Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic cation channel activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	2.53e-08	343	41	9	GO:0005261
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN4A TRPM2 SCN8A SCN9A	6.86e-08	52	41	5	GO:0005272
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN4A SCN8A SCN9A	2.21e-07	26	41	4	GO:0005248
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	3.02e-07	459	41	9	GO:0005216
GeneOntologyMolecularFunction	channel activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	9.28e-07	525	41	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	9.43e-07	526	41	9	GO:0022803
GeneOntologyMolecularFunction	G protein-coupled purinergic nucleotide receptor activity	P2RY13 P2RY12 P2RY2	2.27e-06	13	41	3	GO:0045028
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN8A SCN9A	2.88e-06	14	41	3	GO:0031402
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TRPA1 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	3.96e-06	465	41	8	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	6.36e-06	664	41	9	GO:0008324
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	TRPA1 RYR2 TRPM2	6.42e-06	18	41	3	GO:0015278
GeneOntologyMolecularFunction	nucleotide receptor activity	P2RY13 P2RY12 P2RY2	1.20e-05	22	41	3	GO:0016502
GeneOntologyMolecularFunction	purinergic nucleotide receptor activity	P2RY13 P2RY12 P2RY2	1.20e-05	22	41	3	GO:0001614
GeneOntologyMolecularFunction	transmembrane transporter activity	CYB561D1 TRPA1 KCNQ4 ABCA8 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	1.79e-05	1180	41	11	GO:0022857
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN8A SCN9A	2.02e-05	26	41	3	GO:0031420
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SCN1A SCN4A TRPM2 SCN8A SCN9A	2.54e-05	171	41	5	GO:0015081
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	2.62e-05	793	41	9	GO:0015075
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPA1 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	3.45e-05	627	41	8	GO:0022890
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	TRPA1 RYR2 TRPM2	3.47e-05	31	41	3	GO:0099604
GeneOntologyMolecularFunction	transporter activity	CYB561D1 TRPA1 KCNQ4 ABCA8 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	4.06e-05	1289	41	11	GO:0005215
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM3B KDM3A	4.10e-05	5	41	2	GO:0140683
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	TRPA1 RYR2 TRPM2	4.20e-05	33	41	3	GO:0005217
GeneOntologyMolecularFunction	gated channel activity	TRPA1 KCNQ4 SCN1A PIEZO1 RYR2 TRPM2	5.75e-05	334	41	6	GO:0022836
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPA1 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	1.31e-04	758	41	8	GO:0015318
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM3B KDM3A	3.69e-04	14	41	2	GO:0032454
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH5 DNAH17	6.16e-04	18	41	2	GO:0008569
GeneOntologyMolecularFunction	scavenger receptor activity	ACKR2 DMBT1	1.40e-03	27	41	2	GO:0005044
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR10G6 P2RY13 ACKR2 GPR20 TRPA1 PTGDR IL17RD P2RY12 P2RY2	1.42e-03	1353	41	9	GO:0004888
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM3B KDM3A	1.50e-03	28	41	2	GO:0141052
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH5 DNAH17	1.50e-03	28	41	2	GO:0051959
GeneOntologyMolecularFunction	histone demethylase activity	KDM3B KDM3A	1.84e-03	31	41	2	GO:0032452
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR10G6 P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	1.96e-03	884	41	7	GO:0004930
GeneOntologyMolecularFunction	protein demethylase activity	KDM3B KDM3A	1.96e-03	32	41	2	GO:0140457
GeneOntologyMolecularFunction	snoRNA binding	NOP56 TSR1	2.21e-03	34	41	2	GO:0030515
GeneOntologyMolecularFunction	pattern recognition receptor activity	NOD1 DMBT1	2.34e-03	35	41	2	GO:0038187
GeneOntologyMolecularFunction	calcium channel activity	TRPA1 RYR2 TRPM2	2.35e-03	129	41	3	GO:0005262
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH5 DNAH17	2.62e-03	37	41	2	GO:0045505
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TRPA1 RYR2 TRPM2	2.96e-03	140	41	3	GO:0099094
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	TRPA1 RYR2 TRPM2	3.66e-03	151	41	3	GO:0015085
GeneOntologyMolecularFunction	demethylase activity	KDM3B KDM3A	3.68e-03	44	41	2	GO:0032451
GeneOntologyMolecularFunction	heme binding	CYB561D1 DUOX1 GUCY1A2	3.87e-03	154	41	3	GO:0020037
GeneOntologyMolecularFunction	tetrapyrrole binding	CYB561D1 DUOX1 GUCY1A2	4.61e-03	164	41	3	GO:0046906
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	TRPA1 KCNQ4 SCN1A	6.16e-03	182	41	3	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	TRPA1 KCNQ4 SCN1A	6.35e-03	184	41	3	GO:0022832
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	TRPA1 RYR2 TRPM2	7.24e-03	193	41	3	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	TRPA1 RYR2 TRPM2	7.65e-03	197	41	3	GO:0022834
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM3B KDM3A	7.88e-03	65	41	2	GO:0016706
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH5 ABCA8 CECR2 SMC1B DNAH17	8.12e-03	614	41	5	GO:0140657
GeneOntologyMolecularFunction	microtubule motor activity	DNAH5 DNAH17	9.09e-03	70	41	2	GO:0003777
GeneOntologyMolecularFunction	cargo receptor activity	ACKR2 DMBT1	1.32e-02	85	41	2	GO:0038024
GeneOntologyMolecularFunction	cytokine receptor activity	ACKR2 IL17RD	1.69e-02	97	41	2	GO:0004896
GeneOntologyMolecularFunction	antioxidant activity	KDM3B DUOX1	1.69e-02	97	41	2	GO:0016209
GeneOntologyMolecularFunction	dioxygenase activity	KDM3B KDM3A	1.73e-02	98	41	2	GO:0051213
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	1.44e-07	62	41	5	GO:0086002
GeneOntologyBiologicalProcess	neuronal action potential	TRPA1 SCN1A SCN4A SCN8A SCN9A	1.56e-07	63	41	5	GO:0019228
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN4A SCN8A SCN9A	7.56e-07	36	41	4	GO:0086010
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN1A RYR2 SCN4A SCN8A SCN9A	7.90e-07	87	41	5	GO:0086001
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	1.10e-06	93	41	5	GO:0086003
GeneOntologyBiologicalProcess	G protein-coupled purinergic nucleotide receptor signaling pathway	P2RY13 P2RY12 P2RY2	2.06e-06	13	41	3	GO:0035589
GeneOntologyBiologicalProcess	action potential	TRPA1 SCN1A RYR2 SCN4A SCN8A SCN9A	2.69e-06	201	41	6	GO:0001508
GeneOntologyBiologicalProcess	transmission of nerve impulse	TRPA1 SCN1A SCN4A SCN8A SCN9A	2.77e-06	112	41	5	GO:0019226
