Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	growth factor receptor binding	DAB2IP IL36A GATA3 GDNF CEACAM1 GLMN KL	5.79e-05	173	113	7	GO:0070851
GeneOntologyMolecularFunction	beta-glucuronidase activity	KL GUSB	1.89e-04	4	113	2	GO:0004566
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class I	PDIA3 LNPEP ULBP2 RAET1L TAP2	2.77e-06	41	112	5	GO:0002474
GeneOntologyBiologicalProcess	T cell mediated cytotoxicity	CEACAM1 ULBP2 EBAG9 RAET1L TAP2	3.94e-05	70	112	5	GO:0001913
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen	PDIA3 LNPEP ULBP2 RAET1L TAP2	5.87e-05	76	112	5	GO:0048002
GeneOntologyBiologicalProcess	negative regulation of endothelial cell apoptotic process	PDPK1 GATA3 FGB FGG	6.48e-05	40	112	4	GO:2000352
GeneOntologyBiologicalProcess	glial cell-derived neurotrophic factor receptor signaling pathway	GDF15 GATA3 GDNF	6.76e-05	15	112	3	GO:0035860
GeneOntologyBiologicalProcess	endothelial cell apoptotic process	DAB2IP PDPK1 GATA3 FGB FGG	7.06e-05	79	112	5	GO:0072577
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	ULBP2 RAET1L TAP2	1.00e-04	17	112	3	GO:0002484
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	ULBP2 RAET1L TAP2	1.00e-04	17	112	3	GO:0002476
GeneOntologyBiologicalProcess	antigen processing and presentation	PDIA3 LNPEP IGHG2 ULBP2 RAET1L TAP2	1.12e-04	139	112	6	GO:0019882
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class Ib	ULBP2 RAET1L TAP2	1.20e-04	18	112	3	GO:0002428
GeneOntologyBiologicalProcess	positive regulation of ureteric bud formation	GATA3 GDNF	1.74e-04	4	112	2	GO:0072107
GeneOntologyBiologicalProcess	regulation of ureteric bud formation	GATA3 GDNF	1.74e-04	4	112	2	GO:0072106
GeneOntologyBiologicalProcess	defense response to symbiont	DAB2IP SMARCA5 IL36A PDPK1 RTN4 GATA3 GATA6 CASP8 CEACAM1 USP44 SMPDL3B IGHG2 FGB ULBP2 RAET1L FGG TAP2 EIF4E2	1.90e-04	1286	112	18	GO:0140546
GeneOntologyBiologicalProcess	defense response to other organism	DAB2IP SMARCA5 IL36A PDPK1 RTN4 GATA3 GATA6 CASP8 EPX CEACAM1 USP44 SMPDL3B IGHG2 FGB ULBP2 RAET1L FGG TAP2 EIF4E2	1.96e-04	1407	112	19	GO:0098542
GeneOntologyBiologicalProcess	regulation of T cell mediated cytotoxicity	CEACAM1 ULBP2 RAET1L TAP2	1.97e-04	53	112	4	GO:0001914
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I	ULBP2 RAET1L TAP2	2.55e-04	23	112	3	GO:0019885
GeneOntologyBiologicalProcess	pore complex assembly	AHCTF1 RTN4 AFDN	2.55e-04	23	112	3	GO:0046931
GeneOntologyBiologicalProcess	T cell mediated immunity	GATA3 CEACAM1 ULBP2 EBAG9 RAET1L TAP2	2.66e-04	163	112	6	GO:0002456
GeneOntologyBiologicalProcess	innate immune response	DAB2IP SMARCA5 IL36A PDPK1 RTN4 GATA3 CASP8 CEACAM1 USP44 SMPDL3B FGB ULBP2 RAET1L FGG TAP2 EIF4E2	2.70e-04	1092	112	16	GO:0045087
GeneOntologyBiologicalProcess	neuropeptide catabolic process	LNPEP MME	2.89e-04	5	112	2	GO:0010813
GeneOntologyBiologicalProcess	regulation of mesonephros development	GATA3 GDNF	2.89e-04	5	112	2	GO:0061217
GeneOntologyBiologicalProcess	cytosol to endoplasmic reticulum transport	TMEM94 TAP2	2.89e-04	5	112	2	GO:0046967
GeneOntologyBiologicalProcess	postsynapse organization	RTN4 SH3GL2 SORBS1 GDNF PRICKLE2 AFDN POTEJ AGRN	3.12e-04	313	112	8	GO:0099173
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen	ULBP2 RAET1L TAP2	3.29e-04	25	112	3	GO:0002483
GeneOntologyBiologicalProcess	antigen processing and presentation via MHC class Ib	ULBP2 RAET1L TAP2	3.29e-04	25	112	3	GO:0002475
GeneOntologyBiologicalProcess	positive regulation of cytokine production	IL36A RTN4 FERMT1 GATA3 CASP8 EPX GLMN ULBP2 RAET1L TNFSF15 CD276	3.48e-04	586	112	11	GO:0001819
GeneOntologyBiologicalProcess	regulation of T cell mediated immunity	GATA3 CEACAM1 ULBP2 RAET1L TAP2	3.50e-04	111	112	5	GO:0002709
GeneOntologyBiologicalProcess	regulation of immune effector process	PDPK1 RTN4 GATA3 EPX CEACAM1 IGHG2 PKP3 ULBP2 RAET1L TAP2	3.80e-04	497	112	10	GO:0002697
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	DAB2IP CILP GDF15 PDPK1 FERMT1 GATA3 GATA6 GDF3 DKK3	4.16e-04	412	112	9	GO:0090287
GeneOntologyCellularComponent	TAP complex	PDIA3 TAP2	8.81e-05	3	114	2	GO:0042825
GeneOntologyCellularComponent	nuclear membrane	VAPA RGPD4 SPAG4 AHCTF1 GATA6 SULT1E1 NUP210 PRICKLE2 WDFY3	1.27e-04	349	114	9	GO:0031965
GeneOntologyCellularComponent	axoneme	RPGRIP1 DYNLT2B RSPH6A DNAL1 CFAP206 DNAH6 HYDIN	1.42e-04	207	114	7	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	RPGRIP1 DYNLT2B RSPH6A DNAL1 CFAP206 DNAH6 HYDIN	1.46e-04	208	114	7	GO:0097014
GeneOntologyCellularComponent	dynein complex	DYNLT2B DNAL1 DNAH6 DYNC1H1	2.15e-04	54	114	4	GO:0030286
GeneOntologyCellularComponent	nuclear envelope	VAPA RGPD4 SPAG4 AHCTF1 RTN4 GATA6 SULT1E1 NUP210 PRICKLE2 WDFY3 DYNC1H1	2.47e-04	560	114	11	GO:0005635
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	RPGRIP1 DYNLT2B RSPH6A DNAL1 CFAP206 DNAH6 HYDIN DYNC1H1	3.50e-04	317	114	8	GO:0032838
GeneOntologyCellularComponent	transferase complex	RGPD4 ERH RNF19A TBC1D5 METTL14 CEACAM1 KANSL3 PHKB GLMN PHF20L1 PRMT5 WDFY3 POTEJ SYVN1	7.58e-04	963	114	14	GO:1990234
GeneOntologyCellularComponent	cytoplasmic region	RPGRIP1 DYNLT2B RSPH6A DNAL1 CFAP206 DNAH6 HYDIN DYNC1H1	8.08e-04	360	114	8	GO:0099568
GeneOntologyCellularComponent	fibrinogen complex	FGB FGG	8.08e-04	8	114	2	GO:0005577
