Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1A KIF18A DDX12P HSPA4L ABCB5 SMARCAL1 ABCC11 RNF213 AK9 DNAH14 KIF9 MDN1 RECQL5 UBA6 CHD6 DDX60L DYNC1H1 ACSL5

7.33e-0661417418GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP6V1A KIF18A DDX12P ABCB5 ABCC11 RNF213 AK9 KIF9 MDN1 RECQL5 CHD6 DDX60L DYNC1H1

1.36e-0444117413GO:0016887
PathwayREACTOME_RHOA_GTPASE_CYCLE

DOCK2 ARHGEF19 OBSCN ARHGAP35 OPHN1 FAF2 VANGL1 FARP1

4.76e-051421298MM15576
PathwayREACTOME_RHOA_GTPASE_CYCLE

DOCK2 ARHGEF19 OBSCN ARHGAP35 OPHN1 FAF2 VANGL1 FARP1

6.69e-051491298M41805
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

CALCOCO2 DNAJB1 ATP6V1A FLNB HSPA4L POLA1 BCLAF1 GART CAPZA2 NOL11 ELP1 APLP2 RO60 TTC3 SDAD1 CYFIP2 UBE2O AP2M1 MDN1 FAF2 P4HB TKT PI4KA EIF3L UBA6 AFDN CLUH DYNC1H1

7.01e-1014251752830948266
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNB ZSWIM8 EPPK1 POLA1 GART NOL11 ELP1 CUL7 IGF2BP2 UBE2O MDN1 P4HB EIF3L AFDN CLUH DYNC1H1 PPP6R3

3.99e-086531751722586326
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DNAJB1 ATP6V1A FLNB PSMG3 HSPA4L BCLAF1 CAPZA2 PON2 ELP1 RNF213 MRPL45 COG3 IFIT1 SDAD1 IGF2BP2 AP2M1 TRAFD1 MDN1 FAF2 MRPS2 EIF3L VPS35L DDX60L DYNC1H1 PPP6R3

7.07e-0814401752530833792
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DNAJB1 KIF18A ELP1 RNF213 APLP2 CUL7 ITGA5 SDAD1 CYFIP2 CEP350 IGF2BP2 PTPA NF2 P4HB VANGL1 FARP1 PI4KA SEC24B VPS13A L3MBTL3 PPP6R3

8.46e-0810491752127880917
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNB RB1 POLA1 GART RPP30 CAPZA2 NOL11 ELP1 VPS16 IGF2BP2 AP2M1 FBXO22 MDN1 FAF2 P4HB TKT PI4KA RECQL5 EIF3L SEC24B RBM7 AFDN DDX60L DYNC1H1

8.95e-0813531752429467282
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

LIN28B HSPA4L NOL11 ELP1 RNF213 MRPL45 CUL7 TTC3 IFIT1 TRMT2B SPTBN5 RMDN3 IGF2BP2 MDN1 FAF2 MRPL16 MRPS2 VANGL1 NDUFAF7 PI4KA ANGEL2 SEC24B VPS13A RBM7 CLUH

1.45e-0714961752532877691
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DOCK2 ATP6V1A FLNB EPPK1 GART COG3 RYR1 CYFIP2 TXNRD1 RMDN3 PTPA AP2M1 MDN1 FAF2 P4HB TKT HYDIN DYNC1H1

1.57e-078071751830575818
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATP6V1A FLNB CARMIL2 HSPA4L MTERF1 BCLAF1 RAPGEF4 CAPZA2 ELP1 ARHGAP35 OPHN1 CYFIP2 SLC4A1 UBE2O AP2M1 P4HB TKT FARP1 PI4KA EIF3L OSBPL6 AFDN PLCH1 DYNC1H1

2.49e-0714311752437142655
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DNAJB1 FRAS1 HSPA4L BCLAF1 RPP30 PON2 NOL11 ELP1 MRPL45 TTC3 UBE2O MDN1 FAF2 NF2 P4HB MRPS2 VANGL1 FARP1 PI4KA VPS13A UBA6 PLCH1 CLUH PPP6R3

4.95e-0714871752433957083
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DNAJB1 FLNB HSPA4L PON2 ELP1 APLP2 RMDN3 IGF2BP2 UBE2O AP2M1 FBXO22 FAF2 ACAD11 P4HB VANGL1 TKT AFDN CLUH PPP6R3

5.38e-079741751928675297
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

DNAJB1 ATP6V1A FLNB EPPK1 HSPA4L POLA1 GART CAPZA2 ELP1 ARHGAP35 TXNRD1 UBE2O AP2M1 FBXO22 FAF2 P4HB MRPS2 TKT EIF3L UBA6 CLUH DYNC1H1 PPP6R3

7.77e-0714151752328515276
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

DNAJB1 ATP6V1A FLNB HSPA4L POLA1 GART NOL11 ELP1 UBE2O MDN1 FAF2 P4HB EIF3L DYNC1H1 PPP6R3

9.33e-076381751533239621
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

DNAJB1 FLNB EPPK1 HSPA4L CAPZA2 ABCC11 IGF2BP2 TRAFD1 MDN1 FAF2 P4HB TKT EIF3L DYNC1H1 PPP6R3

1.11e-066471751526618866
Pubmed

Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice.

RHOJ PLXND1 KDR

1.24e-065175321505259
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

CARMIL2 LIN28B CAPZA2 APLP2 RO60 MRPL45 COG3 ITGA5 UBE2O AP2M1 FAF2 MRPL16 P4HB MRPS2 VANGL1 EIF3L SEC24B FLRT3

1.69e-069521751838569033
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

DNAJB1 ZSWIM8 HSPA4L GART RPP30 CAPZA2 ELP1 DEPDC1 MRPL45 SDAD1 IGF2BP2 UBE2O FBXO22 FAF2 MRPL16 P4HB MRPS2 TKT ANGEL2 EIF3L PPP6R3

4.06e-0613351752129229926
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

DNAJB1 HAUS6 POLA1 BCLAF1 RPP30 NOL11 ARHGAP35 TTC3 CYFIP2 CEP350 IGF2BP2 NF2 TKT FARP1 CLUH

4.37e-067241751536232890
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ATP6V1A FLNB EPPK1 BCLAF1 GART CAPZA2 NOL11 ELP1 CUL7 CEP350 IGF2BP2 MDN1 P4HB VANGL1 PI4KA UBA6 AFDN DYNC1H1

4.65e-0610241751824711643
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

DNAJB1 HAUS6 BCLAF1 ARHGAP35 NEK1 SETD2 UBE2O LATS1 NF2 SEC24B AFDN DYNC1H1 PPP6R3

4.71e-065491751338280479
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMARCAL1 PON2 ELP1 ITGA5 HORMAD1 IFIT1 RYR1 CEP350 MDN1 FAF2 ACAD11 MRPS2 VPS13A CHD6

4.81e-066381751431182584
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

ATP6V1A NOL11 TTC3 SDAD1 RYR1 ADH7 AP2M1 NF2 P4HB MRPS2 TKT PI4KA EIF3L RBM7 PLCH1

4.98e-067321751534732716
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FLNB RB1 POLA1 OBSCN RNF213 DNAH14 RYR1 SAMD9L MDN1 PI4KA EIF3L VPS13A XXYLT1 CHD6 DYNC1H1

