Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	STAT_TF_alpha	STAT3 RNF20	1.18e-04	8	39	2	IPR013800
Domain	Prefoldin	KIF21B KIF4A RNF20	4.54e-04	72	39	3	IPR009053
Domain	AT_hook	KMT2C BAZ2A	5.01e-04	16	39	2	PF02178
Domain	AT_hook	KMT2C BAZ2A	1.44e-03	27	39	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2C BAZ2A	1.44e-03	27	39	2	IPR017956
Domain	HMGI/Y_DNA-bd_CS	KMT2C BAZ2A	1.90e-03	31	39	2	IPR000637
Domain	Kinesin_motor_CS	KIF21B KIF4A	3.31e-03	41	39	2	IPR019821
Domain	Kinesin-like_fam	KIF21B KIF4A	3.63e-03	43	39	2	IPR027640
Domain	KINESIN_MOTOR_1	KIF21B KIF4A	3.80e-03	44	39	2	PS00411
Domain	-	KIF21B KIF4A	3.80e-03	44	39	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF21B KIF4A	3.80e-03	44	39	2	IPR001752
Domain	Kinesin	KIF21B KIF4A	3.80e-03	44	39	2	PF00225
Domain	KISc	KIF21B KIF4A	3.80e-03	44	39	2	SM00129
Domain	KINESIN_MOTOR_2	KIF21B KIF4A	3.80e-03	44	39	2	PS50067
Domain	ubiquitin	IKBKB SACS	4.33e-03	47	39	2	PF00240
Domain	DnaJ	DNAJC17 SACS	4.70e-03	49	39	2	SM00271
Domain	DNAJ_1	DNAJC17 SACS	4.70e-03	49	39	2	PS00636
Domain	DNAJ_2	DNAJC17 SACS	4.70e-03	49	39	2	PS50076
Domain	-	DNAJC17 SACS	4.70e-03	49	39	2	1.10.287.110
Domain	DnaJ_domain	DNAJC17 SACS	5.08e-03	51	39	2	IPR001623
Domain	Ubiquitin_dom	IKBKB SACS	6.52e-03	58	39	2	IPR000626
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KIF4A KMT2C CEP85 BAZ2A YAP1 RABEP1 PCM1 SPTAN1 STAT3 HAUS5 NUMA1	2.10e-11	549	40	11	38280479
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	NCOA1 KMT2C PSPC1 STAT3 NUMA1 RNF20	1.92e-07	220	40	6	35785414
Pubmed	Human transcription factor protein interaction networks.	NCOA1 KMT2C SMG5 CEP85 YAP1 STRBP PCM1 SPTAN1 STAT3 NUMA1 MITF	4.17e-07	1429	40	11	35140242
Pubmed	Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA1.	NCOA1 STAT3	1.29e-06	2	40	2	28579428
Pubmed	Co-activation of STAT3 and YES-Associated Protein 1 (YAP1) Pathway in EGFR-Mutant NSCLC.	YAP1 STAT3	1.29e-06	2	40	2	28376152
Pubmed	Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation.	IKBKB STAT3	1.29e-06	2	40	2	20227042
Pubmed	Region 752-761 of STAT3 is critical for SRC-1 recruitment and Ser727 phosphorylation.	NCOA1 STAT3	1.29e-06	2	40	2	15530426
Pubmed	YAP regulates intestinal epithelial cell proliferation through activation of STAT3 in DSS-induced colitis and associated cancer.	YAP1 STAT3	1.29e-06	2	40	2	36748373
Pubmed	YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells.	YAP1 STAT3	1.29e-06	2	40	2	30342005
Pubmed	STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression.	STAT3 MITF	1.29e-06	2	40	2	14737107
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	SCYL1 MAP7D2 DNAJC17 CEP85 PSPC1 YAP1 STRBP GOLGA2 PCM1	1.68e-06	1007	40	9	34597346
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SCYL1 RABEP1 GOLGA2 SPTAN1 NUMA1 RNF20	3.37e-06	360	40	6	33111431
Pubmed	IκB Kinase-β Regulates Neutrophil Recruitment Through Activation of STAT3 Signaling in the Esophagus.	IKBKB STAT3	3.87e-06	3	40	2	34311141
Pubmed	Autocrine Leukemia Inhibitory Factor Promotes Esophageal Squamous Cell Carcinoma Progression via Src Family Kinase-Dependent Yes-Associated Protein Activation.	YAP1 STAT3	3.87e-06	3	40	2	33004621
Pubmed	Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.	STAT3 MITF	3.87e-06	3	40	2	16368885
Pubmed	2-Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor-κB signaling by inhibiting Janus kinase 2 and IκB kinase.	IKBKB STAT3	3.87e-06	3	40	2	24450414
Pubmed	YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.	KIF4A YAP1	3.87e-06	3	40	2	34003522
Pubmed	Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.	STAT3 MITF	3.87e-06	3	40	2	15572665
Pubmed	Osteal Tissue Macrophages Are Involved in Endplate Osteosclerosis through the OSM-STAT3/YAP1 Signaling Axis in Modic Changes.	YAP1 STAT3	3.87e-06	3	40	2	32690652
Pubmed	Co-activator SRC-1 is dispensable for transcriptional control by STAT3.	NCOA1 STAT3	3.87e-06	3	40	2	19203349
Pubmed	Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a.	NCOA1 STAT3	3.87e-06	3	40	2	11773079
Pubmed	Length-dependent poleward flux of sister kinetochore fibers promotes chromosome alignment.	KIF4A NUMA1	3.87e-06	3	40	2	35926461
Pubmed	DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha.	NCOA1 STAT3	7.73e-06	4	40	2	23874500
Pubmed	STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.	STAT3 MITF	7.73e-06	4	40	2	33323974
