Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class I receptor activity

KIR2DS5 KIR3DL1 KIR3DS1

6.91e-0618423GO:0032393
GeneOntologyMolecularFunctioninhibitory MHC class I receptor activity

KIR2DS5 KIR3DL1

2.81e-0412422GO:0032396
GeneOntologyMolecularFunctionimmune receptor activity

KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.94e-04165424GO:0140375
GeneOntologyMolecularFunctionMHC class Ib protein binding

KIR2DL3 KIR3DL1

5.09e-0416422GO:0023029
GeneOntologyMolecularFunctionMHC class Ib receptor activity

KIR2DL3 KIR3DL1

7.22e-0419422GO:0032394
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP34 USP13 USP54

1.77e-03114423GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP34 USP13 USP54

2.25e-03124423GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP34 USP13 USP54

2.98e-03137423GO:0019783
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

LRCH4 KIR2DS2 PDE4D KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.62e-06615419GO:0002764
GeneOntologyBiologicalProcessestablishment of skin barrier

FLG HRNR FLG2

7.37e-0541413GO:0061436
GeneOntologyCellularComponentkeratohyalin granule

FLG HRNR FLG2

7.52e-085423GO:0036457
GeneOntologyCellularComponentcornified envelope

FLG HRNR FLG2

3.60e-0469423GO:0001533
HumanPhenoTypified by age-related disease onset

DCHS1 TENM4

4.22e-055112HP:0003831
MousePhenoabnormal sternum morphology

DCHS1 HOXA5 HMBOX1 JARID2 KLHL12 TENM4

5.89e-06255266MP:0000157
MousePhenoabnormal pectoral girdle bone morphology

DCHS1 HOXA5 HMBOX1 JARID2 KLHL12 TENM4

1.52e-05301266MP:0004508
Domainig

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

8.69e-09190428PF00047
DomainImmunoglobulin

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

8.69e-09190428IPR013151
DomainIG

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.76e-06421428SM00409
DomainIg_sub

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.76e-06421428IPR003599
DomainFilaggrin

FLG FLG2

4.94e-062422IPR003303
DomainIg-like_dom

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.38e-05503428IPR007110
DomainIg-like_fold

PAPPA2 KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.18e-05706429IPR013783
DomainS100_CABP

FLG HRNR FLG2

2.98e-0527423PS00303
DomainS_100

FLG HRNR FLG2

2.98e-0527423PF01023
DomainS100_Ca-bd_sub

FLG HRNR FLG2

3.33e-0528423IPR013787
DomainS100/CaBP-9k_CS

FLG HRNR FLG2

3.33e-0528423IPR001751
DomainS_100

FLG HRNR FLG2

3.33e-0528423SM01394
Domain-

PAPPA2 KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

9.80e-056634282.60.40.10
DomainIG_LIKE

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.01e-04491427PS50835
DomainUSP_1

USP34 USP13 USP54

5.21e-0470423PS00972
DomainUCH

USP34 USP13 USP54

5.43e-0471423PF00443
DomainUSP_2

USP34 USP13 USP54

5.43e-0471423PS00973
DomainUSP_3

USP34 USP13 USP54

5.66e-0472423PS50235
DomainUSP_dom

USP34 USP13 USP54

5.66e-0472423IPR028889
DomainPeptidase_C19_UCH

USP34 USP13 USP54

5.66e-0472423IPR001394
DomainAlkaline_phosphatase_core

ARSF ALPI

2.20e-0331422IPR017850
DomainAlkaline_Pase-like_a/b/a

ARSF ALPI

2.20e-0331422IPR017849
Domain-

ARSF ALPI

2.20e-03314223.40.720.10
DomainEF_Hand_1_Ca_BS

FLG HRNR FLG2

7.10e-03175423IPR018247
DomainUSP_CS

USP34 USP13

9.67e-0366422IPR018200
DomainEF_HAND_1

FLG HRNR FLG2

1.08e-02204423PS00018
DomainEF_HAND_2

FLG HRNR FLG2

1.50e-02231423PS50222
DomainEF_hand_dom

FLG HRNR FLG2

1.52e-02232423IPR002048
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.49e-0688325M16004
PathwayREACTOME_DAP12_INTERACTIONS