5.32e-067361751529676528
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

DNAJB1 KIF18A FLNB HAUS6 RB1 BCLAF1 HAUS2 CEP350 UBE2O PI4KA RECQL5 DZIP3 CHD6 L3MBTL3

5.45e-066451751425281560
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

ATP6V1A GART TXNRD1 FSIP2 AP2M1 FAF2 NF2 P4HB TKT FARP1 SCN7A AFDN DYNC1H1

5.61e-065581751335063084
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ATP6V1A LIN28B BCLAF1 SMARCAL1 RPP30 CAPZA2 NOL11 ELP1 SDAD1 CEP350 IGF2BP2 AP2M1 ACAD11 P4HB MRPS2 TKT FARP1 RBM7 ROS1 FLRT3 DYNC1H1

6.10e-0613711752136244648
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

ATP6V1A EPPK1 RPP30 LATS1 MDN1 FAF2 VANGL1 FARP1 CLUH DYNC1H1 PPP6R3

6.31e-063991751137536630
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

DNAJB1 ATP6V1A GART PON2 ELP1 APLP2 RMDN3 TRAFD1 FAF2 P4HB VANGL1 VPS13A CADPS2 PPP6R3

6.71e-066571751436180527
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DNAJB1 RPP30 NOL11 APLP2 SDAD1 CYFIP2 RMDN3 SETD2 MDN1 ACAD11 P4HB MRPS2 VANGL1 FARP1 PI4KA RECQL5 EIF3L SEC24B RBM7 AFDN CHD6 PPP6R3

6.93e-0614971752231527615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 BCLAF1 RAPGEF4 CAPZA2 GRIK3 BTBD9 TTC3 CYFIP2 UBE2O MDN1 FARP1 PI4KA DZIP3 UBA6 AFDN KCNT1 DYNC1H1

8.20e-069631751728671696
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 HAUS6 RNF213 CUL7 BTBD9 ARHGAP35 CEP350 NEK1 SETD2 AP2M1 SAMD9L PLCH1

8.39e-064931751215368895
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

GPRASP1 EPPK1 GCNT3 ELP1 SNRK MRPL45 TTC3 RYR1 OPHN1 MDN1 RECQL5 VPS35L KDR CSMD1 CADPS2 CA5B HYDIN INVS PPP6R3 SMAD7

8.95e-0612931752015342556
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SPATA7 ATP6V1A HAUS6 BCLAF1 RNF213 PLXND1 CEP350 FAF2 NF2 VANGL1 PI4KA SEC24B VPS13A AFDN DYNC1H1

1.01e-057771751535844135
Pubmed

Functional proteomics mapping of a human signaling pathway.

CALCOCO2 KIF18A FLNB APLP2 TTC3 ZNF341 EIF3L UBA6 AFDN CHD6 DYNC1H1 INVS SMAD7

1.03e-055911751315231748
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SPATA7 DNAJB1 KIF18A HAUS6 RB1 CAPZA2 APLP2 NEK1 AP2M1 EFHC1 TRAFD1 P4HB EIF3L SEC24B OSBPL6 DZIP3 AFDN CLUH DYNC1H1 INVS

1.22e-0513211752027173435
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

ATP6V1A RPP30 RNF213 APLP2 VPS16 BTBD9 AP2M1 TRAFD1 FAF2 ACAD11 MRPS2 VANGL1 PPP6R3

1.30e-056041751338803224
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 ARHGEF19 EPPK1 ZNF585A DOCK9 OBSCN PLXND1 ARHGAP35 ITGA5 TTC3 RYR1 MDN1 NF2 ZNF341 PI4KA XXYLT1 DYNC1H1 SMAD7

1.30e-0511051751835748872
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

FLNB EPPK1 BCLAF1 NOL11 SDAD1 IGF2BP2 UBE2O P4HB TKT EIF3L AFDN DDX60L DYNC1H1 ACSL5

1.62e-057111751433022573
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

ATP6V1A EPPK1 RB1 LIN28B BCLAF1 NEK1 UBE2O ACAD11 P4HB VANGL1 RECQL5 OSBPL6

1.82e-055331751225544563
Pubmed

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.

RAG1 TLR7 LATS1

2.01e-0511175327912060
Pubmed

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

HAUS6 HAUS2 RBM7

2.01e-0511175319369198
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATP6V1A FLNB OBSCN PON2 RNF213 VPS54 BTBD9 ARHGAP35 COG3 TTC3 DNAH14 SGK2 NF2 FARP1 VPS35L XXYLT1 UBA6 CHD6 CSMD1 INVS CREB3L2

2.10e-0514891752128611215
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

DNAJB1 HSPA4L RPP30 CAPZA2 ELP1 RO60 VPS16 AP2M1 FAF2 ACAD11 MRPL16 P4HB MRPS2 VANGL1 EIF3L CLUH

2.12e-059311751627432908
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DNAJB1 ATP6V1A HSPA4L ELP1 APLP2 RO60 RMDN3 UBE2O TRAFD1 FAF2 PI4KA EIF3L SEC24B XXYLT1 DYNC1H1 PPP6R3

2.44e-059421751631073040
Pubmed

In Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells.

NF2 CHEK2

2.52e-052175232441531
Pubmed

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8+ T Cell Compartment by Negatively Regulating Tonic TCR Triggering.

DOCK2 RAG1

2.52e-052175231740487
Pubmed

Expression of a single, viral oncoprotein in skin epithelium is sufficient to recruit lymphocytes.

RAG1 RB1

2.52e-052175223469070
Pubmed

Ubiquitin Activating Enzyme UBA6 Regulates Th1 and Tc1 Cell Differentiation.

RAG1 UBA6

2.52e-052175235011668
Pubmed

Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110.

DNAJB1 HSPA4L

2.52e-052175224091676
Pubmed

Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa.

KIF9 HYDIN

2.52e-052175232072696
Pubmed

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

RAG1 SMAD7

2.52e-052175224480808
Pubmed

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

RAG1 SMAD7

2.52e-052175219192480
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

2.52e-052175231400758
Pubmed

RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.

RHOJ ITGA5

2.52e-052175232302585
Pubmed

Phosphorylated retinoblastoma protein stimulates DNA polymerase alpha.

RB1 POLA1

2.52e-05217529395244
Pubmed

Alternative splicing of CHEK2 and codeletion with NF2 promote chromosomal instability in meningioma.

NF2 CHEK2

2.52e-052175222355270
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

2.52e-052175237450367
Pubmed

Study of differential gene expression between invasive multifocal/ multicentric and unifocal breast cancer.

