Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cadherin binding	RPL24 FLNB PDLIM5 AHNAK MPP7	1.89e-04	339	32	5	GO:0045296
GeneOntologyMolecularFunction	cytoskeletal protein binding	NEFM TMOD2 TPR DIP2B FLNB FLNC SYNM PDLIM5	2.64e-04	1099	32	8	GO:0008092
GeneOntologyMolecularFunction	cell adhesion molecule binding	RPL24 TMIGD1 FLNB PDLIM5 AHNAK MPP7	3.31e-04	599	32	6	GO:0050839
GeneOntologyMolecularFunction	structural molecule activity	NEFM ERVK-5 TPR RPL24 SYNM AHNAK	2.60e-03	891	32	6	GO:0005198
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	TMIGD1 PDLIM5	4.29e-03	61	32	2	GO:0098632
GeneOntologyBiologicalProcess	positive regulation of metanephric DCT cell differentiation	PAX2 PAX8	2.33e-06	2	32	2	GO:2000594
GeneOntologyBiologicalProcess	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	PAX2 PAX8	2.33e-06	2	32	2	GO:0072305
GeneOntologyBiologicalProcess	regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	PAX2 PAX8	2.33e-06	2	32	2	GO:0072304
GeneOntologyBiologicalProcess	kidney field specification	PAX2 PAX8	2.33e-06	2	32	2	GO:0072004
GeneOntologyBiologicalProcess	regulation of apoptotic process involved in metanephric collecting duct development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900214
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in metanephric collecting duct development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900215
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in metanephric nephron tubule development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900218
GeneOntologyBiologicalProcess	regulation of apoptotic process involved in metanephric nephron tubule development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900217
GeneOntologyBiologicalProcess	pronephric field specification	PAX2 PAX8	2.33e-06	2	32	2	GO:0039003
GeneOntologyBiologicalProcess	mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	PAX2 PAX8	2.33e-06	2	32	2	GO:1901147
GeneOntologyBiologicalProcess	pattern specification involved in pronephros development	PAX2 PAX8	2.33e-06	2	32	2	GO:0039017
GeneOntologyBiologicalProcess	apoptotic process involved in metanephric nephron tubule development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900205
GeneOntologyBiologicalProcess	apoptotic process involved in metanephric collecting duct development	PAX2 PAX8	2.33e-06	2	32	2	GO:1900204
GeneOntologyBiologicalProcess	regulation of metanephric DCT cell differentiation	PAX2 PAX8	2.33e-06	2	32	2	GO:2000592
GeneOntologyBiologicalProcess	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis	PAX2 PAX8	6.99e-06	3	32	2	GO:0072309
GeneOntologyBiologicalProcess	metanephric DCT cell differentiation	PAX2 PAX8	6.99e-06	3	32	2	GO:0072240
GeneOntologyBiologicalProcess	kidney rudiment formation	PAX2 PAX8	6.99e-06	3	32	2	GO:0072003
GeneOntologyBiologicalProcess	DCT cell differentiation	PAX2 PAX8	6.99e-06	3	32	2	GO:0072069
GeneOntologyBiologicalProcess	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	PAX2 PAX8	1.40e-05	4	32	2	GO:0072108
GeneOntologyBiologicalProcess	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	PAX2 PAX8	1.40e-05	4	32	2	GO:1900212
GeneOntologyBiologicalProcess	regulation of mesenchymal cell apoptotic process involved in metanephros development	PAX2 PAX8	1.40e-05	4	32	2	GO:1900211
GeneOntologyBiologicalProcess	mesenchymal cell apoptotic process involved in nephron morphogenesis	PAX2 PAX8	1.40e-05	4	32	2	GO:1901145
GeneOntologyBiologicalProcess	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	PAX2 PAX8	1.40e-05	4	32	2	GO:0072040
GeneOntologyBiologicalProcess	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	PAX2 PAX8	1.40e-05	4	32	2	GO:0072039
GeneOntologyBiologicalProcess	metanephric nephron tubule formation	PAX2 PAX8	1.40e-05	4	32	2	GO:0072289
GeneOntologyBiologicalProcess	mesenchymal cell apoptotic process involved in metanephros development	PAX2 PAX8	1.40e-05	4	32	2	GO:1900200
GeneOntologyBiologicalProcess	metanephric distal convoluted tubule development	PAX2 PAX8	2.33e-05	5	32	2	GO:0072221
GeneOntologyBiologicalProcess	metanephric distal tubule development	PAX2 PAX8	2.33e-05	5	32	2	GO:0072235
GeneOntologyBiologicalProcess	distal convoluted tubule development	PAX2 PAX8	2.33e-05	5	32	2	GO:0072025
GeneOntologyBiologicalProcess	negative regulation of somatic stem cell population maintenance	PAX2 PAX8	2.33e-05	5	32	2	GO:1904673
GeneOntologyBiologicalProcess	metanephric tubule formation	PAX2 PAX8	3.48e-05	6	32	2	GO:0072174
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in morphogenesis	PAX2 PAX8	4.87e-05	7	32	2	GO:1902338
GeneOntologyBiologicalProcess	regulation of metanephric nephron tubule epithelial cell differentiation	PAX2 PAX8	4.87e-05	7	32	2	GO:0072307
GeneOntologyBiologicalProcess	positive regulation of epithelial cell differentiation involved in kidney development	PAX2 PAX8	4.87e-05	7	32	2	GO:2000698
GeneOntologyBiologicalProcess	metanephric collecting duct development	PAX2 PAX8	4.87e-05	7	32	2	GO:0072205
GeneOntologyBiologicalProcess	metanephric nephron tubule epithelial cell differentiation	PAX2 PAX8	4.87e-05	7	32	2	GO:0072257
GeneOntologyBiologicalProcess	metanephric nephron tubule morphogenesis	PAX2 PAX8	4.87e-05	7	32	2	GO:0072282
GeneOntologyBiologicalProcess	mesenchymal stem cell maintenance involved in nephron morphogenesis	PAX2 PAX8	4.87e-05	7	32	2	GO:0072038
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in development	PAX2 PAX8	6.49e-05	8	32	2	GO:1904746
GeneOntologyBiologicalProcess	pattern specification involved in kidney development	PAX2 PAX8	6.49e-05	8	32	2	GO:0061004
GeneOntologyBiologicalProcess	renal system pattern specification	PAX2 PAX8	6.49e-05	8	32	2	GO:0072048
GeneOntologyBiologicalProcess	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	PAX2 PAX8	8.34e-05	9	32	2	GO:0003339
GeneOntologyBiologicalProcess	metanephric tubule morphogenesis	PAX2 PAX8	1.04e-04	10	32	2	GO:0072173
GeneOntologyBiologicalProcess	distal tubule development	PAX2 PAX8	1.04e-04	10	32	2	GO:0072017
GeneOntologyBiologicalProcess	pronephros development	PAX2 PAX8	1.04e-04	10	32	2	GO:0048793