GeneOntologyBiologicalProcess	actin-mediated cell contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	5.13e-06	127	41	5	GO:0070252
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	TRPA1 P2RY12 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	1.16e-05	942	41	10	GO:0098655
GeneOntologyBiologicalProcess	actin filament-based movement	SCN1A RYR2 SCN4A SCN8A SCN9A	1.27e-05	153	41	5	GO:0030048
GeneOntologyBiologicalProcess	detection of mechanical stimulus	TRPA1 SCN1A PIEZO1 SCN9A	1.47e-05	75	41	4	GO:0050982
GeneOntologyBiologicalProcess	response to purine-containing compound	DUOX1 P2RY12 P2RY2 RYR2 TRPM2	1.88e-05	166	41	5	GO:0014074
GeneOntologyBiologicalProcess	cardiac muscle contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	1.94e-05	167	41	5	GO:0060048
GeneOntologyBiologicalProcess	blood circulation	HSD11B2 TRPA1 P2RY2 SCN1A RYR2 SCN4A SCN8A SCN9A	3.47e-05	648	41	8	GO:0008015
GeneOntologyBiologicalProcess	purinergic nucleotide receptor signaling pathway	P2RY13 P2RY12 P2RY2	3.82e-05	33	41	3	GO:0035590
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	TRPA1 P2RY12 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	4.94e-05	1115	41	10	GO:0034220
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SCN1A SCN4A TRPM2 SCN8A SCN9A	5.54e-05	208	41	5	GO:0035725
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	TRPA1 P2RY12 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	6.60e-05	922	41	9	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transport	TRPA1 P2RY12 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	6.74e-05	1157	41	10	GO:0006812
GeneOntologyBiologicalProcess	striated muscle contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	6.78e-05	217	41	5	GO:0006941
GeneOntologyBiologicalProcess	circulatory system process	HSD11B2 TRPA1 P2RY2 SCN1A RYR2 SCN4A SCN8A SCN9A	8.27e-05	733	41	8	GO:0003013
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception of pain	TRPA1 SCN1A SCN9A	8.51e-05	43	41	3	GO:0062149
GeneOntologyBiologicalProcess	membrane depolarization	SCN1A SCN4A SCN8A SCN9A	9.65e-05	121	41	4	GO:0051899
GeneOntologyBiologicalProcess	regulation of membrane potential	TRPA1 SCN1A PIEZO1 RYR2 SCN4A SCN8A SCN9A	1.04e-04	559	41	7	GO:0042391
GeneOntologyBiologicalProcess	sensory perception of mechanical stimulus	TRPA1 KCNQ4 SCN1A SCN8A SCN9A	1.05e-04	238	41	5	GO:0050954
GeneOntologyBiologicalProcess	metal ion transport	TRPA1 P2RY12 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	1.23e-04	1000	41	9	GO:0030001
GeneOntologyBiologicalProcess	response to mechanical stimulus	TRPA1 SCN1A PIEZO1 RYR2 SCN9A	1.25e-04	247	41	5	GO:0009612
GeneOntologyBiologicalProcess	muscle contraction	TRPA1 SCN1A RYR2 SCN4A SCN8A SCN9A	1.30e-04	400	41	6	GO:0006936
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	TRPA1 P2RY12 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	1.40e-04	1017	41	9	GO:0098660
GeneOntologyBiologicalProcess	response to organic cyclic compound	P2RY13 KDM3A DUOX1 HSD11B2 TRPA1 P2RY12 P2RY2 RYR2 TRPM2	1.75e-04	1048	41	9	GO:0014070
GeneOntologyBiologicalProcess	calcium-mediated signaling	ACKR2 TRPA1 P2RY12 RYR2 TRPM2	1.76e-04	266	41	5	GO:0019722
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	TRPA1 SCN1A SCN9A	1.98e-04	57	41	3	GO:0050974
GeneOntologyBiologicalProcess	sodium ion transport	SCN1A SCN4A TRPM2 SCN8A SCN9A	2.06e-04	275	41	5	GO:0006814
GeneOntologyBiologicalProcess	manganese ion transmembrane transport	RYR2 TRPM2	2.51e-04	12	41	2	GO:0071421
GeneOntologyBiologicalProcess	monoatomic ion transport	TRPA1 P2RY12 KCNQ4 SCN1A PIEZO1 RYR2 SCN4A TRPM2 SCN8A SCN9A	2.78e-04	1374	41	10	GO:0006811
GeneOntologyBiologicalProcess	heart contraction	SCN1A RYR2 SCN4A SCN8A SCN9A	2.98e-04	298	41	5	GO:0060047
GeneOntologyBiologicalProcess	manganese ion transport	RYR2 TRPM2	3.46e-04	14	41	2	GO:0006828
GeneOntologyBiologicalProcess	cellular response to purine-containing compound	RYR2 TRPM2	3.46e-04	14	41	2	GO:0071415
GeneOntologyBiologicalProcess	positive regulation of integrin activation	P2RY12 PIEZO1	3.46e-04	14	41	2	GO:0033625
GeneOntologyBiologicalProcess	heart process	SCN1A RYR2 SCN4A SCN8A SCN9A	3.52e-04	309	41	5	GO:0003015
GeneOntologyBiologicalProcess	detection of external stimulus	TRPA1 SCN1A PIEZO1 SCN9A	3.80e-04	173	41	4	GO:0009581
GeneOntologyBiologicalProcess	detection of abiotic stimulus	TRPA1 SCN1A PIEZO1 SCN9A	3.97e-04	175	41	4	GO:0009582
GeneOntologyBiologicalProcess	detection of stimulus	OR10G6 NOD1 TRPA1 SCN1A PIEZO1 RYR2 SCN9A	4.98e-04	722	41	7	GO:0051606
GeneOntologyBiologicalProcess	regulation of action potential	TRPA1 RYR2 SCN9A	5.59e-04	81	41	3	GO:0098900
GeneOntologyBiologicalProcess	muscle system process	TRPA1 SCN1A RYR2 SCN4A SCN8A SCN9A	6.91e-04	547	41	6	GO:0003012
GeneOntologyBiologicalProcess	regulation of integrin activation	P2RY12 PIEZO1	7.16e-04	20	41	2	GO:0033623
GeneOntologyBiologicalProcess	cellular response to ATP	P2RY12 P2RY2	7.90e-04	21	41	2	GO:0071318
GeneOntologyBiologicalProcess	positive regulation of cell adhesion mediated by integrin	P2RY12 PIEZO1	9.50e-04	23	41	2	GO:0033630
GeneOntologyBiologicalProcess	positive regulation of cytosolic calcium ion concentration	ACKR2 PTGDR P2RY2 RYR2	1.00e-03	224	41	4	GO:0007204
GeneOntologyBiologicalProcess	outer dynein arm assembly	DNAH5 DNAH17	1.03e-03	24	41	2	GO:0036158
GeneOntologyBiologicalProcess	cellular response to organic cyclic compound	P2RY13 KDM3A P2RY12 P2RY2 RYR2 TRPM2	1.17e-03	605	41	6	GO:0071407
GeneOntologyBiologicalProcess	response to abiotic stimulus	HSD11B2 TRPA1 GUCY1A2 BABAM2 SCN1A PIEZO1 RYR2 TRPM2 SCN9A	1.18e-03	1361	41	9	GO:0009628
GeneOntologyBiologicalProcess	sensory perception of pain	TRPA1 SCN1A SCN9A	1.19e-03	105	41	3	GO:0019233
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of pain	TRPA1 SCN1A	1.22e-03	26	41	2	GO:0050966
GeneOntologyBiologicalProcess	integrin activation	P2RY12 PIEZO1	1.51e-03	29	41	2	GO:0033622
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled receptor signaling pathway	GPR20 P2RY12 P2RY2	2.34e-03	133	41	3	GO:0007200
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN4A SCN8A SCN9A	2.97e-08	17	41	4	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN4A SCN8A SCN9A	2.92e-07	29	41	4	GO:0034706
GeneOntologyCellularComponent	cation channel complex	KCNQ4 SCN1A RYR2 SCN4A SCN8A SCN9A	6.13e-06	235	41	6	GO:0034703
GeneOntologyCellularComponent	monoatomic ion channel complex	KCNQ4 SCN1A RYR2 SCN4A SCN8A SCN9A	8.85e-05	378	41	6	GO:0034702