KIR2DS2 KIR2DS1 KIR2DS5 KIR3DS1

3.34e-0646324M27151
PathwayKEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY

KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.31e-05137325M5669
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

KIR2DS2 SIGLEC1 KIR2DL3 KIR2DS1 KIR3DL1

6.32e-05190325M8240
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

KIR2DL2 KIR2DL3 KIR3DL1

1.07e-0441323M13519
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

7.27e-191142719664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.74e-181242720371502
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.74e-181242719936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.74e-181242719181658
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.77e-181342718687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.77e-181342719934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.77e-181342719120281
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

7.54e-181442719875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

7.54e-181442719421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

7.54e-181442715896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542720082646
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542720643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542719326408
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542719926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542719850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542720207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542719493232
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.41e-171542720356536
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642719897003
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642719279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642717868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642718643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642719309280
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642719000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642720670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642719527230
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642720331834
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642720652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642718668235
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.51e-171642720210919
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742720173792
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742719218127
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742720483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742719968064
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742719169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742720878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742720650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742719450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.26e-171742719761533
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.97e-171842719046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.97e-171842719846535
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.97e-171842719630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.97e-171842720519398
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.97e-171842720580654
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-161942718778326
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-161942718571006
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-161942720600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of Paraná.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-161942718848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.69e-162042720193031
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.79e-1694268662091
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.54e-162142719861144
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.72e-162242720492596
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

4.47e-161042612559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

9.82e-161142618830515
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.96e-151242620137308
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.38e-152942720082482
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

6.37e-151442619489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS2 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.37e-151442618945962
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.06e-141542617498266
Pubmed

Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DS1

1.20e-14642517882223
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.45e-143542719683555
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.69e-141642616403292
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.62e-141742619032228
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DS1

2.62e-141742620173784
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

3.92e-141842620200544
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

3.92e-141842620210918
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DS2 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

8.17e-142042620426625
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DS2 KIR2DL2 KIR2DL3 KIR3DL1 KIR3DS1

1.12e-13842517200871
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

1.12e-13842518681957
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1

2.52e-1394257749980
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-131042521206914
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.58e-121242517490516
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR2DL2 KIR2DL3 KIR3DL1 KIR3DS1

1.84e-12442419522772
Pubmed

KIR gene in ethnic and Mestizo populations from Mexico.

KIR2DL2 KIR2DS1 KIR2DS5 KIR3DS1

9.17e-12542416698429
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1

9.17e-12542416112031
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1

9.17e-12542418755860
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR2DS2 KIR2DS1 KIR3DL1 KIR3DS1

2.75e-11642420528243
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DS2 KIR2DL2 KIR2DS5 KIR3DL1

6.41e-11742414607943
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1

6.41e-11742411169255
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

6.41e-1174249430220
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

1.28e-1084249430221
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS2 KIR2DS1 KIR3DL1 KIR3DS1

2.30e-10942418340360
Pubmed

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.

FLG HRNR FLG2

1.64e-09342323403047
Pubmed

Killer cell immunoglobulin-like receptor (KIR) genes in the Basque population: association study of KIR gene contents with type 1 diabetes mellitus.

KIR2DL2 KIR2DS5 KIR3DS1

1.64e-09342316698433
Pubmed

Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

KIR2DS2 KIR2DL2 KIR2DL3

1.64e-09342330696053
Pubmed

Associations of killer cell immunoglobulin- like receptor genes with rheumatoid arthritis.

KIR2DS2 KIR2DL2 KIR2DL3

1.64e-09342322960345
Pubmed

Homozygosity for killer immunoglobin-like receptor haplotype A predicts complete molecular response to treatment with tyrosine kinase inhibitors in chronic myeloid leukemia patients.

KIR2DS2 KIR2DL2 KIR2DS1

1.64e-09342323380384
Pubmed

KIR2DS1, 2DS5, 3DS1 and KIR2DL5 are associated with the risk of head and neck squamous cell carcinoma in Iranians.