GeneOntologyBiologicalProcess	mesenchymal to epithelial transition involved in metanephros morphogenesis	PAX2 PAX8	1.52e-04	12	32	2	GO:0003337
GeneOntologyBiologicalProcess	regulation of nephron tubule epithelial cell differentiation	PAX2 PAX8	1.80e-04	13	32	2	GO:0072182
GeneOntologyBiologicalProcess	negative regulation of mesenchymal cell apoptotic process	PAX2 PAX8	1.80e-04	13	32	2	GO:2001054
GeneOntologyBiologicalProcess	regulation of somatic stem cell population maintenance	PAX2 PAX8	1.80e-04	13	32	2	GO:1904672
GeneOntologyBiologicalProcess	collecting duct development	PAX2 PAX8	1.80e-04	13	32	2	GO:0072044
GeneOntologyBiologicalProcess	regulation of apoptotic process involved in morphogenesis	PAX2 PAX8	2.42e-04	15	32	2	GO:1902337
GeneOntologyBiologicalProcess	nephron tubule epithelial cell differentiation	PAX2 PAX8	2.42e-04	15	32	2	GO:0072160
GeneOntologyBiologicalProcess	metanephric renal vesicle morphogenesis	PAX2 PAX8	2.42e-04	15	32	2	GO:0072283
GeneOntologyBiologicalProcess	regulation of apoptotic process involved in development	PAX2 PAX8	3.13e-04	17	32	2	GO:1904748
GeneOntologyBiologicalProcess	regulation of mesenchymal cell apoptotic process	PAX2 PAX8	3.13e-04	17	32	2	GO:2001053
GeneOntologyBiologicalProcess	renal vesicle morphogenesis	PAX2 PAX8	3.51e-04	18	32	2	GO:0072077
GeneOntologyBiologicalProcess	positive regulation of protein acetylation	DIP2B KAT5	3.51e-04	18	32	2	GO:1901985
GeneOntologyBiologicalProcess	mesenchymal cell apoptotic process	PAX2 PAX8	3.92e-04	19	32	2	GO:0097152
GeneOntologyBiologicalProcess	regulation of epithelial cell differentiation involved in kidney development	PAX2 PAX8	3.92e-04	19	32	2	GO:2000696
GeneOntologyBiologicalProcess	renal vesicle development	PAX2 PAX8	3.92e-04	19	32	2	GO:0072087
GeneOntologyBiologicalProcess	mesenchymal to epithelial transition	PAX2 PAX8	4.35e-04	20	32	2	GO:0060231
GeneOntologyBiologicalProcess	metanephric nephron tubule development	PAX2 PAX8	4.81e-04	21	32	2	GO:0072234
GeneOntologyBiologicalProcess	optic nerve development	RPL24 PAX2	5.28e-04	22	32	2	GO:0021554
GeneOntologyBiologicalProcess	positive regulation of branching involved in ureteric bud morphogenesis	PAX2 PAX8	5.28e-04	22	32	2	GO:0090190
GeneOntologyBiologicalProcess	cell differentiation involved in metanephros development	PAX2 PAX8	5.28e-04	22	32	2	GO:0072202
GeneOntologyBiologicalProcess	metanephric nephron epithelium development	PAX2 PAX8	5.78e-04	23	32	2	GO:0072243
GeneOntologyBiologicalProcess	nephron tubule formation	PAX2 PAX8	5.78e-04	23	32	2	GO:0072079
GeneOntologyBiologicalProcess	metanephric nephron morphogenesis	PAX2 PAX8	5.78e-04	23	32	2	GO:0072273
GeneOntologyBiologicalProcess	regulation of branching involved in ureteric bud morphogenesis	PAX2 PAX8	6.30e-04	24	32	2	GO:0090189
GeneOntologyBiologicalProcess	metanephric tubule development	PAX2 PAX8	7.40e-04	26	32	2	GO:0072170
GeneOntologyBiologicalProcess	negative regulation of stem cell population maintenance	PAX2 PAX8	7.40e-04	26	32	2	GO:1902455
GeneOntologyBiologicalProcess	peptidyl-lysine acetylation	DIP2B KAT5	8.60e-04	28	32	2	GO:0018394
GeneOntologyBiologicalProcess	metanephric epithelium development	PAX2 PAX8	8.60e-04	28	32	2	GO:0072207
GeneOntologyBiologicalProcess	regulation of protein acetylation	DIP2B KAT5	8.60e-04	28	32	2	GO:1901983
GeneOntologyBiologicalProcess	metanephros morphogenesis	PAX2 PAX8	9.22e-04	29	32	2	GO:0003338
GeneOntologyBiologicalProcess	apoptotic process involved in morphogenesis	PAX2 PAX8	1.12e-03	32	32	2	GO:0060561
GeneOntologyBiologicalProcess	ventricular system development	PAX5 HYDIN	1.58e-03	38	32	2	GO:0021591
GeneOntologyBiologicalProcess	regulation of kidney development	PAX2 PAX8	1.58e-03	38	32	2	GO:0090183
GeneOntologyBiologicalProcess	metanephric nephron development	PAX2 PAX8	1.58e-03	38	32	2	GO:0072210
GeneOntologyBiologicalProcess	regulation of chromatin organization	TPR KAT5	1.75e-03	40	32	2	GO:1902275
GeneOntologyBiologicalProcess	muscle structure development	TMOD2 FLNB FLNC PAX5 KAT5 PDLIM5	1.82e-03	858	32	6	GO:0061061
GeneOntologyBiologicalProcess	specification of animal organ identity	PAX2 PAX8	1.84e-03	41	32	2	GO:0010092
GeneOntologyBiologicalProcess	positive regulation of morphogenesis of an epithelium	PAX2 PAX8	1.93e-03	42	32	2	GO:1905332
GeneOntologyBiologicalProcess	cell morphogenesis	NEFM RPL24 DIP2B FLNB PAX2 PDLIM5 CFDP1	2.01e-03	1194	32	7	GO:0000902
GeneOntologyBiologicalProcess	mitotic cell cycle checkpoint signaling	TPR RPL24 MDC1	2.03e-03	163	32	3	GO:0007093
GeneOntologyBiologicalProcess	apoptotic process involved in development	PAX2 PAX8	2.41e-03	47	32	2	GO:1902742
GeneOntologyBiologicalProcess	epithelial cell differentiation involved in kidney development	PAX2 PAX8	2.41e-03	47	32	2	GO:0035850
GeneOntologyBiologicalProcess	dopaminergic neuron differentiation	PAX2 PAX5	2.73e-03	50	32	2	GO:0071542
GeneOntologyBiologicalProcess	response to epidermal growth factor	TPR PAX2	3.17e-03	54	32	2	GO:0070849
GeneOntologyCellularComponent	myofibril	TMOD2 FLNB FLNC IGFN1 SYNM PDLIM5 AHNAK	1.53e-07	273	32	7	GO:0030016
GeneOntologyCellularComponent	contractile muscle fiber	TMOD2 FLNB FLNC IGFN1 SYNM PDLIM5 AHNAK	2.30e-07	290	32	7	GO:0043292
GeneOntologyCellularComponent	sarcomere	TMOD2 FLNB FLNC IGFN1 SYNM PDLIM5	1.88e-06	249	32	6	GO:0030017
GeneOntologyCellularComponent	Z disc	FLNB FLNC IGFN1 SYNM PDLIM5	3.17e-06	151	32	5	GO:0030018
GeneOntologyCellularComponent	costamere	FLNC SYNM AHNAK	4.92e-06	22	32	3	GO:0043034
GeneOntologyCellularComponent	I band	FLNB FLNC IGFN1 SYNM PDLIM5	5.03e-06	166	32	5	GO:0031674
GeneOntologyCellularComponent	anchoring junction	TMIGD1 FLNB FLNC SYNM PDLIM5 AHNAK MPP7 MDC1	8.48e-05	976	32	8	GO:0070161
GeneOntologyCellularComponent	Swr1 complex	KAT5 CFDP1	1.75e-04	13	32	2	GO:0000812
GeneOntologyCellularComponent	adherens junction	TMIGD1 SYNM PDLIM5 MPP7	2.96e-04	212	32	4	GO:0005912
GeneOntologyCellularComponent	supramolecular fiber	NEFM TMOD2 FLNB FLNC IGFN1 SYNM PDLIM5 AHNAK	3.12e-04	1179	32	8	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	NEFM TMOD2 FLNB FLNC IGFN1 SYNM PDLIM5 AHNAK	3.27e-04	1187	32	8	GO:0099081