GeneOntologyCellularComponent	cell surface	DPP6 DUOX2 PDIA3 CEACAM1 KCNC4 LNPEP IGHG2 FGB ULBP2 RAET1L MME FGG SLC4A4 AGRN CD276	1.04e-03	1111	114	15	GO:0009986
Domain	Fib_alpha	FGB FGG	1.14e-04	3	116	2	SM01212
Domain	Fib_alpha	FGB FGG	1.14e-04	3	116	2	PF08702
Domain	Fibrinogen_a/b/g_coil_dom	FGB FGG	1.14e-04	3	116	2	IPR012290
Domain	Na/HCO3_transpt	SLC4A4 SLC4A9	3.78e-04	5	116	2	IPR003024
Domain	FIBRINOGEN_C_1	CNTNAP5 FGB FGG	1.02e-03	32	116	3	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP5 FGB FGG	1.02e-03	32	116	3	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP5 FGB FGG	1.02e-03	32	116	3	PS51406
Domain	-	VAPA HYDIN	1.04e-03	8	116	2	2.60.40.360
Domain	-	SLC4A4 SLC4A9	1.34e-03	9	116	2	3.40.1100.10
Domain	PapD-like	VAPA HYDIN	1.34e-03	9	116	2	IPR008962
Domain	Band3_cytoplasmic_dom	SLC4A4 SLC4A9	1.34e-03	9	116	2	IPR013769
Domain	Band_3_cyto	SLC4A4 SLC4A9	1.34e-03	9	116	2	PF07565
Domain	TGF-b_C	GDF15 GDF3 GDNF	1.56e-03	37	116	3	IPR001839
Domain	TGF_BETA_1	GDF15 GDF3 GDNF	1.56e-03	37	116	3	PS00250
Domain	TGFB	GDF15 GDF3 GDNF	1.56e-03	37	116	3	SM00204
Domain	TGF_BETA_2	GDF15 GDF3 GDNF	1.56e-03	37	116	3	PS51362
Domain	TGF_beta	GDF15 GDF3 GDNF	1.56e-03	37	116	3	PF00019
Domain	An_peroxidase	DUOX2 EPX	1.67e-03	10	116	2	PF03098
Domain	Haem_peroxidase_animal	DUOX2 EPX	1.67e-03	10	116	2	IPR019791
Domain	PTrfase/Anion_transptr	SLC4A4 SLC4A9	1.67e-03	10	116	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A4 SLC4A9	1.67e-03	10	116	2	IPR003020
Domain	HCO3_cotransp	SLC4A4 SLC4A9	1.67e-03	10	116	2	PF00955
Domain	Haem_peroxidase	DUOX2 EPX	1.67e-03	10	116	2	IPR010255
Domain	HCO3_transpt_C	SLC4A4 SLC4A9	1.67e-03	10	116	2	IPR011531
Domain	PEROXIDASE_3	DUOX2 EPX	1.67e-03	10	116	2	PS50292
Domain	-	DUOX2 EPX	1.67e-03	10	116	2	1.10.640.10
Domain	ZnF_GATA	GATA3 GATA6	2.42e-03	12	116	2	SM00401
Domain	ZF_PHD_1	ASXL1 TCF20 KDM4C PHF20L1	3.02e-03	96	116	4	PS01359
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DYNC1H1	3.31e-03	14	116	2	IPR024317
Domain	Dynein_HC_stalk	DNAH6 DYNC1H1	3.31e-03	14	116	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DYNC1H1	3.31e-03	14	116	2	IPR013602
Domain	DHC_N2	DNAH6 DYNC1H1	3.31e-03	14	116	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH6 DYNC1H1	3.31e-03	14	116	2	IPR011704
Domain	SEA	MUC3B AGRN	3.31e-03	14	116	2	SM00200
Domain	MT	DNAH6 DYNC1H1	3.31e-03	14	116	2	PF12777
Domain	AAA_8	DNAH6 DYNC1H1	3.31e-03	14	116	2	PF12780
Domain	AAA_5	DNAH6 DYNC1H1	3.31e-03	14	116	2	PF07728
Domain	TBC	TBC1D5 TBC1D9 TBC1D4	3.49e-03	49	116	3	SM00164
Domain	DHC_fam	DNAH6 DYNC1H1	3.81e-03	15	116	2	IPR026983
Domain	Dynein_heavy	DNAH6 DYNC1H1	3.81e-03	15	116	2	PF03028
Domain	Znf_GATA	GATA3 GATA6	3.81e-03	15	116	2	IPR000679
Domain	GATA	GATA3 GATA6	3.81e-03	15	116	2	PF00320
Domain	Dynein_heavy_dom	DNAH6 DYNC1H1	3.81e-03	15	116	2	IPR004273
Domain	GATA_ZN_FINGER_1	GATA3 GATA6	4.34e-03	16	116	2	PS00344
Domain	GATA_ZN_FINGER_2	GATA3 GATA6	4.34e-03	16	116	2	PS50114
Domain	RabGAP-TBC	TBC1D5 TBC1D9 TBC1D4	4.36e-03	53	116	3	PF00566
Domain	Rab-GTPase-TBC_dom	TBC1D5 TBC1D9 TBC1D4	4.84e-03	55	116	3	IPR000195
Domain	TBC_RABGAP	TBC1D5 TBC1D9 TBC1D4	4.84e-03	55	116	3	PS50086
Domain	Fibrinogen_CS	FGB FGG	6.10e-03	19	116	2	IPR020837
Domain	IG_MHC	IGHG2 ULBP2 RAET1L	6.18e-03	60	116	3	PS00290
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DAB2IP RGPD4 TCF20 ERH TBC1D5 SIPA1L3 SH3GL2 APC2 SORBS1 LETM1 CNTNAP5 ZBTB21 IQSEC1 AFDN WDFY3 SLC4A4 AGRN DYNC1H1 CAP2	5.72e-10	963	117	19	28671696
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	VAPA USP34 TCF20 TBC1D5 AHCTF1 RTN4 GATA3 PDIA3 CREB5 LETM1 TBC1D4 NUP210 IQSEC1 AFDN SYVN1 TAP2 SLX4 CD276	1.16e-07	1203	117	18	29180619
Pubmed	Stepwise assembly of fibrinogen is assisted by the endoplasmic reticulum lectin-chaperone system in HepG2 cells.	PDIA3 FGB FGG	1.48e-07	4	117	3	24040290
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DYNLT2B ERH TBC1D5 SIPA1L3 SH3GL2 CASP8 SORBS1 PHKB GLMN PRMT5 AFDN AGRN DYNC1H1 EIF4E2 FTSJ3	1.92e-07	853	117	15	28718761
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	VAPA RGPD4 ASXL1 ERH AHCTF1 SIPA1L3 GATM COPS2 PDIA3 KANSL3 PHKB PHF20L1 PRMT5 FGB SNU13 SLX4 DYNC1H1	3.40e-07	1155	117	17	20360068
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	CILP GDF15 GATM EPX CEACAM1 KL SMPDL3B IGHG2 GUSB FGB MME FGG POTEJ AGRN DYNC1H1 DOP1B	6.33e-07	1070	117	16	23533145
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DAB2IP ASXL1 TCF20 TMEM94 SORBS1 KLHL29 CHD6 SYVN1 DYNC1H1 DOP1B	1.27e-06	407	117	10	12693553
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	IL36A GDF15 APC2 GATA3 EPX GDF3 GDNF NFATC2 FGB ULBP2 RAET1L FGG TNFSF15	4.34e-06	824	117	13	20237496
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 KDM4C SIPA1L3 APC2 GATM SORBS1 ADD3 MTIF2 AFDN CHD6 WDFY3 SLX4 DKK3 DYNC1H1 CAP2 DOP1B	6.63e-06	1285	117	16	35914814
Pubmed	Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model.	VAPA ERH TBC1D5 PDIA3 USP44 SNU13	6.72e-06	135	117	6	31405213
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	VAPA RGPD4 RPGRIP1 SMARCA5 SIPA1L3 DUOX2 PLA2G4D EPX PDIA3 LETM1 PHF20L1 ZBTB21 ANKRD30A SNU13 CHD6 POTEJ DNAH6	6.82e-06	1442	117	17	35575683
Pubmed	Fibrinogen C-terminal peptidic sequences (Haptides) modulate fibrin polymerization.	FGB FGG	1.12e-05	2	117	2	14691567
