Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainNebulin

NRAP NEB

2.16e-0441132PF00880
DomainNEBULIN

NRAP NEB

2.16e-0441132PS51216
DomainNEBU

NRAP NEB

2.16e-0441132SM00227
DomainNebulin

NRAP NEB

2.16e-0441132IPR013998
DomainNebulin_repeat

NRAP NEB

2.16e-0441132IPR000900
DomainDWB

SMAD3 SMAD9

9.92e-0481132SM00524
DomainMH2

SMAD3 SMAD9

9.92e-0481132PS51076
DomainMH1

SMAD3 SMAD9

9.92e-0481132PS51075
Domain-

SMAD3 SMAD9

9.92e-04811323.90.520.10
DomainMAD_homology_MH1

SMAD3 SMAD9

9.92e-0481132IPR013019
DomainNeurexophilin

NXPE2 NXPH4

9.92e-0481132PF06312
DomainDwarfin

SMAD3 SMAD9

9.92e-0481132IPR013790
DomainNXPH/NXPE

NXPE2 NXPH4

9.92e-0481132IPR026845
DomainMH2

SMAD3 SMAD9

9.92e-0481132PF03166
DomainSMAD_dom_Dwarfin-type

SMAD3 SMAD9

9.92e-0481132IPR001132
DomainTyr_Pase_AS

PTPDC1 PTPN3 MTMR4 PTPRM

1.00e-03731134IPR016130
DomainTYR_PHOSPHATASE_1

PTPDC1 PTPN3 MTMR4 PTPRM

1.84e-03861134PS00383
DomainTYR_PHOSPHATASE_dom

PTPDC1 PTPN3 MTMR4 PTPRM

1.92e-03871134IPR000387
DomainTYR_PHOSPHATASE_2

PTPDC1 PTPN3 MTMR4 PTPRM

1.92e-03871134PS50056
DomainMAD_homology1_Dwarfin-type

SMAD3 SMAD9

2.30e-03121132IPR003619
DomainDWA

SMAD3 SMAD9

2.30e-03121132SM00523
DomainMH1

SMAD3 SMAD9

2.30e-03121132PF03165
DomainDUF4599

SPATA31D4 SPATA31D3

2.30e-03121132PF15371
DomainDUF4599

SPATA31D4 SPATA31D3

2.30e-03121132IPR027970
Domain-

PTPDC1 PTPN3 MTMR4 PTPRM

2.36e-039211343.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPDC1 PTPN3 MTMR4 PTPRM

3.08e-03991134IPR029021
DomainSMAD_FHA_domain

APLF SMAD3 SMAD9

3.84e-03521133IPR008984
DomainSMAD_dom-like

SMAD3 SMAD9

4.12e-03161132IPR017855
Domain-

SMAD3 SMAD9

4.12e-031611322.60.200.10
Domain-

PLPPR5 G6PC2

5.21e-031811321.20.144.10
DomainacidPPc

PLPPR5 G6PC2

5.21e-03181132SM00014
DomainPTPc_motif

PTPDC1 PTPN3 PTPRM

5.48e-03591133SM00404
DomainTyr_Pase_cat

PTPDC1 PTPN3 PTPRM

5.48e-03591133IPR003595
Pubmed

Topologically associating domain boundaries are required for normal genome function.

SIM1 SMAD3 TBX5

7.98e-0612117337081156
Pubmed

Immunohistochemical demonstration of EphA2 processing by MT1-MMP in invasive cutaneous squamous cell carcinoma.

EPHA2 MMP14

1.12e-052117227056569
Pubmed

Induction of the MMP-14 gene in macrophages of the atherosclerotic plaque: role of SAF-1 in the induction process.

MAZ MMP14

1.12e-052117215528467
Pubmed

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.

EPHA2 MMP14

1.12e-052117223629968
Pubmed

Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein.

EPHA2 MMP14

1.12e-052117226130649
Pubmed

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.

ANKRD11 SMAD3 SMAD9

1.31e-0514117338951500
Pubmed

β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis.

MMP14 SMAD3 SMAD9

2.92e-0518117328763805
Pubmed

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

SPHKAP EPAS1

3.36e-053117218055454
Pubmed

Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.

MMP14 EPAS1

3.36e-053117217140440
Pubmed

The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis.

ESCO2 TBX5

3.36e-053117231388035
Pubmed

Impaired glycolytic metabolism causes chondrocyte hypertrophy-like changes via promotion of phospho-Smad1/5/8 translocation into nucleus.

SMAD3 SMAD9

3.36e-053117223384547
Pubmed

Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.

TSC2 SMAD3

3.36e-053117215066998
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MYCBP2 DOCK11 MAZ LARP1 TSC2 PRAG1 PTPN3 MTMR4 MAST4 ANKRD11 WNK3 AQR

3.49e-058611171236931259
Pubmed

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.

BCL6 CCNA2 EPAS1 SMAD3

3.90e-0556117430718289
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

VWF NRAP MYCBP2 GON4L BCL6 NEB DNTTIP2 ZNF462 SMAD3

4.88e-05497117923414517
Pubmed

Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.

MYCBP2 TSC2

6.70e-054117214559897
Pubmed

Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin.

SELPLG VWF

6.70e-054117215956287
Pubmed

MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes.