GeneOntologyCellularComponent	INO80-type complex	KAT5 CFDP1	8.37e-04	28	32	2	GO:0097346
GeneOntologyCellularComponent	actin cytoskeleton	TMOD2 FLNB FLNC PDLIM5 AHNAK	1.70e-03	576	32	5	GO:0015629
GeneOntologyCellularComponent	cell-cell junction	TMIGD1 SYNM PDLIM5 AHNAK MPP7	1.90e-03	591	32	5	GO:0005911
GeneOntologyCellularComponent	kinetochore	TPR KAT5 CFDP1	2.63e-03	181	32	3	GO:0000776
GeneOntologyCellularComponent	sarcolemma	FLNC SYNM AHNAK	3.02e-03	190	32	3	GO:0042383
GeneOntologyCellularComponent	condensed chromosome, centromeric region	TPR KAT5 CFDP1	3.16e-03	193	32	3	GO:0000779
GeneOntologyCellularComponent	focal adhesion	FLNB FLNC AHNAK MDC1	4.06e-03	431	32	4	GO:0005925
GeneOntologyCellularComponent	cell-substrate junction	FLNB FLNC AHNAK MDC1	4.47e-03	443	32	4	GO:0030055
GeneOntologyCellularComponent	histone deacetylase complex	KAT5 CFDP1	7.49e-03	85	32	2	GO:0000118
GeneOntologyCellularComponent	inclusion body	NEFM TPR	8.36e-03	90	32	2	GO:0016234
GeneOntologyCellularComponent	chromosome, centromeric region	TPR KAT5 CFDP1	8.51e-03	276	32	3	GO:0000775
GeneOntologyCellularComponent	intercellular bridge	FLNC PCIF1	9.09e-03	94	32	2	GO:0045171
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	KAT5 CFDP1	9.46e-03	96	32	2	GO:0070603
GeneOntologyCellularComponent	site of double-strand break	KAT5 MDC1	1.04e-02	101	32	2	GO:0035861
GeneOntologyCellularComponent	condensed chromosome	TPR KAT5 CFDP1	1.14e-02	307	32	3	GO:0000793
GeneOntologyCellularComponent	contractile actin filament bundle	FLNB PDLIM5	1.16e-02	107	32	2	GO:0097517
GeneOntologyCellularComponent	stress fiber	FLNB PDLIM5	1.16e-02	107	32	2	GO:0001725
MousePheno	absent uterine horn	PAX2 PAX8	3.59e-06	2	27	2	MP:0009215
MousePheno	optic nerve coloboma	RPL24 PAX2	1.08e-05	3	27	2	MP:0010717
MousePheno	absent efferent ductules of testis	PAX2 PAX8	1.08e-05	3	27	2	MP:0004729
MousePheno	delayed optic fissure closure	RPL24 PAX2	3.58e-05	5	27	2	MP:0012536
MousePheno	abnormal optic fissure closure	RPL24 PAX2	1.28e-04	9	27	2	MP:0012535
MousePheno	absent epididymis	PAX2 PAX8	1.28e-04	9	27	2	MP:0004727
MousePheno	abnormal midbrain morphology	ADH7 PAX2 PAX5 HYDIN	1.89e-04	151	27	4	MP:0000897
MousePheno	abnormal efferent ductules of testis morphology	PAX2 PAX8	1.95e-04	11	27	2	MP:0004728
MousePheno	decreased B-1b cell number	NLRP1 PAX5	1.95e-04	11	27	2	MP:0008170
MousePheno	abnormal inner ear development	PAX2 PAX8	2.34e-04	12	27	2	MP:0011238
MousePheno	abnormal ear development	PCNP PAX2 PAX8	2.59e-04	65	27	3	MP:0003938
MousePheno	thin retina ganglion layer	RPL24 PAX2	3.71e-04	15	27	2	MP:0008507
MousePheno	abnormal oviduct morphology	PAX2 PAX8	4.24e-04	16	27	2	MP:0003574
MousePheno	abnormal sarcomere morphology	FLNC SYNM PDLIM5	4.27e-04	77	27	3	MP:0004090
MousePheno	abnormal uterine horn morphology	PAX2 PAX8	5.39e-04	18	27	2	MP:0009085
Domain	Pax2_C	PAX2 PAX5 PAX8	4.57e-09	3	32	3	IPR022130
Domain	Pax2_C	PAX2 PAX5 PAX8	4.57e-09	3	32	3	PF12403
Domain	PAX	PAX2 PAX5 PAX8	3.81e-07	9	32	3	SM00351
Domain	PAX	PAX2 PAX5 PAX8	3.81e-07	9	32	3	PF00292
Domain	Paired_dom	PAX2 PAX5 PAX8	3.81e-07	9	32	3	IPR001523
Domain	PAIRED_2	PAX2 PAX5 PAX8	3.81e-07	9	32	3	PS51057
Domain	PAIRED_1	PAX2 PAX5 PAX8	3.81e-07	9	32	3	PS00034
Domain	IG_FLMN	FLNB FLNC	1.27e-04	10	32	2	SM00557
Domain	Filamin	FLNB FLNC	1.55e-04	11	32	2	PF00630
Domain	Filamin/ABP280_rpt	FLNB FLNC	1.55e-04	11	32	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB FLNC	1.55e-04	11	32	2	IPR017868
Domain	FILAMIN_REPEAT	FLNB FLNC	1.55e-04	11	32	2	PS50194
Domain	Actinin_actin-bd_CS	FLNB FLNC	7.04e-04	23	32	2	IPR001589
Domain	ACTININ_2	FLNB FLNC	7.04e-04	23	32	2	PS00020
Domain	ACTININ_1	FLNB FLNC	7.04e-04	23	32	2	PS00019
Domain	WHTH_DNA-bd_dom	PAX2 PAX5 KAT5 PAX8	7.43e-04	242	32	4	IPR011991
Domain	PDZ	PDLIM5 AHNAK MPP7	1.78e-03	141	32	3	PF00595
Domain	PDZ	PDLIM5 AHNAK MPP7	2.04e-03	148	32	3	SM00228
Domain	-	PDLIM5 AHNAK MPP7	2.12e-03	150	32	3	2.30.42.10
Domain	PDZ	PDLIM5 AHNAK MPP7	2.16e-03	151	32	3	PS50106
Domain	PDZ	PDLIM5 AHNAK MPP7	2.20e-03	152	32	3	IPR001478
Domain	Intermediate_filament_CS	NEFM SYNM	5.20e-03	63	32	2	IPR018039
Domain	CH	FLNB FLNC	5.53e-03	65	32	2	SM00033
Domain	-	PAX2 PAX5 PAX8	6.06e-03	218	32	3	1.10.10.10
Domain	CH	FLNB FLNC	6.39e-03	70	32	2	PF00307
Domain	Filament	NEFM SYNM	6.57e-03	71	32	2	SM01391
Domain	-	FLNB FLNC	6.57e-03	71	32	2	1.10.418.10
Domain	IF	NEFM SYNM	6.75e-03	72	32	2	PS00226
Domain	CH	FLNB FLNC	6.93e-03	73	32	2	PS50021
Domain	Filament	NEFM SYNM	6.93e-03	73	32	2	PF00038
Domain	CH-domain	FLNB FLNC	7.30e-03	75	32	2	IPR001715
Domain	IF	NEFM SYNM	7.49e-03	76	32	2	IPR001664
Pathway	WP_ID_SIGNALING	PAX2 PAX5 PAX8	1.82e-06	16	22	3	M39359
Pathway	WP_ID_SIGNALING_PATHWAY	PAX2 PAX5 PAX8	6.17e-05	50	22	3	MM15817
Pathway	REACTOME_FORMATION_OF_INTERMEDIATE_MESODERM	PAX2 PAX8	6.47e-05	8	22	2	M48014
Pathway	WP_NPHP1_DELETION_SYNDROME	FLNB FLNC	1.27e-04	11	22	2	M48099
Pathway	REACTOME_FORMATION_OF_THE_NEPHRIC_DUCT	PAX2 PAX8	3.50e-04	18	22	2	M48242
Pubmed	PAX immunoreactivity in poorly differentiated small round cell tumors of childhood.	PAX2 PAX5 PAX8	7.78e-10	3	33	3	24897005
Pubmed	Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development.	PAX2 PAX5 PAX8	7.78e-10	3	33	3	1283313
Pubmed	Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding.	PAX2 PAX5 PAX8	3.11e-09	4	33	3	11134340
Pubmed	Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene.	PAX2 PAX5 PAX8	3.11e-09	4	33	3	8625814
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	PCNP TPR RPL24 FLNB SYNM AHNAK MPP7	3.91e-09	256	33	7	33397691
Pubmed	Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.	NEFM PAX2 PAX5 PAX8	3.97e-09	21	33	4	11500373
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	NEFM SRP14 TPR RPL24 FLNB IGLC7 AHNAK MDC1 SON	6.99e-09	652	33	9	31180492
Pubmed	Roles of Pax-genes in developing and adult brain as suggested by expression patterns.	PAX2 PAX5 PAX8	1.55e-08	6	33	3	8126546
Pubmed	Mapping of the human homologs of the murine paired-box-containing genes.	PAX2 PAX5 PAX8	1.55e-08	6	33	3	8431641
Pubmed	Pax2 contributes to inner ear patterning and optic nerve trajectory.	NEFM PAX2 PAX5	2.72e-08	7	33	3	8951055
