Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAAF5 DNAH5 DNAH6 DNAH8 DNAH11

2.11e-0737725GO:0045505
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH5 DNAH6 DNAH8 DNAH11

4.58e-0718724GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH5 DNAH6 DNAH8 DNAH11

2.98e-0628724GO:0051959
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1A DNAH5 DNAH6 DNAH8 DNAH11

6.75e-05118725GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH5 DNAH6 DNAH8 DNAH11

1.19e-0470724GO:0003777
GeneOntologyMolecularFunctionNAD+ nucleosidase activity

IL1RAPL1 IL18RAP

8.27e-0412722GO:0003953
GeneOntologyBiologicalProcesscilium movement

DNAAF5 RSPH4A INPP5B CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

2.39e-082617210GO:0003341
GeneOntologyBiologicalProcesscilium movement involved in cell motility

RSPH4A INPP5B CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

4.84e-08210729GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

RSPH4A INPP5B CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

5.92e-08215729GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

RSPH4A INPP5B CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

5.92e-08215729GO:0001539
GeneOntologyBiologicalProcessmicrotubule-based process

CYLD DNAAF5 MAPK15 RSPH4A INPP5B CFAP221 VPS13A MACF1 SLAIN1 DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11 WDR72

2.99e-0610587215GO:0007017
GeneOntologyBiologicalProcessmicrotubule-based movement

DNAAF5 RSPH4A INPP5B CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

7.90e-064937210GO:0007018
GeneOntologyBiologicalProcesscilium assembly

TBC1D8 CYLD DNAAF5 MAPK15 RSPH4A TRIM32 CFAP221 DNAH5 DNAH8

2.35e-05444729GO:0060271
GeneOntologyBiologicalProcesscilium organization

TBC1D8 CYLD DNAAF5 MAPK15 RSPH4A TRIM32 CFAP221 DNAH5 DNAH8

4.04e-05476729GO:0044782
GeneOntologyBiologicalProcessflagellated sperm motility

INPP5B CFAP221 VPS13A DNAH5 ATP2B4 DNAH11

4.73e-05186726GO:0030317
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

RSPH4A CFAP221 DNAH5 DNAH11

5.37e-0559724GO:0003351
GeneOntologyBiologicalProcesssperm motility

INPP5B CFAP221 VPS13A DNAH5 ATP2B4 DNAH11

5.81e-05193726GO:0097722
GeneOntologyBiologicalProcessextracellular transport

RSPH4A CFAP221 DNAH5 DNAH11

6.53e-0562724GO:0006858
GeneOntologyBiologicalProcessclathrin coat assembly

AP1B1 AP2B1 SYT11

6.87e-0523723GO:0048268
GeneOntologyBiologicalProcessouter dynein arm assembly

DNAAF5 DNAH5 DNAH8

7.83e-0524723GO:0036158
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

TBC1D8 CYLD DNAAF5 MAPK15 MYO1A RSPH4A TRIM32 CFAP221 DNAH5 DNAH8

1.07e-046707210GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

TBC1D8 CYLD DNAAF5 MAPK15 MYO1A RSPH4A TRIM32 CFAP221 DNAH5 DNAH8

1.28e-046857210GO:0030031
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAAF5 DNAH5 DNAH8

3.95e-0441723GO:0070286
GeneOntologyBiologicalProcessregulation of microtubule-based process

CYLD MAPK15 RSPH4A MACF1 SLAIN1 DNAH11

5.56e-04293726GO:0032886
GeneOntologyBiologicalProcessregulation of cilium assembly

TBC1D8 CYLD MAPK15 TRIM32

5.56e-04108724GO:1902017
GeneOntologyBiologicalProcessaxoneme assembly

DNAAF5 RSPH4A DNAH5 DNAH8

5.76e-04109724GO:0035082
GeneOntologyCellularComponentmotile cilium

DNAAF5 SPAG4 RSPH4A CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

3.70e-073557210GO:0031514
GeneOntologyCellularComponent9+2 motile cilium

RSPH4A CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

1.60e-06238728GO:0097729
GeneOntologyCellularComponentaxoneme

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH8 DNAH11

7.21e-06207727GO:0005930
GeneOntologyCellularComponentciliary plasm

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH8 DNAH11

7.44e-06208727GO:0097014
GeneOntologyCellularComponentcytoplasmic region

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH8 UNC13A DNAH11

3.28e-05360728GO:0099568
GeneOntologyCellularComponentdynein complex

DNAH5 DNAH6 DNAH8 DNAH11

3.59e-0554724GO:0030286
GeneOntologyCellularComponentsupramolecular fiber

CYLD SPAG4 COL11A2 MYO1A TRIM32 JPH2 MACF1 SLAIN1 DAXX DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

4.21e-0511797214GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CYLD SPAG4 COL11A2 MYO1A TRIM32 JPH2 MACF1 SLAIN1 DAXX DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

4.53e-0511877214GO:0099081
GeneOntologyCellularComponentcilium

CYLD DNAAF5 SPAG4 MAPK15 RSPH4A CFAP221 VPS13A DNAH5 DNAH6 DNAH8 ATP2B4 DNAH11

5.23e-058987212GO:0005929
GeneOntologyCellularComponentaxonemal dynein complex

DNAH5 DNAH6 DNAH8

8.53e-0525723GO:0005858
GeneOntologyCellularComponentmicrotubule

CYLD SPAG4 MACF1 SLAIN1 DAXX DNAH5 DNAH6 DNAH8 DNAH11

8.69e-05533729GO:0005874
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH8 DNAH11