MTMR4 SMAD3

6.70e-054117220061380
Pubmed

[Association of single nucleotide polymorphisms of transcription factors with congenital heart diseases in the Chinese population: a Meta analysis].

ZFPM2 TBX5

6.70e-054117229972125
Pubmed

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha.

MMP14 EPAS1

1.11e-045117223222716
Pubmed

Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.

TSC2 CCNA2

1.11e-045117211444800
Pubmed

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.

LRRC17 TBX5

1.11e-045117227036009
Pubmed

The NADPH oxidase subunit p22phox inhibits the function of the tumor suppressor protein tuberin.

TSC2 EPAS1

1.11e-045117220304964
Pubmed

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

SMAD3 SMAD9

1.11e-045117225141865
Pubmed

Evidence for a role of MSK1 in transforming growth factor-beta-mediated responses through p38alpha and Smad signaling pathways.

RPS6KA5 SMAD3

1.11e-045117215133024
Pubmed

Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.

EPAS1 SMAD3

1.11e-045117221057546
Pubmed

RAIDD is a new 'death' adaptor molecule.

CASP2 TNFRSF1A

1.11e-04511728985253
Pubmed

Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation.

VWF MMP14

1.67e-046117215572153
Pubmed

Smad7 is required for the development and function of the heart.

SMAD3 SMAD9

1.67e-046117218952608
Pubmed

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.

TSC2 CCNA2

1.67e-046117215355997
Pubmed

Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.

SMAD3 SMAD9

1.67e-046117211850197
Pubmed

Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy.

NRAP NEB

1.67e-046117230986853
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MYO5A MYCBP2 EPB41L4B DOCK11 RBMS1 MAZ LARP1 OCRL EPHA2 UNK

1.73e-047241171036232890
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

CASP2 TSC2 BCL6 CCNA2 BHMT TNFRSF1A MMP14

1.93e-04351117720453000
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TPP2 MYO5A MYCBP2 VEZT ZNF174 MAZ ZNF280C PTPDC1 PTPN3 MTMR4 PTPRM SLFN11

2.24e-0410491171227880917
Pubmed

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

SMAD3 SMAD9

2.33e-047117215009097
Pubmed

Ocular abnormalities in mice lacking the immunoglobulin superfamily member Cdo.

CDON TBX5

2.33e-047117219754878
Pubmed

Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C.

UBE2C CCNA2

2.33e-047117231455778
Pubmed

Mutation of an upstream cleavage site in the BMP4 prodomain leads to tissue-specific loss of activity.

SMAD9 TBX5

2.33e-047117216624858
Pubmed

Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

SMAD3 SMAD9

2.33e-047117211163184
Pubmed

Emergence of dorsal-ventral polarity in ESC-derived retinal tissue.

SMAD9 TBX5

2.33e-047117227633992
Pubmed

Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.

MAZ EPAS1

2.33e-047117224891620
Pubmed

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

BCL6 TNFRSF1A

2.33e-047117226728651
Pubmed

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.

UBE2C CCNA2

2.33e-047117227522463
Pubmed

The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.

MYCBP2 TSC2

2.33e-047117222798074
Pubmed

Energy balance, the PI3K-AKT-mTOR pathway genes, and the risk of bladder cancer.

RPS6KA5 TSC2

2.33e-047117220354165
Pubmed

Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.

SLFN11 TNFRSF1A

2.33e-047117215351786
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

MASP1 MYO5A BCL6 TEP1 CCNA2 BHMT TNFRSF1A

2.83e-04374117719625176
Pubmed

Lysine acetylation targets protein complexes and co-regulates major cellular functions.

LARP1 TSC2 PRAG1

2.87e-0438117319608861
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

VWF PDSS1 TSC2 DSCAML1 PTPRM

2.91e-04171117520201926
Pubmed

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension.

SMAD3 SMAD9

3.10e-048117219211612
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD3 SMAD9

3.10e-048117210647776
Pubmed

Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.

NPHP4 TCTN1

3.10e-048117226540106
Pubmed

Cloning, characterization, and genomic structure of the mouse Ikbkap gene.

EPB41L4B PTPN3

3.10e-048117211747609
Pubmed

Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.

SMAD3 SMAD9

3.10e-048117223804438
Pubmed

Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors.

SIM1 EPAS1

3.10e-048117211782478
Pubmed

TGF-beta signaling by Smad proteins.

SMAD3 SMAD9

3.10e-048117210708949
Pubmed

Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.

VWF CCNA2 SMAD3

3.10e-0439117330566624
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

MASP1 MYO5A BCL6 TEP1 CCNA2 BHMT TNFRSF1A

3.17e-04381117718676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

MASP1 MYO5A BCL6 TEP1 CCNA2 BHMT TNFRSF1A

3.22e-04382117719170196
Pubmed

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia.

TSC2 EPAS1 CDON

3.35e-0440117334677125
Pubmed

GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.

SMAD3 SMAD9

3.98e-049117224932701
Pubmed

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases.

CASP2 TNFRSF1A

3.98e-04911729560245
Pubmed

A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.

UBE2C CCNA2

3.98e-049117232307883
Pubmed

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.

SMAD3 SMAD9

3.98e-049117226555259
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD3 SMAD9

3.98e-049117219018011
Pubmed

TGF-beta signal transduction.