GeneOntologyCellularComponent	outer dynein arm	DNAH5 DNAH17	2.45e-04	12	41	2	GO:0036157
GeneOntologyCellularComponent	transmembrane transporter complex	KCNQ4 SCN1A RYR2 SCN4A SCN8A SCN9A	5.09e-04	523	41	6	GO:1902495
GeneOntologyCellularComponent	basal plasma membrane	NOD1 P2RY12 P2RY2 KCNQ4 ABCA8	6.15e-04	354	41	5	GO:0009925
GeneOntologyCellularComponent	transporter complex	KCNQ4 SCN1A RYR2 SCN4A SCN8A SCN9A	6.63e-04	550	41	6	GO:1990351
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN8A	6.97e-04	20	41	2	GO:0033268
GeneOntologyCellularComponent	basal part of cell	NOD1 P2RY12 P2RY2 KCNQ4 ABCA8	8.26e-04	378	41	5	GO:0045178
GeneOntologyCellularComponent	axonemal dynein complex	DNAH5 DNAH17	1.09e-03	25	41	2	GO:0005858
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN8A	1.47e-03	29	41	2	GO:0043194
GeneOntologyCellularComponent	Z disc	SCN1A RYR2 SCN8A	3.22e-03	151	41	3	GO:0030018
HumanPheno	Complex febrile seizure	SCN1A SCN8A SCN9A	2.02e-05	16	18	3	HP:0011172
MousePheno	decreased paired-pulse ratio	SCN1A RYR2	3.23e-05	4	33	2	MP:0014253
MousePheno	abnormal paired-pulse ratio	SCN1A RYR2	1.13e-04	7	33	2	MP:0014252
MousePheno	ventricular fibrillation	SCN1A RYR2	1.13e-04	7	33	2	MP:0006110
Domain	Ion_trans_dom	TRPA1 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	9.82e-11	114	40	8	IPR005821
Domain	Ion_trans	TRPA1 KCNQ4 SCN1A RYR2 SCN4A TRPM2 SCN8A SCN9A	9.82e-11	114	40	8	PF00520
Domain	Na_channel_asu	SCN1A SCN4A SCN8A SCN9A	3.75e-09	10	40	4	IPR001696
Domain	Na_trans_assoc	SCN1A SCN4A SCN8A SCN9A	3.75e-09	10	40	4	IPR010526
Domain	Na_trans_assoc	SCN1A SCN4A SCN8A SCN9A	3.75e-09	10	40	4	PF06512
Domain	Na_trans_cytopl	SCN1A SCN8A SCN9A	1.81e-07	6	40	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN8A SCN9A	1.81e-07	6	40	3	IPR024583
Domain	Channel_four-helix_dom	SCN1A SCN4A SCN8A SCN9A	6.56e-06	57	40	4	IPR027359
Domain	-	SCN1A SCN4A SCN8A SCN9A	6.56e-06	57	40	4	1.20.120.350
Domain	IQ	SCN1A SCN4A SCN8A SCN9A	1.58e-05	71	40	4	PF00612
Domain	IQ	SCN1A SCN4A SCN8A SCN9A	2.66e-05	81	40	4	SM00015
Domain	IQ_motif_EF-hand-BS	SCN1A SCN4A SCN8A SCN9A	4.04e-05	90	40	4	IPR000048
Domain	IQ	SCN1A SCN4A SCN8A SCN9A	4.59e-05	93	40	4	PS50096
Domain	EF-hand-dom_pair	DUOX1 SCN1A RYR2 SCN8A SCN9A	3.51e-04	287	40	5	IPR011992
Domain	7tm_1	OR10G6 P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	5.24e-04	677	40	7	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR10G6 P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	5.62e-04	685	40	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR10G6 P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	5.91e-04	691	40	7	PS50262
Domain	GPCR_Rhodpsn	OR10G6 P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	5.97e-04	692	40	7	IPR000276
Domain	JmjC	KDM3B KDM3A	1.20e-03	24	40	2	PF02373
Domain	JMJC	KDM3B KDM3A	2.13e-03	32	40	2	PS51184
Domain	JmjC_dom	KDM3B KDM3A	2.13e-03	32	40	2	IPR003347
Domain	JmjC	KDM3B KDM3A	2.26e-03	33	40	2	SM00558
Domain	GPCR_Rhodpsn_7TM	P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	2.83e-03	670	40	6	IPR017452
Domain	ABC_transporter-like	ABCA8 SMC1B	5.13e-03	50	40	2	IPR003439
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN4A SCN8A SCN9A	1.34e-06	31	38	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN4A SCN8A SCN9A	1.53e-06	32	38	4	M27455
Pathway	REACTOME_P2Y_RECEPTORS	P2RY13 P2RY12 P2RY2	2.94e-06	11	38	3	MM15049
Pathway	REACTOME_P2Y_RECEPTORS	P2RY13 P2RY12 P2RY2	3.91e-06	12	38	3	M10960
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	P2RY13 P2RY12 P2RY2	9.88e-06	16	38	3	M6786
Pathway	REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS	P2RY13 P2RY12 P2RY2	9.88e-06	16	38	3	MM15050
Pathway	REACTOME_MUSCLE_CONTRACTION	GUCY1A2 SCN1A RYR2 SCN4A SCN8A SCN9A	1.56e-05	203	38	6	M5485
Pathway	REACTOME_CARDIAC_CONDUCTION	SCN1A RYR2 SCN4A SCN8A SCN9A	2.43e-05	130	38	5	M27454
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	P2RY13 ACKR2 GPR20 PTGDR P2RY12 P2RY2	6.25e-05	260	38	6	M39397
Pathway	WP_PURINERGIC_SIGNALING	P2RY13 P2RY12 P2RY2	9.32e-05	33	38	3	M39855
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	P2RY13 ACKR2 PTGDR P2RY12 P2RY2	1.34e-04	186	38	5	MM15994
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	TRPA1 SCN8A SCN9A	2.53e-04	46	38	3	M46450
Pathway	WP_RETT_SYNDROME	CECR2 SCN1A SCN8A	2.87e-04	48	38	3	M39759
Pathway	REACTOME_L1CAM_INTERACTIONS	SCN1A SCN4A SCN8A SCN9A	3.04e-04	121	38	4	M872
Pathway	WP_GPCRS_NONODORANT	P2RY13 ACKR2 PTGDR P2RY12 P2RY2	6.95e-04	266	38	5	MM15843
Pathway	BIOCARTA_RACC_PATHWAY	GUCY1A2 KCNQ4	7.27e-04	15	38	2	M22002
Pathway	REACTOME_SURFACTANT_METABOLISM	DMBT1 P2RY2	1.73e-03	23	38	2	MM15279
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	P2RY13 ACKR2 PTGDR P2RY12 P2RY2	1.82e-03	330	38	5	M18334
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	P2RY13 ACKR2 PTGDR P2RY12 P2RY2	1.89e-03	333	38	5	MM14963
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPA1 RYR2 TRPM2	2.37e-03	99	38	3	MM14910
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH5 DNAH17	2.38e-03	27	38	2	M47755
Pathway	REACTOME_TRP_CHANNELS	TRPA1 TRPM2	2.56e-03	28	38	2	MM14943
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN8A	2.56e-03	28	38	2	M45519
Pathway	REACTOME_TRP_CHANNELS	TRPA1 TRPM2	2.56e-03	28	38	2	M27241
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM3B KDM3A	2.74e-03	29	38	2	MM14934
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPA1 RYR2 TRPM2	2.88e-03	106	38	3	M27200
Pathway	REACTOME_SURFACTANT_METABOLISM	DMBT1 P2RY2	2.93e-03	30	38	2	M27566
Pathway	WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION	HSD11B2 PTGDR	3.33e-03	32	38	2	MM15850
Pathway	KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY	KDM3B KDM3A	3.98e-03	35	38	2	M47969
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN4A SCN8A SCN9A	2.54e-10	9	43	4	16382098
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNQ4 SCN1A RYR2 SCN4A SCN8A SCN9A	1.97e-08	139	43	6	16985003
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN8A SCN9A	3.51e-08	6	43	3	23652591
Pubmed	Expression of P2Y(6) receptors in the developing mouse skeletal muscle and after injury and repair.	P2RY13 P2RY12 P2RY2	6.14e-08	7	43	3	21413988
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN4A SCN8A	1.47e-07	9	43	3	15746173
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN8A SCN9A	4.99e-07	13	43	3	15123669
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	1.49e-06	2	43	2	37901435
