Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell fate specification

TBX3 EHMT2 POU4F1 CHD4 GATAD2B TBX2

1.03e-05123836GO:0001708
GeneOntologyBiologicalProcessureteric peristalsis

TBX3 TBX2

4.79e-053832GO:0072105
GeneOntologyBiologicalProcessureter smooth muscle contraction

TBX3 TBX2

4.79e-053832GO:0014849
GeneOntologyBiologicalProcessmammary placode formation

TBX3 TBX2

9.55e-054832GO:0060596
GeneOntologyCellularComponentCHD-type complex

CHD5 CHD4 GATAD2B

3.94e-0517833GO:0090545
GeneOntologyCellularComponentNuRD complex

CHD5 CHD4 GATAD2B

3.94e-0517833GO:0016581
GeneOntologyCellularComponentnuclear body

TCF20 EHMT2 ORC3 CLK3 ABRAXAS1 CHD5 MKI67 EXO1 NFKBIZ POU4F2 KMT2E CHTOP GATAD2B

5.37e-059038313GO:0016604
GeneOntologyCellularComponentnuclear speck

EHMT2 CLK3 CHD5 NFKBIZ POU4F2 KMT2E CHTOP GATAD2B

3.13e-04431838GO:0016607
GeneOntologyCellularComponenthistone deacetylase complex