SMAD3 SMAD9

3.98e-04911729759503
Pubmed

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

SMAD3 SMAD9

3.98e-049117230134160
Pubmed

Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.

SMAD3 SMAD9

3.98e-049117224816837
Pubmed

Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality.

SMAD9 TBX5

3.98e-049117225428115
Pubmed

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.

SMAD3 SMAD9

3.98e-049117225155999
Pubmed

The Smad pathway.

SMAD3 SMAD9

3.98e-049117210708948
Pubmed

TGF-β signaling inhibits canonical BMP signaling pathway during palate development.

SMAD3 SMAD9

4.96e-0410117229247325
Pubmed

TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration.

VWF TNFRSF1A

4.96e-0410117222972987
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD3 SMAD9

4.96e-0410117223620745
Pubmed

Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein.

EPHA2 TNFRSF1A

4.96e-041011727737295
Pubmed

Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis.

SMAD3 SMAD9

4.96e-0410117229986157
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

TEC PTPN3 PTPRM

5.40e-0447117319167335
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

MASP1 MYO5A BCL6 TEP1 CCNA2 BHMT TNFRSF1A

5.74e-04421117719692168
Pubmed

Wtap is required for differentiation of endoderm and mesoderm in the mouse embryo.

CCNA2 SMAD9

6.05e-0411117218224709
Pubmed

Physical mapping of the autoimmune disease susceptibility locus, Bphs: co-localization with a cluster of genes from the TNF receptor superfamily on mouse chromosome 6.

VWF TNFRSF1A

6.05e-0411117210441735
Pubmed

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

SMAD3 SMAD9

6.05e-0411117227741240
Pubmed

Downregulation of bone morphogenetic protein receptor axis during HIV-1 and cocaine-mediated pulmonary smooth muscle hyperplasia: implications for HIV-related pulmonary arterial hypertension.

SMAD3 SMAD9

6.05e-0411117224008158
Pubmed

Substrate-trapping techniques in the identification of cellular PTP targets.

TEC PTPN3 PTPRM

6.11e-0449117315588985
Pubmed

BMPR-II is dispensable for formation of the limb skeleton.

SMAD3 SMAD9

7.24e-0412117221538804
Pubmed

Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.

SMAD9 TBX5

7.24e-0412117215923624
Pubmed

Smad expression during kidney development.

SMAD3 SMAD9

7.24e-0412117214656760
Pubmed

Regulation of ubiquitin chain initiation to control the timing of substrate degradation.

UBE2C CCNA2

7.24e-0412117221700221
Pubmed

Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.

SMAD3 SMAD9

7.24e-0412117217460146
Pubmed

Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation.

UBE2C CCNA2

7.24e-0412117223007648
Pubmed

Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia.

VWF SMAD3

8.54e-0413117226878215
Pubmed

Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.

SMAD3 SMAD9

8.54e-0413117216959237
Pubmed

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse.

SMAD3 SMAD9

8.54e-0413117218329379
Pubmed

Endoglin is required for myogenic differentiation potential of neural crest stem cells.

SMAD3 SMAD9

8.54e-0413117217628518
Pubmed

Reduced BMP signaling results in hindlimb fusion with lethal pelvic/urogenital organ aplasia: a new mouse model of sirenomelia.

SMAD9 TBX5

9.94e-0414117223028455
Pubmed

Matrix GLA protein, an inhibitory morphogen in pulmonary vascular development.

SMAD3 SMAD9

9.94e-0414117217670744
Pubmed

Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.

UBE2C CCNA2

9.94e-0414117219826003
Pubmed

Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes.

SMAD9 TBX5

9.94e-0414117218985738
Pubmed

Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.

VWF TBX5

9.94e-0414117236347239
Pubmed

Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture.

SMAD3 SMAD9

9.94e-0414117233248111
GeneFamilySMAD family

SMAD3 SMAD9

4.93e-048772750
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFP90 ZNF174 MAZ BCL6 ZNF692 ZNF785 ZUP1 ZFPM2 ZNF462 ZNF792

9.09e-04718771028
CoexpressionZHENG_BOUND_BY_FOXP3

TPP2 VWF AKR1D1 BCL6 TEC PRAG1 ANKRD11 AQR APBB1IP SMAD3 NSMCE1

1.15e-0549811411M1741
CoexpressionZHENG_BOUND_BY_FOXP3

TPP2 VWF AKR1D1 BCL6 TEC PRAG1 ANKRD11 AQR APBB1IP SMAD3 NSMCE1

1.36e-0550711411MM1030
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 DOCK11 DSCAML1 ZNF462 ACSM2A PLS1 APBB1IP

5.88e-071861167f28d72b47624b69a580b4429e2be560a26898591
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

PRPF18 DNTTIP2 MAST4 ELAPOR1 WNK3 TBX5

1.30e-06132116649ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NRAP FAM178B AKR1D1 ASIC3 PLS1

1.46e-06741165a53f2e1f1044f3745a1eff5ba6275c8f1fbf3ae0
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Klk6_(Klk6)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NRAP FAM178B AKR1D1 ASIC3 PLS1

1.46e-06741165ae547cb8bbd780b19d9c6b555c27dad932dcc753
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CFAP47 EPB41L4B ABCA12 SAXO1 OR10G4 WNK3