Pubmed	Induction of fibrinogen biosynthesis and secretion from cultured pulmonary epithelial cells.	FGB FGG	1.12e-05	2	117	2	9028318
Pubmed	Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype.	FGB FGG	1.12e-05	2	117	2	32610551
Pubmed	Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cells.	SORBS1 AFDN	1.12e-05	2	117	2	10583506
Pubmed	A novel role for the fibrinogen Asn-Gly-Arg (NGR) motif in platelet function.	FGB FGG	1.12e-05	2	117	2	25413489
Pubmed	Renoprotection by GDF15 and Klotho: birds of a feather flock together.	GDF15 KL	1.12e-05	2	117	2	35597591
Pubmed	The Role of RCAS1 and oxytocinase in immune tolerance during pregnancy.	LNPEP EBAG9	1.12e-05	2	117	2	16113565
Pubmed	METTL14 promotes glomerular endothelial cell injury and diabetic nephropathy via m6A modification of α-klotho.	METTL14 KL	1.12e-05	2	117	2	34503454
Pubmed	Fibrinogen Tolaga Bay: a novel gammaAla341Val mutation causing hypofibrinogenaemia.	FGB FGG	1.12e-05	2	117	2	18000621
Pubmed	Covalent structure of fibrinogen.	FGB FGG	1.12e-05	2	117	2	6575689
Pubmed	Interaction of the Akt substrate, AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase.	TBC1D4 LNPEP	1.12e-05	2	117	2	16762977
Pubmed	Molecular characterization of 7 patients affected by dys- or hypo-dysfibrinogenemia: Identification of a novel mutation in the fibrinogen Bbeta chain causing a gain of glycosylation.	FGB FGG	1.12e-05	2	117	2	26006300
Pubmed	Preferential expression of NY-BR-1 and GATA-3 in male breast cancer.	GATA3 ANKRD30A	1.12e-05	2	117	2	29116378
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DAB2IP USP34 ASXL1 SIPA1L3 CHD6 WDFY3 DOP1B	1.17e-05	225	117	7	12168954
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TBC1D5 SIPA1L3 SORBS1 LETM1 GLMN TBC1D4 GFOD1 AFDN EIF4E2	2.11e-05	446	117	9	24255178
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DAB2IP PDPK1 RTN4 SORBS1 KL PRICKLE2 IQSEC1 CAP2	2.40e-05	347	117	8	17114649
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DPP6 RTN4 SIPA1L3 SORBS1 PDIA3 LETM1 ADD3 PHKB PRMT5 PRICKLE2 IQSEC1 AFDN FGG SLC4A4 DNAH6 DYNC1H1	2.49e-05	1431	117	16	37142655
Pubmed	Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion.	FGB FGG	3.36e-05	3	117	2	32126779
Pubmed	Genetic and environmental determinants of fibrin structure and function: relevance to clinical disease.	FGB FGG	3.36e-05	3	117	2	15217804
Pubmed	Regulation of gamma-fibrinogen chain expression by heterogeneous nuclear ribonucleoprotein A1.	FGB FGG	3.36e-05	3	117	2	15671034
Pubmed	Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism.	GATA3 NFATC2	3.36e-05	3	117	2	29969451
Pubmed	Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels.	FGB FGG	3.36e-05	3	117	2	16144795
Pubmed	Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.	FGB FGG	3.36e-05	3	117	2	19190816
Pubmed	Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders.	FGB FGG	3.36e-05	3	117	2	32877852
Pubmed	GATA3 siRNA inhibits the binding of NFAT1 to interleukin-13 promoter in human T cells.	GATA3 NFATC2	3.36e-05	3	117	2	20368097
Pubmed	Two-peaked synchronization in day/night expression rhythms of the fibrinogen gene cluster in the mouse liver.	FGB FGG	3.36e-05	3	117	2	12750384
Pubmed	The role of betagamma and alphagamma complexes in the assembly of human fibrinogen.	FGB FGG	3.36e-05	3	117	2	8910396
Pubmed	Clinical and biological features of 3 cases of hypofibrinogenemia associated with three different mutations (gamma Ala341Thr, Bbeta Tyr326Cys and Aalpha Asp496Asn).	FGB FGG	3.36e-05	3	117	2	17849064
Pubmed	Fibrinogen gene variation and ischemic stroke.	FGB FGG	3.36e-05	3	117	2	18331453
Pubmed	Fibrinogen, COPD and mortality in a nationally representative U.S. cohort.	FGB FGG	3.36e-05	3	117	2	22489912
Pubmed	HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.	METTL14 SYVN1	3.36e-05	3	117	2	34847358
Pubmed	Fibrinogen and fibrin.	FGB FGG	3.36e-05	3	117	2	6383194
Pubmed	Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction.	FGB FGG	3.36e-05	3	117	2	15735812
Pubmed	gammaAla82Gly represents a common fibrinogen gamma-chain variant in Caucasians.	FGB FGG	3.36e-05	3	117	2	15795540
Pubmed	Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.	TBC1D4 LNPEP	3.36e-05	3	117	2	30257216
Pubmed	New insights into fibrin (ogen) structure and function.	FGB FGG	3.36e-05	3	117	2	12617173
Pubmed	gamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptors.	FGB FGG	3.36e-05	3	117	2	6281794
Pubmed	Elevated plasma fibrinogen gamma' concentration is associated with myocardial infarction: effects of variation in fibrinogen genes and environmental factors.	FGB FGG	3.36e-05	3	117	2	17263791
Pubmed	Fibrinogen beta variants confer protection against coronary artery disease in a Greek case-control study.	FGB FGG	3.36e-05	3	117	2	20167083
Pubmed	Fibrinogen genes and myocardial infarction: a haplotype analysis.	FGB FGG	3.36e-05	3	117	2	18202324
Pubmed	A central role for intermolecular dityrosine cross-linking of fibrinogen in high molecular weight advanced oxidation protein product (AOPP) formation.	FGB FGG	3.36e-05	3	117	2	25280629
Pubmed	Fibrinogen and fragment D-induced vascular constriction.	FGB FGG	3.36e-05	3	117	2	15739255
Pubmed	Fibrinogen-induced endothelin-1 production from endothelial cells.	FGB FGG	3.36e-05	3	117	2	19193866