KIR2DS1 KIR2DS5 KIR3DS1

1.64e-09342329408295
Pubmed

Lack of killer immunoglobulin-like receptor 2DS2 (KIR2DS2) and KIR2DL2 is associated with poor responses to therapy of recurrent hepatitis C virus in liver transplant recipients.

KIR2DS2 KIR2DL2 KIR2DS1

1.64e-09342319877200
Pubmed

Imputation of KIR Types from SNP Variation Data.

KIR2DS2 KIR2DL2 KIR2DL3

1.64e-09342326430804
Pubmed

Cutting edge: selective expression of inhibitory or activating killer cell Ig-like receptors in circulating CD4+ T lymphocytes.

KIR2DS2 KIR2DL2 KIR2DL3

1.64e-09342318292496
Pubmed

Systemic lupus erythematosus: association with KIR and SLC11A1 polymorphisms, ethnic predisposition and influence in clinical manifestations at onset revealed by ancestry genetic markers in an urban Brazilian population.

KIR2DS2 KIR2DS5 KIR3DS1

6.54e-09442321233146
Pubmed

Activating KIR genes are associated with ankylosing spondylitis in Asian populations.

KIR2DS5 KIR3DL1 KIR3DS1

6.54e-09442318638658
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL2 KIR2DL3 KIR3DL1

6.54e-09442318269867
Pubmed

Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

KIR2DL2 KIR2DL3 KIR2DS1

6.54e-09442326542066
Pubmed

Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility.

KIR2DS2 KIR2DL2 KIR2DL3

6.54e-09442316929347
Pubmed

Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.

KIR2DS1 KIR2DS5 KIR3DS1

6.54e-09442325253288
Pubmed

Polymorphism and domain variability of human killer cell inhibitory receptors.

KIR2DL3 KIR3DL1 KIR3DS1

6.54e-0944239059894
Pubmed

KIR/HLA ligand incompatibility in kidney transplantation.

KIR2DS2 KIR2DL2 KIR2DL3

6.54e-09442318091530
Pubmed

In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.

KIR2DS2 KIR2DS1 KIR2DS5

1.63e-08542319410616
InteractionKIR2DL2 interactions

KIR2DS2 KIR2DL2 KIR3DL1 KIR3DS1

1.15e-0813424int:KIR2DL2
InteractionKIR2DS2 interactions

KIR2DS2 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1

1.28e-0837425int:KIR2DS2
InteractionKIR3DL1 interactions

KIR2DS2 KIR2DL2 KIR3DL1

2.37e-0613423int:KIR3DL1
InteractionKIR2DS3 interactions

KIR2DS2 KIR2DL2 KIR2DS5

9.36e-0620423int:KIR2DS3
InteractionKIR2DS1 interactions

KIR2DS2 KIR2DS1

2.54e-054422int:KIR2DS1
InteractionKIR3DP1 interactions

KIR2DS2 KIR2DS5

2.54e-054422int:KIR3DP1
InteractionKIR3DS1 interactions

FLG KIR2DL2 KIR3DS1

2.66e-0528423int:KIR3DS1
Cytoband19q13.4

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

8.74e-137942719q13.4
Cytoband1q21.3

FLG HRNR FLG2

1.72e-041174231q21.3
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.60e-1618317620
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG HRNR FLG2

1.59e-0773131350
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR2DS2 SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

3.70e-06394317471
GeneFamilyUbiquitin specific peptidases

USP34 USP13 USP54

1.19e-0456313366
GeneFamilyEF-hand domain containing

FLG HRNR FLG2

6.14e-03219313863
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.55e-1049426M40909
CoexpressionGSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

5.66e-07190426M4662
CoexpressionGSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DS1

1.62e-05199425M9885
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 HMBOX1 KIF26A MYCT1

3.80e-0717538598dc3b6f69a29d587f503898f09912700950e3d9
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE4D KIR2DL2 KIR2DL3 KIR3DL1

1.34e-05171384adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 USP13 TENM4 NRK

1.79e-05184384e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 KIF26A MYCT1

2.12e-05192384bcd8876235be503186f119653b39476488c0fa15
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 KIF26A MYCT1

