Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.77e-0728364GO:0001972
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.48e-0735364GO:0015020
GeneOntologyMolecularFunctionretinoid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.64e-0648364GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.78e-0649364GO:0019840
GeneOntologyMolecularFunctiontranscription factor binding

LATS1 NFAT5 CLOCK CREBBP NCAPG2 CNOT2 MED12 DDX5 NR5A2

5.54e-06753369GO:0008134
GeneOntologyMolecularFunctionprotein kinase C binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.92e-0666364GO:0005080
GeneOntologyMolecularFunctionfatty acid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.07e-0669364GO:0005504
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.02e-05107364GO:0033293
GeneOntologyMolecularFunctionchromatin binding

CHD7 NFAT5 CLOCK CREBBP STAG2 MED12 DDX5 NR5A2

4.08e-05739368GO:0003682
GeneOntologyMolecularFunctionferroxidase activity

CP HEPH

4.72e-056362GO:0004322
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, oxygen as acceptor

CP HEPH

4.72e-056362GO:0016724
GeneOntologyMolecularFunctionsteroid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.39e-05133364GO:0005496
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.61e-04153364GO:0008194
GeneOntologyMolecularFunctioncopper ion binding

TYR CP HEPH

3.73e-0478363GO:0005507
GeneOntologyMolecularFunctiontranscription coregulator activity

SS18 CREBBP CNOT2 MED12 SS18L1 DDX5

4.59e-04562366GO:0003712
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions

CP HEPH

4.75e-0418362GO:0016722
GeneOntologyMolecularFunctionSMAD binding

BMPR1A CREBBP DDX5

4.97e-0486363GO:0046332
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.48e-04211364GO:0016758
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

8.73e-04239364GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.09e-03254364GO:0043177
GeneOntologyMolecularFunctionlipid binding

UGT1A9 ZCCHC2 UGT1A10 UGT1A8 UGT1A7 TLN1 NR5A2

1.68e-03988367GO:0008289
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.74e-03288364GO:0016757
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP NCAPG2

2.02e-0337362GO:0043425
GeneOntologyMolecularFunctiontranscription coregulator binding

CREBBP CNOT2 NR5A2

2.03e-03140363GO:0001221
GeneOntologyMolecularFunctiontranscription coactivator activity

SS18 CREBBP MED12 SS18L1

2.09e-03303364GO:0003713
GeneOntologyMolecularFunctionprotein homodimerization activity

TYR UGT1A9 BMPR1A UGT1A10 UGT1A8 UGT1A7

3.10e-03815366GO:0042803
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

LATS1 CREBBP NCAPG2 MED12 DDX5

3.69e-03582365GO:0140297
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CLOCK CREBBP

3.81e-0351362GO:0004402
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

SS18 CREBBP CNOT2 MED12 GAB1 SS18L1 DDX5

4.15e-031160367GO:0030674
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CLOCK CREBBP

4.42e-0355362GO:0061733
GeneOntologyMolecularFunctionnuclear receptor binding

LATS1 MED12 DDX5

4.60e-03187363GO:0016922
GeneOntologyMolecularFunctionprotein dimerization activity

TYR UGT1A9 BMPR1A CLOCK UGT1A10 UGT1A8 UGT1A7

5.11e-031205367GO:0046983
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CLOCK CREBBP

5.24e-0360362GO:0034212
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

SS18 MED12

5.41e-0361362GO:0030374
GeneOntologyMolecularFunctionprotein heterodimerization activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.53e-03398364GO:0046982
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

LATS1 CREBBP MED12 DDX5

6.51e-03417364GO:0061629
GeneOntologyMolecularFunctionenzyme inhibitor activity

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.54e-03435364GO:0004857
GeneOntologyMolecularFunctionN-acetyltransferase activity

CLOCK CREBBP

8.71e-0378362GO:0008080
GeneOntologyMolecularFunctionmolecular adaptor activity

SS18 CREBBP CNOT2 MED12 GAB1 SS18L1 DDX5

9.61e-031356367GO:0060090
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

CHD7 DDX5

9.81e-0383362GO:1990841
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.90e-115364GO:0006711
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.17e-106364GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.17e-106364GO:0046226
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.17e-106364GO:0051552
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.63e-0910364GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.63e-0910364GO:0009804
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.52e-0913364GO:0009812
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.58e-0821364GO:0052695
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.58e-0821364GO:0042447
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A9 UGT1A8 UGT1A7

4.87e-085363GO:0052696
GeneOntologyBiologicalProcesssecondary metabolic process

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.08e-0767365GO:0019748
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.14e-0726364GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.14e-0726364GO:0006063
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.49e-0734364GO:0006706
GeneOntologyBiologicalProcesspigment metabolic process

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.95e-0794365GO:0042440
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A9 UGT1A8 UGT1A7

1.06e-0612363GO:0052697
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.99e-0652364GO:0008210
GeneOntologyBiologicalProcessstem cell population maintenance

BMPR1A SS18 CREBBP STAG2 CNOT2 MED12

3.15e-06237366GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

BMPR1A SS18 CREBBP STAG2 CNOT2 MED12

3.56e-06242366GO:0098727
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

LATS1 CLOCK CNOT2 DDX5

1.57e-0587364GO:0033143
GeneOntologyBiologicalProcessretinoid metabolic process

LRP1 UGT1A9 UGT1A8 UGT1A7

1.72e-0589364GO:0001523
GeneOntologyBiologicalProcessditerpenoid metabolic process