2.62e-061491166c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CFAP47 EPB41L4B ABCA12 SAXO1 OR10G4 WNK3

2.62e-061491166a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCelldroplet-Fat-Gat-18m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 ESCO2 SPHKAP ENTPD3

4.56e-0616411667dbe34a98a3b475c1ba678db8a5494c0c6a91e2d
ToppCelldroplet-Fat-Gat-18m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 ESCO2 SPHKAP ENTPD3

4.56e-061641166febcb8f8b305aa94e21131fa83d2890f7a6838fc
ToppCelldroplet-Fat-Gat-18m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 ESCO2 SPHKAP ENTPD3

4.72e-0616511661e89154114327650df39befb2c56d0379ea6a221
ToppCellmoderate-Myeloid-Mast_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RPS6KA5 NXPE2 MAST4 ZNF792 WNK3 NSMCE1

6.62e-061751166bbd2971bc6d69e507f90a637834d0936c205c590
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AKR1D1 DSCAML1 ZUP1 ENTPD3 ELAPOR1 UNC13A

7.06e-0617711668abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 VWF UBE2C ZNF280C ZNF785 CCNA2

7.77e-06180116640d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell15-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

CDHR2 FAM178B HEMGN BHMT PRSS21 ACSM2A

9.96e-061881166c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell15-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

CDHR2 FAM178B HEMGN BHMT PRSS21 ACSM2A

9.96e-0618811662534684e4932c1255c24a26ca2277ac7af0a118b
ToppCellfacs-Trachea-nan-3m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG UBE2C HEMGN CCNA2 ESCO2 RASGRP1

1.09e-05191116689eb4e30052d0d4a2952157ca743291900ce8de2
ToppCellfacs-Trachea-nan-3m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG UBE2C HEMGN CCNA2 ESCO2 RASGRP1

1.09e-0519111660bf575eba311745fb75f9523f7fc81f73848e25d
ToppCellfacs-Trachea-nan-3m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG UBE2C HEMGN CCNA2 ESCO2 RASGRP1

1.09e-051911166c57df363e3a6e61d2bdca1955330f1899b964267
ToppCelldroplet-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG MAZ UBE2C CCNA2 RASGRP1 HNRNPLL

1.12e-051921166041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCelldroplet-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG MAZ UBE2C CCNA2 RASGRP1 HNRNPLL

1.12e-051921166d9e61b2722aa81e4f6e11865a04f2f1e75b794ab
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNASE2B KCNMB3 DNAH9 TBX5

1.20e-0554116498b31718fa200432cf86b59a52484da101219f96
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Spp1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DNASE2B KCNMB3 DNAH9 TBX5

1.20e-05541164872e7374dac64be2c8ebe71e88a2ec6814168d89
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HDHD3 FAM178B UBE2C HEMGN CCNA2 WNK3

1.26e-051961166c391d6359634145455c71c7f051bf34ff0eb666d
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SELPLG HDHD3 VWF PTPN3 ZNF792 ENTPD3

1.30e-05197116698f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TEP1 ZNF692 SEC24C KCNMB3 CDON

2.07e-051271165556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

PNLDC1 DNASE2B PRSS21 DNAH9 NXPH4

3.41e-051411165399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MASP1 NRAP FAM178B ASIC3

4.43e-05751164574ed1836f6bf5fa38a53af0a05fa4437f68f36b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr-Oligodendrocyte.Tfr.Slco3a1_(Slco3a1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MASP1 NRAP FAM178B ASIC3

4.43e-0575116445f7861bfeb1c6371b73cf2ea527801342e534bc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 BCL6 ZFPM2 PTPRM CAPS2

4.74e-051511165090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd|lymph-node_spleen / Manually curated celltypes from each tissue

CDHR2 TEP1 PIERCE2 HECTD2 EPAS1

5.36e-051551165b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 SAXO1 DSCAML1 SPHKAP DNAH9

6.23e-051601165c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 SAXO1 DSCAML1 SPHKAP DNAH9

6.23e-05160116525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

CCNA2 IHO1 ESCO2 LRRC17 TBX5

6.81e-0516311658d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

CCNA2 IHO1 ESCO2 LRRC17 TBX5

6.81e-051631165acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCellmoderate-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NXPE2 MAST4 ZNF792 WNK3 NSMCE1

7.42e-051661165c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA5 MYO5A FAM178B TEP1 SMAD3

7.63e-051671165f5bffa77061baec0ba87bd688a047595f32534db
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2C CCNA2 ESCO2 ENTPD3 ELAPOR1

7.63e-051671165a90f905ef38437752e2b0b71bd0322a184de1861
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRAG1 APLF PTPDC1 TEC FDXACB1

8.07e-051691165d721dbb317a88113b4f76688111908d00f23e899
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBE2C HEMGN CCNA2 ESCO2 RASGRP1

8.30e-0517011652d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

UBE2C HEMGN SAXO1 CCNA2 ESCO2

8.30e-0517011655319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

UBE2C PRAG1 CCNA2 ESCO2 SMAD9

8.30e-05170116573601c873b177d5d134618d8e228c51381119f7d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG UBE2C CCNA2 ESCO2 HECTD2

8.30e-051701165a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS6KA5 UBE2C TEC CCNA2 CAPS2