CHD5 CHD4 KMT2E GATAD2B

3.66e-0485834GO:0000118
DomainTBX

TBX3 TBX2

1.86e-052812IPR022582
DomainTBX

TBX3 TBX2

1.86e-052812PF12598
DomainCHDCT2

CHD5 CHD4

5.56e-053812PF08074
DomainCHDNT

CHD5 CHD4

5.56e-053812PF08073
DomainDUF1086

CHD5 CHD4

5.56e-053812IPR009462
DomainDUF1087

CHD5 CHD4

5.56e-053812IPR009463
DomainCHD_N

CHD5 CHD4

5.56e-053812IPR012958
DomainCHD_C2

CHD5 CHD4

5.56e-053812IPR012957
DomainDUF1087

CHD5 CHD4

5.56e-053812PF06465
DomainDUF1086

CHD5 CHD4

5.56e-053812PF06461
DomainDUF1087

CHD5 CHD4

5.56e-053812SM01147
DomainDUF1086

CHD5 CHD4

5.56e-053812SM01146
DomainPI3kinase_P85

PIK3R1 DAPP1

1.84e-045812IPR001720
DomainZnf_FYVE_PHD

PIKFYVE TCF20 CHD5 CHD4 KMT2E

4.47e-04147815IPR011011
DomainDNA/RNA_helicase_DEAH_CS

CHD5 CHD4 DHX30

4.65e-0435813IPR002464
DomainDC

DCDC1 RP1L1

5.11e-048812PS50309
DomainDoublecortin_dom

DCDC1 RP1L1

5.11e-048812IPR003533
DomainDEAH_ATP_HELICASE

CHD5 CHD4 DHX30

5.94e-0438813PS00690
DomainPHD

TCF20 CHD5 CHD4 KMT2E

6.06e-0489814SM00249
DomainZnf_PHD

TCF20 CHD5 CHD4 KMT2E

6.59e-0491814IPR001965
DomainZF_PHD_2

TCF20 CHD5 CHD4 KMT2E

7.75e-0495814PS50016
DomainZF_PHD_1

TCF20 CHD5 CHD4 KMT2E

8.06e-0496814PS01359
DomainHelicase_C

CHD5 CHD4 DDX27 DHX30

1.21e-03107814PF00271
DomainHELICc

CHD5 CHD4 DDX27 DHX30

1.21e-03107814SM00490
DomainHelicase_C

CHD5 CHD4 DDX27 DHX30

1.25e-03108814IPR001650
DomainHELICASE_CTER

CHD5 CHD4 DDX27 DHX30

1.29e-03109814PS51194
DomainHELICASE_ATP_BIND_1

CHD5 CHD4 DDX27 DHX30

1.29e-03109814PS51192
DomainDEXDc

CHD5 CHD4 DDX27 DHX30

1.29e-03109814SM00487
DomainHelicase_ATP-bd

CHD5 CHD4 DDX27 DHX30

1.34e-03110814IPR014001
DomainPOU

POU4F1 POU4F2

2.14e-0316812SM00352
DomainPOU_2

POU4F1 POU4F2

2.14e-0316812PS00465
DomainPOU_dom

POU4F1 POU4F2

2.14e-0316812IPR000327
DomainPOU_3

POU4F1 POU4F2

2.14e-0316812PS51179
DomainPou

POU4F1 POU4F2

2.14e-0316812PF00157
DomainPOU_1

POU4F1 POU4F2

2.14e-0316812PS00035
DomainTF_T-box

TBX3 TBX2

2.42e-0317812IPR001699
DomainTBOX

TBX3 TBX2

2.42e-0317812SM00425
DomainTF_T-box_CS

TBX3 TBX2

2.42e-0317812IPR018186
Domain-

TBX3 TBX2

2.42e-03178122.60.40.820
DomainPOU

POU4F1 POU4F2

2.42e-0317812IPR013847
DomainTBOX_3

TBX3 TBX2

2.42e-0317812PS50252
DomainT-box

TBX3 TBX2

2.42e-0317812PF00907
DomainTBOX_1

TBX3 TBX2

2.42e-0317812PS01283
DomainTBOX_2

TBX3 TBX2

2.42e-0317812PS01264
DomainRhoGAP

PIK3R1 ARHGAP9 ARHGAP11A

2.47e-0362813SM00324
DomainRhoGAP

PIK3R1 ARHGAP9 ARHGAP11A

2.59e-0363813PF00620
DomainRHOGAP

PIK3R1 ARHGAP9 ARHGAP11A

2.71e-0364813PS50238
DomainRhoGAP_dom

PIK3R1 ARHGAP9 ARHGAP11A

2.71e-0364813IPR000198
Domain-

PIK3R1 ARHGAP9 ARHGAP11A

2.71e-03648131.10.555.10
DomainZinc_finger_PHD-type_CS

CHD5 CHD4 KMT2E

2.83e-0365813IPR019786
DomainPHD

CHD5 CHD4 KMT2E

4.24e-0375813PF00628
DomainChromo_domain

CHD5 CHD4

4.82e-0324812IPR023780
DomainZnf_PHD-finger

CHD5 CHD4 KMT2E

4.90e-0379813IPR019787
DomainChromo

CHD5 CHD4

5.64e-0326812PF00385
Domain-

POU4F1 POU4F2

6.08e-03278121.10.260.40
DomainCHROMO_1

CHD5 CHD4

6.53e-0328812PS00598
DomainCHROMO_2

CHD5 CHD4

6.53e-0328812PS50013
DomainFHA

FHAD1 MKI67

6.53e-0328812SM00240
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

EHMT2 EXO1 POU4F1 POU4F2 CHD4 GATAD2B

7.63e-05157646MM15226
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

EHMT2 EXO1 POU4F1 POU4F2 CHD4 GATAD2B

8.47e-05160646M27498
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

TAOK2 TDRKH RIF1 DST PNPLA6 EHMT2 RBM33 ORC3 CLK3 CHAF1A PNO1 HERC2 CTNND2 ZC3H7B DDX27 CHTOP GATAD2B DHX30 TBX2

2.80e-091497851931527615
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

RIF1 EHMT2 RBM33 CHAF1A MKI67 PNO1 CHD4 HERC2 DDX27 CHTOP GATAD2B

7.59e-08533851130554943
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PIKFYVE TDRKH DST ABCB10 RGPD8 EHMT2 RBM33 PIK3R1 EIF2B3 HERC2 CCDC115 ESPL1 GNL1 DDX27 MTRF1L CDKAL1 DHX30

1.07e-071496851732877691
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

TCF20 EHMT2 CHD5 MKI67 CHD4 GATAD2B

2.11e-0710385632744500
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PIKFYVE TCF20 RGPD8 RBM33 PROSER3 CHAF1A UGGT1 MID1 ESPL1 CHTOP GATAD2B CDKAL1

2.27e-07733851234672954
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

FLG KRT4 CHD5 BEND7 MKI67 PNO1 CHD4 DDX27 CHTOP GATAD2B DHX30

2.69e-07605851128977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RIF1 TCF20 EHMT2 ABRAXAS1 CHAF1A CHD5 MKI67 CHD4 HERC2 ARHGAP11A GATAD2B

2.82e-07608851136089195
Pubmed

A human MAP kinase interactome.

TBX3 RIF1 DST TCF20 RBM33 PIK3R1 KIAA0232 CHAF1A HERC2 DDX27

3.18e-07486851020936779
Pubmed

Comparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons.

MKI67 POU4F1 POU4F2

4.90e-07785324709358
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TBX3 RIF1 DST TCF20 EHMT2 ORC3 ABRAXAS1 CHAF1A MKI67 EXO1 CHD4 ARHGAP11A CHTOP GATAD2B CDKAL1

5.22e-071294851530804502
Pubmed

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system.

MKI67 POU4F1 POU4F2

1.17e-06985315716344
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RIF1 MKI67 EXO1 PNO1 CHD4 HERC2 ZC3H7B ESPL1 DDX27 CHTOP DHX30

2.45e-06759851135915203
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RIF1 TBC1D4 PNPLA6 TCF20 PRICKLE3 CHAF1A MKI67 EXO1 CHD4 ESPL1 GATAD2B

2.95e-06774851115302935
Pubmed

Insm1 promotes neurogenic proliferation in delaminated otic progenitors.

MKI67 POU4F1 POU4F2

3.05e-061285326545349
Pubmed

ISL1 regulates lung branching morphogenesis via Shh signaling pathway.

TBX3 MKI67 TBX2

3.05e-061285337442233
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TDRKH TBX3 PNPLA6 DCDC1 EHMT2 PIK3R1 CHAF1A CHD5 CHD4 CHTOP GATAD2B CDKAL1 TBX2

3.10e-061116851331753913
Pubmed

Brn3b regulates the formation of fear-related midbrain circuits and defensive responses to visual threat.

