_0010469
Disease	sex interaction measurement, body mass index, age at assessment	SEC16B HNF4G	4.18e-03	23	124	2	EFO_0004340, EFO_0008007, EFO_0008343

Protein segments in the cluster

Peptide	Gene	Start	Entry
HVECVNSLIAYGGNI	ASB9	146	Q96DX5
NSQLVDTGHQLLDYC	ABL2	1106	P42684
ALCYATQLVNILSHI	ATG14	306	Q6ZNE5
QVTHYSNLLCDLLRG	BCAR1	811	P56945
LIICGITAAVNIHNY	ADGRA2	896	Q96PE1
ACHLQQLNYSLGLDA	ADCY6	786	O43306
NASICQAVGIILHYS	ADGRA3	821	Q8IWK6
DCLQKLIAYGHLTGN	ARFGEF1	101	Q9Y6D6
VRLLLSHGANVNCYF	ASB15	396	Q8WXK1
CLLHSALLGAYTFQQ	C19orf84	66	I3L1E1
LASQEGHYDCVQILL	ANKRD50	886	Q9ULJ7
TALHIACYLGQDAVA	ANKRD52	241	Q8NB46
LLATDYQGNTALHLC	ANKRD46	71	Q86W74
LYSGSLVHGLCQQLL	ASTE1	571	Q2TB18
LTQINVHYGGVQNLC	ATP2B4	41	P23634
NQIVCGYAHTLALTD	RCBTB1	236	Q8NDN9
TALHYAAAQGCLQAV	RAI14	121	Q9P0K7
ICGVLYVTNSHLAGA	OLFM2	376	O95897
HLYTLDGGDIINALC	RACK1	226	P63244
TYCVLQCLQLAGLHD	KCNH3	666	Q9ULD8
QCLQLAGLHDSLALY	KCNH3	671	Q9ULD8
AACQLVSLEGLSLYH	LRCH4	86	O75427
VLHLGYNGICNLIQL	LRRC9	1206	Q6ZRR7
LNSYQFHIVNGAVVC	PLA2G2C	81	Q5R387
TLSQAHVYIIAGACL	ANAPC1	1456	Q9H1A4
NYTHLSAQCEGVLQA	NUP98	1536	P52948
GCTAQHFLYLTLVGA	OR2T1	146	O43869
VCEAVLQALAYLHAQ	PAK6	506	Q9NQU5
CIVTAGQLANAHIDY	HCFC2	741	Q9Y5Z7
HLIAGGTVSALCQAY	NCDN	171	Q9UBB6
AVYQHGCLLGLSIAK	NLRC4	511	Q9NPP4
VLAQDAGHYLCLASN	HMCN2	3746	Q8NDA2
LDGYARLVQQTILCH	PHKA1	11	P46020
AASYGHLSCLQVLLA	ASB12	71	Q8WXK4
GHLNLYLLLDCSQSV	C2	251	P06681
CLSHQYGILLNNVFD	EXD1	166	Q8NHP7
YQIGQVACGLNHTLA	HERC1	4186	Q15751
AYHCFSAGLSQQVLL	DCAF4L1	196	Q3SXM0
LQLAQDIAQGCHYLE	LTK	621	P29376
SALCQGLYFHINQTL	FAM104A	156	Q969W3
VVGNCLQIASDSHQY	PCMTD1	146	Q96MG8
CGDIHVNNIYGLLVI	OR51I1	191	Q9H343
CELNANAYSIHTVGL	MUC19	1361	Q7Z5P9
HACTTGEEILAQYLQ	MSTO1	441	Q9BUK6
NGYCHLNSVQVLERL	KCTD1	196	Q719H9
TSCQHLVQYLATIAG	MYO18A	506	Q92614
AAYNLVQHGITNLCV	PFKL	101	P17858
IASYCIGDLIRSHNL	NAV3	1981	Q8IVL0
GYRHCSLAVINALAN	PI4KA	701	P42356
AAQLTYHGLCELTAA	MINDY1	291	Q8N5J2
FGNQLYHSLLCIVLQ	LPCAT3	86	Q6P1A2
AQSLHGQRCLYAVLL	DSE	926	Q9UL01
TALHIACYNGQDAVV	ANKRD44	241	Q8N8A2
LQYFGCSIHGQLDLN	ITGA11	601	Q9UKX5
LVHLADTIYRNSIGC	PAXBP1	856	Q9Y5B6
HLCLEGRILVQYASN	PAPPA	711	Q13219
RITQYIAGANCAHQL	PACS2	636	Q86VP3
GLSYGAHSNLCINQL	IVD	126	P26440
HLLYIARCQNDIGTN	MROH9	196	Q5TGP6
LLGNNYVIHRNSCEV	HNF4G	196	Q14541
VVAALHLCIALGYAN	OPRD1	296	P41143
HLISCILINGAQYFR	EXOC4	846	Q96A65
QALQNLGLCHILSVY	ATM	2066	Q13315
LLQHYLHAGVSECLN	C3orf84	181	H3BNL1
ILAENCEAALALHLY	GLT1D1	51	Q96MS3
HGTLLVNDVLASCYA	DHH	331	O43323
GNLSILCSNIHAYVS	FCGBP	1496	Q9Y6R7
GGNLSILCSNIHAYV	FCGBP	2696	Q9Y6R7
GLFQHICTAYELVLA	DHCR24	181	Q15392