Pubmed	Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences.	FGB FGG	3.36e-05	3	117	2	7356959
Pubmed	The chymotrypsin-like protease complex of Treponema denticola ATCC 35405 mediates fibrinogen adherence and degradation.	FGB FGG	3.36e-05	3	117	2	17591786
Pubmed	Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study.	FGB FGG	3.36e-05	3	117	2	16706972
Pubmed	The fibrinogen gamma 10034C>T polymorphism is not associated with Peripheral Arterial Disease.	FGB FGG	3.36e-05	3	117	2	20709368
Pubmed	Clinical and molecular characterization by next generation sequencing of Spanish patients affected by congenital deficiencies of fibrinogen.	FGB FGG	3.36e-05	3	117	2	31295712
Pubmed	The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading.	FGB FGG	3.36e-05	3	117	2	24041635
Pubmed	Prognostic impact of CEA/CA19-9 at the time of recurrence in patients with gastric cancer.	GDF15 CEACAM1	3.36e-05	3	117	2	33682011
Pubmed	Preoperative Serum Fibrinogen is Associated With Acute Kidney Injury after Cardiac Valve Replacement Surgery.	FGB FGG	3.36e-05	3	117	2	32286477
Pubmed	Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway.	FGB FGG	3.36e-05	3	117	2	8100742
Pubmed	METTL14-Mediated m6A Modification of TUG1 Represses Ferroptosis in Alzheimer's Disease via Inhibiting GDF15 Ubiquitination.	GDF15 METTL14	3.36e-05	3	117	2	39206905
Pubmed	2.8 A crystal structures of recombinant fibrinogen fragment D with and without two peptide ligands: GHRP binding to the "b" site disrupts its nearby calcium-binding site.	FGB FGG	3.36e-05	3	117	2	12356313
Pubmed	CD276 and the gene signature composed of GATA3 and LGALS3 enable prognosis prediction of glioblastoma multiforme.	GATA3 CD276	3.36e-05	3	117	2	31075138
Pubmed	Fibrinogen Magdeburg I: a novel variant of human fibrinogen with an amino acid exchange in the fibrinopeptide A (Aalpha 9, Leu-->Pro).	FGB FGG	3.36e-05	3	117	2	12706644
Pubmed	Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions.	SORBS1 AFDN	3.36e-05	3	117	2	10085297
Pubmed	[Genetic analysis of a Chinese pedigree affected with Congenital dysfibrinogenemia due to variant of FGG gene].	FGB FGG	3.36e-05	3	117	2	37906135
Pubmed	Clinical phenotype, laboratory features and genotype of 35 patients with heritable dysfibrinogenaemia.	FGB FGG	3.36e-05	3	117	2	23061815
Pubmed	Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.	FGB FGG	3.36e-05	3	117	2	10074346
Pubmed	Crystal structure of fragment double-D from human fibrin with two different bound ligands.	FGB FGG	3.36e-05	3	117	2	9628725
Pubmed	Local chromatin interactions contribute to expression of the fibrinogen gene cluster.	FGB FGG	3.36e-05	3	117	2	30039577
Pubmed	A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1.	CASP8 TNFSF15	3.36e-05	3	117	2	25197060
Pubmed	Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini.	FGB FGG	3.36e-05	3	117	2	17688324
Pubmed	Congenital hypodysfibrinogenemia associated with a novel deletion of three residues (γAla289_Asp291del) in fibrinogen.	FGB FGG	3.36e-05	3	117	2	29748775
Pubmed	Preoperative peripheral plasma fibrinogen level is an independent prognostic marker in penile cancer.	FGB FGG	3.36e-05	3	117	2	27738342
Pubmed	The fibrinogen Aalpha R16C mutation results in fibrinolytic resistance.	FGB FGG	3.36e-05	3	117	2	16846481
Pubmed	Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.	ULBP2 RAET1L	3.36e-05	3	117	2	25212604
Pubmed	Association of fibrinogen with severity of stable coronary artery disease in patients with type 2 diabetic mellitus.	FGB FGG	3.36e-05	3	117	2	24803720
Pubmed	Congenital hypofibrinogenemia associated with novel homozygous fibrinogen Aα and heterozygous Bβ chain mutations.	FGB FGG	3.36e-05	3	117	2	25981141
Pubmed	Common genetic polymorphisms and haplotypes of fibrinogen alpha, beta, and gamma chains affect fibrinogen levels and the response to proinflammatory stimulation in myocardial infarction survivors: the AIRGENE study.	FGB FGG	3.36e-05	3	117	2	18772067
Pubmed	Quantitative studies on the release of platelet fibrinogen by thrombin.	FGB FGG	3.36e-05	3	117	2	5084810
Pubmed	Congenital hypofibrinogenemia: characterization of two missense mutations affecting fibrinogen assembly and secretion.	FGB FGG	3.36e-05	3	117	2	18676163
Pubmed	Fibrinogen as a Pleiotropic Protein Causing Human Diseases: The Mutational Burden of Aα, Bβ, and γ Chains.	FGB FGG	3.36e-05	3	117	2	29240685
Pubmed	Fibrinogen gene regulation.	FGB FGG	3.36e-05	3	117	2	22836683
Pubmed	Partial mRNA sequences for human A alpha, B beta, and gamma fibrinogen chains: evolutionary and functional implications.	FGB FGG	3.36e-05	3	117	2	6575389
Pubmed	MGMT, GATA6, CD81, DR4, and CASP8 gene promoter methylation in glioblastoma.	GATA6 CASP8	3.36e-05	3	117	2	22672670
Pubmed	Protein arginine methyltransferase 5 (PRMT5) activates WNT/β-catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3.	PRMT5 DKK3	3.36e-05	3	117	2	33462997
Pubmed	Polymerization of fibrin: Direct observation and quantification of individual B:b knob-hole interactions.	FGB FGG	3.36e-05	3	117	2	16940416
Pubmed	Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.	FGB FGG	3.36e-05	3	117	2	9333233
Pubmed	The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients.	GDF15 SLC25A37	3.36e-05	3	117	2	30761871