2.12e-05192384f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

HMBOX1 JARID2 PDE4D GPBP1

2.16e-05193384e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DCHS1 HOXA5 KIF26A MYCT1

2.21e-05194384e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP13 PDE4D USP54 DCBLD2

2.44e-051993842dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-6|TCGA-Stomach / Sample_Type by Project: Shred V9

PAPPA2 KIF26A ALPI

7.76e-0597383489f5e12eb67b1850f1f2d7d4b229df1f4ceefe3
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-6|TCGA-Bladder / Sample_Type by Project: Shred V9

FLG FLG2 ARSF

1.72e-04127383d61b71572eab8a850ee8ce54323fb247525006e5
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IQSEC3 KIR2DL3 KIR3DL1

2.30e-04140383a88dbe7bf3e1419e360ab0b8cf24681d3424c3a7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC44A5 SKOR2 ALPI

2.76e-0414938398ae408d2d0347865875ff8bbd89d359decea526
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 FLG2 NRK

3.52e-04162383373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 PDE4D KIR2DL3

3.59e-0416338311cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DCHS1 TENM4 HRNR

3.78e-0416638365dafed953b01a9830b54309af75c7a561e88336
ToppCellHealthy_donor-HSPC|World / disease group, cell group and cell class (v2)

HOXA5 DCBLD2 MYCT1

3.85e-0416738370630ebdfee8171d625811844f8a7c94736d101e
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HMBOX1 SLC44A5 BAIAP2L2

3.85e-041673839a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

HOXA5 DCBLD2 MYCT1

3.92e-0416838390b33962adb77d8326dee403712118398b4d1315
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQSEC3 KIR2DL3 KIR3DL1

3.92e-04168383240ea32b64d86f9216785010d6b237d9adf052c9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQSEC3 KIR2DL3 KIR3DL1

3.92e-04168383b4bb03efb601a61465260f93896c56861c588bef
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 UBE2O MYCT1

3.99e-041693834126b20df9e85f028807482a51e20a300faa74c2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D PRKRIP1 FLG2

3.99e-0416938301a24a8817628125bd004b2be68ffa62c7111f6e
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 UBE2O SLC44A5

3.99e-041693834e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IQSEC3 KIR2DL3 KIR3DL1

3.99e-04169383e7470a5b060881b2a8ce2ab04b0788396aa13889
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

HOXA5 DCBLD2 MYCT1

4.06e-0417038385c476e0bc496445e868a88849960598d97bdea2
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIR2DL3 KIR3DL1 BAIAP2L2

4.20e-04172383e3a8891694343b6b01e80a200ae338d24797e417
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 KIF26A NRK

4.27e-041733837a3115e7cf7e2f345192cde0656a7f0193594a5f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMBOX1 USP54 NRK

4.34e-04174383c58328c2f262506a4518f49f148e29874faf9171
ToppCellsevere-Others-CD34+_GATA2+_cells|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HOXA5 IQSEC3 MYCT1

4.72e-04179383dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP13 SARS2 NRK

5.03e-04183383ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCHS1 KIF26A MYCT1

5.11e-0418438316ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM4 ARSF BAIAP2L2

5.11e-041843839434731f651820b05335085582960f08fbf895de
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HMBOX1 KIF26A MYCT1

5.19e-0418538359acaf025353405948dc34ccccf37ec5c08ea903
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DCHS1 HOXA5 MYCT1

5.19e-04185383dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE4D USP54 SLC44A5

5.27e-041863832ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 MYCT1

5.27e-0418638390d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 DCBLD2 MYCT1

5.27e-0418638360830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 MYCT1

5.27e-041863832cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE4D KIR2DL3 KIR3DL1

5.27e-04186383165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 DCBLD2 MYCT1

5.27e-0418638337860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 DCBLD2 MYCT1

5.27e-04186383baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 TENM4 NRK

5.36e-041873835258674d0346e5c51a4b965efcdc1790c970845d
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

PAPPA2 TENM4 NRK

5.36e-041873832ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA2 PDE4D NRK

5.44e-041883831d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellE12.5-Mesenchymal|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HOXA5 TENM4 NRK