ABCB5 ABCC11

2.52e-052175229552773
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

CALCOCO2 ATP6V1A FLNB EPPK1 GART PON2 ITGA5 PTPA AP2M1 FBXO22 P4HB VANGL1 EIF3L SEC24B CHEK2 XXYLT1 CLUH DYNC1H1 PPP6R3

3.20e-0512971751933545068
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

DNAJB1 FLNB CHST10 CARMIL2 HSPA4L BCLAF1 RPP30 CEP350 RMDN3 UBE2O RECQL5 DYNC1H1 PPP6R3

3.81e-056701751322990118
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CAPZA2 CEP350 AP2M1 FBXO22 P4HB TKT DYNC1H1

4.04e-05182175731067453
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

FLNB HSPA4L GART ELP1 RNF213 BTBD9 TXNRD1 P4HB TKT EIF3L CHEK2

4.59e-054951751128581483
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FLNB DOCK9 CAPN3 OBSCN ELP1 TTC3 RYR1 NF2 P4HB TKT MAD2L2

4.76e-054971751123414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

HSPA4L DOCK9 RAPGEF4 OBSCN AK9 SDAD1 FBXO22 TRAFD1 MDN1 UBA6 HYDIN

4.76e-054971751136774506
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DNAJB1 ATP6V1A FLNB PSMG3 HSPA4L POLA1 GART RPP30 CAPZA2 ELP1 RO60 COG3 TXNRD1 UBE2O P4HB EIF3L UBA6 CLUH DYNC1H1 PPP6R3

4.77e-0514551752022863883
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

BCLAF1 CAPN3 CYFIP2 RMDN3 P4HB AFDN DYNC1H1 PPP6R3

4.84e-05255175815324660
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

FLNB EPPK1 GART APLP2 TTC3 EYS NF2 FARP1 DYNC1H1

5.08e-05332175937433992
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

VPS54 FARP1 DZIP3 CSMD1 HYDIN

5.40e-0580175519389623
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

HTR1D ADH7 SCN7A

5.45e-051517539726281
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DNAJB1 ATP6V1A RB1 POLA1 BCLAF1 SMARCAL1 NOL11 RNF213 TXNRD1 SETD2 PTPA AP2M1 MDN1 TKT EIF3L UBA6

5.86e-0510141751632416067
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

ATP6V1A EPPK1 CAPZA2 RNF213 TXNRD1 FAF2 TKT DYNC1H1

6.18e-05264175832814769
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CALCOCO2 HSPA4L BCLAF1 NOL11 CUL7 SDAD1 CYFIP2 NEK1 AP2M1 LATS1 ACAD11 EIF3L CHEK2 DDX60L PPP6R3

6.19e-059101751536736316
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

EPPK1 LIN28B POLA1 RPP30 CAPZA2 NOL11 ELP1 VPS16 IGF2BP2 AP2M1 FAF2 EIF3L DYNC1H1

6.29e-057041751329955894
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK2 DNAJB1 ARHGEF19 EPPK1 HSPA4L DOCK9 GART CAPZA2 ARHGAP35 OPHN1 AP2M1 MRPL16 P4HB FARP1 PPP6R3

6.66e-059161751532203420
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DNAJB1 FLNB HAUS6 HSPA4L BCLAF1 GART LATS1 VANGL1 SEC24B UBA6 AFDN PLCH1 DYNC1H1

6.66e-057081751339231216
Pubmed

Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.

PON2 ELP1 SLC4A1

6.68e-0516175317137217
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

DNAJB1 EPPK1 HSPA4L MRPL45 IGF2BP2 P4HB MRPS2 ANGEL2 PPP6R3

6.97e-05346175925324306
Pubmed

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.

LATS1 NF2

7.53e-053175224012335
Pubmed

Protein disulfide isomerase A1 as a novel redox sensor in VEGFR2 signaling and angiogenesis.

P4HB KDR

7.53e-053175235984546
Pubmed

A functional role for Smad7 in sustaining colon cancer cell growth and survival.

RAG1 SMAD7

7.53e-053175224556688
Pubmed

TLR7 and TLR9 ligands regulate antigen presentation by macrophages.

RAG1 TLR7

7.53e-053175226567289
Pubmed

Toll-like receptor 7 inhibits early acute retroviral infection through rapid lymphocyte responses.

RAG1 TLR7

7.53e-053175223616654
Pubmed

PlexinD1 signaling controls domain-specific dendritic development in newborn neurons in the postnatal olfactory bulb.

RHOJ PLXND1

7.53e-053175237534039
Pubmed

Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle.

CAPN3 RYR1

7.53e-053175218676612
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FRAS1 FREM3

7.53e-053175221993971
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

DNAJB1 ATP6V1A FLNB EPPK1 HSPA4L GART CAPZA2 CYFIP2 IGF2BP2 UBE2O AP2M1 MDN1 P4HB TKT EIF3L AFDN DYNC1H1

7.53e-0511491751735446349
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DNAJB1 ATP6V1A HAUS6 BCLAF1 GART CAPZA2 ARHGAP35 NEK1 SETD2 IGF2BP2 UBE2O AP2M1 TKT SEC24B PPP6R3

8.27e-059341751533916271
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

DNAJB1 FLNB HAUS6 GART CAPZA2 IGF2BP2 FBXO22 MRPS2 TKT EIF3L DYNC1H1

9.01e-055341751135032548
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DNAJB1 ELP1 CUL7 CYFIP2 IGF2BP2 LATS1 ACAD11 NF2 AFDN PPP6R3

9.49e-054461751024255178
Pubmed

A protein interaction landscape of breast cancer.

DNAJB1 EPPK1 RB1 HSPA4L RO60 CUL7 AP2M1 MDN1 PI4KA CHEK2 CLUH PPP6R3

9.61e-056341751234591612
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

DNAJB1 HAUS6 GCNT3 RNF213 VPS16 PLXND1 COG3 SETD2 PTPA AP2M1 TRAFD1 MDN1 FAF2 VPS13A XXYLT1 FLRT3

9.92e-0510611751633845483
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

DOCK2 ATP6V1A RFK GART RPP30 RO60 VPS16 SDAD1 MRPS2 VPS35L

1.10e-044541751033226137
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

DOCK2 OBSCN RNF213 CUL7 RYR1 CYFIP2 SPTBN5

1.12e-04214175722199357
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

DNAJB1 FLNB EPPK1 IFIT1 TXNRD1 TKT

1.26e-04152175616009940
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

DNAJB1 FLNB HSPA4L RPP30 CAPZA2 RO60 TXNRD1 IGF2BP2 UBE2O TRAFD1 ACAD11 MRPS2 EIF3L RBM7 PPP6R3

1.27e-049711751533306668
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ATP6V1A HAUS6 PON2 ELP1 VPS16 SDAD1 AP2M1 AFDN CLUH DYNC1H1 PPP6R3

1.37e-045601751135241646
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

HAUS6 LIN28B POLA1 SMARCAL1 APLP2 VPS54 VPS16 HAUS2 SETD2 PTCHD1 NF2 P4HB TKT RECQL5 CHEK2 RBM7 GMPR PPP6R3

1.37e-0413271751832694731
Pubmed

Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.

RAPGEF4 PLCH1

1.50e-044175221041529
Pubmed

Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity.

RAG1 SMAD7

1.50e-044175231553906
Pubmed

Strength training with blood flow restriction diminishes myostatin gene expression.

GPRASP1 SMAD7

1.50e-044175221900845
Pubmed

IRF-5 Promotes Cell Death in CD4 T Cells during Chronic Infection.