Pubmed	Fibrinogen.	FGB FGG	3.36e-05	3	117	2	10467729
Pubmed	Fibrin drives thromboinflammation and neuropathology in COVID-19.	FGB FGG	3.36e-05	3	117	2	39198643
Pubmed	Congenital fibrinogen disorders: an update.	FGB FGG	3.36e-05	3	117	2	23852822
Pubmed	Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study.	FGB FGG	3.36e-05	3	117	2	18278190
Pubmed	Haplotypes of the fibrinogen gene and cerebral small vessel disease: the Rotterdam scan study.	FGB FGG	3.36e-05	3	117	2	17951283
Pubmed	Disulfide bridges in nh2 -terminal part of human fibrinogen.	FGB FGG	3.36e-05	3	117	2	936108
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TCF20 TBC1D5 SIPA1L3 SORBS1 TBC1D4 PRMT5 ZBTB21 IQSEC1 AFDN CRYBG3 DOP1B EIF4E2	3.49e-05	861	117	12	36931259
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RGPD4 SMARCA5 AHCTF1 GATA3 ADD3 NFATC2 DYNC1H1 FTSJ3	3.79e-05	370	117	8	22922362
Cytoband	4q28	FGB FGG	2.29e-04	9	117	2	4q28
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 CNTNAP5 TBC1D4 PCNX4 CCDC68 ANKRD30A CRYBG3 SLC4A9	2.58e-08	181	116	8	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 GATM SULT1E1 SMPDL3B FGB FGG	8.35e-07	196	116	7	4deaadb9796b907b7480fb7af5ed76ebad240850
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 GATM SULT1E1 SMPDL3B FGB FGG	8.64e-07	197	116	7	f097e729f515e7945b9482e9f9dbc9536b90f0bb
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 SULT1E1 PKP3 FGB FGG TNFSF15	9.24e-07	199	116	7	7540973d36f78cd9f13210635ff0708d20c8b209
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 SULT1E1 PKP3 FGB FGG TNFSF15	9.24e-07	199	116	7	416ea20b49a48bf47ec3abfbe707e4d1254e2f88
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 GATA6 ADD3 SULT1E1 PKP3 FGB FGG	9.24e-07	199	116	7	9d24223b571fba202455c5bd49bd79530abf09c0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 FERMT1 GATA6 SMPDL3B PKP3 FGB FGG	9.56e-07	200	116	7	eef5f6bd9ff5d985def8befcf45786234317f144
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 FERMT1 GATA6 SMPDL3B PKP3 FGB FGG	9.56e-07	200	116	7	4b1ae9f71f0fe998b06fa580885572d1fc1544e2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 TBC1D4 CCDC68 ANKRD30A SLC4A9 DOP1B	7.77e-06	180	116	6	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPGRIP1 PLA2G4D ADD3 CEACAM1 AFDN DKK3	8.54e-06	183	116	6	a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPGRIP1 PLA2G4D ADD3 CEACAM1 AFDN DKK3	8.54e-06	183	116	6	13ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DPP6 TCF20 SIPA1L3 GATA3 PRICKLE2 HYDIN	9.96e-06	188	116	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 GATA3 KLHL29 PKP3 MME DKK3	1.03e-05	189	116	6	6f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 GATA3 KLHL29 PKP3 MME DKK3	1.03e-05	189	116	6	3b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 GATA3 KLHL29 PKP3 MME DKK3	1.03e-05	189	116	6	38acb307907fde68b992057714448c1561d69ee3
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GATA3 GATA6 FOXB1 SMPDL3B GFOD1 SLC4A4	1.06e-05	190	116	6	251d50a77e5118a9ad19ea01a7c7c862230ed63c
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GATM SORBS1 GDNF CREB5 KCNC4 CAP2	1.06e-05	190	116	6	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 CILP GAS2 ADD3 PRELP MME	1.12e-05	192	116	6	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 CREB5 KLHL29 NFATC2 FGB FGG	1.12e-05	192	116	6	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC60 DYNLT2B DUOX2 DNAL1 BEST4 HYDIN	1.23e-05	195	116	6	d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF15 CREB5 CEACAM1 USP44 PRICKLE2 CCDC68	1.23e-05	195	116	6	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	facs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF15 CREB5 CEACAM1 USP44 PRICKLE2 CCDC68	1.23e-05	195	116	6	7e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell	wk_20-22-Epithelial-Distal_epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SMARCA5 GDF15 SMPDL3B PKP3 AGRN TNFSF15	1.26e-05	196	116	6	cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCell	proximal-mesenchymal-Myofibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DPP6 GDNF CREB5 PRELP CCDC68 DKK3	1.30e-05	197	116	6	ab21baea931ff134cf5a7ee369c091230988108b
ToppCell	proximal-mesenchymal-Myofibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DPP6 GDNF CREB5 PRELP CCDC68 DKK3	1.30e-05	197	116	6	15f2f169758a07143fc7d1bdb58d0b4d750a0be4
ToppCell	proximal-3-mesenchymal-Myofibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DPP6 GDNF CREB5 PRELP CCDC68 DKK3	1.30e-05	197	116	6	c59b64674fb4aaa945c1df7e4a9a3605c7cd2b75
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 CILP GAS2 ADD3 PRELP DKK3	1.30e-05	197	116	6	cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DPP6 KDM4C TBC1D5 SIPA1L3 PRICKLE2 WDFY3	1.34e-05	198	116	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 GATM SULT1E1 PKP3 FGB	1.38e-05	199	116	6	fbd9d1a21a94a0c9e0081964c5a2e865c37f1975
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA6 GATM SULT1E1 PKP3 FGB FGG	1.38e-05	199	116	6	722b9ebf7e47c361a7f192689a8d46947ec62b45
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GATA6 GATM SULT1E1 PKP3 FGB FGG	1.38e-05	199	116	6	5f77d3892db7b0d657870ccd596e08a411928bfc