Pubmed	State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.	SCN4A SCN9A	1.49e-06	2	43	2	18079277
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	1.49e-06	2	43	2	26410685
Pubmed	Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia.	P2RY13 P2RY12	1.49e-06	2	43	2	28800362
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	1.49e-06	2	43	2	33411788
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	1.49e-06	2	43	2	31943325
Pubmed	Role of the P2Y12 receptor in the modulation of murine dendritic cell function by ADP.	P2RY13 P2RY12	1.49e-06	2	43	2	20952684
Pubmed	Sodium channel slow inactivation interferes with open channel block.	SCN8A SCN9A	1.49e-06	2	43	2	27174182
Pubmed	The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors.	P2RY12 P2RY2	1.49e-06	2	43	2	14645014
Pubmed	Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.	SCN1A SCN8A	1.49e-06	2	43	2	37665666
Pubmed	The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.	SCN1A SCN8A	1.49e-06	2	43	2	17881658
Pubmed	Presynaptic inhibition of spontaneous acetylcholine release mediated by P2Y receptors at the mouse neuromuscular junction.	P2RY13 P2RY12	1.49e-06	2	43	2	16843602
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN9A	4.48e-06	3	43	2	33895391
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN8A	4.48e-06	3	43	2	32845893
Pubmed	Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior.	P2RY13 P2RY12	4.48e-06	3	43	2	20398327
Pubmed	Autocrine purinergic receptor signaling is essential for macrophage chemotaxis.	P2RY12 P2RY2	4.48e-06	3	43	2	20664064
Pubmed	Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.	SCN4A SCN9A	4.48e-06	3	43	2	20038812
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN8A	4.48e-06	3	43	2	28518218
Pubmed	Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.	SCN1A SCN8A	4.48e-06	3	43	2	24704313
Pubmed	Migration and Phagocytic Ability of Activated Microglia During Post-natal Development is Mediated by Calcium-Dependent Purinergic Signalling.	P2RY12 P2RY2	4.48e-06	3	43	2	25575683
Pubmed	Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice.	GPR20 P2RY2	4.48e-06	3	43	2	12644577
Pubmed	The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.	SCN1A SCN8A	4.48e-06	3	43	2	28117367
Pubmed	The role of Nav1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes.	TRPA1 SCN9A	4.48e-06	3	43	2	31285762
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN8A	4.48e-06	3	43	2	17928448
Pubmed	Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.	SCN1A SCN8A	4.48e-06	3	43	2	26182346
Pubmed	De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.	SCN1A SCN8A	4.48e-06	3	43	2	31054517
Pubmed	Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.	SCN8A SCN9A	4.48e-06	3	43	2	15302875
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN8A	8.94e-06	4	43	2	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN8A	8.94e-06	4	43	2	35031483
Pubmed	Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis.	KDM3B KDM3A	8.94e-06	4	43	2	29526734
Pubmed	Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.	KDM3B KDM3A	8.94e-06	4	43	2	23593242
Pubmed	Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent.	P2RY12 P2RY2	8.94e-06	4	43	2	22057273
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN8A	8.94e-06	4	43	2	29578003
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN8A	8.94e-06	4	43	2	21156207
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	SCN1A SCN9A	8.94e-06	4	43	2	22260870
Pubmed	Teasing out the role of ATP in immune responses. See referenced article, J. Biol. Chem. 2011, 286, 44776–44787. Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent.	P2RY12 P2RY2	8.94e-06	4	43	2	22199395
Pubmed	JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.	KDM3B KDM3A	8.94e-06	4	43	2	16603237
Pubmed	Models for discovery of targeted therapy in genetic epileptic encephalopathies.	SCN1A SCN8A	8.94e-06	4	43	2	28742937
Pubmed	MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation.	P2RY12 P2RY2	1.49e-05	5	43	2	25972159
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN9A	1.49e-05	5	43	2	8812438
Pubmed	Coordinate pathways for nucleotide and EGF signaling in cultured adult neural progenitor cells.	P2RY13 P2RY2	1.49e-05	5	43	2	19549686
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN8A SCN9A	1.49e-05	5	43	2	22875929
Pubmed	The Sensory Coding of Warm Perception.	TRPA1 TRPM2	1.49e-05	5	43	2	32208171
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN4A SCN8A	1.49e-05	5	43	2	17724025
Pubmed	Differential left-to-right atria gene expression ratio in human sinus rhythm and atrial fibrillation: Implications for arrhythmogenesis and thrombogenesis.	P2RY12 RYR2	1.49e-05	5	43	2	27494721
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN8A SCN9A	2.23e-05	6	43	2	16029194
Pubmed	Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.	P2RY2 PIEZO1	2.23e-05	6	43	2	27797339
Pubmed	H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.	KDM3B KDM3A	2.23e-05	6	43	2	32679061
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	TRPA1 SCN8A	2.23e-05	6	43	2	23711479
Pubmed	Gene-environment interaction in the etiology of mathematical ability using SNP sets.	GUCY1A2 DNAH5	3.12e-05	7	43	2	20978832
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN8A	3.12e-05	7	43	2	25818041
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	SCN1A SCN8A	3.12e-05	7	43	2	15272007
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH5 DNAH17	3.12e-05	7	43	2	31178125
Pubmed	Significant determinants of mouse pain behaviour.	TRPA1 SCN9A	4.16e-05	8	43	2	25101983
Pubmed	Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.	SCN1A SCN4A	4.16e-05	8	43	2	9412493
Pubmed	Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.	SCN1A SCN8A	5.35e-05	9	43	2	17884088
Pubmed	ZMYND10 functions in a chaperone relay during axonemal dynein assembly.	DNAH5 DNAH17	6.68e-05	10	43	2	29916806
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN8A	9.78e-05	12	43	2	30175250
Pubmed	Selective impairment of P2Y signaling by prostaglandin E2 in macrophages: implications for Ca2+-dependent responses.	P2RY13 P2RY12	1.15e-04	13	43	2	23479225
Pubmed	Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.	TRPA1 SCN9A	1.15e-04	13	43	2	35904071
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	KDM3B REV3L IL17RD BABAM2 RYR2 NXF5	1.27e-04	638	43	6	31182584
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH5 DNAH17	1.35e-04	14	43	2	9373155
Pubmed	Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.	P2RY13 P2RY12	1.77e-04	16	43	2	27721240