LRP1 UGT1A9 UGT1A8 UGT1A7

2.13e-0594364GO:0016101
GeneOntologyBiologicalProcessterpenoid metabolic process

LRP1 UGT1A9 UGT1A8 UGT1A7

3.29e-05105364GO:0006721
GeneOntologyBiologicalProcessgland development

TYR UGT1A9 BMPR1A LATS1 UGT1A10 UGT1A8 UGT1A7

4.31e-05558367GO:0048732
GeneOntologyBiologicalProcesssteroid metabolic process

LRP1 UGT1A9 UGT1A10 UGT1A8 UGT1A7 NR5A2

4.33e-05376366GO:0008202
GeneOntologyBiologicalProcessretinoic acid metabolic process

UGT1A9 UGT1A8 UGT1A7

4.61e-0540363GO:0042573
GeneOntologyBiologicalProcessaorta morphogenesis

LRP1 BMPR1A CHD7

4.97e-0541363GO:0035909
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

LATS1 CLOCK CNOT2 DDX5 NR5A2

6.21e-05244365GO:0009755
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

LATS1 CLOCK CNOT2 DDX5

9.04e-05136364GO:0030518
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.04e-04141364GO:0006805
GeneOntologyBiologicalProcessventricular compact myocardium morphogenesis

BMPR1A CHD7

1.06e-049362GO:0003223
GeneOntologyBiologicalProcessisoprenoid metabolic process

LRP1 UGT1A9 UGT1A8 UGT1A7

1.13e-04144364GO:0006720
GeneOntologyBiologicalProcessestrogen receptor signaling pathway

LATS1 CNOT2 DDX5

1.34e-0457363GO:0030520
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

LATS1 CLOCK CNOT2 DDX5

1.50e-04155364GO:0043401
GeneOntologyBiologicalProcessregulation of hormone levels

LRP1 UGT1A9 CHD7 CLOCK UGT1A10 UGT1A8 UGT1A7

1.54e-04684367GO:0010817
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

BMPR1A CHD7 LATS1 NCAPG2 CNOT2 MED12 GAB1 NR5A2

1.61e-04929368GO:0009792
GeneOntologyBiologicalProcessaorta development

LRP1 BMPR1A CHD7

3.66e-0480363GO:0035904
GeneOntologyBiologicalProcessventricular trabecula myocardium morphogenesis

BMPR1A CHD7

3.96e-0417362GO:0003222
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

LATS1 CLOCK CNOT2 DDX5

4.11e-04202364GO:0141193
GeneOntologyBiologicalProcessliver development

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.11e-04202364GO:0001889
GeneOntologyBiologicalProcesshepaticobiliary system development

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.35e-04205364GO:0061008
GeneOntologyBiologicalProcesslipid catabolic process

LRP1 UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.99e-04382365GO:0016042
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

BMPR1A CHD7 NFAT5 CLOCK SS18 CREBBP MED12 SS18L1 NR5A2

4.99e-041390369GO:0045944
GeneOntologyBiologicalProcessin utero embryonic development

BMPR1A CHD7 LATS1 NCAPG2 CNOT2 GAB1

5.28e-04596366GO:0001701
GeneOntologyBiologicalProcessglandular epithelial cell differentiation

PAX4 CLOCK NR5A2

5.34e-0491363GO:0002067
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 BMPR1A CHD7

5.51e-0492363GO:0048844
GeneOntologyBiologicalProcesscopper ion transport

CP HEPH

5.52e-0420362GO:0006825
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.87e-04222364GO:0071466
GeneOntologyBiologicalProcessresponse to hepatocyte growth factor

CREBBP GAB1

6.09e-0421362GO:0035728
GeneOntologyBiologicalProcesscardiac right ventricle morphogenesis

BMPR1A CHD7

6.09e-0421362GO:0003215
GeneOntologyBiologicalProcessembryo development

BMPR1A CHD7 LATS1 CREBBP NCAPG2 CNOT2 MED12 GAB1 NR5A2

6.36e-041437369GO:0009790
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

LATS1 CLOCK CNOT2 DDX5 NR5A2

7.34e-04416365GO:0030522
GeneOntologyBiologicalProcesspancreas development

PAX4 CLOCK NR5A2

7.45e-04102363GO:0031016
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

LATS1 CLOCK CNOT2 DDX5

7.74e-04239364GO:0071383
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 VPS13A

7.98e-0424362GO:1905146
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

LRP1 BMPR1A LATS1 SS18 CREBBP GAB1 DDX5 VPS13A

8.33e-041186368GO:0007167
GeneOntologyBiologicalProcesschordate embryonic development

BMPR1A CHD7 LATS1 NCAPG2 CNOT2 MED12 GAB1

8.42e-04906367GO:0043009
GeneOntologyBiologicalProcessdevelopmental growth

LRP1 BMPR1A CHD7 LATS1 NCAPG2 MED12 VPS13A

8.70e-04911367GO:0048589
GeneOntologyBiologicalProcesssister chromatid segregation

LATS1 ANAPC5 NCAPG2 STAG2

9.71e-04254364GO:0000819
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 BMPR1A LATS1 CREBBP DDX5

9.93e-04445365GO:0141091
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 VPS13A

1.09e-0328362GO:0007039
GeneOntologyBiologicalProcesschromosome segregation

LATS1 HAUS2 ANAPC5 NCAPG2 STAG2

1.21e-03465365GO:0007059
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

LRP1 BMPR1A LATS1 CREBBP

1.32e-03276364GO:0007179
GeneOntologyBiologicalProcesspositive regulation of chromosome separation