Pubmed	Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.	IKBKB STAT3	7.73e-06	4	40	2	19345327
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	KIF4A TGM3 BAZ2A STRBP PCM1 SPTAN1 NUMA1	8.67e-06	653	40	7	22586326
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SCYL1 STK10 KRT76 YAP1 NUMA1 MITF	9.28e-06	430	40	6	35044719
Pubmed	IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis.	IKBKB STAT3	1.29e-05	5	40	2	26260587
Pubmed	YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.	YAP1 STAT3	1.29e-05	5	40	2	27215660
Pubmed	A gp130-Src-YAP module links inflammation to epithelial regeneration.	YAP1 STAT3	1.29e-05	5	40	2	25731159
Pubmed	Hepatitis C virus infection protein network.	CEP85 GOLGA2 STAT3	1.57e-05	42	40	3	18985028
Pubmed	Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.	PSPC1 STAT3 NUMA1 RNF20	1.58e-05	131	40	4	34551306
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	YAP1 RABEP1 GOLGA2	1.68e-05	43	40	3	34672947
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	KIF4A PSPC1 BAZ2A STRBP NUMA1	1.79e-05	283	40	5	30585729
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	STK10 KIF4A KRT76 SPTAN1 NUMA1	1.83e-05	284	40	5	29459677
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	STK10 KIF4A YAP1 GOLGA2 PCM1 NUMA1	2.25e-05	503	40	6	16964243
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	STK10 BAZ2A YAP1 PCM1 SPTAN1 NUMA1 RNF20	2.59e-05	774	40	7	15302935
Pubmed	The mouse C/EBPdelta gene promoter is regulated by STAT3 and Sp1 transcriptional activators, chromatin remodeling and c-Myc repression.	NCOA1 STAT3	2.70e-05	7	40	2	17471507
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	NCOA1 CEP85 PSPC1 RRP36	2.84e-05	152	40	4	38360978
Pubmed	Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis.	GOLGA2 PCM1	3.60e-05	8	40	2	24648492
Pubmed	Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER.	RABEP1 GOLGA2	3.60e-05	8	40	2	11718716
Pubmed	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.	NCOA1 IKBKB	3.60e-05	8	40	2	11971985
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	MAP7D2 SACS PCM1 SPTAN1 NUMA1	3.85e-05	332	40	5	37433992
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SCYL1 GOLGA2 PCM1 SPTAN1 ACBD5 NUMA1	4.43e-05	568	40	6	37774976
Pubmed	Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice.	IKBKB STAT3	4.62e-05	9	40	2	24211183
Pubmed	Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest.	YAP1 MITF	4.62e-05	9	40	2	25466249
Pubmed	Phenotypic annotation of the mouse X chromosome.	KIF4A MAP7D2 PDZD4	4.84e-05	61	40	3	20548051
Pubmed	Gut microbiome and anticancer immune response: really hot Sh*t!	IKBKB STAT3	5.77e-05	10	40	2	24832470
Pubmed	RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain.	STAT3 RNF20	5.77e-05	10	40	2	28984873
Pubmed	DNA sequence and analysis of human chromosome 9.	PLGRKT STRBP GOLGA2 SPTAN1 RNF20	6.43e-05	370	40	5	15164053
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KIF4A DNAJC17 PCM1 SPTAN1 HAUS5 RNF20	8.92e-05	645	40	6	25281560
Pubmed	A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.	YAP1 STAT3	9.98e-05	13	40	2	32929274
Pubmed	Yeast two-hybrid screens implicate DISC1 in brain development and function.	GOLGA2 SPTAN1	9.98e-05	13	40	2	14623284
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF21B KIF4A RABEP1 GOLGA2 PCM1 SPTAN1 NUMA1	1.02e-04	963	40	7	28671696
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	KIF4A MAP7D2 UBAC2 HAUS5	1.03e-04	212	40	4	33853758
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	KIF4A PSPC1 STRBP STAT3 HAUS5	1.15e-04	419	40	5	33001583
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	NCOA1 KMT2C	1.16e-04	14	40	2	12482968
Pubmed	Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers.	YAP1 STAT3	1.16e-04	14	40	2	36787740
Pubmed	Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.	YAP1 MITF	1.16e-04	14	40	2	33075808
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	KIF4A DNAJC17 PSPC1 YAP1 STAT3 NUMA1 RNF20	1.41e-04	1014	40	7	32416067
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CEP85 PSPC1 STRBP GOLGA2 PCM1 SPTAN1 STAT3 NUMA1	1.43e-04	1371	40	8	36244648
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PSPC1 SACS RRP36 STRBP PCM1 HAUS5 NUMA1	1.50e-04	1024	40	7	24711643
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CEP85 YAP1 RABEP1 PCM1 SPTAN1	1.54e-04	446	40	5	24255178