Pubmed	Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8.	PAX2 PAX5 PAX8	4.34e-08	8	33	3	11704761
Pubmed	Pax genes in development.	PAX2 PAX5 PAX8	6.51e-08	9	33	3	7883790
Pubmed	Pax genes and their role in organogenesis.	PAX2 PAX5 PAX8	6.51e-08	9	33	3	10197584
Pubmed	Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9.	PAX2 PAX5 PAX8	6.51e-08	9	33	3	7981748
Pubmed	Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero.	PAX2 PAX5 PAX8	1.28e-07	11	33	3	35645295
Pubmed	Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer.	NEFM PAX2 PAX5	1.70e-07	12	33	3	16530751
Pubmed	Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord.	PAX2 PAX5 PAX8	2.21e-07	13	33	3	17166926
Pubmed	Pax: a murine multigene family of paired box-containing genes.	PAX2 PAX5 PAX8	3.51e-07	15	33	3	1685142
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	PCNP NEFM TMOD2 TPR DIP2B FLNB AHNAK	3.66e-07	498	33	7	36634849
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	PCNP TPR RPL24 MDC1	6.60e-07	72	33	4	31248990
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	SRP14 TPR FLNB AHNAK MDC1 SON	7.40e-07	340	33	6	29478914
Pubmed	A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum.	PAX2 PAX5 PAX8	7.46e-07	19	33	3	8575294
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	TPR DIP2B FLNB FLNC PDLIM5 SON	7.93e-07	344	33	6	30333137
Pubmed	Diffuse expression of PAX2 and PAX8 in the cystic epithelium of mixed epithelial stromal tumor, angiomyolipoma with epithelial cysts, and primary renal synovial sarcoma: evidence supporting renal tubular differentiation.	PAX2 PAX8	8.73e-07	2	33	2	21836481
Pubmed	Flat pattern of nephrogenic adenoma: previously unrecognized pattern unveiled using PAX2 and PAX8 immunohistochemistry.	PAX2 PAX8	8.73e-07	2	33	2	23328975
Pubmed	PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis.	PAX2 PAX8	8.73e-07	2	33	2	35387670
Pubmed	Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.	PAX2 PAX8	8.73e-07	2	33	2	8413205
Pubmed	PAX2 and PAX8 expression in primary and metastatic renal tumors: a comprehensive comparison.	PAX2 PAX8	8.73e-07	2	33	2	23194047
Pubmed	Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury preventing transition to chronic kidney disease.	PAX2 PAX8	8.73e-07	2	33	2	37977366
Pubmed	Utility of PAX8 and PAX2 immunohistochemistry in the identification of renal cell carcinoma in diagnostic cytology.	PAX2 PAX8	8.73e-07	2	33	2	22807381
Pubmed	Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.	PAX2 PAX5	8.73e-07	2	33	2	10662641
Pubmed	PAX2 and PAX8 expression in primary and metastatic müllerian epithelial tumors: a comprehensive comparison.	PAX2 PAX8	8.73e-07	2	33	2	21989345
Pubmed	Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland.	PAX2 PAX8	8.73e-07	2	33	2	1723950
Pubmed	A subset of solitary fibrous tumors express nuclear PAX8 and PAX2: a potential diagnostic pitfall.	PAX2 PAX8	8.73e-07	2	33	2	26404914
Pubmed	PAX2 and PAX8: useful markers for metastatic effusions.	PAX2 PAX8	8.73e-07	2	33	2	24334997
Pubmed	The utility of PAX8 in comparison with PAX5 immunohistochemical staining in the diagnosis of Hodgkin lymphoma.	PAX5 PAX8	8.73e-07	2	33	2	35926290
Pubmed	PAX8 and PAX2 immunostaining facilitates the diagnosis of primary epithelial neoplasms of the male genital tract.	PAX2 PAX8	8.73e-07	2	33	2	21934480
Pubmed	Identification of two promoters for human D-amino acid oxidase gene: implication for the differential promoter regulation mediated by PAX5/PAX2.	PAX2 PAX5	8.73e-07	2	33	2	25500505
Pubmed	The limits of promiscuity: isoform-specific dimerization of filamins.	FLNB FLNC	8.73e-07	2	33	2	12525170
Pubmed	Paired box genes, PAX-2 and PAX-8, are not frequently mutated in Wilms tumor.	PAX2 PAX8	8.73e-07	2	33	2	16814811
Pubmed	PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors.	PAX2 PAX8	8.73e-07	2	33	2	1337742
Pubmed	PAX8 and PAX5 are differentially expressed in B-cell and T-cell lymphomas.	PAX5 PAX8	8.73e-07	2	33	2	23163626
Pubmed	Diagnostic utility of PAX2 and PAX5 in distinguishing non-small cell lung cancer from small cell lung cancer.	PAX2 PAX5	8.73e-07	2	33	2	26823795
Pubmed	PAX8 and PAX2 expression in endocervical adenocarcinoma in situ and high-grade squamous dysplasia.	PAX2 PAX8	8.73e-07	2	33	2	23202787
Pubmed	A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.	FLNB FLNC	8.73e-07	2	33	2	9694715
Pubmed	PAX2 and PAX8 reliably distinguishes ovarian serous tumors from mucinous tumors.	PAX2 PAX8	8.73e-07	2	33	2	24992169
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TPR FLNB FLNC SYNM PDLIM5 AHNAK	1.03e-06	360	33	6	33111431
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	TPR FLNC PDLIM5 AHNAK MDC1 SON	1.87e-06	399	33	6	35987950
Pubmed	Characterization of a novel Lbx1 mouse loss of function strain.	PAX2 PAX5 PAX8	1.99e-06	26	33	3	34906895
Pubmed	Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.	PAX2 PAX5 PAX8	1.99e-06	26	33	3	21303848
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NEFM TPR FLNB FLNC AHNAK MDC1 SON	2.23e-06	653	33	7	22586326
Pubmed	Evaluation of putative renal cell carcinoma markers PAX-2, PAX-8, and hKIM-1 in germ cell tumors: a tissue microarray study of 100 cases.	PAX2 PAX8	2.62e-06	3	33	2	22495365
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNB FLNC	2.62e-06	3	33	2	11252955
Pubmed	Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.	PAX5 PAX8	2.62e-06	3	33	2	1516825
Pubmed	Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage.	PAX2 PAX8	2.62e-06	3	33	2	17047028
Pubmed	Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney.	PAX2 PAX8	2.62e-06	3	33	2	32381599
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNB FLNC	2.62e-06	3	33	2	12393796
Pubmed	Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1.	FLNC IGFN1	2.62e-06	3	33	2	20206623
Pubmed	Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors.	PAX2 PAX8	2.62e-06	3	33	2	7856737
Pubmed	Diagnostic Utility of Pax8, Pax2, and NGFR Immunohistochemical Expression in Pediatric Renal Tumors.	PAX2 PAX8	2.62e-06	3	33	2	28426529
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNB FLNC	2.62e-06	3	33	2	11153914