ANAPC5 NCAPG2

1.33e-0331362GO:1905820
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 BMPR1A LATS1 CREBBP DDX5

1.42e-03482365GO:0007178
GeneOntologyBiologicalProcesscellular response to hormone stimulus

LATS1 CLOCK CNOT2 GAB1 DDX5 NR5A2

1.48e-03727366GO:0032870
GeneOntologyBiologicalProcesshormone metabolic process

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.50e-03286364GO:0042445
GeneOntologyBiologicalProcessartery development

LRP1 BMPR1A CHD7

1.60e-03133363GO:0060840
GeneOntologyBiologicalProcesscardiac septum development

LRP1 BMPR1A CHD7

1.64e-03134363GO:0003279
GeneOntologyBiologicalProcessregulation of intracellular estrogen receptor signaling pathway

LATS1 CNOT2

1.80e-0336362GO:0033146
GeneOntologyBiologicalProcessheart trabecula morphogenesis

BMPR1A CHD7

2.00e-0338362GO:0061384
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

UGT1A9 SS18 UGT1A10 UGT1A8 UGT1A7

2.06e-03525365GO:0009410
GeneOntologyBiologicalProcessembryonic limb morphogenesis

BMPR1A CHD7 CREBBP

2.17e-03148363GO:0030326
GeneOntologyBiologicalProcessembryonic appendage morphogenesis

BMPR1A CHD7 CREBBP

2.17e-03148363GO:0035113
GeneOntologyBiologicalProcessnegative regulation of intracellular steroid hormone receptor signaling pathway

CLOCK CNOT2

2.22e-0340362GO:0033144
GeneOntologyBiologicalProcesstype B pancreatic cell differentiation

PAX4 CLOCK

2.44e-0342362GO:0003309
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

LRP1 BMPR1A LATS1 CREBBP

2.70e-03336364GO:0071560
GeneOntologyBiologicalProcessendocrine system development

BMPR1A PAX4 CLOCK

2.76e-03161363GO:0035270
GeneOntologyBiologicalProcesscolumnar/cuboidal epithelial cell differentiation

PAX4 CLOCK NR5A2

2.91e-03164363GO:0002065
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

LRP1 BMPR1A LATS1 CREBBP

2.91e-03343364GO:0071559
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 BMPR1A LATS1 CREBBP

3.03e-03347364GO:0090092
HumanPhenoFrontal cortical atrophy

SCYL2 GRIA3 VPS13A

6.67e-0612173HP:0006913
HumanPhenoSelf-mutilation

GRIA3 CHD7 CREBBP VPS13A

1.93e-0551174HP:0000742
HumanPhenoTrichiasis

CREBBP NCAPG2

6.27e-054172HP:0001128
MousePhenodecreased circulating luteinizing hormone level

CHD7 LATS1 CLOCK

9.34e-0621283MP:0002773
MousePhenodecreased luteinizing hormone level

CHD7 LATS1 CLOCK

3.43e-0532283MP:0005132
MousePhenodecreased red blood cell distribution width

CHD7 CLOCK OPLAH

8.42e-0543283MP:0010068
DomainUDPGT

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.80e-0821364PS00375
DomainUDPGT

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.80e-0821364PF00201
DomainUDP_glucos_trans

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.80e-0821364IPR002213
DomainMULTICOPPER_OXIDASE2

CP HEPH

1.08e-053362PS00080
DomainCu-oxidase

CP HEPH

1.08e-053362PF00394
DomainSSXT

SS18 SS18L1

1.08e-053362PF05030
DomainSS18_fam

SS18 SS18L1

1.08e-053362IPR007726
DomainCu-oxidase

CP HEPH

1.08e-053362IPR001117
DomainCu-oxidase_2

CP HEPH

2.16e-054362IPR011706
DomainCu-oxidase_2

CP HEPH

2.16e-054362PF07731
DomainCu-oxidase_3

CP HEPH

3.60e-055362IPR011707
DomainCu_oxidase_CS

CP HEPH

3.60e-055362IPR033138
DomainMULTICOPPER_OXIDASE1

CP HEPH

3.60e-055362PS00079
DomainCu-oxidase_3

CP HEPH

3.60e-055362PF07732
DomainCu_oxidase_Cu_BS

CP HEPH

5.39e-056362IPR002355
Domain-

CP HEPH

3.24e-04143622.60.40.420
DomainCupredoxin

CP HEPH

8.14e-0422362IPR008972
DomainARM-like

SCYL2 NCAPG2 STAG2 MED12

1.75e-03270364IPR011989
DomainHEAT

SCYL2 NCAPG2

3.85e-0348362PF02985
DomainHEAT

SCYL2 NCAPG2

5.58e-0358362IPR000357
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A9 CP UGT1A10 UGT1A8 UGT1A7

3.07e-0841325M7399
PathwayWP_ESTROGEN_METABOLISM

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.55e-0722324MM15888
PathwayREACTOME_GLUCURONIDATION

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.25e-0724324MM14599
PathwayREACTOME_GLUCURONIDATION

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.67e-0725324M17787
PathwayWP_GLUCURONIDATION

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.67e-0725324MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.67e-0725324M605
PathwayWP_GLUCURONIDATION

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.16e-0726324M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.31e-0728324M19580
PathwayREACTOME_PARACETAMOL_ADME

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.70e-0639324MM15695
PathwayREACTOME_ASPIRIN_ADME