Pubmed	Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.	TRPA1 TRPM2	2.26e-04	18	43	2	31911949
Pubmed	ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.	TRPA1 SCN9A	3.09e-04	21	43	2	25369838
Pubmed	Glucocorticoid receptor is required for foetal heart maturation.	HSD11B2 RYR2	3.40e-04	22	43	2	23595884
Pubmed	Mapping the expression of transient receptor potential channels across murine placental development.	TRPA1 TRPM2	4.05e-04	24	43	2	33884443
Pubmed	International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.	TRPA1 TRPM2	4.40e-04	25	43	2	16382100
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3B KDM3A TSR1 CECR2 PIEZO1	4.77e-04	529	43	5	14621295
Pubmed	An introduction to TRP channels.	TRPA1 TRPM2	5.14e-04	27	43	2	16460286
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	KDM3B NOP56 IL17RD TNS1 PIEZO1	5.79e-04	552	43	5	10737800
Pubmed	Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs.	FAM106C FAM106A	5.93e-04	29	43	2	11997339
Pubmed	Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.	TRPA1 TRPM2	7.69e-04	33	43	2	30037926
Pubmed	A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.	TRPA1 TRPM2	7.69e-04	33	43	2	19834762
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM3B KDM3A	7.69e-04	33	43	2	26864203
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KDM3B KDM3A NOP56 TSR1	8.11e-04	339	43	4	30415952
Pubmed	Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.	NOD1 PTGDR	1.02e-03	38	43	2	19264973
Interaction	SCN11A interactions	SCN1A SCN8A SCN9A	3.50e-06	15	41	3	int:SCN11A
Interaction	CACNA1D interactions	SCN1A RYR2 SCN9A	1.54e-05	24	41	3	int:CACNA1D
Interaction	SNTA1 interactions	GUCY1A2 SCN1A RYR2 SCN4A	6.07e-05	105	41	4	int:SNTA1
Interaction	KIAA2013 interactions	ACKR2 RNF139 P2RY12 P2RY2	8.95e-05	116	41	4	int:KIAA2013
Interaction	SCN4B interactions	SCN1A SCN8A	1.12e-04	8	41	2	int:SCN4B
Interaction	SCN5A interactions	SCN1A SCN8A SCN9A	1.19e-04	47	41	3	int:SCN5A
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN4A SCN8A SCN9A	1.15e-09	9	33	4	1203
GeneFamily	Purinergic receptors P2Y	P2RY13 P2RY12 P2RY2	6.59e-07	10	33	3	213
GeneFamily	Dyneins, axonemal	DNAH5 DNAH17	4.32e-04	17	33	2	536
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM3B KDM3A	8.70e-04	24	33	2	485
GeneFamily	Transient receptor potential cation channels	TRPA1 TRPM2	1.19e-03	28	33	2	249
Coexpression	GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_UP	CYB561D1 TRPA1 DNAH5 SCN8A NXF5	1.27e-05	194	41	5	M4152
Coexpression	GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP	KDM3A ACKR2 NOD1 REV3L RNF139	1.47e-05	200	41	5	M7841
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	5.37e-07	165	43	5	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	6.78e-07	173	43	5	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUOX1 PTGDR DNAH5 ABCA8 SCN8A	7.38e-07	176	43	5	e08e7a6dd0208acfbb8646d71915af822a64b5de
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUOX1 PTGDR DNAH5 ABCA8 SCN8A	7.38e-07	176	43	5	b8264cdda75c5145d8bf8ae00b3e05393fe9a92b
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUOX1 PTGDR DNAH5 ABCA8 SCN8A	7.38e-07	176	43	5	4aee9fdada077db7e531684ab938153f84dc8146
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	8.95e-07	183	43	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	9.96e-07	187	43	5	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	1.08e-06	190	43	5	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPR20 GUCY1A2 TNS1 KCNQ4 RYR2	1.08e-06	190	43	5	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMBT1 ST3GAL6 NIBAN3 KCNQ4	1.66e-05	159	43	4	f0611a7bf15e2f7dfe828dd247650a30b3d6d44d
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMBT1 ST3GAL6 NIBAN3 KCNQ4	1.84e-05	163	43	4	e04de78a52cc886623689a913f7852200a77605b
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMBT1 ST3GAL6 NIBAN3 KCNQ4	1.84e-05	163	43	4	8509b87748ec460992ae6cedbb155e1c6f6e2e48
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIBAN3 KCNQ4 CECR2 SCN4A	1.97e-05	166	43	4	6842735750dcb361e4c9844f05233b0fbb879652
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY12 SMC1B TRPM2	2.07e-05	168	43	4	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY12 SMC1B TRPM2	2.07e-05	168	43	4	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY12 SMC1B TRPM2	2.11e-05	169	43	4	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	droplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 TRPA1 P2RY12 TNS1	2.11e-05	169	43	4	7962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	GUCY1A2 TNS1 KCNQ4 RYR2	2.21e-05	171	43	4	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 P2RY12 ABCA8 SCN9A	2.27e-05	172	43	4	bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 KCNQ4 RYR2	2.32e-05	173	43	4	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 GPR20 P2RY12 TNS1	2.48e-05	176	43	4	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIBAN3 KCNQ4 RYR2 SCN4A	2.48e-05	176	43	4	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 GPR20 P2RY12 TNS1	2.48e-05	176	43	4	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR20 GUCY1A2 TNS1 KCNQ4	2.53e-05	177	43	4	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN1A SCN9A	2.53e-05	177	43	4	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR20 TRPA1 GUCY1A2 CECR2	2.65e-05	179	43	4	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	DUOX1 DMBT1 CECR2 SCN1A	2.71e-05	180	43	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 RYR2	2.77e-05	181	43	4	451b87ac95154bb80018b8dd245b4a6389d81411
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NIBAN3 KCNQ4 CECR2 SCN4A	2.83e-05	182	43	4	8737142aa4c8301fb5b0ad5bef596471ac316743
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN1A SCN9A	2.83e-05	182	43	4	ecb5624c9074cc6449fad961df54c926c2681d54
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-Zbtb32+_B_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NIBAN3 KCNQ4 CECR2 SCN4A	2.83e-05	182	43	4	632014a6e042d09302f4631ca3a1da36af7a7c98
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR20 GUCY1A2 TNS1 RYR2	3.08e-05	186	43	4	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 RYR2	3.14e-05	187	43	4	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	REV3L GUCY1A2 TNS1 ABCA8	3.14e-05	187	43	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	DMBT1 DNAH5 SCN1A SCN9A	3.21e-05	188	43	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GPR20 GUCY1A2 TNS1 RYR2	3.21e-05	188	43	4	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPG DMBT1 HSD11B2 MRPS28	3.27e-05	189	43	4	45b9d00a4968fb22207d95228cdcf022afe1e50b