Pubmed	Pax2.1 is required for the development of thyroid follicles in zebrafish.	PAX2 PAX8	2.62e-06	3	33	2	12117823
Pubmed	PAX2(-)/PAX8(-)/inhibin A(+) immunoprofile in hemangioblastoma: A helpful combination in the differential diagnosis with metastatic clear cell renal cell carcinoma to the central nervous system.	PAX2 PAX8	2.62e-06	3	33	2	21263247
Pubmed	PAX2, PAX8 and CDX2 Expression in Metastatic Mucinous, Primary Ovarian Mucinous and Seromucinous Tumors and Review of the Literature.	PAX2 PAX8	2.62e-06	3	33	2	26797858
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PCNP SRP14 TPR KAT5 AHNAK MDC1 SON CFDP1	3.69e-06	1014	33	8	32416067
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	SRP14 TPR RPL24 FLNB FLNC PDLIM5 AHNAK	3.76e-06	707	33	7	19738201
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SRP14 TPR RPL24 FLNB PDLIM5 AHNAK MPP7	3.79e-06	708	33	7	39231216
Pubmed	Value of PAX8, PAX2, claudin-4, and h-caldesmon immunostaining in distinguishing peritoneal epithelioid mesotheliomas from serous carcinomas.	PAX2 PAX8	5.23e-06	4	33	2	23196794
Pubmed	Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.	PAX2 PAX5	5.23e-06	4	33	2	10934015
Pubmed	Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear.	NEFM PAX2	5.23e-06	4	33	2	11793341
Pubmed	Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice.	PAX2 PAX8	5.23e-06	4	33	2	28160066
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNB FLNC	5.23e-06	4	33	2	11739414
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB FLNC	5.23e-06	4	33	2	22802962
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	TPR RPL24 FLNB FLNC PDLIM5 AHNAK	6.37e-06	494	33	6	26831064
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	TMOD2 TPR FLNB MDC1 SON CFDP1	7.31e-06	506	33	6	30890647
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	SRP14 TPR RPL24 NLRP1 FLNB	8.29e-06	295	33	5	26209609
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB FLNC	8.72e-06	5	33	2	19366992
Pubmed	Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1.	PAX2 PAX5	8.72e-06	5	33	2	7577673
Pubmed	Filamin C interacts with the muscular dystrophy KY protein and is abnormally distributed in mouse KY deficient muscle fibres.	FLNC IGFN1	8.72e-06	5	33	2	15385448
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNB FLNC	8.72e-06	5	33	2	12006559
Pubmed	Value of PAX8, PAX2, napsin A, carbonic anhydrase IX, and claudin-4 immunostaining in distinguishing pleural epithelioid mesothelioma from metastatic renal cell carcinoma.	PAX2 PAX8	8.72e-06	5	33	2	23503645
Pubmed	The oncogenic potential of Pax genes.	PAX2 PAX8	8.72e-06	5	33	2	8099544
Pubmed	Different expression of synemin isoforms in glia and neurons during nervous system development.	NEFM SYNM	8.72e-06	5	33	2	16817202
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNB FLNC	8.72e-06	5	33	2	17360453
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NEFM SRP14 TPR RPL24 FLNB FLNC PDLIM5 AHNAK	9.21e-06	1149	33	8	35446349
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	PCNP SRP14 RPL24 FLNB SYNM AHNAK	1.03e-05	538	33	6	28524877
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	FLNB FLNC AHNAK	1.15e-05	46	33	3	33403043
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PCNP NEFM TPR PDLIM5 AHNAK MDC1	1.16e-05	549	33	6	38280479
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	NEFM SRP14 TPR RPL24 FLNB FLNC AHNAK	1.19e-05	844	33	7	25963833
Pubmed	Molecular genetics of the Pax gene family.	PAX2 PAX8	1.31e-05	6	33	2	1485966
Pubmed	Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.	PAX2 PAX5	1.31e-05	6	33	2	22308434
Pubmed	Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin.	NEFM PAX2	1.31e-05	6	33	2	17196957
Pubmed	Immunohistochemical distinction of renal cell carcinoma from other carcinomas with clear-cell histomorphology: utility of CD10 and CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin.	PAX2 PAX8	1.31e-05	6	33	2	25279712
Pubmed	Nephric lineage specification by Pax2 and Pax8.	PAX2 PAX8	1.31e-05	6	33	2	12435636
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	PCNP TPR FLNB FLNC PDLIM5 AHNAK	1.41e-05	568	33	6	37774976
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	TPR DIP2B FLNB AHNAK MDC1	1.47e-05	332	33	5	32786267
Pubmed	Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.	PAX2 PAX5	1.83e-05	7	33	2	9405645
Pubmed	Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4.	PAX2 PAX8	1.83e-05	7	33	2	7990960
Pubmed	A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.	PAX2 PAX8	1.83e-05	7	33	2	7590254
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNB FLNC	1.83e-05	7	33	2	16076904
Interaction	PHLPP1 interactions	PCNP TPR RPL24 FLNB SYNM AHNAK MPP7	7.45e-07	333	32	7	int:PHLPP1
Interaction	DCPS interactions	SRP14 TPR FLNB GPC5 AHNAK MDC1 SON	2.28e-06	394	32	7	int:DCPS
Interaction	NSD2 interactions	PCNP SRP14 TPR RPL24 KAT5 MDC1	4.38e-06	278	32	6	int:NSD2
Interaction	CIT interactions	NEFM TMOD2 SRP14 TPR RPL24 FLNB FLNC PAX8 AHNAK MDC1 SON	8.09e-06	1450	32	11	int:CIT
Interaction	PRC1 interactions	TMOD2 SRP14 TPR RPL24 FLNB FLNC AHNAK MDC1 SON	1.41e-05	973	32	9	int:PRC1
Interaction	DNTTIP1 interactions	NEFM PAX2 PAX8 MDC1	1.51e-05	95	32	4	int:DNTTIP1
Interaction	ID2 interactions	PAX2 PAX5 PAX8 CFDP1	2.24e-05	105	32	4	int:ID2
Interaction	MIDEAS interactions	PAX2 PAX8 PDLIM5 MDC1	2.50e-05	108	32	4	int:MIDEAS
Interaction	KIF20A interactions	NEFM TMOD2 SRP14 RPL24 FLNB FLNC AHNAK MDC1 SON	2.62e-05	1052	32	9	int:KIF20A
Interaction	KY interactions	FLNC IGFN1	3.65e-05	6	32	2	int:KY
Interaction	USP25 interactions	RPL24 FLNC IGFN1 SON	4.72e-05	127	32	4	int:USP25
Interaction	ITGB2 interactions	TPR FLNB FLNC SON	5.48e-05	132	32	4	int:ITGB2
Interaction	TNIP1 interactions	PCNP NEFM SRP14 TPR RPL24 FLNB AHNAK MDC1 SON	8.20e-05	1217	32	9	int:TNIP1
Interaction	PTPN4 interactions	TPR KAT5 MPP7	8.54e-05	54	32	3	int:PTPN4
Interaction	BRCA1 interactions	TPR RPL24 FLNB FLNC PAX2 KAT5 PDLIM5 AHNAK MDC1	1.00e-04	1249	32	9	int:BRCA1
Interaction	SNCA interactions	PCNP NEFM TMOD2 TPR DIP2B FLNB AHNAK	1.07e-04	716	32	7	int:SNCA
