Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.52e-07181615GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH2 DNAAF5 DNAH17 DNAH8 DNAH9

4.73e-07371616GO:0045505
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.71e-06281615GO:0051959
GeneOntologyMolecularFunctiondystroglycan binding

CLASP1 DAG1 CLASP2

1.07e-04121613GO:0002162
GeneOntologyMolecularFunctionglycerol kinase activity

GK GK2

1.93e-0431612GO:0004370
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.54e-04701615GO:0003777
GeneOntologyBiologicalProcesspositive regulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP1 DAG1 CLASP2

4.28e-0651573GO:1904261
GeneOntologyBiologicalProcessregulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP1 DAG1 CLASP2

4.28e-0651573GO:1904259
GeneOntologyBiologicalProcessbasement membrane assembly involved in embryonic body morphogenesis

CLASP1 DAG1 CLASP2

4.28e-0651573GO:2001197
GeneOntologyBiologicalProcesscilium movement

DNAH10 DNAH2 TAC4 DNAAF5 CFAP54 GK2 DNAH17 CFAP206 DNAH8 DNAH9

3.25e-0526115710GO:0003341
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH10 DNAH2 TAC4 CFAP54 GK2 DNAH17 CFAP206 DNAH8 DNAH9

3.41e-052101579GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH10 DNAH2 TAC4 CFAP54 GK2 DNAH17 CFAP206 DNAH8 DNAH9

4.10e-052151579GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH10 DNAH2 TAC4 CFAP54 GK2 DNAH17 CFAP206 DNAH8 DNAH9

4.10e-052151579GO:0001539
GeneOntologyBiologicalProcessglycerol-3-phosphate metabolic process

GPAT3 GK GK2

4.99e-05101573GO:0006072
GeneOntologyBiologicalProcessregulation of basement membrane organization

CLASP1 DAG1 CLASP2

6.83e-05111573GO:0110011
GeneOntologyBiologicalProcessalditol phosphate metabolic process

GPAT3 GK GK2

9.05e-05121573GO:0052646
GeneOntologyBiologicalProcessbasement membrane assembly

CLASP1 DAG1 CLASP2

9.05e-05121573GO:0070831
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix organization

CLASP1 DAG1 CLASP2 COLGALT1

1.25e-04341574GO:1903055
GeneOntologyBiologicalProcessglycerol-3-phosphate biosynthetic process

GK GK2

1.72e-0431572GO:0046167
GeneOntologyBiologicalProcesspositive regulation of extracellular matrix assembly

CLASP1 DAG1 CLASP2

1.84e-04151573GO:1901203
GeneOntologyBiologicalProcessembryonic body morphogenesis

CLASP1 DAG1 CLASP2

1.84e-04151573GO:0010172
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

SNX17 HSD3B7 MOXD1 GK GK2

2.37e-04731575GO:1901616
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAH2 DNAAF5 DNAH17 DNAH8

2.63e-04411574GO:0070286
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway

HLA-E HLA-F

3.42e-0441572GO:0002488
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent

HLA-E HLA-F

3.42e-0441572GO:0002489
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

1.27e-06251635GO:0005858
GeneOntologyCellularComponentdynein complex

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

6.30e-05541635GO:0030286
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH8 DNAH9

9.72e-05121633GO:0036157
GeneOntologyCellularComponentcis-Golgi network membrane

HLA-E HLA-F PMEL

2.92e-04171633GO:0033106
MousePhenohypochlorhydria

TRIM73 TRIM50 TRIM74

2.56e-0571283MP:0008001
MousePhenoabnormal motile cilium morphology

DNAH10 TRIP6 DNAH2 OCA2 DNAAF5 CFAP54 GK GK2 DNAH17 CFAP206 ROS1 DNAH8 DNAH9

3.44e-0537012813MP:0013206
MousePhenoabnormal stomach mucosa morphology

TRIM73 VSIG1 TRIM50 SEC23B CNTN1 TRIM74

7.30e-05771286MP:0010792
MousePhenocerebral infarct

SPTA1 SPTB

8.32e-0521282MP:0021003
MousePhenoabnormal stomach wall morphology

TRIM73 VSIG1 TRIM50 SEC23B CNTN1 TRIM74

9.05e-05801286MP:0010783
MousePhenoabsent sperm flagellum

DNAH10 DNAH2 CFAP54 CFAP206 DNAH8

9.06e-05501285MP:0008545
MousePhenolow mean erythrocyte cell number

SPTA1 SPTB KMT2E

1.55e-04121283MP:0002594
MousePhenokinked sperm flagellum

DNAH2 GK GK2 CFAP206 DNAH8

1.56e-04561285MP:0009237
MousePhenoabnormal cilium morphology

DNAH10 TRIP6 DNAH2 OCA2 DNAAF5 CFAP54 GK GK2 DNAH17 CFAP206 ROS1 DNAH8 DNAH9

1.68e-0443312813MP:0013202
MousePhenoabnormal spleen iron level

SPTA1 SLC40A1 LTF EPB42

1.98e-04321284MP:0008739
MousePhenohypochromic microcytic anemia

SPTA1 PICALM SLC40A1

2.01e-04131283MP:0008388
MousePhenospherocytosis

SPTA1 SPTB EPB42

2.01e-04131283MP:0002812
MousePhenoabnormal ependyma motile cilium morphology

TRIP6 DNAAF5 CFAP54 DNAH9

2.23e-04331284MP:0011059
MousePhenoabnormal gastric gland morphology

TRIM73 TRIM50 SEC23B TRIM74

2.51e-04341284MP:0003892
MousePhenoshort sperm flagellum

DNAH10 DNAH2 CFAP54 CFAP206 DNAH8

2.73e-04631285MP:0009239
MousePhenoabnormal digestive secretion

TRIM73 CHRM5 TRIM50 TRIM74

2.82e-04351284MP:0000501
MousePhenoabnormal kidney iron level

SPTA1 SPTB SLC40A1

3.15e-04151283MP:0008742
MousePhenoincreased kidney iron level

SPTA1 SPTB SLC40A1

3.15e-04151283MP:0010375
MousePhenoabnormal sperm flagellum morphology

DNAH10 DNAH2 OCA2 CFAP54 GK GK2 DNAH17 CFAP206 ROS1 DNAH8

3.81e-0429512810MP:0008892
MousePhenodecreased spleen iron level

SPTA1 SLC40A1 LTF

4.64e-04171283MP:0008808
MousePhenoincreased stomach pH

TRIM73 TRIM50 TRIM74

4.64e-04171283MP:0008006
DomainDHC_N1

DNAH10 DNAH2 DNAH8 DNAH9

3.11e-0781554PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH2 DNAH8 DNAH9

3.11e-0781554IPR013594
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554IPR013602
DomainDHC_N2

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554PF08393
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554IPR011704
DomainMT

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554PF12777
DomainAAA_8

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554PF12780
DomainAAA_5

DNAH10 DNAH2 DNAH8 DNAH9

4.28e-06141554PF07728
DomainDHC_fam

DNAH10 DNAH2 DNAH8 DNAH9

5.80e-06151554IPR026983
DomainDynein_heavy

DNAH10 DNAH2 DNAH8 DNAH9

5.80e-06151554PF03028
DomainDynein_heavy_dom

DNAH10 DNAH2 DNAH8 DNAH9

5.80e-06151554IPR004273
DomainDUF3669_Znf

ZNF212 ZNF398 ZNF282

1.10e-0561553IPR022137
DomainDUF3669

ZNF212 ZNF398 ZNF282

1.10e-0561553PF12417
DomainIg-like_fold

MPL IL10RA FN1 MYCBP2 HLA-E HLA-F DAG1 VSIG1 IL18RAP LRIT3 AREL1 PTPRH ROS1 SDK1 PLXNA2 EPB42 CNTN1

8.14e-0570615517IPR013783
Domain-

SEMA4F LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1 PLXNA2

1.08e-04333155112.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA4F LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1 PLXNA2