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SCYL1 STK10 CEP85 YAP1 GOLGA2 HAUS5 MITF	1.63e-04	1038	40	7	26673895
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	KIF4A DNAJC17 PSPC1 GOLGA2 SPTAN1 STAT3 NUMA1 RNF20	1.77e-04	1415	40	8	28515276
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	STK10 DNAJC17 CEP85 PSPC1 GOLGA2	2.00e-04	472	40	5	38943005
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MAP7D2 KRT76 PSPC1 SACS RRP36 STRBP SPTAN1 NUMA1	2.01e-04	1442	40	8	35575683
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SCYL1 KIF4A PSPC1 STRBP GOLGA2 SPTAN1	2.08e-04	754	40	6	35906200
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MTX1 RRP36 PLGRKT GOLGA2 PCM1 STAT3	2.08e-04	754	40	6	33060197
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	GOLGA2 PCM1 SPTAN1 STAT3	2.13e-04	256	40	4	33397691
Pubmed	Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.	YAP1 STAT3	2.18e-04	19	40	2	28067668
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	SMG5 MTX1 SPTAN1 ACBD5	2.29e-04	261	40	4	33277362
Pubmed	Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye.	YAP1 MITF	2.42e-04	20	40	2	27616714
Pubmed	Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability.	SCYL1 GOLGA2	2.42e-04	20	40	2	29437892
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA1 KIF4A YAP1 RNF20	2.53e-04	268	40	4	33640491
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCYL1 UBAC2 CEP85 MTX1 PSPC1 PLGRKT BAZ2A ACBD5	2.58e-04	1496	40	8	32877691
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	KIF4A PSPC1 STRBP NUMA1	2.64e-04	271	40	4	32433965
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	KIF21B KMT2C YAP1 CCDC136 GOLGA2 SPTAN1 HAUS5	2.65e-04	1124	40	7	21900206
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOA1 IKBKB	2.67e-04	21	40	2	19596656
Pubmed	Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration.	STAT3 MITF	2.67e-04	21	40	2	21576358
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	KIF4A PSPC1 SPTAN1 NUMA1 RNF20	2.76e-04	506	40	5	30890647
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	RABEP1 GOLGA2 RNF20	2.87e-04	111	40	3	22558309
Pubmed	Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.	YAP1 MITF	2.94e-04	22	40	2	29249622
Pubmed	Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation.	YAP1 STAT3	2.94e-04	22	40	2	28094771
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	MTX1 PSPC1 PLGRKT STRBP HAUS5	3.00e-04	515	40	5	31617661
Pubmed	Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis.	YAP1 PCM1	3.50e-04	24	40	2	22333836
Pubmed	Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.	YAP1 RABEP1	3.50e-04	24	40	2	37100772
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	GOLGA2 SPTAN1 STAT3 NUMA1 RNF20	3.66e-04	538	40	5	28524877
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	KIF21B PSPC1 SPTAN1 HAUS5 NUMA1 RNF20	3.88e-04	847	40	6	35235311
Pubmed	Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.	YAP1 GOLGA2	4.12e-04	26	40	2	24384391
Pubmed	The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.	NCOA1 STAT3	4.45e-04	27	40	2	26469385
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	SCYL1 RABEP1 SPTAN1	4.66e-04	131	40	3	31006538
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CEP85 YAP1 RABEP1 GOLGA2 PCM1	5.48e-04	588	40	5	38580884
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	KIF4A SPTAN1 NUMA1 RNF20	5.68e-04	332	40	4	32786267
Pubmed	Tagging genes with cassette-exchange sites.	KMT2C SMG5 YAP1 STRBP	5.88e-04	335	40	4	15741177
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SMG5 CEP85 SACS RABEP1 PCM1 SPTAN1 STAT3	5.92e-04	1285	40	7	35914814
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	KIF4A KMT2C BAZ2A YAP1 NUMA1 RNF20 MITF	6.17e-04	1294	40	7	30804502
Pubmed	Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm.	IKBKB STAT3	6.26e-04	32	40	2	19500387
Pubmed	The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.	GOLGA2 SPTAN1	6.26e-04	32	40	2	23704327
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SCYL1 PSPC1 BAZ2A YAP1	6.28e-04	341	40	4	32971831
Interaction	NDC80 interactions	MAP7D2 CEP85 PSPC1 CCDC136 GOLGA2 PCM1 HAUS5 ACBD5	1.51e-07	312	40	8	int:NDC80
Interaction	LCA5L interactions	KRT76 GBP5 CCDC136 PCM1	3.51e-07	30	40	4	int:LCA5L
Interaction	WWTR1 interactions	CEP85 YAP1 RABEP1 PCM1 SPTAN1 STAT3 HAUS5 NUMA1	1.48e-06	422	40	8	int:WWTR1