8.53e-0517111656e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

8.53e-051711165ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG DOCK11 TEC DNASE2B APBB1IP

8.77e-0517211656503e85182eb6e8a40a890e393e9ac5c5350e322
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 VWF OCRL ZNF792 EPAS1

8.77e-051721165e359c59631f6a262429b6896a409f2ffbd4f6a76
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

8.77e-05172116595219814e37259e34be053572cc95d4639360c27
ToppCelldroplet-Marrow-BM_(NON-STC)|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

8.77e-0517211656004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

8.77e-05172116531c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELPLG DOCK11 TEC DNASE2B APBB1IP

8.77e-0517211653c0bf7200e582ee730af49dcd86446e112226aca
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

UBE2C SAXO1 CCNA2 ESCO2 TBX5

9.77e-0517611658813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG MYCBP2 DOCK11 RASGRP1 ELAPOR1

9.77e-051761165feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UBE2C HEMGN NPHP4 CCNA2 ESCO2

9.77e-051761165b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1-Tfr|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NRAP FAM178B ASIC3 PLS1

9.84e-059211640754a79efc4c0659d9a2acfe4185bcae1a3e7206
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NRAP FAM178B ASIC3 PLS1

9.84e-05921164aee1fd2419dc1fc7039c0ac56f0ba23ed11d668f
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAM178B UBE2C POF1B CCNA2 ESCO2

1.00e-041771165a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF280C AKR1D1 OCRL NPHP4 UNK

1.03e-0417811659d575902d3dbe33437c9d4200df093a741269803
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.06e-041791165f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.06e-041791165804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.06e-04179116501e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

UBE2C SAXO1 CCNA2 ESCO2 TBX5

1.06e-041791165e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MASP1 VWF ZFPM2 EPAS1 SMAD9

1.09e-04180116527e8bbee388e64dd79d70b160b76d45b1f398006
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN ESCO2 UNC13A

1.11e-04951164756d76830b8e7e8903b2bc7a39a38880be684297
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRAG1 ZNF462 ZNF792 WNK3 NSMCE1

1.11e-041811165f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF NXPE2 MAST4 PTPRM EPAS1

1.14e-041821165840427d1c23d60482c943ff006b14007ed44d247
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SIM1 DSCAML1 BHMT PTPN3 ACSM2A

1.14e-0418211659d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA12 FAM178B UBE2C CCNA2 NXPH4

1.14e-041821165007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN ASIC3 ESCO2

1.16e-049611647a1a27d996c2bbcd922da524969f568f0575dfad
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

DOCK11 DSCAML1 ZNF462 MAST4 ACSM2A

1.20e-04184116551ed1ebfdef45149541917c66cbacad87072e51f
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

VWF MAST4 PTPRM EPAS1 SMAD9

1.20e-0418411650f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SIM1 RASGRP1 PTPN3 NXPH4

1.21e-04971164d93193cc8455373467a9e63d8b883c3139773a03
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SIM1 RASGRP1 PTPN3 NXPH4

1.21e-049711641dc648eb31b41419fbd859e9fab4a32ed4226a97
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KLHL32 ZNF785 EPHA2 PLS1 CDON

1.23e-041851165636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELPLG ZFP90 VWF DOCK11 ESCO2

1.23e-041851165969248b63d4ce335f223528de756bcddffadbd77
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast|bone_marrow / Manually curated celltypes from each tissue

MASP1 UBE2C OCRL ZFPM2 CCNA2

1.23e-041851165a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCellfacs-Lung-EPCAM-24m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN CCNA2 IHO1 UNC13A

1.27e-0418611659ce3bd121869215a4e6114a310f9d2fb5adaef61
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C NPHP4 CCNA2 ESCO2 EPHA2

1.27e-0418611653993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C NPHP4 CCNA2 ESCO2 EPHA2

1.27e-041861165ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCellfacs-Lung-EPCAM-24m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN CCNA2 IHO1 UNC13A

1.27e-04186116518c40203463d4dd8558c04977d52e400a8268f90
ToppCellfacs-Lung-EPCAM-24m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN CCNA2 IHO1 UNC13A

1.27e-041861165a7fd35eabcfb534019dfe5a8a600bf2ec47c1ac2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HDHD3 CDHR2 BHMT MAST4 PLS1

1.27e-041861165b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL32 DSCAML1 SPHKAP ELAPOR1 UNC13A

1.27e-041861165b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCelldroplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.30e-04187116599724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK|GI_small-bowel / Manually curated celltypes from each tissue

UBE2C CCNA2 ESCO2 CD300LB WNK3

1.30e-041871165265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

SIM1 DSCAML1 BHMT PTPN3 ACSM2A

1.30e-041871165d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.30e-041871165dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

VWF MAST4 PTPRM EPAS1 SMAD9

1.33e-041881165eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellfacs-Lung-24m-Hematologic-myeloid-leukocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UBE2C HEMGN CCNA2 IHO1 UNC13A

1.33e-04188116561b6047affa18c5e71210fcce449e2bbe7cf141b
ToppCellfacs-Lung-24m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UBE2C HEMGN CCNA2 IHO1 UNC13A

1.33e-041881165797ce39602f0f78081eb44a21da0d9443f7fd9cf
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Mega-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