MKI67 POU4F1 POU4F2

3.96e-061385337983249
Pubmed

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.

SIGLEC14 SIGLEC5

5.90e-06285224799499
Pubmed

Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells.

POU4F1 POU4F2

5.90e-06285227391320
Pubmed

In vitro association of the phosphatidylinositol 3-kinase regulatory subunit (p85) with the human insulin receptor.

PIK3R1 INSR

5.90e-0628528567177
Pubmed

Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.

POU4F1 POU4F2

5.90e-0628528537352
Pubmed

The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancer.

TBX3 TBX2

5.90e-06285223624936
Pubmed

Brn3 transcription factors control terminal osteoclastogenesis.

POU4F1 POU4F2

5.90e-06285217668438
Pubmed

A fluorescent indicator for tyrosine phosphorylation-based insulin signaling pathways.

PIK3R1 INSR

5.90e-06285210500481
Pubmed

Ligand-binding properties of the two isoforms of the human insulin receptor.

PIK3R1 INSR

5.90e-0628528440175
Pubmed

Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor.

POU4F1 POU4F2

5.90e-0628528995448
Pubmed

The alpha-type 85-kDa subunit of phosphatidylinositol 3-kinase is phosphorylated at tyrosines 368, 580, and 607 by the insulin receptor.

PIK3R1 INSR

5.90e-0628528385099
Pubmed

Stratification based on methylation of TBX2 and TBX3 into three molecular grades predicts progression in patients with pTa-bladder cancer.

TBX3 TBX2

5.90e-06285225394776
Pubmed

Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.

POU4F1 POU4F2

5.90e-0628528234287
Pubmed

Complex functional redundancy of Tbx2 and Tbx3 in mouse limb development.

TBX3 TBX2

5.90e-06285235506352
Pubmed

The transcription factors TBX2 and TBX3 interact with human papillomavirus 16 (HPV16) L2 and repress the long control region of HPVs.

TBX3 TBX2

5.90e-06285223388722
Pubmed

Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing.

TBX3 TBX2

5.90e-06285230223900
Pubmed

Insulin-induced activation of phosphatidyl inositol 3-kinase. Demonstration that the p85 subunit binds directly to the COOH terminus of the insulin receptor in intact cells.

PIK3R1 INSR

5.90e-0628527983060
Pubmed

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome.

TBX3 TBX2

5.90e-06285210468588
Pubmed

Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor.

PIK3R1 INSR

5.90e-0628528276809
Pubmed

A single amino acid change converts an inhibitory transcription factor into an activator.

POU4F1 POU4F2

5.90e-0628528662774
Pubmed

Autoregulatory sequences are revealed by complex stability screening of the mouse brn-3.0 locus.

POU4F1 POU4F2

5.90e-06285210414983
Pubmed

Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid.

POU4F1 POU4F2

5.90e-0628527904822
Pubmed

Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.

SIGLEC14 SIGLEC5

5.90e-06285226459514
Pubmed

NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons.

POU4F1 POU4F2

5.90e-0628529582431
Pubmed

Differential expression and subcellular localization of Copines in mouse retina.

POU4F1 POU4F2

5.90e-06285230866042
Pubmed

The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3.

TBX3 TBX2

5.90e-06285225371204
Pubmed

Single nucleotide polymorphisms within functional regions of genes implicated in insulin action and association with the insulin resistant phenotype.

PIK3R1 INSR

5.90e-06285221113646
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

CHD5 CHD4 GATAD2B

6.28e-061585325247294
Pubmed

Integral bHLH factor regulation of cell cycle exit and RGC differentiation.

MKI67 POU4F1 POU4F2

6.28e-061585329770538
Pubmed

The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.

RIF1 EHMT2 CHD4 GATAD2B

7.61e-065185422770845
Pubmed

Human transcription factor protein interaction networks.

FLG FHAD1 RIF1 DST TCF20 EHMT2 RBM33 CHD5 ZKSCAN3 MKI67 HERC2 DDX27 GATAD2B DHX30

9.08e-061429851435140242
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD5 MKI67 CHD4

9.35e-061785327806305
Pubmed

Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice.

MKI67 POU4F1 POU4F2

1.12e-051885317166916
Pubmed

Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina.

MKI67 POU4F1 POU4F2

1.56e-052085316026391
Pubmed

PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis.

PIK3R1 INSR

1.77e-05385211796522
Pubmed

Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression.

POU4F1 POU4F2

1.77e-05385217145718
Pubmed

Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.

SIGLEC14 SIGLEC5

1.77e-05385224698729
Pubmed

T-box family reunion.

TBX3 TBX2

1.77e-0538529196325
Pubmed

Cellular and molecular mechanisms of adipose tissue plasticity in muscle insulin receptor knockout mice.

PIK3R1 INSR

1.77e-05385214684612
Pubmed

Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems.

POU4F1 POU4F2

1.77e-0538529598366
Pubmed

Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.