1.09e-04317727GO:0032838
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

1.74e-046722GO:0097728
GeneOntologyCellularComponentouter dynein arm

DNAH5 DNAH8

7.55e-0412722GO:0036157
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

CUL5 DCAF1 CAND1 FBXO31 FBXO27

8.25e-04212725GO:0031461
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

CYLD SPAG4 MYO1A MACF1 SLAIN1 DAXX DNAH5 DNAH6 DNAH8 DNAH11

9.83e-048997210GO:0099513
GeneOntologyCellularComponentubiquitin ligase complex

CUL5 DCAF1 CAND1 FBXO31 CBX4 FBXO27

1.34e-03352726GO:0000151
GeneOntologyCellularComponentSCF ubiquitin ligase complex

CUL5 FBXO31 FBXO27

1.82e-0370723GO:0019005
GeneOntologyCellularComponentmicrotubule associated complex

DNAH5 DNAH6 DNAH8 DNAH11

2.32e-03161724GO:0005875
HumanPhenoAbnormal breath sound

DNAAF5 RSPH4A CFAP221 GNPTAB LAMB3 DNAH5 DNAH11

3.07e-06133267HP:0030829
HumanPhenoPeribronchovascular interstitial thickening

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

3.78e-0649265HP:0025177
HumanPhenoEctopic pregnancy

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

3.78e-0649265HP:0031456
HumanPhenoPulmonary situs ambiguus

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

3.78e-0649265HP:0011617
HumanPhenoAbnormal pulmonary situs morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

3.78e-0649265HP:0011615
HumanPhenoLithoptysis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

3.78e-0649265HP:0032543
HumanPhenoAtrial situs ambiguous

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

4.18e-0650265HP:0011539
HumanPhenoAbnormal inferior vena cava morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.61e-0653265HP:0025576
HumanPhenoAbnormal atrial arrangement

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.16e-0654265HP:0011535
HumanPhenoNasal congestion

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.04e-0560265HP:0001742
HumanPhenoAbnormal pulmonary interstitial morphology

DNAAF5 RSPH4A CFAP221 NAF1 DNAH5 BMP15 DNAH11

1.10e-05161267HP:0006530
HumanPhenoDecreased nasal nitric oxide

DNAAF5 RSPH4A DNAH5 DNAH11

1.16e-0529264HP:0033036
HumanPhenoRecurrent mycobacterial infections

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.23e-0562265HP:0011274
HumanPhenoWheezing

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.43e-0564265HP:0030828
HumanPhenoPolysplenia

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.67e-0566265HP:0001748
HumanPhenoRhinitis

DNAAF5 RSPH4A TRIM32 CFAP221 DNAH5 DNAH11

1.67e-05113266HP:0012384
HumanPhenoCiliary dyskinesia

DNAAF5 RSPH4A DNAH5 DNAH11

1.74e-0532264HP:0012265
HumanPhenoAbnormal sperm motility

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH8 DNAH11

1.85e-05115266HP:0012206
HumanPhenoAbnormal sperm physiology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH8 DNAH11

1.85e-05115266HP:0034809
HumanPhenoRecurrent upper and lower respiratory tract infections

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.93e-0568265HP:0002873
HumanPhenoRecurrent sinopulmonary infections

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.93e-0568265HP:0005425
HumanPhenoProductive cough

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.93e-0568265HP:0031245
HumanPhenoChronic sinusitis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

2.08e-0569265HP:0011109
HumanPhenoAbnormal ciliary motility

DNAAF5 RSPH4A DNAH5 DNAH11

2.23e-0534264HP:0012262
HumanPhenoChronic rhinitis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

2.74e-0573265HP:0002257
HumanPhenoAbnormal respiratory motile cilium physiology

DNAAF5 RSPH4A DNAH5 DNAH11

2.81e-0536264HP:0012261
HumanPhenoNasal polyposis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

2.93e-0574265HP:0100582
HumanPhenoAtelectasis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

4.28e-0580265HP:0100750
HumanPhenoAbnormal nasal mucosa morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

4.28e-0580265HP:0000433
HumanPhenoPersistent left superior vena cava

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.11e-0583265HP:0005301
HumanPhenoAnomalous pulmonary venous return

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.11e-0583265HP:0010772
HumanPhenoFemale infertility

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.42e-0584265HP:0008222
HumanPhenoAbnormal superior vena cava morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.74e-0585265HP:0025575
HumanPhenoTransposition of the great arteries

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.74e-0585265HP:0001669
HumanPhenoAbnormal vena cava morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.78e-0588265HP:0030971
HumanPhenoAbnormal pulmonary vein morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

7.16e-0589265HP:0030968
HumanPhenoAbnormality of the pulmonary veins

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

7.16e-0589265HP:0011718
HumanPhenoAbnormal vena cava morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

7.16e-0589265HP:0005345
HumanPhenoAsplenia

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

7.97e-0591265HP:0001746
HumanPhenoDouble outlet right ventricle

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

9.31e-0594265HP:0001719
HumanPhenoCongenital malformation of the right heart

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.03e-0496265HP:0011723
HumanPhenoAplasia/Hypoplasia of the spleen

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.14e-0498265HP:0010451
HumanPhenoSupernumerary spleens

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.31e-04101265HP:0009799
HumanPhenoDecreased fertility in females

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.51e-04104265HP:0000868
HumanPhenoRespiratory failure