VWF UBE2C HEMGN HECTD2 PRSS21

1.33e-0418811658e80e0714883e5c5e372d933682c5b55ebef7e62
ToppCelldroplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.40e-041901165a273fc119baebc11020009c923beafeebb6428c9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM1 BCL6 DSCAML1 PTPN3 MAST4

1.40e-04190116559bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.40e-0419011654288189e3a499c395896c950598810b02f401685
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PTPRM SLFN11 ACSM2A EPAS1

1.40e-041901165d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZNF174 UBE2C ZNF462 EPHA2 MMP14

1.40e-04190116539fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCelldroplet-Marrow-BM-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C HEMGN NXPE2 CCNA2 ESCO2

1.43e-04191116508be56a4055a73c920d345fd3b2052a5ccb675d8
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|356C / Donor, Lineage, Cell class and subclass (all cells)

UBE2C CCNA2 ESCO2 DNASE2B PRSS21

1.43e-041911165a2c235a55094e4fd5273d764c9e2967116b48c23
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

VWF ZFPM2 PTPRM ACSM2A EPAS1

1.47e-0419211655af3b2b38495e925497c48f605d618bbf970965d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDSS1 ZNF462 PTPRM SPHKAP ENTPD3

1.47e-041921165f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2C FKBP9 HEMGN CCNA2 ESCO2

1.47e-041921165a94f47a664a3c9d1b0250269674453309ab4bf95
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDSS1 ZNF462 PTPRM SPHKAP ENTPD3

1.47e-041921165690b3d17c481159bc96b8bc7f6a66b51343ee858
ComputationalGenes in the cancer module 95.

VWF RBMS1 UBE2C KLHL32 POF1B BHMT ZNF462 ELAPOR1 KCNMB3 NXPH4 TCTN1 PLXNA1 TBX5

3.43e-055606713MODULE_95
ComputationalGenes in the cancer module 163.

VWF RBMS1 UBE2C KLHL32 POF1B BHMT ZNF462 ELAPOR1 KCNMB3 NXPH4 TCTN1 PLXNA1 TBX5

3.76e-055656713MODULE_163
Diseaseplexin-A1 measurement

MMP14 PLXNA1

4.12e-0531102EFO_0801892
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

8.22e-0541102EFO_0020830
DiseaseFibroid Tumor

TSC2 SMAD3

2.05e-0461102C0023267
DiseaseSquamous cell carcinoma of lung

MAST4 EPHA2 WNK3

2.31e-04321103C0149782
DiseaseUterine Fibroids

TSC2 SMAD3

2.86e-0471102C0042133
Diseasemyocardial infarction (biomarker_via_orthology)

VWF CCNA2 TNFRSF1A MMP14 EPAS1

3.41e-041601105DOID:5844 (biomarker_via_orthology)
Diseasesynaptotagmin-11 measurement

GON4L ZFPM2

4.87e-0491102EFO_0802108
DiseasePulmonary arterial hypertension

EPAS1 SMAD9

6.08e-04101102C2973725
Diseasecerebellum cortex volume change measurement

PTPRM EPAS1

1.22e-03141102EFO_0021497
Diseaseintracranial aneurysm (is_marker_for)

VWF MMP14

1.22e-03141102DOID:10941 (is_marker_for)
Diseaseeye colour measurement

MYCBP2 SAXO1 SIM1 PTPN3 PTPRM

1.37e-032181105EFO_0009764
DiseaseP wave duration

EPAS1 TBX5

1.40e-03151102EFO_0005094
DiseaseChromosome Aberrations

UBE2C EPAS1

1.60e-03161102C0008625
DiseaseAutosome Abnormalities

UBE2C EPAS1

1.60e-03161102C0004403
DiseaseIdiopathic pulmonary arterial hypertension

EPAS1 SMAD9

1.60e-03161102C3203102
Diseasecyclic adenosine monophosphate measurement

MAST4 PTPRM

1.81e-03171102EFO_0010473
Diseaseischemia (implicated_via_orthology)

TNFRSF1A MMP14

1.81e-03171102DOID:326 (implicated_via_orthology)
Diseasesporadic amyotrophic lateral sclerosis

MASP1 KCNMB3 UNC13A PLXNA1

1.90e-031401104EFO_0001357
DiseaseBrugada syndrome

ZFPM2 TBX5

2.26e-03191102MONDO_0015263
Diseasecystathionine measurement

TEC TEC

2.26e-03191102EFO_0010474
Diseaselysophosphatidylcholine 20:5 measurement

AKR1D1 DNASE2B

2.26e-03191102EFO_0010364
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

CASP2 TSC2 EPAS1 WNK3

2.32e-031481104C0279702
Diseasebipolar disorder, schizophrenia, response to lithium ion

FAM178B MAIP1

2.50e-03201102GO_0010226, MONDO_0004985, MONDO_0005090
DiseasePR interval

MYCBP2 ABCA12 BCL6 ZFPM2 KCNMB3 EPAS1 TBX5

2.59e-034951107EFO_0004462
Diseasebody weight

RPS6KA5 EPB41L4B RBMS1 ZNF280C GON4L SIM1 BCL6 MAST4 SPHKAP HNRNPLL PLXNA1 EPAS1

2.62e-03126111012EFO_0004338
DiseaseLymphoma, Diffuse

BCL6 BHMT

2.76e-03211102C3714542
DiseaseLow Grade Lymphoma (neoplasm)