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.05e-0645324MM15694
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A9 UGT1A10 UGT1A8

3.80e-0614323M39328
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

3.92e-06107325MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

4.30e-06109325M18788
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.07e-0651324M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.48e-0652324M14171
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.88e-0655324M14933
PathwayKEGG_RETINOL_METABOLISM

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.26e-0564324M9488
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.80e-0570324M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.02e-0572324M9257
PathwayREACTOME_DRUG_ADME

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.03e-04109324M45012
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

TYR SS18 SS18L1

1.15e-0442323M48237
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

PAX4 CREBBP NR5A2

1.15e-0442323M17541
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

1.24e-04219325MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

1.26e-04220325M10320
PathwayREACTOME_ASPIRIN_ADME

UGT1A9 UGT1A8 UGT1A7

1.32e-0444323M45014
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

UGT1A9 CLOCK CREBBP MED12

1.40e-04118324M27316
PathwayREACTOME_DRUG_ADME

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.45e-04119324MM15692
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

TYR SS18 CREBBP SS18L1

2.49e-04137324M48232
PathwayWP_2Q37_COPY_NUMBER_VARIATION_SYNDROME

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.09e-04145324M45512
PathwayWP_IRINOTECAN_PATHWAY

UGT1A9 UGT1A10

3.25e-0412322M39611
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

CREBBP STAG2 DDX5 NR5A2

3.42e-04149324M27888
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.79e-04153324MM15844
PathwayWP_RUBINSTEINTAYBI_SYNDROME_1

CLOCK CREBBP

5.15e-0415322M48323
PathwayWP_IRON_METABOLISM_DISORDERS

CP HEPH

6.65e-0417322M48053
PathwayREACTOME_SUMOYLATION

CREBBP STAG2 DDX5 NR5A2

8.39e-04189324M27214
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

TYR PAX4 SS18 CREBBP CNOT2 MED12 GAB1 TLN1 SS18L1 NR5A2

9.01e-0414323210M509
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

CP HEPH

9.25e-0420322MM15077
PathwayWP_TAMOXIFEN_METABOLISM

UGT1A10 UGT1A8

1.02e-0321322M39631
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TYR SS18 SS18L1

1.28e-0395323M48268
PathwayREACTOME_METAL_ION_SLC_TRANSPORTERS

CP HEPH

1.34e-0324322M18795
PathwayWP_ESTROGEN_METABOLISM_WP5276

UGT1A10 UGT1A8

1.34e-0324322M46445
PathwayKEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG

PAX4 NR5A2

1.45e-0325322M18312
PathwayREACTOME_ESR_MEDIATED_SIGNALING

CREBBP STAG2 DDX5 NR5A2

1.47e-03220324M27794
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

CLOCK CREBBP

1.69e-0327322M26943
PathwayREACTOME_PARACETAMOL_ADME

UGT1A9 UGT1A10

1.95e-0329322M45015
PathwayKEGG_CELL_CYCLE

ANAPC5 CREBBP STAG2

2.80e-03125323M7963
PathwayPID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY

GAB1 TLN1

2.83e-0335322M127
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.45e-11636432527940
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.45e-11636420297805
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.38e-1173648467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.38e-1173648464825
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.38e-11736427514509
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.75e-11836417179145
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.75e-11836420610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.75e-11836418052087
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.21e-10936422511988
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.02e-101036423642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.02e-101036411465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.02e-101036423371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.02e-101036422558097
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.76e-101236420308471
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.76e-101236419419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.76e-101236411434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.86e-101336422085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.86e-101336425246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.60e-101436421646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.60e-101436410836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.60e-101436414672974
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.60e-10143649295054
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A9 UGT1A10 UGT1A8

1.02e-09336329519853
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A9 UGT1A10 UGT1A8

1.02e-09336312847094
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.74e-091636419414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.28e-091736420639394
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.93e-091836420056724
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

3.58e-095736521886157
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.70e-091936423281178
Pubmed

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

UGT1A9 UGT1A10 UGT1A7

4.07e-09436317558305
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.01e-082436424625756
Pubmed

Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

UGT1A9 UGT1A8 UGT1A7

1.02e-08536320565459
Pubmed

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

UGT1A9 UGT1A10 UGT1A8

1.02e-08536315057901
Pubmed

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.

UGT1A9 UGT1A10 UGT1A8

8.52e-08936320732626
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A9 UGT1A8 UGT1A7

1.67e-071136318695635
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.65e-076636419898482
Pubmed

Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.

CP HEPH

1.04e-06236218326691
Pubmed

Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain.

CP HEPH

1.04e-06236225788583
Pubmed

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

UGT1A9 UGT1A10

1.04e-06236225547628
Pubmed

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.

CP HEPH

1.04e-06236215365174
Pubmed

Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.

CP HEPH

1.04e-06236230060949
Pubmed

Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.

CP HEPH

1.04e-06236229883959
Pubmed

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.

UGT1A10 UGT1A8

1.04e-06236211901093
Pubmed

Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.

CP HEPH

1.04e-06236222342521
Pubmed

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.

UGT1A9 UGT1A7

1.04e-06236211677206
Pubmed

The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration.

CP HEPH

1.04e-06236221051716
Pubmed

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

UGT1A9 UGT1A10

1.04e-06236222031623
Pubmed

Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.

CP HEPH

1.04e-06236226303407
Pubmed

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

UGT1A10 UGT1A8

1.04e-06236210497143
Pubmed

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

UGT1A9 UGT1A8

1.04e-06236218568343
Pubmed

Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.