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 TBC1D9 CNTNAP5 KL PCNX4	2.98e-05	137	116	5	81cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 GLMN CNTNAP5 TBC1D4 NFATC2	3.41e-05	141	116	5	c7043f3b024bb16bbc89e33075f5b6ced5cb9185
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 GLMN NFATC2 NUP210 DKK3	6.42e-05	161	116	5	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 CCDC68 ANKRD30A SLC4A9 DOP1B	7.21e-05	165	116	5	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA3 SLC25A37 DNAH6 HYDIN	7.57e-05	86	116	4	1f44bb41835445aa60a2e3c31616c5847447a246
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	DYNLT2B DNAL1 PCNX4 CFAP206 DNAH6	7.63e-05	167	116	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TBC1D5 GATM SMPDL3B CYP2U1 AFDN	7.85e-05	168	116	5	d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBC1D5 GATM SMPDL3B CYP2U1 AFDN	8.07e-05	169	116	5	ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	APC2 TMIE CCDC68 CRYBG3 DSCC1	8.07e-05	169	116	5	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 GATA6 PKP3 FGB FGG	9.26e-05	174	116	5	e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDF15 GATA6 PKP3 FGB FGG	9.26e-05	174	116	5	ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SMARCA5 GDF15 PKP3 AGRN TNFSF15	9.26e-05	174	116	5	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP5 PCNX4 CCDC68 ANKRD30A SLC4A9	9.51e-05	175	116	5	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 PKP3 NUP210 FGG	9.51e-05	175	116	5	6759d200a133034756de9cdf2d5daceca927aac9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 PCNX4 ANKRD30A SLC4A9 DOP1B	9.77e-05	176	116	5	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATM USP44 FGB FGG	1.00e-04	177	116	5	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	droplet-Lung-nan-21m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 GATA3 FOXB1 TBC1D4 PKP3	1.00e-04	177	116	5	8cc74873f4d2d0f81042426a687b01750abc72d2
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 GATA3 FOXB1 TBC1D4 PKP3	1.00e-04	177	116	5	fe0f6a73264632bdd4f9fbc22de2d155ba2bcf8c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP5 TBC1D4 CCDC68 CRYBG3 SLC4A9	1.06e-04	179	116	5	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 FGB FGG TNFSF15	1.09e-04	180	116	5	8d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell	COPD-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	ASXL1 RNF19A GATA3 CASP8 TBC1D4	1.09e-04	180	116	5	51a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RNF19A FERMT1 GDNF KLHL29 CRYBG3	1.14e-04	182	116	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	droplet-Thymus-nan-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 TBC1D9 PRELP DNAH6 HYDIN	1.14e-04	182	116	5	f6717e97e87513384149800c9fd8dea821ab9393
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADD3 CEACAM1 TBC1D4 SNU13 AFDN	1.14e-04	182	116	5	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SPAG4 AFF2 KCNC4 IQSEC1 MME	1.14e-04	182	116	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ADD3 CEACAM1 TBC1D4 SNU13 AFDN	1.14e-04	182	116	5	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	droplet-Thymus-nan-18m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FERMT1 TBC1D9 PRELP DNAH6 HYDIN	1.14e-04	182	116	5	c33b0d532822186a1e8e645500347972468718c0
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 GATA6 GATM FGB FGG	1.17e-04	183	116	5	0d21befacefc6c597e7b501ed41b7fe9385a78df
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RPGRIP1 GDF15 PKP3 SNU13 RAET1L	1.23e-04	185	116	5	eb174c037e7defb015de35a30157eacf0385490a
ToppCell	COPD-Lymphoid-T_Regulatory\|COPD / Disease state, Lineage and Cell class	ASXL1 RNF19A GATA3 CASP8 TBC1D4	1.23e-04	185	116	5	846403edd4c8f646201d519055198fc38b7ffff9
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC60 DYNLT2B CFAP206 DNAH6 HYDIN	1.23e-04	185	116	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RPGRIP1 GDF15 PKP3 SNU13 RAET1L	1.23e-04	185	116	5	add23ccccfca9374a68f127108b9a6dfe4d8cd66
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma\|TCGA-Prostate / Sample_Type by Project: Shred V9	GDF15 LETM1 SMPDL3B PKP3 NUP210	1.23e-04	185	116	5	9d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GATA3 CASP8 TBC1D4 NFATC2 CHD6	1.27e-04	186	116	5	bbcd9062c0f6f65ca6f3cb101b6fa72ddd1e14fe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SIPA1L3 SH3GL2 KL MME SLC4A4	1.27e-04	186	116	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 CNTNAP5 PCNX4 ANKRD30A SLC4A9	1.30e-04	187	116	5	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GATA3 TBC1D9 CNTNAP5 SLC4A4 SLC4A9	1.33e-04	188	116	5	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tregs\|Lung / Manually curated celltypes from each tissue	ASXL1 RNF19A GATA3 CASP8 TBC1D4	1.33e-04	188	116	5	604f340052807bd902915eca942a97ccc36b42e0
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	RTN4 CEACAM1 KLHL29 ANKRD30A MME	1.33e-04	188	116	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL29 TBC1D4 WDFY3 DNAH6 HYDIN	1.36e-04	189	116	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNLT2B KLHL29 PRELP AFDN DKK3	1.36e-04	189	116	5	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CILP SH3GL2 GAS2 ADD3 FGB	1.40e-04	190	116	5	3aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 GAS2 CNTNAP5 PCNX4 SLC4A9	1.40e-04	190	116	5	bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SPAG4 TBC1D9 SMPDL3B IGHG2 SYVN1	1.40e-04	190	116	5	a21d0c574abf21e7cb865a21a48f29c92d055fbe