1.14e-0433515511IPR015943
Domain-

MPL IL10RA FN1 MYCBP2 HLA-E HLA-F DAG1 VSIG1 IL18RAP LRIT3 AREL1 ROS1 SDK1 PLXNA2 EPB42 CNTN1

1.30e-04663155162.60.40.10
DomainGPS

ADGRV1 PKD1L2 ADGRG4 ADGRF4

1.96e-04351554PF01825
DomainSV2

SV2A SV2C

2.04e-0431552IPR022308
DomainCarb_kinase_FGGY_CS

GK GK2

2.04e-0431552IPR018483
DomainPentapeptide_4

SV2A SV2C

2.04e-0431552PF13599
DomainGPS

ADGRV1 PKD1L2 ADGRG4 ADGRF4

2.19e-04361554PS50221
DomainGPS

ADGRV1 PKD1L2 ADGRG4 ADGRF4

2.43e-04371554IPR000203
DomainFN3_dom

MPL IL10RA FN1 LRIT3 PTPRH ROS1 SDK1 CNTN1

3.63e-042091558IPR003961
Domain5peptide_repeat

SV2A SV2C

4.06e-0441552IPR001646
DomainCLASP_N

CLASP1 CLASP2

4.06e-0441552PF12348
DomainCLASP_N_dom

CLASP1 CLASP2

4.06e-0441552IPR024395
DomainHoxA13_N

HOXA13 HOXB13

4.06e-0441552PF12284
DomainGlycerol_kin

GK GK2

4.06e-0441552IPR005999
DomainHoxA13_N

HOXA13 HOXB13

4.06e-0441552IPR022067
DomainWD40_repeat_CS

LRWD1 COPA WDR59 TBC1D31 EML5 KCTD3 WDR90

4.44e-041641557IPR019775
DomainWD40_repeat

LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

4.56e-042721559IPR001680
DomainWD_REPEATS_1

LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

5.34e-042781559PS00678
DomainWD_REPEATS_2

LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

5.48e-042791559PS50082
DomainWD_REPEATS_REGION

LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

5.48e-042791559PS50294
DomainFGGY_KINASES_1

GK GK2

6.73e-0451552PS00933
DomainCarb_kinase_FGGY_C

GK GK2

6.73e-0451552IPR018485
DomainFGGY_KINASES_2

GK GK2

6.73e-0451552PS00445
DomainWD40_repeat_dom

LRWD1 COPA VPS8 WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

8.55e-042971559IPR017986
DomainSpectrin

SYNE1 SPTA1 SPTB

8.79e-04231553PF00435
DomainFN3

MPL FN1 LRIT3 PTPRH ROS1 SDK1 CNTN1

9.06e-041851557SM00060
DomainQuinoprotein_ADH-like_supfam

VPS8 EML5 WDR90 EML1

9.74e-04531554IPR011047
DomainMHC_I_a_C

HLA-E HLA-F

1.00e-0361552IPR010579
DomainCarb_kinase_FGGY_N

GK GK2

1.00e-0361552IPR018484
DomainHELP

EML5 EML1

1.00e-0361552PF03451
DomainFGGY_C

GK GK2

1.00e-0361552PF02782
DomainMHC_I_C

HLA-E HLA-F

1.00e-0361552PF06623
DomainHELP

EML5 EML1

1.00e-0361552IPR005108
DomainGalactose-bd-like

MYCBP2 NTN3 LAMC3 F8 HECTD1

1.12e-03941555IPR008979
DomainFN3

MPL FN1 LRIT3 PTPRH ROS1 SDK1 CNTN1

1.38e-031991557PS50853
DomainCarb_kinase_FGGY

GK GK2

1.40e-0371552IPR000577
DomainFGGY_N

GK GK2

1.40e-0371552PF00370
DomainSpectrin_repeat

SYNE1 SPTA1 SPTB

1.75e-03291553IPR002017
DomainWD40

LRWD1 COPA WDR59 TBC1D31 EML5 KCTD3 WDR90 EML1

1.82e-032681558SM00320
DomainSPEC

SYNE1 SPTA1 SPTB

2.33e-03321553SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTA1 SPTB

2.33e-03321553IPR018159
Domainfn3

MPL FN1 PTPRH ROS1 SDK1 CNTN1

2.34e-031621556PF00041
DomainGPS

ADGRV1 PKD1L2 ADGRG4

2.78e-03341553SM00303
Domainzf-RING_UBOX

TRIM73 TRIM50 TRIM74

2.78e-03341553PF13445
DomainZnf-RING_LisH

TRIM73 TRIM50 TRIM74

2.78e-03341553IPR027370
Domain-

MYCBP2 LAMC3 F8 HECTD1

3.19e-037315542.60.120.260
DomainFilamin

MYCBP2 AREL1

3.58e-03111552PF00630
DomainFILAMIN_REPEAT

MYCBP2 AREL1

3.58e-03111552PS50194
DomainDHR-1_domain

DOCK4 DOCK6

3.58e-03111552IPR027007
DomainDHR_2

DOCK4 DOCK6

3.58e-03111552PS51651
DomainDHR_1

DOCK4 DOCK6

3.58e-03111552PS51650
DomainDHR-2

DOCK4 DOCK6

3.58e-03111552PF06920
DomainFilamin/ABP280_rpt

MYCBP2 AREL1

3.58e-03111552IPR001298
DomainFilamin/ABP280_repeat-like

MYCBP2 AREL1

3.58e-03111552IPR017868
DomainDOCK

DOCK4 DOCK6

3.58e-03111552IPR026791
DomainDOCK_C

DOCK4 DOCK6

3.58e-03111552IPR010703
DomainDOCK-C2

DOCK4 DOCK6

3.58e-03111552PF14429
DomainDHR-2

DOCK4 DOCK6

3.58e-03111552IPR027357
DomainGPCR_2_extracellular_dom

ADGRV1 ADGRG4 ADGRF4

4.42e-03401553IPR001879
DomainG_PROTEIN_RECEP_F2_1

ADGRV1 ADGRG4 ADGRF4

4.42e-03401553PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRV1 ADGRG4 ADGRF4

4.42e-03401553PS50227
DomainZF_BBOX

MYCBP2 TRIM73 TRIM50 TRIM74

4.43e-03801554PS50119
Domain-

GALNT1 COLGALT1 UGGT2 GALNT5

4.63e-038115543.90.550.10
DomainZnf_B-box

MYCBP2 TRIM73 TRIM50 TRIM74

4.63e-03811554IPR000315
DomainWD40

LRWD1 COPA WDR59 TBC1D31 EML5 WDR90 EML1

5.95e-032591557PF00400
DomainNucleotide-diphossugar_trans

GALNT1 COLGALT1 UGGT2 GALNT5

6.20e-03881554IPR029044
DomainN2O_reductase_N

VPS8 EML1

6.69e-03151552IPR011045
DomainER_TARGET

COLGALT1 FOXRED2 UGGT2

6.96e-03471553PS00014
DomainHEAT

CLASP1 CLASP2 DNAAF5

7.38e-03481553PF02985
DomainLaminin_N

NTN3 LAMC3

7.61e-03161552IPR008211
DomainLamNT

NTN3 LAMC3

7.61e-03161552SM00136
DomainLAMININ_NTER

NTN3 LAMC3

7.61e-03161552PS51117
DomainLaminin_N

NTN3 LAMC3

7.61e-03161552PF00055
Domain7tm_2

ADGRV1 ADGRG4 ADGRF4

8.26e-03501553PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRV1 ADGRG4 ADGRF4

8.26e-03501553PS00650
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.22e-06271145M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.39e-05431145M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

2.99e-05451145M47670
PathwayKEGG_ECM_RECEPTOR_INTERACTION

FN1 ITGA10 DAG1 LAMC3 SV2A SV2C

5.96e-05841146M7098
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH17 DNAH8 DNAH9

1.69e-087165431178125
Pubmed

Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.