RAG1 TLR7

1.50e-044175230067973
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KIF18A VPS54 RYR1 FARP1 DZIP3 CSMD1 HYDIN

1.20e-041811107694
GeneFamilyHAUS augmin like complex

HAUS6 HAUS2

1.00e-0381102581
GeneFamilyReceptor Tyrosine Kinases|CD molecules

INSRR KDR ROS1

1.84e-03401103321
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

1.95e-03111102559
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_1

FLNB RHOJ ZNF366 DOCK9 RAPGEF4 PON2 PLXND1 ITGA5 IFIT1 IGF2BP2 AFDN KDR ITM2A

8.84e-0644017513M39039
CoexpressionJINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_UP

FLNB EPPK1 HSPA4L APLP2 CYFIP2 PTCHD1 IGF2BP2 FBXO22 PI4KA VPS13A FLRT3 DYNC1H1

1.08e-0538217512M38972
CoexpressionHAY_BONE_MARROW_ERYTHROBLAST

KIF18A RFK HAUS6 PSMG3 POLA1 GART RPP30 HMBS DEPDC1 MRPL45 HAUS2 SLC4A1 TXNRD1 RMDN3 NEK1 KIF9 IGF2BP2 AP2M1 MDN1 MRPL16 MRPS2 VANGL1 CHEK2

1.37e-05127117523M39197
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_1_CELL

FLNB FRAS1 DOCK9 ITGA5 DNAH14 FBXO22 SCUBE3 FLRT3 THNSL2 ITM2A

3.04e-0529417510M45674
CoexpressionBENPORATH_CYCLING_GENES

DNAJB1 PSMG3 POLA1 BCLAF1 HORMAD1 IFIT1 TXNRD1 EFHC1 MRPS2 VANGL1 CHEK2 OSBPL6 DZIP3 AFDN PPP6R3

3.20e-0564817515M8156
CoexpressionWHITFIELD_CELL_CYCLE_G2_M

DNAJB1 PSMG3 DEPDC1 TXNRD1 OIT3 VANGL1 DZIP3 AFDN

5.82e-051981758M2077
CoexpressionGSE5589_LPS_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN

VPS16 ARHGAP35 ITGA5 RYR1 MRPS2 TKT EIF3L XXYLT1

6.03e-051991758M6632
CoexpressionGSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN

ZSWIM8 PSMG3 RNF213 MDN1 RECQL5 DAPP1 CLUH DYNC1H1

6.25e-052001758M9484
CoexpressionGSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP

SMARCAL1 GART RNF213 TLR7 IFIT1 SAMD9L TRAFD1 MDN1

6.25e-052001758M8554
CoexpressionGSE17721_POLYIC_VS_CPG_16H_BMDC_DN

RFK NOL11 MRPL45 OPHN1 IGF2BP2 NF2 EIF3L ACSL5

6.25e-052001758M3951
CoexpressionGSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP

FLNB CAPN3 RO60 ITGA5 TXNRD1 ADH7 IGF2BP2 KDR

6.25e-052001758M9060
CoexpressionGSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

CARMIL2 RAPGEF4 RNF213 BTLA PLXND1 MDN1 VWA3B

6.92e-051501757M9139
CoexpressionAtlasFetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2

RAG1 GPRASP1 KIF18A LIN28B POLA1 DEPDC1 PLXND1 CUL7 TTC3 SLC4A1 IGF2BP2 OIT3 DAPP1 CHEK2 DZIP3 KDR ITM2A

4.61e-0841017317GSM791122_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

CALCOCO2 KIF18A RBM44 RB1 LIN28B HSPA4L POLA1 HORMAD1 NEK1 SOHLH2 MDN1 VPS13A DZIP3 UBA6

3.48e-0638517314gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

RB1 LIN28B HSPA4L HORMAD1 SOHLH2 VPS13A DZIP3

4.42e-051151737gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500

LIN28B HORMAD1 NEK1 SOHLH2 VPS13A DZIP3 UBA6

9.16e-051291737gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_500

RBM44 LIN28B HSPA4L HORMAD1 SOHLH2

9.25e-05561735gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_500
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR DDX60L ITM2A DYNC1H1

2.66e-112001751289821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 IGF2BP2 AFDN KDR ITM2A

2.99e-101921751104f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 IGF2BP2 AFDN KDR ITM2A

2.99e-1019217511c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A DYNC1H1

4.61e-102001751172ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A DYNC1H1

4.61e-10200175115c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

4.61e-1020017511a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

4.61e-1020017511d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR ITM2A

4.61e-10200175113585484c7e24e941708bee471ca607d8ccee74e6
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 IGF2BP2 AFDN KDR ITM2A

5.17e-091931751002f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 IGF2BP2 AFDN KDR ITM2A

5.17e-09193175105122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 IGF2BP2 AFDN KDR ITM2A

5.43e-091941751043f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 IGF2BP2 AFDN KDR ITM2A

5.43e-09194175101d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

GPRASP1 EPPK1 DOCK9 RAPGEF4 IFIT1 TRMT2B SAMD9L LPIN2 SCUBE3 CHD6

6.60e-0919817510ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR

7.27e-09200175102d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

7.27e-0920017510eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK9 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR ITM2A DYNC1H1

7.27e-092001751079e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

7.27e-09200175101d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

7.27e-0920017510b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

7.27e-092001751060d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L KDR ITM2A

5.80e-081871759f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

6.65e-081901759474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 KDR ITM2A

6.65e-081901759a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

7.28e-081921759c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ ZNF366 DOCK9 RAPGEF4 SNRK IGF2BP2 AFDN KDR

7.61e-0819317596e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Myeloid-TRAM3|Control / Disease group,lineage and cell class （2021.01.30）

CALCOCO2 PON2 RNF213 IFIT1 RMDN3 SAMD9L P4HB GMPR DDX60L

9.07e-081971759733ff40039d67e561c2ded7c9bd0b4353101741e
ToppCellBAL-Control-Myeloid-TRAM-TRAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CALCOCO2 PON2 RNF213 IFIT1 RMDN3 SAMD9L P4HB GMPR DDX60L

9.07e-0819717594416efdbd9c4ac3356a5dff2d535c2d7383376a9
ToppCellBAL-Control-Myeloid-TRAM-TRAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CALCOCO2 PON2 RNF213 IFIT1 RMDN3 SAMD9L P4HB GMPR DDX60L

9.07e-0819717590f1c4a328968b32874e6ebb0803e665adcbbc450
ToppCellBAL-Control-Myeloid-TRAM-TRAM3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CALCOCO2 PON2 RNF213 IFIT1 RMDN3 SAMD9L P4HB GMPR DDX60L

9.07e-081971759aafe0cd697b0b7f0756596148e0906443fdf8ef7
ToppCellBAL-Control-Myeloid-TRAM-TRAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CALCOCO2 PON2 RNF213 IFIT1 RMDN3 SAMD9L P4HB GMPR DDX60L

9.07e-081971759e131634bc67e0bd31a938a8e8df8dc752e1d0f47
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RHOJ DOCK9 RAPGEF4 PON2 SNRK ITGA5 KDR CSMD1 CADPS2

9.47e-08198175945419f2804b4be79bae6632e71c54e1af482d115
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR

1.03e-072001759dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOCK9 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR ITM2A

1.03e-072001759bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR

1.03e-0720017596f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

DOCK9 RNF213 SNRK IFIT1 IGF2BP2 SAMD9L AFDN KDR ITM2A

1.03e-072001759edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

1.03e-07200175981e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

1.03e-072001759b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

GPRASP1 DOCK9 OBSCN RNF213 BTLA IFIT1 SAMD9L MDN1 LPIN2

1.03e-072001759d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR

1.03e-072001759a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

FLNB DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

1.03e-0720017594bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLNB RHOJ ZNF366 RNF213 SNRK ITGA5 SCN7A KDR