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	AFF2 GATM SULT1E1 KCNC4 CCDC68	1.40e-04	190	116	5	10125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 SMARCA5 CEACAM1 MTIF2 SLC4A4	1.43e-04	191	116	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	RNF19A AHCTF1 PDIA3 LNPEP DOP1B	1.43e-04	191	116	5	9454f642c3621370fa23640b631301346b300950
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AFF2 CREB5 KLHL29 PRICKLE2 HYDIN	1.43e-04	191	116	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	15-Airway-Epithelial-Secretory_progenitor\|Airway / Age, Tissue, Lineage and Cell class	GDF15 SMPDL3B PKP3 SLC4A4 TNFSF15	1.43e-04	191	116	5	9359d8c6b00f8977848986baf3c950157adf4c9a
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FERMT1 SULT1E1 PKP3 ANKRD30A FGG	1.43e-04	191	116	5	a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 SMARCA5 CEACAM1 MTIF2 SLC4A4	1.43e-04	191	116	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 SMARCA5 CEACAM1 MTIF2 SLC4A4	1.43e-04	191	116	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 CNTNAP5 TBC1D4 KCNC4 SLC4A9	1.47e-04	192	116	5	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ASXL1 SORBS1 CREB5 SULT1E1 ZBTB21	1.47e-04	192	116	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RTN4 SLC25A37 CEACAM1 MME WDFY3	1.50e-04	193	116	5	e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 SMARCA5 WDFY3 CRYBG3 DYNC1H1	1.50e-04	193	116	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	LA\|World / Chamber and Cluster_Paper	CILP RTN4 CREB5 KLHL29 PRICKLE2	1.50e-04	193	116	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CILP GATA6 SULT1E1 KLHL29 PRELP	1.50e-04	193	116	5	09de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCell	CF-Lymphoid\|CF / Disease state, Lineage and Cell class	ASXL1 GLMN NFATC2 IGHG2 NUP210	1.50e-04	193	116	5	11de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNLT2B DNAL1 BEST4 DNAH6 HYDIN	1.54e-04	194	116	5	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 GATA3 TBC1D9 KCNC4 DOP1B	1.54e-04	194	116	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP USP34 SMARCA5 SORBS1 NFATC2	1.54e-04	194	116	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 GATA3 TBC1D9 KCNC4 DOP1B	1.54e-04	194	116	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	PCW_05-06-Epithelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GDF15 SH3GL2 SMPDL3B PKP3 NUP210	1.54e-04	194	116	5	47a1369c22fcbfe00b08376eb610a61c355548db
ToppCell	COVID_vent-Myeloid-Monocytic-Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SLC25A37 CREB5 CEACAM1 MME WDFY3	1.54e-04	194	116	5	eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	GDF15 GATM CREB5 ADD3 CEACAM1	1.58e-04	195	116	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	GAS2 SORBS1 TBC1D4 SLC4A4 CAP2	1.58e-04	195	116	5	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF19A GATA3 CASP8 NFATC2 SLC4A4	1.58e-04	195	116	5	42382653e977714bff453bece26a6cd66ea2cc1f
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNLT2B GDF15 CFAP206 DNAH6 HYDIN	1.58e-04	195	116	5	0fbba312e9ba9b70b4b814b67b6eb1f6544aaf6d
Drug	celecoxib	IL36A GDF15 PDPK1 RTN4 APC2 CASP8 GDNF TBC1D9 AGRN TNFSF15	1.51e-06	273	117	10	CID000002662
Disease	level of UL16-binding protein 6 in blood serum	ULBP2 RAET1L	1.43e-05	2	112	2	OBA_2043185
Disease	Hereditary factor I deficiency disease	FGB FGG	4.27e-05	3	112	2	cv:C0019250
Disease	Familial dysfibrinogenemia	FGB FGG	4.27e-05	3	112	2	cv:C0272350
Disease	Congenital afibrinogenemia	FGB FGG	4.27e-05	3	112	2	cv:C2584774
Disease	AFIBRINOGENEMIA, CONGENITAL	FGB FGG	4.27e-05	3	112	2	202400
Disease	congenital afibrinogenemia (is_implicated_in)	FGB FGG	4.27e-05	3	112	2	DOID:2236 (is_implicated_in)
Disease	DYSFIBRINOGENEMIA, CONGENITAL	FGB FGG	4.27e-05	3	112	2	616004
Disease	Dysfibrinogenemia, Congenital	FGB FGG	4.27e-05	3	112	2	C0272350
Disease	Afibrinogenemia	FGB FGG	8.53e-05	4	112	2	C0001733
Disease	Congenital hypofibrinogenemia	FGB FGG	8.53e-05	4	112	2	C2584774
Disease	Fibrinogen Deficiency	FGB FGG	1.42e-04	5	112	2	C4316812
Disease	esophagus squamous cell carcinoma (is_marker_for)	DAB2IP KDM4C CASP8 TAP2	1.84e-04	74	112	4	DOID:3748 (is_marker_for)
Disease	Neoplasm of uncertain or unknown behavior of breast	PDPK1 GATA3 CASP8	5.11e-04	41	112	3	C0496956
Disease	Breast adenocarcinoma	PDPK1 GATA3 CASP8	5.11e-04	41	112	3	C0858252
Disease	pulmonary embolism (biomarker_via_orthology)	FGB FGG	9.19e-04	12	112	2	DOID:9477 (biomarker_via_orthology)
Disease	epithelial cell adhesion molecule measurement	USP34 RTN4 MTIF2	9.71e-04	51	112	3	EFO_0010574
Disease	anemia (implicated_via_orthology)	SLC4A4 SLC4A9	1.45e-03	15	112	2	DOID:2355 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	GDF15 GAS2 CREB5 NUP210 PRICKLE2 ULBP2 RAET1L	1.62e-03	447	112	7	EFO_0000694, MONDO_0100096
Disease	Global developmental delay	TCF20 TMEM94 APC2 IQSEC1	1.68e-03	133	112	4	C0557874
Disease	Charcot-Marie-Tooth disease type 2	MME DYNC1H1	1.87e-03	17	112	2	cv:C0270914
Disease	arterial stiffness measurement	DAB2IP TCF20 RSPH6A	1.87e-03	64	112	3	EFO_0004517
Disease	Tourette syndrome, schizophrenia	TCF20 TBC1D5	2.10e-03	18	112	2	EFO_0004895, MONDO_0005090