5.44e-041883839778dadc2bd7ded3a723e717d1c8cd3160e99c6c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 USP13 NRK

5.44e-041883832ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 PDE4D NRK

5.52e-04189383e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXA5 KIF26A MYCT1

5.52e-04189383feedac2751ed770f80bc56fec31662b5b3826f58
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

USP13 PDE4D USP54

5.52e-041893830a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 HOXA5 MYCT1

5.61e-041903839d5242759546be0089981ef1877e4ed5f81face5
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D SARS2 KIR3DL1

5.61e-04190383373629dde5eda722424c5e6087763f0c5db67cf4
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

DCHS1 HOXA5 MYCT1

5.61e-04190383bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCellPSB-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIR2DL2 KIR2DL3 KIR3DL1

5.61e-04190383e1b5d76edd4c1b95c0a7b94284a65043ab895e67
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FLG PDE4D GPBP1

5.61e-04190383f6616b3fe7f4962249503c96c06926240066d861
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 TENM4 NRK

5.61e-041903833dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

DCHS1 HOXA5 MYCT1

5.61e-0419038308437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 TENM4 NRK

5.61e-04190383cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXA5 KIF26A MYCT1

5.69e-041913830e8a73f01e3ec95d242c09231bcf3790324d0a67
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA2 TENM4 NRK

5.69e-04191383fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXA5 KIF26A MYCT1

5.69e-04191383b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXA5 KIF26A MYCT1

5.69e-0419138327f23c2254b610abac1a88d0fecff305addde9da
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 KIF26A MYCT1

5.69e-04191383471205494b91be69926dc8159376132bcea0d9b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

USP13 TENM4 NRK

5.69e-04191383963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA2 TENM4 NRK

5.69e-041913830965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

PDE4D USP54 DCBLD2

5.69e-04191383276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXA5 KIF26A MYCT1

5.69e-0419138354bbccc554f43ba2ebdf9ea191b94c8f16081b53
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

JARID2 PDE4D GPBP1

5.78e-04192383916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellmild_COVID-19-gd_T|World / disease group, cell group and cell class (v2)

SLC25A38 PDE4D KIR2DL3

5.78e-041923836912283dbd73285b6e0c653b2dd34c31337b9f1e
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLG KIR3DL1 NRK

5.87e-04193383315840bc48899f3a36d57b19197509de19716e3d
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP34 JARID2 PDE4D

5.87e-04193383779276e775cb2492e8dd36436295a536084a6415
ToppCell3'_v3-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

PDE4D KIR2DL3 KIR3DL1

5.87e-04193383a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCellILEUM-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

N4BP2L1 H6PD GPBP1

5.87e-04193383d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

HOXA5 JARID2 PDE4D

5.96e-0419438328571cf24b8a1d0ffb716167b977d420868cc874
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP13 PDE4D USP54

5.96e-0419438397534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell10x5'v1-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE4D KIR2DL3 KIR3DL1

5.96e-041943835afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD16|blood / Manually curated celltypes from each tissue

PDE4D KIR2DL3 KIR3DL1

5.96e-04194383c34a32f1cfe3e597cb0f91ba5bdd3e114e9f3d2e
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDE4D KIR2DL3 KIR3DL1

5.96e-04194383ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCellT_cells-CD56_dim_CD16+_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

KIR2DL2 KIR2DL3 KIR3DL1

5.96e-04194383335c6c2f3f319d4f19eace62f8826a0f40c130f6
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

PDE4D KIR2DL3 KIR3DL1

5.96e-041943833337042eef91a49f621058785723228cf4dfdad4
ToppCelltumor_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

N4BP2L1 H6PD GPBP1

6.05e-0419538372a7c4beb880390b29f3c5d6dd9dbb082af50fe2
ToppCellASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DCHS1 HOXA5 MYCT1

6.05e-04195383304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCellEndothelial|World / shred by cell class for bronchial biopsy

DCHS1 KIF26A MYCT1

6.05e-04195383f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCell10x5'-blood-Lymphocytic_NK|blood / Manually curated celltypes from each tissue