Interaction	NCOA6 interactions	NCOA1 KMT2C YAP1 GOLGA2 NUMA1	9.67e-06	145	40	5	int:NCOA6
Interaction	CCDC87 interactions	YAP1 GOLGA2 STAT3	1.25e-05	23	40	3	int:CCDC87
Interaction	CFAP184 interactions	SMG5 CCDC136 PCM1 HAUS5 RNF20	1.65e-05	162	40	5	int:CFAP184
Interaction	SMARCE1 interactions	SCYL1 NCOA1 YAP1 CCDC136 GOLGA2 NUMA1	2.02e-05	287	40	6	int:SMARCE1
Interaction	EGR2 interactions	NCOA1 KMT2C GOLGA2 RNF20 MITF	2.15e-05	171	40	5	int:EGR2
Interaction	UBTFL1 interactions	RABEP1 CCDC136 GOLGA2	3.13e-05	31	40	3	int:UBTFL1
Interaction	RASSF8 interactions	YAP1 CCDC136 GOLGA2 PCM1	3.14e-05	91	40	4	int:RASSF8
Interaction	SPICE1 interactions	MAP7D2 CEP85 GOLGA2 PCM1 HAUS5	3.65e-05	191	40	5	int:SPICE1
Interaction	ADRB2 interactions	GBP5 SACS BAZ2A ABCA7 STAT3 MITF	5.14e-05	339	40	6	int:ADRB2
Interaction	RAB33B interactions	RABEP1 CCDC136 GOLGA2	6.80e-05	40	40	3	int:RAB33B
Interaction	USP28 interactions	PCM1 STAT3 HAUS5 NUMA1	7.33e-05	113	40	4	int:USP28
Interaction	SMARCB1 interactions	SCYL1 KMT2C YAP1 GOLGA2 SPTAN1 NUMA1	7.61e-05	364	40	6	int:SMARCB1
Interaction	FOXC1 interactions	PSPC1 YAP1 STAT3 NUMA1 RNF20	8.45e-05	228	40	5	int:FOXC1
Interaction	WHAMMP3 interactions	YAP1 GOLGA2 HAUS5 RNF20	8.96e-05	119	40	4	int:WHAMMP3
Interaction	LENG1 interactions	SCYL1 RABEP1 CCDC136 GOLGA2	8.96e-05	119	40	4	int:LENG1
Interaction	SNW1 interactions	NCOA1 STK10 KIF4A DNAJC17 YAP1 RABEP1 GOLGA2 SPTAN1	9.21e-05	747	40	8	int:SNW1
Interaction	TET1 interactions	PSPC1 YAP1 GOLGA2	9.70e-05	45	40	3	int:TET1
Interaction	AR interactions	NCOA1 KIF4A KMT2C PSPC1 YAP1 PCM1 STAT3 NUMA1 RNF20	1.12e-04	992	40	9	int:AR
Interaction	BTRC interactions	TGM3 SMG5 IKBKB PLGRKT YAP1 PCM1 ACBD5 MITF	1.19e-04	775	40	8	int:BTRC
Interaction	CEP95 interactions	CCDC136 GOLGA2 PCM1	1.33e-04	50	40	3	int:CEP95
Interaction	H2BC3 interactions	KIF4A KMT2C YAP1 SPTAN1 NUMA1 RNF20	1.38e-04	406	40	6	int:H2BC3
Interaction	WASHC3 interactions	RABEP1 GOLGA2 PCM1 RNF20	1.42e-04	134	40	4	int:WASHC3
Interaction	P4HA2 interactions	SCYL1 MAP7D2 PSPC1 SACS	1.59e-04	138	40	4	int:P4HA2
Interaction	RNF8 interactions	TGM3 CEP85 IKBKB YAP1 SPTAN1 RNF20	1.69e-04	421	40	6	int:RNF8
Interaction	DISC1 interactions	PSPC1 CCDC136 GOLGA2 PCM1 SPTAN1 RNF20	1.87e-04	429	40	6	int:DISC1
Interaction	NUP62 interactions	GOLGA2 STAT3 ACBD5 NUMA1 RNF20	1.96e-04	273	40	5	int:NUP62
Interaction	CPEB1 interactions	SMG5 CEP85 GBP5 STRBP	1.97e-04	146	40	4	int:CPEB1
Interaction	GAS5 interactions	YAP1 STAT3	2.09e-04	11	40	2	int:GAS5
Interaction	SAV1 interactions	CEP85 YAP1 PCM1 SPTAN1	2.24e-04	151	40	4	int:SAV1
Interaction	KRT19 interactions	KRT76 CEP85 YAP1 PCM1 HAUS5	2.28e-04	282	40	5	int:KRT19
Interaction	ZNF280C interactions	GOLGA2 PCM1 NUMA1	2.41e-04	61	40	3	int:ZNF280C
Interaction	CCDC6 interactions	CEP85 YAP1 RABEP1 CCDC136 GOLGA2	2.44e-04	286	40	5	int:CCDC6
Interaction	SUMO1 interactions	NCOA1 RRP36 YAP1 NUMA1 MITF	2.47e-04	287	40	5	int:SUMO1
Interaction	FAM9C interactions	KIF4A RABEP1 CCDC136	2.65e-04	63	40	3	int:FAM9C
Interaction	FUBP3 interactions	KIF21B SMG5 CEP85 IKBKB PSPC1	2.90e-04	297	40	5	int:FUBP3
Interaction	TAB3 interactions	IKBKB YAP1 STAT3	3.04e-04	66	40	3	int:TAB3
Interaction	JUN interactions	NCOA1 KMT2C IKBKB PSPC1 YAP1 STAT3	3.05e-04	470	40	6	int:JUN
Interaction	FNBP4 interactions	DNAJC17 PLGRKT YAP1	3.32e-04	68	40	3	int:FNBP4
Interaction	PINK1 interactions	TGM3 YAP1 GOLGA2 PCM1 SPTAN1 STAT3 NUMA1	3.38e-04	679	40	7	int:PINK1
Interaction	CCDC120 interactions	YAP1 RABEP1 CCDC136 GOLGA2	3.45e-04	169	40	4	int:CCDC120
Interaction	KMT2D interactions	KMT2C UBAC2 YAP1 GOLGA2	3.45e-04	169	40	4	int:KMT2D
Interaction	FAM50B interactions	RABEP1 CCDC136 GOLGA2	3.47e-04	69	40	3	int:FAM50B
Interaction	KXD1 interactions	RABEP1 CCDC136 NUMA1 RNF20	3.52e-04	170	40	4	int:KXD1
Interaction	SMG7 interactions	NCOA1 SMG5 CEP85 PCM1 RNF20	4.02e-04	319	40	5	int:SMG7
Interaction	EED interactions	SCYL1 KIF4A PSPC1 PLGRKT BAZ2A STRBP PCM1 SPTAN1 STAT3 NUMA1	4.04e-04	1445	40	10	int:EED
Interaction	CEP63 interactions	CEP85 PCM1 SPTAN1 HAUS5	4.28e-04	179	40	4	int:CEP63
Interaction	KRT75 interactions	KRT76 YAP1 GOLGA2 NUMA1	4.47e-04	181	40	4	int:KRT75
Interaction	H2AC4 interactions	KMT2C YAP1 STRBP SPTAN1 NUMA1 RNF20	4.52e-04	506	40	6	int:H2AC4
Interaction	WT1 interactions	YAP1 CCDC136 GOLGA2	4.61e-04	76	40	3	int:WT1