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPG DMBT1 HSD11B2 MRPS28	3.27e-05	189	43	4	8382d331e01e83591ba9c8ea83edbf2436c18b17
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	DUOX1 DMBT1 DNAH5 SCN1A	3.27e-05	189	43	4	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 GUCY1A2 KCNQ4 SCN9A	3.34e-05	190	43	4	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR20 GUCY1A2 TNS1 RYR2	3.41e-05	191	43	4	8e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR20 GUCY1A2 TNS1 RYR2	3.41e-05	191	43	4	1626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPR20 GUCY1A2 TNS1 RYR2	3.41e-05	191	43	4	716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	DUOX1 DMBT1 CECR2 SCN1A	3.48e-05	192	43	4	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	DUOX1 DNAH5 CECR2 SCN1A	3.48e-05	192	43	4	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 DMBT1 CECR2 SCN1A	3.55e-05	193	43	4	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN1A SCN9A	3.55e-05	193	43	4	66af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	DUOX1 DMBT1 CECR2 SCN1A	3.55e-05	193	43	4	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	distal-Hematologic-IGSF21+_Dendritic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	P2RY13 P2RY12 SMC1B TRPM2	3.55e-05	193	43	4	48ce11778252ae2ef902b30816061b59a3c81695
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 DMBT1 CECR2 SCN1A	3.55e-05	193	43	4	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN1A SCN9A	3.55e-05	193	43	4	cdc44bf6f5436eb8a2d4720fe011dcb85ccecf87
ToppCell	distal-Hematologic-IGSF21+_Dendritic\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	P2RY13 P2RY12 TRPM2 SCN9A	3.85e-05	197	43	4	a357ee2ba9100dfaeba9ecae8138a2776bb54b0b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 ST3GAL6 CECR2 SCN1A	3.93e-05	198	43	4	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 ST3GAL6 CECR2 SCN1A	3.93e-05	198	43	4	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	mLN-(5)_Dendritic_cell\|mLN / shred on region, Cell_type, and subtype	P2RY13 ST3GAL6 P2RY2 SCN9A	4.00e-05	199	43	4	4feecf533e29a1a558f1018a2e8f7bfa7b9d3864
ToppCell	mLN-Dendritic_cell\|mLN / Region, Cell class and subclass	P2RY13 ST3GAL6 P2RY2 SCN9A	4.00e-05	199	43	4	597412beae1324b9c43ca2bb96c4cb645c19f3e9
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN1A SCN9A	4.00e-05	199	43	4	8d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR20 GUCY1A2 KCNQ4 RYR2	4.08e-05	200	43	4	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	GPR20 GUCY1A2 TNS1 RYR2	4.08e-05	200	43	4	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GPR20 GUCY1A2 TNS1 RYR2	4.08e-05	200	43	4	8158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPR20 GUCY1A2 TNS1 RYR2	4.08e-05	200	43	4	522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GPR20 GUCY1A2 TNS1 RYR2	4.08e-05	200	43	4	600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPR20 GUCY1A2 KCNQ4 RYR2	4.08e-05	200	43	4	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GPR20 GUCY1A2 TNS1 RYR2	4.08e-05	200	43	4	94f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCell	Lymphoid-B_cells_(cycle)\|World / shred on cell class and cell subclass (v4)	NCAPG NOP56 NIBAN3	1.68e-04	111	43	3	df23af931ce0258ce97d6b4c7125ae1ab16a7eaa
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRPA1 DNAH5 NIBAN3	1.72e-04	112	43	3	96038a5240b89f2f6fd26ec5403ce1e23b01b266
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Myxofibrosarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	ACKR2 NOD1 ABCA8	2.27e-04	123	43	3	12b87d06e62f142e18424aae5c87454e78e713f0
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	P2RY13 TRPA1 P2RY12	2.55e-04	128	43	3	cfc73cb803ba50a4a8709e19e70e1e399118c849
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-6\|TCGA-Thryoid / Sample_Type by Project: Shred V9	ST3GAL6 ABCA8 SCN4A	2.80e-04	132	43	3	b7611c6a5c86908132e7ab3e41d67277e8142db1
ToppCell	TCGA-Thryoid\|World / Sample_Type by Project: Shred V9	DUOX1 NOD1 SCN4A	3.18e-04	138	43	3	8cbae2ec9a51712bed5b4e5f9f834ecccb6b7a47
ToppCell	NS-critical-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCAPG IL17RD NIBAN3	3.61e-04	144	43	3	0fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMBT1 SCN1A SCN9A	3.68e-04	145	43	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DNAH5 ABCA8 SCN1A	3.99e-04	149	43	3	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DNAH5 ABCA8 SCN1A	3.99e-04	149	43	3	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	TNS1 KCNQ4 RYR2	4.31e-04	153	43	3	ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3\|TCGA-Thryoid / Sample_Type by Project: Shred V9	ACKR2 CECR2 RYR2	4.39e-04	154	43	3	4e9203c220a44c70cd7979796a0b461991422257
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYB561D1 NCAPG NOP56	4.39e-04	154	43	3	e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 P2RY12 TRPM2	4.56e-04	156	43	3	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOP56 NIBAN3 SCN4A	4.73e-04	158	43	3	66c011e9de002224f70725dfe8e7871c8d304492
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 GUCY1A2 ABCA8	4.82e-04	159	43	3	cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPR20 GUCY1A2 ABCA8	4.82e-04	159	43	3	a75ab494959575143cefdaec99e7aee3f318d559
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NIBAN3 CECR2 SCN4A	5.00e-04	161	43	3	7af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPG NIBAN3 CECR2	5.00e-04	161	43	3	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NIBAN3 CECR2 SCN4A	5.00e-04	161	43	3	98be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCell	droplet-Bladder-nan-3m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 ST3GAL6 P2RY12	5.09e-04	162	43	3	0cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ACKR2 ABCA8 SCN9A	5.09e-04	162	43	3	7f9385aa749bfb2fa9fee6939fe46d946bc21d31
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIBAN3 CECR2 SCN4A	5.18e-04	163	43	3	2a561aa4518cf52d8470eff083b84f942a2b2b5d
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTGDR DNAH5 SCN1A	5.27e-04	164	43	3	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL6 ABCA8 SCN9A	5.27e-04	164	43	3	57301178e420983c0cb72178e288a3a0449fdda3
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTGDR DNAH5 SCN1A	5.27e-04	164	43	3	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAPG NIBAN3 CECR2	5.37e-04	165	43	3	953c8242a81a39ade63ac8e5b34fe58575771746