BCL6 BHMT

2.76e-03211102C0079747
DiseaseLymphoma, Intermediate-Grade

BCL6 BHMT

2.76e-03211102C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

BCL6 BHMT

2.76e-03211102C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

BCL6 BHMT

2.76e-03211102C0079757
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

VWF ZFPM2

2.76e-03211102EFO_0004286, EFO_0004792
DiseaseLymphoma, Undifferentiated

BCL6 BHMT

2.76e-03211102C0024306
DiseaseReticulosarcoma

BCL6 BHMT

2.76e-03211102C0024302
DiseaseLymphoma, Mixed-Cell

BCL6 BHMT

2.76e-03211102C0024304
Diseasebehavioural disinhibition measurement

MASP1 ZFPM2 DNAH9

2.80e-03751103EFO_0006946
DiseaseLymphoma, Non-Hodgkin, Familial

BCL6 BHMT

3.03e-03221102C4721532
DiseaseLymphoma, Small Noncleaved-Cell

BCL6 BHMT

3.03e-03221102C0079770
Diseasevenous thromboembolism, tissue plasminogen activator measurement

VWF ZFPM2

3.31e-03231102EFO_0004286, EFO_0004791

Protein segments in the cluster

PeptideGeneStartEntry
EDKNSYTPCLNQFPQ

UNC13A

1061

Q9UPW8
SQPLAYHTPDCNKQG

BHMT

246

Q93088
TGQVKVYNNCPPHNS

EPAS1

196

Q99814
PIHTNPCFYQSSEKS

APLF

56

Q8IW19
HKSLCVNEVPSFYVP

ANKRD11

2636

Q6UB99
VTPCQTPYTQYHLNK

CAPS2

101

Q9BXY5
SNQVECHPYFTQPKL

AKR1D1

191

P51857
ENVQECPKFNYSPPH

ABCA12

1851

Q86UK0
YKFPHLQNCVTVGES

ACSM2A

326

Q08AH3
PHNFQETTYLKPTFC

RASGRP1

541

O95267
APTDYCFVLKHPQIQ

APBB1IP

376

Q7Z5R6
PYNQPKRNTIQFTHT

AQR

791

O60306
LQNSPTKNHLTNPCY

ENTPD3

276

O75355
HNEITFCIQNYTPKV

MMP14

121

P50281
VQKVCPDYNFQSEHP

NXPH4

291

O95158
PHTTDQDLVKLCQPY

RBMS1

71

P29558
PIAEQLYKDFSHPCT

HDHD3

96

Q9BSH5
KNIIQPPSCVLHYYN

HNRNPLL

446

Q8WVV9
VNKYIATQGPLPHTC

PTPN3

711

P26045
NCPEFVPRQHYQKET

LARP1

501

Q6PKG0
NQIQHYFCDAPPILK

OR10G7

171

Q8NGN6
NQIQHYFCDAPPILK

OR10G4

171

Q8NGN3
CPQRSYSTEEKPQQH

MAIP1

91

Q8WWC4
KPYCHAHNPKNNTFT

NRAP

51

Q86VF7
IQTCKFNSKYQSPQP

IHO1

466

Q8IYA8
PVIKPEVDSTFCHNY

LRRC17

231

Q8N6Y2
CPTNTILKAHQPYGV

ELAPOR1

621

Q6UXG2
VENYLAHKQNFCPVT

ZFPM2

866

Q8WW38
AHTCFNQLCLPPYKS

HECTD2

741

Q5U5R9
NLAPHFLALCKPNYT

PLPPR5

146

Q32ZL2
LFNTYPCLHKPNNND

PLS1

371

Q14651
IDNPQNIQAHLYKCP

PLXNA1

796

Q9UIW2
FPCNYTPKEQVFSSH

PIERCE2

76

H3BRN8
KYQTPPHQNFADLEQ

KDM4E

106

B2RXH2
SEAAQSCQPKPIHYD

MYCLP1

256

P12525
HSDEKPYQCPVCQQR

MAZ

301

P56270
NQPLKTPCFTLHYAA

RPS6KA5

576

O75582
VCSPQQYKNCAHPAI

ASIC3

341

Q9UHC3
QQKLISHCYIPQSPE

PTPDC1

426

A2A3K4
LQDPIAPTNSTCQHY

MSL2

51

Q9HCI7
HCYHQSSQAQQPPEK

POF1B

31

Q8WVV4
QESAEPKYLPHKTCN

HEMGN

316

Q9BXL5
VSHINSNYKLCPSYP

MTMR4

176

Q9NYA4
ENCSLQYTLKPHPAL

NPHP4

181

O75161
DQVQIHTYFKPPSCP

FKBP9

146

O95302
CKVEIHGLSPQPQTY

CCNYL3

301

P0C7X3