Interaction	HAUS1 interactions	CCDC136 GOLGA2 PCM1 HAUS5	4.66e-04	183	40	4	int:HAUS1
Interaction	ZNF774 interactions	RABEP1 CCDC136 GOLGA2	5.16e-04	79	40	3	int:ZNF774
Interaction	NEBL interactions	CCDC136 GOLGA2 PCM1	5.16e-04	79	40	3	int:NEBL
Interaction	HNF1A interactions	NCOA1 KMT2C STAT3	5.35e-04	80	40	3	int:HNF1A
Interaction	FAM120C interactions	UBAC2 SMG5 CEP85 PCM1	5.47e-04	191	40	4	int:FAM120C
Interaction	TPGS1 interactions	GOLGA2 PCM1 STAT3	5.55e-04	81	40	3	int:TPGS1
Interaction	SIRT7 interactions	KIF4A TGM3 BAZ2A STRBP PCM1 SPTAN1 NUMA1	5.85e-04	744	40	7	int:SIRT7
Interaction	SMG5 interactions	SMG5 CEP85 PCM1	6.17e-04	84	40	3	int:SMG5
Interaction	GATA2 interactions	KMT2C GOLGA2 SPTAN1 STAT3	6.38e-04	199	40	4	int:GATA2
Interaction	KAT5 interactions	CCDC136 GOLGA2 PCM1 SPTAN1 STAT3	6.79e-04	358	40	5	int:KAT5
Interaction	SPATA2 interactions	IKBKB GOLGA2 PCM1	6.84e-04	87	40	3	int:SPATA2
Interaction	TPX2 interactions	IKBKB RRP36 YAP1 GOLGA2	7.00e-04	204	40	4	int:TPX2
Interaction	PRPH interactions	KRT76 SACS YAP1 GOLGA2	7.00e-04	204	40	4	int:PRPH
Interaction	ZNF197 interactions	CCDC136 SPTAN1	7.14e-04	20	40	2	int:ZNF197
Interaction	TEDC2 interactions	STK10 KIF4A SPTAN1 NUMA1	7.26e-04	206	40	4	int:TEDC2
Interaction	EEF1AKMT3 interactions	KIF4A IKBKB GOLGA2 STAT3 HAUS5	7.32e-04	364	40	5	int:EEF1AKMT3
Cytoband	11q13	SCYL1 YAP1 NUMA1	1.53e-04	118	40	3	11q13
Cytoband	9q34.11	GOLGA2 SPTAN1	9.92e-04	53	40	2	9q34.11
Cytoband	Ensembl 112 genes in cytogenetic band chr1q22	SMG5 MTX1	1.77e-03	71	40	2	chr1q22
Cytoband	19q13.12	ZNF781 HAUS5	1.82e-03	72	40	2	19q13.12
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF4A	1.42e-03	46	22	2	622
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	DNAJC17 SACS	1.61e-03	49	22	2	584
GeneFamily	PHD finger proteins	KMT2C BAZ2A	5.31e-03	90	22	2	88
GeneFamily	Basic helix-loop-helix proteins	NCOA1 MITF	7.83e-03	110	22	2	420
Coexpression	GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN	KIF21B STK10 RABEP1 ACBD5 MITF	1.30e-05	200	40	5	M9763
Coexpression	GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN	KIF21B NCOA1 RABEP1 SPTAN1 ACBD5	1.30e-05	200	40	5	M9765
Coexpression	GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP	KIF21B IKBKB PSPC1 SACS ABCA7	1.30e-05	200	40	5	M4456
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	SLC24A3 SACS STRBP RABEP1 PCM1 RNF20 MITF	5.41e-05	656	40	7	M18979
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	KIF21B NCOA1 STK10 KMT2C GBP5 SACS PCM1 SPTAN1 STAT3 NUMA1	6.10e-05	1492	40	10	M40023
Coexpression	HEVNER_CORTEX_APICAL_AND_BASAL_INTERMEDIATE_PROGENITOR_CELLS	BAZ2A CCDC136 NUMA1	8.18e-05	55	40	3	MM397
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	NCOA1 MAP7D2 SLC24A3 KMT2C PLGRKT STRBP CCDC136 STAT3	5.09e-05	743	39	8	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2	NCOA1 MAP7D2 SLC24A3 KMT2C PLGRKT STRBP CCDC136 STAT3	5.28e-05	747	39	8	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLC24A3 NAALADL1 CCDC136 MITF	2.71e-05	194	40	4	d8f367beab16a3186821e42311947b6c9e99978c
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B BAZ2A STRBP PCM1	2.94e-05	198	40	4	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	NCOA1 STK10 GBP5 PDZD4	2.94e-05	198	40	4	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	NCOA1 STK10 GBP5 PDZD4	2.94e-05	198	40	4	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B BAZ2A STRBP PCM1	2.94e-05	198	40	4	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	KIF21B BAZ2A STRBP PCM1	2.94e-05	198	40	4	ad39cce004867f083f8da1954e0cf5a263815184
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	STK10 SLC24A3 SMG5 CEP85 PCM1 NUMA1	1.13e-06	196	40	6	5318_UP
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	IKBKB BAZ2A RABEP1 GOLGA2 PCM1 SPTAN1	1.17e-06	197	40	6	5044_DN
Drug	Pargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A	STK10 GOLGA2 PCM1 HAUS5 NUMA1 MITF	1.20e-06	198	40	6	7016_DN
Drug	SU11274	STK10 STAT3 MITF	1.43e-05	27	40	3	CID009549297
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	STK10 SMG5 IKBKB SACS PCM1	1.80e-05	186	40	5	1066_DN
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; PC3; HT_HG-U133A	CEP85 IKBKB PCM1 HAUS5 NUMA1	1.99e-05	190	40	5	7305_DN
Drug	Homochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; MCF7; HT_HG-U133A	SMG5 DNAJC17 PCM1 SPTAN1 HAUS5	2.20e-05	194	40	5	5998_DN