TRIM73 TRIM50 TRIM74

1.05e-073165326196062
Pubmed

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

TRIM73 TRIM50 TRIM74

1.05e-073165322872646
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH2 DNAH17 DNAH8

4.71e-071416549373155
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

AUP1 CISD1 ST7 PIGS SNX17 VPS8 GPAT3 WDR59 ATL1 PTPN13 SV2A DOCK6 STX6

9.59e-075041651334432599
Pubmed

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.

TRIM73 TRIM50 TRIM74

1.04e-065165320049703
Pubmed

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex.

CLASP1 DAG1 CLASP2

1.04e-065165323940118
Pubmed

Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.

TRIM73 TRIM50 TRIM74

1.04e-065165318398435
Pubmed

TRIM50 regulates Beclin 1 proautophagic activity.

TRIM73 TRIM50 TRIM74

2.08e-066165329604308
Pubmed

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

TRIM73 TRIM50 TRIM74

2.08e-066165336178239
Pubmed

A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice.

SPTA1 SPTB EPB42

2.08e-066165327848995
Pubmed

Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.

COLGALT1 FOXRED2 NUP210 UGGT2

2.74e-0621165423097496
Pubmed

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.

TRIM73 TRIM50 TRIM74

3.62e-067165326025256
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

USP53 DPP6 MYCBP2 ST7 SPTB HECTD4 CLASP2 ADGRV1 TSEN2 SLC35F5 DNAAF5 PTPN13 RALGPS1 ANKAR NUP210 SNTG2 TTC17 DOCK6 HECTD1 DAGLA PDZD2

8.45e-0614891652128611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP53 ZNF212 SNX17 HECTD4 ICE1 ADGRV1 NUP205 RALGPS1 HMGXB3 WDR90 DOCK6 DAGLA

9.32e-065291651214621295
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CLASP1 HECTD4 CLASP2 ADGRV1 L3MBTL1 DAGLA

9.62e-0610216569734811
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

SEMA4F MYCBP2 PIGS COLGALT1 WDR59 MAP7D1 FOXRED2 PTPN13 G3BP1 COMMD9 NUP210 UGGT2 DOCK6 HECTD1

1.60e-057541651433060197
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

AUP1 ST7 PIGS GPAT3 COLGALT1 ATL1 AREL1 NUP210 UGGT2 SEC23B STX6

1.60e-054681651131056421
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

GALNT1 COPA MYCBP2 PIGS HLA-E HLA-F DAG1 LAMC3 COLGALT1 PLA2G15 TXNDC11 CUTA FOXRED2 NUP210 DPY19L4 UGGT2 TTC17 HECTD1

1.76e-0512011651835696571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4F LRWD1 MYCBP2 LAD1 HECTD4 LAMC3 CLASP2 ICE1 GRIN2D WDR59 RALGPS1 ZNF398 HMGXB3 WDR90 DOCK6 HECTD1 HOXB13

2.20e-0511051651735748872
Pubmed

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.

CLASP1 CLASP2

2.24e-052165216914514
Pubmed

Gabra5-gene haplotype block associated with behavioral properties of the full agonist benzodiazepine chlordiazepoxide.

OCA2 GABRA5

2.24e-052165222677273
Pubmed

A deletional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin Tokyo (beta 220/216).

SPTA1 SPTB

2.24e-05216521391962
Pubmed

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.

CLASP1 CLASP2

2.24e-052165216866869
Pubmed

The ferroportin-ceruloplasmin system and the mammalian iron homeostasis machine: regulatory pathways and the role of lactoferrin.

SLC40A1 LTF

2.24e-052165229453656
Pubmed

Chaperone activity and prodan binding at the self-associating domain of erythroid spectrin.

SPTA1 SPTB

2.24e-052165215492010
Pubmed

Beta spectrin kissimmee: a spectrin variant associated with autosomal dominant hereditary spherocytosis and defective binding to protein 4.1.

SPTA1 SPTB

2.24e-05216528102379
Pubmed

Beta-spectrin Promiss-ao: a translation initiation codon mutation of the beta-spectrin gene (ATG --> GTG) associated with hereditary spherocytosis and spectrin deficiency in a Brazilian family.

SPTA1 SPTB

2.24e-05216529414314
Pubmed

Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells.

CLASP1 CLASP2

2.24e-052165219701196
Pubmed

Mutation of a highly conserved residue of betaI spectrin associated with fatal and near-fatal neonatal hemolytic anemia.

SPTA1 SPTB

2.24e-05216529005995
Pubmed

Identification of the molecular defect in the erythrocyte membrane skeleton of some kindreds with hereditary spherocytosis.

SPTA1 SPTB

2.24e-05216527104494
Pubmed

A genetic defect in the binding of protein 4.1 to spectrin in a kindred with hereditary spherocytosis.

SPTA1 SPTB

2.24e-05216526215583
Pubmed

Bi-Allelic Mutations in NUP205 and NUP210 Are Associated With Abnormal Cardiac Left-Right Patterning.

NUP205 NUP210

2.24e-052165231306055
Pubmed

Spectrin Nice (beta 220/216): a shortened beta-chain variant associated with an increase of the alpha I/74 fragment in a case of elliptocytosis.

SPTA1 SPTB

2.24e-05216523580577
Pubmed

Recurrent fatal hydrops fetalis associated with a nucleotide substitution in the erythrocyte beta-spectrin gene.

SPTA1 SPTB

2.24e-05216527883966
Pubmed

Spectrin Cosenza: a novel beta chain variant associated with Sp alphaI/74 hereditary elliptocytosis.

SPTA1 SPTB

2.24e-05216529163587
Pubmed

Identification of three novel spectrin alpha I/74 mutations in hereditary elliptocytosis: further support for a triple-stranded folding unit model of the spectrin heterodimer contact site.

SPTA1 SPTB

2.24e-05216528018926
Pubmed

HLA-E and HLA-F Are Overexpressed in Glioblastoma and HLA-E Increased After Exposure to Ionizing Radiation.

HLA-E HLA-F

2.24e-052165235181585
Pubmed

HLA-F complex without peptide binds to MHC class I protein in the open conformer form.

HLA-E HLA-F

2.24e-052165220483783
Pubmed

Erythrocyte spectrin is comprised of many homologous triple helical segments.

SPTA1 SPTB

2.24e-05216526472478
Pubmed

ZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1E.

TRIP6 PTPN13

2.24e-052165210400701
Pubmed

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.

CLASP1 CLASP2

2.24e-052165212837247
Pubmed

An insertional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin nice (beta 220/216).

SPTA1 SPTB

2.24e-05216522070088
Pubmed

Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis.

SPTA1 SPTB

2.24e-05216529373273
Pubmed

Novel mutations in SPTA1 and SPTB identified by whole exome sequencing in eight Thai families with hereditary pyropoikilocytosis presenting with severe fetal and neonatal anaemia.

SPTA1 SPTB

2.24e-052165230198572
Pubmed

Spectrin mutations in hereditary elliptocytosis and hereditary spherocytosis.

SPTA1 SPTB

2.24e-05216528844207
Pubmed

Spectrin Rouen (beta 220-218), a novel shortened beta-chain variant in a kindred with hereditary elliptocytosis. Characterization of the molecular defect as exon skipping due to a splice site mutation.

SPTA1 SPTB

2.24e-05216522056132
Pubmed

Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis.

SPTA1 SPTB

2.24e-05216522346784
Pubmed

Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization.

CLASP1 CLASP2

2.24e-052165210899121
Pubmed

Spectrin cagliari. an Ala-->Gly substitution in helix 1 of beta spectrin repeat 17 that severely disrupts the structure and self-association of the erythrocyte spectrin heterodimer.

SPTA1 SPTB

2.24e-05216528226774
Pubmed

Properties of human red cell spectrin heterodimer (side-to-side) assembly and identification of an essential nucleation site.

SPTA1 SPTB

2.24e-05216521634521
Pubmed

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.