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 GUCY1A2 P2RY12	5.37e-04	165	43	3	4cdd80580d5638fd649280ba3893251c2f898f3f
ToppCell	NS-control-d_0-4-Myeloid-pDC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NIBAN3 TRPM2 SCN9A	5.37e-04	165	43	3	8b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P2RY13 GUCY1A2 P2RY12	5.37e-04	165	43	3	c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCell	control-Myeloid-pDC\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NIBAN3 TRPM2 SCN9A	5.37e-04	165	43	3	243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 ABCA8 RYR2	5.46e-04	166	43	3	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	P2RY12 ABCA8 SCN9A	5.46e-04	166	43	3	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	NCAPG IL17RD ABCA8	5.46e-04	166	43	3	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	P2RY12 ABCA8 SCN9A	5.46e-04	166	43	3	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 ABCA8 RYR2	5.46e-04	166	43	3	7c2eee0a4f45795a956acf936b85bdb35f1b1624
Drug	AC1L1IZE	P2RY13 P2RY12 P2RY2 DNAH5 RYR2 DNAH17	1.66e-07	131	43	6	CID000004799
Drug	spiradoline	PTGDR BABAM2 SCN4A SCN9A	1.70e-06	46	43	4	CID000005620
Drug	isoproterenol	P2RY13 GUCY1A2 PTGDR P2RY12 P2RY2 BABAM2 RYR2 SCN4A SCN9A	3.57e-06	669	43	9	CID000003779
Drug	bepridil	TRPA1 KCNQ4 RYR2 SCN4A SCN9A	3.90e-06	126	43	5	CID000002351
Drug	Zonisamide	SCN1A SCN4A SCN9A	4.19e-06	17	43	3	DB00909
Drug	AC1L1IO7	P2RY13 RNF139 P2RY12 P2RY2	1.03e-05	72	43	4	CID000000194
Drug	N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide	SCN4A SCN9A	1.04e-05	3	43	2	ctd:C561228
Drug	diethylene glycol	ACKR2 TRPA1 SCN4A SCN9A	1.91e-05	84	43	4	CID000008117
Drug	AC1L1HK7	HSD11B2 PTGDR	2.09e-05	4	43	2	CID000004166
Drug	NSC7524	TRPA1 PTGDR RYR2 SCN4A SCN9A	2.32e-05	182	43	5	CID000005657
Drug	PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A	DMBT1 HSD11B2 TNS1 DNAH17 SCN4A	3.24e-05	195	43	5	6379_UP
Drug	Captopril [62571-86-2]; Up 200; 17.2uM; PC3; HT_HG-U133A	DMBT1 GUCY1A2 TNS1 RYR2 DNAH17	3.40e-05	197	43	5	4585_UP
Drug	Propoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A	DUOX1 NOD1 ABCA8 SCN4A TRPM2	3.48e-05	198	43	5	3583_UP
Drug	Chlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	GUCY1A2 ST3GAL6 TNS1 ABCA8 RYR2	3.56e-05	199	43	5	3198_UP
Drug	isradipine	TRPA1 RYR2 SCN4A SCN9A	3.79e-05	100	43	4	CID000003784
Drug	Ap6A	P2RY13 P2RY12 P2RY2	4.29e-05	36	43	3	CID000123694
Drug	APETx1, Anthopleura elegantissima	SCN4A SCN8A	5.20e-05	6	43	2	ctd:C475726
Drug	lamotrigine	TRPA1 RYR2 SCN4A SCN9A	6.77e-05	116	43	4	CID000003878
Drug	I pN	ACKR2 DMBT1 PTGDR	7.35e-05	43	43	3	CID000012276
Drug	valproate	TRPA1 KCNQ4 RYR2 SCN4A TRPM2 SCN9A	7.63e-05	381	43	6	CID000003121
Drug	tetraethylammonium	GUCY1A2 KCNQ4 ABCA8 SCN4A SCN9A	8.01e-05	236	43	5	CID000005413
Drug	aldosterone	HSD11B2 TRPA1 PTGDR RYR2 SCN4A SCN9A	9.56e-05	397	43	6	CID000005839
Drug	Mrs2279	P2RY13 P2RY12	9.69e-05	8	43	2	CID005311301
Drug	lacosamide	KCNQ4 SCN4A SCN9A	1.30e-04	52	43	3	CID000219078
Drug	AC1N1QTU	P2RY13 P2RY12 P2RY2	1.38e-04	53	43	3	CID003985498
Drug	tetradotoxin	P2RY13 GUCY1A2 P2RY12 SCN4A SCN8A SCN9A	1.44e-04	428	43	6	CID000020382
Drug	AC1L1DKE	P2RY13 P2RY12 P2RY2	1.54e-04	55	43	3	CID000002388
Drug	NSC36900	P2RY13 P2RY12 P2RY2	1.62e-04	56	43	3	CID000235484
Drug	8-SPT	P2RY13 P2RY12 P2RY2	1.71e-04	57	43	3	CID000001908
Drug	RH-3421	SCN4A SCN9A	1.90e-04	11	43	2	CID000108039
Drug	chloroacetylajmaline	SCN4A SCN9A	1.90e-04	11	43	2	CID000038681
Drug	U46619	TRPA1 GUCY1A2 PTGDR P2RY12 RYR2	1.94e-04	285	43	5	CID000005618
Drug	procaine	TRPA1 RYR2 SCN4A SCN9A	1.97e-04	153	43	4	CID000004914
Drug	Ado-5'-PP[S	P2RY13 P2RY12 P2RY2	1.99e-04	60	43	3	CID005310995
Drug	prasugrel	P2RY13 HSD11B2 P2RY12	2.09e-04	61	43	3	CID006918456
Drug	8-phenyltheophylline	P2RY13 P2RY12 P2RY2	2.20e-04	62	43	3	CID000001922
Drug	methylglucamine	SCN4A SCN8A SCN9A	2.20e-04	62	43	3	CID000004049
Drug	acetophenone	TRPA1 P2RY2	2.27e-04	12	43	2	ctd:C038699
Drug	Ro 22-9194	SCN4A SCN9A	2.27e-04	12	43	2	CID000129209
Drug	resiniferatoxin	TRPA1 SCN4A SCN9A	2.64e-04	66	43	3	CID000104826
Drug	Up4dC	P2RY13 P2RY12	2.68e-04	13	43	2	CID000192707
Drug	2-MeSAMP	P2RY13 P2RY12	2.68e-04	13	43	2	CID000189762
Drug	NSC-53396	PTGDR RYR2	2.68e-04	13	43	2	CID000037595
Drug	CID6432355	SCN4A SCN9A	2.68e-04	13	43	2	CID006432355
Drug	AC1LCJM3	SCN4A SCN9A	2.68e-04	13	43	2	CID000631640
Drug	carbachol	NOD1 TRPA1 GUCY1A2 PTGDR P2RY2 RYR2 TRPM2	2.79e-04	688	43	7	CID000002551
Drug	gabapentin	TRPA1 RYR2 SCN4A SCN9A	2.88e-04	169	43	4	CID000003446
Drug	verapamil	TRPA1 KCNQ4 ABCA8 RYR2 SCN4A SCN9A	2.99e-04	490	43	6	CID000002520
Drug	A3P5PS	P2RY12 P2RY2	3.13e-04	14	43	2	CID005310943
Drug	lorcainide	SCN4A SCN9A	3.13e-04	14	43	2	CID000042883
Drug	octylguanidine	SCN4A SCN9A	3.13e-04	14	43	2	CID000030621
Drug	Digocin	PTGDR ABCA8 RYR2	3.14e-04	70	43	3	CID000003062
Drug	riluzole	TRPA1 RYR2 SCN4A SCN9A	3.22e-04	174	43	4	CID000005070
Drug	flecainide	RYR2 SCN4A SCN9A	3.28e-04	71	43	3	CID000003355
Drug	SAHA; Down 200; 10uM; HL60; HT_HG-U133A	KDM3B ST3GAL6 P2RY2 TRPM2	3.37e-04	176	43	4	6179_DN
Drug	3'-AMP	P2RY13 P2RY12 P2RY2	3.42e-04	72	43	3	CID000041211
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; HL60; HT_HG-U133A	NOD1 P2RY2 TNS1 TRPM2	3.51e-04	178	43	4	6193_DN
Drug	AC1NE3N8	P2RY12 P2RY2 SCN4A SCN9A	3.51e-04	178	43	4	CID004636050
Drug	sotalol	KCNQ4 SCN4A SCN9A	3.56e-04	73	43	3	CID000005253
Drug	carbamazepine	BABAM2 SCN4A TRPM2 SCN9A	3.59e-04	179	43	4	CID000002554
Drug	trimethyloxonium	SCN4A SCN9A	3.60e-04	15	43	2	CID000093245
Drug	AC1L1W4O	SCN4A SCN9A	3.60e-04	15	43	2	CID000036625
Drug	HFBA	ACKR2 HSD11B2	3.60e-04	15	43	2	CID000067643
Drug	Catecholamines	HSD11B2 SCN9A	3.60e-04	15	43	2	ctd:D002395
Drug	adenine	P2RY13 REV3L PTGDR P2RY12 P2RY2 RYR2	3.70e-04	510	43	6	CID000000190
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A	DMBT1 TRPA1 GUCY1A2 TNS1	3.98e-04	184	43	4	4369_UP
Drug	AC1N5WL5	P2RY13 P2RY12 P2RY2	4.01e-04	76	43	3	CID004250634
Drug	Mebendazole [31431-39-7]; Down 200; 13.6uM; HL60; HT_HG-U133A	P2RY2 TSR1 TNS1 BABAM2	4.07e-04	185	43	4	2338_DN
Drug	Ketoconazole [65277-42-1]; Up 200; 7.6uM; HL60; HT_HG-U133A	ACKR2 BABAM2 RYR2 DNAH17	4.41e-04	189	43	4	1285_UP
Drug	ATP,Gamma S	P2RY13 P2RY12 P2RY2 SMC1B	4.41e-04	189	43	4	CID000002028
Drug	pioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A	DMBT1 NOP56 BABAM2 SCN9A	4.59e-04	191	43	4	7088_UP
Drug	articaine	SCN4A SCN9A	4.65e-04	17	43	2	CID000032169
Drug	PPNDS	P2RY13 P2RY12	4.65e-04	17	43	2	CID005961627