Interaction	SIRT7 interactions	NEFM TPR FLNB FLNC AHNAK MDC1 SON	1.36e-04	744	32	7	int:SIRT7
Interaction	ITGB3 interactions	TPR FLNB FLNC SON	1.46e-04	170	32	4	int:ITGB3
Interaction	ABCC12 interactions	NEFM TPR	1.60e-04	12	32	2	int:ABCC12
Interaction	ARID1B interactions	PAX2 KAT5 PAX8 MDC1	1.71e-04	177	32	4	int:ARID1B
Interaction	PLOD2 interactions	TPR RPL24 FLNB FLNC	1.82e-04	180	32	4	int:PLOD2
Interaction	NKX2-4 interactions	PAX2 PAX8	1.88e-04	13	32	2	int:NKX2-4
Interaction	MORC4 interactions	PAX2 PAX8 AHNAK	2.18e-04	74	32	3	int:MORC4
Interaction	FBXO43 interactions	FLNB FLNC AHNAK	2.18e-04	74	32	3	int:FBXO43
Interaction	YAP1 interactions	PCNP NEFM TPR RPL24 FLNB PDLIM5 AHNAK MDC1	2.42e-04	1095	32	8	int:YAP1
Interaction	SSH1 interactions	NEFM TMOD2 FLNC	2.65e-04	79	32	3	int:SSH1
Interaction	UHRF2 interactions	PCNP TPR KAT5 AHNAK	2.72e-04	200	32	4	int:UHRF2
Interaction	POU5F1 interactions	SRP14 TPR RPL24 FLNB AHNAK MDC1	2.75e-04	584	32	6	int:POU5F1
Interaction	SUMO2 interactions	TPR DIP2B FLNB SELENBP1 AHNAK MDC1	2.93e-04	591	32	6	int:SUMO2
Interaction	FN1 interactions	SRP14 TPR RPL24 FLNB FLNC PDLIM5 AHNAK	3.05e-04	848	32	7	int:FN1
Interaction	KCNA3 interactions	SRP14 TPR RPL24 FLNB PDLIM5 AHNAK MPP7	3.59e-04	871	32	7	int:KCNA3
Interaction	OFCC1 interactions	FLNC SELENBP1	3.68e-04	18	32	2	int:OFCC1
Interaction	ECT2 interactions	TMOD2 RPL24 FLNB FLNC AHNAK MDC1 SON	4.00e-04	887	32	7	int:ECT2
Interaction	H3C1 interactions	SRP14 TPR PAX5 KAT5 AHNAK MDC1 CFDP1	4.40e-04	901	32	7	int:H3C1
Interaction	LONRF1 interactions	PAX5 KAT5 PAX8	6.45e-04	107	32	3	int:LONRF1
Interaction	HSPB7 interactions	FLNB FLNC	6.60e-04	24	32	2	int:HSPB7
Interaction	DTX3 interactions	FLNB FLNC AHNAK	6.63e-04	108	32	3	int:DTX3
Interaction	ACTC1 interactions	TMOD2 TPR FLNB MDC1 SON CFDP1	6.88e-04	694	32	6	int:ACTC1
Interaction	FOXP1 interactions	SRP14 PAX2 PAX8 HYDIN	6.91e-04	256	32	4	int:FOXP1
Interaction	PAX8 interactions	PAX2 PAX5 PAX8	7.18e-04	111	32	3	int:PAX8
Interaction	NAA40 interactions	PCNP TPR RPL24 PDLIM5 AHNAK SON CFDP1	7.18e-04	978	32	7	int:NAA40
Cytoband	3q12.3	PCNP ERVK-5	5.97e-05	16	33	2	3q12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr3q12	PCNP RPL24	7.00e-04	54	33	2	chr3q12
Cytoband	Ensembl 112 genes in cytogenetic band chr10p12	EBLN1 MPP7	4.58e-03	140	33	2	chr10p12
GeneFamily	Paired boxes	PAX2 PAX5 PAX8	1.31e-07	9	22	3	675
GeneFamily	Intermediate filaments Type IV	NEFM SYNM	2.11e-05	6	22	2	611
GeneFamily	PRD class homeoboxes and pseudogenes	PAX2 PAX5 PAX8	1.83e-04	92	22	3	521
GeneFamily	PDZ domain containing	PDLIM5 AHNAK MPP7	7.98e-04	152	22	3	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	TMIGD1 IGFN1	1.62e-02	161	22	2	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	HYDIN PCIF1	2.02e-02	181	22	2	694
Coexpression	DESCARTES_FETAL_EYE_ASTROCYTES	PAX2 PAX5 PAX8	1.33e-05	39	31	3	M40188
Coexpression	GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP	SYNM TMEM132B MPP7 PCIF1	7.83e-05	194	31	4	M4187
Coexpression	LAKE_ADULT_KIDNEY_C12_THICK_ASCENDING_LIMB	SRP14 RPL24 FLNB GPC5 SELENBP1	7.87e-05	381	31	5	M39231
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN	TPR AHNAK MDC1 PCIF1	8.81e-05	200	31	4	M5980
Coexpression	CAMP_UP.V1_UP	DIP2B NLRP1 KAT5 SELENBP1	8.81e-05	200	31	4	M2720
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	NEFM GPC5 SYNM AHNAK	1.06e-04	210	31	4	M2010
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	NEFM GPC5 SYNM AHNAK	1.21e-04	217	31	4	MM861
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IGFN1 GPC5 SELENBP1 PDLIM5 AHNAK	2.16e-07	187	32	5	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC PAX2 SYNM PAX8	7.81e-06	178	32	4	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 PAX8 TMEM132B HYDIN	7.81e-06	178	32	4	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 PAX8 TMEM132B HYDIN	7.81e-06	178	32	4	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 PAX8 TMEM132B HYDIN	7.81e-06	178	32	4	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNB FLNC SYNM MPP7	8.71e-06	183	32	4	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	9.49e-06	187	32	4	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	9.49e-06	187	32	4	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	9.49e-06	187	32	4	93c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	9.49e-06	187	32	4	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	9.49e-06	187	32	4	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	1.07e-05	193	32	4	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 PDLIM5 AHNAK	1.07e-05	193	32	4	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRP14 TPR SON CFDP1	1.10e-05	194	32	4	8985095f291c1b54e45f4edece49aa26e8c8b732
ToppCell	LAM-Endothelial-LymEndo\|Endothelial / Condition, Lineage and Cell class	FLNC SYNM AHNAK MPP7	1.19e-05	198	32	4	ba64b1c95dfaa995045239d412e725596f6c482e
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	SRP14 RPL24 AHNAK SON	1.19e-05	198	32	4	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Lymphatic\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	TMOD2 FLNC SYNM MPP7	1.21e-05	199	32	4	88f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMOD2 FLNC SYNM MPP7	1.21e-05	199	32	4	64b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMOD2 FLNC SYNM MPP7	1.21e-05	199	32	4	2b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ADH7 SELENBP1 AHNAK CFDP1	1.24e-05	200	32	4	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	droplet-Liver-LIVER_NPC-30m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB SELENBP1 PAX8	1.34e-04	139	32	3	e363c69b58cff8571ca75b91a3d052f9cbccac27
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SYNM HYDIN MPP7	1.46e-04	143	32	3	ce045ec7c311a1797ae562bec114f9e90604d063
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-B_cells\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	PAX2 PAX5 IGLC7	1.52e-04	145	32	3	34cff6df39ff05995041f0c231c60a50ad1a0c1c
ToppCell	RV-16._Neuronal\|World / Chamber and Cluster_Paper	TMOD2 TMEM132B AHNAK	1.65e-04	149	32	3	3a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEFM RPL24 GPC5	1.71e-04	151	32	3	f8ae05667a1db58a94be0f4e0b538bf80eb6b347