2.77e-071631758d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN OBSCN GRIK3 ROS1 CSMD1 PLCH1 HYDIN

6.97e-0718417582cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN OBSCN GRIK3 ROS1 CSMD1 PLCH1 HYDIN

6.97e-071841758ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 ZAN OBSCN GRIK3 ROS1 CSMD1 PLCH1 HYDIN

6.97e-0718417582b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Aerocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LIN28B ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 KDR ITM2A

7.26e-0718517587b3d30a54bec66ca6b0209c86448f4fff97ed75c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOJ ZNF366 POLA1 DOCK9 RAPGEF4 PLXND1 SPTBN5 KDR

7.87e-07187175835c382c0aabd46906113e5db30ea24bb8e658899
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

EPPK1 DOCK9 GART BTBD9 DNAH14 ROS1 PLCH1 CADPS2

8.19e-071881758ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RHOJ ZNF366 DOCK9 RAPGEF4 AFDN KDR CADPS2 ITM2A

8.53e-071891758fe49852ba15f948b384d6b4c258927c70b741357
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ DOCK9 RAPGEF4 SNRK IGF2BP2 AFDN KDR ITM2A

9.23e-071911758a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 KDR

9.98e-071931758e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ ZNF366 DOCK9 RAPGEF4 SNRK ITGA5 KDR

9.98e-071931758af5108260783e69a7d67896c5bf64f862525926d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK9 RAPGEF4 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

9.98e-071931758a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ DOCK9 RAPGEF4 SNRK IGF2BP2 AFDN KDR

1.04e-0619417580b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ DOCK9 RAPGEF4 SNRK ITGA5 IGF2BP2 AFDN KDR

1.04e-06194175858f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RHOJ DOCK9 RAPGEF4 SNRK ITGA5 IGF2BP2 AFDN KDR

1.04e-061941758bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RNF213 TLR7 IFIT1 SAMD9L TRAFD1 LPIN2 GMPR DDX60L

1.08e-061951758b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK PLXND1 ITGA5 KDR

1.12e-061961758b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

RHOJ ZNF366 DOCK9 RAPGEF4 PON2 SNRK KDR CADPS2

1.16e-0619717587e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF366 DOCK9 SNRK PLXND1 ITGA5 SPTBN5 OIT3 KDR

1.16e-061971758b18f2c14d6720f6ae8520c0800356f4a57393ad3
ToppCellASK452-Endothelial-Endothelium|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

RHOJ DOCK9 RAPGEF4 SNRK ITGA5 IFIT1 KDR ITM2A

1.21e-061981758e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

BCLAF1 RNF213 APLP2 IFIT1 SAMD9L DDX60L DYNC1H1 SMAD7

1.21e-06198175861ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

RHOJ ZNF366 DOCK9 RAPGEF4 SNRK KDR CSMD1 CADPS2

1.26e-061991758793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GCNT3 HMBS AK9 IFIT1 SLC4A1 EYS UBE2O LPIN2

1.26e-0619917586c174dbcc25b980f10a3d1dfe39e613acac73bb6
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GCNT3 HMBS AK9 IFIT1 SLC4A1 EYS UBE2O LPIN2

1.26e-061991758284ee9632413f6404fc0b0c7c393ad813db834f2
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BCLAF1 RNF213 IFIT1 CEP350 SETD2 SAMD9L DDX60L DYNC1H1

1.30e-06200175812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB ZNF366 DOCK9 SNRK IGF2BP2 AFDN KDR ITM2A

1.30e-062001758f15fffefe372005c33e31845982e2d2714ac26af
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZNF366 DOCK9 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

1.30e-06200175858a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK9 RNF213 SNRK IFIT1 SAMD9L KDR ITM2A DYNC1H1

1.30e-062001758be55cef682ba87250dad97689332c8820b3a7420
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GCNT3 HMBS AK9 IFIT1 SLC4A1 UBE2O LPIN2 GMPR

1.30e-062001758f99e214eb680fd82a33f2b1524fbfca265d1cc42
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

DOCK9 RNF213 SNRK IFIT1 IGF2BP2 AFDN KDR ITM2A

1.30e-062001758432384faeade8e609154fab3d96c955a8ec868dd
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GCNT3 HMBS AK9 IFIT1 SLC4A1 UBE2O LPIN2 GMPR

1.30e-062001758d85074b362b11e5a523a5325d203a61aa2759a7a
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

RHOJ ZNF366 RAPGEF4 PLXND1 ITGA5 CNTN5 KDR

3.38e-0616017570d4880f85565d8c540c94a8f8109147b3029279a
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA7 PTCHD1 OIT3 VANGL1 LPIN2 XXYLT1 THAP6

4.31e-06166175735db3022c33d6f8bb6587d9eec89a7cccb70271a
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST10 PCDHGB6 HMBS SLC4A1 UBE2O ZNF341 VANGL1

4.66e-06168175717fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST10 PCDHGB6 HMBS SLC4A1 UBE2O ZNF341 VANGL1

4.66e-061681757a61b39884851384cffd430079040546d125b2b40
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF19 ADH7 EFHC1 OSBPL6 FLRT3 ITM2A PADI1

5.87e-06174175746838b4bb9b4d8ce5e1c608a700e7f393bc52658
ToppCelldroplet-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF19 ADH7 EFHC1 OSBPL6 FLRT3 ITM2A PADI1

5.87e-061741757103594eeb600eb5bc9cbf09a65b286b3a3a18cdc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LIN28B CCDC168 DNAH14 CNTN5 ROS1 PLCH1 CADPS2

5.87e-061741757ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RNF213 IFIT1 SAMD9L DAPP1 LPIN2 DDX60L L3MBTL3

7.06e-061791757af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOJ ZNF366 DOCK9 RAPGEF4 PLXND1 ITGA5 KDR

7.33e-06180175716728b9a1c52097e3a460534be71a476ecc54f0f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK9 RAPGEF4 SNRK IFIT1 AFDN KDR ITM2A

7.33e-06180175730cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TLR7 IFIT1 SAMD9L TRAFD1 LPIN2 GMPR DDX60L

8.16e-061831757dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RHOJ ZNF366 POLA1 RAPGEF4 PLXND1 ITGA5 KDR

8.45e-061841757688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

CARMIL2 OBSCN CCDC168 OSBPL6 VWA3B CSMD1

8.84e-0612217562aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBS AK9 IFIT1 SLC4A1 UBE2O LPIN2 GMPR

9.07e-061861757e5014443e9d6e25943308483e20d48b776ae5373
ToppCellLPS_only-Hematopoietic_Meg-Ery-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBS AK9 IFIT1 SLC4A1 UBE2O LPIN2 GMPR

9.07e-061861757affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCellLPS_only-Hematopoietic_Meg-Ery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBS AK9 IFIT1 SLC4A1 UBE2O LPIN2 GMPR

9.07e-06186175740d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK9 BTBD9 DNAH14 TKT ROS1 PLCH1 CADPS2