GK GK2

2.24e-052165230662012
Pubmed

Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis.

SPTA1 SPTB

2.24e-052165222164239
Pubmed

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.

SPTA1 SPTB

2.24e-052165220197550
Pubmed

Human leukocyte antigen (HLA)-E and HLA-F expression in gastric cancer.

HLA-E HLA-F

2.24e-052165225862890
Pubmed

A structural model of the erythrocyte spectrin heterodimer initiation site determined using homology modeling and chemical cross-linking.

SPTA1 SPTB

2.24e-052165217977835
Pubmed

gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer.

GALNT1 UGT1A1 SEC23B

2.90e-051316539472029
Pubmed

Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs.

CD207 HLA-E HLA-F

2.90e-0513165333542915
Pubmed

A trans-eQTL network regulates osteoclast multinucleation and bone mass.

SLC1A4 SLC40A1 EML1

3.67e-0514165332553114
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SEMA4F CLASP1 MYCBP2 GPAT3 CLASP2 ICE1 WDR59 ATL1 TBC1D31 NFRKB UGGT2 TTC17 HECTD1

5.16e-057331651334672954
Pubmed

The DNA sequence of human chromosome 7.

DOCK4 DPP6 TRIM73 ST7 ZNF212 HOXA13 ZNF398 TRIM50 ZNF282 TRIM74

5.29e-054411651012853948
Pubmed

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

TRIM73 TRIM50 TRIM74

5.61e-0516165322792322
Pubmed

The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL.

TRIP6 PTPN13

6.69e-053165210826496
Pubmed

The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides.

HLA-E HLA-F

6.69e-053165210430630
Pubmed

Characterization of a new subfamily of class I genes in the H-2 complex of the mouse.

HLA-E HLA-F

6.69e-05316523378834
Pubmed

CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development.

CLASP1 CLASP2

6.69e-053165228285824
Pubmed

Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.

SV2A SV2C

6.69e-053165223617838
Pubmed

Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells.

HLA-E HLA-F

6.69e-053165228740236
Pubmed

Comparative genomic aspects of rat, mouse and human MHC class I gene regions.

HLA-E HLA-F

6.69e-053165211173841
Pubmed

Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.

HLA-E HLA-F

6.69e-05316521327207
Pubmed

Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.

GK GK2

6.69e-053165228852571
Pubmed

The carboxyterminal EF domain of erythroid alpha-spectrin is necessary for optimal spectrin-actin binding.

SPTA1 SPTB

6.69e-053165220585040
Pubmed

Fine map of a region homologous to the rat grc complex in the TL region of the mouse.

HLA-E HLA-F

6.69e-05316528428772
Pubmed

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

UGT1A1 UGT1A3

6.69e-053165212051676
Pubmed

CTL and sequence analyses of MHC class IB antigens Qa1(c) (H2-T23(r)) and Qa1(d) (H2-T23(f)).

HLA-E HLA-F

6.69e-053165210369933
Pubmed

Antigen-presenting cells for naive transgenic gamma delta T cells. Potent activation by activated alpha beta T cells.

HLA-E HLA-F

6.69e-05316527561093
Pubmed

Critical role of Qa1b in the protection of mature dendritic cells from NK cell-mediated killing.

HLA-E HLA-F

6.69e-053165218028286
Pubmed

Organization and structure of the H-2M4-M8 class I genes in the mouse major histocompatibility complex.

HLA-E HLA-F

6.69e-05316528319975
Pubmed

Expression of nonclassical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system.

HLA-E HLA-F

6.69e-053165218322080
Pubmed

Analysis of litter size and weight in mice differing in Ped gene phenotype and the Q region of the H-2 complex.

HLA-E HLA-F

6.69e-05316521865393
Pubmed

Hyperconservation of the N-formyl peptide binding site of M3: evidence that M3 is an old eutherian molecule with conserved recognition of a pathogen-associated molecular pattern.

HLA-E HLA-F

6.69e-053165212847252
Pubmed

Linkage of the preimplantation-embryo-development (Ped) gene to the mouse major histocompatibility complex (MHC).

HLA-E HLA-F

6.69e-05316523593832
Pubmed

In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin.

FN1 MYOC

6.69e-053165211773026
Pubmed

Duplicated gene pairs and alleles of class I genes in the Qa2 region of the murine major histocompatibility complex: a comparison.

HLA-E HLA-F

6.69e-05316523004940
Pubmed

Murine MHC class Ib gene, H2-M2, encodes a conserved surface-expressed glycoprotein.

HLA-E HLA-F

6.69e-053165215045471
Pubmed

Anti-band 3 and anti-spectrin antibodies are increased in Plasmodium vivax infection and are associated with anemia.

SPTA1 SPTB

6.69e-053165229884876
Pubmed

HMT, encoded by H-2M3, is a neoclassical major histocompatibility class I antigen.

HLA-E HLA-F

6.69e-05316528464890
Pubmed

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

HLA-E HLA-F

6.69e-05316528245452
Pubmed

Uterine inflammatory myofibroblastic tumor: First report of a ROS1 fusion.

FN1 ROS1

6.69e-053165234322931
Pubmed

Expression of SV2 isoforms during rodent brain development.

SV2A SV2C

6.69e-053165223937191
Pubmed

Identification of two major histocompatibility complex class Ib genes, Q7 and Q9, as the Ped gene in the mouse.

HLA-E HLA-F

6.69e-053165210208972
Pubmed

BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1.

HLA-E HLA-F

6.69e-05316521545794
Pubmed

Extension of the H-2 TLb molecular map. Isolation and characterization of T13, T14, and T15 from the C57BL/6 mouse.

HLA-E HLA-F

6.69e-05316522831142
Pubmed

Two "Qa" specificities: Qa-m7 and Qa-m8 defined by monoclonal antibodies.

HLA-E HLA-F

6.69e-05316526190932
Pubmed

Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns.

SV2A SV2C

6.69e-053165233588752
Pubmed

Analysis of the Qa-4 allodeterminant.

HLA-E HLA-F

6.69e-05316522581893
Pubmed

Class Ib MHC-Mediated Immune Interactions Play a Critical Role in Maintaining Mucosal Homeostasis in the Mammalian Large Intestine.

HLA-E HLA-F

6.69e-053165234911745
Pubmed

Repression of the nonclassical MHC class I gene H2-M1 by cis-acting silencer DNA elements.

HLA-E HLA-F

6.69e-05316528753857
Pubmed

Combinatorial coexpression of neural and immune multigene families in mouse vomeronasal sensory neurons.

HLA-E HLA-F

6.69e-053165212620187
Pubmed

Expression in L cells of transfected class I genes from the mouse major histocompatibility complex.

HLA-E HLA-F

6.69e-05316522991930
InteractionFBXO2 interactions

FN1 ADAM23 PIGS DAG1 LAMC3 ADGRV1 PLA2G15 TXNDC11 NUP210 CTHRC1 TTC17 GALNT5 PLXNA2 CNTN1

5.74e-0641116114int:FBXO2
GeneFamilyDyneins, axonemal

DNAH10 DNAH2 DNAH17 DNAH8 DNAH9

4.44e-08171105536
GeneFamilyFibronectin type III domain containing

MPL FN1 PTPRH ROS1 SDK1 CNTN1

4.39e-041601106555
GeneFamilyGlycerol kinases

GK GK2

5.42e-0461102568
GeneFamilyEF-hand domain containing|Spectrins

SPTA1 SPTB

7.55e-04711021113
GeneFamilyWD repeat domain containing

LRWD1 COPA WDR59 TBC1D31 EML5 WDR90 EML1

1.11e-032621107362
CoexpressionGSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_UP

RASGRF1 ADAM23 HLA-E TEX14 COLGALT1 WDR59 DNAH17 NUP210 PLCB3

4.28e-061951659M9873
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 SPTA1 ADGRV1 PKD1L2 PIEZO2 ROS1 DNAH9 SDK1 CNTN1