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; MCF7; HT_HG-U133A	CEP85 IKBKB PCM1 HAUS5 NUMA1	2.20e-05	194	40	5	4839_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	IKBKB RABEP1 PCM1 HAUS5 NUMA1	2.26e-05	195	40	5	3705_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	CEP85 RABEP1 SPTAN1 NUMA1 MITF	2.26e-05	195	40	5	1665_DN
Drug	17-DMAG; Down 200; 0.1uM; HL60; HT_HG-U133A	NCOA1 IKBKB GOLGA2 PCM1 NUMA1	2.26e-05	195	40	5	6172_DN
Drug	Sulfinpyrazone [57-96-5]; Down 200; 9.8uM; MCF7; HT_HG-U133A	SMG5 BAZ2A GOLGA2 PCM1 HAUS5	2.37e-05	197	40	5	6230_DN
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; HL60; HT_HG-U133A	BAZ2A GOLGA2 PCM1 SPTAN1 STAT3	2.37e-05	197	40	5	1863_DN
Drug	Phensuximide [86-34-0]; Down 200; 21.2uM; PC3; HT_HG-U133A	SMG5 IKBKB GOLGA2 PCM1 NUMA1	2.37e-05	197	40	5	5097_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; HL60; HT_HG-U133A	NCOA1 BAZ2A ABCA7 GOLGA2 NUMA1	2.37e-05	197	40	5	2492_DN
Drug	Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A	NCOA1 SLC24A3 CEP85 IKBKB YAP1	2.43e-05	198	40	5	7450_DN
Drug	Bethanechol chloride [590-63-6]; Down 200; 20.4uM; MCF7; HT_HG-U133A	SLC24A3 SMG5 GOLGA2 PCM1 NUMA1	2.43e-05	198	40	5	3537_DN
Drug	Quinic acid [86-68-0]; Up 200; 19.6uM; PC3; HT_HG-U133A	ABCA7 GOLGA2 PCM1 SPTAN1 HAUS5	2.43e-05	198	40	5	7317_UP
Drug	Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A	BAZ2A ABCA7 RABEP1 GOLGA2 NUMA1	2.43e-05	198	40	5	6345_UP
Drug	Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; HL60; HT_HG-U133A	NCOA1 SMG5 IKBKB PCM1 SPTAN1	2.43e-05	198	40	5	2352_DN
Drug	PS1145	IKBKB STAT3	1.08e-04	9	40	2	ctd:C456319
Drug	Digitoxigenin [143-62-4]; Up 200; 10.6uM; HL60; HT_HG-U133A	SMG5 PSPC1 SPTAN1 NUMA1	1.85e-04	162	40	4	1339_UP
Drug	napabucasin	IKBKB YAP1 STAT3	1.94e-04	64	40	3	ctd:C000621033
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	STK10 DNAJC17 HAUS5 NUMA1	2.54e-04	176	40	4	1212_DN
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; PC3; HT_HG-U133A	SMG5 DNAJC17 SPTAN1 HAUS5	2.71e-04	179	40	4	4554_DN
Drug	retinoic acid; Up 200; 1uM; HL60; HG-U133A	KIF21B TGM3 IKBKB NUMA1	3.01e-04	184	40	4	390_UP
Drug	Bisacodyl [603-50-9]; Down 200; 11uM; MCF7; HT_HG-U133A	STK10 DNAJC17 SACS HAUS5	3.39e-04	190	40	4	3297_DN
Drug	Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SLC24A3 IKBKB RABEP1 MITF	3.46e-04	191	40	4	4811_DN
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	SLC24A3 IKBKB PCM1 NUMA1	3.46e-04	191	40	4	3926_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; PC3; HT_HG-U133A	DNAJC17 ABCA7 RABEP1 NUMA1	3.53e-04	192	40	4	4267_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; PC3; HT_HG-U133A	RABEP1 PCM1 SPTAN1 NUMA1	3.53e-04	192	40	4	4268_DN
Drug	AG-013608 [351320-38-2]; Down 200; 10uM; MCF7; HT_HG-U133A	ABCA7 RABEP1 PCM1 NUMA1	3.53e-04	192	40	4	6435_DN
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; HL60; HG-U133A	KIF21B STK10 PLGRKT NUMA1	3.53e-04	192	40	4	1419_DN
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A	STK10 RABEP1 HAUS5 MITF	3.60e-04	193	40	4	1653_DN
Drug	Norfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A	CEP85 IKBKB GOLGA2 SPTAN1	3.60e-04	193	40	4	5985_DN
Drug	Gallamine triethiodide [65-29-2]; Down 200; 4.4uM; MCF7; HT_HG-U133A	NCOA1 CEP85 IKBKB MITF	3.60e-04	193	40	4	6215_DN
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	IKBKB RABEP1 PCM1 SPTAN1	3.67e-04	194	40	4	1670_DN
Drug	Corticosterone [50-22-6]; Down 200; 11.6uM; HL60; HT_HG-U133A	NCOA1 BAZ2A GOLGA2 PCM1	3.67e-04	194	40	4	1307_DN
Drug	yohimbine; Up 200; 22.9uM; MCF7; HT_HG-U133A_EA	DNAJC17 BAZ2A RABEP1 GOLGA2	3.67e-04	194	40	4	1119_UP
Drug	Sulfameter [651-06-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	SMG5 BAZ2A GOLGA2 HAUS5	3.67e-04	194	40	4	5732_DN
Drug	Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A	STK10 CEP85 ABCA7 MITF	3.67e-04	194	40	4	7036_DN
Drug	Primidone [125-33-7]; Down 200; 18.4uM; PC3; HT_HG-U133A	SMG5 CEP85 PCM1 NUMA1	3.67e-04	194	40	4	6723_DN
Drug	SC 19220; Up 200; 10uM; PC3; HT_HG-U133A	DNAJC17 BAZ2A RABEP1 NUMA1	3.67e-04	194	40	4	7065_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	IKBKB BAZ2A PCM1 HAUS5	3.67e-04	194	40	4	2474_DN
Drug	Mefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A	SMG5 BAZ2A GOLGA2 MITF	3.67e-04	194	40	4	1364_UP
Drug	Pimozide [2062-78-4]; Up 200; 8.6uM; PC3; HT_HG-U133A	IKBKB ABCA7 RABEP1 GOLGA2	3.67e-04	194	40	4	7132_UP