9.07e-061861757acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ DOCK9 RAPGEF4 SNRK ITGA5 KDR

9.39e-061871757dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RNF213 IFIT1 SAMD9L DAPP1 LPIN2 DDX60L L3MBTL3

9.73e-0618817576f8946d4710f6e32c937213f99b790b098b8819c
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB RAPGEF4 SNRK APLP2 IFIT1 AFDN KDR

1.04e-05190175738a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB RAPGEF4 SNRK APLP2 IFIT1 AFDN KDR

1.04e-051901757bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB RAPGEF4 SNRK APLP2 IFIT1 AFDN KDR

1.04e-051901757d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB DOCK9 RAPGEF4 SNRK IFIT1 AFDN KDR

1.12e-0519217578f20d3511dcb44445592b17d005a53da0052ae56
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB RHOJ HSPA4L DOCK9 RAPGEF4 ITGA5 KDR

1.12e-0519217570aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB DOCK9 RAPGEF4 SNRK IFIT1 AFDN KDR

1.12e-0519217570986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A ZNF366 DOCK9 RAPGEF4 SNRK APLP2 SCN7A

1.12e-0519217574bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK9 PON2 BTBD9 DNAH14 ROS1 PLCH1 CADPS2

1.12e-051921757fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB DOCK9 RAPGEF4 SNRK IFIT1 AFDN KDR

1.12e-051921757b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

DNAJB1 FRAS1 VPS54 IGF2BP2 AFDN CHD6 PPP6R3

1.15e-051931757e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOJ ZNF366 RAPGEF4 SNRK PLXND1 ITGA5 ITM2A

1.19e-051941757cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
Drugclinoptilolite

RHOJ RB1 BCLAF1 CAPN3 TKT

2.70e-07191755CID006336554
DiseaseAdenocarcinoma of lung (disorder)

GART INSRR ARHGAP35 SGK2 NEK1 LATS1 KDR ROS1

2.74e-052061708C0152013
Diseasecolorectal cancer (is_implicated_in)

SETD2 NF2 CHEK2 KDR TRPV3 SMAD7

7.44e-051211706DOID:9256 (is_implicated_in)
DiseaseBone osteosarcoma

RB1 CHEK2

9.86e-0531702cv:C0585442
DiseaseOSTEOGENIC SARCOMA

RB1 CHEK2

9.86e-0531702259500
Diseaselymphocyte count

DOCK2 FLNB FRAS1 EPPK1 HTR1D CARMIL2 ZAN PCDHGB6 RB1 INSRR PLXND1 HORMAD1 SLC4A1 SETD2 IGF2BP2 UBE2O CNTN5 CHEK2 DZIP3 DDX60L L3MBTL3

1.11e-04146417021EFO_0004587
Diseasemalignant pleural mesothelioma (is_implicated_in)

SETD2 NF2

1.96e-0441702DOID:7474 (is_implicated_in)
Diseaseseminoma (is_marker_for)

RB1 HMBS CHEK2

2.67e-04221703DOID:4440 (is_marker_for)
DiseaseQRS duration, response to sulfonylurea

DOCK9 MDN1 CSMD1

3.06e-04231703EFO_0005055, EFO_0007922
Diseaseresponse to platinum based chemotherapy, cytotoxicity measurement

FRAS1 EYS

3.26e-0451702EFO_0004647, EFO_0006952
Diseaseairway responsiveness measurement

DZIP3 SCUBE3 CSMD1

3.48e-04241703EFO_0006897
DiseaseMalignant neoplasm of breast

FLNB PCDHGB6 RB1 ZNF366 SMARCAL1 OBSCN ELP1 GRIK3 COG3 TTC3 SETD2 NF2 FARP1 CHEK2 KDR L3MBTL3

5.06e-04107417016C0006142
Diseaseembryonal carcinoma (is_marker_for)

RB1 CHEK2

6.80e-0471702DOID:3308 (is_marker_for)
Diseaseobsolete_red blood cell distribution width

CARMIL2 ZNF366 AK9 FREM3 SLC4A1 IGF2BP2 PTPA CNTN5 EIF3L VPS13A DAPP1 LPIN2 CHEK2 AFDN GMPR CLUH PPP6R3 SMAD7

8.06e-04134717018EFO_0005192
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

PON2 TXNRD1 NEK1

8.24e-04321703DOID:332 (is_implicated_in)
DiseaseLarge cell carcinoma of lung

NEK1 LATS1 ROS1

8.24e-04321703C0345958
Diseaseeating disorder

FLNB ADH7 CSMD1

8.24e-04321703EFO_0005203
Diseaseintellectual disability (implicated_via_orthology)

RB1 CAPN3 ITGA5 BOD1L2

9.40e-04751704DOID:1059 (implicated_via_orthology)
DiseaseDisproportionate short stature

FLNB SMARCAL1 CUL7 NEK1

1.04e-03771704C0878659
Diseaseresponse to carboplatin, response to antineoplastic agent

FLNB CSMD1

1.44e-03101702GO_0097327, GO_0097328
DiseaseMoyamoya disease

DOCK9 RAPGEF4 RNF213

1.59e-03401703MONDO_0016820
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CUL7 RYR1 SETD2 NF2 KDR

1.70e-031481705C0279702
Diseasegastrointestinal stromal tumor (is_implicated_in)

SETD2 NF2

1.75e-03111702DOID:9253 (is_implicated_in)
Diseasefibrinogen measurement, tissue plasminogen activator measurement

CAPN3 PLXND1 TRAFD1

2.23e-03451703EFO_0004623, EFO_0004791
Diseasehemolysis

SLC4A1 EYS CNTN5

2.53e-03471703EFO_0009473
DiseaseNeuroblastoma

LIN28B CHEK2 CHD6

2.53e-03471703C0027819
DiseaseColorectal Carcinoma

CALCOCO2 ABCB5 OBSCN GRIK3 TXNRD1 VPS13A CHEK2 KDR DSEL ACSL5 SMAD7

2.61e-0370217011C0009402
Diseasehypoxanthine mesurement

XXYLT1 GMPR

2.87e-03141702EFO_0010500
Diseasetotal brain volume change measurement

ADH7 CNTN5

2.87e-03141702EFO_0021504
Diseasemalignant pleural mesothelioma (is_marker_for)

SETD2 NF2

2.87e-03141702DOID:7474 (is_marker_for)
Diseasenon-alcoholic fatty liver disease, cirrhosis of liver

FARP1 CNTN5 DDX60L

3.56e-03531703EFO_0001422, EFO_0003095
Diseaseosteosarcoma (is_implicated_in)

RB1 CHEK2

3.76e-03161702DOID:3347 (is_implicated_in)
Diseaseresponse to acetylsalicylate

SETD2 KIF9

3.76e-03161702GO_1903492
DiseaseSmall cell carcinoma of lung

RB1 BCLAF1 GRIK3

3.76e-03541703C0149925
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

CAPN3 ADH7 TRAFD1

4.16e-03561703EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

SETD2 AP2M1

4.24e-03171702DOID:0060307 (is_implicated_in)
DiseaseDrug habituation

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0013170
DiseaseDrug abuse

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0013146
DiseasePrescription Drug Abuse

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C4316881
DiseaseSubstance-Related Disorders

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0236969
DiseaseDrug Use Disorders