Drug	lifarizine	SCN4A SCN9A	4.65e-04	17	43	2	CID000071336
Drug	sumatriptan	P2RY13 P2RY12 P2RY2	4.66e-04	80	43	3	CID000005358
Drug	Adenosine Triphosphate	P2RY13 P2RY2 ABCA8 RYR2	4.77e-04	193	43	4	ctd:D000255
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	ST3GAL6 TNS1 RYR2 SCN9A	4.86e-04	194	43	4	4248_DN
Drug	Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A	GPR20 DNAH17 TRPM2 SCN8A	4.96e-04	195	43	4	4402_UP
Drug	Carcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A	DMBT1 TRPA1 TNS1 SCN4A	5.05e-04	196	43	4	4225_UP
Drug	Proadifen hydrochloride [62-68-0]; Up 200; 10.2uM; PC3; HT_HG-U133A	DMBT1 TRPA1 DNAH17 SCN9A	5.05e-04	196	43	4	5807_UP
Drug	Aminocaproic acid [60-32-2]; Up 200; 30.4uM; MCF7; HT_HG-U133A	ACKR2 NOD1 GUCY1A2 ST3GAL6	5.05e-04	196	43	4	6501_UP
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A	KDM3A DMBT1 SCN1A RYR2	5.05e-04	196	43	4	4317_UP
Drug	Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; PC3; HT_HG-U133A	DUOX1 GPR20 ABCA8 RYR2	5.15e-04	197	43	4	4668_UP
Drug	CGX 0596987; Up 200; 20uM; MCF7; HT_HG-U133A	TNS1 SCN1A RYR2 SCN8A	5.15e-04	197	43	4	6412_UP
Drug	Pivampicillin [33817-20-8]; Up 200; 8.6uM; PC3; HT_HG-U133A	P2RY13 DMBT1 TNS1 SCN4A	5.15e-04	197	43	4	5046_UP
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; PC3; HT_HG-U133A	ST3GAL6 TSR1 RYR2 SCN8A	5.15e-04	197	43	4	6322_UP
Drug	moricizine	SCN4A SCN9A	5.23e-04	18	43	2	CID000034632
Drug	Scorpion Venoms	SCN4A SCN9A	5.23e-04	18	43	2	ctd:D012604
Drug	Delcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A	DMBT1 TNS1 TRPM2 SCN8A	5.25e-04	198	43	4	6033_UP
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	DUOX1 DMBT1 GPR20 DNAH17	5.25e-04	198	43	4	2293_UP
Drug	Tribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A	ST3GAL6 RYR2 DNAH17 SCN9A	5.25e-04	198	43	4	6328_UP
Drug	Dioxybenzone [131-53-3]; Up 200; 16.4uM; HL60; HT_HG-U133A	DMBT1 GUCY1A2 TNS1 DNAH17	5.35e-04	199	43	4	3101_UP
Drug	Dehydroisoandosterone 3-acetate [853-23-6]; Up 200; 12.2uM; HL60; HT_HG-U133A	GPR20 TRPA1 TNS1 DNAH17	5.35e-04	199	43	4	3097_UP
Drug	Probucol [23288-49-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	NOD1 GUCY1A2 TNS1 ABCA8	5.35e-04	199	43	4	4666_UP
Drug	Sodium	HSD11B2 SCN8A SCN9A	5.37e-04	84	43	3	ctd:D012964
Drug	forskolin from Coleus forskohlii	P2RY13 HSD11B2 GUCY1A2 P2RY12 P2RY2 RYR2 SCN4A SCN9A	5.41e-04	1013	43	8	CID000003413
Drug	N6-Me-dAdo	P2RY12 P2RY2	5.84e-04	19	43	2	CID000168948
Drug	diprafenone	SCN4A SCN9A	5.84e-04	19	43	2	CID000071249
Drug	menthol	TRPA1 P2RY2 TRPM2	5.95e-04	87	43	3	CID000001254
Drug	reactive blue 2	P2RY13 P2RY12 P2RY2	5.95e-04	87	43	3	CID000656725
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN4A SCN8A SCN9A	6.04e-10	10	40	4	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN4A SCN8A SCN9A	6.04e-10	10	40	4	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN4A SCN8A SCN9A	1.42e-09	12	40	4	DOID:0060170 (implicated_via_orthology)
Disease	Early Infantile Epileptic Encephalopathy 6	SCN1A SCN9A	1.79e-06	2	40	2	C4551549
Disease	anxiety disorder (implicated_via_orthology)	KDM3B SCN1A SCN9A	3.49e-06	22	40	3	DOID:2030 (implicated_via_orthology)
Disease	B Virus Infection	SCN8A SCN9A	5.37e-06	3	40	2	C0037140
Disease	Postherpetic neuralgia	SCN8A SCN9A	5.37e-06	3	40	2	C0032768
Disease	Herpesviridae Infections	SCN8A SCN9A	5.37e-06	3	40	2	C0019372
Disease	Early Childhood Epilepsy, Myoclonic	SCN1A SCN9A	4.99e-05	8	40	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	SCN1A SCN9A	4.99e-05	8	40	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	SCN1A SCN9A	4.99e-05	8	40	2	C0338479
Disease	Myoclonic Encephalopathy	SCN1A SCN9A	4.99e-05	8	40	2	C0438414
Disease	Benign Infantile Myoclonic Epilepsy	SCN1A SCN9A	4.99e-05	8	40	2	C0751120
Disease	Myoclonic Absence Epilepsy	SCN1A SCN9A	4.99e-05	8	40	2	C0393703
Disease	Myoclonic Epilepsy	SCN1A SCN9A	6.41e-05	9	40	2	C0014550
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN9A	6.41e-05	9	40	2	C3502809
Disease	epilepsy (implicated_via_orthology)	SCN1A SCN4A SCN8A SCN9A	7.02e-05	163	40	4	DOID:1826 (implicated_via_orthology)
Disease	Epilepsy, Myoclonic, Infantile	SCN1A SCN9A	8.01e-05	10	40	2	C0917800
Disease	Myoclonic Astatic Epilepsy	SCN1A SCN9A	9.78e-05	11	40	2	C0393702
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN9A	1.38e-04	13	40	2	C0751122
Disease	Asthma	HSD11B2 TRPA1 DNAH5	1.76e-04	80	40	3	C0004096
Disease	diverticular disease	P2RY12 TNS1 BABAM2 PIEZO1	2.91e-04	236	40	4	EFO_0009959
Disease	Epilepsy	SCN1A SCN8A SCN9A	4.39e-04	109	40	3	C0014544
Disease	Grey matter density measurement	GUCY1A2 SCN1A	9.78e-04	34	40	2	EFO_0010306
Disease	shoulder impingement syndrome	GUCY1A2 ABCA8	1.10e-03	36	40	2	EFO_1001178
Disease	asthma (is_implicated_in)	NOD1 PTGDR P2RY12	1.26e-03	157	40	3	DOID:2841 (is_implicated_in)
Disease	osteoarthritis, knee	NOD1 BABAM2 PIEZO1	1.29e-03	158	40	3	EFO_0004616

Protein segments in the cluster

Peptide	Gene	Start	Entry
CFSPILYAFSSHRFR	ACKR2	306	O00590
PEHSLFFFCSRKARI	CYB561D1	76	Q8N8Q1
LHEAVRFSFAFSFPR	FAM106A	51	Q4KMX7
VLIIFLVCFTPFHAR	GPR20	246	Q99678
RFLQAFFISHCLPRA	HSD11B2	361	P80365
PAIAHFCSLFRTAFR	CECR2	21	Q9BXF3
FRSPVFRIFFHKIFI	PTGDR	326	Q13258
FPLFLQHPFRRHLCF	NIBAN3	191	Q86XR2
FALIQLPRFHIFFLV	DUOX1	1241	Q9NRD9
LHEAVRFSFAFSFPR	FAM106C	51	P0CH98
KFHSIVRLVAFCPFA	NOP56	41	O00567
HPFFFRTRACDLLLQ	IL17RD	176	Q8NFM7
RFRFARKPFCVIDFI	KCNQ4	166	P56696
FTPVDFHYIRNRACF	NXF5	41	Q9H1B4
PLFCWIIFRCFQHFR	NOD1	391	Q9Y239
ACRFFHFRRLIFTRK	KDM3B	936	Q7LBC6
IIAVFFICFVPFHFA	P2RY12	241	Q9H244
FICFVPFHFARIPYT	P2RY12	246	Q9H244
LAVFALCFLPFHVTR	P2RY2	251	P41231
VAVFFVCFAPFHFAR	P2RY13	261	Q9BPV8
QKDSPVFCRFFHFRR	KDM3A	561	Q9Y4C1
TRFFTFHFILPFIIA	MT-CYB	176	P00156
FCFLVHIDLPLFFPR	BABAM2	306	Q9NXR7
SRLQRHFCVFAVSFP	DNAH17	2581	Q9UFH2
AFHFLNRFPSVYLRC	DMBT1	2346	Q9UGM3
HFVASVFRGFFRIIC	RYR2	4296	Q92736
RLCFPRFFFVSDPAL	DNAH5	1711	Q8TE73
HSLFQTSFVFRLPFC	OR10G6	176	Q8NH81
LRISINTFCRAFPFH	GUCY1A2	316	P33402
FRRHFPVLFVSACLF	RNF139	386	Q8WU17
AAESHFLRVFLFFRP	MRPS28	11	Q9Y2Q9
DFFHSFLIVFRILCG	SCN4A	746	P35499
NDFFHSFLIVFRVLC	SCN9A	911	Q15858
FASLLRFHQFHPFLC	ST3GAL6	51	Q9Y274
RFHQFHPFLCAADFR	ST3GAL6	56	Q9Y274
DFFHSFLIVFRVLCG	SCN1A	936	P35498
PFLHFIIFLFTLRCL	ABCA8	1206	O94911
VQLRHCLGVFFPVFA	NCAPG	746	Q9BPX3
FHCGFRRFRASPLFS	TSR1	616	Q2NL82
LFHIFCFLFCTGEIR	TRPA1	1016	O75762
FHVLHQRFPLFTFRV	REV3L	2486	O60673
LLFAVHSFRPAPFFV	SMC1B	1136	Q8NDV3
ARARAFFTAPVVVFH	TRPM2	786	O94759
FFRRHYPLNTVTFCD	TNS1	1656	Q9HBL0
DFFHSFLIVFRVLCG	SCN8A	921	Q9UQD0
CFFFLLLQRRVFLSH	PIEZO1	1291	Q92508