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	NCOA1 IKBKB RABEP1 MITF	3.75e-04	195	40	4	1657_DN
Drug	Cefotiam hydrochloride; Down 200; 7.2uM; PC3; HT_HG-U133A	RABEP1 GOLGA2 PCM1 NUMA1	3.75e-04	195	40	4	6762_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; HL60; HT_HG-U133A	SMG5 BAZ2A PCM1 NUMA1	3.75e-04	195	40	4	2470_DN
Drug	Arecoline hydrobromide [300-08-3]; Down 200; 17uM; HL60; HT_HG-U133A	SMG5 DNAJC17 CEP85 HAUS5	3.75e-04	195	40	4	1303_DN
Drug	Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SLC24A3 IKBKB ABCA7 NUMA1	3.75e-04	195	40	4	3454_UP
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	SLC24A3 DNAJC17 GOLGA2 PCM1	3.75e-04	195	40	4	4106_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	NCOA1 SLC24A3 SPTAN1 HAUS5	3.75e-04	195	40	4	5590_DN
Drug	Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	SLC24A3 PCM1 SPTAN1 STAT3	3.75e-04	195	40	4	3519_DN
Drug	Etofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A	NCOA1 SLC24A3 BAZ2A NUMA1	3.75e-04	195	40	4	7327_DN
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	NCOA1 SMG5 DNAJC17 BAZ2A	3.75e-04	195	40	4	1144_DN
Drug	Molindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SMG5 IKBKB SPTAN1 MITF	3.75e-04	195	40	4	4784_DN
Drug	trichostatin A; Up 200; 0.1uM; ssMCF7; HG-U133A	SLC24A3 BAZ2A STAT3 MITF	3.82e-04	196	40	4	413_UP
Drug	Niflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A	IKBKB PCM1 SPTAN1 HAUS5	3.82e-04	196	40	4	5071_DN
Drug	Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; MCF7; HT_HG-U133A	SMG5 CEP85 PCM1 SPTAN1	3.82e-04	196	40	4	3333_DN
Drug	Cyclosporin A [59865-13-3]; Down 200; 3.4uM; PC3; HT_HG-U133A	SLC24A3 RABEP1 GOLGA2 SPTAN1	3.82e-04	196	40	4	4586_DN
Drug	Neomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A	GOLGA2 PCM1 HAUS5 NUMA1	3.82e-04	196	40	4	2229_DN
Drug	Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A	SMG5 IKBKB BAZ2A MITF	3.82e-04	196	40	4	7367_DN
Drug	6-Furfurylaminopurine [525-79-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A	SMG5 IKBKB PCM1 NUMA1	3.82e-04	196	40	4	6813_DN
Drug	5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA	NCOA1 BAZ2A GOLGA2 HAUS5	3.82e-04	196	40	4	960_DN
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SLC24A3 SMG5 DNAJC17 CEP85	3.82e-04	196	40	4	4834_DN
Drug	Fosfosal [6064-83-1]; Down 200; 18.4uM; HL60; HT_HG-U133A	NCOA1 DNAJC17 BAZ2A NUMA1	3.82e-04	196	40	4	2997_DN
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A	DNAJC17 GOLGA2 NUMA1 MITF	3.82e-04	196	40	4	7335_UP
Drug	Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A	SPTAN1 HAUS5 NUMA1 MITF	3.82e-04	196	40	4	3409_UP
Drug	Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A	SLC24A3 RABEP1 PCM1 HAUS5	3.82e-04	196	40	4	3541_DN
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; PC3; HT_HG-U133A	SMG5 IKBKB ABCA7 RABEP1	3.82e-04	196	40	4	6638_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	IKBKB GOLGA2 PCM1 HAUS5	3.82e-04	196	40	4	2751_DN
Drug	Sisomicin sulfate [53179-09-2]; Down 200; 2.8uM; HL60; HT_HG-U133A	NCOA1 BAZ2A PCM1 NUMA1	3.82e-04	196	40	4	2493_DN
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	CEP85 IKBKB GOLGA2 HAUS5	3.82e-04	196	40	4	6775_DN
Drug	Epirizole [18694-40-1]; Up 200; 17uM; HL60; HT_HG-U133A	NCOA1 BAZ2A RABEP1 GOLGA2	3.89e-04	197	40	4	1845_UP
Drug	Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A	KIF21B SLC24A3 PCM1 MITF	3.89e-04	197	40	4	7411_UP
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A	SMG5 BAZ2A RABEP1 PCM1	3.89e-04	197	40	4	4501_DN
Drug	Succinylsulfathiazole [116-43-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	SLC24A3 GOLGA2 PCM1 NUMA1	3.89e-04	197	40	4	4847_DN
Drug	Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	CEP85 GOLGA2 NUMA1 MITF	3.89e-04	197	40	4	7012_DN
Drug	Arecoline hydrobromide [300-08-3]; Up 200; 17uM; MCF7; HT_HG-U133A	BAZ2A ABCA7 PCM1 SPTAN1	3.89e-04	197	40	4	2657_UP
Drug	Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A	SLC24A3 BAZ2A ABCA7 SPTAN1	3.89e-04	197	40	4	3484_UP
Drug	N6-methyladenosine [1867-73-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	CEP85 RABEP1 GOLGA2 SPTAN1	3.89e-04	197	40	4	5332_DN
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SMG5 ABCA7 RABEP1 SPTAN1	3.89e-04	197	40	4	5309_UP
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; PC3; HT_HG-U133A	BAZ2A PCM1 SPTAN1 HAUS5	3.89e-04	197	40	4	7401_UP