3.20e-0818416692cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 SPTA1 ADGRV1 PKD1L2 PIEZO2 ROS1 DNAH9 SDK1 CNTN1

3.20e-081841669ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 SPTA1 ADGRV1 PKD1L2 PIEZO2 ROS1 DNAH9 SDK1 CNTN1

3.20e-0818416692b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L DPP6 ST7 SYNE1 ADGRV1 GPR160 PTPN13 ROS1 PDZD2

5.05e-08194166997534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 TRIM73 DNAH2 ADGRV1 CFAP54 DNAH9 SDK1 PLXNA2

6.70e-071931668ea345d34440b25f65358a53dc72831998d1c3620
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PIEZO2 PDGFD EML1 DOCK6

7.53e-071961668d323f7dc41380446e5967c69832bea88351a9331
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 DPP6 CLASP1 ST7 ADGRV1 PTPN13 SDK1 PDZD2

8.12e-0719816681996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 FN1 HLA-E F8 PDGFD EML1 DOCK6 PLXNA2

8.12e-0719816688689090bce9ab6e8f122426a404037e572c6713b
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST7 LAMC3 KCNT2 CTNNA3 SNTG2 CNTN1 PDZD2

5.99e-061841667327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

USP53 DOCK4 FN1 SLC40A1 MOXD1 PIEZO2 CNTN1

7.38e-06190166771e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L DPP6 RASGRF1 ADGRV1 PTPN13 ROS1 PDZD2

7.64e-061911667a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

DOCK4 SYNE1 HLA-E F8 EML1 DOCK6 PLXNA2

7.64e-061911667c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

DOCK4 SYNE1 HLA-E F8 EML1 DOCK6 PLXNA2

7.90e-0619216678a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 FN1 OCA2 SLC40A1 MOXD1 PIEZO2 CNTN1

8.18e-0619316679f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

DOCK4 FN1 HLA-E ITGA10 F8 KCNT2 PLXNA2

8.18e-06193166701c2df9206f1527c578e808978e58196c35e72f5
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 SYNE1 HLA-E F8 PIEZO2 PDGFD EML1

8.46e-061941667660535b492445063d965095a50e1e299ce04c50a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 FN1 F8 PIEZO2 PDGFD EML1 DOCK6

8.46e-061941667e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell(7)_Epithelial-A_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SECISBP2L RASGRF1 LAD1 GPR160 PTPN13 ROS1 CNTN1

8.74e-061951667c9a6c65ee18d83bf34a4713d306a6e30db1325c2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PIEZO2 PDGFD EML1

8.74e-06195166723ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

USP53 DPP6 FN1 SLC40A1 MOXD1 PIEZO2 SDK1

8.74e-061951667603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 DPP6 CLASP1 ST7 ADGRV1 SDK1 PDZD2

9.04e-061961667ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SECISBP2L RASGRF1 SYNE1 ADGRV1 PTPN13 ROS1 PDZD2

9.04e-0619616677e5addaa844e66f8160e05858c341866a80aed23
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 SYNE1 DNAH2 LRRC9 CFAP54 WDR90 DNAH9

9.35e-06197166774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

DOCK4 SYNE1 HLA-E F8 SNTG2 EML1 PLXNA2

9.35e-061971667f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E PIEZO2 PDGFD EML1 DOCK6

9.66e-06198166731ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PDGFD EML1 DOCK6

9.66e-0619816671378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PDGFD EML1 DOCK6

9.66e-061981667451003a21162eeae90739fdb502bb50b362d80c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PIEZO2 PDGFD EML1

9.66e-06198166792416e65a0dc1a4bf931833407620ea05d362f56
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PDGFD EML1 DOCK6

9.66e-061981667440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FN1 MYCBP2 SYNE1 SLC40A1 MOXD1 PDGFD LRRC15

9.98e-061991667a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellCOVID-19-kidney-Glomerular_EC|kidney / Disease (COVID-19 only), tissue and cell type

DOCK4 SYNE1 HLA-E F8 PIEZO2 PDGFD EML1

9.98e-061991667fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 FN1 HLA-E F8 PDGFD EML1 DOCK6

1.03e-052001667b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 FN1 HLA-E F8 PDGFD EML1 DOCK6

1.03e-052001667ced14d83222dbebca85c40540e76824e683354f3
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 PMEL L3MBTL1 ROS1 DDX43 DNAH9

1.50e-0514116664aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 PMEL L3MBTL1 ROS1 DDX43 DNAH9

1.50e-051411666e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 GPAT3 IL18RAP SLC40A1 SV2A LTF

3.06e-051601666bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 GPAT3 IL18RAP SLC40A1 SV2A LTF

3.06e-05160166676f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SPTA1 CFAP54 PIEZO2 SNTG2 LRRC15

3.16e-051611666fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SPTA1 CFAP54 PIEZO2 SNTG2 LRRC15

3.16e-051611666c53c461fc721a7960cef86662f49e2a495520701
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 FN1 HOXA13 PTCHD1 PIEZO2 CNTN1

3.16e-0516116661b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

IL10RA CLASP2 NUP205 TBC1D31 ZNF398 EPB42

3.75e-051661666a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 HECTD4 TUBGCP5 PTPN13 EML5 ROS1

3.75e-05166166689e2b8453180983533faccb4275867861876d7ee
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 CFAP54 CFAP206 DNAH9 SDK1 UPK3BL1

3.75e-0516616664b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA FN1 TRIP6 PKD1L2 PTPN13 RALGPS1

4.01e-0516816662e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC40A1 PTPRH LTF DOCK6 HOXB13 XPR1

4.01e-05168166603896466698a79f7f1ad862cb7e05585260e2a5a
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VPS8 FOXRED2 PTPN13 SV2C WDR90 CNTN1

4.01e-051681666a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 F8 PIEZO2 PDGFD EML1

4.15e-051691666987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellhealthy_donor-Myeloid-Monocytic-Developing_Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

DNAH10 SLC1A4 GPR160 COMMD9 UGGT2 LTF

4.29e-051701666cfd7f29805b7c51666b0eaf269c36c96b8765a1a
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

SYNE1 HLA-E ITGA10 EML1 DOCK6 PLXNA2

4.43e-051711666bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SYNE1 HOXA13 PTCHD1 PIEZO2 CNTN1

4.58e-05172166608a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FN1 ADAM23 SPTB PMEL PIEZO2 PDGFD

4.58e-051721666c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 SYNE1 HOXA13 PTCHD1 PIEZO2 CNTN1

4.58e-051721666553701349444eb366df3c11f54bb093434f153c6
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM23 HECTD4 IL18RAP SLC40A1 GPR160 FOXRED2

4.58e-051721666eba1568d4307e91c94fc616549057cbed8df5840
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 GALNT1 FN1 SYNE1 F8 EML1

4.58e-051721666c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E F8 PDGFD EML1

4.73e-051731666f193c63cc536d891c9d23043765e320252bb6e65
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SYNE1 HLA-E PIEZO2 PDGFD EML1

4.73e-051731666afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCelldroplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAD1 ITGA10 SH2D4A CFAP206 LTF DNAH9

5.37e-0517716667ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 NTN3 LRRC9 TBC1D31 L3MBTL1 EML5

5.37e-0517716668abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAD1 ITGA10 SH2D4A CFAP206 LTF DNAH9

5.37e-051771666092a345cb802f183322aa5542341ba2d96d4f06a
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK4 DPP6 HLA-E TAC4 PDGFD PDZD2

5.54e-051781666c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 ITGA10 F8 ATL1 PDGFD DNAH8

5.71e-051791666025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ADAM23 MOXD1 SH2D4A DPY19L4 SV2C

5.89e-051801666da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

HLA-E ITGA10 LTF EML1 DOCK6 CDH8

5.89e-051801666162cec1734e560c068cd61717e40e18dcf92308c
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