LLSCNAEAYILNAGL	CDH11	601	P55287
HILYTLLNCRGAIAN	DIP2C	986	Q9Y2E4
LCQFTTLGGVYHLDI	DNAI7	376	Q6TDU7
NTVLHYAVCGQSLSL	ANKRD7	126	Q92527
IAAHYGNINVATLLL	ANK3	241	Q12955
QILYLGDLLETCHFQ	EIF3K	101	Q9UBQ5
LHQLLCAGHLSTAQY	EIF4G1	1301	Q04637
HNGIENIDLSLTCNY	CDC20B	261	Q86Y33
TGLINVGSIDCQQYH	DNAJC10	606	Q8IXB1
GLCYNALLVLANLHS	GPR146	41	Q96CH1
QALCNLYGAITIAQA	DDX19A	321	Q9NUU7
YTCHQLGSGAIVVQL	BTBD9	461	Q96Q07
VSHNAVEAGYLTILC	SEC24B	686	O95487
LHGDAYLNCFLSALI	SLC22A4	366	Q9H015
NHAAQLHTLLGLYCV	MAU2	376	Q9Y6X3
ITALHNAICGANYSI	PPP1R13L	661	Q8WUF5
YLCAVLQHQGCGLQT	NLRP6	831	P59044
LEGCQIHYSQLSAIL	PRAMEF13	356	Q5VWM6
FLGCRQYLSLHVSLN	OR9A2	86	Q8NGT5
YNSIHCVANLLAGLV	UPF2	821	Q9HAU5
LYILGQADHFIGNCV	POFUT1	341	Q9H488
SGINYAVLLLAAGHQ	MAP3K5	431	Q99683
LLNSYQHLCLEQGFG	USH2A	1846	O75445
HALIQQYCQTLGGES	UTRN	3226	P46939
VLSRSNVCINGNHVY	RAB11FIP1	311	Q6WKZ4
ELNHCLSLRTYLVGN	EPRS1	101	P07814
SLLVAVQLCYANVNG	TAAR6	6	Q96RI8
YLAGLHANIAVANIV	AIFM2	296	Q9BRQ8
EHLANAYGIIICANG	SLC16A14	436	Q7RTX9
LEGCQIHYSQLSAIL	PRAMEF14	356	Q5SWL7
CLHNYNGVLEITSAL	RASGRF2	1086	O14827
QQHIVYCSNDLLGDL	MDM2	71	Q00987
LEGCQIHYSQLSAIL	PRAMEF1	356	O95521
YTQDACINILNGHTA	WDR17	596	Q8IZU2
SGLIVDYHNLLSQCE	SHCBP1	241	Q8NEM2
QLLYQAVATILAHAG	SUPT7L	156	O94864
LEGCQIHYSQLSAIL	PRAMEF2	356	O60811
QGITSILGYCAENHL	MROH2B	651	Q7Z745
YHTGQEACLQGNLIA	RPTOR	546	Q8N122
GNTALHICALYNQDS	SHANK2	331	Q9UPX8
CGHEELVLYLLANGA	ABTB1	46	Q969K4
LIAHCQARGLEVTAY	AKR1A1	196	P14550
FLGCLVNLQAGHYLA	CLN8	146	Q9UBY8
QATGHVLLGTSCYLQ	CIDEC	196	Q96AQ7
LYHCIVLLENAALTG	XKR7	386	Q5GH72
RIYHCNINSQGVICL	UBE2E2	126	Q96LR5
GAHGYCTQELVNLLL	MINDY4	596	Q4G0A6
CALNHSLQDALNYGL	SHANK3	41	Q9BYB0
ASGNTALHICALYNQ	SHANK3	281	Q9BYB0
TQEIVGCAHLENYAL	VTA1	81	Q9NP79
EGLIENTYQLSCNHV	RNF175	241	Q8N4F7
HLSGFNVCNRYLVVL	SF3B6	76	Q9Y3B4
NHSSLIYSNLLCGVL	TRAPPC3	121	O43617
QLQYICLYLVHIAGA	TRAM2	191	Q15035
QALYGHTQAVTCLAA	WDFY4	2976	Q6ZS81
CILFIENLTAQQYGH	SEMA7A	596	O75326
EGAVYHLANCLLLLG	POPDC2	26	Q9HBU9
DSQCIHLYTAVLRGQ	ROS1	851	P08922
NFILSCGLVVVNHYL	TEX261	96	Q6UWH6
QSVLTLCGCHLQSYI	SNX19	156	Q92543
GDVLCISNRYVLHAN	SUCNR1	91	Q9BXA5
GLVSQALHYCEAIGA	SEC16B	641	Q96JE7
ALHYCEAIGAAVLSQ	SEC16B	646	Q96JE7
LHSQLGNYEQAISCL	TTC28	966	Q96AY4
QYHSLDVIGFLLACV	UGT2B10	486	P36537
ASGNSLYQRNLCLHL	TTC37	341	Q6PGP7
YLEGENATLLCHVSQ	VSTM4	36	Q8IW00
THQILLRGAAQCYLL	TARBP1	521	Q13395
GSSILVQCHYRLQDV	TREML1	31	Q86YW5
QGGTCYLNSLLQTLH	USP40	46	Q9NVE5
EAQALITQGLYSHCR	TTC34	256	A8MYJ7
ITQGLYSHCRALLSQ	TTC34	261	A8MYJ7
LNLLCYLCVVAGHQE	ULK4	486	Q96C45
LLYEQGLVSHICNLL	ULK4	1071	Q96C45