VNDHKPEFYNCSLPA

CDHR2

346

Q9BYE9
PSNCSLPYHVYNIKA

DNASE2B

276

Q8WZ79
QGNITHCAEPYIKNS

DOCK11

486

Q5JSL3
PYINLVKHLTSACPN

PDSS1

56

Q5T2R2
AVPIPHRANKSDYCN

DSCAML1

1886

Q8TD84
PHTYEDPNQAVLKFT

EPHA2

591

P29317
CAAYNPVTHQLKVEP

CDON

191

Q4KMG0
HQYNPKFQTLFQPCN

GON4L

741

Q3T8J9
HKQPEYFCVSPDTQE

CCDC66

386

A2RUB6
ETQIYPNHSSPCLEQ

G6PC2

86

Q9NQR9
PNVCHSNIYSPKETI

BCL6

251

P41182
LFPSPNKKHCFYQNS

ESCO2

26

Q56NI9
IPIVDHSTCQKAYAP

MASP1

606

P48740
SCSSQEKLHQLPYQP

MAST4

306

O15021
GKYPCLQVFVNLSHP

KCNMB3

121

Q9NPA1
PVEQTQSPNLYCHFA

DNAH9

2746

Q9NYC9
TQYFLHQQPANCKVE

CCNA2

316

P20248
FQHPKTQQVSLCYRL

FDXACB1

576

Q9BRP7
EPKHCFTSPDYQQQC

SDE2

146

Q6IQ49
SCINDVPPQYFQHLD

SEC24C

451

P53992
NTPKVNPCFASSNIY

CFAP47

1731

Q6ZTR5
LCSKTNPEVHNYQPQ

EPB41L4B

436

Q9H329
VKPCTPEFYQTHFQL

CASP2

176

P42575
VAKYFQSNAEPRCPH

NSMCE1

216

Q8WV22
KCYPVPIHFQNASLL

PTPRM

641

P28827
NYPVGAPDHISVKQC

SELPLG

306

Q14242
PAQSTLQTKHPDIYC

SPHKAP

911

Q2M3C7
TVQAHYTCPKGAPAQ

SAXO1

306

Q8IYX7
YPLPQEHSQIYHCTK

TBX5

311

Q99593
VIPCQNKYPFQVVHD

TEC

71

P42680
CTNNAHPPDYVIQNQ

NXPE2

536

Q96DL1
ELLTHCQPQAQYFSP

FAM178B

661

Q8IXR5
PLPESYDQFKQNIHS

PNLDC1

271

Q8NA58
KHSLCFANYQQPPPT

SIM1

601

P81133
QAIYKLPCVHFCQPQ

SLFN11

276

Q7Z7L1
QQPPYSKCFEDHLEQ

SPATA31D4

481

Q6ZUB0
SILCYHPAKPFQSQL

MYCBP2

3361

O75592
NEINHFYCADPPLIK

OR5M8

171

Q8NGP6
PNKVNHFFCDYSPLL

OR5P3

171

Q8WZ94
PCHFSFIPKLNDSQY

OCRL

596

Q01968
PFGSKQKEVCINPYH

SMAD9

116

O15198
APEQGSLTVQCHYKQ

CD300LB

26

A8K4G0
NHCVPPYSESKYQLQ

DNTTIP2

616

Q5QJE6
QQPPYSKCFEDHLEQ

SPATA31D3

481

P0C874
SPNAQKPFAHYQRHC

ZNF174

266

Q15697
HKVLAPATFYAICQQ

VWF

2151

P04275
QHTYPKSLNCVAFHP

TEP1

1796

Q99973
HNNLDLQPVTYCEPA

SMAD3

216

P84022
INPSIFCIHITNYKP

TCTN1

146

Q2MV58
YNFHQPKSGEVTPSC

TPP2

826

P29144
YCSPSVPVHFNIQQD

PRAG1

1036

Q86YV5
VVCTSKPPIYLQHQG

ZUP1

476

Q96AP4
QTTHPRQKPFVCEAY

ZNF792

151

Q3KQV3
HIAANPKPTNKFFQC

ZNF462

96

Q96JM2
PVTYTKHIQPICLQA

PRSS21

146

Q9Y6M0
QYPTPFQLQCHIEST

ZNF280C

361

Q8ND82
YFETQHQSVPQCLSK

VEZT

401

Q9HBM0
PLFVQHKCTQHRPYT

UNK

46

Q9C0B0
EQQFHPEIYKSTKCN

UNK

286

Q9C0B0
QKHFPTDPSKCVEYN

PRPF18

326

Q99633
DSVCPQGKYIHPQNN

TNFRSF1A

41

P19438
NLAQPKEVSCHYVPN

THEGL

226

P0DJG4
YQHIHQKSFSCPEPA

ZNF692

351

Q9BU19
LQHQFIHTGEKPYPC

ZNF785

216

A8K8V0
TNPSKFNQYIVCLAH

TSC2

876

P49815
VKFLTPCYHPNVDTQ

UBE2C

96

O00762
QQAISHPGEKPYQCN

ZFP90

486

Q8TF47
NYPFGTCQQRKLFPH

PIFO

11

Q8TCI5
KQASIFIPVYPCHQT

WNK3

996

Q9BYP7
YFTCPNLQTLQVPHH

KLHL32

601

Q96NJ5
QYSPHCKLLIVTNPV

LDHAL6A

126

Q6ZMR3
NATTPHYVRCIKPND

MYO5A

651

Q9Y4I1
PDTPAFIQHKVNAYN

NEB

541

P20929