DNAAF5 RSPH4A CFAP221 LAMB3 DNAH5 UNC13A DNAH11

2.49e-04262267HP:0002878
HumanPhenoAbnormal respiratory epithelium morphology

DNAAF5 RSPH4A DNAH11

3.55e-0428263HP:0012253
HumanPhenoAbnormal respiratory motile cilium morphology

DNAAF5 RSPH4A DNAH11

3.55e-0428263HP:0005938
HumanPhenoDecreased fertility

DNAAF5 RSPH4A TRIM32 CFAP221 DNAH5 DNAH8 BMP15 DNAH11

4.20e-04380268HP:0000144
HumanPhenoAbnormal fingertip morphology

DNAAF5 RSPH4A CFAP221 LAMB3 DNAH5 DNAH11

4.39e-04203266HP:0001211
HumanPhenoRecurrent lower respiratory tract infections

DNAAF5 COL11A2 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

4.45e-04288267HP:0002783
HumanPhenoMale infertility

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH8 DNAH11

5.13e-04209266HP:0003251
HumanPhenoAbnormal sputum

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.28e-04136265HP:0032016
HumanPhenoAirway obstruction

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

5.46e-04137265HP:0006536
HumanPhenoAbnormal bronchus morphology

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

5.97e-04215266HP:0025426
HumanPhenoAbdominal situs inversus

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.43e-04142265HP:0003363
HumanPhenoSitus inversus totalis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.43e-04142265HP:0001696
HumanPhenoAbnormal spatial orientation of the cardiac segments

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.43e-04142265HP:0011534
HumanPhenoAbnormality of abdominal situs

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

6.43e-04142265HP:0011620
HumanPhenoHeterotaxy

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

7.08e-04145265HP:0030853
HumanPhenoInfertility

DNAAF5 RSPH4A TRIM32 CFAP221 DNAH5 DNAH8 DNAH11

7.50e-04314267HP:0000789
HumanPhenoRecurrent bacterial infections

DNAAF5 RSPH4A CFAP221 LAMB3 DNAH5 DNAH11

7.60e-04225266HP:0002718
HumanPhenoRecurrent otitis media

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

7.96e-04227266HP:0000403
HumanPhenoClubbing

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

8.77e-04152265HP:0001217
HumanPhenoNeonatal respiratory distress

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

9.31e-04154265HP:0002643
HumanPhenoDecreased fertility in males

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH8 DNAH11

9.77e-04236266HP:0012041
HumanPhenoChronic otitis media

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

9.87e-04156265HP:0000389
HumanPhenoRecurrent upper respiratory tract infections

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

9.99e-04237266HP:0002788
HumanPhenoAbnormal pulmonary thoracic imaging finding

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.02e-03157265HP:0031983
HumanPhenoIntestinal malrotation

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.02e-03157265HP:0002566
HumanPhenoDextrocardia

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.08e-03159265HP:0001651
HumanPhenoAbnormal anatomic location of the heart

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.11e-03160265HP:0004307
HumanPhenoCough

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.11e-03160265HP:0012735
HumanPhenoAbnormality of the bronchi

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

1.21e-03246266HP:0002109
HumanPhenoAbnormal nasopharynx morphology

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

1.29e-03249266HP:0001739
HumanPhenoSinusitis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.45e-03170265HP:0000246
HumanPhenoAbnormal pharynx morphology

DNAAF5 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

1.62e-03260266HP:0033151
HumanPhenoBronchiectasis

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.65e-03175265HP:0002110
HumanPhenoOtitis media

DNAAF5 RSPH4A TRIM32 CFAP221 GNPTAB DNAH5 DNAH11

1.77e-03363267HP:0000388
HumanPhenoImmotile cilia

DNAAF5 RSPH4A

1.89e-0313262HP:0012263
HumanPhenoPregnancy history

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

1.97e-03182265HP:0002686
HumanPhenoPast medical history

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

2.01e-03183265HP:0032443
HumanPhenoConductive hearing impairment

DNAAF5 COL11A2 RSPH4A CFAP221 GNPTAB DNAH5 DNAH11

2.07e-03373267HP:0000405
HumanPhenoAbnormal paranasal sinus morphology

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

2.32e-03189265HP:0000245
MousePhenoimmotile respiratory cilia

DNAAF5 AP1B1 DNAH5 DNAH11

4.91e-0717554MP:0011649
MousePhenoabnormal respiratory motile cilium physiology

DNAAF5 AP1B1 DNAH5 DNAH11

4.73e-0629554MP:0011055
MousePhenobiventricular, ambiguous atrioventricular connection

DNAH5 DNAH11

1.52e-052552MP:0011511
MousePhenobiventricular, discordant atrioventricular connection

DNAH5 DNAH11

4.55e-053552MP:0011510
MousePhenoabnormal motile cilium physiology

DNAAF5 AP1B1 DNAH5 DNAH11

4.67e-0551554MP:0013209
MousePhenoabnormal respiratory epithelium physiology

DNAAF5 AP1B1 DNAH5 DNAH11

4.67e-0551554MP:0014200
MousePhenoabnormal cilium physiology

DNAAF5 AP1B1 DNAH5 DNAH11

5.44e-0553554MP:0013208
MousePhenositus inversus

DNAAF5 AP1B1 DNAH5 DNAH11

8.88e-0560554MP:0002766
MousePhenositus inversus totalis

AP1B1 DNAH5 DNAH11

9.65e-0523553MP:0011252
MousePhenoleft pulmonary isomerism

AP1B1 DNAH5 DNAH11

2.40e-0431553MP:0003178
MousePhenosuperior-inferior ventricles

DNAH5 DNAH11

3.15e-047552MP:0011254
MousePhenositus inversus with levocardia

DNAH5 DNAH11

3.15e-047552MP:0011253
MousePhenoleft-sided isomerism

AP1B1 DNAH5 DNAH11

3.16e-0434553MP:0000542
MousePhenoleft atrial isomerism

DNAH5 DNAH11

4.19e-048552MP:0008461
MousePhenoheterotaxia

DNAAF5 AP1B1 DNAH5 DNAH11

4.26e-0490554MP:0004133
MousePhenoabdominal situs inversus

DNAH5 DNAH11

5.38e-049552MP:0011249
MousePhenoheart right ventricle hypertrophy

AP2B1 DNAH5 DNAH11

5.94e-0442553MP:0000276
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704IPR013602
DomainDHC_N2