SIGLEC14 SIGLEC5

1.77e-05385211579105
Pubmed

Insulin-dependent formation of a complex containing an 85-kDa subunit of phosphatidylinositol 3-kinase and tyrosine-phosphorylated insulin receptor substrate 1.

PIK3R1 INSR

1.77e-0538521334490
Pubmed

Cloning and characterization of the mouse Mcoln1 gene reveals an alternatively spliced transcript not seen in humans.

PNPLA6 INSR

1.77e-05385211897010
Pubmed

No association between POU4F1, POU4F2, ISL1 polymorphisms and normal-tension glaucoma.

POU4F1 POU4F2

1.77e-05385232597291
Pubmed

Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.

SIGLEC14 SIGLEC5

1.77e-05385217012248
Pubmed

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family.

TBX3 TBX2

1.77e-0538528988164
Pubmed

Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.

SIGLEC14 SIGLEC5

1.77e-05385231520477
Pubmed

Interaction of the molecular weight 85K regulatory subunit of the phosphatidylinositol 3-kinase with the insulin receptor and the insulin-like growth factor-1 (IGF- I) receptor: comparative study using the yeast two-hybrid system.

PIK3R1 INSR

1.77e-0538528603569
Pubmed

Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.

SIGLEC14 SIGLEC5

1.77e-05385223710953
Pubmed

Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.

SIGLEC14 SIGLEC5

1.77e-05385219783675
Pubmed

Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.

SIGLEC14 SIGLEC5

1.77e-05385230577572
Pubmed

A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.

SIGLEC14 SIGLEC5

1.77e-05385232247614
Pubmed

Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse.

POU4F1 POU4F2

1.77e-05385221935940
Pubmed

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

POU4F1 POU4F2

1.77e-0538528290353
Pubmed

Expression of Drosophila omb-related T-box genes in the developing human and mouse neural retina.

TBX3 TBX2

1.77e-05385211726608
Pubmed

Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors.

POU4F1 POU4F2

1.77e-05385215094508
Pubmed

The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.

POU4F1 POU4F2

1.77e-0538527623109
Pubmed

Systematic identification of intergenic long-noncoding RNAs in mouse retinas using full-length isoform sequencing.

POU4F1 POU4F2

1.77e-05385231286854
Pubmed

Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.

POU4F1 POU4F2

1.77e-05385224736625
Pubmed

The T-Box Transcription Factor TBX2 Regulates Cell Proliferation in the Retinal Pigment Epithelium.

MKI67 TBX2

1.77e-05385228910203
Pubmed

Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development.

POU4F1 POU4F2

1.77e-05385227532212
Pubmed

Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo.

PIK3R1 INSR

1.77e-05385214729945
Pubmed

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.

POU4F1 POU4F2

1.77e-0538527935408
Pubmed

POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.

POU4F1 POU4F2

1.77e-0538529448000
Pubmed

The association of insulin-elicited phosphotyrosine proteins with src homology 2 domains.

PIK3R1 INSR

1.77e-0538521375946
Pubmed

Molecular mechanisms of pituitary organogenesis: In search of novel regulatory genes.

TBX3 TBX2

1.77e-05385220025935
Pubmed

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.

PIK3R1 INSR

1.77e-05385210978177
Pubmed

p68 Sam is a substrate of the insulin receptor and associates with the SH2 domains of p85 PI3K.

PIK3R1 INSR

1.77e-05385210437794
Pubmed

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

TBX3 TBX2

1.77e-05385212000749
Pubmed

Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.

POU4F1 POU4F2

1.77e-0538528162704
Pubmed

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence.

TBX3 TBX2

1.77e-05385211748239
Pubmed

Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.

SIGLEC14 SIGLEC5

1.77e-05385232134149
Pubmed

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis.

FLG DST

1.77e-05385231425296
Pubmed

Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1.

PIK3R1 INSR

1.77e-0538527659087
Pubmed

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.

SIGLEC14 SIGLEC5

1.77e-05385225497369
Pubmed

Siglec-F is a novel intestinal M cell marker.

SIGLEC14 SIGLEC5

1.77e-05385227524237
Pubmed

Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice.

POU4F1 POU4F2

1.77e-05385224608965
Pubmed

Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells.

POU4F1 POU4F2

1.77e-05385219323995
Pubmed

Regulation of otocyst patterning by Tbx2 and Tbx3 is required for inner ear morphogenesis in the mouse.