SECISBP2L RASGRF1 SYNE1 ADGRV1 PTPN13 ROS1

5.89e-051801666198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

HLA-E ITGA10 LTF EML1 DOCK6 CDH8

5.89e-05180166633c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ADAM23 MOXD1 SH2D4A DPY19L4 SV2C

5.89e-0518016665b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ADAM23 MOXD1 SH2D4A DPY19L4 SV2C

5.89e-05180166650758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HLA-F LAMC3 GRIN2D KCNT2 SDK1 LRRC15

6.26e-0518216663d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4F ADAM23 MYOC ITGA10 MOXD1 DAGLA

6.26e-051821666a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC3 KCNT2 CTNNA3 SNTG2 CNTN1 PDZD2

6.46e-0518316668a799807fbf24456a9811e0c64068187940a2f71
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GALNT1 DNAH10 SLC1A4 COMMD9 UGGT2 LTF

6.65e-051841666a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GALNT1 DNAH10 SLC1A4 COMMD9 UGGT2 LTF

6.65e-051841666081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

GALNT1 DNAH10 SLC1A4 COMMD9 UGGT2 LTF

6.65e-05184166645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 LAD1 ADGRV1 GPR160 PTPN13 ROS1

6.65e-0518416660ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GALNT1 DNAH10 SLC1A4 COMMD9 UGGT2 LTF

6.65e-05184166684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GALNT1 DNAH10 SLC1A4 COMMD9 UGGT2 LTF

6.65e-051841666d31d4116d1d196633784863781fa45673607a421
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ST7 LAMC3 KCNT2 CTNNA3 SNTG2 CNTN1

6.65e-051841666102b6f621a5b551e622f97b12d787c080b052a72
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 LAD1 ADGRV1 GPR160 PTPN13 ROS1

6.65e-0518416662a8338e94937686a148b5433515700ca0f674058
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

DNAH10 SYNE1 LAD1 HLA-E IL18RAP GZMA

6.65e-051841666791f1bcb954aadc63d4117c400537d036f68734d
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPTA1 SPTB HECTD4 SLC40A1 GALNT5 EPB42

6.86e-051851666c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCellASK440-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SYNE1 HLA-E HLA-F IL18RAP GZMA EPB42

7.06e-051861666ce8e63057a99afa0a9cbf27ae7f9a70c0e972b6d
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 PMEL KCNT2 SNTG2

7.12e-051151665ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 PMEL KCNT2 SNTG2

7.12e-0511516657a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA10 LAMC3 PMEL KCNT2 SNTG2

7.12e-051151665c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

HLA-E ITGA10 F8 SNTG2 DOCK6 PLXNA2

7.28e-0518716667876dcb4800c2e54874df3d933efb79307a64a97
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

USP53 DOCK4 DPP6 FN1 PIEZO2 SDK1

7.28e-05187166692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellwk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

F8 HSD3B7 CLRN3 CTHRC1 SV2C SNTG2

7.28e-05187166655aad84b992412e487a32f4970620189a7380ba6
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

CLASP2 NUP205 TBC1D31 POLR3E ZNF398 EPB42

7.49e-0518816668f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

HLA-E ITGA10 EML1 DOCK6 CDH8 PLXNA2

7.49e-05188166602a62888e9db29d20133eeca1686d302545a39c9
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA10 LAMC3 PTCHD1 PTPN13 PDGFD SDK1

7.49e-051881666997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYCBP2 GRIN2D CHRM5 SV2A SV2C CDH8

7.49e-051881666b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OCA2 GRIN2D FOXRED2 KCNT2 PDGFD SV2C

7.72e-051891666f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RASGRF1 SLC40A1 PTCHD1 PTPN13 ROS1 GALNT5

7.72e-0518916662d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP53 DOCK4 HLA-E PLA2G15 SLC40A1 TRIM50

7.94e-0519016660a944da2aaaef9289b2a4ffe360b0338724fd59b
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT1 COPA CLASP2 COLGALT1 PICALM LTF

7.94e-0519016661d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

DPP6 SPTA1 IL18RAP GZMA NUP210 EPB42

7.94e-051901666e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

LRWD1 NUP205 TBC1D31 CFAP206 WDR90 DNAH8

8.18e-05191166637cf121e6e80760c8519075b7845b9029958a988
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FN1 OCA2 SLC40A1 MOXD1 PIEZO2 CNTN1

8.18e-051911666fa380a8752de158974b2ae5e741573439719cc0d
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

DPP6 RASGRF1 ADGRV1 PTPN13 ROS1 PDZD2

8.41e-05192166658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLASP2 NUP205 TBC1D31 POLR3E ZNF398 EPB42

8.41e-051921666445985fe1bcd33e4f0a1704b27988fbfc9334538
Diseasehereditary spherocytosis (is_implicated_in)

SPTA1 SPTB EPB42

1.49e-0651583DOID:12971 (is_implicated_in)
DiseaseHereditary spherocytosis

SPTA1 SPTB EPB42

1.49e-0651583cv:C0037889
DiseaseAnemia, hereditary spherocytic hemolytic

SPTA1 SPTB EPB42

1.49e-0651583C0221409
DiseaseElliptocytosis, Hereditary

SPTA1 SPTB EPB42

2.98e-0661583C0013902
DiseaseHereditary spherocytosis

SPTA1 SPTB EPB42

8.27e-0681583C0037889
Diseaseglycerol kinase deficiency (implicated_via_orthology)

GK GK2

8.52e-0531582DOID:0060363 (implicated_via_orthology)
DiseaseAutism Spectrum Disorders

DPP6 LAMC3 PTCHD1 SNTG2 GABRA5

9.60e-05851585C1510586
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

DNAH10 UGT1A1 UGT1A3

9.69e-05171583EFO_0004611, EFO_0007800
Diseaseforced expiratory volume, response to bronchodilator

DPP6 GALNT1 SYNE1 CD207 KERA ADGRV1 NUP205 PIEZO2 KCNT2 SNTG2

1.51e-0444515810EFO_0004314, GO_0097366
Diseasereticulocyte count

DNAH10 CLASP1 SPTA1 SPTB SNX17 HECTD4 TAC4 TSEN2 PICALM PTPRH DNAH17 NFRKB SV2C PLCB3 EPB42 PDZD2

1.63e-04104515816EFO_0007986
DiseaseElliptocytosis found

SPTB EPB42

1.70e-0441582C0427480
DiseaseHereditary elliptocytosis

SPTA1 SPTB

1.70e-0441582cv:C0013902
Diseasehereditary spherocytosis type 1 (implicated_via_orthology)

SPTA1 EPB42

1.70e-0441582DOID:0110916 (implicated_via_orthology)
Diseaseobsolete_red blood cell distribution width

CLASP1 SPTA1 SPTB HECTD4 TAC4 PICALM F8 SLC40A1 TXNDC11 INTS10 PTPRH G3BP1 NUP210 NFRKB SV2C DOCK6 DAGLA SEC23B

3.35e-04134715818EFO_0005192
Diseaseurate measurement, bone density

CRACR2A SYNE1 CLASP2 TAC4 ATL1 SH2D4A POLR3E UGGT2 DNAH8 DNAH9 PDZD2

5.30e-0461915811EFO_0003923, EFO_0004531
Diseaseserum metabolite measurement

RASGRF1 CD207 LAMC3 PKD1L2 PLA2G15 SLC1A4 FMO6P ATL1 UGT1A1 UGT1A3 KCNT2 PTPRH DNAH17 DOCK6

5.85e-0494515814EFO_0005653
Diseasegraft-versus-host disease (implicated_via_orthology)

HLA-E HLA-F

5.88e-0471582DOID:0081267 (implicated_via_orthology)
DiseaseX-11442 measurement

UGT1A1 UGT1A3

1.00e-0391582EFO_0021236
DiseaseX-11441 measurement

UGT1A1 UGT1A3

1.00e-0391582EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A1 UGT1A3

1.00e-0391582EFO_0004739
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A1 UGT1A3