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0013222
DiseaseDrug Dependence

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C1510472
DiseaseSubstance Dependence

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0038580
DiseaseSubstance Use Disorders

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

ZNF366 FARP1 CSMD1 CADPS2

4.48e-031151704C0029231
DiseaseSubstance abuse problem

ZNF366 FARP1 CSMD1 CADPS2

4.62e-031161704C0740858
DiseasePROSTATE CANCER, HEREDITARY, 1

DOCK2 HAUS6 CHEK2

5.05e-03601703C4722327
DiseaseDiGeorge syndrome (implicated_via_orthology)

ZNF366 PLXND1

5.29e-03191702DOID:11198 (implicated_via_orthology)
DiseaseColorectal Neoplasms

CALCOCO2 ABCB5 TXNRD1 CHEK2 KDR SMAD7

5.53e-032771706C0009404

Protein segments in the cluster

PeptideGeneStartEntry
ILSEEFIDPKSHKFV

VANGL1

501

Q8TAA9
KFDLDQLITHVLPFK

ADH7

351

P40394
VFKFVDPSQDHALAK

AFDN

496

P55196
PSIKHKDALVEFGSF

CA5B

201

Q9Y2D0
VKVNPDFVIALIFKS

CSMD1

1481

Q96PZ7
TFSKLIKIFQDHPLQ

SLC4A1

536

P02730
EEKNISFFILHFEPV

BTLA

91

Q7Z6A9
AFHIFQVIDKKPSID

ABCB5

356

Q2M3G0
HEFLVAQKEAAVPAL

BOD1L2

141

Q8IYS8
QLAQHVAAAIKKVFP

CARMIL2

106

Q6F5E8
AFKHPKEVLDVSLLF

FBXW10

611

Q5XX13
NEPISKEEFVIHTIF

FLRT3

601

Q9NZU0
EVVAPFKHFNKLREF

ANKRD13C

471

Q8N6S4
FPNILKEIKHFDADV

ANGEL2

201

Q5VTE6
NHPCIIKIKNFFDAE

CHEK2

281

O96017
VFVLKDKPHNIFKRD

DNAJB1

236

P25685
KQHILPAEKEVTEFY

ACAD11

391

Q709F0
KIEVHFPFTVTAAKG

CNTN5

301

O94779
ISVHKFFNLLKEIDT

RB1

126

P06400
TKLLAVDFPEHFVKS

RAG1

276

P15918
TDLKKHPEREFQLFK

RBM44

571

Q6ZP01
DKLFDSHKLVLNVPF

PADI1

191

Q9ULC6
SKKFNIVEPVLAFLH

OPHN1

191

O60890
PQFDKKEIHLEIFES

PCDHGB6

131

Q9Y5F9
EKAVAVPAKLFKEHQ

L3MBTL3

241

Q96JM7
EVRKFLALKQTPDFH

NOL11

416

Q9H8H0
KIHFEGKIFPLISQA

ARHGEF19

576

Q8IW93
AFKHPKEVLDVSLLF

FBXW10B

611

O95170
DVLLVPEKCQFFHKE

APLP2

141

Q06481
QIEGIKIQPFHFIKD

FBXO22

181

Q8NEZ5
KQFPLHEKDFADILV

MDN1

3576

Q9NU22
VLKFSPGVDHIFFKV

FRAS1

3096

Q86XX4
KLEKDTADVVHPFFL

HAUS2

71

Q9NVX0
VILDKEHRPVEKFVF

MAD2L2

86

Q9UI95
LELPFLKFVLEKEHN

EYS

2156

Q5T1H1
DVDKSVQPEPFFHKV

NEK1

976

Q96PY6
ADEIKAHPFFKTIDF

LATS1

1001

O95835
TLHEVLEKVFKSFRP

MTURN

81

Q8N3F0
HKEPFLQQLKVFSDE

EIF3L

436

Q9Y262
ILVFDPKQEEVSFFH

KIF18A

41

Q8NI77
QILKPENKFHVKFAD

KCNT1

471

Q5JUK3
LDIPVDVFVHQSKLF

LIN28B

56

Q6ZN17
SLFDFLHPKDVAKVK

ARNTL2

226

Q8WYA1
SHLVKEFNVGKSFPL

DDX60L

401

Q5H9U9
KPEHGNSVKFITIFE

FSIP2

6831

Q5CZC0
HVVKIFFAGDTIPKS

FLNB

426

O75369
LKNPQFVFDIDKTDH

PLXND1

1776

Q9Y4D7
FQVPVFKFVGKDHKE

OIT3

476

Q8WWZ8
LKLPFLKAAHVSEQF

CUL7

1206

Q14999
FAFEKLIQFKSVIHI

ABCC11

241

Q96J66
FLESKPKQEFLLNLH

DEPDC1

456

Q5TB30
LPTSFVKEIHDFVLE

PI4KA

391

P42356
GHFTLPFLKDEVKVN

ELP1

276

O95163
LFPLKFVQLFVHDKS

GARIN5A

181

Q6IPT2
VFEPKLNYSDHDVIK

AP2M1

406

Q96CW1
FFNPKEEVKLEAHIR

IGF2BP2

501

Q9Y6M1
KVHAFVRVKPTDDFA

KIF9

6

Q9HAQ2
EVEAVKVHSFPTLKF

P4HB

431

P07237
PIVLAIEDFHKQSFF

CYFIP2

611

Q96F07
LEHIPKFFKKVIDAN

OSBPL6

891

Q9BZF3
VFDEAILTIFHPKKK

RHOJ

186

Q9H4E5
KGVVPHIKKFLQEDF

DZIP3

66

Q86Y13
FFLAKVHKIDPDIIV

POLA1

621

P09884
VSKEEPVTFHFLAKF

NF2

86

P35240
KVFVSKVEAVIHPQF

NUTM1

421

Q86Y26
FHLDVKEPKVVFAKD

OBSCN

971

Q5VST9
SFQLHITEPKAVFAK

OBSCN

1246

Q5VST9
PAEEAHFINTKQLKF

OBSCN

6726

Q5VST9
VNHPEFKNTVEIFKF

PON2

131

Q15165
VPHLRDTKKTIQFDF

ITGA5

751

P08648
IHPEKKAEIVFQFTP

HYDIN

4036

Q4G0P3
QGIFPKSFIHIKEVT

DOCK2

56

Q92608
IQVTHVIPFFDEKEL

DOCK9

1866

Q9BZ29
FPKDVTHFLKNSIER

CYP3A43

241

Q9HB55
HKESFLAPVFTKDEQ

CHD6

2161

Q8TD26
VVVKFVVKFFPPDHT

FARP1

111

Q9Y4F1
EQIAPFHTEFTIKEI

COG3

621

Q96JB2
KEQEFRSIFDHIKLP

BCLAF1

581

Q9NYF8
SLKDFVKHFANQPLI

DAPP1

101

Q9UN19
EHFKAERKFIQFPLS