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEFM RPL24 GPC5	1.71e-04	151	32	3	7bc78aba6ab379d6eb00d4cf1843f532dfd4ce4e
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	PAX2 PAX5 IGLC7	1.74e-04	152	32	3	66f9190de155251a63a7a669374f342a75d22ea0
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	SYNM PDLIM5 MPP7	1.78e-04	153	32	3	ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFN1 PAX8 SON	2.30e-04	167	32	3	b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCell	LA-16._Neuronal\|World / Chamber and Cluster_Paper	TMOD2 TMEM132B AHNAK	2.34e-04	168	32	3	2fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	TMOD2 TMEM132B AHNAK	2.34e-04	168	32	3	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAX2 PAX8 HYDIN	2.34e-04	168	32	3	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	droplet-Fat-Gat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 TMEM132B HYDIN	2.55e-04	173	32	3	a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCell	droplet-Fat-Gat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 TMEM132B HYDIN	2.55e-04	173	32	3	f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL24 FLNC HYDIN	2.55e-04	173	32	3	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	droplet-Fat-Gat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX2 TMEM132B HYDIN	2.55e-04	173	32	3	f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL24 FLNC HYDIN	2.55e-04	173	32	3	649b08a409095592cccf31883be69c754411280d
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL24 FLNC HYDIN	2.60e-04	174	32	3	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IGFN1 SELENBP1 AHNAK	2.60e-04	174	32	3	53c2c132566a7682f3268c7f9138700f09c3b94d
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAX2 PAX8 MPP7	2.69e-04	176	32	3	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMIGD1 SELENBP1 AHNAK	2.69e-04	176	32	3	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMOD2 NLRP1 PAX5	2.73e-04	177	32	3	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMOD2 NLRP1 PAX5	2.73e-04	177	32	3	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMOD2 NLRP1 PAX5	2.73e-04	177	32	3	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	(06)_Krt4/13+\|World / shred by cell type and Timepoint	ADH7 SELENBP1 AHNAK	2.78e-04	178	32	3	46efdf03aa1317bc600138e871509b995e773cce
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAX2 PAX8 HYDIN	2.78e-04	178	32	3	544379f5a6145429762258d426b876bb36c112f5
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADH7 TMIGD1 FLNC	2.78e-04	178	32	3	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADH7 TMIGD1 FLNC	2.78e-04	178	32	3	d348a9550db940d204706529759dc51e30506b5f
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMOD2 PAX5 TMEM132B	2.82e-04	179	32	3	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	ADH7 SYNM MPP7	2.82e-04	179	32	3	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	Neuroendocrine-neuroendo-1\|World / Class top	TMOD2 PAX2 IGFN1	2.87e-04	180	32	3	50fdd182a083380899b5943cb5f55ffd77e2a7d4
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	TMOD2 TMEM132B AHNAK	2.87e-04	180	32	3	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	SELENBP1 SYNM SON	2.87e-04	180	32	3	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX8 TMEM132B HYDIN	2.91e-04	181	32	3	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	FLNC SYNM MPP7	2.91e-04	181	32	3	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	TMOD2 TMEM132B AHNAK	2.91e-04	181	32	3	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX8 TMEM132B HYDIN	2.91e-04	181	32	3	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	2.91e-04	181	32	3	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAX8 TMEM132B HYDIN	2.91e-04	181	32	3	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	FLNC SYNM MPP7	2.91e-04	181	32	3	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	FLNB GPC5 IGLC7	3.01e-04	183	32	3	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PAX2 PAX8 HYDIN	3.01e-04	183	32	3	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPC5 SELENBP1 MPP7	3.01e-04	183	32	3	6847c1252d6bb105524f812658112517fd351eab
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNB SYNM PDLIM5	3.06e-04	184	32	3	39168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCell	Endothelial-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FLNB FLNC SYNM	3.11e-04	185	32	3	133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENBP1 PDLIM5 AHNAK	3.16e-04	186	32	3	41e03be964044dae690d566bd078dab3d8045eba
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	3.16e-04	186	32	3	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	3.16e-04	186	32	3	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	3.26e-04	188	32	3	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC SYNM MPP7	3.26e-04	188	32	3	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADH7 TMOD2 HYDIN	3.26e-04	188	32	3	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	Club-club-5\|World / Class top	ADH7 SELENBP1 AHNAK	3.26e-04	188	32	3	5911409108ececdb4f8112ec4bacc215e204001f
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FLNC SYNM MPP7	3.26e-04	188	32	3	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNC SYNM MPP7	3.26e-04	188	32	3	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	wk_15-18-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TMOD2 SYNM MPP7	3.31e-04	189	32	3	f0418851ad4042c4cd87c8729e4f0d43bdf8fccb
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNC SYNM MPP7	3.31e-04	189	32	3	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	3.31e-04	189	32	3	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC PAX2 PAX8	3.31e-04	189	32	3	319e42f6e2322208de78bc666fb2c074707eb4da