CP HEPH

1.04e-06236229355933
Pubmed

Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.

UGT1A10 UGT1A8

1.04e-06236217603215
Pubmed

Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney.

CP HEPH

1.04e-06236227991585
Pubmed

UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.

UGT1A9 UGT1A7

1.04e-06236215709193
Pubmed

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.

UGT1A9 UGT1A7

1.04e-06236212944498
Pubmed

Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.

UGT1A10 UGT1A8

1.04e-0623629647757
Pubmed

Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

UGT1A9 UGT1A7

1.04e-06236217529886
Pubmed

How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?

UGT1A9 UGT1A10

1.04e-06236220089735
Pubmed

Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci.

SS18 SS18L1

1.04e-06236216484776
Pubmed

Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.

CP HEPH

1.04e-06236217065470
Pubmed

Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes.

CP HEPH

1.04e-06236231263155
Pubmed

An atlas of genetic influences on human blood metabolites.

UGT1A9 UGT1A10 UGT1A8 UGT1A7 OPLAH

1.52e-0619036524816252
Pubmed

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.

UGT1A9 CREBBP UGT1A10 UGT1A8 UGT1A7

2.10e-0620336516916647
Pubmed

Discovery and refinement of loci associated with lipid levels.

LRP1 UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.54e-0621136524097068
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP SS18L1

3.12e-06336214716005
Pubmed

Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.

CP HEPH

3.12e-06336230182051
Pubmed

Mediator modulates Gli3-dependent Sonic hedgehog signaling.

CREBBP MED12

3.12e-06336217000779
Pubmed

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

UGT1A9 UGT1A7

3.12e-06336219364970
Pubmed

Iron promotes oxidative cell death caused by bisretinoids of retina.

CP HEPH

3.12e-06336229686088
Pubmed

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

UGT1A9 UGT1A7

3.12e-06336216636344
Pubmed

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

UGT1A9 UGT1A10

3.12e-06336220007669
Pubmed

Genetic polymorphisms of UGT1A8, UGT1A9 and HNF-1α and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid.

UGT1A9 UGT1A8

3.12e-06336223721685
Pubmed

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

UGT1A10 UGT1A8

3.12e-06336219244109
Pubmed

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

UGT1A9 UGT1A8

3.12e-06336226247833
Pubmed

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.

UGT1A9 UGT1A8

3.12e-06336217339869
Pubmed

Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.

UGT1A9 UGT1A7

3.12e-06336224453052
Pubmed

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.

UGT1A9 UGT1A8

3.12e-06336219225446
Pubmed

[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].

UGT1A9 UGT1A7

3.12e-06336223789755
Pubmed

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.

NFAT5 DDX5

3.12e-06336222266867
Pubmed

Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux.

CP HEPH

3.12e-06336223640881
Pubmed

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.

UGT1A9 UGT1A7

3.12e-06336217406868
Pubmed

[Ceruloplasmin, hephaestin and zyklopen: the three multicopper oxidases important for human iron metabolism].

CP HEPH

3.12e-06336224988611
Pubmed

Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin.

CP HEPH

3.12e-06336218022819
Pubmed

Targeted disruption of the synovial sarcoma-associated SS18 gene causes early embryonic lethality and affects PPARBP expression.

SS18 SS18L1

3.12e-06336216926188
Pubmed

Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.

UGT1A8 UGT1A7

3.12e-06336219996319
Pubmed

Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

UGT1A9 UGT1A8

3.12e-06336216397224
Pubmed

Mapping and characterization of the mouse and human SS18 genes, two human SS18-like genes and a mouse Ss18 pseudogene.

SS18 SS18L1

3.12e-06336211435705
Pubmed

Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis.

CP HEPH

3.12e-06336235271829
Pubmed

Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients.

UGT1A9 UGT1A8

6.24e-06436218946804
Pubmed

Sumoylation controls CLOCK-BMAL1-mediated clock resetting via CBP recruitment in nuclear transcriptional foci.

CLOCK CREBBP

6.24e-06436226164627
Pubmed

CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription.

CLOCK CREBBP

6.24e-06436219922678
Pubmed

Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.

UGT1A9 UGT1A8

6.24e-06436220147615
Pubmed

Mice with hepcidin-resistant ferroportin accumulate iron in the retina.

CP HEPH

6.24e-06436226506980
Pubmed

Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300.

CREBBP DDX5

6.24e-06436212527917
Pubmed

Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1.

CLOCK CREBBP

6.24e-06436216606840
Pubmed

UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy.

UGT1A9 UGT1A7

6.24e-06436220628391
Pubmed

Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue.

UGT1A10 UGT1A7

6.24e-0643629271343
Pubmed

Genetic polymorphisms of UGT1A8, UGT1A9, UGT2B7 and ABCC2 in Chinese renal transplant recipients and a comparison with other ethnic populations.

UGT1A9 UGT1A8

6.24e-06436223700788
Pubmed

Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.

UGT1A9 UGT1A10

6.24e-0643622108603
Pubmed

Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice.