TBX3 POU4F1 CHD4 TBX2

2.01e-056585433795231
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

TAOK2 CUL5 RIF1 TCF20 MKI67 DDX27 GATAD2B

2.10e-0534185732971831
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

PIKFYVE RIF1 DST TCF20 MKI67 KMT2E

2.38e-0523385637704626
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD8 PRICKLE3 EHMT2 ORC3 INSR MKI67 HERC2 CPS1 ESPL1 GNL1 CHTOP DHX30

2.40e-051155851220360068
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RIF1 TBC1D4 DST PNPLA6 TCF20 EIF2B3 MKI67 PNO1 CHD4 HERC2 DDX27 CHTOP DHX30

2.41e-051353851329467282
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

TCF20 MKI67 PNO1 CHD4 DDX27 GATAD2B DHX30

2.43e-0534985725665578
CytobandEnsembl 112 genes in cytogenetic band chr1q21

FLG TDRKH ADAMTSL4-AS1 CHTOP GATAD2B

9.48e-04404855chr1q21
Cytoband1q21.3

FLG CHTOP GATAD2B

1.37e-031178531q21.3
Cytoband2p14

PNO1 CNRIP1

1.52e-03318522p14
GeneFamilyDoublecortin superfamily

DCDC1 RP1L1

4.63e-04105921369
GeneFamilyPHD finger proteins|NuRD complex

CHD5 CHD4

6.77e-04125921305
GeneFamilyT-boxes

TBX3 TBX2

1.55e-0318592766
GeneFamilyPOU class homeoboxes and pseudogenes

POU4F1 POU4F2

2.53e-0323592523
GeneFamilyPHD finger proteins

CHD5 CHD4 KMT2E

3.17e-039059388
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC14 SIGLEC5

3.75e-0328592745
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

EHMT2 KMT2E

5.49e-0334592487
CoexpressionGSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN

TDRKH ABRAXAS1 INSR MAGI3 CHD4 ANGPTL1

1.82e-05168856M7007
CoexpressionGSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP

PIKFYVE TDRKH RBM33 PRSS12 ABRAXAS1 MAGI3

2.08e-05172856M2951
CoexpressionGAO_LARGE_INTESTINE_ADULT_CH_MKI67HIGH_CELLS

TDRKH MKI67 EXO1 ARHGAP11A ESPL1

2.61e-05107855M39165
CoexpressionBENPORATH_CYCLING_GENES

CFLAR EFHC1 ORC3 CHAF1A MID1 INSR MKI67 EXO1 ARHGAP11A ESPL1

4.70e-056488510M8156
CoexpressionGSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN

CFLAR UGGT1 MKI67 EXO1 ESPL1 DHX30

4.85e-05200856M4587
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

PIKFYVE FLG RIF1 DST PRSS12 KIAA0232 MKI67

5.52e-05300857M8702
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ORC3 CHAF1A MID1 MKI67 EXO1 ARHGAP11A ESPL1

8.92e-081938574b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TDRKH TBC1D4 FAM110D MKI67 ARHGAP11A ESPL1

1.27e-0618085640d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPYC PRSS12 BEND7 TMEM150C ANGPTL1

4.36e-061268559b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPYC CHAF1A MKI67 ARHGAP11A ESPL1

1.52e-051638553f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM110D MKI67 EXO1 ARHGAP11A ESPL1

1.57e-051648554307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM110D MKI67 EXO1 ARHGAP11A ESPL1

1.57e-051648551d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MKI67 EXO1 ARHGAP11A ESPL1 TBX2

1.66e-05166855c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX3 RBM33 CLK3 CHD5 KIF19

1.81e-051698554e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 PRSS12

1.81e-05169855fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

1.81e-0516985514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A MKI67 HEMGN EXO1 ESPL1

1.87e-051708555319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

1.97e-05172855187ae91148d293537afc77e10da2b64302322224
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

1.97e-0517285535c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOL6 MKI67 HEMGN EXO1 ARHGAP11A

1.97e-05172855e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APOL6 MKI67 HEMGN EXO1 ARHGAP11A

2.20e-05176855b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 EXO1 PABPC4L ARHGAP11A ESPL1

2.26e-0517785573ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

2.39e-0517985588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A MKI67 EXO1 MAGI3 ESPL1

2.39e-05179855e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

2.45e-05180855401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

2.45e-05180855f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

CFLAR RIF1 DST APOL6 NFKBIZ

2.66e-051838558f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

TAOK2 PNPLA6 PNO1 MAGI3 KMT2E

2.87e-05186855403ac98f72a42721f84fbd7826f251a88ae534a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

2.95e-051878559351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TDRKH PRSS12 CIAO3 KIAA0232 KIF19

3.02e-05188855c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

FHAD1 CFAP91 EFHC1 PRSS12 KIF19

3.18e-05190855549d813a8f23b175875e53347928941f143e236c
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.18e-05190855426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TBX3 RBM33 MAGI3 KMT2E CDKAL1

3.34e-05192855916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

FHAD1 KRT4 CFAP91 EFHC1 KIF19

3.34e-051928559cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CFLAR TBC1D4 DAPP1 TMEM150C ZC3H7B

3.34e-05192855e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.42e-05193855ea345d34440b25f65358a53dc72831998d1c3620
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

TBX3 RBM33 MAGI3 KMT2E CDKAL1

3.42e-05193855e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-05194855f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-05194855f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell(1)_T_cells_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-051948558f313071933451780309d2174ed27d8cdc734343
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-051948559bbb124001fba7450f4639f47f9b720a483e7242
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-051948556cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-05194855a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-0519485517744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.51e-051948554a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-051948554d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.51e-05194855e14f66f7584909621b776292fbd52808273fd2ee
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-0519585579ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-0519585519829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