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 MPP7	3.36e-04	190	32	3	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 GPC5 PAX8	3.36e-04	190	32	3	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	FLNC SYNM MPP7	3.36e-04	190	32	3	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 AHNAK	3.36e-04	190	32	3	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 AHNAK	3.36e-04	190	32	3	b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC PAX2 PAX8	3.36e-04	190	32	3	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GPC5 SELENBP1 MPP7	3.36e-04	190	32	3	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 GPC5 PAX8	3.36e-04	190	32	3	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPC5 SELENBP1 AHNAK	3.36e-04	190	32	3	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	wk_20-22-Endothelial-Lymph_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FLNC SYNM MPP7	3.41e-04	191	32	3	631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	Healthy_Control-Epithelial-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	15b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAX2 PAX8 HYDIN	3.41e-04	191	32	3	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPC5 SELENBP1 MPP7	3.41e-04	191	32	3	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Healthy_Control-Epithelial-Epithelial-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	28caedb2e448e0c7f494100d714fa7cdcf150691
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB PAX5 IGLC7	3.41e-04	191	32	3	6a8b0987e75456a257954288206da0032605ff2a
ToppCell	Healthy_Control-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADH7 SELENBP1 HYDIN	3.41e-04	191	32	3	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	GPC5 SELENBP1 MPP7	3.41e-04	191	32	3	276455a64c2c3503d5048615762eb2ee37f0ac70
Drug	hydroxyflutamide	ADH7 KAT5 SELENBP1 PDLIM5	9.89e-06	103	30	4	CID000091649
Drug	chloroacetonitrile	NLRP1 SYNM	1.67e-05	5	30	2	CID000007856
Drug	HTHQ	NLRP1 SYNM	6.01e-05	9	30	2	CID000119193
Drug	N-methyl-N'-nitrosourea	NLRP1 SYNM	6.01e-05	9	30	2	CID000114836
Drug	1,2-diethylbenzene	NEFM NLRP1	7.50e-05	10	30	2	CID000008657
Drug	amphetaminil	PCNP KAT5	7.50e-05	10	30	2	CID000028615
Drug	1,2-diacetylbenzene	NEFM NLRP1	7.50e-05	10	30	2	CID000035459
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; PC3; HT_HG-U133A	PAX2 PAX8 PDLIM5 AHNAK	1.02e-04	187	30	4	4589_UP
Drug	Lansoprazole [103577-45-3]; Down 200; 10.8uM; HL60; HT_HG-U133A	NLRP1 PAX8 AHNAK PCIF1	1.06e-04	189	30	4	2967_DN
Drug	Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	TMOD2 PAX2 PDLIM5 AHNAK	1.18e-04	194	30	4	3846_UP
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A	TPR PAX2 PAX5 PDLIM5	1.18e-04	194	30	4	4798_UP
Drug	Guanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HT_HG-U133A	NEFM KAT5 PDLIM5 AHNAK	1.18e-04	194	30	4	4642_UP
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A	NEFM PAX2 PAX5 PAX8	1.25e-04	197	30	4	4266_UP
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT_HG-U133A	PAX2 PAX5 PAX8 PDLIM5	1.27e-04	198	30	4	4214_UP
Drug	Trimipramine maleate salt [521-78-8]; Up 200; 9.8uM; HL60; HT_HG-U133A	NLRP1 PAX5 SYNM PDLIM5	1.27e-04	198	30	4	3004_UP
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A	KAT5 PDLIM5 AHNAK PCIF1	1.30e-04	199	30	4	2165_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; HL60; HT_HG-U133A	NLRP1 FLNC SYNM PAX8	1.30e-04	199	30	4	2683_UP
Drug	Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; HL60; HT_HG-U133A	NEFM TMOD2 NLRP1 PAX5	1.32e-04	200	30	4	2719_UP
Drug	Delsoline [509-18-2]; Up 200; 8.6uM; MCF7; HT_HG-U133A	NEFM NLRP1 PAX5 PAX8	1.32e-04	200	30	4	6075_UP
Drug	M-Hb	PAX2 PAX5 PAX8	1.41e-04	77	30	3	CID006122542
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNB FLNC	3.42e-06	3	32	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNB FLNC	3.42e-06	3	32	2	DOID:0111190 (implicated_via_orthology)
Disease	myopathy (implicated_via_orthology)	FLNB FLNC PDLIM5	1.94e-05	48	32	3	DOID:423 (implicated_via_orthology)
Disease	congenital hypothyroidism (implicated_via_orthology)	NEFM PAX8	1.03e-04	14	32	2	DOID:0050328 (implicated_via_orthology)
Disease	spine bone mineral density	GPC5 KAT5 MPP7	2.91e-04	119	32	3	EFO_0007701
Disease	eating disorder	ADH7 FLNB	5.54e-04	32	32	2	EFO_0005203
Disease	smoking status measurement, diastolic blood pressure	NLRP1 KAT5 CFDP1	6.79e-04	159	32	3	EFO_0006336, EFO_0006527
Disease	cervical cancer	GPC5 PAX8	8.66e-04	40	32	2	MONDO_0002974
Disease	free cholesterol to total lipids in IDL percentage	KAT5 PCIF1	1.00e-03	43	32	2	EFO_0022278
Disease	cholesteryl esters to total lipids in large VLDL percentage	KAT5 PCIF1	1.69e-03	56	32	2	EFO_0022250
Disease	factor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement	ADH7 DIP2B	1.69e-03	56	32	2	EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Disease	free cholesterol to total lipids in medium VLDL percentage	KAT5 PCIF1	1.75e-03	57	32	2	EFO_0022284
Disease	fibrinogen measurement, factor VII measurement	ADH7 DIP2B	1.81e-03	58	32	2	EFO_0004619, EFO_0004623
Disease	phospholipids:total lipids ratio	ADH7 KAT5 PCIF1	1.89e-03	227	32	3	EFO_0020946

Protein segments in the cluster

Peptide	Gene	Start	Entry
EGVTTVKPGDKVIPL	ADH7	91	P40394
GKVKVPEVDVRGPKV	AHNAK	596	Q09666
GPKVKGDVDVSVPKV	AHNAK	1206	Q09666
LKGPKVKGDVDVSVP	AHNAK	1931	Q09666
GPKVKGDVDVSLPKV	AHNAK	4396	Q09666
PKVDVKGPKVGIDTP	AHNAK	4551	Q09666
PKVKGDFDVSVPKVE	AHNAK	4861	Q09666
IGGSKPKVATPKVVE	PAX8	76	Q06710
GVIGGSKPKVATPKV	PAX5	81	Q02548
TAEKPGKEEDVVTPK	MDC1	1846	Q14676
SGNPEVKVKGIDPVI	GPC5	441	P78333
ELSKVEGKTGTPEKP	KAT5	391	Q92993
KDVVDPSKVKIAGPG	FLNB	1416	O75369
GGPEEEAEKPVKTKT	PCNP	21	Q8WW12
GPTGPVATEVVDKEK	NLRP1	1081	Q9C000
VTVKGPKGTEEPVKV	FLNC	511	Q14315
PVKDVVDPGKVKCSG	FLNC	1436	Q14315
IIPGSKEETPSKEGK	MPP7	216	Q5T2T1
GVKVVIVNPETKGPV	DIP2B	1371	Q9P265
QKGEPKEVVKPVPIT	PDLIM5	96	Q96HC4
GVIGGSKPKVATPKV	PAX2	81	Q02962
IKPLKGKVPAGVDVI	ERVK-5	491	Q9HDB9
PQPGIGDVKVIEKAT	EBLN1	46	P0CF75
KVPPSTQVKKGEETE	CFDP1	126	Q9UEE9
SKEVILPIKVVGGPT	HYDIN	1671	Q4G0P3
SGNGVKKPKIEIPVT	PCIF1	121	Q9H4Z3
GSPVKVGVETTKPSK	IGLC7	46	A0M8Q6
EPLVVKAGKPVIVKI	IGFN1	556	Q86VF2
GVVPVGTEEAPKVFK	TMEM126B	16	Q8IUX1
LTGKPVSVPVKVVGV	TMEM132B	436	Q14DG7
GAVGEKVVKPLDVPA	SYNM	881	O15061
SVEKVIQVPPKKVKG	SELENBP1	286	Q13228
IVKDKTVGVPIEPII	TMIGD1	211	Q6UXZ0
KIVKPVKVSAPRVGG	RPL24	141	P83731
RTKPIPKKGTVEGFE	SRP14	36	P37108
PKKLKSVTPVGTEEE	TPR	1856	P12270
GPVRNVVKGEKVKPV	TMOD2	161	Q9NZR1
VVKGEKVKPVFEEPP	TMOD2	166	Q9NZR1
PPTIEEKVAKKSGGA	SON	2086	P18583
VEEKGKSPVSKSPVE	NEFM	661	P07197