CP HEPH

6.24e-06436220811044
InteractionUGT1A9 interactions

UGT1A9 UGT1A10 UGT1A7

1.48e-0613363int:UGT1A9
InteractionUGT1A7 interactions

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.17e-0657364int:UGT1A7
InteractionUGT1A8 interactions

UGT1A8 UGT1A7

9.30e-063362int:UGT1A8
InteractionUGT1A10 interactions

UGT1A9 UGT1A10 UGT1A7

2.75e-0533363int:UGT1A10
InteractionERG interactions

CHD7 SS18 CREBBP SS18L1 DDX5

4.52e-05223365int:ERG
InteractionTBXT interactions

CHD7 SS18 CREBBP SS18L1

5.32e-05116364int:TBXT
InteractionPAX7 interactions

CHD7 SS18 CREBBP SS18L1

6.91e-05124364int:PAX7
InteractionCREBBP interactions

GRIA3 LATS1 CLOCK ANAPC5 CREBBP SS18L1 DDX5

7.80e-05599367int:CREBBP
Cytoband2q37

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.87e-09313642q37
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.98e-05226364chr2q37
CytobandXq25

GRIA3 STAG2

4.81e-0441362Xq25
CytobandEnsembl 112 genes in cytogenetic band chrXq25

GRIA3 STAG2

6.59e-0448362chrXq25
GeneFamilyUDP glucuronosyltransferases

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.96e-0832254363
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CLOCK CREBBP

2.46e-0417252486
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 CLOCK ANAPC5 CNOT2 GAB1

4.10e-071883656468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 CLOCK ANAPC5 CNOT2 GAB1

4.10e-071883657a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LATS1 CLOCK ANAPC5 CNOT2 GAB1

4.10e-071883659cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_2|COVID-19_Convalescent / Disease condition and Cell class

LRP1 HLA-DMA TLN1 DDX5

1.92e-05198364f65fd9b773aeafa55e38309479954a8e41371f52
Drugnaringenin chalcone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.63e-115364ctd:C027329
Druganthrarobin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.63e-115364ctd:C032186
Drug1,2,5,8-tetrahydroxy anthraquinone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.88e-116364ctd:C543211
Drugalloin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.88e-116364ctd:C006457
Drug3-phenylpropionic acid

TYR UGT1A10 UGT1A8 UGT1A7

7.88e-116364ctd:C035253
Drug2',5'-dihydroxychalcone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.88e-116364ctd:C107497
Drugalmokalant

UGT1A9 UGT1A10 UGT1A8 UGT1A7 HEPH

8.47e-1119365CID003033962
Drug2',4'-dihydroxychalcone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.84e-107364ctd:C059354
Drug1,4-dihydroxyanthraquinone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.67e-108364ctd:C034890
Drug5-MOP

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.84e-1025365CID000002355
DrugAC1MRQNQ

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.59e-109364CID003522271
DrugDHPASiU

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.59e-109364CID000197602
DrugChebi:32663

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.59e-109364CID005460873
Drug3-iodophenol

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.59e-109364CID000012272
DrugAC1L4J7U

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.59e-109364CID000186631
Drug2,6-dihydroxyanthraquinone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.10e-0910364ctd:C034889
DrugPCB 156

UGT1A9 HLA-DMA UGT1A10 UGT1A8 UGT1A7

1.22e-0931365CID000038019
Drugindole-2-carboxylic acid

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.44e-0932365CID000072899
Druggeniposide

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.70e-0933365CID000107848
Drug4-nitrophenyl)imidazole

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.72e-0911364CID000123155
DrugAC1O5XMV

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.72e-0911364CID006442661
DrugN-OH-DABZ

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364CID000088735
Drug4-hydroxyestrone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364ctd:C026418
Drug2,4,6-TCB

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364CID000037247
Drug7,7,7-triphenylheptanoic acid

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364CID000276709
Drugnonanoyl-N-methylglucamide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.58e-0912364CID000160090
Drug2-hydroxyestrone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.72e-0913364ctd:C024980
Drugtritanol

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.72e-0913364CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.72e-0913364CID003081279
Drugcotinine-N-glucuronide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.72e-0913364CID000000411
Drugalizarin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.72e-0913364ctd:C010078
Drugpropranolol glucuronide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.21e-0914364CID000119515
DrugPCB-61

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.21e-0914364CID000036401
DrugPTBP

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.03e-0942365CID000007393
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364CID000040469
Drugcoumarin-3-carboxylic acid

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364CID000010752
Drugbergamottin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364ctd:C068337
Drugsulforaphane nitrile

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364CID000543743
Drugafloqualone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364CID000002040
Drugnaphthyl sulphate

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.09e-0915364CID000114775
Drugquercetin-3,4'-diglucoside

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.45e-0916364CID005320835
Drug1'-hydroxyestragole

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.45e-0916364CID000040003
Drugbilirubin-phosphate

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.45e-0916364CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.23e-0817364CID000003573
Drug6-hydroxychrysene

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.23e-0817364CID000037766
DrugEM-652

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.34e-0849365CID000155435
Drug2-vanillin

UGT1A10 UGT1A8 UGT1A7

1.45e-084363ctd:C060843
Drughydratropic acid

UGT1A10 UGT1A8 UGT1A7

1.45e-084363ctd:C013025
Drugdiphenylacetic acid

UGT1A10 UGT1A8 UGT1A7

1.45e-084363ctd:C037760
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID000152226
DrugBr 2

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID003060900
DrugSureCN12722713

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID005488034
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID000036614
DrugApApG

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID003081975
DrugC1 11-32

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID000443077
DrugC11131

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.59e-0818364CID000443076
Drug9-OH-risperidone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.01e-0819364CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.01e-0819364CID000091433
Drugtectochrysin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.50e-0820364CID005281954
DrugAC1L1OBF

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.50e-0820364CID000032736
Drug4'-hydroxydiclofenac