MKI67 HEMGN EXO1 ARHGAP11A ESPL1

3.60e-05195855764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.60e-0519585579dc031258579ea328181dda33710dd897f1064a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-05195855926eb3fc5d028be936885bea0654a77db3107234
ToppCell(1)_T_cells-(1)_T_cells_Dividing|(1)_T_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-05195855cf00a0b4f341f0487d5b37810abe2952fdd3f6f2
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.60e-051958553486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.60e-05195855e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellmild-Lymphocytic-Prol._cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-051958559a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.60e-051958551a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.69e-051968551d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.69e-051968551964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.69e-0519685573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBX3 TBC1D4 PRSS12 FAM110D INSR

3.69e-05196855889c9fed857f64664ca1f47fcec9fecb15ed103c
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.69e-05196855d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.69e-051968557b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.78e-0519785584ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellHealthy/Control-T/NK_proliferative|World / Disease group and Cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.78e-051978554a4d3083938783d6f5b87da02f10e501917da0b4
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.78e-05197855e453d085182364ca347cbcc9dc995c62c3353016
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.78e-051978558b616cde333bdbc0c591035ad9e4949155866245
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

3.78e-05197855d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.87e-05198855b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

BEND7 MKI67 EXO1 ARHGAP11A ESPL1

3.87e-0519885550f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCellnormal_Lymph_Node-T/NK_cells-Undetermined|T/NK_cells / Location, Cell class and cell subclass

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.87e-0519885547d572b9db2843aeb2079f33a852babf67270be4
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

FHAD1 EFHC1 PROSER3 INSR KIF19

3.87e-051988556d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

BEND7 MKI67 EXO1 ARHGAP11A ESPL1

3.87e-05198855dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.87e-05198855f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-0519985511c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-0519985536c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-05199855bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Proliferating-Cycling_Progenitors|6_mon / Sample Type, Dataset, Time_group, and Cell type.

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-05199855a99516a5760f49a69b0fe45a9b2316e393252966
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Cycling_T|lymph-node_spleen / Manually curated celltypes from each tissue

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-0519985528fc342d2d178ce33203a78eb9eedae54fa9c916
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-05199855ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-051998554fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-051998557beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellCOVID-19_Mild-T/NK_proliferative|COVID-19_Mild / Disease condition and Cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-051998559f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

DST PIK3R1 INSR APOL6 KMT2E

3.96e-05199855c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-05199855df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCell(1)_T_cells-(1)_T_cell_dividing|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

3.96e-0519985533afdd1b1b951b360ababf440bc556fd9e1c1db2
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 DST MKI67 POU4F2 TBX2

3.96e-051998559940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-052008558f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 PRSS12

4.06e-05200855cc906ff02fd335ff633b3b97afceb670494f910a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells|10w / Sample Type, Dataset, Time_group, and Cell type.

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-05200855a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Mild / Disease, condition lineage and cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-052008556126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCellControl-Control-Lymphocyte-T/NK-T/NK_proliferative|Control / Disease, condition lineage and cell class

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-052008556cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 PRSS12

4.06e-0520085579e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellmedial-Hematologic-Proliferating_NK/T-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-05200855ab1f9f99cb4a381a642a2cfb32e7f8d276c2dda4
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FHAD1 CFAP91 EFHC1 DCDC1 KIF19

4.06e-052008556a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 CFAP91 DCDC1 PRSS12 KIF19

4.06e-05200855926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-05200855e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RBM33 PIK3R1 APOL6 NFKBIZ KMT2E

4.06e-0520085512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-05200855415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCell3'_v3-Lung-Lymphocytic_NK-Cycling_NK|Lung / Manually curated celltypes from each tissue

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-05200855381bafdde6492f020ae93ab8fffa6215c631c570
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-052008552afbb5b5742b956993796621fea7e0c9888754a1
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-0520085504bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FHAD1 CFAP91 DCDC1 PRSS12 KIF19

4.06e-05200855ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FHAD1 CFAP91 EFHC1 DCDC1 PRSS12

4.06e-05200855873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A MKI67 EXO1 ARHGAP11A ESPL1

4.06e-052008554462ebd5d4632788f10a93fadd2babae701c754f
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FHAD1 CFAP91 DCDC1 PRSS12 KIF19

4.06e-0520085506ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
DrugFursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A

TAOK2 CUL5 CFLAR TBC1D4 DAPP1 CTNND2 ARHGAP11A ZC3H7B

7.03e-071988487349_DN
DrugMoricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A

TDRKH RIF1 TBC1D4 MID1 ZKSCAN3 ZC3H7B CDKAL1

8.70e-061988473520_DN
DrugCaffeic acid [3331-39-5]; Up 200; 22.2uM; MCF7; HT_HG-U133A