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704PF08393
DomainMT

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704PF12777
DomainAAA_8

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704PF12780
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704IPR011704
DomainAAA_5

DNAH5 DNAH6 DNAH8 DNAH11

1.76e-0714704PF07728
DomainDHC_fam

DNAH5 DNAH6 DNAH8 DNAH11

2.39e-0715704IPR026983
DomainDynein_heavy_dom

DNAH5 DNAH6 DNAH8 DNAH11

2.39e-0715704IPR004273
DomainDynein_heavy

DNAH5 DNAH6 DNAH8 DNAH11

2.39e-0715704PF03028
DomainDHC_N1

DNAH5 DNAH8 DNAH11

2.79e-068703PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH8 DNAH11

2.79e-068703IPR013594
Domain-

AP1B1 AP2B1

1.38e-0527022.60.40.1150
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

1.38e-052702IPR013037
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

4.14e-053702IPR016342
DomainB2-adapt-app_C

AP1B1 AP2B1

4.14e-053702PF09066
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

8.27e-054702IPR015151
DomainB2-adapt-app_C

AP1B1 AP2B1

8.27e-054702SM01020
DomainAP_beta

AP1B1 AP2B1

1.37e-045702IPR026739
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

2.06e-046702IPR012295
Domain-

AP1B1 AP2B1

2.06e-0467023.30.310.10
DomainCoatomer/calthrin_app_sub_C

AP1B1 AP2B1

3.82e-048702IPR009028
DomainClathrin_a/b/g-adaptin_app_Ig

AP1B1 AP2B1

4.90e-049702IPR008152
DomainAlpha_adaptinC2

AP1B1 AP2B1

4.90e-049702PF02883
DomainAlpha_adaptinC2

AP1B1 AP2B1

4.90e-049702SM00809
DomainARM-like

DCAF1 DNAAF5 CAND1 AP1B1 AP2B1 DAXX

5.22e-04270706IPR011989
DomainIL-1_rcpt_fam

IL1RAPL1 IL18RAP

7.45e-0411702IPR015621
DomainGrpE_coiled_coil

TRIM32 DNAH8

8.92e-0412702IPR013805
DomainCoatomer/clathrin_app_Ig-like

AP1B1 AP2B1

8.92e-0412702IPR013041
DomainHEAT

DNAAF5 CAND1 EIF4G3

1.34e-0358703IPR000357
DomainClathrin/coatomer_adapt-like_N

AP1B1 AP2B1

1.41e-0315702IPR002553
DomainAdaptin_N

AP1B1 AP2B1

1.41e-0315702PF01602
Domain-

DCAF1 DNAAF5 CAND1 AP1B1 AP2B1

1.47e-032227051.25.10.10
DomainARM-type_fold

DCAF1 DNAAF5 CAND1 AP1B1 AP2B1 EIF4G3

1.69e-03339706IPR016024
DomainAAA+_ATPase

DNAH5 DNAH6 DNAH8 DNAH11

2.10e-03144704IPR003593
DomainAAA

DNAH5 DNAH6 DNAH8 DNAH11

2.10e-03144704SM00382
DomainHEAT_REPEAT

DNAAF5 CAND1 EIF4G3

2.31e-0370703PS50077
DomainTIR

IL1RAPL1 IL18RAP

2.78e-0321702SM00255
DomainTIR

IL1RAPL1 IL18RAP

3.05e-0322702PF01582
Domain-

IL1RAPL1 IL18RAP

3.33e-03237023.40.50.10140
DomainTIR

IL1RAPL1 IL18RAP

3.62e-0324702PS50104
DomainTIR_dom

IL1RAPL1 IL18RAP

3.93e-0325702IPR000157
DomainFYVE

RBSN PLEKHF1

5.27e-0329702PF01363
DomainFYVE

RBSN PLEKHF1

5.27e-0329702SM00064
DomainSpectrin_repeat

MCF2 MACF1

5.27e-0329702IPR002017
DomainGalactose-bd-like

SPAG4 LAMB3 FBXO27

5.30e-0394703IPR008979
DomainSpectrin/alpha-actinin

MCF2 MACF1

6.39e-0332702IPR018159
DomainSPEC

MCF2 MACF1

6.39e-0332702SM00150
DomainZnf_FYVE-rel

RBSN PLEKHF1

7.19e-0334702IPR017455
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH5 DNAH6 DNAH8 DNAH11

2.51e-0627514M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH5 DNAH6 DNAH8 DNAH11

1.69e-0543514M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH5 DNAH6 DNAH8 DNAH11

2.03e-0545514M47670
Pubmed

Primary Ciliary Dyskinesia

DNAAF5 RSPH4A DNAH5 DNAH8 DNAH11

6.36e-093272520301301
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH5 DNAH6 DNAH8 DNAH11

1.66e-08147249373155
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

RSPH4A DNAH5 DNAH11

1.69e-07672333347437
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH8 DNAH11

2.96e-07772331178125
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH5 DNAH8 DNAH11

2.96e-0777239256245
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

4.23e-06272232357925
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

4.23e-06272219410201
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAH5 DNAH6

1.27e-05372226918822
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

TBC1D8 AP1B1 TSPOAP1 VPS13A ZMIZ1 EIF4G3 ATP2B4 DNAH11

1.88e-0555272810737800
Pubmed

A targeted next-generation sequencing panel reveals novel mutations in Japanese patients with primary ciliary dyskinesia.