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.50e-0820364CID000116545
Drugentacapone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.50e-0820364ctd:C071192
DrugInvader

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.67e-0856365CID006442259
Drugestriol-16-glucuronide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.09e-0821364CID000122281
Drugdulcin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.09e-0821364CID000009013
DrugBenzamidoxime hydrochloride

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.09e-0821364CID000069186
Drugmorin

UGT1A9 CP UGT1A10 UGT1A8 UGT1A7

3.19e-0858365ctd:C008548
Drugisovaleric acid

UGT1A10 UGT1A8 UGT1A7

3.62e-085363ctd:C008216
Drugbiphenylylacetic acid

UGT1A10 UGT1A8 UGT1A7

3.62e-085363ctd:C012776
Drugamonafide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.77e-0822364CID000050515
Drugplumbagin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.77e-0822364ctd:C014758
DrugN-methylpiperazine

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.77e-0822364CID000053167
Drugamidoxime

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.56e-0823364CID000465967
Drugestradiol-3-glucuronide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.56e-0823364CID000066651
Drugphenanthridine

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.56e-0823364CID000009189
Drug2-hydroxyestradiol

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.87e-0863365CID000009684
Drugcinnamic acid

TYR UGT1A10 UGT1A8 UGT1A7

5.47e-0824364ctd:C029010
DrugAS-3201

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.47e-0824364CID000153948
Drugethoxytriethyleneglycol

UGT1A9 GRIA3 UGT1A10 UGT1A8 UGT1A7

6.17e-0866365CID000008190
DrugHymecromone

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.50e-0825364ctd:D006923
DrugAzMC

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.50e-0825364CID000064986
DrugN-acetylbenzidine

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.50e-0825364CID000018787
Drug5,6-benzoquinoline

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.50e-0825364CID000006796
DrugN-phenylmaleimide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.50e-0825364CID000013662
Druggalangin

TYR UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.18e-0868365ctd:C037032
DrugIndoprofen

UGT1A10 UGT1A8 UGT1A7

7.24e-086363ctd:D007216
DrugThymol

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.67e-0826364ctd:D013943
DrugScopoletin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.00e-0827364ctd:D012603
DrugDiMeIQx

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.00e-0827364CID000104739
Druglicochalcone A

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.00e-0827364ctd:C070840
Drugdiflunisal

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.00e-0827364CID000003059
DrugN-hydroxy-4-aminobiphenyl

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.05e-0728364CID000081261
DrugCARMINE

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.05e-0728364CID000014749
Drugerucin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.05e-0728364CID000078160
DrugH-Ni

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.05e-0728364CID000445665
DrugAC1L1JAL

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.22e-0729364CID000004954
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.22e-0729364CID005375667
Drugtrans-3'-hydroxycotinine

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.22e-0729364CID000000414
Drug7-hydroxycoumarin glucuronide

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.22e-0729364CID000125641
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.32e-125364EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.32e-125364EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.32e-125364EFO_0801853
DiseaseX-21339 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.51e-117364EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0021260
DiseaseSuccinimide measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0022118
DiseaseX-11530 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0800696
DiseaseX-10458 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0800692
DiseaseX-24849 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0600043
Diseaseplasma clozapine measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0802740
DiseaseX-16946 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.30e-108364EFO_0800766
DiseaseX-11442 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0021236
DiseaseX-11441 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0004739
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0801036
DiseaseX-11880 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

2.34e-109364EFO_0020691
DiseaseX-21448 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.90e-1010364EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.90e-1010364EFO_0802185
DiseaseX-23974 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.90e-1010364EFO_0800867
Diseasebilirubin measurement, response to tenofovir

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.90e-1010364EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0800825
Diseasepregnenetriol sulfate measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0600039
Diseaseinsomnia, bilirubin measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0800972
Diseasealdosterone measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

6.12e-1011364EFO_0010219
Diseasebiliverdin measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.17e-1012364EFO_0021033
Diseasep-cresol glucuronide measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

9.17e-1012364EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.32e-0913364EFO_0802007
Diseasepregnenetriol disulfate measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.32e-0913364EFO_0800587
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A9 UGT1A10 UGT1A8

1.67e-093363EFO_0022216
Diseaseindole-3-carboxylate measurement

UGT1A9 UGT1A10 UGT1A8

1.67e-093363EFO_0800043
DiseaseX-21441 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.39e-0917364EFO_0800814
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.39e-0917364EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.64e-0918364EFO_0801382
Diseasetissue factor measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.10e-0821364EFO_0010623
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A9 UGT1A10 UGT1A8

3.33e-086363EFO_0800566
Diseaseneuroblastoma, cutaneous melanoma

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.74e-0828364EFO_0000389, EFO_0000621
Diseasexanthurenate measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

4.34e-0829364EFO_0010551
Diseaseresponse to dolutegravir

UGT1A9 UGT1A10 UGT1A8 UGT1A7

5.00e-0830364EFO_0600017
Diseasecholelithiasis

UGT1A9 NFAT5 UGT1A10 UGT1A8 UGT1A7

7.37e-0888365EFO_0004799
Diseasevitamin D deficiency

UGT1A9 UGT1A10 UGT1A8 UGT1A7

1.20e-0737364EFO_0003762
Diseaseindoleacetate measurement

UGT1A9 UGT1A10 UGT1A8

1.99e-0710363EFO_0021015
Diseasegallstones

UGT1A9 NFAT5 UGT1A10 UGT1A8 UGT1A7

2.06e-07108365EFO_0004210
Diseasevitamin D measurement, COVID-19

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.80e-0749364EFO_0004631, MONDO_0100096
DiseaseX-24588 measurement