TDRKH TBC1D4 PIK3R1 INSR DAPP1 CPS1 CHTOP

8.70e-061988475352_UP
Drugaminophosphonous acid

MID1 INSR

1.35e-052842CID006327677
DiseaseMalignant neoplasm of breast

CUL5 TBX3 RIF1 ABCB10 PRICKLE3 ABRAXAS1 CHD5 BEND7 MKI67 EXO1 HERC2 ARHGAP11A

5.14e-0510748412C0006142
Diseasepropionylglycine measurement

TPD52L3 CPS1

7.96e-055842EFO_0800207
DiseaseX-16570 measurement

TPD52L3 CPS1

1.19e-046842EFO_0800759
Diseasegamma-glutamylglycine measurement

TPD52L3 CPS1

1.67e-047842EFO_0800670
Diseaseosteoarthritis, knee, body mass index

TAOK2 CPS1 CDKAL1

2.19e-0441843EFO_0004340, EFO_0004616
Diseasegestational diabetes (is_implicated_in)

INSR CDKAL1

2.22e-048842DOID:11714 (is_implicated_in)
Diseasehair colour measurement, eye colour measurement, skin pigmentation measurement

RAB11FIP2 HERC2

3.55e-0410842EFO_0007009, EFO_0007822, EFO_0009764
Diseasedolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement

SIGLEC14 SIGLEC5

3.55e-0410842EFO_0801544
Diseasesialic acid-binding Ig-like lectin 14 measurement

SIGLEC14 SIGLEC5

5.19e-0412842EFO_0008284
Diseaseclostridium difficile infection

OR10A7 EHMT2 INSR CTNND2

7.76e-04144844EFO_0009130
Diseasered blood cell density measurement

TBC1D4 TPD52L3 DST DCDC1 PIK3R1 RAB11FIP2 CHD4 CPS1 CDKAL1

8.94e-04880849EFO_0007978
DiseaseColorectal Neoplasms

ABCB10 CHD5 ZKSCAN3 MKI67 EXO1

1.19e-03277845C0009404
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

EXO1 NFKBIZ

1.33e-0319842C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

EXO1 NFKBIZ

1.33e-0319842C2936783
Diseaseplatelet component distribution width

KIAA0232 EIF2B3 DAPP1 HEMGN SIGLEC14 CNRIP1 SIGLEC5 CPS1

1.40e-03755848EFO_0007984
DiseaseCorneal astigmatism

PIK3R1 HERC2 CTNND2

1.40e-0377843EFO_1002040
Diseasecitrulline measurement

RP1L1 CPS1

1.47e-0320842EFO_0009777
Diseasehepatocellular carcinoma (is_marker_for)

TBX3 CHD5 INSR CHD4 CPS1

1.71e-03301845DOID:684 (is_marker_for)
Diseaselung adenocarcinoma (is_marker_for)

EHMT2 PIK3R1 MKI67

1.86e-0385843DOID:3910 (is_marker_for)
Diseasebasal cell carcinoma

PIK3R1 RAB11FIP2 EXO1 HERC2

2.11e-03189844EFO_0004193
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

EXO1 NFKBIZ

2.49e-0326842C0009405
Diseaseatopic asthma

FLG TDRKH TPD52L3 EHMT2

2.54e-03199844EFO_0010638
Diseasesunburn

FLG RAB11FIP2 HERC2

2.63e-0396843EFO_0003958
DiseaseHereditary non-polyposis colorectal cancer syndrome