Drug	Metyrapone [54-36-4]; Down 200; 17.6uM; PC3; HT_HG-U133A	CEP85 ABCA7 NUMA1 MITF	3.89e-04	197	40	4	4606_DN
Drug	Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SMG5 RABEP1 GOLGA2 PCM1	3.89e-04	197	40	4	5343_DN
Drug	Zalcitabine [7481-89-2]; Down 200; 19uM; MCF7; HT_HG-U133A	BAZ2A PCM1 HAUS5 MITF	3.89e-04	197	40	4	7352_DN
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	KIF21B SLC24A3 BAZ2A NUMA1	3.89e-04	197	40	4	3247_UP
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; HL60; HT_HG-U133A	NCOA1 SMG5 DNAJC17 PCM1	3.89e-04	197	40	4	1342_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A	ABCA7 PCM1 SPTAN1 NUMA1	3.89e-04	197	40	4	3622_DN
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A_EA	NCOA1 STK10 SMG5 PCM1	3.97e-04	198	40	4	1073_DN
Drug	Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A	STK10 SMG5 BAZ2A PCM1	3.97e-04	198	40	4	1377_UP
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	CEP85 IKBKB BAZ2A SPTAN1	3.97e-04	198	40	4	2068_DN
Drug	5155877; Down 200; 10uM; PC3; HT_HG-U133A	BAZ2A GOLGA2 PCM1 SPTAN1	3.97e-04	198	40	4	6569_DN
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	CEP85 BAZ2A RABEP1 GOLGA2	3.97e-04	198	40	4	6991_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; PC3; HT_HG-U133A	NCOA1 SMG5 GOLGA2 SPTAN1	3.97e-04	198	40	4	2115_DN
Drug	Kanamycin A sulfate [25389-94-0]; Down 200; 6.8uM; HL60; HG-U133A	NCOA1 SMG5 BAZ2A SPTAN1	3.97e-04	198	40	4	1609_DN
Drug	Nitrocaramiphen hydrochloride; Down 200; 10.8uM; MCF7; HT_HG-U133A	SLC24A3 CEP85 BAZ2A HAUS5	3.97e-04	198	40	4	7464_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	SMG5 GOLGA2 PCM1 SPTAN1	3.97e-04	198	40	4	1237_DN
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; MCF7; HT_HG-U133A	SMG5 CEP85 RABEP1 GOLGA2	3.97e-04	198	40	4	2640_DN
Disease	Malignant neoplasm of breast	NCOA1 MAP7D2 KRT76 IKBKB YAP1 STRBP SPTAN1 STAT3 PDZD4	1.07e-05	1074	40	9	C0006142
Disease	hypertrophic cardiomyopathy	KMT2C CCDC136 MITF	2.67e-04	92	40	3	EFO_0000538
Disease	squamous cell carcinoma (is_implicated_in)	KMT2C STAT3	2.70e-04	18	40	2	DOID:1749 (is_implicated_in)
Disease	migraine disorder, pulse pressure measurement	SLC24A3 YAP1	5.70e-04	26	40	2	EFO_0005763, MONDO_0005277
Disease	breast cancer (is_implicated_in)	IKBKB STAT3 RNF20	1.11e-03	150	40	3	DOID:1612 (is_implicated_in)
Disease	colon cancer (biomarker_via_orthology)	IKBKB STAT3	1.29e-03	39	40	2	DOID:219 (biomarker_via_orthology)
Disease	body height at birth	CEP85 STRBP	1.35e-03	40	40	2	EFO_0006784
Disease	nasopharynx carcinoma (is_marker_for)	KMT2C STAT3	1.56e-03	43	40	2	DOID:9261 (is_marker_for)
Disease	Chagas cardiomyopathy	NAALADL1 MITF	1.64e-03	44	40	2	EFO_0005529
Disease	Acute Promyelocytic Leukemia	STAT3 NUMA1	1.79e-03	46	40	2	C0023487
Disease	Squamous cell carcinoma of the head and neck	YAP1 STAT3	2.28e-03	52	40	2	C1168401

Protein segments in the cluster

Peptide	Gene	Start	Entry
DMQEQNIRLMQQLRE	RNF20	741	Q5VTR2
LVLMRLQEDMQNVLQ	ACBD5	451	Q5T8D3
RLEERQRQQMILEEM	BAZ2A	806	Q9UIF9
AMLQRLLQMQDEGRR	ABCA7	346	Q8IZY2
QFLESQRLLMRDMQR	RABEP1	286	Q15276
IMELNRMIQRLRAEI	KRT76	401	Q01546
MQEVDRQRALQQRME	KMT2C	3416	Q8NEZ4
QMRLEREQIMLQIEQ	MAP7D2	521	Q96T17
RLQQGQRAAMMNLLR	IKBKB	446	O14920
NVQRLKQMLNELMRQ	PCM1	1071	Q15154
LMNARLQLERQLIMQ	PLGRKT	21	Q9HBL7
ILRAQKMQQLRERCM	PDZD4	416	Q76G19
ALMKQMREEQQRRRL	KIF21B	761	O75037
AIQRQNEQMMQERER	GBP5	506	Q96PP8
PMQRLQNQLRRLQDM	HAUS5	146	O94927
NQEMKSAMQRLQRRL	OR4D6	291	Q8NGJ1
QQIMQLLREMQNPRE	GOLGA2	961	Q08379
MASRMLINERQRLIN	SLC24A3	346	Q9HC58
CRQQLELIRLQMEQM	CEP85	286	Q6P2H3
LMENNRNQMIQALLI	MT-CO3	151	P00414
MRQAAERQQLIARMQ	DNAJC17	281	Q9NVM6
LNQEIRMMKNQRVQL	KIF4A	636	O95239
LIDMRRNMDIRENLL	SACS	1496	Q9NZJ4
IAMMQQRIDRLALLN	NUMA1	251	Q14980
RMQRQYMERLQLLTG	MTX1	291	Q13505
RNRLMRDMAQLRLQL	SMG5	821	Q9UPR3
TDRAMRIRLLQQMEQ	SCYL1	361	Q96KG9
HRQRQLIQQQRAMLM	NCOA1	1121	Q15788
IDLMNALMRLNQIRP	STRBP	386	Q96SI9
ILRRGQNFQVLMIMN	TGM3	31	Q08188
MQLLRQQLRDAEEQM	CCDC136	296	Q96JN2
RILLRQQLMREQMQE	MITF	56	O75030
QQLMREQMQEQERRE	MITF	61	O75030
QLMLMRQDLMRRQEE	PSPC1	316	Q8WXF1
QQLEQMLTALDQMRR	STAT3	201	P40763
QRRMMLDQCLELQLF	SPTAN1	1436	Q13813
REQMQRYNQRMIEQL	STK10	781	O94804
MRLQQLQMEKERLRL	YAP1	306	P46937
LLQRMEQQEMAQQER	RRP36	171	Q96EU6
IQRQQRMELLDRQLM	UBAC2	241	Q8NBM4
TRELILMRNLMNVRN	ZNF781	191	Q8N8C0
LMRNLMNVRNVKRLL	ZNF781	196	Q8N8C0
QVRMLNDQLMLLERT	NAALADL1	651	Q9UQQ1