RSPH4A DNAH5

2.53e-05472228939216
Pubmed

Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.

AP1B1 AP2B1

2.53e-05472217290217
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

2.53e-05472218492703
Pubmed

Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1.

CYLD SMG7

2.53e-05472232602581
Pubmed

ATM binds to beta-adaptin in cytoplasmic vesicles.

AP1B1 AP2B1

2.53e-0547229707615
Pubmed

Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.

AP1B1 AP2B1

2.53e-0547227534311
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TBC1D8 CYLD SMG7 MACF1 DAXX CBX4 HSF2 STAT2

2.95e-0558872838580884
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

CUL5 DCAF1 CYLD COL11A2 CAND1 MYO1A AP2B1 MTHFD1L NAF1 EIF4G3

4.11e-051005721019615732
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

4.21e-05572222499950
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH11

4.21e-05572226909801
Pubmed

Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.

AP1B1 AP2B1

4.21e-05572216723738
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

AP1B1 AP2B1 DNAH5 DNAH11

5.70e-0510072425807483
Pubmed

Differential dynamics of cullin deneddylation via COP9 signalosome subunit 5 interaction.

CUL5 CAND1

6.31e-05672236423380
Pubmed

Clathrin.

AP1B1 AP2B1

6.31e-05672210966473
Pubmed

HIV: Ringside views.

CUL5 DCAF1

6.31e-05672224402277
Pubmed

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.

AP1B1 AP2B1

1.17e-0487229811611
Pubmed

SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies.

DAXX CBX4

1.17e-04872227211601
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TBC1D8 RBSN AP1B1 ST3GAL5 MACF1 FAM114A2 ATP2B4 WDR72

1.20e-0471972835337019
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH5 DNAH6 DNAH8

1.29e-04477238812413
Pubmed

Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.

AP1B1 AP2B1

1.51e-04972212429846
Pubmed

CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.

DCAF1 DAXX BMP15

1.85e-045372324357321
Pubmed

Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.

AP1B1 AP2B1

1.88e-041072212383505
Pubmed

NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.

CUL5 CAND1

1.88e-041072212504025
Pubmed

Regulation of cullin RING E3 ubiquitin ligases by CAND1 in vivo.

CUL5 CAND1

1.88e-041072221249194
Pubmed

HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.

CUL5 CAND1

1.88e-041072221149631
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

TSPOAP1 UNC13A

2.30e-041172234767769
Pubmed

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia.

IL1RAPL1 MCF2

2.30e-041172220479760
Pubmed

An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.

CUL5 DCAF1 CAND1

2.54e-045972319295130
Pubmed

Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).

CUL5 FBXO31

2.75e-041272225505247
Pubmed

SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.

CUL5 CAND1

2.75e-041272218826954
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

DCAF1 DNAAF5 TRIM32 EXD2 ATP2B4

3.04e-0428272535007762
Pubmed

Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.

DNAH5 DNAH6

3.25e-041372235942101
Pubmed

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

DNAH5 DNAH11

3.25e-041372217884984
Pubmed

Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins.

AP1B1 AP2B1

3.25e-04137229882340
Pubmed

A protein interaction landscape of breast cancer.

DCAF1 DNAAF5 CAND1 AP2B1 LAMB3 MACF1 ATP2B4

3.42e-0463472734591612
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

CUL5 DNAAF5 CAND1 AP1B1 AP2B1 MTHFD1L

3.49e-0445172636168627
Pubmed

140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.

AP1B1 AP2B1 MTHFD1L ATP2B4

3.73e-0416372416512683
Pubmed

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

DNAAF5 SMG7 TRIM32 NAF1 VPS13A CRAMP1

3.74e-0445772632968282
Pubmed

Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.

DCAF1 CAND1

3.78e-041472218606781
Pubmed

Herpes virus deneddylases interrupt the cullin-RING ligase neddylation cycle by inhibiting the binding of CAND1.

CUL5 CAND1

3.78e-041472222474075
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

AP1B1 AP2B1 TRIM32 EXD2 NAF1 EIF4G3

3.96e-0446272631138677
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

CUL5 CYLD AP2B1 TRIM32 FBXO31 MACF1

4.90e-0448172628190767
Pubmed

HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.

AP1B1 AP2B1

4.98e-041672221762802
Pubmed

Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.

CBX4 ZHX1

4.98e-041672227068747
Pubmed

Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.

NAF1 DAXX

4.98e-041672225416818
Pubmed

HIV-1 accessory proteins--ensuring viral survival in a hostile environment.

CUL5 DCAF1

5.63e-041772218541215
Pubmed

The frantic play of the concealed HIV envelope cytoplasmic tail.

AP1B1 AP2B1

6.33e-041872223705972
Pubmed

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.

CUL5 CAND1

6.33e-041872226906416
Pubmed

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.

AP1B1 AP2B1

6.33e-041872223211419
Pubmed

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.