GCNT3

111

O95395
FQKEAEKFLPLFGHI

CEP350

1031

Q5VT06
SQLAQFVHEVKKSPF

DDX12P

256

Q92771
PLFFNHVKIKLADSA

HTR1D

271

P28221
LFIDKHPVDISDVFI

ADGRF2

276

Q8IZF7
GLKTFEQVKAIFLHP

ACSL5

631

Q9ULC5
DKIFPATEKQIFEDH

CALCOCO2

426

Q13137
GKFHKHLQEIFVPLV

CADPS2

921

Q86UW7
SFKREKVSPKEVHEF

DNAH14

2756

Q0VDD8
KIRHFPNEFIVETKI

ITM2A

246

O43736
IFHFESAVEKKPTFE

IFIT1

326

P09914
KKFENFLHNAITIPI

INSRR

711

P14616
IPAHVAFDKKVLKFD

EFHC1

86

Q5JVL4
TAEVLANKIVPFFKL

DYNC1H1

2061

Q14204
FVETFNIKPQDLHKC

HAUS6

151

Q7Z4H7
NVGEVSTPFHIFKVK

HORMAD1

211

Q86X24
GITEFHVLNSKKPFD

CCDC168

666

Q8NDH2
FSKIHPLQIENKKEF

CCDC168

2726

Q8NDH2
DAVVFHPKFVGKTLE

HMBS

121

P08397
EHFVEFVKLVRAKFP

GMPR

136

P36959
ITHVREKAIDFSKPF

GRIK3

521

Q13003
GDVTFVVEKKRFPAH

BTBD9

36

Q96Q07
FPIIGVKEKTFEQLH

CAPN3

51

P20807
KDESPAKAEFFQHLI

SEC24B

1231

O95487
KKLIKAFFEVLAHPQ

SCUBE3

946

Q8IX30
VEKSPHEQEIKFFAK

RYR1

2986

P21817
KFEDIVHFPQKTTER

DSEL

1126

Q8IZU8
KIKLEPHEVDQFLNF

CREB3L2

176

Q70SY1
FAETVKVFLKHPSVK

INVS

301

Q9Y283
EDFTIFIKNHIRFPK

P2RX5

186

Q93086
KDFVTKVEAVIHPQF

NUTM2D

501

Q5VT03
DVVAVFPKTEKLFHI

RPP30

101

P78346
NIEPLISAFHKVEKF

GPRASP1

1361

Q5JY77
DEQPKLFAHEFKVLE

FREM3

1191

P0C091
LDQVAHKLPFAAKAV

MRPL16

176

Q9NX20
DTKHFCPVVLKENFI

AK9

931

Q5TCS8
LFELFHQAGPVIKVK

RBM7

26

Q9Y580
FSFKEHVDKAIALQP

RMDN3

346

Q96TC7
TRLKEVKAFEKFHPN

RAPGEF4

36

Q8WZA2
HVQKEIVKEFFIRGP

TRMT2B

256

Q96GJ1
ADFLEIKNHVFFSPI

SGK2

281

Q9HBY8
CKKEIPVFNFTIHEI

TRAFD1

16

O14545
EFFDVLPVHKFQKTP

NDUFAF7

216

Q7L592
DFPEKAKDIFIEAHL

MRPL45

136

Q9BRJ2
PQFSHFQEDIIFSKK

PTCHD1

621

Q96NR3
LQLTPFFHKENELSK

SAMD9L

1211

Q8IVG5
VIHDFLFSLKESPEK

FAF2

386

Q96CS3
VLLPEGHKKSFFQAA

EPPK1

291

P58107
FFIDFPHIEEQQKKI

TENT5D

266

Q8NEK8
TPFKVVIIDESHFLK

SMARCAL1

541

Q9NZC9
PIKTVFADVAFVKKH

THNSL2

201

Q86YJ6
KKKPEVFNFSAIHLI

SDAD1

276

Q9NVU7
KGLTFHVFPTDENIK

THAP6

21

Q8TBB0
IPTHLFTFIQFKKDL

RO60

121

P10155
KILNEPLKHSDFFNV

MRPS2

61

Q9Y399
PLKHSDFFNVKELFS

MRPS2

66

Q9Y399
LEIFHPFFKDVVEKK

ARHGAP35

931

Q9NRY4
VHRDLKPENVVFFEK

SNRK

136

Q9NRH2
KPLLKHQAFEAEVQA

SPTBN5

2186

Q9NRC6
PSHIKENIQVFDFEL

AKR1E2

271

Q96JD6
EEKVRIAAKFIIHAP

CAPZA2

11

P47755
ISAFKDKFVHNPRFE

CHST10

196

O43529
FTEEDVLNIFPVVKH

CLUH

956

O75153
EDVFAALHLKKPVAI

RECQL5

201

O94762
EEHGIKFIRQFVPIK

TXNRD1

391

Q16881
LSVFLKKQEESQFHP

RNF213

3586

Q63HN8
TVFFESLERQLKHPK

UBA6

296

A0AVT1
LVHKVFPGFSIKAFD

SMAD7

356

O15105
AQTFPKLDTFLEHIK

ZNF341

481

Q9BYN7
HAREFGKIINFKTPE

VPS13A

3141

Q96RL7
VAPHLKETLNKNFFD

VPS35L

346

Q7Z3J2
TFSEIFKKEHPDRFI

TKT

346

P29401
VITFHKKEPFELEAF

HSPA4L

431

O95757
EKFPVIQHFKFGSLL

PTPA

336

Q15257
FLHEVPAASEEIFKI

VPS16

326

Q9H269
VLEFAPSNHSFKKIE

UBE2O

931

Q9C0C9
KKPFNSIIEHLSVVF

TTC3

1841

P53804
GHNDPADFVRKIIFK

MTERF1

226

Q99551
LDKHSELFSNKQLPF

SPATA7

226

Q9P0W8
DKHFTEFVPLRTKAK

ATP6V1A

466

P38606
IVRDFFPTVFVKEKH

PROKR2

296

Q8NFJ6
KPKHENGVLTKFEIF

ROS1

1071

P08922
ELPEHLKIKEDNFFQ

RFK

131

Q969G6
VFKELKSFNLSPLHN

TLR7

381

Q9NYK1
VKLAEHKIFPAALQL

GART

976

P22102
INKHAFVKNEFPVIL

PLCH1

376

Q4KWH8
FFLHKGTEKNPEISF

SETD2

1131

Q9BYW2
AFVQKPEFIIHQKTH

ZNF585A

166

Q6P3V2
LVLAKHFEPQDAKAV

UBL4B

96

Q8N7F7
AKQVAFHIPFEVVEK

ZSWIM8

81

A7E2V4
EDVHFDLAVKKTPSF

ZNF366

11

Q8N895
PTKKSAHFFLEIEGF

TRPV3

36

Q8NET8
VPFTKESFELIKQHI

SCN7A

11

Q01118
KKNSTFVRVHEKPFV

KDR

316

P35968
DKHVVSKVFDEVFPL

VWA3B

881

Q502W6
KKKNTHSLFVFIIPE

SOHLH2

91

Q9NX45
PEQIVDFLKKKHDFV

PPP6R3

136

Q5H9R7
SDVFFKIEVDPSKHI

VPS54

16

Q9P1Q0
FHDVAVLTDKLFPIV

XXYLT1

171

Q8NBI6
ALPFFKISAKHEKEE

ZAN

1966

Q9Y493
DEPLIHVFAKNLVAF

PSMG3

71

Q9BT73
FSAFHREVIEKKPEK

LPIN2

771

Q92539