PDE4D KIR2DL3 KIR3DL1

6.05e-04195383c1db871e8e8e8b8d6a5798bc43eaf54e102b75eb
ToppCellLAM-Lymphoid-NK|LAM / Condition, Lineage and Cell class

KIR2DL2 KIR2DL3 KIR3DL1

6.05e-04195383229374c72acef32b0e915379bdf3c82f351940e2
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE4D KIR2DL3 KIR3DL1

6.14e-0419638364b23d819efddb25024c86f2e1b5dc4159337ddd
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP13 PDE4D USP54

6.14e-041963837e5addaa844e66f8160e05858c341866a80aed23
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

PAPPA2 TENM4 NRK

6.14e-0419638304f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE4D KIR2DL3 KIR3DL1

6.14e-04196383ba46f80d1497eaf4d71b59504106ba4b84e4ff9f
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE4D KIR2DL3 KIR3DL1

6.14e-04196383eb0b711ca6da7b5e5313791c3c3985358e2a222e
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIR2DL2 KIR2DL3 KIR3DL1

6.14e-04196383cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCell367C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HOXA5 KIR2DL3 KIR3DL1

6.14e-04196383c6fac4ead13834483e780188de7d417e5cf37611
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE4D KIR2DL3 KIR3DL1

6.23e-0419738348311c7d85ffabf59fd1685c31c18b3e84a145b5
ToppCellSevere_COVID-19-T/NK-NK|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PDE4D KIR2DL3 KIR3DL1

6.23e-04197383cc20162892b59e48653981f91fc9a0c27064444d
ToppCelltumor_Lung-Endothelial_cells-Tip-like_ECs|tumor_Lung / Location, Cell class and cell subclass

DCHS1 HOXA5 MYCT1

6.23e-04197383353b76ca3e2aa4b8f51396e7121c4baa114083a0
ToppCellSevere-Lymphoid-NK-NK|Severe / Condition, Lineage, Cell class and cell subclass

PDE4D KIR2DL3 KIR3DL1

6.23e-04197383d5b94f9f73e9d050245841b19b046242a32c6258
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE4D KIR2DL3 KIR3DL1

6.23e-04197383a26dd66a6bd08b46657b3a7c41669e206a8887b3
ToppCellBAL-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE4D KIR2DL3 KIR3DL1

6.23e-0419738392f35ea602489efd29ce3a8a186d1f70d65faf40
ToppCellCOVID-19-COVID-19_Convalescent-Others-HSPC|COVID-19_Convalescent / Disease, condition lineage and cell class

HOXA5 DCBLD2 MYCT1

6.23e-04197383c1033a1a8b8b5c8569130aa9405a6e8e65ef7bd0
ToppCellSevere-NK|World / Disease group and Cell class

PDE4D KIR2DL3 KIR3DL1

6.23e-041973831e5fb79385657a467c2d9f942d8cafb8ef7826c9
ToppCellEndothelial-A|World / lung cells shred on cell class, cell subclass, sample id

DCHS1 HOXA5 MYCT1

6.32e-04198383dd096d4b9f428615f927f7df7cbf5cede0e0e605
DrugAC1L1AQK

SIGLEC1 SARS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

8.08e-08119426CID000001105
Drug1c88

SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 NRK

1.14e-07126426CID000444766
DrugD-Au

KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

2.99e-0777425CID000277822
DrugAa1

KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

4.36e-0783425CID009549188
DrugAb-9

KIR2DL2 KIR2DL3 KIR3DL1

7.59e-0621423CID006540280
Drugpristane

SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

8.65e-06152425CID000015979
DrugDNTB

SIGLEC1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

4.69e-05216425CID000015325
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

4.38e-0424382DOID:12365 (is_implicated_in)
Diseasetuberculosis (is_implicated_in)

KIR3DL1 KIR3DS1

5.98e-0428382DOID:399 (is_implicated_in)
Diseasehepatitis C (is_implicated_in)

KIR3DL1 KIR3DS1

5.98e-0428382DOID:1883 (is_implicated_in)
Diseasehuman immunodeficiency virus infectious disease (is_implicated_in)