DCAF1 DAXX

7.06e-041972227626385
Pubmed

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

CUL5 CAND1

7.06e-041972222405651
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CUL5 CAND1 AP1B1 AP2B1 MACF1 EIF4G3 DNAH6 ATP2B4 UNC13A DNAH11

7.09e-041431721037142655
Pubmed

The Nef-infectivity enigma: mechanisms of enhanced lentiviral infection.

AP1B1 AP2B1

7.84e-042072222103831
Pubmed

COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.

CUL5 CAND1

7.84e-042072221778237
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

KLHL11 CAND1 DNAH5

7.96e-048772337495603
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CYLD CAND1 AP1B1 AP2B1 MACF1 TMEM132B ATP2B4 UNC13A

8.40e-0496372828671696
Pubmed

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

CUL5 DCAF1

8.65e-042172222190037
Pubmed

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development.

CAND1 AP1B1 MTHFD1L

8.78e-049072328978906
Pubmed

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

CUL5 CAND1

9.50e-042272230587576
Pubmed

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.

DCAF1 AP2B1

9.50e-042272226950368
Pubmed

Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.

CYLD IL18RAP

9.50e-042272225642632
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CAND1 TRIM32 MTHFD1L EXD2 PHRF1 MACF1 DAXX CBX4 EIF4G3 ZHX1

1.00e-031497721031527615
Pubmed

Detection of genes regulated by Lmx1b during limb dorsalization.

COL11A2 KERA

1.04e-032372222417325
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

RBSN OSCAR CRAMP1 SLC45A4

1.09e-0321772434048709
Pubmed

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.

CAND1 AP1B1 AP2B1

1.09e-039772322360420
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

CYLD RBSN CAND1 INPP5B EXD2 VPS13A EIF4G3

1.13e-0377772735844135
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

AP1B1 AP2B1 DAXX CBX4

1.18e-0322272437071664
Pubmed

Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins.

AP1B1 AP2B1

1.23e-032572220594957
Pubmed

Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.

COL11A2 IL18RAP

1.23e-032572219180518
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

DNAH5 DNAH11

1.23e-032572227340223
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CYLD SMG7 GNPTAB MACF1

1.24e-0322572412168954
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

DCAF1 FAM114A2 HSF2 CRAMP1

1.26e-0322672431452512
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

GNPTAB MACF1 ZMIZ1

1.30e-0310372310574462
Pubmed

The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.

AP1B1 AP2B1

1.33e-032672223077317
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

AP1B1 AP2B1 INPP5B ATP2B4

1.35e-0323072435449600
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CYLD SMG7 AP1B1 AP2B1 NAF1 DAXX FBLIM1 STAT2

1.36e-03103872826673895
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ANO7 CRAMP1 SLC45A4 DNAH11

1.41e-0323372437704626
Pubmed

MxA interacts with and is modified by the SUMOylation machinery.

DAXX CBX4

1.43e-032772225447205
Pubmed

Structure--function relationships in HIV-1 Nef.

AP1B1 AP2B1

1.43e-032772211463741
Pubmed

Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.

PHRF1 MACF1

1.43e-032772219026994
Pubmed

Genetic link between renal birth defects and congenital heart disease.

AP1B1 AP2B1

1.54e-032872227002738
Pubmed

DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases.

DCAF1 CAND1

1.54e-032872217079684
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 CYLD SYT11 TSPOAP1 MACF1

1.58e-0340772512693553
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CAND1 AP1B1 AP2B1 MACF1 EIF4G3 DNAH6 ATP2B4

1.85e-0384772735235311
Pubmed

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.

COL11A2 DAXX

1.89e-033172226618355
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

CAND1 AP1B1 MTHFD1L

1.96e-0311972335776542
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

AP1B1 AP2B1 VPS13A ATP2B4

1.99e-0325672424189400
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

AP1B1 SYT11 TRIM32 MTHFD1L MACF1

2.00e-0343072532581705
Pubmed

An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells.

RBSN AP2B1

2.01e-033272228388416
GeneFamilyDyneins, axonemal

DNAH5 DNAH6 DNAH8 DNAH11

7.78e-0817454536
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RAPL1 IL18RAP

6.23e-04154521296
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

RBSN PLEKHF1

2.69e-033145281
GeneFamilyCyclins|F-boxes other

FBXO31 FBXO27

4.23e-0339452560
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RAPL1 IL18RAP

4.90e-0342452602
CoexpressionGAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS

MAPK15 RSPH4A FBXO31 INPP5B CFAP221 MACF1 DNAH5 DNAH6 DNAH11

4.59e-06459729M39136
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

SYT11 TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

2.99e-081957279990440bda7fac5d00ef80444fab07459be625e1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYT11 TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

3.10e-08196727418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYT11 TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

3.10e-08196727581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYT11 TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

3.10e-081967276beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYT11 TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

3.10e-08196727c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellwk_20-22-Epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAPK15 RSPH4A CFAP221 LAMB3 DNAH5 DNAH6 DNAH11

3.21e-08197727468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 IQCK DNAH11

3.56e-082007278dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 IQCK DNAH11

3.56e-08200727bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

1.49e-07148726d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

1.49e-07148726c8e93b87212f55774223caa385859c566fa1981f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRIM32 MTHFD1L DISP3 LAMB3 EIF4G3 DNAH11

1.56e-071497266e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

1.89e-071547269ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

1.89e-0715472658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

4.15e-07176726ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

4.43e-07178726d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

4.58e-07179726d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

4.58e-071797268a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

4.58e-071797265e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

4.73e-071807261f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A CFAP221 DNAH5 TMEM132B DNAH11

4.89e-07181726e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A CFAP221 DNAH5 TMEM132B DNAH11