1.00e-0391582EFO_0004570, GO_0009410
DiseaseHamartoma Syndrome, Multiple

SEC23B SDHD

1.00e-0391582C0018553
Diseasebilirubin measurement, response to tenofovir

UGT1A1 UGT1A3

1.25e-03101582EFO_0004570, EFO_0009279
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A1 UGT1A3

1.25e-03101582EFO_0802185
Diseasemembranoproliferative glomerulonephritis (biomarker_via_orthology)

FN1 MYOC

1.25e-03101582DOID:2920 (biomarker_via_orthology)
Diseasehistidine betaine (hercynine) measurement

UGT1A1 UGT1A3

1.52e-03111582EFO_0800972
DiseaseX-21796 measurement

UGT1A1 UGT1A3

1.52e-03111582EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A1 UGT1A3

1.52e-03111582EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A1 UGT1A3

1.52e-03111582EFO_0010219
Diseasebiliverdin measurement

UGT1A1 UGT1A3

1.82e-03121582EFO_0021033
DiseaseCOVID-19, mortality

GRIN2D CTNNA3 SNTG2 PDZD2 GABRA5

2.27e-031701585EFO_0004352, MONDO_0100096
Diseasetotal brain volume change measurement

DPP6 CDH8

2.49e-03141582EFO_0021504
Diseaselevel of Phosphatidylethanolamine (18:2_0:0) in blood serum

SNX17 DAGLA

2.49e-03141582OBA_2045143
Diseasewaist-hip ratio

NUDT18 FN1 DNAH10 MYCBP2 ADAM23 HECTD4 DAG1 COL5A1-AS1 TSEN2 NUP205 SLC35F5 KCNT2 DNAH17 PLCB3 DOCK6

2.51e-03122615815EFO_0004343
Diseasegamma-glutamylphenylalanine measurement

DPP6 CTNNA3

2.86e-03151582EFO_0021142
DiseaseAutistic Disorder

DOCK4 KMT2E SLC40A1 PTCHD1 SNTG2 GABRA5

2.90e-032611586C0004352
DiseaseIntellectual Disability

SYNE1 GRIN2D KMT2E TSEN2 SLC1A4 ATL1 PTCHD1 SMARCC2

2.91e-034471588C3714756
DiseaseSchizophrenia

IL10RA DOCK4 HLA-E GRIN2D CHRM5 UGT1A3 EML5 SV2A ADGRF4 STH PLXNA2 GABRA5

2.94e-0388315812C0036341
Diseasepathological myopia

SEMA4F ROS1 DNAH9 CDH8

3.04e-031111584EFO_0004207
Diseasevision disorder

SDK1 CNTN1

3.25e-03161582MONDO_0021084
Diseasedisease free survival

ICE1 CDH8

4.12e-03181582EFO_0000409
Diseasereticulocyte measurement

DNAH10 CLASP1 SPTA1 SPTB HECTD4 TAC4 TSEN2 PICALM PTPRH DNAH17 SV2C PLCB3 PDZD2

4.48e-03105315813EFO_0010700
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

4.59e-03191582DOID:10003 (implicated_via_orthology)
Diseaseiron biomarker measurement, ferritin measurement