UGT1A9 UGT1A10 UGT1A8

4.73e-0713363EFO_0800898
Diseaseurate measurement, spine bone mineral density

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.55e-0758364EFO_0004531, EFO_0007701
Diseasethyroxine measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.20e-0683364EFO_0005130
Diseasehormone measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.36e-0684364EFO_0004730
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A9 UGT1A10 UGT1A8 UGT1A7

3.08e-05147364DOID:9352 (biomarker_via_orthology)
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

GRIA3 CREBBP SS18L1

3.14e-0550363C1862939
Diseasefree androgen index

UGT1A9 CHD7 UGT1A10 UGT1A8 UGT1A7

8.69e-05374365EFO_0007005
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

9.48e-0512362EFO_0021054
Diseaseurate measurement, bone density

SCYL2 UGT1A9 BMPR1A UGT1A10 UGT1A8 UGT1A7

9.48e-05619366EFO_0003923, EFO_0004531
Diseaseserum gamma-glutamyl transferase measurement

UGT1A9 SLC25A30 ANAPC5 UGT1A10 UGT1A8 UGT1A7 TLN1

1.02e-04914367EFO_0004532
Diseasemelanoma

TYR CP PAX4 STAG2

2.32e-04248364C0025202
Diseasediabetes mellitus (implicated_via_orthology)

LRP1 CLOCK

4.62e-0426362DOID:9351 (implicated_via_orthology)
DiseasePigmented Basal Cell Carcinoma

TYR LATS1

5.36e-0428362C1368275
Diseasemetabolite measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7 NR5A2

5.61e-04560365EFO_0004725
DiseaseCarcinoma, Basal Cell

TYR LATS1

5.76e-0429362C4721806
DiseaseSchizophrenia

LRP1 TYR GRIA3 CP CLOCK MED12

6.38e-04883366C0036341
Diseasevitamin D measurement

UGT1A9 UGT1A10 UGT1A8 UGT1A7

7.30e-04336364EFO_0004631
Diseasetestosterone measurement

UGT1A9 CHD7 SS18 UGT1A10 UGT1A8 MED12 UGT1A7

7.68e-041275367EFO_0004908
DiseaseCarcinoma, Transitional Cell

CREBBP STAG2

1.15e-0341362C0007138

Protein segments in the cluster

PeptideGeneStartEntry
MAGGMAGHGQFQQPQ

CREBBP

2221

Q92793
GDFSMQQHGQPQQRM

CHD7

196

Q9P2D1
NPMMTNGVVHANVFG

ANAPC5

11

Q9UJX4
INGRMFGNLQGLTMH

CP

961

P00450
GHFIASGMVNQEMLN

HAUS2

21

Q9NVX0
GMQNGTGQTDFMIHQ

LATS1

346

O95835
SQSKHGMNGFFQQQM

GAB1

226

Q13480
HQRMTNGAMNVEIGN

LRP1

4456

Q07954
QYGSNVPNMHNGMNQ

DDX5

576

P17844
MHGGANITGFQIVNN

GRIA3

261

P42263
QQSQGMLGQSSVHQM

MED12

1916

Q93074
QGNGLFQQGNEMMSL

NFAT5

1041

O94916
MHQDGISSMNQLGGL

PAX4

1

O43316
AQSNTIQGGMIGNFM

SLC25A30

136

Q5SVS4
IQGGMIGNFMNIYQQ

SLC25A30

141

Q5SVS4
VQGQNLDSMLHGTGM

BMPR1A

21

P36894
MGHEQNQGAALLQML

HLA-DMA

1

P28067
HNAAFMQIPMGLEGN

GFM1

196

Q96RP9
HGEQGQMPENMQVSQ

NR5A2

56

O00482
PALQQTMQAMLHFGG

RUSC1

686

Q9BVN2
QGCMNNVTLGNAHMG

OPLAH

1101

O14841
HGVMFQGNTVQLQGM

HEPH

656

Q9BQS7
VMGTQMNVIGQSAFG

SCYL2

881

Q6P3W7
MNVIGQSAFGMQGNP

SCYL2

886

Q6P3W7
IQEQLQMVHGQGLQM

CLOCK

551

O15516
QMVHGQGLQMFLQQS

CLOCK

556

O15516
MNTGHIGTTQHMIQQ

CLOCK

611

O15516
VVMVGLGDHQFQMQL

NCAPG2

891

Q86XI2
PRNMMNHSQVGQGIG

CNOT2

136

Q9NZN8
QHYQGQSSIAMMGQG

SS18L1

206

O75177
HDPVMGSQANYGMQQ

ZCCHC2

1086

Q9C0B9
GTGNQMLQVMENGRF

VPS13A

3056

Q96RL7
MPNMIFIGGINCHQG

UGT1A10

266

Q9HAW8
NGHHQQNGVENMMLF

STAG2

71

Q8N3U4
AQQQITSGQMHRGHM

TLN1

471

Q9Y490
GQVNQGNHMMGQRQI

SS18

236

Q15532
LHIYMNGTMSQVQGS

TYR

366

P14679
MPNMIFIGGINCHQG

UGT1A9

266

O60656
MPNMIFIGGINCHQG

UGT1A7

266

Q9HAW7
MPNMIFIGGINCHQG

UGT1A8

266

Q9HAW9