4.89e-0718172611cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A CFAP221 DNAH5 TMEM132B DNAH11

4.89e-071817265ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A TSPOAP1 DNAH5 DNAH6 DNAH11

5.38e-07184726264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A TSPOAP1 DNAH5 DNAH6 DNAH11

5.38e-07184726d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

SYT11 TSPOAP1 GNPTAB MACF1 IL18RAP ATP2B4

5.38e-07184726791f1bcb954aadc63d4117c400537d036f68734d
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 RSPH4A TSPOAP1 DNAH5 DNAH6 DNAH11

5.38e-0718472622010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

5.56e-071857265e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.11e-071887266833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.11e-07188726803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellMulticiliated|World / shred by cell class for nasal brushing

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.30e-0718972634b110aef839376228c5a403a6b5047a945f472b
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-071917267b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-071917262a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-0719172646c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-071917269f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-071917265129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-071917262d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726b78547dae8328244a47c83346447bdd787efbcae
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.70e-07191726cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellmulticiliated|World / shred by cell class for turbinate

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

6.90e-071927260f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.12e-071937263e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.12e-07193726e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TBC1D8 MAPK15 CFAP221 DNAH5 DNAH6 DNAH11

7.12e-07193726ea345d34440b25f65358a53dc72831998d1c3620
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.12e-07193726aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.12e-07193726bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.34e-07194726756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.34e-0719472643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-071957260e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-07195726581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-0719572693b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

7.56e-0719572679dc031258579ea328181dda33710dd897f1064a
ToppCell18-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-071957263441381759cd00d125752401dc99b78be1c78f88
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-071957263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-07195726e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.56e-0719572607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-07196726de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-07196726686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-0719672667aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-07196726ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-071967261cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-07196726d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

7.79e-0719672669f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

8.02e-0719772691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.02e-0719772671fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

8.02e-0719772622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

8.02e-071977263bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.02e-07197726e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D8 MAPK15 RSPH4A DNAH5 DNAH6 DNAH11

8.02e-0719772687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.02e-07197726d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

MCF2 LAMB3 MACF1 EIF4G3 IL18RAP ATP2B4

8.26e-0719872676d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellwk_20-22-Epithelial-Proximal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.26e-0719872616c54b884500066ade05a406915f9569ca8abdfc
ToppCelldistal-Epithelial-Ciliated-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.26e-07198726d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-07199726b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCellmedial-Epithelial-Ciliated-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-07199726526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-071997262de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

8.51e-07199726e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellmedial-Epithelial-Ciliated|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-07199726a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCelldistal-Epithelial-Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-0719972618ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCellmedial-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-07199726c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCelldistal-Epithelial-Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-071997266ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

TSPOAP1 PLEKHF1 GNPTAB MACF1 IL18RAP ATP2B4

8.51e-071997265f914962e2572b0c6372465b81b7496fa663d93c
ToppCelldistal-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.51e-0719972697b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-07200726cc906ff02fd335ff633b3b97afceb670494f910a
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-0720072652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-0720072679e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-0720072655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-072007266a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-0720072631d75c26055177d656df1fbb10b764cebd61e122
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-07200726721371698bce8890853fb6b6b01a2c20293b39e9
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-07200726cf71c3f6281650940f3ade04ea62be3f340bfc68
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-072007265abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-072007267cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-07200726e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MAPK15 RSPH4A CFAP221 DNAH5 DNAH6 DNAH11

8.76e-072007269c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
DrugPivampicillin [33817-20-8]; Down 200; 8.6uM; PC3; HT_HG-U133A

CUL5 DCAF1 CYLD UBTD1 AP2B1 INPP5B HSF2

2.37e-061937175046_DN
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; HL60; HT_HG-U133A

CUL5 SPAG4 AP2B1 ST3GAL5 TSPOAP1 FOXO4 CBX4

2.81e-061987171268_UP
DrugTropicamide [1508-75-4]; Down 200; 14uM; HL60; HT_HG-U133A

DCAF1 ST3GAL5 SYT11 MACF1 FAM114A2 EIF4G3 IQCK

2.91e-061997172347_DN
DiseasePrimary Ciliary Dyskinesia

DNAAF5 RSPH4A CFAP221 DNAH5 DNAH11

9.22e-0847705C4551720
DiseasePrimary ciliary dyskinesia

DNAAF5 RSPH4A DNAH5 DNAH11

1.62e-0636704cv:C0008780
DiseaseKartagener syndrome (implicated_via_orthology)

AP1B1 DNAH5 DNAH11

4.57e-0614703DOID:0050144 (implicated_via_orthology)
DiseaseBronchiectasis

RSPH4A DNAH5 DNAH11

1.91e-0522703C0006267
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

3.32e-054702DOID:0050144 (is_implicated_in)
Diseasevisceral heterotaxy (implicated_via_orthology)

AP1B1 DNAH5 DNAH11

9.38e-0537703DOID:0050545 (implicated_via_orthology)
DiseaseCiliopathies

TRIM32 DNAH5 DNAH8 DNAH11

1.39e-04110704C4277690
DiseaseAmelogenesis imperfecta

LAMB3 WDR72

7.37e-0417702cv:C0002452
DiseaseLung diseases

RSPH4A DNAH5 DNAH11

8.56e-0478703C0024115
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

AP1B1 DNAH5

9.24e-0419702DOID:9562 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
DIPTDLLPDISIEFL