EXO1 NFKBIZ

2.68e-0327842C1112155

Protein segments in the cluster

PeptideGeneStartEntry
KRRGAQIQAAREKNI

ABRAXAS1

256

Q6UWZ7
GRSQLRGLQEKLKQL

CCDC115

161

Q96NT0
QKRGKINLIGRLQLT

CUL5

681

Q93034
QQEDLARNLGKGKRI

CHD5

1331

Q8TDI0
ARNLGKGKRIRKQVN

CHD5

1336

Q8TDI0
RQKGRQKAGLEKGNR

ADAMTSL4-AS1

56

Q5T5F5
SLQQKVRSRARGVGK

APOL6

291

Q9BWW8
RGKSQVALKIIRNVG

CLK3

326

P49761
GGQKQRIAIARALLK

ABCB10

636

Q9NRK6
LQLNRKLRLGVGNRA

EHMT2

901

Q96KQ7
CRGGQFKIKKINQRR

ANGPTL1

21

O95841
RQRSQIKGKDSEGRR

CFAP92

336

Q9ULG3
SSLERRNNRKGNKGR

FLG

126

P20930
RLQRDQERLGKQLKL

CHAF1A

336

Q13111
NLIQVRQGKVTRQGK

DHX30

1026

Q7L2E3
GRSKEQRLKEQLGAQ

CFLAR

206

O15519
DNKIKAEIRRQGGIQ

CTNND2

581

Q9UQB3
VLGRRQKALGKNRSA

DDX27

66

Q96GQ7
GKRKNIEGKLERRNI

CFAP91

346

Q7Z4T9
KRNQNREGLRALQKD

PDRG1

36

Q9NUG6
RRQQQAGARKKELLE

RBM33

811

Q96EV2
LQAQDIRGRKKGRGV

RGPD8

946

O14715
KQRRIKLGVTQADVG

POU4F1

276

Q01851
NGRLRSVIQRGSGKK

PNPLA6

671

Q8IY17
VRLRVLQNGEKNKNR

DCDC1

936

M0R2J8
RRQKRIIGGKNSLRG

PRSS12

626

P56730
GLRNNEVKGAVKRTI

OR10A7

291

Q8NGE5
QIRRILKGKSIQQRA

NFKBIZ

701

Q9BYH8
KNLLKVENGVTRRGR

MAGI3

1206

Q5TCQ9
NRIQVKRSRSKGGLA

HERC2

4421

O95714
QRKQQLDGALRQAKG

DST

6476

Q03001
RKQLDTLGNDKGRLQ

KRT4

196

P19013
IDISNNRLGRKGIKQ

EPYC

216

Q99645
EIRNKKGRNGQSRLS

KIAA0232

321

Q92628
QRIALRLGNGNDKKE

KMT2E

301

Q8IZD2
LQDKRERKRGLQDGL

GNL1

16

P36915
KLRQKLQRNAAGRLE

LRRC8E

406

Q6NSJ5
KGRQERNDIALKTNG

INSR

476

P06213
KRGQKATLLQQRREG

MKI67

906

P46013
GKGIEERQQLIKQLR

GATAD2B

156

Q8WXI9
RKGGRRAKKRQAEQL

PNO1

21

Q9NRX1
LRNKEVKGALGRVIR

OR12D2

291

P58182
RNKAENLLRGKRDGT

PIK3R1

631

P27986
GNRRGRKRQQNTELK

HEMGN

71

Q9BXL5
QRLKRKIDEQTGRGQ

KIF19

376

Q2TAC6
SQQRKRENLGRGIVR

PRICKLE3

161

O43900
RRKKQLLRDLSGLQG

PIKFYVE

1101

Q9Y2I7
NRLQDLFQQEKGRKR

PIKFYVE

1506

Q9Y2I7
IGSGQRIEAKAKRVN

EIF2B3

426

Q9NR50
GIKNNVIRLLVKRGA

CPS1

226

P31327
QGQKRSGRGRQKLAS

ESPL1

1311

Q14674
QLKNQLGRKEELLRG

FHAD1

1296

B1AJZ9
INRAIRQQKVGTRKA

FHAD1

1366

B1AJZ9
VRLLGQKKDNGRRLG

CDKAL1

176

Q5VV42
KVDGQRFGQNRTIKL

CNRIP1

26

Q96F85
IRKQLNQGEGTIRSR

DAPP1

261

Q9UN19
SGILQGKLIKRQRLA

EFHC1

141

Q5JVL4
GKLIKRQRLAKNDRG

EFHC1

146

Q5JVL4
NGKRKRGLNDNRKGL

BEND7

331

Q8N7W2
QEDLARNLGKGKRIR

CHD4

1326

Q14839
QLKRERIRGCQGVKL

PABPC4L

281

P0CB38
KNSRDLGGQIKLREI

ORC3

86

Q9UBD5
VRRSLRLKFNLGKNG

ARHGAP11A

431

Q6P4F7
TGNGRREKRKQLTLQ

TBX3

306

O15119
RGLGQLIRAKNIKTI

RIF1

2316

Q5UIP0
KRQNARKIQIGSKGR

MTRF1L

306

Q9UGC7
KQRRIKLGVTQADVG

POU4F2

266

Q12837
GRLQLRTLKQGDKEI

RNF128

256

Q8TEB7
TQGRFRLLGDVQKKN

SIGLEC5

86

O15389
VRQQPKSLKVRAGQR

TAOK2

736

Q9UL54
RQRRKLEQAQGSKGD

PROSER3

291

Q2NL68
TLKVNIKNEGRRVGI

TMEM150C

151

B9EJG8
SVNKENAKGQGLVRR

FAM110D

96

Q8TAY7
RQANLLKGKQLLREG

EXO1

96

Q9UQ84
QINQDGGTRRLEKAK

CIAO3

51

Q9H6Q4
KQRLGKSNIQARLGR

CHTOP

76

Q9Y3Y2
LIIGRQGANIKQLRK

TDRKH

66

Q9Y2W6
STKRELQKLQGRAGR

RP1L1

1571

Q8IWN7
RDTGNGRREKRKQLT

TBX2

286

Q13207
SQRGLDGLKRNVTLQ

MID1

66

O15344
GTEQNRVRNKLKRLI

ARHGAP9

506

Q9BRR9
RLESKQGKRIKNRGE

RAB11FIP2

121

Q7L804
EQTKLVRGRKGQRSL

TCF20

1656

Q9UGU0
KRKLNLQDGRAQGVR

TBC1D4

651

O60343
LQRKQKNATGGRRHI

ZKSCAN3

301

Q9BRR0
KRKLGLTALVGLRQN

TPD52L3

61

Q96J77
TQGRFRLLGDVQKKN

SIGLEC14

86

Q08ET2
LKKGQRAVISNGRII

UGGT1

886

Q9NYU2
GQELAQKLGLRVRKA

ZC3H7B

156

Q9UGR2