TEX14 SLC40A1

4.59e-03191582EFO_0004459, EFO_0004461
DiseaseUlcerative Colitis

IL10RA IL18RAP LTF

4.73e-03631583C0009324
Diseaseblood aluminium measurement

DPP6 GK2

5.08e-03201582EFO_0007575

Protein segments in the cluster

PeptideGeneStartEntry
NISDLDTIWLVVALS

UPK3BL1

76

B0FP48
DTIWLVVALSNATQS

UPK3BL1

81

B0FP48
REVSVVDILSHASVW

UGT1A3

241

P35503
SAVVEERDAQSWTIS

EPB42

91

P16452
LREVQTLSWPRTVTE

CFAP54

381

Q96N23
LNTRVVLVAVETWTE

ADAM23

341

O75077
ASTGWNSVSRIIIEE

CTHRC1

226

Q96CG8
TATTEVRESWLLTKL

ADGRG4

901

Q8IZF6
EDSRTRTILWVQAAT

HSD3B7

351

Q9H2F3
AISSREQVDRLLSTW

CALHM3

291

Q86XJ0
LQWVRQVTESVSDSI

CUTA

161

O60888
SWSDTLREVNITIID

GZMA

161

P12544
IIEATVWSRVVVTEI

ADGRF4

421

Q8IZF3
IDLAVSVQWETVSET

ADGRV1

3231

Q8WXG9
VDENTWTNLLSRVTL

CEP44

271

Q9C0F1
QSFLSVRRWLSSVEE

CRACR2A

631

Q9BSW2
AASLHWTSERVVSVL

SDHD

61

O14521
LSTLWTSLQDETIVV

CFAP206

326

Q8IYR0
VLVVWVSALASSLID

OCA2

726

Q04671
IREQQRSAVSTSWLL

PLA2G15

256

Q8NCC3
VSFWVVREILTAQTL

RALGPS1

101

Q5JS13
LRSWTAADTVAQITQ

HLA-F

151

P30511
VWREISIITSALRND

INTS10

76

Q9NVR2
LQLTSTIITWSENAR

NUP205

601

Q92621
QELNWTSSSIRTVDL

LRRC9

1096

Q6ZRR7
QSTVAVVVLARLQWS

LRWD1

536

Q9UFC0
VVVLARLQWSSTELA

LRWD1

541

Q9UFC0
SEIQELLTTALVSWL

ANKAR

41

Q7Z5J8
SIQWESTRPVLASIE

NUP210

806

Q8TEM1
LRSWTAVDTAAQISE

HLA-E

151

P13747
SDTVSSWTVRAVVQV

IL18RAP

226

O95256
LVDLRISWTTTNRDI

KIAA0100

1451

Q14667
VTSRLNLWISRTQES

LAD1

471

O00515
DVVSLSTWQEVLSDS

NFRKB

51

Q6P4R8
AVVWLDLRTQSTVES

GK3P

111

Q14409
RLVATFTSAQTVWVL

NUDT18

191

Q6ZVK8
TLQNITRGSIVVEWT

DAG1

646

Q14118
WLLTASRLQTVTAQV

HMGXB3

771

Q12766
VEDISETSTIIRGRW

PDGFD

116

Q9GZP0
LEVDSRSVVLLSVVW

PLXNA2

11

O75051
STSTVRLLEWTEAAA

L3MBTL1

76

Q9Y468
SLSTTQVESPWRLIR

PDZD2

566

O15018
LSTSSDIIEEWLVVQ

DNAH8

1481

Q96JB1
TQETTWRIDTVGTDV

MYOC

281

Q99972
QWTASTSVEQVRERS

KMT2E

1251

Q8IZD2
TVILSQVSFWLNRES

GABRA5

271

P31644
TETQVIRETLWLLSG

TUBGCP5

266

Q96RT8
QTVSLLFSLWVETVR

TUBGCP5

456

Q96RT8
WTVTNTRFSVDEVTL

IL10RA

111

Q13651
LEKRIIVDDTSTQWS

F8

1346

P00451
LATQVIISTRSASWV

FMO6P

206

O60774
RVVSETKESVTLTWN

LRIT3

491

Q3SXY7
LTTSESQISISVEEW

KCNT2

966

Q6UVM3
VSTESLWQHRVESRL

FOXRED2

626

Q8IWF2
AQIWTTTAEKVLSRA

HECTD4

1681

Q9Y4D8
TSEWHVTAQRQVTVR

PKD1L2

326

Q7Z442
WEEVTTLVQAIRITS

GPR160

201

Q9UJ42
LQDWVTATDVRVVLT

NTN3

211

O00634
WDEETSSRNLVTLRV

PLCB3

31

Q01970
IILEHVSTWRTEAQA

COMMD9

101

Q9P000
SVLLASVEEATWNLL

CTNNA3

56

Q9UI47
NEAWSTLLRTVHSVI

GALNT1

126

Q10472
VVTLRNIATQLESSW

HECTD1

856

Q9ULT8
WTRINEITSEPDRIT

ICE1

566

Q9Y2F5
SERETTGIQIWSEIF

ATL1

116

Q8WXF7
RETWRESGVSLIATV

DOCK4

1141

Q8N1I0
ELALQWVVSSSAVRE

DOCK6

911

Q96HP0
AVVWLDLRTQTTVED

GK2

111

Q14410
TADSVISIWFEVQRT

DNAH17

1481

Q9UFH2
FSSEELVSWNLLTRT

GPAT3

116

Q53EU6
ARVTDATETTITISW

FN1

1911

P02751
VSASLDQTVRVWDIS

COPA

151

P53621
DEVWSTLLRSVHSVI

GALNT5

506

Q7Z7M9
TVQEDLRTFSWASVT

G3BP1

241

Q13283
RIEDIRATSVALTWS

CNTN1

611

Q12860
TVAWFVINRVDTTRI

DPY19L4

196

Q7Z388
AVVWLDLRTQSTVES

GK

111

P32189
FWTVVSSLTQEELAR

AREL1

736

O15033
WISESQVSQTTEVLT

LYG1

121

Q8N1E2
SLQLSAWESSIVDRL

MAP7D1

286

Q3KQU3
SVLQLTEASRWSESL

ITGA10

1096

O75578
TEASRWSESLLEVVQ

ITGA10

1101

O75578
EVEVTTLASTRLWTH

DAGLA

571

Q9Y4D2
LLLWISDTRAETTLT

IGKV5-2

11

P06315
QVVSVETTRDIEWAT

EML1

706

O00423
VTGSDDRSVRIWSLV

EML5

341

Q05BV3
STVWNTLSSLRAVAE

DNAH9

1361

Q9NYC9
RELSVWHNITIIATE

CDH8

456

P55286
LWALTSSEVLSAEQI

DNAAF5

681

Q86Y56
RLWNVETNTSTVLIE

DPP6

166

P42658
NTSTVLREWLVAVKS

COLGALT1

96

Q8NBJ5
AATSLSERQITIWFQ

HOXB13

251

Q92826
NILVHTVDTTRTTWI

DNAH10

2426

Q8IVF4
IDELVRKTFQEWTSS

DNAH2

591

Q9P225
WRSDLQSSAVAQVVS

SDK1

1216

Q7Z5N4
TQSRWVVRKEVATVT

POLR3E

361

Q9NVU0
AVASESSIILWSVQD

KCTD3

251

Q9Y597
VSITTLTRNDWRVAS

DDX43

586

Q9NXZ2
TATVEVSIIESTWVS

CDH16

226

O75309
WSIVSSPEREITLVN

PTPN13

1081

Q12923
LLWARSVENLATATT

PIGS

426

Q96S52
QEVILSRWVSSRERS

TSEN2

446

Q8NCE0
NISDLDTIWLVVALS

UPK3BL2

76

E5RIL1
DTIWLVVALSNATQS

UPK3BL2

81

E5RIL1
EQVSRVETTLTSWLD

TCAIM

181

Q8N3R3
LTISAWNSLDVVTVE

SV2C

646

Q496J9
WSESSRIIVLDQSDL

TEX14

1481

Q8IWB6
TQISLNRRAVEWDTT

TBC1D31

1021

Q96DN5
WLLVGSRTEVTQVNT

SEMA4F

496

O95754
LLLVDVIWVASSELT

SLC35F5

76

Q8WV83
AVAVVRRSDTSLTWN

LTF

456

P02788
RLRVSLSIWDDVLST

SYNE1

2191

Q8NF91
TDLTTIQVTDDRSVW

LRRC15

516

Q8TF66
SLINVWITLTVVSVE

PTCHD1

721

Q96NR3
RAVELVNTWTERSTQ

FGD1

476

P98174
VLFITDTVWSRSVRQ

KERA

11

O60938
STATREEIDWTTNEL

STX6

36

O43752
ASTATAITIQRDWIV

SLC40A1

146

Q9NP59
RIESWVSETQRTMET

SECISBP2L

1016

Q93073
WSRVTKNAIAETIIA

MYCBP2

4191

O75592
NFTWINSRTVVLLDS

VPS8

406

Q8N3P4
TDWLRAVSANIRELT

SNTG2

266

Q9NY99
SSDWVTTDIQVKVRD

SUPT5H

976

O00267
SLDTVVSVLRSWDLS

IQANK1

266

A8MXQ7
RSRVEVPLIASSTIW

ST7

216

Q9NRC1
AQVTTTEWVETTARE

PMEL

416

P40967
TVILVASSRQEKAAW

RASGRF1

561

Q13972
SATREWTEQETLLLL

SMARCC2

596

Q8TAQ2
SATTNLSERQVTIWF

HOXA13

356

P31271
IRVTTIARNWADVQS

SEC23B

496

Q15437
VSIASWNALDVLTVE

SV2A

661

Q7L0J3
RLWEVITIAAVTAVV

CHRM5

26

P08912
SSSVRVEWIAAVTIA

CISD1

6

Q9NZ45
QIQILTRSWEEVSTL

CD207

136

Q9UJ71
QAWITSTIAVRDSAS

CLRN3

31

Q8NCR9
IKEASISWAETSRQI

COL5A1-AS1

41

Q5SY13
NSSETRLAVSRIITW

CLASP1

1016

Q7Z460
SETRLAVSRVITWTT

CLASP2

816

O75122
LVSVTVSDASWVSEL

AUP1

196

Q9Y679
VSTEDALRQVISWSH

USP53

356

Q70EK8
DSLFERTTNSSWVVV

PICALM

61

Q13492
DVILRFAWTIQISIT

XPR1

566

Q9UBH6
AQTVSDIERGWILVT

SNX17

226

Q15036
RTRIVNESDVFSWVI

TRIM74

161

Q86UV6
SAWRIQELSATVTTD

TRIP6

461

Q15654
ATVSQDRTVRIWDLA

WDR90

716

Q96KV7
TTTVASREQLSIQWS

VSIG1

46

Q86XK7
INDKSITDSTVRVIW

MOXD1

131

Q6UVY6
VTERTVSLWSLINSN

MTM1

491

Q13496
NIRDSWEEVKLSTLT

TIGD1

386

Q96MW7
VDWIVDRTTTVVNVE

SLC1A4

451

P43007
ISLWTVVAAVQAIER

ZNF398

41

Q8TD17
WLNSISREHIDISTV

PIEZO2

1666

Q9H5I5
EVTVQDLLSSASVWL

UGT1A1

241

P22309
VRTLSSSAQEDIIRW

SH2D4A

311

Q9H788
TTVRSDTSLIISWRE

ROS1

1566

P08922
AWEVASLLTLSSSEV

STH

51

Q8IWL8
ASDLLTWIEQTITVL

SPTB

311

P11277
DNVTTRLSEVASLWE

SPTA1

656

P02549
TRVETATETAWISLV

MPL

481

P40238
VTDVTTSSLRLNWEA

TNXA

151

Q16473
VELTAIVSTWLAVSS

TTC17

911

Q96AE7
DLVQVWSLATVATDL

WDR59

691

Q6PJI9
LITEVTTDTFWEVVL

TXNDC11

691

Q6PKC3
TTEISLWTVVAAIQA

ZNF212

36

Q9UDV6
RTRIVNESDVFSWVI

TRIM73

161

Q86UV7
TQDDESIISAVTLWI

UGGT2

731

Q9NYU1
RTRIVNESDVFSWVI

TRIM50

161

Q86XT4
VEAQTTSSISLSWEV

PTPRH

216

Q9HD43
QTLSTEAETWVIVAL

TAC4

26

Q86UU9
ISLWTVVAAIQAVER

ZNF282

96

Q9UDV7
QEWVTSTELLISLDR

LAMC3

226

Q9Y6N6
SLVVISLTRDRTWEV

GRIN2D

386

O15399