KIR3DL1 KIR3DS1

1.16e-0339382DOID:526 (is_implicated_in)
Diseasesusceptibility to mumps measurement

UBE2O PDE4D

4.22e-0375382EFO_0008404
Diseasecarnitine measurement

SLC44A5 NRK

4.33e-0376382EFO_0010469

Protein segments in the cluster

PeptideGeneStartEntry
YFTSDHGGHLEARRG

ARSF

341

P54793
SSAVRDSGHRGYSGS

FLG

2676

P20930
YGESGFRHSQHGSVS

FLG

3986

P20930
THGGTYRCFGSFRDS

KIR2DS2

191

P43631
GHRYDGGLDSGFHSV

LRCH4

291

O75427
SYRLASGGDGHFRLH

DCHS1

1581

Q96JQ0
RTTGRRGSGHSEYSD

FLG2

1946

Q5D862
TGDTTRHAHYGYGQS

FLG2

2226

Q5D862
THGGTYRCFGSFRDS

KIR2DL2

191

P43627
THGGTYRCFGSFRDS

KIR2DL3

191

P43628
HRGGYHGGSSRSRSS

GPBP1

86

Q86WP2
GEFSSPRSRHGSGSY

BAIAP2L2

261

Q6UXY1
EHSDKFGRRSSYGGS

HMBOX1

56

Q6NT76
THGGTYRCFGSFRHS

KIR3DL1

286

P43629
ASSGATGRVRHRGYS

PDE4D

96

Q08499
SGHFGSGERARSYAA

HOXA5

61

P20719
SRGRHGSDFGHSSSY

HRNR

661

Q86YZ3
GRTALFHHSGGSSGY

KIF26A

1646

Q9ULI4
FHHSGGSSGYESLRR

KIF26A

1651

Q9ULI4
GSLLHGHRYSSGSRS

IQSEC3

1166

Q9UPP2
SAGAGSGEFHVYRHL

PRKRIP1

71

Q9H875
THGGTYRCFGSFRDS

KIR2DS5

191

Q14953
DHSHVFSFGGYTLRG

ALPI

376

P09923
DSSEDGHYFRGHLGT

PAPPA2

411

Q9BXP8
IYVSGGFDGSRRHTS

KLHL12

381

Q53G59
GRAIRYHTGSLAFGS

SLC44A5

506

Q8NCS7
SGIHVSGRGFLASYS

DCBLD2

171

Q96PD2
LDEAGRGHSFSFHGA

H6PD

51

O95479
EAGLHSSARYGSHDG

JARID2

1101

Q92833
THGGTYRCFGSFRDS

KIR2DS1

191

Q14954
YRGYGSHTANRSHGG

NRK

1016

Q7Z2Y5
SHVSGHRSYYLRGAG

SARS2

221

Q9NP81
YTHGLNRTGFYRHSG

MYCT1

116

Q8N699
THGGTYRCFGSFRHS

KIR3DS1

286

Q14943
RSIYHSEGHRGLFSG

SLC25A38

166

Q96DW6
RHSGGGSRDGHRYSR

CLASRP

441

Q8N2M8
SGGHDSSSRSHRYGG

RBMXL3

761

Q8N7X1
SSSRSHRYGGGGRYE

RBMXL3

766

Q8N7X1
SNSYDRSHRYGGGGH

RBMXL3

846

Q8N7X1
FSHDLVSGRYRGSVH

UBE2O

61

Q9C0C9
LGASRHDGAYSDGHF

TENM4

271

Q6N022
GSYHCRARDGHSASG

SIGLEC1

571

Q9BZZ2
RKAGGGSYHHSSAFR

SKOR2

611

Q2VWA4
HTGTADGGHYYSFIR

USP34

2156

Q70CQ2
FDSSGGNGHALEHYR

USP13

236

Q92995
SYASHSGHRRTVGEG

USP54

1646

Q70EL1
RRAHGGFTNESSYHR

N4BP2L1

221

Q5TBK1
GFTNESSYHRRGGCH

N4BP2L1

226

Q5TBK1