SYT11

366

Q9BT88
ILLDTRFELPLDIPE

UNC13A

121

Q9UPW8
PLLEVEEEPVSLELG

DISP3

671

Q9P2K9
PLISEETDLIEPTLL

AP2B1

546

P63010
SLPTELEDLIPEVEE

CUL5

546

Q93034
ENLEETIDPVLDPLL

DNAH11

3541

Q96DT5
PLISEETDLIEPTLL

AP1B1

546

Q10567
LPPDSSEAEIIDEIL

MTHFD1L

131

Q6UB35
EDVPLLEDIPLLEDV

CDR1

11

P51861
LEDIPLLEDVPLLED

CDR1

16

P51861
LLEDVPLLEDVPLLE

CDR1

21

P51861
PLLEDVPLLEDTSRL

CDR1

26

P51861
LFELEIEALPLDTPS

DAXX

566

Q9UER7
EFAIEEELPRTPLLD

ATP2B4

1171

P23634
SGPEAEEPIEEELLL

RBSN

726

Q9H1K0
DDLLTSLPPELADLS

TSPOAP1

721

O95153
PIPLSLLLTEEEAAL

IQCK

206

Q8N0W5
RLLDLLVPDIPESVE

ANO7

866

Q6IWH7
LSSEPLLPLDEEAVD

DCAF1

201

Q9Y4B6
PDILDPVEDTLEVEL

IL18RAP

251

O95256
EILENSESLLEPPDR

JPH2

441

Q9BR39
ITLLPEAEILFEDIP

GNPTAB

656

Q3T906
EDLVLLEPLVEESLL

MYO1A

11

Q9UBC5
LETIPPPSEEDLLAL

MAPK15

231

Q8TD08
LAEAPTLPLIEELLE

BMP15

36

O95972
TLPLIEELLEESPGE

BMP15

41

O95972
DAVLDELPPLISESD

CAND1

691

Q86VP6
PLDSLPELQRESSLE

C9orf131

391

Q5VYM1
IEPLLRSELEDFPVL

EXD2

91

Q9NVH0
SLLELPPELLVEIFA

FBXO31

66

Q5XUX0
LSPLRPESEVLAEEI

FOXO4

271

P98177
DIEDFLLPTREPEIL

IL1RAPL1

166

Q9NZN1
PLLIEDIHEELDPAL

DNAH8

3511

Q96JB1
EILESSLLPPLEEEQ

COL11A2

301

P13942
DLEEEPVPDLLGSIL

PHRF1

496

Q9P1Y6
EELLDPELHVLITPS

MACF1

296

O94854
SDVLELLVTEELPRP

OSCAR

116

Q8IYS5
PLDDPDTRQALLELL

CMPK2

136

Q5EBM0
PVLLEELKETLDPAL

DNAH6

3121

Q9C0G6
ELKETLDPALEPILL

DNAH6

3126

Q9C0G6
DEILESLPPEVLSIE

KLHL11

586

Q9NVR0
GQLPDLEDELSLLDP

CRAMP1

546

Q96RY5
ALPQPEVILLDSDLD

CBX4

456

O00257
EVILLDSDLDEPIDL

CBX4

461

O00257
DIETPLLTEAAPILE

FAM114A2

6

Q9NRY5
ETELPDDIPSIEEIL

MCF2

121

P10911
SILPEAISLLLLPEE

ITIH6

991

Q6UXX5
VLDGEDVLPDLDLLP

FBLIM1

91

Q8WUP2
EPILDLPLETISELT

INPP5B

796

P32019
SPIPENELLLEEIEL

KANK4

291

Q5T7N3
QLDLPLEEETLSLPR

LAMB3

666

Q13751
LIPLLLSSLNDEVPE

DNAAF5

286

Q86Y56
PSLELNITDLLEDTP

CYLD

771

Q9NQC7
EEALDLSQLPPELLL

FBXO27

21

Q8NI29
LPLTLELEILENPPE

EIF4G3

381

O43432
PLLIEDVGEELDPAL

DNAH5

3646

Q8TE73
IEVDELLDSSLDPEP

HSF2

481

Q03933
SELFLEELDELPPLS

MTERF3

106

Q96E29
PAILDALPEEDRLET

CFAP221

756

Q4G0U5
PLEEVTLELLPETLQ

PLEKHF1

81

Q96S99
EVGLPLLTPISEDLE

RSPH4A

586

Q5TD94
EEPELTASLPRELTL

TRIM32

261

Q13049
PELESLELELGLVPE

STAT2

716

P52630
SGLDLEPEEEIPALL

TMEM132B

196

Q14DG7
ITEIPELILEDPSEA

SMG7

486

Q92540
LFLEDNELEEVPSPL

KERA

126

O60938
PPTLLDEVELLDLES

SLAIN1

161

Q8ND83
VQTLLELLPEHDLPE

ST3GAL5

171

Q9UNP4
EEPLDLLPTLDLRQE

SPAG4

111

Q9NPE6
EPLELTLPVELLADT

BPIFB2

106

Q8N4F0
LHVPDTALDLEPELL

SLC45A4

311

Q5BKX6
IPLLELPSVSEDDSE

VPS13A

826

Q96RL7
VIPEVSILPEDLEEL

TBC1D8

806

O95759
LPDLPDLSDLDSILT

TRPC5OS

61

A6NMA1
LENLVELLLPTPLSD

WDR72

686

Q3MJ13
DLELISDLDEGPPVL

ZHX1

21

Q9UKY1
LLLEHTEEESLEPPE

UBTD1

126

Q9HAC8
LDLLPELTNPDELLS

ZMIZ1

1031

Q9ULJ6
ELPSVEELTIILPED

NAF1

181

Q96HR8