Disease	diet measurement, colorectal cancer	DPP6 GATA3	2.34e-03	19	112	2	EFO_0008111, MONDO_0005575
Disease	Prostatic Neoplasms	DAB2IP GDF15 PDIA3 SULT1E1 PKP3 CHD6 MME CD276	2.45e-03	616	112	8	C0033578
Disease	Malignant neoplasm of prostate	DAB2IP GDF15 PDIA3 SULT1E1 PKP3 CHD6 MME CD276	2.45e-03	616	112	8	C0376358
Disease	breast cancer (is_implicated_in)	KDM4C CASP8 SULT1E1 EBAG9	2.60e-03	150	112	4	DOID:1612 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	TCF20 CNTNAP5 CHD6 WDFY3	2.73e-03	152	112	4	DOID:0060041 (implicated_via_orthology)
Disease	Liver Cirrhosis, Experimental	TCF20 RTN4 TBC1D9 ADD3 SULT1E1 MME SLC4A4 TAP2 CD276	2.79e-03	774	112	9	C0023893
Disease	Headache, HbA1c measurement	RTN4 CASP8	2.86e-03	21	112	2	EFO_0004541, HP_0002315
Disease	kidney disease (biomarker_via_orthology)	GATM CASP8	2.86e-03	21	112	2	DOID:557 (biomarker_via_orthology)
Disease	non-small cell lung carcinoma	CASP8 COPS2 EIF4E2	2.95e-03	75	112	3	EFO_0003060
Disease	Lung Neoplasms	DAB2IP GATA6 CASP8 CEACAM1 IQSEC1	3.46e-03	265	112	5	C0024121
Disease	Malignant neoplasm of lung	DAB2IP GATA6 CASP8 CEACAM1 IQSEC1	3.51e-03	266	112	5	C0242379

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSVMLQPFDYDPNEK	VAPA	76	Q9P0L0
DSYPEPTQLLMGTKS	TNFSF15	186	O95150
SVDEMYQNLPPAEKD	BEST4	336	Q8NFU0
TLLTMDKYAPDDIPN	AFDN	851	P55196
DSELMYQPKAPEINI	SLC4A9	966	Q96Q91
TPLKQPVDYRDNTLM	AGBL3	156	Q8NEM8
PYKNDPEILAMTNLV	COPS2	301	P61201
AINSPLQSPYTDSMK	LINC00303	36	Q3SY05
AMLPAFESKTPQEYA	CRYBG3	1886	Q68DQ2
EDDTVPLSPLKYMAQ	ADD3	416	Q9UEY8
NAMERDPLEAKSPYT	AFF2	1111	P51816
QSPEALADMYQPRSL	FERMT1	226	Q9BQL6
QELFYTPEMADPKSE	AGRN	1146	O00468
MFPPESKQKDYEENS	ANKRD30A	551	Q9BXX3
LQVAAPYSKPSMTLE	CD276	136	Q5ZPR3
PPRDKMEDNSALYES	CCDC68	11	Q9H2F9
LENYSDAPMTPKQIL	ASXL1	21	Q8IXJ9
ESSSTKPDEEPLYMN	CCDC60	281	Q8IWA6
QVYPPKDTSTQSMRE	CFAP206	571	Q8IYR0
SLEQLEPDYFKDMTP	EBAG9	86	O00559
PEIEAEQILMSPNSY	NUP210	1291	Q8TEM1
FPSIKTDNMLSDQTP	CREB5	46	Q02930
MQKESQGYLSPESSP	CREB5	446	Q02930
MSPSLFNLLQEYPDD	DAB2IP	531	Q5VWQ8
DKSQPNMLFVEIPEY	NFATC2	631	Q13469
DENGKTIDEAYPSMP	MTIF2	401	P46199
TTAPKPTMADELYNQ	GATM	211	P50440
AKSNTPPMYLQADIE	METTL14	161	Q9HCE5
INSSIYAMKEIEPEP	SMPDL3B	71	Q92485
LSKVQMPPSYLDTES	DOP1B	536	Q9Y3R5
LLNTDMYSPNVKPER	IQSEC1	661	Q6DN90
EMELSPDSQITLYGP	KIAA1109	726	Q2LD37
MYLPDTLSPADQLKS	LETM1	421	O95202
PTPRLYTEALQEKMQ	DUOX2	1006	Q9NRD8
PTKLSPISMLYQDNN	GDF3	331	Q9NR23
KSSEMNILIPQDGDY	CAP2	436	P40123
TSEMYLIQPDSSVKP	FGB	251	P02675
MSPDVPLLNDYKQDF	PCNX4	1	Q63HM2
SASPMDLLSYFKQPV	EPX	66	P11678
KRMNPNSPSITYDIS	ERH	41	P84090
ATAKPEDRNDPMLLY	MME	286	P08473
LMPYHKPDSSNEEND	KDM4C	651	Q9H3R0
MTEADVNPKAYPLAD	SNU13	1	P55769
FLNMKPEIQPSDTSY	LNPEP	636	Q9UIQ6
ALSSDSNMPEDYPDQ	GDNF	46	P39905
PASYNPMVLIQKTDT	GDF15	276	Q99988
IQSSPEKMLPLSEIY	FOXB1	26	Q99853
SLKYTEDMTPTEQTP	PRICKLE2	526	Q7Z3G6
APSLTDKAQMPYTEA	CYP2U1	391	Q7Z449
QLTYNPDESSKPNMI	FGG	91	P02679
YQVPLPDSMKLESSH	GATA3	186	P23771
PEQPEEMYQTLAALS	GATA6	141	Q92908
MDITSLYNLKFQPPT	APC2	81	O95996
PEKVYTNDILAMLSP	DNAH6	1246	Q9C0G6
DIMDLYNQPEPVKSF	IL36A	91	Q9UHA7
TYFLEPNTMVLKPNE	HYDIN	2876	Q4G0P3
LLMENPYEGPDSQKE	DSCC1	141	Q9BVC3
PTYPLEGSELKSEDM	CHD6	2011	Q8TD26
SNDPPNKMNEVTYST	CEACAM1	481	P13688
QDPPLMFTEEYQKSL	GUSB	551	P08236
PLQPLMDNLESQTYE	PRMT5	311	O14744
EEQPYLEMDLSSPQT	CASP8	376	Q14790
LETVNDYNPLMKDFP	DYNC1H1	326	Q14204
ETVTSTPMPLYDNQK	KANSL3	81	Q9P2N6
DYPESMKNNLSSILP	KL	336	Q9UEF7
QVYTLPPSREEMTKN	IGHG2	226	P01859
PENNYKTTPPMLDSD	IGHG2	266	P01859
LDIMYSFPNKTDTPI	AHCTF1	781	Q8WYP5
YAQIPPIEKMDASLS	DNAL1	31	Q4LDG9
IDDYNLPMQILKPAT	DPP6	601	P42658
LPPNTIMEYKTHTDS	EIF4E2	206	O60573
PALSYPQEEATLNEM	DKK3	36	Q9UBP4
LANAEYSPEEMPQLT	DYNLT2B	56	Q8WW35
YSPEEMPQLTKHLSE	DYNLT2B	61	Q8WW35
MFQEPYPVTKNISLS	CNTNAP5	1011	Q8WYK1
EKQDDMTSFYNTPPL	PHKB	1046	Q93100
DYQLDSMPSQLTPKE	PLA2G4D	626	Q86XP0
YNETAPMLEQAISPK	PHF20L1	301	A8MW92
MPFSPQLESEYEQVK	MUC3B	1006	Q9H195
SKSPTLKDMNPDNYL	GAS2	286	O43903
LLPVPYSKEQIQMDD	GLMN	156	Q92990
SDYSEMAKVEQPVPD	RTN4	716	Q9NQC3
LDTLRDDPEMQPTYK	RSPH6A	256	Q9H0K4
NMNTLYPDATPEELQ	SYVN1	271	Q86TM6
PMEESSINYTFKTPE	RGPD4	1626	Q7Z3J3
TDSDDVIVPPMSQKY	RPGRIP1	1096	Q96KN7
NIAIMTEEPELSPAY	GFOD1	361	Q9NXC2
IAKMDATANDVPSPY	PDIA3	431	P30101
PKLTAYLPAMSEDDE	PDPK1	356	O15530
TRMQSLSPDPKAQYT	SLC25A37	71	Q9NYZ2
MPKYSSENSNPEQDL	POTEJ	446	P0CG39
EIMSPLYQDEAPKGT	FTSJ3	581	Q8IY81
PETYDMNTSEPKTEQ	SIPA1L3	1051	O60292
EKVFSYMDRQPNLPS	TAP2	441	Q03519
YMEKNQLEEVPSALP	PRELP	156	P51888
PLENEPKEMLTLSEY	SPAG4	191	Q9NPE6
SNEDLPISMENPYKE	MRPS18C	46	Q9Y3D5
MFPEKSPSIDLTQSN	SLX4	1116	Q8IY92
NDTSEYTMLAPLDPL	CILP	1056	O75339
LPSAVKYLMASDPNL	PKP3	321	Q9Y446
MDSQVPVYSPSIDLK	ZBTB21	346	Q9ULJ3
PPNTMTEKFSDLLQF	WDFY3	66	Q8IZQ1
LNSYIPLDKEGNSME	RNF19A	601	Q9NV58
MKNNPSTNYTTLPDE	SULT1E1	231	P49888
SKTQPGMESDPYEAE	TMEM94	531	Q12767
EYLQPNPASRAKLSM	SH3GL2	56	Q99962
MYTDKLETVPPLNEL	TMIE	101	Q8NEW7
TMKYKQTDPEHPDND	TKTL2	56	Q9H0I9
VKNPVDYMDLPFSSS	SORBS1	931	Q9BX66
YKMHVLPEPSSDQDE	TBC1D9	931	Q6ZT07
ENYTPKEPLTLQARM	RAET1L	111	Q5VY80
STAPEMKQINLTDYP	TCF20	826	Q9UGU0
YLIKAQPDDPESQMA	TBC1D4	141	O60343
IMEQQPFLSDSKPSD	SLC4A4	1051	Q9Y6R1
AQPSEEMKTVLNPEY	TBC1D5	231	Q92609
SPENSSVKEYRMEVP	USP34	3406	Q70CQ2
ENYTPKEPLTLQARM	ULBP2	111	Q9BZM5
PDPTYEEKMQTDRAN	SMARCA5	76	O60264
MELIQPKEPTSQYIS	USP44	366	Q9H0E7
IESPMIDNKYAPAVT	KLHL29	761	Q96CT2
QLESPMYCKSEETSP	KCNC4	501	Q03721